| Year |
Citation |
Score |
| 2023 |
Rodríguez-Periñán G, de la Encarnación A, Moreno F, López de Munain A, Martínez A, Martín-Requero Á, Alquézar C, Bartolomé F. Progranulin Deficiency Induces Mitochondrial Dysfunction in Frontotemporal Lobar Degeneration with TDP-43 Inclusions. Antioxidants (Basel, Switzerland). 12. PMID 36978829 DOI: 10.3390/antiox12030581 |
0.663 |
|
| 2022 |
Hwang JL, Perloff OS, Gaus SE, Benitez C, Alquezar C, Cosme CQ, Nana AL, Vatsavayai SC, Ramos EM, Geschwind DH, Miller BL, Kao AW, Seeley WW. Tuberous sclerosis complex is associated with a novel human tauopathy. Acta Neuropathologica. PMID 36469115 DOI: 10.1007/s00401-022-02521-5 |
0.691 |
|
| 2022 |
Chin MY, Ang KH, Davies J, Alquezar C, Garda VG, Rooney B, Leng K, Kampmann M, Arkin MR, Kao AW. Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model. Acs Chemical Neuroscience. 13: 1505-1516. PMID 35522480 DOI: 10.1021/acschemneuro.1c00804 |
0.637 |
|
| 2021 |
Alquezar C, Schoch KM, Geier EG, Ramos EM, Scrivo A, Li KH, Argouarch AR, Mlynarski EE, Dombroski B, DeTure M, Dickson DW, Yokoyama JS, Cuervo AM, Burlingame AL, Schellenberg GD, et al. TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy. Science Advances. 7: eabg3897. PMID 34739309 DOI: 10.1126/sciadv.abg3897 |
0.679 |
|
| 2021 |
Chin MY, Patwardhan AR, Ang KH, Wang AL, Alquezar C, Welch M, Nguyen PT, Grabe M, Molofsky AV, Arkin MR, Kao AW. Genetically Encoded, pH-Sensitive mTFP1 Biosensor for Probing Lysosomal pH. Acs Sensors. PMID 34102054 DOI: 10.1021/acssensors.0c02318 |
0.601 |
|
| 2020 |
Alquezar C, Arya S, Kao AW. Tau Post-translational Modifications: Dynamic Transformers of Tau Function, Degradation, and Aggregation. Frontiers in Neurology. 11: 595532. PMID 33488497 DOI: 10.3389/fneur.2020.595532 |
0.756 |
|
| 2020 |
Alquezar C, Felix JB, McCandlish E, Buckley BT, Caparros-Lefebvre D, Karch CM, Golbe LI, Kao AW. Heavy metals contaminating the environment of a progressive supranuclear palsy cluster induce tau accumulation and cell death in cultured neurons. Scientific Reports. 10: 569. PMID 31953414 DOI: 10.1038/S41598-019-56930-W |
0.689 |
|
| 2020 |
Nuñez-Borque E, González-Naranjo P, Bartolomé F, Alquézar C, Reinares-Sebastián A, Pérez C, Ceballos ML, Páez JA, Campillo NE, Martín-Requero Á. Targeting Cannabinoid Receptor Activation and BACE-1 Activity Counteracts TgAPP Mice Memory Impairment and Alzheimer's Disease Lymphoblast Alterations. Molecular Neurobiology. PMID 31898159 DOI: 10.1007/s12035-019-01813-4 |
0.677 |
|
| 2019 |
Cosín-Tomàs M, Senserrich J, Arumí-Planas M, Alquézar C, Pallàs M, Martín-Requero Á, Suñol C, Kaliman P, Sanfeliu C. Role of Resveratrol and Selenium on Oxidative Stress and Expression of Antioxidant and Anti-Aging Genes in Immortalized Lymphocytes from Alzheimer's Disease Patients. Nutrients. 11. PMID 31370365 DOI: 10.3390/nu11081764 |
0.668 |
|
| 2018 |
Del Cerro P, Alquézar C, Bartolomé F, González-Naranjo P, Pérez C, Carro E, Páez JA, Campillo NE, Martín-Requero Á. Activation of the Cannabinoid Type 2 Receptor by a Novel Indazole Derivative Normalizes the Survival Pattern of Lymphoblasts from Patients with Late-Onset Alzheimer's Disease. Cns Drugs. PMID 29736745 DOI: 10.1007/s40263-018-0515-7 |
0.678 |
|
| 2017 |
Olney NT, Alquezar C, Ramos EM, Nana AL, Fong JC, Karydas AM, Taylor JB, Stephens ML, Argouarch AR, Van Berlo VA, Dokuru DR, Sherr EH, Jicha GA, Dillon WP, Desikan RS, et al. Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia. Acta Neuropathologica. PMID 28828560 DOI: 10.1007/S00401-017-1764-0 |
0.644 |
|
| 2017 |
Wojsiat J, Laskowska-Kaszub K, Alquézar C, Białopiotrowicz E, Esteras N, Zdioruk M, Martin-Requero A, Wojda U. Familial Alzheimer's Disease Lymphocytes Respond Differently Than Sporadic Cells to Oxidative Stress: Upregulated p53-p21 Signaling Linked with Presenilin 1 Mutants. Molecular Neurobiology. 54: 5683-5698. PMID 27644130 DOI: 10.1007/s12035-016-0105-y |
0.687 |
|
| 2016 |
Alquezar C, Salado IG, de la Encarnación A, Pérez DI, Moreno F, Gil C, de Munain AL, Martínez A, Martín-Requero Á. Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia. Molecular Neurodegeneration. 11: 36. PMID 27138926 DOI: 10.1186/S13024-016-0102-7 |
0.699 |
|
| 2016 |
de la Encarnación A, Alquézar C, Martín-Requero Á. Increased Wnt Signaling and Reduced Viability in a Neuronal Model of Progranulin-Deficient Frontotemporal Lobar Degeneration. Molecular Neurobiology. 53: 7107-7118. PMID 26676574 DOI: 10.1007/s12035-015-9596-1 |
0.688 |
|
| 2016 |
Alquézar C, de la Encarnación A, Moreno F, López de Munain A, Martín-Requero Á. Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers. Journal of Psychiatry & Neuroscience : Jpn. 41: 225-39. PMID 26624524 DOI: 10.1503/jpn.150131 |
0.7 |
|
| 2016 |
Esteras N, Alquézar C, de la Encarnación A, Martín-Requero Á. Lymphocytes in Alzheimer's disease pathology: Altered signaling pathways. Current Alzheimer Research. 13: 439-49. PMID 26567747 DOI: 10.2174/1567205013666151116124912 |
0.7 |
|
| 2015 |
Alquézar C, Barrio E, Esteras N, de la Encarnación A, Bartolomé F, Molina JA, Martín-Requero Á. Targeting cyclin D3/CDK6 activity for treatment of Parkinson's disease. Journal of Neurochemistry. 133: 886-97. PMID 25689470 DOI: 10.1111/jnc.13070 |
0.674 |
|
| 2015 |
Alquezar C, Esteras N, de la Encarnación A, Moreno F, López de Munain A, Martín-Requero Á. Increasing progranulin levels and blockade of the ERK1/2 pathway: upstream and downstream strategies for the treatment of progranulin deficient frontotemporal dementia. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 25: 386-403. PMID 25624003 DOI: 10.1016/j.euroneuro.2014.12.007 |
0.732 |
|
| 2015 |
de la Encarnación A, Alquézar C, Esteras N, Martín-Requero Á. Progranulin Deficiency Reduces CDK4/6/pRb Activation and Survival of Human Neuroblastoma SH-SY5Y Cells. Molecular Neurobiology. 52: 1714-1725. PMID 25377796 DOI: 10.1007/s12035-014-8965-5 |
0.703 |
|
| 2015 |
Esteras N, Alquézar C, Bartolomé F, de la Encarnación A, Bermejo-Pareja F, Molina JA, Martín-Requero Á. G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients. Molecular Neurobiology. 52: 386-98. PMID 25182869 DOI: 10.1007/s12035-014-8870-y |
0.678 |
|
| 2014 |
Alquézar C, Esteras N, de la Encarnación A, Alzualde A, Moreno F, López de Munain A, Martín-Requero A. PGRN haploinsufficiency increased Wnt5a signaling in peripheral cells from frontotemporal lobar degeneration-progranulin mutation carriers. Neurobiology of Aging. 35: 886-98. PMID 24139281 DOI: 10.1016/j.neurobiolaging.2013.09.021 |
0.714 |
|
| 2013 |
Esteras N, Alquézar C, de la Encarnación A, Villarejo A, Bermejo-Pareja F, Martín-Requero A. Calmodulin levels in blood cells as a potential biomarker of Alzheimer's disease. Alzheimer's Research & Therapy. 5: 55. PMID 24499616 DOI: 10.1186/alzrt219 |
0.697 |
|
| 2013 |
Fernández D, Horrillo A, Alquezar C, González-Manchón C, Parrilla R, Ayuso MS. Control of cell adhesion and migration by podocalyxin. Implication of Rac1 and Cdc42. Biochemical and Biophysical Research Communications. 432: 302-7. PMID 23396057 DOI: 10.1016/j.bbrc.2013.01.112 |
0.733 |
|
| 2013 |
Esteras N, Alquézar C, Bermejo-Pareja F, Bialopiotrowicz E, Wojda U, Martín-Requero A. Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients. Neurobiology of Aging. 34: 1090-100. PMID 23153928 DOI: 10.1016/j.neurobiolaging.2012.10.014 |
0.727 |
|
| 2012 |
Esteras N, Bartolomé F, Alquézar C, Antequera D, Muñoz Ú, Carro E, Martín-Requero Á. Altered cell cycle-related gene expression in brain and lymphocytes from a transgenic mouse model of Alzheimer's disease [amyloid precursor protein/presenilin 1 (PS1)]. The European Journal of Neuroscience. 36: 2609-18. PMID 22702220 DOI: 10.1111/j.1460-9568.2012.08178.x |
0.727 |
|
| 2012 |
Alquezar C, Esteras N, Alzualde A, Moreno F, Ayuso MS, López de Munain A, Martín-Requero Á. Inactivation of CDK/pRb pathway normalizes survival pattern of lymphoblasts expressing the FTLD-progranulin mutation c.709-1G>A. Plos One. 7: e37057. PMID 22623979 DOI: 10.1371/journal.pone.0037057 |
0.686 |
|
| 2012 |
Esteras N, Alquézar C, Bartolomé F, Antequera D, Barrios L, Carro E, Cerdán S, Martín-Requero A. Systematic evaluation of magnetic resonance imaging and spectroscopy techniques for imaging a transgenic model of Alzheimer's disease (AβPP/PS1). Journal of Alzheimer's Disease : Jad. 30: 337-53. PMID 22406445 DOI: 10.3233/Jad-2012-111967 |
0.63 |
|
| 2012 |
Esteras N, Muñoz Ú, Alquézar C, Bartolomé F, Bermejo-Pareja F, Martín-Requero Á. Altered calmodulin degradation and signaling in non-neuronal cells from Alzheimer's disease patients. Current Alzheimer Research. 9: 267-77. PMID 22044025 DOI: 10.2174/156720512800107564 |
0.715 |
|
| 2012 |
Alquezar C, Esteras N, Bartolomé F, Merino JJ, Alzualde A, López de Munain A, Martín-Requero Á. Alteration in cell cycle-related proteins in lymphoblasts from carriers of the c.709-1G>A PGRN mutation associated with FTLD-TDP dementia. Neurobiology of Aging. 33: 429.e7-20. PMID 21232819 DOI: 10.1016/j.neurobiolaging.2010.11.020 |
0.716 |
|
| 2010 |
Bartolomé F, Muñoz U, Esteras N, Alquezar C, Collado A, Bermejo-Pareja F, Martín-Requero A. Simvastatin overcomes the resistance to serum withdrawal-induced apoptosis of lymphocytes from Alzheimer's disease patients. Cellular and Molecular Life Sciences : Cmls. 67: 4257-68. PMID 20614159 DOI: 10.1007/s00018-010-0443-2 |
0.729 |
|
| 2010 |
de las Cuevas N, Muñoz Ú, Bartolomé F, Esteras N, Alquezar C, Martín-Requero Á. Cell cycle and Alzheimer's disease: studies in non-neuronal cells Journal of Applied Biomedicine. 8: 121-130. DOI: 10.2478/V10136-009-0015-7 |
0.34 |
|
| Show low-probability matches. |