Esteban Domingo - Publications

Affiliations: 
Virology Severo Ochoa Center for Molecular Biology, Universidad Autónoma de Madrid, Madrid, Comunidad de Madrid, Spain 

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Year Citation  Score
2024 Martínez-González B, Soria ME, Mínguez P, Lorenzo-Redondo R, Salar-Vidal L, López-García A, Esteban-Muñoz M, Durán-Pastor A, Somovilla P, García-Crespo C, de Ávila AI, Gómez J, Esteban J, Fernández-Roblas R, Gadea I, ... Domingo E, et al. SARS-CoV-2 mutant spectra as variant of concern nurseries: endless variation? Frontiers in Microbiology. 15: 1358258. PMID 38559344 DOI: 10.3389/fmicb.2024.1358258  0.358
2024 Delgado S, Somovilla P, Ferrer-Orta C, Martínez-González B, Vázquez-Monteagudo S, Muñoz-Flores J, Soria ME, García-Crespo C, de Ávila AI, Durán-Pastor A, Gadea I, López-Galíndez C, Moran F, Lorenzo-Redondo R, Verdaguer N, ... ... Domingo E, et al. Incipient functional SARS-CoV-2 diversification identified through neural network haplotype maps. Proceedings of the National Academy of Sciences of the United States of America. 121: e2317851121. PMID 38416684 DOI: 10.1073/pnas.2317851121  0.365
2023 Domingo E, Martínez-González B, García-Crespo C, Somovilla P, de Ávila AI, Soria ME, Durán-Pastor A, Perales C. Puzzles, challenges, and information reservoir of SARS-CoV-2 quasispecies. Journal of Virology. 97: e0151123. PMID 38092661 DOI: 10.1128/jvi.01511-23  0.372
2023 Ariza-Mateos A, Briones C, Perales C, Bayo-Jiménez MT, Domingo E, Gómez J. Viruses as archaeological tools for uncovering ancient molecular relationships. Annals of the New York Academy of Sciences. PMID 37801367 DOI: 10.1111/nyas.15071  0.36
2023 Martínez-González B, Gallego I, Gregori J, Soria ME, Somovilla P, de Ávila AI, García-Crespo C, Durán-Pastor A, Briones C, Gómez J, Quer J, Domingo E, Perales C. Fitness-Dependent, Mild Mutagenic Activity of Sofosbuvir for Hepatitis C Virus. Antimicrobial Agents and Chemotherapy. 67: e0039423. PMID 37367486 DOI: 10.1128/aac.00394-23  0.303
2023 Somovilla P, García-Crespo C, Martínez-González B, Soria ME, de Ávila AI, Gallego I, Mínguez P, Durán-Pastor A, Ferrer-Orta C, Salar-Vidal L, Esteban-Muñoz M, Zuñiga S, Sola I, Enjuanes L, Esteban J, ... ... Domingo E, et al. Atypical Mutational Spectrum of SARS-CoV-2 Replicating in the Presence of Ribavirin. Antimicrobial Agents and Chemotherapy. 67: e0131522. PMID 36602354 DOI: 10.1128/aac.01315-22  0.559
2023 Domingo E, García-Crespo C, Soria ME, Perales C. Viral Fitness, Population Complexity, Host Interactions, and Resistance to Antiviral Agents. Current Topics in Microbiology and Immunology. 439: 197-235. PMID 36592247 DOI: 10.1007/978-3-031-15640-3_6  0.404
2022 Gregori J, Colomer-Castell S, Campos C, Ibañez-Lligoña M, Garcia-Cehic D, Rando-Segura A, Adombie CM, Pintó R, Guix S, Bosch A, Domingo E, Gallego I, Perales C, Cortese MF, Tabernero D, et al. Quasispecies Fitness Partition to Characterize the Molecular Status of a Viral Population. Negative Effect of Early Ribavirin Discontinuation in a Chronically Infected HEV Patient. International Journal of Molecular Sciences. 23. PMID 36498981 DOI: 10.3390/ijms232314654  0.353
2022 Ariza-Mateos A, Perales C, Domingo E, Gómez J. Application of archaeological concepts to the interpretation of RNA virus quasi species evolution. Theoretical Biology Forum. 115: 133-143. PMID 36325936 DOI: 10.19272/202211402009  0.443
2022 Martínez-González B, Soria ME, Vázquez-Sirvent L, Ferrer-Orta C, Lobo-Vega R, Mínguez P, de la Fuente L, Llorens C, Soriano B, Ramos-Ruíz R, Cortón M, López-Rodríguez R, García-Crespo C, Somovilla P, Durán-Pastor A, ... ... Domingo E, et al. SARS-CoV-2 Mutant Spectra at Different Depth Levels Reveal an Overwhelming Abundance of Low Frequency Mutations. Pathogens (Basel, Switzerland). 11. PMID 35745516 DOI: 10.3390/pathogens11060662  0.568
2022 Martínez-González B, Soria ME, Vázquez-Sirvent L, Ferrer-Orta C, Lobo-Vega R, Mínguez P, de la Fuente L, Llorens C, Soriano B, Ramos R, Cortón M, López-Rodríguez R, García-Crespo C, Gallego I, de Ávila AI, ... ... Domingo E, et al. SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes. Microbiology Spectrum. 10: e0022122. PMID 35348367 DOI: 10.1128/spectrum.00221-22  0.561
2022 Martínez-González B, Vázquez-Sirvent L, Soria ME, Mínguez P, Salar-Vidal L, García-Crespo C, Gallego I, Ávila A, Llorens C, Soriano B, Ramos-Ruiz R, Esteban J, Fernandez-Roblas R, Gadea I, Ayuso C, ... ... Domingo E, et al. Vaccine-breakthrough infections with SARS-CoV-2 Alpha mirror mutations in Delta Plus, Iota and Omicron. The Journal of Clinical Investigation. PMID 35259127 DOI: 10.1172/JCI157700  0.397
2022 Torres-Vázquez B, de Lucas AM, García-Crespo C, García-Martín JA, Fragoso A, Fernández-Algar M, Perales C, Domingo E, Moreno M, Briones C. In vitro Selection of High Affinity DNA and RNA Aptamers that Detect Hepatitis C Virus Core Protein of Genotypes 1 to 4 and Inhibit Virus Production in Cell Culture. Journal of Molecular Biology. 434: 167501. PMID 35183559 DOI: 10.1016/j.jmb.2022.167501  0.341
2022 Sabariegos R, Ortega-Prieto AM, Díaz-Martínez L, Grande-Pérez A, García Crespo C, Gallego I, de Ávila AI, Albentosa-González L, Soria ME, Gastaminza P, Domingo E, Perales C, Mas A. Guanosine inhibits hepatitis C virus replication and increases indel frequencies, associated with altered intracellular nucleotide pools. Plos Pathogens. 18: e1010210. PMID 35085375 DOI: 10.1371/journal.ppat.1010210  0.391
2021 Caridi F, Cañas-Arranz R, Vázquez-Calvo Á, de León P, Calderón KI, Domingo E, Sobrino F, Martín-Acebes MA. Adaptive value of foot-and-mouth disease virus capsid substitutions with opposite effects on particle acid stability. Scientific Reports. 11: 23494. PMID 34873184 DOI: 10.1038/s41598-021-02757-3  0.375
2021 Delgado S, Perales C, García-Crespo C, Soria ME, Gallego I, de Ávila AI, Martínez-González B, Vázquez-Sirvent L, López-Galíndez C, Morán F, Domingo E. A Two-Level, Intramutant Spectrum Haplotype Profile of Hepatitis C Virus Revealed by Self-Organized Maps. Microbiology Spectrum. e0145921. PMID 34756074 DOI: 10.1128/Spectrum.01459-21  0.437
2021 Sabariegos R, Albentosa-González L, Palmero B, Clemente-Casares P, Ramírez E, García-Crespo C, Gallego I, de Ávila AI, Perales C, Domingo E, Mas A. Akt Phosphorylation of Hepatitis C Virus NS5B Regulates Polymerase Activity and Hepatitis C Virus Infection. Frontiers in Microbiology. 12: 754664. PMID 34745059 DOI: 10.3389/fmicb.2021.754664  0.417
2021 Domingo E, García-Crespo C, Perales C. Historical Perspective on the Discovery of the Quasispecies Concept. Annual Review of Virology. 8: 51-72. PMID 34586874 DOI: 10.1146/annurev-virology-091919-105900  0.436
2021 Domingo E, García-Crespo C, Lobo-Vega R, Perales C. Mutation Rates, Mutation Frequencies, and Proofreading-Repair Activities in RNA Virus Genetics. Viruses. 13. PMID 34578463 DOI: 10.3390/v13091882  0.428
2021 García-Crespo C, Gallego I, Soria ME, de Ávila AI, Martínez-González B, Vázquez-Sirvent L, Lobo-Vega R, Moreno E, Gómez J, Briones C, Gregori J, Quer J, Domingo E, Perales C. Population Disequilibrium as Promoter of Adaptive Explorations in Hepatitis C Virus. Viruses. 13. PMID 33916702 DOI: 10.3390/v13040616  0.481
2021 Domingo E. Quasispecies Theory in Virology. Journal of Virology. 76: 463-465. PMID 33739796 DOI: 10.1128/JVI.76.1.463-465.2002  0.344
2020 García-Crespo C, Soria ME, Gallego I, Ávila AI, Martínez-González B, Vázquez-Sirvent L, Gómez J, Briones C, Gregori J, Quer J, Perales C, Domingo E. Dissimilar Conservation Pattern in Hepatitis C Virus Mutant Spectra, Consensus Sequences, and Data Banks. Journal of Clinical Medicine. 9. PMID 33121037 DOI: 10.3390/jcm9113450  0.467
2020 Soria ME, García-Crespo C, Martínez-Gónzalez B, Vázquez-Sirvent L, Lobo-Vega R, de Ávila AI, Gallego I, Chen Q, García-Cehic D, Llorens-Revull M, Briones C, Gómez J, Ferrer-Orta C, Verdaguer N, Gregori J, ... ... Domingo E, et al. Amino acid substitutions associated with treatment failure of hepatitis C virus infection. Journal of Clinical Microbiology. PMID 32999010 DOI: 10.1128/JCM.01985-20  0.335
2020 Domingo E, Soria ME, Gallego I, de Ávila AI, García-Crespo C, Martínez-González B, Gómez J, Briones C, Gregori J, Quer J, Perales C. A new implication of quasispecies dynamics: Broad virus diversification in absence of external perturbations. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 104278. PMID 32165244 DOI: 10.1016/J.Meegid.2020.104278  0.442
2019 Gallego I, Soria ME, García-Crespo C, Chen Q, Martínez-Barragán P, Khalfaoui S, Martínez-González B, Sanchez-Martin I, Palacios-Blanco I, de Ávila AI, García-Cehic D, Esteban JI, Gómez J, Briones C, Gregori J, ... ... Domingo E, et al. Broad and dynamic diversification of infectious hepatitis C virus in a cell culture environment. Journal of Virology. PMID 31852791 DOI: 10.1128/Jvi.01856-19  0.519
2019 Domingo E, Perales C. Viral quasispecies. Plos Genetics. 15: e1008271. PMID 31622336 DOI: 10.1371/journal.pgen.1008271  0.52
2019 Gallego I, Soria ME, Gregori J, de Ávila AI, García-Crespo C, Moreno E, Gadea I, Esteban J, Fernández-Roblas R, Esteban JI, Gómez J, Quer J, Domingo E, Perales C. Synergistic lethal mutagenesis of hepatitis C virus. Antimicrobial Agents and Chemotherapy. PMID 31570400 DOI: 10.1128/Aac.01653-19  0.437
2019 Borrego B, de Ávila AI, Domingo E, Brun A. Lethal Mutagenesis of Rift Valley Fever Virus Induced by Favipiravir. Antimicrobial Agents and Chemotherapy. 63. PMID 31085519 DOI: 10.1128/AAC.00669-19  0.345
2019 Domingo E, Ávila AId, Gallego I, Sheldon J, Perales C. Viral fitness: history and relevance for viral pathogenesis and antiviral interventions. Pathogens and Disease. 77. PMID 30980658 DOI: 10.1093/Femspd/Ftz021  0.423
2019 Altan-Bonnet N, Perales C, Domingo E. Extracellular vesicles: Vehicles of en bloc viral transmission Virus Research. 265: 143-149. PMID 30928427 DOI: 10.1016/J.Virusres.2019.03.023  0.362
2018 Gregori J, Soria ME, Gallego I, Guerrero-Murillo M, Esteban JI, Quer J, Perales C, Domingo E. Rare haplotype load as marker for lethal mutagenesis. Plos One. 13. PMID 30281674 DOI: 10.1371/Journal.Pone.0204877  0.534
2018 Gallego I, Gregori J, Soria ME, García-Crespo C, García-Álvarez M, Gómez-González A, Valiergue R, Gómez J, Esteban JI, Quer J, Domingo E, Perales C. Resistance of high fitness hepatitis C virus to lethal mutagenesis. Virology. 523: 100-109. PMID 30107298 DOI: 10.1016/J.Virol.2018.07.030  0.457
2018 de la Higuera I, Ferrer-Orta C, Moreno E, de Ávila AI, Soria ME, Singh K, Caridi F, Sobrino F, Sarafianos SG, Perales C, Verdaguer N, Domingo E. Contribution of a multifunctional polymerase region of foot-and-mouth disease virus to lethal mutagenesis. Journal of Virology. PMID 30068642 DOI: 10.1128/Jvi.01119-18  0.461
2018 Domingo E, Perales C. Quasispecies and virus. European Biophysics Journal : Ebj. PMID 29397419 DOI: 10.1007/S00249-018-1282-6  0.471
2017 Escribano-Romero E, Jiménez de Oya N, Domingo E, Saiz JC. Extinction of West Nile Virus by Favipiravir through Lethal Mutagenesis. Antimicrobial Agents and Chemotherapy. 61. PMID 28848019 DOI: 10.1128/AAC.01400-17  0.392
2017 de la Higuera I, Ferrer-Orta C, de Ávila AI, Perales C, Sierra M, Singh K, Sarafianos SG, Dehouck Y, Bastolla U, Verdaguer N, Domingo E. Molecular and functional bases of selection against a mutation bias in an RNA virus. Genome Biology and Evolution. PMID 28460010 DOI: 10.1093/Gbe/Evx075  0.539
2017 de Avila AI, Moreno E, Perales C, Domingo E. Favipiravir can evoke lethal mutagenesis and extinction of foot-and-mouth disease virus. Virus Research. PMID 28322918 DOI: 10.1016/J.Virusres.2017.03.014  0.428
2017 Moreno E, Gallego I, Gregori J, Lucía-Sanz A, Soria ME, Castro V, Beach NM, Manrubia SC, Quer J, Esteban JI, Rice CM, Gómez J, Gastaminza P, Domingo E, Perales C. Internal disequilibria and phenotypic diversification during replication of hepatitis C virus in a non-coevolving cellular environment. Journal of Virology. PMID 28275194 DOI: 10.1128/Jvi.02505-16  0.435
2017 Quer J, Rodríguez-Frias F, Gregori J, Tabernero D, Soria ME, García-Cehic D, Homs M, Bosch A, Pintó RM, Esteban JI, Domingo E, Perales C. Deep sequencing in the management of hepatitis virus infections Virus Research. 239: 115-125. PMID 28040474 DOI: 10.1016/J.Virusres.2016.12.020  0.401
2016 de Ávila AI, Gallego I, Soria ME, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C. Lethal Mutagenesis of Hepatitis C Virus Induced by Favipiravir. Plos One. 11: e0164691. PMID 27755573 DOI: 10.1371/Journal.Pone.0164691  0.343
2016 Agudo R, de la Higuera I, Arias A, Grande-Pérez A, Domingo E. Involvement of a joker mutation in a polymerase-independent lethal mutagenesis escape mechanism. Virology. 494: 257-66. PMID 27136067 DOI: 10.1016/j.virol.2016.04.023  0.385
2016 Gallego I, Sheldon J, Moreno E, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C. Barrier-Independent, Fitness-Associated Differences in Sofosbuvir Efficacy against Hepatitis C Virus. Antimicrobial Agents and Chemotherapy. 60: 3786-93. PMID 27067341 DOI: 10.1128/Aac.00581-16  0.365
2016 Gregori J, Perales C, Rodriguez-Frias F, Esteban JI, Quer J, Domingo E. Viral quasispecies complexity measures Virology. 493: 227-237. PMID 27060566 DOI: 10.1016/J.Virol.2016.03.017  0.389
2015 Perales C, Quer J, Gregori JM, Esteban JI, Domingo E. Resistance of Hepatitis C Virus to Inhibitors: Complexity and Clinical Implications. Viruses. 7: 5746-5766. PMID 26561827 DOI: 10.3390/V7112902  0.317
2015 Perales C, Domingo E. Antiviral Strategies Based on Lethal Mutagenesis and Error Threshold. Current Topics in Microbiology and Immunology. 392: 323-339. PMID 26294225 DOI: 10.1007/82_2015_459  0.369
2015 Perales C, Moreno E, Domingo E. Clonality and intracellular polyploidy in virus evolution and pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 112: 8887-92. PMID 26195777 DOI: 10.1073/Pnas.1501715112  0.421
2015 Ferrer-Orta C, de la Higuera I, Caridi F, Sánchez-Aparicio MT, Moreno E, Perales C, Singh K, Sarafianos SG, Sobrino F, Domingo E, Verdaguer N. Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition. Journal of Virology. 89: 6848-59. PMID 25903341 DOI: 10.1128/Jvi.03283-14  0.303
2015 Andino R, Domingo E. Viral quasispecies. Virology. 479: 46-51. PMID 25824477 DOI: 10.1016/j.virol.2015.03.022  0.499
2014 Sheldon J, Beach NM, Moreno E, Gallego I, Piñeiro D, Martínez-Salas E, Gregori J, Quer J, Esteban JI, Rice CM, Domingo E, Perales C. Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus. Journal of Virology. 88: 12098-111. PMID 25122776 DOI: 10.1128/Jvi.01860-14  0.379
2014 Perales C, Beach NM, Sheldon J, Domingo E. Molecular basis of interferon resistance in hepatitis C virus. Current Opinion in Virology. 8: 38-44. PMID 24968186 DOI: 10.1016/J.Coviro.2014.05.003  0.363
2014 Moreno E, Ojosnegros S, García-Arriaza J, Escarmís C, Domingo E, Perales C. Exploration of sequence space as the basis of viral RNA genome segmentation. Proceedings of the National Academy of Sciences of the United States of America. 111: 6678-83. PMID 24757055 DOI: 10.1073/Pnas.1323136111  0.363
2013 Gregori J, Esteban JI, Cubero M, Garcia-Cehic D, Perales C, Casillas R, Alvarez-Tejado M, Rodríguez-Frías F, Guardia J, Domingo E, Quer J. Ultra-deep pyrosequencing (UDPS) data treatment to study amplicon HCV minor variants Plos One. 8. PMID 24391758 DOI: 10.1371/Journal.Pone.0083361  0.405
2013 Ortega-Prieto AM, Sheldon J, Grande-Pérez A, Tejero H, Gregori J, Quer J, Esteban JI, Domingo E, Perales C. Extinction of Hepatitis C Virus by Ribavirin in Hepatoma Cells Involves Lethal Mutagenesis Plos One. 8. PMID 23976977 DOI: 10.1371/Journal.Pone.0071039  0.379
2013 Ramezani F, Norouzi M, Sarizade GR, Poortahmasebi V, Kalantar E, Magnius L, Norder H, Domingo E, Jazayeri SM. Mutation hot spots in hepatitis B surface antigen in chronic carriers from Khoozestan province, southern of Iran. Iranian Journal of Allergy, Asthma, and Immunology. 12: 269-75. PMID 23893811  0.382
2013 Perales C, Beach NM, Gallego I, Soria ME, Quer J, Esteban JI, Rice C, Domingo E, Sheldon J. Response of hepatitis C virus to long-term passage in the presence of alpha interferon: multiple mutations and a common phenotype. Journal of Virology. 87: 7593-607. PMID 23637397 DOI: 10.1128/Jvi.02824-12  0.304
2013 Arias A, Isabel de Ávila A, Sanz-Ramos M, Agudo R, Escarmís C, Domingo E. Molecular dissection of a viral quasispecies under mutagenic treatment: positive correlation between fitness loss and mutational load. The Journal of General Virology. 94: 817-830. PMID 23239576 DOI: 10.1099/vir.0.049171-0  0.501
2013 Jaramillo N, Domingo E, Muñoz-Egea MC, Tabarés E, Gadea I. Evidence of Muller's ratchet in herpes simplex virus type 1. The Journal of General Virology. 94: 366-375. PMID 23100362 DOI: 10.1099/vir.0.044685-0  0.411
2012 Moreno H, Grande-Pérez A, Domingo E, Martín V. Arenaviruses and lethal mutagenesis. Prospects for new ribavirin-based interventions. Viruses. 4: 2786-805. PMID 23202505 DOI: 10.3390/v4112786  0.31
2012 Domingo E, Sheldon J, Perales C. Viral Quasispecies Evolution Microbiology and Molecular Biology Reviews. 76: 159-216. PMID 22688811 DOI: 10.1128/Mmbr.05023-11  0.451
2012 Moreno H, Tejero H, de la Torre JC, Domingo E, Martín V. Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection. Plos One. 7: e32550. PMID 22442668 DOI: 10.1371/journal.pone.0032550  0.43
2011 Simmonds P, Domingo E. Virus evolution. Current Opinion in Virology. 1: 410-2. PMID 22440843 DOI: 10.1016/j.coviro.2011.10.021  0.317
2011 Domingo E. Paradoxical interplay of viral and cellular functions. Viruses. 3: 272-7. PMID 21994731 DOI: 10.3390/v3030272  0.355
2011 Ojosnegros S, Perales C, Mas A, Domingo E. Quasispecies as a matter of fact: viruses and beyond. Virus Research. 162: 203-15. PMID 21945638 DOI: 10.1016/J.Virusres.2011.09.018  0.331
2011 Perales C, Henry M, Domingo E, Wain-Hobson S, Vartanian J. Lethal Mutagenesis of Foot-and-Mouth Disease Virus Involves Shifts in Sequence Space Journal of Virology. 85: 12227-12240. PMID 21917974 DOI: 10.1128/Jvi.00716-11  0.502
2011 Perales C, Agudo R, Manrubia SC, Domingo E. Influence of mutagenesis and viral load on the sustained low-level replication of an RNA virus. Journal of Molecular Biology. 407: 60-78. PMID 21256131 DOI: 10.1016/J.Jmb.2011.01.026  0.43
2010 Agudo R, Ferrer-Orta C, Arias A, Higuera Idl, Perales C, Pérez-Luque R, Verdaguer N, Domingo E. A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape Plos Pathogens. 6. PMID 20865120 DOI: 10.1371/Journal.Ppat.1001072  0.498
2010 Ojosnegros S, Beerenwinkel N, Domingo E. Competition-colonization dynamics: An ecology approach to quasispecies dynamics and virulence evolution in RNA viruses. Communicative & Integrative Biology. 3: 333-6. PMID 20798818 DOI: 10.4161/Cib.3.4.11658  0.317
2010 Arias A, Perales C, Escarmís C, Domingo E. Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus. Plos One. 5. PMID 20505767 DOI: 10.1371/Journal.Pone.0010735  0.451
2010 Manrubia SC, Domingo E, Lázaro E. Pathways to extinction: beyond the error threshold. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 365: 1943-52. PMID 20478889 DOI: 10.1098/rstb.2010.0076  0.438
2010 Domingo E. Mechanisms of viral emergence. Veterinary Research. 41: 38. PMID 20167200 DOI: 10.1051/vetres/2010010  0.377
2010 Ojosnegros S, Beerenwinkel N, Antal T, Nowak MA, Escarmís C, Domingo E. Competition-colonization dynamics in an RNA virus. Proceedings of the National Academy of Sciences of the United States of America. 107: 2108-12. PMID 20080701 DOI: 10.1073/Pnas.0909787107  0.379
2010 Martín V, Abia D, Domingo E, Grande-Pérez A. An interfering activity against lymphocytic choriomeningitis virus replication associated with enhanced mutagenesis. The Journal of General Virology. 91: 990-1003. PMID 20007356 DOI: 10.1099/vir.0.017053-0  0.392
2009 Agudo R, Arias A, Domingo E. 5-fluorouracil in lethal mutagenesis of foot-and-mouth disease virus. Future Medicinal Chemistry. 1: 529-39. PMID 21426129 DOI: 10.4155/fmc.09.26  0.478
2009 Perales C, Agudo R, Tejero H, Manrubia SC, Domingo E. Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections. Plos Pathogens. 5. PMID 19911056 DOI: 10.1371/Journal.Ppat.1000658  0.382
2009 Escarmís C, Perales C, Domingo E. Biological Effect of Muller's Ratchet: Distant Capsid Site Can Affect Picornavirus Protein Processing Journal of Virology. 83: 6748-6756. PMID 19403672 DOI: 10.1128/Jvi.00538-09  0.332
2008 Cases-González C, Arribas M, Domingo E, Lázaro E. Beneficial Effects of Population Bottlenecks in an RNA Virus Evolving at Increased Error Rate Journal of Molecular Biology. 384: 1120-1129. PMID 18951905 DOI: 10.1016/j.jmb.2008.10.014  0.377
2008 Arias A, Arnold JJ, Sierra M, Smidansky ED, Domingo E, Cameron CE. Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin. Journal of Virology. 82: 12346-55. PMID 18829745 DOI: 10.1128/Jvi.01297-08  0.39
2008 Domingo E, Grande-Pérez A, Martín V. Future prospects for the treatment of rapidly evolving viral pathogens: insights from evolutionary biology. Expert Opinion On Biological Therapy. 8: 1455-60. PMID 18774914 DOI: 10.1517/14712598.8.10.1455  0.378
2008 Sanz-Ramos M, Díaz-San Segundo F, Escarmís C, Domingo E, Sevilla N. Hidden virulence determinants in a viral quasispecies in vivo. Journal of Virology. 82: 10465-76. PMID 18715925 DOI: 10.1128/JVI.00825-08  0.455
2008 Agudo R, Arias A, Pariente N, Perales C, Escarmís C, Jorge A, Marina A, Domingo E. Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis. Journal of Molecular Biology. 382: 652-666. PMID 18662697 DOI: 10.1016/J.Jmb.2008.07.033  0.42
2008 Briones C, Domingo E. Minority report: hidden memory genomes in HIV-1 quasispecies and possible clinical implications. Aids Reviews. 10: 93-109. PMID 18615120  0.345
2008 Martín V, Grande-Pérez A, Domingo E. No evidence of selection for mutational robustness during lethal mutagenesis of lymphocytic choriomeningitis virus. Virology. 378: 185-92. PMID 18572218 DOI: 10.1016/j.virol.2008.05.016  0.485
2008 Martín V, Domingo E. Influence of the mutant spectrum in viral evolution: focused selection of antigenic variants in a reconstructed viral quasispecies. Molecular Biology and Evolution. 25: 1544-54. PMID 18436553 DOI: 10.1093/molbev/msn099  0.387
2008 Escarmís C, Lázaro E, Arias A, Domingo E. Repeated bottleneck transfers can lead to non-cytocidal forms of a cytopathic virus: implications for viral extinction. Journal of Molecular Biology. 376: 367-79. PMID 18158159 DOI: 10.1016/j.jmb.2007.11.042  0.469
2008 Herrera M, Grande-Pérez A, Perales C, Domingo E. Persistence of foot-and-mouth disease virus in cell culture revisited : implications for contingency in evolution Journal of General Virology. 89: 232-244. PMID 18089747 DOI: 10.1099/Vir.0.83312-0  0.305
2007 García-Arriaza J, Domingo E, Briones C. Characterization of minority subpopulations in the mutant spectrum of HIV-1 quasispecies by successive specific amplifications. Virus Research. 129: 123-34. PMID 17706828 DOI: 10.1016/j.virusres.2007.07.001  0.341
2007 Núñez JI, Molina N, Baranowski E, Domingo E, Clark S, Burman A, Berryman S, Jackson T, Sobrino F. Guinea pig-adapted foot-and-mouth disease virus with altered receptor recognition can productively infect a natural host. Journal of Virology. 81: 8497-506. PMID 17522230 DOI: 10.1128/JVI.00340-07  0.313
2007 Ferrer-Orta C, Arias A, Pérez-Luque R, Escarmís C, Domingo E, Verdaguer N. Sequential structures provide insights into the fidelity of RNA replication. Proceedings of the National Academy of Sciences of the United States of America. 104: 9463-8. PMID 17517631 DOI: 10.1073/pnas.0700518104  0.362
2007 Perales C, Mateo R, Mateu MG, Domingo E. Insights into RNA Virus Mutant Spectrum and Lethal Mutagenesis Events: Replicative Interference and Complementation by Multiple Point Mutants Journal of Molecular Biology. 369: 985-1000. PMID 17481660 DOI: 10.1016/J.Jmb.2007.03.074  0.461
2007 Herrera M, García-Arriaza J, Pariente N, Escarmís C, Domingo E. Molecular basis for a lack of correlation between viral fitness and cell killing capacity. Plos Pathogens. 3: e53. PMID 17432933 DOI: 10.1371/journal.ppat.0030053  0.424
2007 Domingo E, Gomez J. Quasispecies and its impact on viral hepatitis. Virus Research. 127: 131-50. PMID 17349710 DOI: 10.1016/j.virusres.2007.02.001  0.441
2006 Martín V, Perales C, Dávila M, Domingo E. Viral fitness can influence the repertoire of virus variants selected by antibodies. Journal of Molecular Biology. 362: 44-54. PMID 16890952 DOI: 10.1016/J.Jmb.2006.06.077  0.373
2006 García-Arriaza J, Ojosnegros S, Dávila M, Domingo E, Escarmís C. Dynamics of mutation and recombination in a replicating population of complementing, defective viral genomes. Journal of Molecular Biology. 360: 558-72. PMID 16797586 DOI: 10.1016/j.jmb.2006.05.027  0.426
2006 Martín V, Perales C, Abia D, Ortíz AR, Domingo E, Briones C. Microarray-based identification of antigenic variants of foot-and-mouth disease virus: a bioinformatics quality assessment Bmc Genomics. 7: 117-117. PMID 16709242 DOI: 10.1186/1471-2164-7-117  0.326
2006 Costa-Mattioli M, Domingo E, Cristina J. Analysis of sequential hepatitis A virus strains reveals coexistence of distinct viral subpopulations. The Journal of General Virology. 87: 115-8. PMID 16361423 DOI: 10.1099/Vir.0.81286-0  0.323
2005 Greene IP, Wang E, Deardorff ER, Milleron R, Domingo E, Weaver SC. Effect of alternating passage on adaptation of sindbis virus to vertebrate and invertebrate cells. Journal of Virology. 79: 14253-60. PMID 16254360 DOI: 10.1128/Jvi.79.22.14253-14260.2005  0.427
2005 Arias A, Agudo R, Ferrer-Orta C, Pérez-Luque R, Airaksinen A, Brocchi E, Domingo E, Verdaguer N, Escarmís C. Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding. Journal of Molecular Biology. 353: 1021-32. PMID 16216271 DOI: 10.1016/j.jmb.2005.09.022  0.381
2005 Grande-Pérez A, Gómez-Mariano G, Lowenstein PR, Domingo E. Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence. Journal of Virology. 79: 10451-9. PMID 16051837 DOI: 10.1128/Jvi.79.16.10451-10459.2005  0.398
2005 González-López C, Gómez-Mariano G, Escarmís C, Domingo E. Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 5: 366-74. PMID 16002345 DOI: 10.1016/j.meegid.2005.05.001  0.459
2005 García-Arriaza J, Domingo E, Escarmís C. A segmented form of foot-and-mouth disease virus interferes with standard virus: a link between interference and competitive fitness. Virology. 335: 155-64. PMID 15840515 DOI: 10.1016/j.virol.2005.02.012  0.411
2005 Yuste E, Bordería AV, Domingo E, López-Galíndez C. Few mutations in the 5' leader region mediate fitness recovery of debilitated human immunodeficiency type 1 viruses. Journal of Virology. 79: 5421-7. PMID 15827156 DOI: 10.1128/JVI.79.9.5421-5427.2005  0.469
2005 Manrubia SC, Escarmís C, Domingo E, Lázaro E. High mutation rates, bottlenecks, and robustness of RNA viral quasispecies. Gene. 347: 273-82. PMID 15777632 DOI: 10.1016/j.gene.2004.12.033  0.403
2005 Grande-Pérez A, Lázaro E, Lowenstein P, Domingo E, Manrubia SC. Suppression of viral infectivity through lethal defection. Proceedings of the National Academy of Sciences of the United States of America. 102: 4448-52. PMID 15767582 DOI: 10.1073/Pnas.0408871102  0.399
2005 Domingo E, Escarmís C, Lázaro E, Manrubia SC. Quasispecies dynamics and RNA virus extinction. Virus Research. 107: 129-39. PMID 15649559 DOI: 10.1016/j.virusres.2004.11.003  0.465
2005 Perales C, Martín V, Ruiz-Jarabo CM, Domingo E. Monitoring sequence space as a test for the target of selection in viruses. Journal of Molecular Biology. 345: 451-459. PMID 15581890 DOI: 10.1016/J.Jmb.2004.10.066  0.412
2004 García-Arriaza J, Manrubia SC, Toja M, Domingo E, Escarmís C. Evolutionary transition toward defective RNAs that are infectious by complementation. Journal of Virology. 78: 11678-85. PMID 15479809 DOI: 10.1128/JVI.78.21.11678-11685.2004  0.345
2004 Ferrer-Orta C, Arias A, Perez-Luque R, Escarmís C, Domingo E, Verdaguer N. Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA. The Journal of Biological Chemistry. 279: 47212-21. PMID 15294895 DOI: 10.1074/jbc.M405465200  0.317
2004 Ruiz-Jarabo CM, Pariente N, Baranowski E, Dávila M, Gómez-Mariano G, Domingo E. Expansion of host-cell tropism of foot-and-mouth disease virus despite replication in a constant environment. The Journal of General Virology. 85: 2289-2297. PMID 15269370 DOI: 10.1099/vir.0.80126-0  0.371
2004 Pariente N, Pernas M, de la Rosa R, Gómez-Mariano G, Fernández G, Rubio A, López M, Benito JM, López-Galíndez C, Leal M, Domingo E, Martinez MA, Mas A. Long-term suppression of plasma viremia with highly active antiretroviral therapy despite virus evolution and very limited selection of drug-resistant genotypes. Journal of Medical Virology. 73: 350-61. PMID 15170628 DOI: 10.1002/jmv.20098  0.343
2004 González-López C, Arias A, Pariente N, Gómez-Mariano G, Domingo E. Preextinction viral RNA can interfere with infectivity. Journal of Virology. 78: 3319-24. PMID 15016853 DOI: 10.1128/jvi.78.7.3319-3324.2004  0.379
2003 Sánchez G, Bosch A, Gómez-Mariano G, Domingo E, Pintó RM. Evidence for quasispecies distributions in the human hepatitis A virus genome. Virology. 315: 34-42. PMID 14592757  0.504
2003 Lázaro E, Escarmís C, Pérez-Mercader J, Manrubia SC, Domingo E. Resistance of virus to extinction on bottleneck passages: study of a decaying and fluctuating pattern of fitness loss. Proceedings of the National Academy of Sciences of the United States of America. 100: 10830-5. PMID 12960384 DOI: 10.1073/pnas.1332668100  0.448
2003 Airaksinen A, Pariente N, Menéndez-Arias L, Domingo E. Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis. Virology. 311: 339-49. PMID 12842623 DOI: 10.1016/s0042-6822(03)00144-2  0.497
2003 Domingo E. Quasispecies and the development of new antiviral strategies. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. Progres Des Recherches Pharmaceutiques. 60: 133-58. PMID 12790341 DOI: 10.1007/978-3-0348-8012-1_4  0.435
2003 Pariente N, Airaksinen A, Domingo E. Mutagenesis versus inhibition in the efficiency of extinction of foot-and-mouth disease virus. Journal of Virology. 77: 7131-8. PMID 12768034 DOI: 10.1128/jvi.77.12.7131-7138.2003  0.462
2003 Ruiz-Jarabo CM, Ly C, Domingo E, de la Torre JC. Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV). Virology. 308: 37-47. PMID 12706088 DOI: 10.1016/S0042-6822(02)00046-6  0.467
2003 Domingo E, Escarmís C, Baranowski E, Ruiz-Jarabo CM, Carrillo E, Núñez JI, Sobrino F. Evolution of foot-and-mouth disease virus. Virus Research. 91: 47-63. PMID 12527437 DOI: 10.1016/s0168-1702(02)00259-9  0.429
2003 Tami C, Taboga O, Berinstein A, Núñez JI, Palma EL, Domingo E, Sobrino F, Carrillo E. Evidence of the coevolution of antigenicity and host cell tropism of foot-and-mouth disease virus in vivo. Journal of Virology. 77: 1219-26. PMID 12502839  0.369
2003 Domingo E, Baranowski E, Escarmís C, Sobrino F. Foot-and-mouth disease virus. Comparative Immunology, Microbiology and Infectious Diseases. 25: 297-308. PMID 12365806 DOI: 10.1016/s0147-9571(02)00027-9  0.323
2002 Quiñones-Mateu ME, Tadele M, Parera M, Mas A, Weber J, Rangel HR, Chakraborty B, Clotet B, Domingo E, Menéndez-Arias L, Martínez MA. Insertions in the reverse transcriptase increase both drug resistance and viral fitness in a human immunodeficiency virus type 1 isolate harboring the multi-nucleoside reverse transcriptase inhibitor resistance 69 insertion complex mutation. Journal of Virology. 76: 10546-52. PMID 12239335  0.46
2002 Lázaro E, Escarmís C, Domingo E, Manrubia SC. Modeling viral genome fitness evolution associated with serial bottleneck events: evidence of stationary states of fitness. Journal of Virology. 76: 8675-81. PMID 12163587 DOI: 10.1128/jvi.76.17.8675-8681.2002  0.306
2002 Escarmís C, Gómez-Mariano G, Dávila M, Lázaro E, Domingo E. Resistance to extinction of low fitness virus subjected to plaque-to-plaque transfers: diversification by mutation clustering. Journal of Molecular Biology. 315: 647-61. PMID 11812137 DOI: 10.1006/jmbi.2001.5259  0.432
2001 Arias A, Lázaro E, Escarmís C, Domingo E. Molecular intermediates of fitness gain of an RNA virus: characterization of a mutant spectrum by biological and molecular cloning. The Journal of General Virology. 82: 1049-1060. PMID 11297679 DOI: 10.1099/0022-1317-82-5-1049  0.554
1998 Elena SF, Dávila M, Novella IS, Holland JJ, Domingo E, Moya A. EVOLUTIONARY DYNAMICS OF FITNESS RECOVERY FROM THE DEBILITATING EFFECTS OF MULLER'S RATCHET. Evolution; International Journal of Organic Evolution. 52: 309-314. PMID 28568345 DOI: 10.1111/J.1558-5646.1998.Tb01633.X  0.365
Low-probability matches (unlikely to be authored by this person)
2012 Sánchez-Jiménez C, Olivares I, de Ávila Lucas AI, Toledano V, Gutiérrez-Rivas M, Lorenzo-Redondo R, Grande-Pérez A, Domingo E, López-Galíndez C. Mutagen-mediated enhancement of HIV-1 replication in persistently infected cells. Virology. 424: 147-53. PMID 22265575 DOI: 10.1016/j.virol.2011.12.016  0.299
2018 Perales C, Chen Q, Soria ME, Gregori J, Garcia-Cehic D, Nieto-Aponte L, Castells L, Imaz A, Llorens-Revull M, Domingo E, Buti M, Esteban JI, Rodriguez-Frias F, Quer J. Baseline hepatitis C virus resistance-associated substitutions present at frequencies lower than 15% may be clinically significant. Infection and Drug Resistance. 11: 2207-2210. PMID 30519058 DOI: 10.2147/Idr.S172226  0.298
2022 García-Crespo C, Vázquez-Sirvent L, Somovilla P, Soria ME, Gallego I, de Ávila AI, Martínez-González B, Durán-Pastor A, Domingo E, Perales C. Efficacy decrease of antiviral agents when administered to ongoing hepatitis C virus infections in cell culture. Frontiers in Microbiology. 13: 960676. PMID 35992670 DOI: 10.3389/fmicb.2022.960676  0.298
2011 Moreno H, Gallego I, Sevilla N, de la Torre JC, Domingo E, Martín V. Ribavirin can be mutagenic for arenaviruses. Journal of Virology. 85: 7246-55. PMID 21561907 DOI: 10.1128/JVI.00614-11  0.296
2011 Iranzo J, Perales C, Domingo E, Manrubia SC. Tempo and mode of inhibitor–mutagen antiviral therapies: A multidisciplinary approach Proceedings of the National Academy of Sciences of the United States of America. 108: 16008-16013. PMID 21911373 DOI: 10.1073/Pnas.1110489108  0.296
2016 Valero ML, Sabariegos R, Cimas FJ, Perales C, Domingo E, Sánchez-Prieto R, Mas A. Hepatitis C Virus RNA-Dependent RNA Polymerase Interacts with the Akt/PKB Kinase and Induces Its Subcellular Relocalization Antimicrobial Agents and Chemotherapy. 60: 3540-3550. PMID 27021315 DOI: 10.1128/Aac.03019-15  0.295
2014 Cubero M, Gregori J, Esteban JI, García-Cehic D, Bes M, Perales C, Domingo E, Rodríguez-Frías F, Sauleda S, Casillas R, Sanchez A, Ortega I, Esteban R, Guardia J, Quer J. Identification of host and viral factors involved in a dissimilar resolution of a hepatitis C virus infection. Liver International : Official Journal of the International Association For the Study of the Liver. 34: 896-906. PMID 24134179 DOI: 10.1111/Liv.12362  0.294
2018 Soria ME, Gregori J, Chen Q, García-Cehic D, Llorens M, de Ávila AI, Beach NM, Domingo E, Rodríguez-Frías F, Buti M, Esteban R, Esteban JI, Quer J, Perales C. Pipeline for specific subtype amplification and drug resistance detection in hepatitis C virus. Bmc Infectious Diseases. 18: 446. PMID 30176817 DOI: 10.1186/S12879-018-3356-6  0.293
2009 Ferrer-Orta C, Agudo R, Domingo E, Verdaguer N. Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase. Current Opinion in Structural Biology. 19: 752-8. PMID 19914060 DOI: 10.1016/j.sbi.2009.10.016  0.292
2012 Rodriguez-Frías F, Tabernero D, Quer J, Esteban JI, Ortega I, Domingo E, Cubero M, Camós S, Ferrer-Costa C, Sánchez A, Jardí R, Schaper M, Homs M, Garcia-Cehic D, Guardia J, et al. Ultra-deep pyrosequencing detects conserved genomic sites and quantifies linkage of drug-resistant amino acid changes in the hepatitis B virus genome. Plos One. 7: e37874. PMID 22666402 DOI: 10.1371/journal.pone.0037874  0.289
2007 Sierra M, Airaksinen A, González-López C, Agudo R, Arias A, Domingo E. Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe. Journal of Virology. 81: 2012-24. PMID 17151116 DOI: 10.1128/JVI.01606-06  0.288
1999 Ruiz-Jarabo CM, Sevilla N, Dávila M, Gómez-Mariano G, Baranowski E, Domingo E. Antigenic properties and population stability of a foot-and-mouth disease virus with an altered Arg-Gly-Asp receptor-recognition motif. The Journal of General Virology. 1899-1909. PMID 10466785 DOI: 10.1099/0022-1317-80-8-1899  0.283
2022 Hufsky F, Beslic D, Boeckaerts D, Duchene S, González-Tortuero E, Gruber AJ, Guo J, Jansen D, Juma J, Kongkitimanon K, Luque A, Ritsch M, Lencioni Lovate G, Nishimura L, Pas C, ... Domingo E, et al. The International Virus Bioinformatics Meeting 2022. Viruses. 14. PMID 35632715 DOI: 10.3390/v14050973  0.276
2002 Domingo E, Ruiz-Jarabo CM, Sierra S, Arias A, Pariente N, Baranowski E, Escarmis C. Emergence and selection of RNA virus variants: memory and extinction. Virus Research. 82: 39-44. PMID 11885948  0.275
2023 García-Crespo C, Francisco-Recuero I, Gallego I, Camblor-Murube M, Soria ME, López-López A, de Ávila AI, Madejón A, García-Samaniego J, Domingo E, Sánchez-Pacheco A, Perales C. Hepatitis C virus fitness can influence the extent of infection-mediated epigenetic modifications in the host cells. Frontiers in Cellular and Infection Microbiology. 13: 1057082. PMID 36992689 DOI: 10.3389/fcimb.2023.1057082  0.275
2006 Ferrer-Orta C, Arias A, Agudo R, Pérez-Luque R, Escarmís C, Domingo E, Verdaguer N. The structure of a protein primer-polymerase complex in the initiation of genome replication. The Embo Journal. 25: 880-8. PMID 16456546 DOI: 10.1038/sj.emboj.7600971  0.273
2011 Ojosnegros S, García-Arriaza J, Escarmís C, Manrubia SC, Perales C, Arias A, Mateu MG, Domingo E. Viral genome segmentation can result from a trade-off between genetic content and particle stability. Plos Genetics. 7: e1001344. PMID 21437265 DOI: 10.1371/Journal.Pgen.1001344  0.273
2006 Briones C, de Vicente A, Molina-París C, Domingo E. Minority memory genomes can influence the evolution of HIV-1 quasispecies in vivo. Gene. 384: 129-38. PMID 17059869 DOI: 10.1016/j.gene.2006.07.037  0.27
2005 Novella IS, Gilbertson DL, Borrego B, Domingo E, Holland JJ. Adaptability costs in immune escape variants of vesicular stomatitis virus. Virus Research. 107: 27-34. PMID 15567030 DOI: 10.1016/J.Virusres.2004.06.007  0.266
2009 Perales C, Agudo R, Domingo E. Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment. Plos One. 4. PMID 19436746 DOI: 10.1371/Journal.Pone.0005554  0.266
2004 Arnedo-Valero M, Plana M, Mas A, Guilà M, Gil C, Castro P, Garcia F, Domingo E, Gatell JM, Pumarola T. Similar HIV-1 evolution and immunological responses at 10 years despite several therapeutic strategies and host HLA Types. Journal of Medical Virology. 73: 495-501. PMID 15221891 DOI: 10.1002/jmv.20117  0.265
2016 Martín V, Perales C, Fernández-Algar M, Dos Santos HG, Garrido P, Pernas M, Parro V, Moreno M, García-Pérez J, Alcamí J, Torán JL, Abia D, Domingo E, Briones C. An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies. Plos One. 11: e0166902. PMID 27959928 DOI: 10.1371/Journal.Pone.0166902  0.263
2011 Perales C, Martín V, Domingo E. Lethal mutagenesis of viruses. Current Opinion in Virology. 1: 419-422. PMID 22440845 DOI: 10.1016/J.Coviro.2011.09.001  0.259
2012 Perales C, Iranzo J, Manrubia SC, Domingo E. The impact of quasispecies dynamics on the use of therapeutics Trends in Microbiology. 20: 595-603. PMID 22989762 DOI: 10.1016/J.Tim.2012.08.010  0.257
2010 Rodríguez-Calvo T, Ojosnegros S, Sanz-Ramos M, García-Arriaza J, Escarmís C, Domingo E, Sevilla N. New vaccine design based on defective genomes that combines features of attenuated and inactivated vaccines. Plos One. 5: e10414. PMID 20454676 DOI: 10.1371/journal.pone.0010414  0.257
2019 Ariza-Mateos A, Briones C, Perales C, Domingo E, Gómez J. The archaeology of coding RNA. Annals of the New York Academy of Sciences. PMID 31237363 DOI: 10.1111/Nyas.14173  0.255
2004 Arias A, Ruiz-Jarabo CM, Escarmís C, Domingo E. Fitness increase of memory genomes in a viral quasispecies. Journal of Molecular Biology. 339: 405-12. PMID 15136042 DOI: 10.1016/j.jmb.2004.03.061  0.253
2010 Ferrer-Orta C, Sierra M, Agudo R, de la Higuera I, Arias A, Pérez-Luque R, Escarmís C, Domingo E, Verdaguer N. Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin. Journal of Virology. 84: 6188-99. PMID 20392853 DOI: 10.1128/JVI.02420-09  0.246
2016 Domingo E, Schuster P. Quasispecies theory has come of age, and regular updates of the concept of mutation. Introduction. Current Topics in Microbiology and Immunology. 392: ix-xi. PMID 27222902  0.241
2003 Ruiz-Jarabo CM, Miller E, Gómez-Mariano G, Domingo E. Synchronous loss of quasispecies memory in parallel viral lineages: a deterministic feature of viral quasispecies. Journal of Molecular Biology. 333: 553-63. PMID 14556744 DOI: 10.1016/j.jmb.2003.08.054  0.24
2002 Mas A, Vázquez-Alvarez BM, Domingo E, Menéndez-Arias L. Multidrug-resistant HIV-1 reverse transcriptase: involvement of ribonucleotide-dependent phosphorolysis in cross-resistance to nucleoside analogue inhibitors. Journal of Molecular Biology. 323: 181-97. PMID 12381314 DOI: 10.1016/s0022-2836(02)00911-7  0.236
2015 Quer J, Gregori J, Rodríguez-Frias F, Buti M, Madejon A, Perez-del-Pulgar S, Garcia-Cehic D, Casillas R, Blasi M, Homs M, Tabernero D, Alvarez-Tejado M, Muñoz JM, Cubero M, Caballero A, ... ... Domingo E, et al. High-resolution hepatitis C virus subtyping using NS5B deep sequencing and phylogeny, an alternative to current methods. Journal of Clinical Microbiology. 53: 219-26. PMID 25378574 DOI: 10.1128/Jcm.02093-14  0.235
2019 Chen Q, Perales C, Soria ME, García-Cehic D, Gregori J, Rodríguez-Frías F, Buti M, Crespo J, Calleja JL, Tabernero D, Vila M, Lázaro F, Rando A, Nieto-Aponte L, Llorens-Revull M, ... ... Domingo E, et al. Deep-sequencing reveals broad subtype-specific HCV resistance mutations associated with treatment failure. Antiviral Research. 104694. PMID 31857134 DOI: 10.1016/J.Antiviral.2019.104694  0.234
2014 Gregori J, Salicrú M, Domingo E, Sanchez A, Esteban JI, Rodríguez-Frías F, Quer J. Inference with viral quasispecies diversity indices: clonal and NGS approaches. Bioinformatics (Oxford, England). PMID 24389655 DOI: 10.1093/bioinformatics/btt768  0.232
2023 Ariza-Mateos A, Briones C, Perales C, Sobrino F, Domingo E, Gómez J. Archaeological approaches to RNA virus evolution. The Journal of Physiology. PMID 37818797 DOI: 10.1113/JP284416  0.232
2021 Domingo E, Perales C. The time for COVID-19 vaccination. Journal of Virology. PMID 33468542 DOI: 10.1128/JVI.02437-20  0.23
2015 Madejón A, Sheldon J, Francisco-Recuero I, Perales C, Domínguez-Beato M, Lasa M, Sánchez-Perez I, Muntané J, Domingo E, García-Samaniego J, Sánchez-Pacheco A. Hepatitis C virus-mediated Aurora B kinase inhibition modulates inflammatory pathway and viral infectivity. Journal of Hepatology. 63: 312-319. PMID 25733156 DOI: 10.1016/J.Jhep.2015.02.036  0.227
2003 Domingo E. Host-microbe interactions: viruses. Complexities of virus-cell interactions. Current Opinion in Microbiology. 6: 383-5. PMID 12941409 DOI: 10.1016/s1369-5274(03)00094-8  0.219
2010 Martín-Acebes MA, Herrera M, Armas-Portela R, Domingo E, Sobrino F. Cell density-dependent expression of viral antigens during persistence of foot-and-mouth disease virus in cell culture. Virology. 403: 47-55. PMID 20444479 DOI: 10.1016/j.virol.2010.04.005  0.218
2019 Perales C, Gallego I, Ávila AId, Soria ME, Gregori J, Quer J, Domingo E. The increasing impact of lethal mutagenesis of viruses. Future Medicinal Chemistry. 11: 1645-1657. PMID 31469331 DOI: 10.4155/Fmc-2018-0457  0.218
2016 Quer J, Gregori J, Rodríguez-Frias F, Buti M, Madejon A, Perez-Del-Pulgar S, Garcia-Cehic D, Casillas R, Blasi M, Homs M, Tabernero D, Alvarez-Tejado M, Muñoz JM, Cubero M, Caballero A, ... ... Domingo E, et al. Correction for Quer at al., High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods. Journal of Clinical Microbiology. 54: 1933. PMID 27343299 DOI: 10.1128/Jcm.01007-16  0.217
2003 Briones C, Domingo E, Molina-París C. Memory in retroviral quasispecies: experimental evidence and theoretical model for human immunodeficiency virus. Journal of Molecular Biology. 331: 213-29. PMID 12875847 DOI: 10.1016/s0022-2836(03)00661-2  0.214
2003 Manrubia SC, Lázaro E, Pérez-Mercader J, Escarmís C, Domingo E. Fitness distributions in exponentially growing asexual populations. Physical Review Letters. 90: 188102. PMID 12786044 DOI: 10.1103/PhysRevLett.90.188102  0.205
2002 Ruíz-Jarabo CM, Arias A, Molina-París C, Briones C, Baranowski E, Escarmís C, Domingo E. Duration and fitness dependence of quasispecies memory. Journal of Molecular Biology. 315: 285-96. PMID 11786012 DOI: 10.1006/jmbi.2001.5232  0.197
2008 Ojosnegros S, Agudo R, Sierra M, Briones C, Sierra S, González-López C, Domingo E, Cristina J. Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection. Bmc Evolutionary Biology. 8: 207. PMID 18637173 DOI: 10.1186/1471-2148-8-207  0.177
2002 Villén J, Borràs E, Schaaper WM, Meloen RH, Dávila M, Domingo E, Giralt E, Andreu D. Functional mimicry of a discontinuous antigenic site by a designed synthetic peptide. Chembiochem : a European Journal of Chemical Biology. 3: 175-82. PMID 11921395 DOI: 10.1002/1439-7633(20020301)3:2/3<175::Aid-Cbic175>3.0.Co;2-W  0.17
2024 Domingo E, Martínez-González B, García-Crespo C, Somovilla P, de Ávila AI, Soria ME, Durán-Pastor A, Perales C. Reply to Qu et al., "Quasispecies are constantly selected through virus-encoded intracellular reproductive population bottlenecking". Journal of Virology. e0004624. PMID 38445886 DOI: 10.1128/jvi.00046-24  0.168
2015 Perez-Del-Pulgar S, Gregori J, Rodríguez-Frias F, González P, García-Cehic D, Ramírez S, Casillas R, Domingo E, Esteban JI, Forns X, Quer J. Quasispecies dynamics in hepatitis C liver transplant recipients receiving grafts from hepatitis C virus infected donors. The Journal of General Virology. PMID 26395289 DOI: 10.1099/jgv.0.000289  0.154
2002 Woolhouse ME, Webster JP, Domingo E, Charlesworth B, Levin BR. Biological and biomedical implications of the co-evolution of pathogens and their hosts. Nature Genetics. 32: 569-77. PMID 12457190 DOI: 10.1038/Ng1202-569  0.141
2023 Ariza-Mateos A, Briones C, Perales C, Sobrino F, Domingo E, Gómez J. Natural languages and RNA virus evolution. The Journal of Physiology. PMID 37983617 DOI: 10.1113/JP284415  0.138
2024 Conde A, Voces D, Medel-Plaza M, Perales C, de Ávila AI, Aguilera-Correa JJ, de Damborenea JJ, Esteban J, Domingo E, Arenas MA. Fluoride anodic films on stainless-steel fomites to reduce transmission infections. Applied and Environmental Microbiology. e0189223. PMID 38289132 DOI: 10.1128/aem.01892-23  0.131
2005 Tapia N, Fernàndez G, Parera M, Gómez-Mariano G, Clotet B, Quiñones-Mateu M, Domingo E, Martínez MA. Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection. Virology. 338: 1-8. PMID 15939449 DOI: 10.1016/J.Virol.2005.05.008  0.13
2024 García-Crespo C, de Ávila AI, Gallego I, Soria ME, Durán-Pastor A, Somovilla P, Martínez-González B, Muñoz-Flores J, Mínguez P, Salar-Vidal L, Esteban-Muñoz M, Cañar-Camacho E, Ferrer-Orta C, Zuñiga S, Sola I, ... ... Domingo E, et al. Synergism between remdesivir and ribavirin leads to SARS-CoV-2 extinction in cell culture. British Journal of Pharmacology. PMID 38616133 DOI: 10.1111/bph.16344  0.12
2024 Domingo E, Witzany G. Quasispecies productivity. Die Naturwissenschaften. 111: 11. PMID 38372790 DOI: 10.1007/s00114-024-01897-6  0.12
2004 Baranowski E, Ruiz-Jarabo CM, Pariente N, Verdaguer N, Domingo E. Evolution of cell recognition by viruses: a source of biological novelty with medical implications. Advances in Virus Research. 62: 19-111. PMID 14719364 DOI: 10.1016/s0065-3527(03)62002-6  0.118
2010 Bordería AV, Lorenzo-Redondo R, Pernas M, Casado C, Alvaro T, Domingo E, Lopez-Galindez C. Initial fitness recovery of HIV-1 is associated with quasispecies heterogeneity and can occur without modifications in the consensus sequence. Plos One. 5: e10319. PMID 20436678 DOI: 10.1371/journal.pone.0010319  0.111
2015 Domingo E, Schuster P. What Is a Quasispecies? Historical Origins and Current Scope. Current Topics in Microbiology and Immunology. PMID 26318138 DOI: 10.1007/82_2015_453  0.109
2009 Emonet SF, de la Torre JC, Domingo E, Sevilla N. Arenavirus genetic diversity and its biological implications. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 9: 417-29. PMID 19460307 DOI: 10.1016/j.meegid.2009.03.005  0.066
2023 Llorens-Revull M, Martínez-González B, Quer J, Esteban JI, Núñez-Moreno G, Mínguez P, Burgui I, Ramos-Ruíz R, Soria ME, Rico A, Riveiro-Barciela M, Sauleda S, Piron M, Corrales I, Borràs FE, ... ... Domingo E, et al. Comparison of Extracellular Vesicle Isolation Methods for miRNA Sequencing. International Journal of Molecular Sciences. 24. PMID 37569568 DOI: 10.3390/ijms241512183  0.057
2010 Vasbinder JW, Andersson B, Arthur WB, Boasson M, de Boer R, Changeux JP, Domingo E, Eigen M, Fersht A, Frenkel D, Rees M, Groen T, Huber R, Hunt T, Holland J, et al. Transdisciplinary EU science institute needs funds urgently. Nature. 463: 876. PMID 20164899 DOI: 10.1038/463876A  0.048
2009 Domingo E, Wain-Hobson S. The 30th anniversary of quasispecies. Meeting on 'Quasispecies: past, present and future'. Embo Reports. 10: 444-8. PMID 19343047 DOI: 10.1038/embor.2009.61  0.026
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