Year |
Citation |
Score |
2024 |
Chen Y, Gustafsson J, Yang J, Nielsen J, Kerkhoven EJ. Single-cell omics analysis with genome-scale metabolic modeling. Current Opinion in Biotechnology. 86: 103078. PMID 38359604 DOI: 10.1016/j.copbio.2024.103078 |
0.311 |
|
2024 |
Chen Y, Gustafsson J, Tafur Rangel A, Anton M, Domenzain I, Kittikunapong C, Li F, Yuan L, Nielsen J, Kerkhoven EJ. Reconstruction, simulation and analysis of enzyme-constrained metabolic models using GECKO Toolbox 3.0. Nature Protocols. PMID 38238583 DOI: 10.1038/s41596-023-00931-7 |
0.312 |
|
2023 |
Yang H, Li X, Jin H, Turkez H, Ozturk G, Doganay HL, Zhang C, Nielsen J, Uhlén M, Borén J, Mardinoglu A. Longitudinal metabolomics analysis reveals the acute effect of cysteine and NAC included in the combined metabolic activators. Free Radical Biology & Medicine. 204: 347-358. PMID 37245532 DOI: 10.1016/j.freeradbiomed.2023.05.013 |
0.301 |
|
2023 |
Qin N, Li L, Ji X, Pereira R, Chen Y, Yin S, Li C, Wan X, Qiu D, Jiang J, Luo H, Zhang Y, Dong G, Zhang Y, Shi S, ... ... Nielsen J, et al. Flux regulation through glycolysis and respiration is balanced by inositol pyrophosphates in yeast. Cell. PMID 36758548 DOI: 10.1016/j.cell.2023.01.014 |
0.323 |
|
2022 |
Luo H, Li P, Ji B, Nielsen J. Modeling the metabolic dynamics at the genome-scale by optimized yield analysis. Metabolic Engineering. 75: 119-130. PMID 36503050 DOI: 10.1016/j.ymben.2022.12.001 |
0.317 |
|
2022 |
Cao X, Yu W, Chen Y, Yang S, Zhao ZK, Nielsen J, Luan H, Zhou YJ. Engineering yeast for high-level production of diterpenoid sclareol. Metabolic Engineering. PMID 36371032 DOI: 10.1016/j.ymben.2022.11.002 |
0.355 |
|
2022 |
Lu H, Kerkhoven EJ, Nielsen J. A Pan-Draft Metabolic Model Reflects Evolutionary Diversity across 332 Yeast Species. Biomolecules. 12. PMID 36358981 DOI: 10.3390/biom12111632 |
0.306 |
|
2022 |
Yu T, Liu Q, Wang X, Liu X, Chen Y, Nielsen J. Metabolic reconfiguration enables synthetic reductive metabolism in yeast. Nature Metabolism. PMID 36302903 DOI: 10.1038/s42255-022-00654-1 |
0.314 |
|
2022 |
Ishchuk OP, Domenzain I, Sánchez BJ, Muñiz-Paredes F, Martínez JL, Nielsen J, Petranovic D. Genome-scale modeling drives 70-fold improvement of intracellular heme production in . Proceedings of the National Academy of Sciences of the United States of America. 119: e2108245119. PMID 35858410 DOI: 10.1073/pnas.2108245119 |
0.318 |
|
2022 |
Domenzain I, Sánchez B, Anton M, Kerkhoven EJ, Millán-Oropeza A, Henry C, Siewers V, Morrissey JP, Sonnenschein N, Nielsen J. Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0. Nature Communications. 13: 3766. PMID 35773252 DOI: 10.1038/s41467-022-31421-1 |
0.335 |
|
2022 |
Chen Y, Li F, Nielsen J. Genome-scale modeling of yeast metabolism: retrospectives and perspectives. Fems Yeast Research. PMID 35094064 DOI: 10.1093/femsyr/foac003 |
0.33 |
|
2020 |
Hellgren J, Godina A, Nielsen J, Siewers V. Promiscuous phosphoketolase and metabolic rewiring enables novel non-oxidative glycolysis in yeast for high-yield production of acetyl-CoA derived products. Metabolic Engineering. 62: 150-160. PMID 32911054 DOI: 10.1016/J.Ymben.2020.09.003 |
0.386 |
|
2020 |
Hu Y, Zhu Z, Gradischnig D, Winkler M, Nielsen J, Siewers V. Engineering carboxylic acid reductase for selective synthesis of medium-chain fatty alcohols in yeast. Proceedings of the National Academy of Sciences of the United States of America. PMID 32873649 DOI: 10.1073/Pnas.2010521117 |
0.361 |
|
2020 |
Hou J, Nielsen J. Editorial: yeast synthetic biology. Fems Yeast Research. 20. PMID 32854113 DOI: 10.1093/Femsyr/Foaa049 |
0.326 |
|
2020 |
Björkeroth J, Campbell K, Malina C, Yu R, Di Bartolomeo F, Nielsen J. Proteome reallocation from amino acid biosynthesis to ribosomes enables yeast to grow faster in rich media. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817546 DOI: 10.1073/Pnas.1921890117 |
0.349 |
|
2020 |
Van Olden CC, Van de Laar AW, Meijnikman AS, Aydin O, Van Olst N, Hoozemans JB, De Brauw LM, Bruin SC, Acherman Y, Verheij J, Pyykkö JE, Hagedoorn M, Sanderman R, Bosma NC, Tremaroli V, ... ... Nielsen J, et al. A Systems Biology approach to understand gut microbiota and host metabolism in morbid obesity: design of the BARIA Longitudinal Cohort Study. Journal of Internal Medicine. PMID 32640105 DOI: 10.1111/Joim.13157 |
0.308 |
|
2020 |
Babaei M, Borja Zamfir GM, Chen X, Bjerre Christensen H, Kristensen M, Nielsen J, Borodina I. Metabolic engineering of Saccharomyces cerevisiae for rosmarinic acid production. Acs Synthetic Biology. PMID 32589831 DOI: 10.1021/Acssynbio.0C00048 |
0.343 |
|
2020 |
Nilsson A, Haanstra JR, Engqvist M, Gerding A, Bakker BM, Klingmüller U, Teusink B, Nielsen J. Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 32341162 DOI: 10.1073/Pnas.1919250117 |
0.337 |
|
2020 |
Zhang C, Bjornson E, Arif M, Tebani A, Lovric A, Benfeitas R, Ozcan M, Juszczak K, Kim W, Kim JT, Bidkhori G, Ståhlman M, Bergh PO, Adiels M, Turkez H, ... ... Nielsen J, et al. The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alc33oholic fatty liver disease. Molecular Systems Biology. 16: e9495. PMID 32337855 DOI: 10.15252/Msb.209495 |
0.363 |
|
2020 |
Yu R, Campbell K, Pereira R, Björkeroth J, Qi Q, Vorontsov E, Sihlbom C, Nielsen J. Nitrogen limitation reveals large reserves in metabolic and translational capacities of yeast. Nature Communications. 11: 1881. PMID 32312967 DOI: 10.1038/S41467-020-15749-0 |
0.386 |
|
2020 |
Lieven C, Beber ME, Olivier BG, Bergmann FT, Ataman M, Babaei P, Bartell JA, Blank LM, Chauhan S, Correia K, Diener C, Dräger A, Ebert BE, Edirisinghe JN, Faria JP, ... ... Nielsen J, et al. Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing. Nature Biotechnology. 38: 504. PMID 32265554 DOI: 10.1038/S41587-020-0477-4 |
0.52 |
|
2020 |
Robinson JL, Kocabaş P, Wang H, Cholley PE, Cook D, Nilsson A, Anton M, Ferreira R, Domenzain I, Billa V, Limeta A, Hedin A, Gustafsson J, Kerkhoven EJ, Svensson LT, ... ... Nielsen J, et al. An atlas of human metabolism. Science Signaling. 13. PMID 32209698 DOI: 10.1126/Scisignal.Aaz1482 |
0.522 |
|
2020 |
Lam S, Doran S, Yuksel HH, Altay O, Turkez H, Nielsen J, Boren J, Uhlen M, Mardinoglu A. Addressing the heterogeneity in liver diseases using biological networks. Briefings in Bioinformatics. PMID 32201876 DOI: 10.1093/Bib/Bbaa002 |
0.337 |
|
2020 |
Lieven C, Beber ME, Olivier BG, Bergmann FT, Ataman M, Babaei P, Bartell JA, Blank LM, Chauhan S, Correia K, Diener C, Dräger A, Ebert BE, Edirisinghe JN, Faria JP, ... ... Nielsen J, et al. MEMOTE for standardized genome-scale metabolic model testing. Nature Biotechnology. PMID 32123384 DOI: 10.1038/S41587-020-0446-Y |
0.533 |
|
2020 |
Gutierrez JM, Feizi A, Li S, Kallehauge TB, Hefzi H, Grav LM, Ley D, Baycin Hizal D, Betenbaugh MJ, Voldborg B, Faustrup Kildegaard H, Min Lee G, Palsson BO, Nielsen J, Lewis NE. Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion. Nature Communications. 11: 68. PMID 31896772 DOI: 10.1038/S41467-019-13867-Y |
0.529 |
|
2020 |
Anton M, Cholley P, Robinson JL, Huang S, Svensson LT, Nielsen J. Metabolic Atlas – a website for exploration and visualization of metabolic networks F1000research. 9. DOI: 10.7490/F1000Research.1117998.1 |
0.333 |
|
2020 |
Cook D, Nielsen J, Braun E. A systems medicine-based approach for finding metabolic targets applied to primary basal-like breast cancer. Journal of Clinical Oncology. 38. DOI: 10.1200/Jco.2020.38.15_Suppl.E12590 |
0.324 |
|
2019 |
Borja GM, Rodriguez A, Campbell K, Borodina I, Chen Y, Nielsen J. Metabolic engineering and transcriptomic analysis of Saccharomyces cerevisiae producing p-coumaric acid from xylose. Microbial Cell Factories. 18: 191. PMID 31690329 DOI: 10.1186/S12934-019-1244-4 |
0.339 |
|
2019 |
Yu R, Nielsen J. Big data in yeast systems biology. Fems Yeast Research. PMID 31603503 DOI: 10.1093/Femsyr/Foz070 |
0.377 |
|
2019 |
Ferreira R, Skrekas C, Hedin A, Sánchez BJ, Siewers V, Nielsen J, David F. Model-assisted fine-tuning of central carbon metabolism in yeast through dCas9-based regulation. Acs Synthetic Biology. PMID 31577419 DOI: 10.1021/acssynbio.9b00258 |
0.329 |
|
2019 |
Pereira R, Wei Y, Mohamed E, Radi M, Malina C, Herrgård MJ, Feist AM, Nielsen J, Chen Y. Adaptive laboratory evolution of tolerance to dicarboxylic acids in Saccharomyces cerevisiae. Metabolic Engineering. PMID 31550508 DOI: 10.1016/J.Ymben.2019.09.008 |
0.323 |
|
2019 |
Tiukova IA, Prigent S, Nielsen J, Sandgren M, Kerkhoven EJ. Genome-scale model of Rhodotorula toruloides metabolism. Biotechnology and Bioengineering. 116: 3396-3408. PMID 31502665 DOI: 10.1002/Bit.27162 |
0.418 |
|
2019 |
Lu H, Li F, Sánchez BJ, Zhu Z, Li G, Domenzain I, Marcišauskas S, Anton PM, Lappa D, Lieven C, Beber ME, Sonnenschein N, Kerkhoven EJ, Nielsen J. A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism. Nature Communications. 10: 3586. PMID 31395883 DOI: 10.1038/S41467-019-11581-3 |
0.422 |
|
2019 |
Dabirian Y, Gonçalves Teixeira P, Nielsen J, Siewers V, David F. FadR-based biosensor assisted screening for genes enhancing fatty acyl-CoA pools in Saccharomyces cerevisiae. Acs Synthetic Biology. PMID 31314504 DOI: 10.1021/Acssynbio.9B00118 |
0.349 |
|
2019 |
Tiukova IA, Brandenburg J, Blomqvist J, Sampels S, Mikkelsen N, Skaugen M, Arntzen MØ, Nielsen J, Sandgren M, Kerkhoven EJ. Proteome analysis of xylose metabolism in Rhodotorula toruloides during lipid production. Biotechnology For Biofuels. 12: 137. PMID 31171938 DOI: 10.1186/S13068-019-1478-8 |
0.385 |
|
2019 |
Hu Y, Zhu Z, Nielsen J, Siewers V. Engineering Saccharomyces cerevisiae cells for production of fatty acid-derived biofuels and chemicals. Open Biology. 9: 190049. PMID 31088249 DOI: 10.1098/Rsob.190049 |
0.367 |
|
2019 |
Nielsen JC, Prigent S, Grijseels S, Workman M, Ji B, Nielsen J. Comparative Transcriptome Analysis Shows Conserved Metabolic Regulation during Production of Secondary Metabolites in Filamentous Fungi. Msystems. 4. PMID 31020039 DOI: 10.1128/mSystems.00012-19 |
0.318 |
|
2019 |
Wang G, Björk SM, Huang M, Liu Q, Campbell K, Nielsen J, Joensson HN, Petranovic D. RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in . Proceedings of the National Academy of Sciences of the United States of America. PMID 31000602 DOI: 10.1073/Pnas.1820561116 |
0.352 |
|
2019 |
Pereira R, Vilaça P, Maia P, Nielsen J, Rocha I. TDPS - Turnover dependent phenotypic simulation: a quantitative constraint-based simulation method that accommodates all main strain design strategies. Acs Synthetic Biology. PMID 30925047 DOI: 10.1021/Acssynbio.8B00248 |
0.386 |
|
2019 |
Li X, Chen Y, Nielsen J. Harnessing xylose pathways for biofuels production. Current Opinion in Biotechnology. 57: 56-65. PMID 30785001 DOI: 10.1016/j.copbio.2019.01.006 |
0.304 |
|
2019 |
Bauer J, Brambilla L, Duboc P, Francois JM, Gancedo C, Giuseppin ML, Heijnen JJ, Hoare M, Lange HC, Madden EA, Niederberger P, Nielsen J, Parrou JL, Petit T, Porro D, et al. An interlaboratory comparison of physiological and genetic properties of four Saccharomyces cerevisiae strains. Enzyme and Microbial Technology. 26: 706-714. PMID 10862876 DOI: 10.1016/S0141-0229(00)00162-9 |
0.336 |
|
2018 |
Bidkhori G, Benfeitas R, Klevstig M, Zhang C, Nielsen J, Uhlen M, Boren J, Mardinoglu A. Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes. Proceedings of the National Academy of Sciences of the United States of America. 115: E11874-E11883. PMID 30482855 DOI: 10.1073/Pnas.1807305115 |
0.356 |
|
2018 |
Huang M, Wang G, Qin J, Petranovic D, Nielsen J. Engineering the protein secretory pathway of enables improved protein production. Proceedings of the National Academy of Sciences of the United States of America. PMID 30397111 DOI: 10.1073/Pnas.1809921115 |
0.345 |
|
2018 |
Wang H, Marcišauskas S, Sánchez BJ, Domenzain I, Hermansson D, Agren R, Nielsen J, Kerkhoven EJ. RAVEN 2.0: A versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor. Plos Computational Biology. 14: e1006541. PMID 30335785 DOI: 10.1371/Journal.Pcbi.1006541 |
0.352 |
|
2018 |
Yu T, Zhou YJ, Huang M, Liu Q, Pereira R, David F, Nielsen J. Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis. Cell. PMID 30100189 DOI: 10.1016/J.Cell.2018.07.013 |
0.441 |
|
2018 |
Dai Z, Huang M, Chen Y, Siewers V, Nielsen J. Global rewiring of cellular metabolism renders Saccharomyces cerevisiae Crabtree negative. Nature Communications. 9: 3059. PMID 30076310 DOI: 10.1038/s41467-018-05409-9 |
0.311 |
|
2018 |
Yu T, Zhou YJ, Wenning L, Liu Q, Krivoruchko A, Siewers V, Nielsen J, David F. Author Correction: Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals. Nature Communications. 9: 16220. PMID 30004090 DOI: 10.1038/Ncomms16220 |
0.342 |
|
2018 |
Teixeira PG, David F, Siewers V, Nielsen J. Engineering lipid droplet assembly mechanisms for improved triacylglycerol accumulation in Saccharomyces cerevisiae. Fems Yeast Research. 18. PMID 29897501 DOI: 10.1093/Femsyr/Foy060 |
0.387 |
|
2018 |
Ferreira R, Teixeira PG, Gossing M, David F, Siewers V, Nielsen J. Metabolic engineering of for overproduction of triacylglycerols. Metabolic Engineering Communications. 6: 22-27. PMID 29896445 DOI: 10.1016/J.Meteno.2018.01.002 |
0.418 |
|
2018 |
Rola-Łuszczak M, Materniak-Kornas M, Pluta A, Podgórska K, Nielsen J, Stadejek T, Kuźmak J. Transcriptional profiles of PBMCs from pigs infected with three genetically diverse porcine reproductive and respiratory syndrome virus strains. Molecular Biology Reports. 45: 675-688. PMID 29882085 DOI: 10.1007/S11033-018-4204-X |
0.315 |
|
2018 |
Prigent S, Nielsen JC, Frisvad JC, Nielsen J. Reconstruction of 24 Penicillium genome-scale metabolic models shows diversity based on their secondary metabolism. Biotechnology and Bioengineering. 115: 2604-2612. PMID 29873086 DOI: 10.1002/bit.26739 |
0.305 |
|
2018 |
Maury J, Kannan S, Jensen NB, Öberg FK, Kildegaard KR, Forster J, Nielsen J, Workman CT, Borodina I. Glucose-Dependent Promoters for Dynamic Regulation of Metabolic Pathways. Frontiers in Bioengineering and Biotechnology. 6: 63. PMID 29872655 DOI: 10.3389/Fbioe.2018.00063 |
0.699 |
|
2018 |
Bao J, Huang M, Petranovic D, Nielsen J. Balanced trafficking between the ER and the Golgi apparatus increases protein secretion in yeast. Amb Express. 8: 37. PMID 29532188 DOI: 10.1186/S13568-018-0571-X |
0.314 |
|
2018 |
Brunk E, Sahoo S, Zielinski DC, Altunkaya A, Dräger A, Mih N, Gatto F, Nilsson A, Preciat Gonzalez GA, Aurich MK, Prlić A, Sastry A, Danielsdottir AD, Heinken A, Noronha A, ... ... Nielsen J, et al. Recon3D enables a three-dimensional view of gene variation in human metabolism. Nature Biotechnology. PMID 29457794 DOI: 10.1038/Nbt.4072 |
0.569 |
|
2018 |
Mardinoglu A, Wu H, Bjornson E, Zhang C, Hakkarainen A, Räsänen SM, Lee S, Mancina RM, Bergentall M, Pietiläinen KH, Söderlund S, Matikainen N, Ståhlman M, Bergh PO, Adiels M, ... ... Nielsen J, et al. An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans. Cell Metabolism. PMID 29456073 DOI: 10.1016/J.Cmet.2018.01.005 |
0.312 |
|
2018 |
Ferreira R, Teixeira PG, Siewers V, Nielsen J. Redirection of lipid flux toward phospholipids in yeast increases fatty acid turnover and secretion. Proceedings of the National Academy of Sciences of the United States of America. PMID 29358378 DOI: 10.1073/Pnas.1715282115 |
0.384 |
|
2018 |
Bergenholm D, Gossing M, Wei Y, Siewers V, Nielsen J. Modulation of saturation and chain length of fatty acids in Saccharomyces cerevisiae for production of cocoa butter-like lipids. Biotechnology and Bioengineering. PMID 29313898 DOI: 10.1002/Bit.26518 |
0.302 |
|
2018 |
Huang M, Joensson HN, Nielsen J. High-Throughput Microfluidics for the Screening of Yeast Libraries. Methods in Molecular Biology (Clifton, N.J.). 1671: 307-317. PMID 29170967 DOI: 10.1007/978-1-4939-7295-1_19 |
0.348 |
|
2018 |
Zhou YJ, Kerkhoven EJ, Nielsen J. Barriers and opportunities in bio-based production of hydrocarbons Nature Energy. 3: 925-935. DOI: 10.1038/S41560-018-0197-X |
0.321 |
|
2017 |
Nilsson A, Nielsen J, Palsson BO. Metabolic Models of Protein Allocation Call for the Kinetome. Cell Systems. 5: 538-541. PMID 29284126 DOI: 10.1016/J.Cels.2017.11.013 |
0.447 |
|
2017 |
Zhou YJ, Hu Y, Zhu Z, Siewers V, Nielsen J. Dynamic engineering of 1-alkenes biosynthesis and secretion in yeast. Acs Synthetic Biology. PMID 29284088 DOI: 10.1021/Acssynbio.7B00338 |
0.378 |
|
2017 |
Zhao X, Nielsen J. Metabolic engineering frontiers emerging with advanced tools and methodologies. Biotechnology Advances. PMID 29107149 DOI: 10.1016/J.Biotechadv.2017.10.007 |
0.339 |
|
2017 |
Rodriguez A, Chen Y, Khoomrung S, Özdemir E, Borodina I, Nielsen J. Comparison of the metabolic response to over-production of p-coumaric acid in two yeast strains. Metabolic Engineering. PMID 29101089 DOI: 10.1016/J.Ymben.2017.10.013 |
0.396 |
|
2017 |
Huang M, Bao J, Hallström BM, Petranovic D, Nielsen J. Efficient protein production by yeast requires global tuning of metabolism. Nature Communications. 8: 1131. PMID 29070809 DOI: 10.1038/S41467-017-00999-2 |
0.39 |
|
2017 |
Nielsen JC, Nielsen J. Development of fungal cell factories for the production of secondary metabolites: Linking genomics and metabolism. Synthetic and Systems Biotechnology. 2: 5-12. PMID 29062956 DOI: 10.1016/j.synbio.2017.02.002 |
0.312 |
|
2017 |
Zhu Z, Zhou YJ, Kang MK, Krivoruchko A, Buijs NA, Nielsen J. Enabling the synthesis of medium chain alkanes and 1-alkenes in yeast. Metabolic Engineering. PMID 28939277 DOI: 10.1016/J.Ymben.2017.09.007 |
0.316 |
|
2017 |
Liu G, Chen Y, Færgeman NJ, Nielsen J. Elimination of the last reactions in ergosterol biosynthesis alters the resistance of Saccharomyces cerevisiae to multiple stresses. Fems Yeast Research. 17. PMID 28910986 DOI: 10.1093/Femsyr/Fox063 |
0.301 |
|
2017 |
Gong Z, Nielsen J, Zhou YJ. Engineering robustness of microbial cell factories. Biotechnology Journal. PMID 28857502 DOI: 10.1002/Biot.201700014 |
0.389 |
|
2017 |
Sánchez BJ, Zhang C, Nilsson A, Lahtvee PJ, Kerkhoven EJ, Nielsen J. Improving the phenotype predictions of a yeast genome-scale metabolic model by incorporating enzymatic constraints. Molecular Systems Biology. 13: 935. PMID 28779005 DOI: 10.15252/Msb.20167411 |
0.434 |
|
2017 |
Cook DJ, Nielsen J. Genome-scale metabolic models applied to human health and disease. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. PMID 28644920 DOI: 10.1002/Wsbm.1393 |
0.372 |
|
2017 |
Kerkhoven EJ, Kim YM, Wei S, Nicora CD, Fillmore TL, Purvine SO, Webb-Robertson BJ, Smith RD, Baker SE, Metz TO, Nielsen J. Leucine Biosynthesis Is Involved in Regulating High Lipid Accumulation in Yarrowia lipolytica. Mbio. 8. PMID 28634240 DOI: 10.1128/Mbio.00857-17 |
0.362 |
|
2017 |
Rodriguez A, Strucko T, Stahlhut SG, Kristensen M, Svenssen DK, Forster J, Nielsen J, Borodina I. Metabolic engineering of yeast for fermentative production of flavonoids. Bioresource Technology. PMID 28634125 DOI: 10.1016/J.Biortech.2017.06.043 |
0.707 |
|
2017 |
Yu T, Zhou YJ, Wenning L, Liu Q, Krivoruchko A, Siewers V, Nielsen J, David F. Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals. Nature Communications. 8: 15587. PMID 28548095 DOI: 10.1038/Ncomms15587 |
0.377 |
|
2017 |
Hu Y, Zhou YJ, Bao J, Huang L, Nielsen J, Krivoruchko A. Metabolic engineering of Saccharomyces cerevisiae for production of germacrene A, a precursor of beta-elemene. Journal of Industrial Microbiology & Biotechnology. PMID 28547322 DOI: 10.1007/S10295-017-1934-Z |
0.338 |
|
2017 |
Nielsen J, Archer J, Essack M, Bajic VB, Gojobori T, Mijakovic I. Building a bio-based industry in the Middle East through harnessing the potential of the Red Sea biodiversity. Applied Microbiology and Biotechnology. PMID 28528426 DOI: 10.1007/S00253-017-8310-9 |
0.312 |
|
2017 |
Kang MK, Zhou YJ, Buijs NA, Nielsen J. Functional screening of aldehyde decarbonylases for long-chain alkane production by Saccharomyces cerevisiae. Microbial Cell Factories. 16: 74. PMID 28464872 DOI: 10.1186/S12934-017-0683-Z |
0.314 |
|
2017 |
Chen Y, Wang Y, Nielsen J. Systematic inference of functional phosphorylation events in yeast metabolism. Bioinformatics (Oxford, England). PMID 28334215 DOI: 10.1093/Bioinformatics/Btx110 |
0.32 |
|
2017 |
Teixeira PG, Ferreira R, Zhou YJ, Siewers V, Nielsen J. Dynamic regulation of fatty acid pools for improved production of fatty alcohols in Saccharomyces cerevisiae. Microbial Cell Factories. 16: 45. PMID 28298234 DOI: 10.1186/S12934-017-0663-3 |
0.322 |
|
2017 |
Mardinoglu A, Bjornson E, Zhang C, Klevstig M, Söderlund S, Ståhlman M, Adiels M, Hakkarainen A, Lundbom N, Kilicarslan M, Hallström BM, Lundbom J, Vergès B, Barrett PH, Watts GF, ... ... Nielsen J, et al. Personal model-assisted identification of NAD(+) and glutathione metabolism as intervention target in NAFLD. Molecular Systems Biology. 13: 916. PMID 28254760 DOI: 10.15252/Msb.20167422 |
0.346 |
|
2017 |
Robinson JL, Nielsen J. Anticancer drug discovery through genome-scale metabolic modeling Current Opinion in Systems Biology. 4: 1-8. DOI: 10.1016/J.Coisb.2017.05.007 |
0.372 |
|
2016 |
Martínez JL, Meza E, Petranovic D, Nielsen J. The impact of respiration and oxidative stress response on recombinant α-amylase production by. Metabolic Engineering Communications. 3: 205-210. PMID 29468124 DOI: 10.1016/J.Meteno.2016.06.003 |
0.342 |
|
2016 |
Pereira R, Nielsen J, Rocha I. Improving the flux distributions simulated with genome-scale metabolic models of. Metabolic Engineering Communications. 3: 153-163. PMID 29468121 DOI: 10.1016/j.meteno.2016.05.002 |
0.303 |
|
2016 |
Kerkhoven EJ, Pomraning KR, Baker SE, Nielsen J. Regulation of amino-acid metabolism controls flux to lipid accumulation in Yarrowia lipolytica. Npj Systems Biology and Applications. 2: 16005. PMID 28725468 DOI: 10.1038/npjsba.2016.5 |
0.315 |
|
2016 |
Sweetlove LJ, Nielsen J, Fernie AR. Engineering central metabolism - a grand challenge for plant biologists. The Plant Journal : For Cell and Molecular Biology. PMID 28004455 DOI: 10.1111/tpj.13464 |
0.309 |
|
2016 |
Casey JR, Mardinoglu A, Nielsen J, Karl DM. Adaptive Evolution of Phosphorus Metabolism in Prochlorococcus. Msystems. 1. PMID 27868089 DOI: 10.1128/mSystems.00065-16 |
0.376 |
|
2016 |
Li M, Schneider K, Kristensen M, Borodina I, Nielsen J. Engineering yeast for high-level production of stilbenoid antioxidants. Scientific Reports. 6: 36827. PMID 27833117 DOI: 10.1038/Srep36827 |
0.378 |
|
2016 |
Zhou YJ, Buijs NA, Zhu Z, Gómez DO, Boonsombuti A, Siewers V, Nielsen J. Harnessing yeast peroxisomes for biosynthesis of fatty acid-derived biofuels and chemicals with relieved side-pathway competition. Journal of the American Chemical Society. PMID 27753483 DOI: 10.1021/Jacs.6B07394 |
0.362 |
|
2016 |
Grijseels S, Nielsen JC, Randelovic M, Nielsen J, Nielsen KF, Workman M, Frisvad JC. Penicillium arizonense, a new, genome sequenced fungal species, reveals a high chemical diversity in secreted metabolites. Scientific Reports. 6: 35112-35112. PMID 27739446 DOI: 10.1038/Srep35112 |
0.348 |
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2016 |
Tippmann S, Anfelt J, David F, Rand JM, Siewers V, Uhlén M, Nielsen J, Hudson EP. Affibody scaffolds improve sesquiterpene production in Saccharomyces cerevisiae. Acs Synthetic Biology. PMID 27560952 DOI: 10.1021/Acssynbio.6B00109 |
0.353 |
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2016 |
Gatto F, Schulze A, Nielsen J. Systematic Analysis Reveals that Cancer Mutations Converge on Deregulated Metabolism of Arachidonate and Xenobiotics. Cell Reports. PMID 27396332 DOI: 10.1016/J.Celrep.2016.06.038 |
0.327 |
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2016 |
Zhou YJ, Buijs NA, Zhu Z, Qin J, Siewers V, Nielsen J. Production of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories. Nature Communications. 7: 11709. PMID 27222209 DOI: 10.1038/Ncomms11709 |
0.351 |
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2016 |
Gatto F, Volpi N, Nilsson H, Nookaew I, Maruzzo M, Roma A, Johansson ME, Stierner U, Lundstam S, Basso U, Nielsen J. Glycosaminoglycan Profiling in Patients' Plasma and Urine Predicts the Occurrence of Metastatic Clear Cell Renal Cell Carcinoma. Cell Reports. PMID 27184840 DOI: 10.1016/J.Celrep.2016.04.056 |
0.32 |
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2016 |
Kildegaard KR, Jensen NB, Schneider K, Czarnotta E, Özdemir E, Klein T, Maury J, Ebert BE, Christensen HB, Chen Y, Kim IK, Herrgård MJ, Blank LM, Forster J, Nielsen J, et al. Engineering and systems-level analysis of Saccharomyces cerevisiae for production of 3-hydroxypropionic acid via malonyl-CoA reductase-dependent pathway. Microbial Cell Factories. 15: 53. PMID 26980206 DOI: 10.1186/S12934-016-0451-5 |
0.669 |
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2016 |
Nielsen J, Keasling JD. Engineering Cellular Metabolism. Cell. 164: 1185-97. PMID 26967285 DOI: 10.1016/J.Cell.2016.02.004 |
0.404 |
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2016 |
Maury J, Germann SM, Baallal Jacobsen SA, Jensen NB, Kildegaard KR, Herrgård MJ, Schneider K, Koza A, Forster J, Nielsen J, Borodina I. EasyCloneMulti: A Set of Vectors for Simultaneous and Multiple Genomic Integrations in Saccharomyces cerevisiae. Plos One. 11: e0150394. PMID 26934490 DOI: 10.1371/Journal.Pone.0150394 |
0.722 |
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2016 |
David F, Nielsen J, Siewers V. Flux Control at the Malonyl-CoA Node through Hierarchical Dynamic Pathway Regulation in Saccharomyces cerevisiae. Acs Synthetic Biology. 5: 224-33. PMID 26750662 DOI: 10.1021/acssynbio.5b00161 |
0.304 |
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2016 |
Martínez JL, Petranovic D, Nielsen J. Heme metabolism in stress regulation and protein production: from Cinderella to a key player. Bioengineered. 0. PMID 26731643 DOI: 10.1080/21655979.2015.1126016 |
0.372 |
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2016 |
de Jong BW, Shi S, Valle-Rodríguez JO, Siewers V, Nielsen J. Metabolic pathway engineering for fatty acid ethyl ester production in Saccharomyces cerevisiae using stable chromosomal integration Journal of Industrial Microbiology and Biotechnology. 42: 477-486. PMID 25422103 DOI: 10.1007/S10295-014-1540-2 |
0.403 |
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2016 |
Uhlén M, Hallström BM, Lindskog C, Mardinoglu A, Pontén F, Nielsen J. Transcriptomics resources of human tissues and organs Molecular Systems Biology. 12. DOI: 10.15252/Msb.20155865 |
0.3 |
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2015 |
Ghaffari P, Mardinoglu A, Nielsen J. Cancer Metabolism: A Modeling Perspective Frontiers in Physiology. 6: 382-382. PMID 26733270 DOI: 10.3389/Fphys.2015.00382 |
0.372 |
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2015 |
Shi S, Ji H, Siewers V, Nielsen J. Improved production of fatty acids by Saccharomyces cerevisiae through screening a cDNA library from the oleaginous yeast Yarrowia lipolytica. Fems Yeast Research. PMID 26658002 DOI: 10.1093/Femsyr/Fov108 |
0.351 |
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2015 |
Irani ZA, Kerkhoven E, Shojaosadati SA, Nielsen J. Genome-scale metabolic model of Pichia pastoris with native and humanized glycosylation of recombinant proteins. Biotechnology and Bioengineering. PMID 26480251 DOI: 10.1002/Bit.25863 |
0.354 |
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2015 |
Mardinoglu A, Shoaie S, Bergentall M, Ghaffari P, Zhang C, Larsson E, Bäckhed F, Nielsen J. The gut microbiota modulates host amino acid and glutathione metabolism in mice. Molecular Systems Biology. 11: 834. PMID 26475342 DOI: 10.15252/Msb.20156487 |
0.359 |
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2015 |
Anfelt J, Kaczmarzyk D, Shabestary K, Renberg B, Rockberg J, Nielsen J, Uhlén M, Hudson EP. Genetic and nutrient modulation of acetyl-CoA levels in Synechocystis for n-butanol production. Microbial Cell Factories. 14: 167. PMID 26474754 DOI: 10.1186/S12934-015-0355-9 |
0.394 |
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2015 |
Ebrahim A, Almaas E, Bauer E, Bordbar A, Burgard AP, Chang RL, Dräger A, Famili I, Feist AM, Fleming RM, Fong SS, Hatzimanikatis V, Herrgård MJ, Holder A, Hucka M, ... ... Nielsen J, et al. Do genome-scale models need exact solvers or clearer standards? Molecular Systems Biology. 11: 831. PMID 26467284 DOI: 10.15252/Msb.20156157 |
0.45 |
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2015 |
Mardinoglu A, Heiker JT, Gärtner D, Björnson E, Schön MR, Flehmig G, Klöting N, Krohn K, Fasshauer M, Stumvoll M, Nielsen J, Blüher M. Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue. Scientific Reports. 5: 14841. PMID 26434764 DOI: 10.1038/Srep14841 |
0.33 |
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2015 |
Fletcher E, Feizi A, Kim S, Siewers V, Nielsen J. RNA-seq analysis of Pichia anomala reveals important mechanisms required for survival at low pH. Microbial Cell Factories. 14: 143. PMID 26376644 DOI: 10.1186/S12934-015-0331-4 |
0.307 |
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2015 |
Qin J, Zhou YJ, Krivoruchko A, Huang M, Liu L, Khoomrung S, Siewers V, Jiang B, Nielsen J. Modular pathway rewiring of Saccharomyces cerevisiae enables high-level production of L-ornithine. Nature Communications. 6: 8224. PMID 26345617 DOI: 10.1038/Ncomms9224 |
0.39 |
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2015 |
Li M, Kildegaard KR, Chen Y, Rodriguez A, Borodina I, Nielsen J. De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae. Metabolic Engineering. 32: 1-11. PMID 26344106 DOI: 10.1016/J.Ymben.2015.08.007 |
0.385 |
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2015 |
Nielsen J. BIOENGINEERING. Yeast cell factories on the horizon. Science (New York, N.Y.). 349: 1050-1. PMID 26339012 DOI: 10.1126/Science.Aad2081 |
0.37 |
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2015 |
Rodriguez A, Kildegaard KR, Li M, Borodina I, Nielsen J. Establishment of a yeast platform strain for production of p-coumaric acid through metabolic engineering of aromatic amino acid biosynthesis. Metabolic Engineering. 31: 181-8. PMID 26292030 DOI: 10.1016/J.Ymben.2015.08.003 |
0.358 |
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2015 |
Huang M, Bai Y, Sjostrom SL, Hallström BM, Liu Z, Petranovic D, Uhlén M, Joensson HN, Andersson-Svahn H, Nielsen J. Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast. Proceedings of the National Academy of Sciences of the United States of America. 112: E4689-96. PMID 26261321 DOI: 10.1073/Pnas.1506460112 |
0.367 |
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2015 |
Zhang Y, Liu G, Engqvist MK, Krivoruchko A, Hallström BM, Chen Y, Siewers V, Nielsen J. Adaptive mutations in sugar metabolism restore growth on glucose in a pyruvate decarboxylase negative yeast strain. Microbial Cell Factories. 14: 116. PMID 26253003 DOI: 10.1186/S12934-015-0305-6 |
0.385 |
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2015 |
Shoaie S, Ghaffari P, Kovatcheva-Datchary P, Mardinoglu A, Sen P, Pujos-Guillot E, de Wouters T, Juste C, Rizkalla S, Chilloux J, Hoyles L, Nicholson JK, Dore J, Dumas ME, ... ... Nielsen J, et al. Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome. Cell Metabolism. 22: 320-31. PMID 26244934 DOI: 10.1016/J.Cmet.2015.07.001 |
0.329 |
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2015 |
Sánchez BJ, Nielsen J. Genome scale models of yeast: towards standardized evaluation and consistent omic integration. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 26079294 DOI: 10.1039/C5Ib00083A |
0.393 |
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2015 |
López J, Essus K, Kim IK, Pereira R, Herzog J, Siewers V, Nielsen J, Agosin E. Production of β-ionone by combined expression of carotenogenic and plant CCD1 genes in Saccharomyces cerevisiae. Microbial Cell Factories. 14: 84. PMID 26063466 DOI: 10.1186/S12934-015-0273-X |
0.345 |
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2015 |
Gatto F, Miess H, Schulze A, Nielsen J. Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism. Scientific Reports. 5: 10738. PMID 26040780 DOI: 10.1038/Srep10738 |
0.42 |
|
2015 |
Tymoshenko S, Oppenheim RD, Agren R, Nielsen J, Soldati-Favre D, Hatzimanikatis V. Metabolic Needs and Capabilities of Toxoplasma gondii through Combined Computational and Experimental Analysis. Plos Computational Biology. 11: e1004261. PMID 26001086 DOI: 10.1371/Journal.Pcbi.1004261 |
0.447 |
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2015 |
Väremo L, Scheele C, Broholm C, Mardinoglu A, Kampf C, Asplund A, Nookaew I, Uhlén M, Pedersen BK, Nielsen J. Proteome- and transcriptome-driven reconstruction of the human myocyte metabolic network and its use for identification of markers for diabetes. Cell Reports. 11: 921-33. PMID 25937284 DOI: 10.1016/J.Celrep.2015.04.010 |
0.398 |
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2015 |
Nicastro R, Tripodi F, Guzzi C, Reghellin V, Khoomrung S, Capusoni C, Compagno C, Airoldi C, Nielsen J, Alberghina L, Coccetti P. Enhanced amino acid utilization sustains growth of cells lacking Snf1/AMPK. Biochimica Et Biophysica Acta. 1853: 1615-25. PMID 25841981 DOI: 10.1016/J.Bbamcr.2015.03.014 |
0.39 |
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2015 |
Pronk JT, Lee SY, Lievense J, Pierce J, Palsson B, Uhlen M, Nielsen J. How to set up collaborations between academia and industrial biotech companies. Nature Biotechnology. 33: 237-40. PMID 25748909 DOI: 10.1038/Nbt.3171 |
0.4 |
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2015 |
Zhang C, Ji B, Mardinoglu A, Nielsen J, Hua Q. Logical transformation of genome-scale metabolic models for gene level applications and analysis. Bioinformatics (Oxford, England). PMID 25735769 DOI: 10.1093/Bioinformatics/Btv134 |
0.359 |
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2015 |
Jullesson D, David F, Pfleger B, Nielsen J. Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals. Biotechnology Advances. PMID 25728067 DOI: 10.1016/J.Biotechadv.2015.02.011 |
0.38 |
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2015 |
Pfleger BF, Gossing M, Nielsen J. Metabolic engineering strategies for microbial synthesis of oleochemicals. Metabolic Engineering. 29: 1-11. PMID 25662836 DOI: 10.1016/J.Ymben.2015.01.009 |
0.388 |
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2015 |
Ghaffari P, Mardinoglu A, Asplund A, Shoaie S, Kampf C, Uhlen M, Nielsen J. Identifying anti-growth factors for human cancer cell lines through genome-scale metabolic modeling Scientific Reports. 5: 8183-8183. PMID 25640694 DOI: 10.1038/Srep08183 |
0.336 |
|
2015 |
Buijs NA, Zhou YJ, Siewers V, Nielsen J. Long‐chain alkane production by the yeast Saccharomyces cerevisiae Biotechnology and Bioengineering. 112: 1275-1279. PMID 25545362 DOI: 10.1002/Bit.25522 |
0.342 |
|
2015 |
Krivoruchko A, Nielsen J. Production of natural products through metabolic engineering of Saccharomyces cerevisiae. Current Opinion in Biotechnology. 35: 7-15. PMID 25544013 DOI: 10.1016/j.copbio.2014.12.004 |
0.322 |
|
2015 |
Krivoruchko A, Zhang Y, Siewers V, Chen Y, Nielsen J. Microbial acetyl-CoA metabolism and metabolic engineering. Metabolic Engineering. 28: 28-42. PMID 25485951 DOI: 10.1016/j.ymben.2014.11.009 |
0.327 |
|
2015 |
Borodina I, Kildegaard KR, Jensen NB, Blicher TH, Maury J, Sherstyk S, Schneider K, Lamosa P, Herrgård MJ, Rosenstand I, Öberg F, Forster J, Nielsen J. Establishing a synthetic pathway for high-level production of 3-hydroxypropionic acid in Saccharomyces cerevisiae via β-alanine. Metabolic Engineering. 27: 57-64. PMID 25447643 DOI: 10.1016/J.Ymben.2014.10.003 |
0.695 |
|
2015 |
Martínez JL, Liu L, Petranovic D, Nielsen J. Engineering the oxygen sensing regulation results in an enhanced recombinant human hemoglobin production by Saccharomyces cerevisiae. Biotechnology and Bioengineering. 112: 181-8. PMID 25082441 DOI: 10.1002/Bit.25347 |
0.362 |
|
2015 |
Kildegaard KR, Wang Z, Chen Y, Nielsen J, Borodina I. Production of 3-hydroxypropionic acid from glucose and xylose by metabolically engineered Saccharomyces cerevisiae Metabolic Engineering Communications. 2: 132-136. DOI: 10.1016/J.Meteno.2015.10.001 |
0.386 |
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2014 |
Aspuria PJ, Lunt SY, Väremo L, Vergnes L, Gozo M, Beach JA, Salumbides B, Reue K, Wiedemeyer WR, Nielsen J, Karlan BY, Orsulic S. Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism. Cancer & Metabolism. 2: 21. PMID 25671108 DOI: 10.1186/2049-3002-2-21 |
0.372 |
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2014 |
Chen Y, Zhou YJ, Siewers V, Nielsen J. Enabling Technologies to Advance Microbial Isoprenoid Production Advances in Biochemical Engineering \/ Biotechnology. 148: 143-160. PMID 25549781 DOI: 10.1007/10_2014_284 |
0.351 |
|
2014 |
Nielsen J. Synthetic biology for engineering acetyl coenzyme A metabolism in yeast. Mbio. 5: e02153. PMID 25370498 DOI: 10.1128/mBio.02153-14 |
0.307 |
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2014 |
Caspeta L, Chen Y, Ghiaci P, Feizi A, Buskov S, Hallström BM, Petranovic D, Nielsen J. Altered sterol composition renders yeast thermotolerant Science. 346: 75-78. PMID 25278608 DOI: 10.1126/Science.1258137 |
0.365 |
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2014 |
Kildegaard KR, Hallström BM, Blicher TH, Sonnenschein N, Jensen NB, Sherstyk S, Harrison SJ, Maury J, Herrgård MJ, Juncker AS, Forster J, Nielsen J, Borodina I. Evolution reveals a glutathione-dependent mechanism of 3-hydroxypropionic acid tolerance. Metabolic Engineering. 26: 57-66. PMID 25263954 DOI: 10.1016/J.Ymben.2014.09.004 |
0.691 |
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2014 |
Fahnøe U, Pedersen AG, Risager PC, Nielsen J, Belsham GJ, Höper D, Beer M, Rasmussen TB. Rescue of the highly virulent classical swine fever virus strain "Koslov" from cloned cDNA and first insights into genome variations relevant for virulence Virology. 468: 379-387. PMID 25240324 DOI: 10.1016/J.Virol.2014.08.021 |
0.306 |
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2014 |
Zhou YJ, Buijs NA, Siewers V, Nielsen J. Fatty Acid-Derived Biofuels and Chemicals Production in Saccharomyces cerevisiae Frontiers in Bioengineering and Biotechnology. 2: 32-32. PMID 25225637 DOI: 10.3389/Fbioe.2014.00032 |
0.37 |
|
2014 |
Kampf C, Mardinoglu A, Fagerberg L, Hallström BM, Danielsson A, Nielsen J, Pontén F, Uhlen M. Defining the human gallbladder proteome by transcriptomics and affinity proteomics. Proteomics. 14: 2498-2507. PMID 25175928 DOI: 10.1002/Pmic.201400201 |
0.334 |
|
2014 |
Kerkhoven EJ, Lahtvee P, Nielsen J. Applications of computational modeling in metabolic engineering of yeast Fems Yeast Research. 15: 1-13. PMID 25156867 DOI: 10.1111/1567-1364.12199 |
0.423 |
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2014 |
Liu Z, Liu L, Österlund T, Hou J, Huang M, Fagerberg L, Petranovic D, Uhlén M, Nielsen J. Improved production of a heterologous amylase in Saccharomyces cerevisiae by inverse metabolic engineering. Applied and Environmental Microbiology. 80: 5542-50. PMID 24973076 DOI: 10.1128/Aem.00712-14 |
0.409 |
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2014 |
Liu L, Feizi A, Österlund T, Hjort C, Nielsen J. Genome-scale analysis of the high-efficient protein secretion system of Aspergillus oryzae Bmc Systems Biology. 8: 73-73. PMID 24961398 DOI: 10.1186/1752-0509-8-73 |
0.332 |
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2014 |
Tyo KE, Liu Z, Magnusson Y, Petranovic D, Nielsen J. Impact of protein uptake and degradation on recombinant protein secretion in yeast. Applied Microbiology and Biotechnology. 98: 7149-59. PMID 24816620 DOI: 10.1007/S00253-014-5783-7 |
0.319 |
|
2014 |
Shi S, Chen Y, Siewers V, Nielsen J. Improving Production of Malonyl Coenzyme A-Derived Metabolites by Abolishing Snf1-Dependent Regulation of Acc1 Mbio. 5. PMID 24803522 DOI: 10.1128/Mbio.01130-14 |
0.372 |
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2014 |
Shi S, Valle-Rodríguez JO, Siewers V, Nielsen J. Engineering of chromosomal wax ester synthase integrated Saccharomyces cerevisiae mutants for improved biosynthesis of fatty acid ethyl esters Biotechnology and Bioengineering. 111: 1740-1747. PMID 24752598 DOI: 10.1002/Bit.25234 |
0.401 |
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2014 |
Almquist J, Cvijovic M, Hatzimanikatis V, Nielsen J, Jirstrand M. Kinetic models in industrial biotechnology - Improving cell factory performance. Metabolic Engineering. 24: 38-60. PMID 24747045 DOI: 10.1016/J.Ymben.2014.03.007 |
0.325 |
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2014 |
Nielsen J, Fussenegger M, Keasling J, Lee SY, Liao JC, Prather K, Palsson B. Engineering synergy in biotechnology. Nature Chemical Biology. 10: 319-22. PMID 24743245 DOI: 10.1038/Nchembio.1519 |
0.491 |
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2014 |
El-Semman IE, Karlsson FH, Shoaie S, Nookaew I, Soliman TH, Nielsen J. Genome-scale metabolic reconstructions of Bifidobacterium adolescentis L2-32 and Faecalibacterium prausnitzii A2-165 and their interaction Bmc Systems Biology. 8: 41-41. PMID 24708835 DOI: 10.1186/1752-0509-8-41 |
0.374 |
|
2014 |
Borodina I, Nielsen J. Advances in metabolic engineering of yeast Saccharomyces cerevisiae for production of chemicals. Biotechnology Journal. 9: 609-620. PMID 24677744 DOI: 10.1002/Biot.201300445 |
0.4 |
|
2014 |
Martínez JL, Bordel S, Hong KK, Nielsen J. Gcn4p and the Crabtree effect of yeast: drawing the causal model of the Crabtree effect in Saccharomyces cerevisiae and explaining evolutionary trade-offs of adaptation to galactose through systems biology. Fems Yeast Research. 14: 654-62. PMID 24655306 DOI: 10.1111/1567-1364.12153 |
0.328 |
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2014 |
Agren R, Mardinoglu A, Asplund A, Kampf C, Uhlen M, Nielsen J. Identification of anticancer drugs for hepatocellular carcinoma through personalized genome-scale metabolic modeling Molecular Systems Biology. 10: 721-721. PMID 24646661 DOI: 10.1002/Msb.145122 |
0.307 |
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2014 |
Chumnanpuen P, Hansen MAE, Smedsgaard J, Nielsen J. Dynamic Metabolic Footprinting Reveals the Key Components of Metabolic Network in Yeast Saccharomyces cerevisiae. Comparative and Functional Genomics. 2014: 894296-894296. PMID 24616891 DOI: 10.1155/2014/894296 |
0.388 |
|
2014 |
Mardinoglu A, Agren R, Kampf C, Asplund A, Uhlen M, Nielsen J. Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease Nature Communications. 5: 3083-3083. PMID 24419221 DOI: 10.1038/Ncomms4083 |
0.323 |
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2014 |
Ledesma-Amaro R, Kerkhoven EJ, Revuelta JL, Nielsen J. Genome Scale Metabolic Modeling of the Riboflavin Overproducer Ashbya gossypii Biotechnology and Bioengineering. 111: 1191-1199. PMID 24374726 DOI: 10.1002/Bit.25167 |
0.432 |
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2014 |
Sjostrom SL, Bai Y, Huang M, Liu Z, Nielsen J, Joensson HN, Svahn HA. High-throughput screening for industrial enzyme production hosts by droplet microfluidics Lab On a Chip. 14: 806-813. PMID 24366236 DOI: 10.1039/C3Lc51202A |
0.347 |
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2014 |
Liu L, Martínez JL, Liu Z, Petranovic D, Nielsen J. Balanced globin protein expression and heme biosynthesis improve production of human hemoglobin in Saccharomyces cerevisiae. Metabolic Engineering. 21: 9-16. PMID 24188961 DOI: 10.1016/J.Ymben.2013.10.010 |
0.36 |
|
2014 |
Jensen NB, Strucko T, Kildegaard KR, David F, Maury J, Mortensen UH, Forster J, Nielsen J, Borodina I. EasyClone: method for iterative chromosomal integration of multiple genes in Saccharomyces cerevisiae. Fems Yeast Research. 14: 238-48. PMID 24151867 DOI: 10.1111/1567-1364.12118 |
0.676 |
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2014 |
Huang M, Bao J, Nielsen J. Biopharmaceutical protein production by Saccharomyces cerevisiae: current state and future prospects Pharmaceutical Bioprocessing. 2: 167-182. DOI: 10.4155/Pbp.14.8 |
0.331 |
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2014 |
Tippmann S, Khoomrung S, Siewers V, Nielsen J. Metabolic Engineering of Saccharomyces cerevisiae for Isoprenoid Production New Biotechnology. 31. DOI: 10.1016/J.Nbt.2014.05.2032 |
0.382 |
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2014 |
Prado AR, Kildegaard K, Li M, Borodina I, Nielsen J. Development of a yeast cell factory for production of aromatic products New Biotechnology. 31: 130. DOI: 10.1016/J.Nbt.2014.05.1934 |
0.302 |
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2014 |
Mardinoglu A, Uhlen M, Nielsen J. The use of Genome-scale metabolic models for drug target and biomarker identification New Biotechnology. 31: 49. DOI: 10.1016/J.Nbt.2014.05.1724 |
0.332 |
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2014 |
Valle-Rodríguez JO, Shi S, Siewers V, Nielsen J. Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid ethyl esters, an advanced biofuel, by eliminating non-essential fatty acid utilization pathways Applied Energy. 115: 226-232. DOI: 10.1016/J.Apenergy.2013.10.003 |
0.388 |
|
2013 |
Jewett MC, Workman CT, Nookaew I, Pizarro FA, Agosin E, Hellgren LI, Nielsen J. Mapping condition-dependent regulation of lipid metabolism in Saccharomyces cerevisiae. G3 (Bethesda, Md.). 3: 1979-95. PMID 24062529 DOI: 10.1534/G3.113.006601 |
0.382 |
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2013 |
Anfelt J, Hallström B, Nielsen J, Uhlén M, Hudson EP. Using transcriptomics to improve butanol tolerance of Synechocystis sp. strain PCC 6803. Applied and Environmental Microbiology. 79: 7419-27. PMID 24056459 DOI: 10.1128/Aem.02694-13 |
0.383 |
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2013 |
Shoaie S, Karlsson F, Mardinoglu A, Nookaew I, Bordel S, Nielsen J. Understanding the interactions between bacteria in the human gut through metabolic modeling Scientific Reports. 3: 2532-2532. PMID 23982459 DOI: 10.1038/Srep02532 |
0.341 |
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2013 |
Petelenz-Kurdziel E, Kuehn C, Nordlander B, Klein D, Hong KK, Jacobson T, Dahl P, Schaber J, Nielsen J, Hohmann S, Klipp E. Quantitative analysis of glycerol accumulation, glycolysis and growth under hyper osmotic stress. Plos Computational Biology. 9: e1003084. PMID 23762021 DOI: 10.1371/journal.pcbi.1003084 |
0.334 |
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2013 |
Krivoruchko A, Serrano-Amatriain C, Chen Y, Siewers V, Nielsen J. Improving biobutanol production in engineered Saccharomyces cerevisiae by manipulation of acetyl-CoA metabolism. Journal of Industrial Microbiology & Biotechnology. 40: 1051-6. PMID 23760499 DOI: 10.1007/s10295-013-1296-0 |
0.303 |
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2013 |
Feizi A, Österlund T, Petranovic D, Bordel S, Nielsen J. Genome-Scale Modeling of the Protein Secretory Machinery in Yeast Plos One. 8. PMID 23667601 DOI: 10.1371/Journal.Pone.0063284 |
0.311 |
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2013 |
Österlund T, Nookaew I, Bordel S, Nielsen J. Mapping condition-dependent regulation of metabolism in yeast through genome-scale modeling Bmc Systems Biology. 7: 36-36. PMID 23631471 DOI: 10.1186/1752-0509-7-36 |
0.466 |
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2013 |
Buijs NA, Siewers V, Nielsen J. Advanced biofuel production by the yeast Saccharomyces cerevisiae Current Opinion in Chemical Biology. 17: 480-488. PMID 23628723 DOI: 10.1016/J.Cbpa.2013.03.036 |
0.328 |
|
2013 |
Mardinoglu A, Gatto F, Nielsen J. Genome-scale modeling of human metabolism - a systems biology approach. Biotechnology Journal. 8: 985-96. PMID 23613448 DOI: 10.1002/biot.201200275 |
0.333 |
|
2013 |
Nielsen J, Larsson C, Maris Av, Pronk J. Metabolic engineering of yeast for production of fuels and chemicals Current Opinion in Biotechnology. 24: 398-404. PMID 23611565 DOI: 10.1016/J.Copbio.2013.03.023 |
0.401 |
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2013 |
Agren R, Otero JM, Nielsen J. Genome-scale modeling enables metabolic engineering of Saccharomyces cerevisiae for succinic acid production. Journal of Industrial Microbiology & Biotechnology. 40: 735-47. PMID 23608777 DOI: 10.1007/s10295-013-1269-3 |
0.34 |
|
2013 |
Caspeta L, Nielsen J. Toward systems metabolic engineering of Aspergillus and Pichia species for the production of chemicals and biofuels. Biotechnology Journal. 8: 534-44. PMID 23576362 DOI: 10.1002/biot.201200345 |
0.33 |
|
2013 |
Agren R, Liu L, Shoaie S, Vongsangnak W, Nookaew I, Nielsen J. The RAVEN toolbox and its use for generating a genome-scale metabolic model for Penicillium chrysogenum. Plos Computational Biology. 9: e1002980. PMID 23555215 DOI: 10.1371/journal.pcbi.1002980 |
0.35 |
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2013 |
Mardinoglu A, Agren R, Kampf C, Asplund A, Nookaew I, Jacobson P, Walley AJ, Froguel P, Carlsson LM, Uhlen M, Nielsen J. Integration of clinical data with a genome-scale metabolic model of the human adipocyte. Molecular Systems Biology. 9: 649. PMID 23511207 DOI: 10.1038/Msb.2013.5 |
0.398 |
|
2013 |
Borgos SEF, Bordel S, Sletta H, Ertesvåg H, Jakobsen ØM, Bruheim P, Ellingsen TE, Nielsen J, Valla S. Mapping global effects of the anti-sigma factor MucA in Pseudomonas fluorescens SBW25 through genome-scale metabolic modeling Bmc Systems Biology. 7: 19-19. PMID 23497367 DOI: 10.1186/1752-0509-7-19 |
0.436 |
|
2013 |
Kocharin K, Siewers V, Nielsen J. Improved polyhydroxybutyrate production by Saccharomyces cerevisiae through the use of the phosphoketolase pathway. Biotechnology and Bioengineering. 110: 2216-24. PMID 23456608 DOI: 10.1002/bit.24888 |
0.334 |
|
2013 |
Thiele I, Swainston N, Fleming RM, Hoppe A, Sahoo S, Aurich MK, Haraldsdottir H, Mo ML, Rolfsson O, Stobbe MD, Thorleifsson SG, Agren R, Bölling C, Bordel S, Chavali AK, ... ... Nielsen J, et al. A community-driven global reconstruction of human metabolism. Nature Biotechnology. 31: 419-25. PMID 23455439 DOI: 10.1038/Nbt.2488 |
0.376 |
|
2013 |
Liu Z, Hou J, Martínez JL, Petranovic D, Nielsen J. Correlation of cell growth and heterologous protein production by Saccharomyces cerevisiae. Applied Microbiology and Biotechnology. 97: 8955-62. PMID 23392765 DOI: 10.1007/S00253-013-4715-2 |
0.353 |
|
2013 |
Otero JM, Cimini D, Patil KR, Poulsen SG, Olsson L, Nielsen J. Industrial systems biology of Saccharomyces cerevisiae enables novel succinic acid cell factory. Plos One. 8: e54144. PMID 23349810 DOI: 10.1371/Journal.Pone.0054144 |
0.458 |
|
2013 |
Chen Y, Daviet L, Schalk M, Siewers V, Nielsen J. Establishing a platform cell factory through engineering of yeast acetyl-CoA metabolism Metabolic Engineering. 15: 48-54. PMID 23164578 DOI: 10.1016/J.Ymben.2012.11.002 |
0.373 |
|
2013 |
Garcia-Albornoz MA, Nielsen J. Application of genome-scale metabolic models in metabolic engineering Industrial Biotechnology. 9: 203-214. DOI: 10.1089/Ind.2013.0011 |
0.411 |
|
2012 |
Partow S, Siewers V, Daviet L, Schalk M, Nielsen J. Reconstruction and Evaluation of the Synthetic Bacterial MEP Pathway in Saccharomyces cerevisiae Plos One. 7. PMID 23285068 DOI: 10.1371/Journal.Pone.0052498 |
0.385 |
|
2012 |
Michener JK, Nielsen J, Smolke CD. Identification and treatment of heme depletion attributed to overexpression of a lineage of evolved P450 monooxygenases. Proceedings of the National Academy of Sciences of the United States of America. 109: 19504-9. PMID 23129650 DOI: 10.1073/Pnas.1212287109 |
0.322 |
|
2012 |
Papini M, Nookaew I, Uhlén M, Nielsen J. Scheffersomyces stipitis : a comparative systems biology study with the Crabtree positive yeast Saccharomyces cerevisiae Microbial Cell Factories. 11: 136-136. PMID 23043429 DOI: 10.1186/1475-2859-11-136 |
0.395 |
|
2012 |
Kocharin K, Chen Y, Siewers V, Nielsen J. Engineering of acetyl-CoA metabolism for the improved production of polyhydroxybutyrate in Saccharomyces cerevisiae. Amb Express. 2: 52. PMID 23009357 DOI: 10.1186/2191-0855-2-52 |
0.33 |
|
2012 |
Nookaew I, Papini M, Pornputtapong N, Scalcinati G, Fagerberg L, Uhlén M, Nielsen J. A comprehensive comparison of RNA-Seq-based transcriptome analysis from reads to differential gene expression and cross-comparison with microarrays: a case study in Saccharomyces cerevisiae Nucleic Acids Research. 40: 10084-10097. PMID 22965124 DOI: 10.1093/Nar/Gks804 |
0.307 |
|
2012 |
Scalcinati G, Partow S, Siewers V, Schalk M, Daviet L, Nielsen J. Combined metabolic engineering of precursor and co-factor supply to increase α-santalene production by Saccharomyces cerevisiae Microbial Cell Factories. 11: 117-117. PMID 22938570 DOI: 10.1186/1475-2859-11-117 |
0.399 |
|
2012 |
Knuf C, Nielsen J. Aspergilli: systems biology and industrial applications. Biotechnology Journal. 7: 1147-55. PMID 22890866 DOI: 10.1002/biot.201200169 |
0.307 |
|
2012 |
Agren R, Bordel S, Mardinoglu A, Pornputtapong N, Nookaew I, Nielsen J. Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT. Plos Computational Biology. 8: e1002518. PMID 22615553 DOI: 10.1371/Journal.Pcbi.1002518 |
0.387 |
|
2012 |
Hou J, Tyo KE, Liu Z, Petranovic D, Nielsen J. Metabolic engineering of recombinant protein secretion by Saccharomyces cerevisiae. Fems Yeast Research. 12: 491-510. PMID 22533807 DOI: 10.1111/J.1567-1364.2012.00810.X |
0.387 |
|
2012 |
Martínez JL, Liu L, Petranovic D, Nielsen J. Pharmaceutical protein production by yeast: towards production of human blood proteins by microbial fermentation. Current Opinion in Biotechnology. 23: 965-71. PMID 22503236 DOI: 10.1016/J.Copbio.2012.03.011 |
0.35 |
|
2012 |
Scalcinati G, Otero JM, Van Vleet JR, Jeffries TW, Olsson L, Nielsen J. Evolutionary engineering of Saccharomyces cerevisiae for efficient aerobic xylose consumption. Fems Yeast Research. 12: 582-97. PMID 22487265 DOI: 10.1111/J.1567-1364.2012.00808.X |
0.44 |
|
2012 |
Caspeta L, Shoaie S, Agren R, Nookaew I, Nielsen J. Genome-scale metabolic reconstructions of Pichia stipitis and Pichia pastoris and in silico evaluation of their potentials. Bmc Systems Biology. 6: 24. PMID 22472172 DOI: 10.1186/1752-0509-6-24 |
0.324 |
|
2012 |
Nijkamp JF, van den Broek M, Datema E, de Kok S, Bosman L, Luttik MA, Daran-Lapujade P, Vongsangnak W, Nielsen J, Heijne WH, Klaassen P, Paddon CJ, Platt D, Kötter P, van Ham RC, et al. De novo sequencing, assembly and analysis of the genome of the laboratory strain Saccharomyces cerevisiae CEN.PK113-7D, a model for modern industrial biotechnology. Microbial Cell Factories. 11: 36. PMID 22448915 DOI: 10.1186/1475-2859-11-36 |
0.351 |
|
2012 |
Tyo KEJ, Liu Z, Petranovic D, Nielsen J. Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress Bmc Biology. 10: 16-16. PMID 22380681 DOI: 10.1186/1741-7007-10-16 |
0.335 |
|
2012 |
Papini M, Nookaew I, Siewers V, Nielsen J. Physiological characterization of recombinant Saccharomyces cerevisiae expressing the Aspergillus nidulans phosphoketolase pathway: validation of activity through 13C-based metabolic flux analysis. Applied Microbiology and Biotechnology. 95: 1001-10. PMID 22367611 DOI: 10.1007/s00253-012-3936-0 |
0.358 |
|
2012 |
Shi S, Valle-Rodríguez JO, Khoomrung S, Siewers V, Nielsen J. Functional expression and characterization of five wax ester synthases in Saccharomyces cerevisiae and their utility for biodiesel production Biotechnology For Biofuels. 5: 7-7. PMID 22364438 DOI: 10.1186/1754-6834-5-7 |
0.361 |
|
2012 |
Scalcinati G, Knuf C, Partow S, Chen Y, Maury J, Schalk M, Daviet L, Nielsen J, Siewers V. Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene α-santalene in a fed-batch mode. Metabolic Engineering. 14: 91-103. PMID 22330799 DOI: 10.1016/J.Ymben.2012.01.007 |
0.389 |
|
2012 |
Vongsangnak W, Figueiredo LF, Förster J, Weber T, Thykaer J, Stegmann E, Wohlleben W, Nielsen J. Genome-scale metabolic representation of Amycolatopsis balhimycina. Biotechnology and Bioengineering. 109: 1798-807. PMID 22252737 DOI: 10.1002/Bit.24436 |
0.738 |
|
2012 |
Nielsen J, Pronk JT. Metabolic engineering, synthetic biology and systems biology. Fems Yeast Research. 12: 103-103. PMID 22188459 DOI: 10.1111/J.1567-1364.2011.00783.X |
0.318 |
|
2012 |
Liu Z, Tyo KE, Martínez JL, Petranovic D, Nielsen J. Different expression systems for production of recombinant proteins in Saccharomyces cerevisiae. Biotechnology and Bioengineering. 109: 1259-68. PMID 22179756 DOI: 10.1002/Bit.24409 |
0.328 |
|
2012 |
Jensen NB, Maury J, Oberg F, Kildegaard KR, Forster J, Nielsen J, Borodina I. Metabolic engineering of Saccharomyces cerevisiae for optimizing 3HP production New Biotechnology. 29. DOI: 10.1016/J.Nbt.2012.08.170 |
0.7 |
|
2011 |
Zhang J, Vaga S, Chumnanpuen P, Kumar R, Vemuri GN, Aebersold R, Nielsen J. Mapping the interaction of Snf1 with TORC1 in Saccharomyces cerevisiae. Molecular Systems Biology. 7: 545. PMID 22068328 DOI: 10.1038/Msb.2011.80 |
0.384 |
|
2011 |
Nookaew I, Olivares-Hernández R, Bhumiratana S, Nielsen J. Genome-scale metabolic models of Saccharomyces cerevisiae. Methods in Molecular Biology (Clifton, N.J.). 759: 445-63. PMID 21863502 DOI: 10.1007/978-1-61779-173-4_25 |
0.409 |
|
2011 |
Osterlund T, Nookaew I, Nielsen J. Fifteen years of large scale metabolic modeling of yeast: developments and impacts. Biotechnology Advances. 30: 979-88. PMID 21846501 DOI: 10.1016/j.biotechadv.2011.07.021 |
0.348 |
|
2011 |
Nielsen J, Keasling JD. Synergies between synthetic biology and metabolic engineering. Nature Biotechnology. 29: 693-5. PMID 21822239 DOI: 10.1038/Nbt.1937 |
0.353 |
|
2011 |
Rokem JS, Vongsangnak W, Nielsen J. Comparative metabolic capabilities for Micrococcus luteus NCTC 2665, the "Fleming" strain, and actinobacteria. Biotechnology and Bioengineering. 108: 2770-5. PMID 21618466 DOI: 10.1002/Bit.23212 |
0.423 |
|
2011 |
RodrÃguez-Limas WA, Tyo KE, Nielsen J, RamÃrez OT, Palomares LA. Molecular and process design for rotavirus-like particle production in Saccharomyces cerevisiae. Microbial Cell Factories. 10: 33. PMID 21569612 DOI: 10.1186/1475-2859-10-33 |
0.329 |
|
2011 |
Andersen MR, Salazar MP, Schaap PJ, van de Vondervoort PJ, Culley D, Thykaer J, Frisvad JC, Nielsen KF, Albang R, Albermann K, Berka RM, Braus GH, Braus-Stromeyer SA, Corrochano LM, Dai Z, ... ... Nielsen JB, ... ... Nielsen J, et al. Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015 versus enzyme-producing CBS 513.88. Genome Research. 21: 885-97. PMID 21543515 DOI: 10.1101/Gr.112169.110 |
0.373 |
|
2011 |
Piddocke MP, Fazio A, Vongsangnak W, Wong ML, Heldt-Hansen HP, Workman C, Nielsen J, Olsson L. Revealing the beneficial effect of protease supplementation to high gravity beer fermentations using "-omics" techniques. Microbial Cell Factories. 10: 27. PMID 21513553 DOI: 10.1186/1475-2859-10-27 |
0.389 |
|
2011 |
Vongsangnak W, Hansen K, Nielsen J. Integrated analysis of the global transcriptional response to α‐amylase over‐production by Aspergillus oryzae Biotechnology and Bioengineering. 108: 1130-1139. PMID 21449027 DOI: 10.1002/Bit.23033 |
0.4 |
|
2011 |
Madsen KM, Udatha GD, Semba S, Otero JM, Koetter P, Nielsen J, Ebizuka Y, Kushiro T, Panagiotou G. Linking genotype and phenotype of Saccharomyces cerevisiae strains reveals metabolic engineering targets and leads to triterpene hyper-producers. Plos One. 6: e14763. PMID 21445244 DOI: 10.1371/Journal.Pone.0014763 |
0.652 |
|
2011 |
Hansen BG, Salomonsen B, Nielsen MT, Nielsen JB, Hansen NB, Nielsen KF, Regueira TB, Nielsen J, Patil KR, Mortensen UH. Versatile enzyme expression and characterization system for Aspergillus nidulans, with the Penicillium brevicompactum polyketide synthase gene from the mycophenolic acid gene cluster as a test case. Applied and Environmental Microbiology. 77: 3044-51. PMID 21398493 DOI: 10.1128/Aem.01768-10 |
0.347 |
|
2011 |
Regueira TB, Kildegaard KR, Hansen BG, Mortensen UH, Hertweck C, Nielsen J. Molecular basis for mycophenolic acid biosynthesis in Penicillium brevicompactum. Applied and Environmental Microbiology. 77: 3035-43. PMID 21398490 DOI: 10.1128/Aem.03015-10 |
0.359 |
|
2011 |
Cvijovic M, Bordel S, Nielsen J. Mathematical models of cell factories: moving towards the core of industrial biotechnology. Microbial Biotechnology. 4: 572-584. PMID 21375719 DOI: 10.1111/J.1751-7915.2010.00233.X |
0.355 |
|
2011 |
Van Mulders SE, Stassen C, Daenen L, Devreese B, Siewers V, van Eijsden RG, Nielsen J, Delvaux FR, Willaert R. The influence of microgravity on invasive growth in Saccharomyces cerevisiae. Astrobiology. 11: 45-55. PMID 21345087 DOI: 10.1089/Ast.2010.0518 |
0.306 |
|
2011 |
Krivoruchko A, Siewers V, Nielsen J. Opportunities for yeast metabolic engineering: Lessons from synthetic biology. Biotechnology Journal. 6: 262-76. PMID 21328545 DOI: 10.1002/Biot.201000308 |
0.384 |
|
2011 |
Shi S, Valle-Rodríguez JO, Siewers V, Nielsen J. Prospects for microbial biodiesel production Biotechnology Journal. 6: 277-285. PMID 21328544 DOI: 10.1002/Biot.201000117 |
0.313 |
|
2011 |
Pabinger S, Rader R, Agren R, Nielsen J, Trajanoski Z. MEMOSys: Bioinformatics platform for genome-scale metabolic models. Bmc Systems Biology. 5: 20. PMID 21276275 DOI: 10.1186/1752-0509-5-20 |
0.372 |
|
2011 |
Karlsson FH, Ussery DW, Nielsen J, Nookaew I. A closer look at bacteroides: phylogenetic relationship and genomic implications of a life in the human gut. Microbial Ecology. 61: 473-85. PMID 21222211 DOI: 10.1007/S00248-010-9796-1 |
0.316 |
|
2011 |
Ruenwai R, Neiss A, Laoteng K, Vongsangnak W, Dalfard AB, Cheevadhanarak S, Petranovic D, Nielsen J. Heterologous production of polyunsaturated fatty acids in Saccharomyces cerevisiae causes a global transcriptional response resulting in reduced proteasomal activity and increased oxidative stress. Biotechnology Journal. 6: 343-56. PMID 21184438 DOI: 10.1002/Biot.201000316 |
0.338 |
|
2011 |
Albertsen L, Chen Y, Bach LS, Rattleff S, Maury J, Brix S, Nielsen J, Mortensen UH. Diversion of Flux toward Sesquiterpene Production in Saccharomyces cerevisiae by Fusion of Host and Heterologous Enzymes Applied and Environmental Microbiology. 77: 1033-1040. PMID 21148687 DOI: 10.1128/Aem.01361-10 |
0.401 |
|
2010 |
Canelas AB, Harrison N, Fazio A, Zhang J, Pitkänen JP, van den Brink J, Bakker BM, Bogner L, Bouwman J, Castrillo JI, Cankorur A, Chumnanpuen P, Daran-Lapujade P, Dikicioglu D, van Eunen K, ... ... Nielsen J, et al. Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains. Nature Communications. 1: 145. PMID 21266995 DOI: 10.1038/Ncomms1150 |
0.39 |
|
2010 |
Otero JM, Vongsangnak W, Asadollahi MA, Olivares-Hernandes R, Maury J, Farinelli L, Barlocher L, Østerås M, Schalk M, Clark A, Nielsen J. Whole genome sequencing of Saccharomyces cerevisiae: from genotype to phenotype for improved metabolic engineering applications Bmc Genomics. 11: 723-723. PMID 21176163 DOI: 10.1186/1471-2164-11-723 |
0.416 |
|
2010 |
Otero JM, Papadakis MA, Udatha DB, Nielsen J, Panagiotou G. Yeast biological networks unfold the interplay of antioxidants, genome and phenotype, and reveal a novel regulator of the oxidative stress response. Plos One. 5: e13606. PMID 21049050 DOI: 10.1371/Journal.Pone.0013606 |
0.606 |
|
2010 |
Olivares-Hernández R, Sunner H, Frisvad JC, Olsson L, Nielsen J, Panagiotou G. Combining substrate specificity analysis with support vector classifiers reveals feruloyl esterase as a phylogenetically informative protein group. Plos One. 5: e12781. PMID 20877647 DOI: 10.1371/Journal.Pone.0012781 |
0.579 |
|
2010 |
Bordel S, Agren R, Nielsen J. Sampling the Solution Space in Genome-Scale Metabolic Networks Reveals Transcriptional Regulation in Key Enzymes Plos Computational Biology. 6: 16. PMID 20657658 DOI: 10.1371/Journal.Pcbi.1000859 |
0.42 |
|
2010 |
Olivares-Hernández R, Usaite R, Nielsen J. Integrative Analysis Using Proteome and Transcriptome Data From Yeast to Unravel Regulatory Patterns at Post-Transcriptional Level Biotechnology and Bioengineering. 107: 865-875. PMID 20635383 DOI: 10.1002/Bit.22868 |
0.306 |
|
2010 |
Partow S, Siewers V, Bjørn S, Nielsen J, Maury J. Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae Yeast. 27: 955-964. PMID 20625983 DOI: 10.1002/Yea.1806 |
0.317 |
|
2010 |
Thykaer J, Nielsen J, Wohlleben W, Weber T, Gutknecht M, Lantz AE, Stegmann E. Increased glycopeptide production after overexpression of shikimate pathway genes being part of the balhimycin biosynthetic gene cluster. Metabolic Engineering. 12: 455-461. PMID 20570618 DOI: 10.1016/J.Ymben.2010.05.001 |
0.359 |
|
2010 |
Cvijovic M, Olivares-Hernández R, Agren R, Dahr N, Vongsangnak W, Nookaew I, Patil KR, Nielsen J. BioMet Toolbox: genome-wide analysis of metabolism Nucleic Acids Research. 38: 144-149. PMID 20483918 DOI: 10.1093/Nar/Gkq404 |
0.43 |
|
2010 |
Liu L, Agren R, Bordel S, Nielsen J. Use of genome-scale metabolic models for understanding microbial physiology. Febs Letters. 584: 2556-2564. PMID 20420838 DOI: 10.1016/J.Febslet.2010.04.052 |
0.398 |
|
2010 |
Rocha I, Maia P, Evangelista P, Vilaça P, Soares S, Pinto JP, Nielsen J, Patil KR, Ferreira EC, Rocha M. OptFlux: an open-source software platform for in silico metabolic engineering. Bmc Systems Biology. 4: 45. PMID 20403172 DOI: 10.1186/1752-0509-4-45 |
0.351 |
|
2010 |
Bordel S, Nielsen J. Identification of flux control in metabolic networks using non-equilibrium thermodynamics. Metabolic Engineering. 12: 369-77. PMID 20302968 DOI: 10.1016/j.ymben.2010.03.001 |
0.325 |
|
2010 |
Tyo KEJ, Kocharin K, Nielsen J. Toward design-based engineering of industrial microbes Current Opinion in Microbiology. 13: 255-262. PMID 20226723 DOI: 10.1016/J.Mib.2010.02.001 |
0.315 |
|
2010 |
Asadollahi MA, Maury J, Schalk M, Clark A, Nielsen J. Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae Biotechnology and Bioengineering. 106: 86-96. PMID 20091767 DOI: 10.1002/Bit.22668 |
0.422 |
|
2010 |
Otero JM, Nielsen J. Industrial systems biology. Biotechnology and Bioengineering. 105: 439-60. PMID 19891008 DOI: 10.1002/bit.22592 |
0.332 |
|
2009 |
Usaite R, Jewett MC, Oliveira AP, Yates JR, Olsson L, Nielsen J. Reconstruction of the yeast Snf1 kinase regulatory network reveals its role as a global energy regulator. Molecular Systems Biology. 5: 319. PMID 19888214 DOI: 10.1038/Msb.2009.67 |
0.37 |
|
2009 |
Salazar M, Vongsangnak W, Panagiotou G, Andersen MR, Nielsen J. Uncovering transcriptional regulation of glycerol metabolism in Aspergilli through genome-wide gene expression data analysis. Molecular Genetics and Genomics : Mgg. 282: 571-86. PMID 19784673 DOI: 10.1007/S00438-009-0486-Y |
0.643 |
|
2009 |
Rossouw D, Olivares-Hernandes R, Nielsen J, Bauer FF. Comparative Transcriptomic Approach To Investigate Differences in Wine Yeast Physiology and Metabolism during Fermentation Applied and Environmental Microbiology. 75: 6600-6612. PMID 19700545 DOI: 10.1128/Aem.01251-09 |
0.365 |
|
2009 |
Vongsangnak W, Salazar M, Hansen K, Nielsen J. Genome-wide analysis of maltose utilization and regulation in aspergilli. Microbiology (Reading, England). 155: 3893-3902. PMID 19696104 DOI: 10.1099/mic.0.031104-0 |
0.365 |
|
2009 |
Siewers V, Chen X, Huang L, Zhang J, Nielsen J. Heterologous production of non-ribosomal peptide LLD-ACV in Saccharomyces cerevisiae Metabolic Engineering. 11: 391-397. PMID 19686863 DOI: 10.1016/J.Ymben.2009.08.002 |
0.352 |
|
2009 |
Flagfeldt DB, Siewers V, Huang L, Nielsen J. Characterization of chromosomal integration sites for heterologous gene expression in Saccharomyces cerevisiae. Yeast. 26: 545-551. PMID 19681174 DOI: 10.1002/Yea.1705 |
0.309 |
|
2009 |
Asadollahi M, Maury J, Patil KR, schalk M, Clark A, Nielsen J. Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering. Metabolic Engineering. 11: 328-334. PMID 19619667 DOI: 10.1016/J.Ymben.2009.07.001 |
0.425 |
|
2009 |
Coutinho PM, Andersen MR, Kolenova K, vanKuyk PA, Benoit I, Gruben BS, Trejo-Aguilar B, Visser H, van Solingen P, Pakula T, Seiboth B, Battaglia E, Aguilar-Osorio G, de Jong JF, Ohm RA, ... ... Nielsen J, et al. Post-genomic insights into the plant polysaccharide degradation potential of Aspergillus nidulans and comparison to Aspergillus niger and Aspergillus oryzae. Fungal Genetics and Biology : Fg & B. 46: S161-S169. PMID 19618505 DOI: 10.1016/J.Fgb.2008.07.020 |
0.324 |
|
2009 |
Panagiotou G, Nielsen J. Nutritional systems biology: definitions and approaches. Annual Review of Nutrition. 29: 329-39. PMID 19575602 DOI: 10.1146/Annurev-Nutr-080508-141138 |
0.624 |
|
2009 |
Meijer S, Nielsen ML, Olsson L, Nielsen J. Gene deletion of cytosolic ATP: citrate lyase leads to altered organic acid production in Aspergillus niger. Journal of Industrial Microbiology & Biotechnology. 36: 1275-80. PMID 19554356 DOI: 10.1007/S10295-009-0607-Y |
0.414 |
|
2009 |
Meijer SL, Jongh WAD, Olsson L, Nielsen J. Physiological characterisation of acuB deletion in Aspergillus niger Applied Microbiology and Biotechnology. 84: 157-167. PMID 19444441 DOI: 10.1007/S00253-009-2027-3 |
0.415 |
|
2009 |
Andersen MR, Lehmann LO, Nielsen J. Systemic analysis of the response of Aspergillus niger to ambient pH Genome Biology. 10: 1-14. PMID 19409083 DOI: 10.1186/Gb-2009-10-5-R47 |
0.327 |
|
2009 |
Diano A, Peeters J, Dynesen J, Nielsen J. Physiology of Aspergillus niger in oxygen-limited continuous cultures: Influence of aeration, carbon source concentration and dilution rate. Biotechnology and Bioengineering. 103: 956-65. PMID 19382249 DOI: 10.1002/Bit.22329 |
0.345 |
|
2009 |
Moxley JF, Jewett MC, Antoniewicz MR, Villas-Boas SG, Alper H, Wheeler RT, Tong L, Hinnebusch AG, Ideker T, Nielsen J, Stephanopoulos G. Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p. Proceedings of the National Academy of Sciences of the United States of America. 106: 6477-82. PMID 19346491 DOI: 10.1073/Pnas.0811091106 |
0.418 |
|
2009 |
Cimini D, Patil KR, Schiraldi C, Nielsen J. Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3 Bmc Systems Biology. 3: 17-17. PMID 19200357 DOI: 10.1186/1752-0509-3-17 |
0.306 |
|
2009 |
Panagiotou G, Andersen MR, Grotkjaer T, Regueira TB, Nielsen J, Olsson L. Studies of the production of fungal polyketides in Aspergillus nidulans by using systems biology tools. Applied and Environmental Microbiology. 75: 2212-20. PMID 19168657 DOI: 10.1128/Aem.01461-08 |
0.668 |
|
2009 |
Wortman JR, Gilsenan JM, Joardar V, Deegan J, Clutterbuck J, Andersen MR, Archer D, Bencina M, Braus G, Coutinho P, von Döhren H, Doonan J, Driessen AJ, Durek P, Espeso E, ... ... Nielsen J, et al. The 2008 update of the Aspergillus nidulans genome annotation: a community effort. Fungal Genetics and Biology : Fg & B. 46: S2-13. PMID 19146970 DOI: 10.1016/J.Fgb.2008.12.003 |
0.319 |
|
2009 |
Christensen TS, Oliveira APSd, Nielsen J. Reconstruction and logical modeling of glucose repression signaling pathways in Saccharomyces cerevisiae Bmc Systems Biology. 3: 7-7. PMID 19144179 DOI: 10.1186/1752-0509-3-7 |
0.324 |
|
2009 |
Kjeldsen KR, Nielsen J. In silico genome-scale reconstruction and validation of the Corynebacterium glutamicum metabolic network. Biotechnology and Bioengineering. 102: 583-597. PMID 18985611 DOI: 10.1002/Bit.22067 |
0.422 |
|
2009 |
Hofmann G, Diano A, Nielsen J. Recombinant bacterial hemoglobin alters metabolism of Aspergillus niger Metabolic Engineering. 11: 8-12. PMID 18694843 DOI: 10.1016/J.Ymben.2008.07.002 |
0.382 |
|
2009 |
Pedersen L, Hansen K, Nielsen KF, Nielsen J, Lantz AE, Thykaer J. In-depth analysis of Aspergillus niger metabolism during industrial fed-batch fermentations New Biotechnology. 25: 210-211. DOI: 10.1016/J.Nbt.2009.06.158 |
0.364 |
|
2008 |
Panagiotou G, Andersen MR, Grotkjaer T, Regueira TB, Hofmann G, Nielsen J, Olsson L. Systems analysis unfolds the relationship between the phosphoketolase pathway and growth in Aspergillus nidulans. Plos One. 3: e3847. PMID 19052639 DOI: 10.1371/Journal.Pone.0003847 |
0.645 |
|
2008 |
Rocha M, Maia P, Mendes R, Pinto JP, Ferreira EC, Nielsen J, Patil KR, Rocha I. Natural computation meta-heuristics for the in silico optimization of microbial strains. Bmc Bioinformatics. 9: 499. PMID 19038030 DOI: 10.1186/1471-2105-9-499 |
0.39 |
|
2008 |
Maury J, Asadollahi MA, Møller K, Schalk M, Clark A, Formenti LR, Nielsen J. Reconstruction of a bacterial isoprenoid biosynthetic pathway in Saccharomyces cerevisiae Febs Letters. 582: 4032-4038. PMID 18996117 DOI: 10.1016/J.Febslet.2008.10.045 |
0.364 |
|
2008 |
Herrgård MJ, Swainston N, Dobson P, Dunn WB, Arga KY, Arvas M, Blüthgen N, Borger S, Costenoble R, Heinemann M, Hucka M, Le Novère N, Li P, Liebermeister W, Mo ML, ... ... Nielsen J, et al. A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology. Nature Biotechnology. 26: 1155-60. PMID 18846089 DOI: 10.1038/Nbt1492 |
0.378 |
|
2008 |
Pizarro FJ, Jewett MC, Nielsen J, Agosin E. Growth temperature exerts differential physiological and transcriptional responses in laboratory and wine strains of Saccharomyces cerevisiae. Applied and Environmental Microbiology. 74: 6358-68. PMID 18723660 DOI: 10.1128/Aem.00602-08 |
0.361 |
|
2008 |
Nookaew I, Jewett MC, Meechai A, Thammarongtham C, Laoteng K, Cheevadhanarak S, Nielsen J, Bhumiratana S. The genome-scale metabolic model iIN800 of Saccharomyces cerevisiae and its validation: a scaffold to query lipid metabolism. Bmc Systems Biology. 2: 71. PMID 18687109 DOI: 10.1186/1752-0509-2-71 |
0.388 |
|
2008 |
Mapelli V, Olsson L, Nielsen J. Metabolic footprinting in microbiology: methods and applications in functional genomics and biotechnology. Trends in Biotechnology. 26: 490-7. PMID 18675480 DOI: 10.1016/j.tibtech.2008.05.008 |
0.34 |
|
2008 |
Fazio A, Jewett MC, Daran-Lapujade P, Mustacchi R, Usaite R, Pronk JT, Workman CT, Nielsen J. Transcription factor control of growth rate dependent genes in Saccharomyces cerevisiae: a three factor design. Bmc Genomics. 9: 341. PMID 18638364 DOI: 10.1186/1471-2164-9-341 |
0.343 |
|
2008 |
Borodina I, Siebring J, Zhang J, Smith CP, van Keulen G, Dijkhuizen L, Nielsen J. Antibiotic overproduction in Streptomyces coelicolor A3 2 mediated by phosphofructokinase deletion. The Journal of Biological Chemistry. 283: 25186-99. PMID 18606812 DOI: 10.1074/Jbc.M803105200 |
0.447 |
|
2008 |
Wattanachaisaereekul S, Lantz AE, Nielsen ML, Nielsen J. Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply. Metabolic Engineering. 10: 246-54. PMID 18555717 DOI: 10.1016/J.Ymben.2008.04.005 |
0.374 |
|
2008 |
Vongsangnak W, Olsen P, Hansen K, Krogsgaard S, Nielsen J. Improved annotation through genome-scale metabolic modeling of Aspergillus oryzae. Bmc Genomics. 9: 245. PMID 18500999 DOI: 10.1186/1471-2164-9-245 |
0.304 |
|
2008 |
David H, Özçelik İŞ, Hofmann G, Nielsen J. Analysis of Aspergillus nidulans metabolism at the genome-scale Bmc Genomics. 9: 163-163. PMID 18405346 DOI: 10.1186/1471-2164-9-163 |
0.347 |
|
2008 |
Rocha I, Förster J, Nielsen J. Design and application of genome-scale reconstructed metabolic models. Methods in Molecular Biology (Clifton, N.J.). 416: 409-31. PMID 18392985 DOI: 10.1007/978-1-59745-321-9_29 |
0.704 |
|
2008 |
Thykaer J, Rueksomtawin K, Noorman H, Nielsen J. NADPH-dependent glutamate dehydrogenase in Penicillium chrysogenum is involved in regulation of β-lactam production Microbiology. 154: 1242-1250. PMID 18375816 DOI: 10.1099/Mic.0.2007/010017-0 |
0.314 |
|
2008 |
Andersen MR, Nielsen ML, Nielsen J. Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger. Molecular Systems Biology. 4: 178. PMID 18364712 DOI: 10.1038/Msb.2008.12 |
0.408 |
|
2008 |
Andersen MR, Vongsangnak W, Panagiotou G, Salazar MP, Lehmann L, Nielsen J. A trispecies Aspergillus microarray: comparative transcriptomics of three Aspergillus species. Proceedings of the National Academy of Sciences of the United States of America. 105: 4387-92. PMID 18332432 DOI: 10.1073/Pnas.0709964105 |
0.615 |
|
2008 |
Jongh WAd, Nielsen J. Enhanced citrate production through gene insertion in Aspergillus niger. Metabolic Engineering. 10: 87-96. PMID 18162426 DOI: 10.1016/J.Ymben.2007.11.002 |
0.355 |
|
2008 |
Nielsen J, Jewett MC. Impact of systems biology on metabolic engineering of Saccharomyces cerevisiae. Fems Yeast Research. 8: 122-31. PMID 17727659 DOI: 10.1111/J.1567-1364.2007.00302.X |
0.392 |
|
2008 |
Asadollahi MA, Maury J, Møller K, Nielsen KF, Schalk M, Clark A, Nielsen J. Production of plant sesquiterpenes in Saccharomyces cerevisiae: Effect of ERG9 repression on sesquiterpene biosynthesis Biotechnology and Bioengineering. 99: 666-677. PMID 17705244 DOI: 10.1002/Bit.21581 |
0.364 |
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2008 |
Prathumpai W, Gabelgaard JB, Wanchanthuek P, Vondervoort PJIvd, Groot MJLd, Mcintyre M, Nielsen J. Metabolic Control Analysis of Xylose Catabolism in Aspergillus Biotechnology Progress. 19: 1136-1141. PMID 12892473 DOI: 10.1021/Bp034020R |
0.371 |
|
2008 |
Penttilä M, Nielsen J, Boekhout T. Yeast systems biology. Fems Yeast Research. 8: 121-121. DOI: 10.1111/J.1567-1364.2007.00346.X |
0.306 |
|
2007 |
van der Werf MJ, Takors R, Smedsgaard J, Nielsen J, Ferenci T, Portais JC, Wittmann C, Hooks M, Tomassini A, Oldiges M, Fostel J, Sauer U. Standard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments. Metabolomics : Official Journal of the Metabolomic Society. 3: 189-194. PMID 25653575 DOI: 10.1007/S11306-007-0080-4 |
0.31 |
|
2007 |
Rokem JS, Lantz AE, Nielsen J. Systems biology of antibiotic production by microorganisms. Natural Product Reports. 24: 1262-87. PMID 18033579 DOI: 10.1039/B617765B |
0.364 |
|
2007 |
Nielsen ML, de Jongh WA, Meijer SL, Nielsen J, Mortensen UH. Transient marker system for iterative gene targeting of a prototrophic fungus. Applied and Environmental Microbiology. 73: 7240-5. PMID 17921280 DOI: 10.1128/Aem.01839-07 |
0.315 |
|
2007 |
Nielsen J. Principles of optimal metabolic network operation Molecular Systems Biology. 3. PMID 17625514 DOI: 10.1038/Msb4100169 |
0.369 |
|
2007 |
Çakır T, Kırdar B, Önsan Zİ, Ülgen KÖ, Nielsen J. Effect of carbon source perturbations on transcriptional regulation of metabolic fluxes in Saccharomyces cerevisiae. Bmc Systems Biology. 1: 18-18. PMID 17408508 DOI: 10.1186/1752-0509-1-18 |
0.368 |
|
2007 |
Meijer SL, Panagiotou G, Olsson L, Nielsen J. Physiological characterization of xylose metabolism in Aspergillus niger under oxygen‐limited conditions Biotechnology and Bioengineering. 98: 462-475. PMID 17335061 DOI: 10.1002/Bit.21397 |
0.647 |
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2007 |
Vemuri GN, Eiteman MA, McEwen JE, Olsson L, Nielsen J. Increasing NADH oxidation reduces overflow metabolism in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 104: 2402-2407. PMID 17287356 DOI: 10.1073/Pnas.0607469104 |
0.389 |
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2007 |
Pel HJ, de Winde JH, Archer DB, Dyer PS, Hofmann G, Schaap PJ, Turner G, de Vries RP, Albang R, Albermann K, Andersen MR, Bendtsen JD, Benen JA, van den Berg M, Breestraat S, ... ... Nielsen J, et al. Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88. Nature Biotechnology. 25: 221-31. PMID 17259976 DOI: 10.1038/Nbt1282 |
0.407 |
|
2007 |
Arga KY, Onsan ZI, Kirdar B, Ulgen KO, Nielsen J. Understanding signaling in yeast: Insights from network analysis. Biotechnology and Bioengineering. 97: 1246-1258. PMID 17252576 DOI: 10.1002/Bit.21317 |
0.314 |
|
2007 |
Nookaew I, Meechai A, Thammarongtham C, Laoteng K, Ruanglek V, Cheevadhanarak S, Nielsen J, Bhumiratana S. Identification of flux regulation coefficients from elementary flux modes: A systems biology tool for analysis of metabolic networks. Biotechnology and Bioengineering. 97: 1535-49. PMID 17238207 DOI: 10.1002/Bit.21339 |
0.351 |
|
2007 |
Højer-Pedersen J, Smedsgaard J, Nielsen J. Elucidating the mode-of-action of compounds from metabolite profiling studies Progress in Drug Research. 64: 103-129. PMID 17195473 DOI: 10.1007/978-3-7643-7567-6_5 |
0.334 |
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2007 |
Wattanachaisaereekul S, Lantz AE, Nielsen ML, Andrésson OS, Nielsen J. Optimization of heterologous production of the polyketide 6-MSA in Saccharomyces cerevisiae. Biotechnology and Bioengineering. 97: 893-900. PMID 17171715 DOI: 10.1002/Bit.21286 |
0.386 |
|
2007 |
Baxter CJ, Redestig H, Schauer N, Repsilber D, Patil KR, Nielsen J, Selbig J, Liu J, Fernie AR, Sweetlove LJ. The metabolic response of heterotrophic Arabidopsis cells to oxidative stress. Plant Physiology. 143: 312-25. PMID 17122072 DOI: 10.1104/Pp.106.090431 |
0.372 |
|
2007 |
Mas S, Villas-Bôas SG, Hansen ME, Åkesson M, Nielsen J. A comparison of direct infusion MS and GC-MS for metabolic footprinting of yeast mutants. Biotechnology and Bioengineering. 96: 1014-1022. PMID 17022091 DOI: 10.1002/Bit.21194 |
0.324 |
|
2007 |
Westergaard SL, Oliveira APSd, Bro C, Olsson L, Nielsen J. A systems biology approach to study glucose repression in the yeast Saccharomyces cerevisiae Biotechnology and Bioengineering. 96: 134-145. PMID 16878332 DOI: 10.1002/Bit.21135 |
0.448 |
|
2007 |
Thykaer J, Nielsen J. Evidence, through C13-labelling analysis, of phosphoketolase activity in fungi Process Biochemistry. 42: 1050-1055. DOI: 10.1016/J.Procbio.2007.04.004 |
0.31 |
|
2007 |
Lantz AE, Wattanachaisaereekul S, Nielsen ML, Nielsen J. Towards a yeast cell factory platform for polyketide production Journal of Biotechnology. 131. DOI: 10.1016/J.Jbiotec.2007.07.355 |
0.313 |
|
2006 |
David HSM, Hofmann G, Oliveira APSd, Jarmer HØ, Nielsen J. Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans Genome Biology. 7: 1-16. PMID 17107606 DOI: 10.1186/Gb-2006-7-11-R108 |
0.424 |
|
2006 |
Regenberg B, Grotkjaer T, Winther O, Fausbøll A, Akesson M, Bro C, Hansen LK, Brunak S, Nielsen J. Growth-rate regulated genes have profound impact on interpretation of transcriptome profiling in Saccharomyces cerevisiae. Genome Biology. 7: R107. PMID 17105650 DOI: 10.1186/Gb-2006-7-11-R107 |
0.329 |
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2006 |
Çakir T, Patil KR, Önsan ZI, Ülgen KÖ, Kirdar B, Nielsen J. Integration of metabolome data with metabolic networks reveals reporter reactions Molecular Systems Biology. 2: 50-50. PMID 17016516 DOI: 10.1038/Msb4100085 |
0.37 |
|
2006 |
Usaite R, Patil KR, Grotkjær T, Nielsen J, Regenberg B. Global Transcriptional and Physiological Responses of Saccharomyces cerevisiae to Ammonium, l-Alanine, or l-Glutamine Limitation Applied and Environmental Microbiology. 72: 6194-6203. PMID 16957246 DOI: 10.1128/Aem.00548-06 |
0.34 |
|
2006 |
Diano A, Bekker-Jensen S, Dynesen JØ, Nielsen J. Polyol synthesis in Aspergillus niger: influence of oxygen availability, carbon and nitrogen sources on the metabolism. Biotechnology and Bioengineering. 94: 899-908. PMID 16718677 DOI: 10.1002/Bit.20915 |
0.355 |
|
2006 |
Mogensen J, Nielsen HB, Hofmann G, Nielsen J. Transcription analysis using high-density micro-arrays of Aspergillus nidulans wild-type and creA mutant during growth on glucose or ethanol. Fungal Genetics and Biology. 43: 593-603. PMID 16698295 DOI: 10.1016/J.Fgb.2006.03.003 |
0.337 |
|
2006 |
Raghevendran V, Patil KR, Olsson L, Nielsen J. Hap4 is not essential for activation of respiration at low specific growth rates in Saccharomyces cerevisiae. Journal of Biological Chemistry. 281: 12308-12314. PMID 16522629 DOI: 10.1074/Jbc.M512972200 |
0.418 |
|
2006 |
Mustacchi R, Hohmann S, Nielsen J. Yeast systems biology to unravel the network of life Yeast. 23: 227-238. PMID 16498699 DOI: 10.1002/Yea.1357 |
0.313 |
|
2006 |
Jewett MC, Hofmann G, Nielsen J. Fungal metabolite analysis in genomics and phenomics. Current Opinion in Biotechnology. 17: 191-7. PMID 16488600 DOI: 10.1016/J.Copbio.2006.02.001 |
0.409 |
|
2006 |
Eckert-Boulet N, Larsson K, Wu B, Poulsen P, Regenberg B, Nielsen J, Kielland-Brandt MC. Deletion of RTS1, encoding a regulatory subunit of protein phosphatase 2A, results in constitutive amino acid signaling via increased Stp1p processing. Eukaryotic Cell. 5: 174-9. PMID 16400180 DOI: 10.1128/Ec.5.1.174-179.2006 |
0.311 |
|
2006 |
Bro C, Regenberg B, Förster J, Nielsen J. In silico aided metabolic engineering of Saccharomyces cerevisiae for improved bioethanol production. Metabolic Engineering. 8: 102-11. PMID 16289778 DOI: 10.1016/J.Ymben.2005.09.007 |
0.722 |
|
2005 |
Raghevendran V, Nielsen J, Olsson L. Teaching microbial physiology using glucose repression phenomenon in baker's yeast as an example. Biochemistry and Molecular Biology Education. 33: 404-410. PMID 21638610 DOI: 10.1002/Bmb.2005.49403306404 |
0.328 |
|
2005 |
Patil KR, Rocha I, Förster J, Nielsen J. Evolutionary programming as a platform for in silico metabolic engineering. Bmc Bioinformatics. 6: 308. PMID 16375763 DOI: 10.1186/1471-2105-6-308 |
0.721 |
|
2005 |
Maury J, Asadollahi MA, Møller K, Clark A, Nielsen J. Microbial isoprenoid production: an example of green chemistry through metabolic engineering. Advances in Biochemical Engineering \/ Biotechnology. 100: 19-51. PMID 16270655 DOI: 10.1007/B136410 |
0.412 |
|
2005 |
Bro C, Knudsen S, Regenberg B, Olsson L, Nielsen J. Improvement of Galactose Uptake in Saccharomyces cerevisiae through Overexpression of Phosphoglucomutase: Example of Transcript Analysis as a Tool in Inverse Metabolic Engineering Applied and Environmental Microbiology. 71: 6465-6472. PMID 16269670 DOI: 10.1128/Aem.71.11.6465-6472.2005 |
0.394 |
|
2005 |
Nielsen J, Oliver S. The next wave in metabolome analysis Trends in Biotechnology. 23: 544-546. PMID 16154652 DOI: 10.1016/J.Tibtech.2005.08.005 |
0.345 |
|
2005 |
Grotkjær T, Christakopoulos P, Nielsen J, Olsson L. Comparative metabolic network analysis of two xylose fermenting recombinant Saccharomyces cerevisiae strains Metabolic Engineering. 7: 437-444. PMID 16140032 DOI: 10.1016/J.Ymben.2005.07.003 |
0.422 |
|
2005 |
David H, Krogh AM, Roca C, Akesson M, Nielsen J. CreA influences the metabolic fluxes of Aspergillus nidulans during growth on glucose and xylose. Microbiology (Reading, England). 151: 2209-21. PMID 16000711 DOI: 10.1099/Mic.0.27787-0 |
0.424 |
|
2005 |
Oliveira AP, Nielsen J, Förster J. Modeling Lactococcus lactis using a genome-scale flux model. Bmc Microbiology. 5: 39. PMID 15982422 DOI: 10.1186/1471-2180-5-39 |
0.721 |
|
2005 |
Borodina I, Nielsen J. From genomes to in silico cells via metabolic networks. Current Opinion in Biotechnology. 16: 350-355. PMID 15961036 DOI: 10.1016/J.Copbio.2005.04.008 |
0.415 |
|
2005 |
Borodina I, Krabben P, Nielsen J. Genome-scale analysis of Streptomyces coelicolor A3(2) metabolism Genome Research. 15: 820-829. PMID 15930493 DOI: 10.1101/Gr.3364705 |
0.41 |
|
2005 |
Borodina I, Schöller C, Eliasson A, Nielsen J. Metabolic network analysis of Streptomyces tenebrarius, a streptomyces species with an active entner-doudoroff pathway Applied and Environmental Microbiology. 71: 2294-2302. PMID 15870314 DOI: 10.1128/Aem.71.5.2294-2302.2005 |
0.409 |
|
2005 |
Villas-Bôas SG, Åkesson M, Nielsen J. Biosynthesis of glyoxylate from glycine in Saccharomyces cerevisiae. Fems Yeast Research. 5: 703-709. PMID 15851099 DOI: 10.1016/J.Femsyr.2005.03.001 |
0.408 |
|
2005 |
Patil KR, Nielsen J. Uncovering transcriptional regulation of metabolism by using metabolic network topology. Proceedings of the National Academy of Sciences of the United States of America. 102: 2685-2689. PMID 15710883 DOI: 10.1073/Pnas.0406811102 |
0.39 |
|
2005 |
Villas-Bôas SG, Moxley JF, Akesson M, Stephanopoulos G, Nielsen J. High-throughput metabolic state analysis: the missing link in integrated functional genomics of yeasts. The Biochemical Journal. 388: 669-77. PMID 15667247 DOI: 10.1042/Bj20041162 |
0.415 |
|
2005 |
Panagiotou G, Villas-Bôas SG, Christakopoulos P, Nielsen J, Olsson L. Intracellular metabolite profiling of Fusarium oxysporum converting glucose to ethanol. Journal of Biotechnology. 115: 425-434. PMID 15639104 DOI: 10.1016/J.Jbiotec.2004.09.011 |
0.622 |
|
2005 |
Smedsgaard J, Nielsen J. Metabolite profiling of fungi and yeast: from phenotype to metabolome by MS and informatics. Journal of Experimental Botany. 56: 273-286. PMID 15618299 DOI: 10.1093/Jxb/Eri068 |
0.433 |
|
2005 |
Eckert-Boulet N, Regenberg B, Nielsen J. Grr1p is required for transcriptional induction of amino acid permease genes and proper transcriptional regulation of genes in carbon metabolism of Saccharomyces cerevisiae Current Genetics. 47: 139-149. PMID 15611869 DOI: 10.1007/S00294-004-0553-1 |
0.387 |
|
2005 |
Seker T, Møller K, Nielsen J. Analysis of acyl CoA ester intermediates of the mevalonate pathway in Saccharomyces cerevisiae Applied Microbiology and Biotechnology. 67: 119-124. PMID 15448940 DOI: 10.1007/S00253-004-1697-0 |
0.366 |
|
2005 |
Villas-Bôas SG, Mas S, Åkesson MF, Smedsgaard J, Nielsen J. Mass spectrometry in metabolome analysis Mass Spectrometry Reviews. 24: 613-646. PMID 15389842 DOI: 10.1002/Mas.20032 |
0.32 |
|
2005 |
Jewett MC, Oliveira AP, Patil KR, Nielsen J. The role of high-throughput transcriptome analysis in metabolic engineering Biotechnology and Bioprocess Engineering. 10: 385-399. DOI: 10.1007/Bf02989821 |
0.412 |
|
2004 |
Gunnarsson N, Eliasson A, Nielsen J. Control of fluxes towards antibiotics and the role of primary metabolism in production of antibiotics Advances in Biochemical Engineering/Biotechnology. 88: 137-178. PMID 15719555 DOI: 10.1007/B99260 |
0.44 |
|
2004 |
Westergaard SL, Bro C, Olsson L, Nielsen J. Elucidation of the role of Grr1p in glucose sensing by Saccharomyces cerevisiae through genome-wide transcription analysis. Fems Yeast Research. 5: 193-204. PMID 15556081 DOI: 10.1016/J.Femsyr.2004.06.013 |
0.404 |
|
2004 |
Santos MMd, Raghevendran V, Kötter P, Olsson L, Nielsen J. Manipulation of malic enzyme in Saccharomyces cerevisiae for increasing NADPH production capacity aerobically in different cellular compartments Metabolic Engineering. 6: 352-363. PMID 15491864 DOI: 10.1016/J.Ymben.2004.06.002 |
0.376 |
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2004 |
Cannizzaro C, Christensen B, Nielsen J, von Stockar U. Metabolic network analysis on Phaffia rhodozyma yeast using 13C-labeled glucose and gas chromatography-mass spectrometry. Metabolic Engineering. 6: 340-51. PMID 15491863 DOI: 10.1016/J.Ymben.2004.06.001 |
0.425 |
|
2004 |
Akesson M, Förster J, Nielsen J. Integration of gene expression data into genome-scale metabolic models. Metabolic Engineering. 6: 285-93. PMID 15491858 DOI: 10.1016/J.Ymben.2003.12.002 |
0.731 |
|
2004 |
Gunnarsson N, Bruheim P, Nielsen J. Glucose metabolism in the antibiotic producing actinomycete Nonomuraea sp. ATCC 39727. Biotechnology and Bioengineering. 88: 652-663. PMID 15472928 DOI: 10.1002/Bit.20279 |
0.41 |
|
2004 |
Prathumpai W, Flitter SJ, McIntyre M, Nielsen J. Lipase production by recombinant strains of Aspergillus niger expressing a lipase-encoding gene from Thermomyces lanuginosus Applied Microbiology and Biotechnology. 65: 714-719. PMID 15316684 DOI: 10.1007/S00253-004-1699-Y |
0.363 |
|
2004 |
Raghevendran V, Gombert AK, Christensen B, Kötter P, Nielsen J. Phenotypic characterization of glucose repression mutants of Saccharomyces cerevisiae using experiments with 13C-labelled glucose. Yeast. 21: 769-779. PMID 15282800 DOI: 10.1002/Yea.1136 |
0.427 |
|
2004 |
Bro C, Nielsen J. Impact of 'ome' analyses on inverse metabolic engineering. Metabolic Engineering. 6: 204-211. PMID 15256210 DOI: 10.1016/J.Ymben.2003.11.005 |
0.397 |
|
2004 |
Eckert-Boulet N, Nielsen PS, Friis C, Santos MMd, Nielsen J, Kielland-Brandt MC, Regenberg B. Transcriptional profiling of extracellular amino acid sensing in Saccharomyces cerevisiae and the role of Stp1p and Stp2p. Yeast. 21: 635-648. PMID 15197729 DOI: 10.1002/Yea.1120 |
0.335 |
|
2004 |
Patil KR, Åkesson M, Nielsen J. Use of genome-scale microbial models for metabolic engineering Current Opinion in Biotechnology. 15: 64-69. PMID 15102469 DOI: 10.1016/J.Copbio.2003.11.003 |
0.386 |
|
2004 |
Gunnarsson N, Mortensen UH, Sosio M, Nielsen J. Identification of the Entner-Doudoroff pathway in an antibiotic-producing actinomycete species Molecular Microbiology. 52: 895-902. PMID 15101992 DOI: 10.1111/J.1365-2958.2004.04028.X |
0.44 |
|
2004 |
Bro C, Regenberg B, Nielsen J. Genome‐wide transcriptional response of a Saccharomyces cerevisiae strain with an altered redox metabolism Biotechnology and Bioengineering. 85: 269-276. PMID 14748081 DOI: 10.1002/Bit.10899 |
0.388 |
|
2004 |
Larsen GG, Appel KF, Wolff A, Nielsen J, Arnau J. Characterisation of the Mucor circinelloides regulated promoter gpd1P. Current Genetics. 45: 225-234. PMID 14735314 DOI: 10.1007/S00294-003-0484-2 |
0.341 |
|
2004 |
Lübbehüsen T, Polo VG, Rossi S, Nielsen J, Moreno S, McIntyre M, Arnau J. Protein kinase A is involved in the control of morphology and branching during aerobic growth of Mucor circinelloides. Microbiology. 150: 143-150. PMID 14702407 DOI: 10.1099/Mic.0.26708-0 |
0.33 |
|
2004 |
Møller K, Langkjær RB, Nielsen J, Piskur J, Olsson L. Pyruvate decarboxylases from the petite-negative yeast Saccharomyces kluyveri. Molecular Genetics and Genomics. 270: 558-568. PMID 14648197 DOI: 10.1007/S00438-003-0950-Z |
0.337 |
|
2004 |
Prathumpai W, Mcintyre M, Nielsen J. The effect of CreA in glucose and xylose catabolism in Aspergillus nidulans. Applied Microbiology and Biotechnology. 63: 748-753. PMID 12920487 DOI: 10.1007/S00253-003-1409-1 |
0.346 |
|
2004 |
Nielsen J. The First International Workshop on Systems Biology of Yeast, St. Louis, USA, 9 November, 2003 Fems Yeast Research. 4: 757-758. DOI: 10.1016/J.Femsyr.2004.02.001 |
0.344 |
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2003 |
Villas-Bôas SG, Delicado DG, Åkesson M, Nielsen J. Simultaneous analysis of amino and nonamino organic acids as methyl chloroformate derivatives using gas chromatography-mass spectrometry Analytical Biochemistry. 322: 134-138. PMID 14705791 DOI: 10.1016/J.Ab.2003.07.018 |
0.316 |
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2003 |
Nielsen J. It Is All about Metabolic Fluxes Journal of Bacteriology. 185: 7031-7035. PMID 14645261 DOI: 10.1128/Jb.185.24.7031-7035.2003 |
0.351 |
|
2003 |
David H, Åkesson M, Nielsen J. Reconstruction of the central carbon metabolism of Aspergillus niger Febs Journal. 270: 4243-4253. PMID 14622289 DOI: 10.1046/J.1432-1033.2003.03798.X |
0.459 |
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2003 |
Famili I, Forster J, Nielsen J, Palsson BO. Saccharomyces cerevisiae phenotypes can be predicted by using constraint-based analysis of a genome-scale reconstructed metabolic network. Proceedings of the National Academy of Sciences of the United States of America. 100: 13134-9. PMID 14578455 DOI: 10.1073/Pnas.2235812100 |
0.756 |
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2003 |
Santos MMd, Thygesen G, Kötter P, Olsson L, Nielsen J. Aerobic physiology of redox-engineered Saccharomyces cerevisiae strains modified in the ammonium assimilation for increased NADPH availability. Fems Yeast Research. 4: 59-68. PMID 14554197 DOI: 10.1016/S1567-1356(03)00155-7 |
0.37 |
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2003 |
Förster J, Famili I, Palsson BO, Nielsen J. Large-scale evaluation of in silico gene deletions in Saccharomyces cerevisiae. Omics : a Journal of Integrative Biology. 7: 193-202. PMID 14506848 DOI: 10.1089/153623103322246584 |
0.735 |
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2003 |
Roca C, Nielsen J, Olsson L. Metabolic Engineering of Ammonium Assimilation in Xylose-Fermenting Saccharomyces cerevisiae Improves Ethanol Production Applied and Environmental Microbiology. 69: 4732-4736. PMID 12902265 DOI: 10.1128/Aem.69.8.4732-4736.2003 |
0.335 |
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2003 |
Santos MMd, Gombert AK, Christensen B, Olsson L, Nielsen J. Identification of In Vivo Enzyme Activities in the Cometabolism of Glucose and Acetate by Saccharomyces cerevisiae by Using 13C-Labeled Substrates Eukaryotic Cell. 2: 599-608. PMID 12796305 DOI: 10.1128/Ec.2.3.599-608.2003 |
0.365 |
|
2003 |
Bro C, Regenberg B, Lagniel G, Labarre J, Montero-Lomelí M, Nielsen J. Transcriptional, proteomic, and metabolic responses to lithium in galactose-grown yeast cells. Journal of Biological Chemistry. 278: 32141-32149. PMID 12791685 DOI: 10.1074/Jbc.M304478200 |
0.391 |
|
2003 |
Robin JJC, Lettier G, Mcintyre M, Noorman H, Nielsen J. Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Growth yields and morphological characterization. Biotechnology and Bioengineering. 83: 361-368. PMID 12783492 DOI: 10.1002/Bit.10677 |
0.358 |
|
2003 |
Robin J, Bruheim P, Nielsen ML, Noorman H, Nielsen J. Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Kinetics of adipoyl-7-aminodeacetoxycephalosporanic acid and byproduct formations. Biotechnology and Bioengineering. 83: 353-360. PMID 12783491 DOI: 10.1002/Bit.10678 |
0.363 |
|
2003 |
Christiansen T, Michaelsen S, Wümpelmann M, Nielsen J. Production of Savinase and population viability of Bacillus clausii during high-cell-density fed-batch cultivations Biotechnology and Bioengineering. 83: 344-352. PMID 12783490 DOI: 10.1002/Bit.10675 |
0.319 |
|
2003 |
Thykaer J, Nielsen J. Metabolic engineering of β-lactam production Metabolic Engineering. 5: 56-69. PMID 12749845 DOI: 10.1016/S1096-7176(03)00003-X |
0.388 |
|
2003 |
Robin J, Bonneau S, Schipper D, Noorman H, Nielsen J. Influence of the adipate and dissolved oxygen concentrations on the beta-lactam production during continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus. Metabolic Engineering. 5: 42-8. PMID 12749843 DOI: 10.1016/S1096-7176(03)00006-5 |
0.302 |
|
2003 |
Hofmann G, McIntyre M, Nielsen J. Fungal genomics beyond Saccharomyces cerevisiae Current Opinion in Biotechnology. 14: 226-231. PMID 12732326 DOI: 10.1016/S0958-1669(03)00020-X |
0.304 |
|
2003 |
Förster J, Famili I, Fu P, Palsson BØ, Nielsen J. Genome-scale reconstruction of the Saccharomyces cerevisiae metabolic network. Genome Research. 13: 244-53. PMID 12566402 DOI: 10.1101/Gr.234503 |
0.741 |
|
2002 |
Møller K, Bro C, Piškur J, Nielsen J, Olsson L. Steady‐state and transient‐state analyses of aerobic fermentation in Saccharomyces kluyveri Fems Yeast Research. 2: 233-244. PMID 12702311 DOI: 10.1111/J.1567-1364.2002.Tb00088.X |
0.365 |
|
2002 |
Nielsen J, Olsson L. An expanded role for microbial physiology in metabolic engineering and functional genomics: moving towards systems biology Fems Yeast Research. 2: 175-181. PMID 12702306 DOI: 10.1111/J.1567-1364.2002.Tb00083.X |
0.393 |
|
2002 |
Müller C, Hjort CM, Hansen K, Nielsen J. Altering the expression of two chitin synthase genes differentially affects the growth and morphology of Aspergillus oryzae. Microbiology. 148: 4025-4033. PMID 12480906 DOI: 10.1099/00221287-148-12-4025 |
0.302 |
|
2002 |
Förster J, Gombert AK, Nielsen J. A functional genomics approach using metabolomics and in silico pathway analysis. Biotechnology and Bioengineering. 79: 703-12. PMID 12209793 DOI: 10.1002/Bit.10378 |
0.705 |
|
2002 |
Zaldivar J, Borges A, Johansson B, Smits HP, Villas-Boas SG, Nielsen J, Olsson L. Fermentation performance and intracellular metabolite patterns in laboratory and industrial xylose-fermenting Saccharomyces cerevisiae. Applied Microbiology and Biotechnology. 59: 436-442. PMID 12172606 DOI: 10.1007/S00253-002-1056-Y |
0.332 |
|
2002 |
Piper MD, Daran-Lapujade P, Bro C, Regenberg B, Knudsen S, Nielsen J, Pronk JT. Reproducibility of oligonucleotide microarray transcriptome analyses. An interlaboratory comparison using chemostat cultures of Saccharomyces cerevisiae. The Journal of Biological Chemistry. 277: 37001-8. PMID 12121991 DOI: 10.1074/Jbc.M204490200 |
0.372 |
|
2002 |
Christiansen T, Nielsen J. Production of extracellular protease and glucose uptake in Bacillus clausii in steady-state and transient continuous cultures. Journal of Biotechnology. 97: 265-273. PMID 12084482 DOI: 10.1016/S0168-1656(02)00109-8 |
0.322 |
|
2002 |
Christensen B, Gombert AK, Nielsen J. Analysis of flux estimates based on 13C-labelling experiments Febs Journal. 269: 2795-2800. PMID 12047390 DOI: 10.1046/J.1432-1033.2002.02959.X |
0.354 |
|
2002 |
Christiansen T, Christensen B, Nielsen J. Metabolic Network Analysis of Bacillus clausii on Minimal and Semirich Medium Using 13C-Labeled Glucose Metabolic Engineering. 4: 159-169. PMID 12009795 DOI: 10.1006/Mben.2001.0219 |
0.394 |
|
2002 |
Thykaer J, Christensen B, Nielsen J. Metabolic network analysis of an adipoyl-7-ADCA-producing strain of Penicillium chrysogenum: elucidation of adipate degradation. Metabolic Engineering. 4: 151-158. PMID 12009794 DOI: 10.1006/Mben.2001.0218 |
0.406 |
|
2002 |
McIntyre M, Breum J, Arnau J, Nielsen J. Growth physiology and dimorphism of Mucor circinelloides (syn. racemosus) during submerged batch cultivation. Applied Microbiology and Biotechnology. 58: 495-502. PMID 11954797 DOI: 10.1007/S00253-001-0916-1 |
0.303 |
|
2002 |
Müller C, McIntyre M, Hansen K, Nielsen J. Metabolic engineering of the morphology of Aspergillus oryzae by altering chitin synthesis. Applied and Environmental Microbiology. 68: 1827-1836. PMID 11916702 DOI: 10.1128/Aem.68.4.1827-1836.2002 |
0.321 |
|
2002 |
Jonsbu E, McIntyre M, Nielsen J. The influence of carbon sources and morphology on nystatin production by Streptomyces noursei. Journal of Biotechnology. 95: 133-144. PMID 11911923 DOI: 10.1016/S0168-1656(02)00003-2 |
0.336 |
|
2002 |
Vara AG, Hochkoepple A, Nielsen J, Villadsen J. Production of teicoplanin by Actinoplanes teichomyceticus in continuous fermentation Biotechnology and Bioengineering. 77: 589-598. PMID 11788956 DOI: 10.1002/Bit.10137 |
0.333 |
|
2002 |
Møller K, Christensen B, Förster J, Piskur J, Nielsen J, Olsson L. Aerobic glucose metabolism of Saccharomyces kluyveri: growth, metabolite production, and quantification of metabolic fluxes. Biotechnology and Bioengineering. 77: 186-93. PMID 11753925 DOI: 10.1002/Bit.10122 |
0.7 |
|
2002 |
Agger T, Petersen JB, O'Connor SM, Murphy RL, Kelly JM, Nielsen J. Physiological characterisation of recombinant Aspergillus nidulans strains with different creA genotypes expressing A. oryzae alpha-amylase. Journal of Biotechnology. 92: 279-85. PMID 11689252 DOI: 10.1016/S0168-1656(01)00366-2 |
0.311 |
|
2002 |
Zangirolami T, Carlsen M, Nielsen J, Jørgensen SB. GROWTH AND ENZYME PRODUCTION DURING CONTINUOUS CULTURES OF A HIGH AMYLASE-PRODUCING VARIANT OF Aspergillus Oryzae Brazilian Journal of Chemical Engineering. 19: 55-68. DOI: 10.1590/S0104-66322002000100005 |
0.36 |
|
2002 |
Christiansen T, Nielsen J. Growth energetics of an alkaline serine protease-producing strain of Bacillus clausii during continuous cultivation Bioprocess and Biosystems Engineering. 24: 329-339. DOI: 10.1007/S00449-001-0276-3 |
0.335 |
|
2001 |
Ostergaard S, Walløe KO, Gomes CSG, Olsson L, Nielsen J. The impact of GAL6, GAL80, and MIG1 on glucose control of the GAL system in Saccharomyces cerevisiae Fems Yeast Research. 1: 47-55. PMID 12702462 DOI: 10.1111/J.1567-1364.2001.Tb00012.X |
0.335 |
|
2001 |
McIntyre M, Müller C, Dynesen J, Nielsen J. Metabolic engineering of the morphology of Aspergillus. Advances in Biochemical Engineering \/ Biotechnology. 73: 103-128. PMID 11816809 DOI: 10.1007/3-540-45300-8_6 |
0.337 |
|
2001 |
Robin JJC, Jakobsen M, Beyer M, Noorman H, Nielsen J. Physiological characterisation of Penicillium chrysogenum strains expressing the expandase gene from Streptomyces clavuligerus during batch cultivations. Growth and adipoyl-7-aminodeacetoxycephalosporanic acid production. Applied Microbiology and Biotechnology. 57: 357-362. PMID 11759685 DOI: 10.1007/S002530100787 |
0.358 |
|
2001 |
Carlsen M, Nielsen J. Influence of carbon source on alpha-amylase production by Aspergillus oryzae. Applied Microbiology and Biotechnology. 57: 346-349. PMID 11759683 DOI: 10.1007/S002530100772 |
0.325 |
|
2001 |
Møller K, Tidemand LD, Winther JR, Olsson L, Piskur J, Nielsen J. Production of a heterologous proteinase A by Saccharomyces kluyveri. Applied Microbiology and Biotechnology. 57: 216-219. PMID 11693924 DOI: 10.1007/S002530100680 |
0.327 |
|
2001 |
Jonsbu E, Christensen B, Nielsen J. Changes of in vivo fluxes through central metabolic pathways during the production of nystatin by Streptomyces noursei in batch culture Applied Microbiology and Biotechnology. 56: 93-100. PMID 11499953 DOI: 10.1007/S002530100613 |
0.406 |
|
2001 |
Zaldivar J, Nielsen J, Olsson L. Fuel ethanol production from lignocellulose: a challenge for metabolic engineering and process integration. Applied Microbiology and Biotechnology. 56: 17-34. PMID 11499926 DOI: 10.1007/S002530100624 |
0.328 |
|
2001 |
Christensen B, Christiansen T, Gombert AK, Thykaer J, Nielsen J. Simple and robust method for estimation of the split between the oxidative pentose phosphate pathway and the Embden-Meyerhof-Parnas pathway in microorganisms. Biotechnology and Bioengineering. 74: 517-523. PMID 11494219 DOI: 10.1002/Bit.1143 |
0.351 |
|
2001 |
Ostergaard S, Olsson L, Nielsen J. In vivo dynamics of galactose metabolism in Saccharomyces cerevisiae: metabolic fluxes and metabolite levels. Biotechnology and Bioengineering. 73: 412-425. PMID 11320512 DOI: 10.1002/Bit.1075 |
0.38 |
|
2001 |
Agger T, Spohr AB, Nielsen J. alpha-Amylase production in high cell density submerged cultivation of Aspergillus oryzae and A. nidulans. Applied Microbiology and Biotechnology. 55: 81-84. PMID 11234963 DOI: 10.1007/S002530000456 |
0.316 |
|
2001 |
Theilgaard HA, Berg MAvd, Mulder CA, Bovenberg RAL, Nielsen J. Quantitative analysis of Penicillium chrysogenum Wis54-1255 transformants overexpressing the penicillin biosynthetic genes. Biotechnology and Bioengineering. 72: 379-388. PMID 11180058 DOI: 10.1002/1097-0290(20000220)72:4<379::Aid-Bit1000>3.0.Co;2-5 |
0.335 |
|
2001 |
McIntyre M, Dynesen J, Nielsen J. Morphological characterization of Aspergillus nidulans: growth, septation and fragmentation. Microbiology. 147: 239-246. PMID 11160817 DOI: 10.1099/00221287-147-1-239 |
0.304 |
|
2001 |
Gombert AK, Santos MMd, Christensen B, Nielsen J. Network Identification and Flux Quantification in the Central Metabolism of Saccharomyces cerevisiae under Different Conditions of Glucose Repression Journal of Bacteriology. 183: 1441-1451. PMID 11157958 DOI: 10.1128/Jb.183.4.1441-1451.2001 |
0.419 |
|
2001 |
Nissen TL, Anderlund M, Nielsen J, Villadsen J, Kielland-Brandt MC. Expression of a cytoplasmic transhydrogenase in Saccharomyces cerevisiae results in formation of 2-oxoglutarate due to depletion of the NADPH pool. Yeast. 18: 19-32. PMID 11124698 DOI: 10.1002/1097-0061(200101)18:1<19::Aid-Yea650>3.0.Co;2-5 |
0.388 |
|
2000 |
Jonsbu E, Ellingsen TE, Nielsen J. Effects of nitrogen sources on cell growth and production of nystatin by Streptomyces noursei. The Journal of Antibiotics. 53: 1354-1362. PMID 11217800 DOI: 10.7164/Antibiotics.53.1354 |
0.316 |
|
2000 |
Ostergaard S, Olsson L, Johnston M, Nielsen J. Increasing galactose consumption by Saccharomyces cerevisiae through metabolic engineering of the GAL gene regulatory network. Nature Biotechnology. 18: 1283-1286. PMID 11101808 DOI: 10.1038/82400 |
0.463 |
|
2000 |
Bautista LF, Aleksenko A, Hentzer M, Santerre-Henriksen A, Nielsen J. Antisense silencing of the creA gene in Aspergillus nidulans. Applied and Environmental Microbiology. 66: 4579-4581. PMID 11010922 DOI: 10.1128/Aem.66.10.4579-4581.2000 |
0.332 |
|
2000 |
Christensen B, Thykær J, Nielsen J. Metabolic characterization of high- and low-yielding strains of Penicillium chrysogenum Applied Microbiology and Biotechnology. 54: 212-217. PMID 10968635 DOI: 10.1007/S002530000371 |
0.378 |
|
2000 |
Nissen TL, Kielland-Brandt MC, Nielsen J, Villadsen J. Optimization of Ethanol Production in Saccharomyces Cerevisiae by Metabolic Engineering of the Ammonium Assimilation Metabolic Engineering. 2: 69-77. PMID 10935936 DOI: 10.1006/Mben.1999.0140 |
0.359 |
|
2000 |
Pedersen H, Christensen B, Hjort C, Nielsen J. Construction and Characterization of an Oxalic Acid Nonproducing Strain of Aspergillus niger Metabolic Engineering. 2: 34-41. PMID 10935933 DOI: 10.1006/Mben.1999.0136 |
0.38 |
|
2000 |
Olsson L, Nielsen J. The role of metabolic engineering in the improvement of Saccharomyces cerevisiae: utilization of industrial media. Enzyme and Microbial Technology. 26: 785-792. PMID 10862886 DOI: 10.1016/S0141-0229(00)00172-1 |
0.396 |
|
2000 |
Christensen B, Nielsen J. Metabolic network analysis of penicillium chrysogenum using 13c‐labeled glucose Biotechnology and Bioengineering. 68: 652-659. PMID 10799990 DOI: 10.1002/(Sici)1097-0290(20000620)68:6<652::Aid-Bit8>3.0.Co;2-J |
0.357 |
|
2000 |
Pedersen H, Beyer M, Nielsen J. Glucoamylase production in batch, chemostat and fed-batch cultivations by an industrial strain of Aspergillus niger. Applied Microbiology and Biotechnology. 53: 272-277. PMID 10772465 DOI: 10.1007/S002530050020 |
0.348 |
|
2000 |
Gombert AK, Nielsen J. Mathematical modelling of metabolism. Current Opinion in Biotechnology. 11: 180-186. PMID 10753761 DOI: 10.1016/S0958-1669(00)00079-3 |
0.425 |
|
2000 |
Østergaard S, Roca CFA, Ronnow B, Nielsen J, Olsson L. Physiological studies in aerobic batch cultivations of Saccharomyces cerevisiae strains harboring the MEL1 gene Biotechnology and Bioengineering. 68: 252-259. PMID 10745193 DOI: 10.1002/(Sici)1097-0290(20000505)68:3<252::Aid-Bit3>3.0.Co;2-K |
0.324 |
|
2000 |
Nissen TL, Hamann CW, Kielland-Brandt MC, Nielsen J, Villadsen J. Anaerobic and aerobic batch cultivations of Saccharomyces cerevisiae mutants impaired in glycerol synthesis Yeast. 16: 463-474. PMID 10705374 DOI: 10.1002/(Sici)1097-0061(20000330)16:5<463::Aid-Yea535>3.0.Co;2-3 |
0.364 |
|
2000 |
Ostergaard S, Olsson L, Nielsen J. Metabolic Engineering of Saccharomyces cerevisiae Microbiology and Molecular Biology Reviews. 64: 34-50. PMID 10704473 DOI: 10.1128/Mmbr.64.1.34-50.2000 |
0.406 |
|
2000 |
Heydorn A, Petersen BO, Duus JO, Bergmann S, Suhr-Jessen T, Nielsen J. Biosynthetic studies of the glycopeptide teicoplanin by (1)H and (13)C NMR. The Journal of Biological Chemistry. 275: 6201-6. PMID 10692413 DOI: 10.1074/Jbc.275.9.6201 |
0.305 |
|
2000 |
Zangirolami TC, Carlsen M, Nielsen J, Jørgensen SB. Selection and characterization of a high α-amylase-producing variant in glucose-limited continuous cultures of Aspergillus oryzae Fungal Biology. 104: 1241-1249. DOI: 10.1017/S0953756200002665 |
0.307 |
|
1999 |
Rønnow B, Olsson L, Nielsen J, Mikkelsen JD. Derepression of galactose metabolism in melibiase producing bakers' and distillers' yeast. Journal of Biotechnology. 72: 213-228. PMID 12680392 DOI: 10.1016/S0168-1656(99)00108-X |
0.349 |
|
1999 |
Agger T, Nielsen J. Genetically structured modeling of protein production in filamentous fungi Biotechnology and Bioengineering. 66: 164-170. PMID 10577470 DOI: 10.1002/(Sici)1097-0290(1999)66:3<164::Aid-Bit4>3.0.Co;2-O |
0.339 |
|
1999 |
Schmidt K, Nielsen J, Villadsen J. Quantitative analysis of metabolic fluxes in Escherichia coli, using two-dimensional NMR spectroscopy and complete isotopomer models. Journal of Biotechnology. 71: 175-189. PMID 10483105 DOI: 10.1016/S0168-1656(99)00021-8 |
0.397 |
|
1999 |
Aleksenko A, Liu W, Gojkovic Z, Nielsen J, Piskur J. Structural and transcriptional analysis of the pyrABCN, pyrD and pyrF genes in Aspergillus nidulans and the evolutionary origin of fungal dihydroorotases. Molecular Microbiology. 33: 599-611. PMID 10417650 DOI: 10.1046/J.1365-2958.1999.01507.X |
0.321 |
|
1999 |
Anderlund M, Nissen TL, Nielsen J, Villadsen J, Rydström J, Hahn-Hägerdal B, Kielland-Brandt MC. Expression of the Escherichia coli pntA and pntB Genes, Encoding Nicotinamide Nucleotide Transhydrogenase, in Saccharomyces cerevisiae and Its Effect on Product Formation during Anaerobic Glucose Fermentation Applied and Environmental Microbiology. 65: 2333-2340. PMID 10347010 DOI: 10.1128/Aem.65.6.2333-2340.1999 |
0.334 |
|
1999 |
Santerre Henriksen AL, Even S, Müller C, Punt PJ, van den Hondel CA, Nielsen J. Study of the glucoamylase promoter in Aspergillus niger using green fluorescent protein. Microbiology (Reading, England). 145: 729-34. PMID 10217507 DOI: 10.1099/13500872-145-3-729 |
0.321 |
|
1999 |
Klein CL, Rasmussen J, Rønnow B, Olsson L, Nielsen J. Investigation of the impact of MIG1 and MIG2 on the physiology of Saccharomyces cerevisiae. Journal of Biotechnology. 68: 197-212. PMID 10194857 DOI: 10.1016/S0168-1656(98)00205-3 |
0.382 |
|
1998 |
Henriksen CM, Nielsen J, Villadsen J. High exogenous concentrations of phenoxyacetic acid are crucial for a high penicillin V productivity in Penicillium chrysogenum Microbiology. 144: 2001-2006. PMID 33757233 DOI: 10.1099/00221287-144-7-2001 |
0.329 |
|
1998 |
Schmidt K, Marx A, Graaf AAd, Wiechert W, Sahm H, Nielsen J, Villadsen J. 13C tracer experiments and metabolite balancing for metabolic flux analysis: comparing two approaches Biotechnology and Bioengineering. 58: 254-257. PMID 10191397 DOI: 10.1002/(Sici)1097-0290(19980420)58:2/3<254::Aid-Bit19>3.0.Co;2-C |
0.385 |
|
1998 |
Nielsen J. Metabolic engineering: techniques for analysis of targets for genetic manipulations. Biotechnology and Bioengineering. 58: 125-132. PMID 10191381 DOI: 10.1002/(Sici)1097-0290(19980420)58:2/3<125::Aid-Bit3>3.0.Co;2-N |
0.412 |
|
1998 |
Dynesen J, Smits HP, Olsson L, Nielsen J. Carbon catabolite repression of invertase during batch cultivations of Saccharomyces cerevisiae : the role of glucose, fructose, and mannose Applied Microbiology and Biotechnology. 50: 579-582. PMID 9866176 DOI: 10.1007/S002530051338 |
0.321 |
|
1998 |
Spohr A, Carlsen M, Nielsen J, Villadsen J. α-Amylase production in recombinant Aspergillus oryzae during fed-batch and continuous cultivations Journal of Fermentation and Bioengineering. 86: 49-56. DOI: 10.1016/S0922-338X(98)80033-0 |
0.316 |
|
1997 |
Zangirolami TC, Johansen CL, Nielsen J, Jørgensen SB. Simulation of penicillin production in fed-batch cultivations using a morphologically structured model. Biotechnology and Bioengineering. 56: 593-604. PMID 18642330 DOI: 10.1002/(Sici)1097-0290(19971220)56:6<593::Aid-Bit1>3.0.Co;2-I |
0.32 |
|
1997 |
Olsson L, Larsen ME, Rønnow B, Mikkelsen JD, Nielsen J. Silencing MIG1 in Saccharomyces cerevisiae: Effects of Antisense MIG1 Expression and MIG1 Gene Disruption Applied and Environmental Microbiology. 63: 2366-2371. PMID 9172357 DOI: 10.1128/Aem.63.6.2366-2371.1997 |
0.31 |
|
1997 |
Nielsen J. Metabolic control analysis of biochemical pathways based on a thermokinetic description of reaction rates Biochemical Journal. 321: 133-138. PMID 9003411 DOI: 10.1042/Bj3210133 |
0.337 |
|
1997 |
Pissarra PDN, Nielsen J. Thermodynamics of Metabolic Pathways for Penicillin Production: Analysis of Thermodynamic Feasibility and Free Energy Changes During Fed‐Batch Cultivation Biotechnology Progress. 13: 156-165. DOI: 10.1021/Bp970010C |
0.352 |
|
1996 |
Pissara PdN, Nielsen J, Bazin MJ. Pathway kinetics and metabolic control analysis of a high-yielding strain of Penicillium chrysogenum during fed batch cultivations. Biotechnology and Bioengineering. 51: 168-176. PMID 18624326 DOI: 10.1002/(Sici)1097-0290(19960720)51:2<168::Aid-Bit6>3.0.Co;2-H |
0.372 |
|
1996 |
Klein CJ, Olsson L, Rønnow B, Mikkelsen JD, Nielsen J. Alleviation of glucose repression of maltose metabolism by MIG1 disruption in Saccharomyces cerevisiae. Applied and Environmental Microbiology. 62: 4441-4449. PMID 8953715 DOI: 10.1128/Aem.62.12.4441-4449.1996 |
0.365 |
|
1996 |
Carlsen M, Nielsen J, Villadsen J. Growth and α-amylase production by Aspergillus oryzae during continuous cultivations Journal of Biotechnology. 45: 81-93. DOI: 10.1016/0168-1656(95)00147-6 |
0.343 |
|
1995 |
Jørgensen H, Nielsen J, Villadsen J, Møllgaard H. Metabolic flux distributions in Penicillium chrysogenum during fed‐batch cultivations Biotechnology and Bioengineering. 46: 117-131. PMID 18623271 DOI: 10.1002/Bit.260460205 |
0.363 |
|
1995 |
Jørgensen H, Nielsen J, Villadsen J, Møllgaard H. Analysis of penicillin V biosynthesis during fed-batch cultivations with a high-yielding strain of Penicillium chrysogenum. Applied Microbiology and Biotechnology. 43: 123-130. PMID 7766125 DOI: 10.1007/Bf00170633 |
0.324 |
|
1995 |
Nielsen J, Jørgensen HS. Metabolic Control Analysis of the Penicillin Biosynthetic Pathway in a High‐Yielding Strain of Penicillium chrysogenum Biotechnology Progress. 11: 299-305. PMID 7619400 DOI: 10.1021/Bp00033A010 |
0.365 |
|
1995 |
Mørkeberg R, Carlsen M, Nielsen J. Induction and repression of α-amylase production in batch and continuous cultures of Aspergillus oryzae Microbiology. 141: 2449-2454. PMID 7582005 DOI: 10.1099/13500872-141-10-2449 |
0.307 |
|
1995 |
Christensen LH, Henriksen CM, Nielsen J, Villadsen J, Egel-Mitani M. Continuous cultivation of Penicillium chrysogenum. Growth on glucose and penicillin production. Journal of Biotechnology. 42: 95-107. PMID 7576537 DOI: 10.1016/0168-1656(95)00056-V |
0.361 |
|
1995 |
Nielsen J, Jørgensen HS. A Kinetic Model for the Penicillin Biosynthetic Pathway in Penicillium Chrysogenum Ifac Proceedings Volumes. 28: 136-141. DOI: 10.1016/S1474-6670(17)45615-1 |
0.318 |
|
1995 |
Min RW, Nielsen J, Villadsen J. Simultaneous monitoring of glucose, lactic acid and penicillin by sequential injection analysis Analytica Chimica Acta. 312: 149-156. DOI: 10.1016/0003-2670(95)00239-V |
0.305 |
|
1994 |
Benthin S, Nielsen J, Villadsen J. Galactose Expulsion during Lactose Metabolism in Lactococcus lactis subsp. cremoris FD1 Due to Dephosphorylation of Intracellular Galactose 6-Phosphate Applied and Environmental Microbiology. 60: 1254-1259. PMID 16349233 DOI: 10.1128/Aem.60.4.1254-1259.1994 |
0.345 |
|
1994 |
Nielsen J, Johansen CL, Villadsen J. Culture fluorescence measurements during batch and fed-batch cultivations with Penicillium chrysogenum Journal of Biotechnology. 38: 51-62. DOI: 10.1016/0168-1656(94)90147-3 |
0.31 |
|
1993 |
Benthin S, Nielsen J, Villadsen J. Two uptake systems for fructose in Lactococcus lactis subsp. cremoris FD1 produce glycolytic and gluconeogenic fructose phosphates and induce oscillations in growth and lactic acid formation Applied and Environmental Microbiology. 59: 3206-3211. PMID 16349061 DOI: 10.1128/Aem.59.10.3206-3211.1993 |
0.324 |
|
1992 |
Nielsen J. Modelling the growth of filamentous fungi Advances in Biochemical Engineering/Biotechnology. 46: 187-223. PMID 1636480 DOI: 10.1007/Bfb0000711 |
0.308 |
|
1992 |
Nielsen J, Villadsen J. Modelling of microbial kinetics Chemical Engineering Science. 47: 4225-4270. DOI: 10.1016/0009-2509(92)85104-J |
0.31 |
|
1992 |
Benthin S, Nielsen J, Villadsen J. Flow-injection analysis of micromolar concentrations of glucose and lactate in fermentation media Analytica Chimica Acta. 261: 145-153. DOI: 10.1016/0003-2670(92)80185-A |
0.307 |
|
1992 |
Strudsholm K, Nielsen J, Emborg C. Product formation during batch fermentation with recombinant Escherichia coli containing a runaway plasmid Bioprocess Engineering. 8: 173-181. DOI: 10.1007/Bf01254234 |
0.316 |
|
1991 |
Nikolajsen K, Nielsen J, Villadsen J. Structured modeling of a microbial system: III. Growth on mixed substrates Biotechnology and Bioengineering. 38: 24-29. PMID 18600694 DOI: 10.1002/Bit.260380104 |
0.328 |
|
1991 |
Nielsen J, Nikolajsen K, Villadsen J. Structured modeling of a microbial system: II. Experimental verification of a structured lactic acid fermentation model Biotechnology and Bioengineering. 38: 11-23. PMID 18600693 DOI: 10.1002/Bit.260380103 |
0.331 |
|
1991 |
Nielsen J, Nikolajsen K, Villadsen J. Structured modeling of a microbial system: I. A theoretical study of lactic acid fermentation. Biotechnology and Bioengineering. 38: 1-10. PMID 18600692 DOI: 10.1002/Bit.260380102 |
0.308 |
|
1991 |
Benthin S, Nielsen J, Villadsen J. Characterization and application of precise and robust flow-injection analysers for on-line measurement during fermentations Analytica Chimica Acta. 247: 45-50. DOI: 10.1016/S0003-2670(00)83050-0 |
0.305 |
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1989 |
Nielsen J, Nikolajsen K, Villadsen J. FIA for on-line monitoring of important lactic acid fermentation variables. Biotechnology and Bioengineering. 33: 1127-1134. PMID 18588030 DOI: 10.1002/Bit.260330908 |
0.302 |
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