Clive H. Orchard, BSc, PhD - Publications

Affiliations: 
Physiology University of Bristol, Bristol, England, United Kingdom 

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kong CHT, Bryant SM, Watson JJ, Roth DM, Patel HH, Cannell MB, James AF, Orchard CH. CARDIAC-SPECIFIC OVEREXPRESSION OF CAVEOLIN-3 PRESERVES T-TUBULAR I DURING HEART FAILURE IN MICE. Experimental Physiology. PMID 30786093 DOI: 10.1113/Ep087304  0.462
2018 Bryant SM, Kong CHT, Watson JJ, Gadeberg HC, Roth DM, Patel HH, Cannell MB, James AF, Orchard CH. CAVEOLIN-3 KO DISRUPTS T-TUBULE STRUCTURE AND DECREASES T-TUBULAR I DENSITY IN MOUSE VENTRICULAR MYOCYTES. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30028203 DOI: 10.1152/Ajpheart.00209.2018  0.492
2018 Bryant SM, Kong CHT, Watson JJ, Gadeberg HC, James AF, Cannell MB, Orchard CH. Caveolin-3 dependent loss of t-tubular Iduring hypertrophy and heart failure in mice. Experimental Physiology. PMID 29473235 DOI: 10.1113/Ep086731  0.482
2018 Lewis M, Szobi A, Balaska D, Khaliulin I, Adameova A, Griffiths E, Orchard CH, Suleiman MS. Consecutive Isoproterenol and Adenosine Treatment Confers Marked Protection against Reperfusion Injury in Adult but Not in Immature Heart: A Role for Glycogen. International Journal of Molecular Sciences. 19. PMID 29414860 DOI: 10.3390/Ijms19020494  0.35
2017 Kong CHT, Bryant SM, Watson JJ, Gadeberg HC, Roth DM, Patel HH, Cannell MB, Orchard CH, James AF. The effects of aging on the regulation of t-tubular ICa by caveolin in mouse ventricular myocytes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 29236992 DOI: 10.1093/Gerona/Glx242  0.348
2017 Gadeberg HC, Kong CHT, Bryant SM, James AF, Orchard CH. Cholesterol depletion does not alter the capacitance or Ca handling of the surface or t-tubule membranes in mouse ventricular myocytes. Physiological Reports. 5. PMID 29150591 DOI: 10.14814/Phy2.13500  0.435
2017 Bryant SM, Kong CHT, Cannell MB, Orchard CH, James AF. Loss of caveolin-3-dependent regulation of ICa in rat ventricular myocytes in heart failure. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00458.2017. PMID 29101175 DOI: 10.1152/Ajpheart.00458.2017  0.475
2017 Kong CHT, Rog-Zielinska EA, Orchard CH, Kohl P, Cannell MB. Sub-microscopic analysis of t-tubule geometry in living cardiac ventricular myocytes using a shape-based analysis method. Journal of Molecular and Cellular Cardiology. PMID 28483597 DOI: 10.1016/J.Yjmcc.2017.05.003  0.326
2017 Gadeberg HC, Kong CHT, Bryant SM, James AF, Orchard CH. Sarcolemmal distribution of ICa and INCX and Ca autoregulation in mouse ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00117.2017. PMID 28476922 DOI: 10.1152/Ajpheart.00117.2017  0.524
2017 Kong CH, Rog-Zielinska EA, Orchard CH, Kohl P, Cannell MB. Diffusion in the Transverse-Axial Tubule System of Cardiac Myocytes Biophysical Journal. 112: 122a. DOI: 10.1016/J.Bpj.2016.11.682  0.427
2016 Bond RC, Bryant SM, Watson JJ, Hancox JC, Orchard CH, James AF. Reduced density and altered regulation of rat atrial L-type Ca2+ current in rat heart failure. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00528.2016. PMID 27923791 DOI: 10.1152/ajpheart.00528.2016  0.344
2016 Cheng H, Li J, James AF, Inada S, Choisy SC, Orchard CH, Zhang H, Boyett MR, Hancox JC. Characterization and influence of cardiac background sodium current in the atrioventricular node. Journal of Molecular and Cellular Cardiology. PMID 27132017 DOI: 10.1016/J.Yjmcc.2016.04.014  0.586
2016 James AF, Bond RC, Bryant SM, Watson JJ, Hancox JC, Orchard CH. Down Regulation of L-Type Calcium Current in Rat Atrial Myocytes during Heart Failure Biophysical Journal. 110: 272a. DOI: 10.1016/J.Bpj.2015.11.1477  0.468
2015 Zhang H, Cannell MB, Kim SJ, Watson JJ, Norman R, Calaghan SC, Orchard CH, James AF. Cellular Hypertrophy and Increased Susceptibility to Spontaneous Calcium-Release of Rat Left Atrial Myocytes Due to Elevated Afterload. Plos One. 10: e0144309. PMID 26713852 DOI: 10.1371/Journal.Pone.0144309  0.508
2015 Choisy SC, Cheng H, Orchard CH, James AF, Hancox JC. Electrophysiological properties of myocytes isolated from the mouse atrioventricular node: L-type ICa, IKr, If, and Na-Ca exchange. Physiological Reports. 3. PMID 26607172 DOI: 10.14814/Phy2.12633  0.477
2015 Gadeberg HC, Bryant SM, James AF, Orchard CH. Altered Na/Ca exchange distribution and activity in ventricular myocytes from failing hearts. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00597.2015. PMID 26566728 DOI: 10.1152/Ajpheart.00597.2015  0.535
2015 Bryant SM, Kong CH, Watson J, Cannell MB, James AF, Orchard CH. Altered distribution of ICa impairs Ca release at the t-tubules of ventricular myocytes from failing hearts. Journal of Molecular and Cellular Cardiology. PMID 26103619 DOI: 10.1016/j.yjmcc.2015.06.012  0.462
2015 Avolio E, Rodriguez-Arabaolaza I, Spencer HL, Riu F, Mangialardi G, Slater SC, Rowlinson J, Alvino VV, Idowu OO, Soyombo S, Oikawa A, Swim MM, Kong CH, Cheng H, Jia H, ... ... Orchard CH, et al. Expansion and characterization of neonatal cardiac pericytes provides a novel cellular option for tissue engineering in congenital heart disease. Journal of the American Heart Association. 4: e002043. PMID 26080813 DOI: 10.1161/Jaha.115.002043  0.337
2014 Nisbet AM, Burton FL, Walker NL, Craig MA, Cheng H, Hancox JC, Orchard CH, Smith GL. Acidosis slows electrical conduction through the atrio-ventricular node. Frontiers in Physiology. 5: 233. PMID 25009505 DOI: 10.3389/Fphys.2014.00233  0.348
2014 Pásek M, Simurda J, Orchard CH. Effect of Ca2+ efflux pathway distribution and exogenous Ca2+ buffers on intracellular Ca2+ dynamics in the rat ventricular myocyte: a simulation study. Biomed Research International. 2014: 920208. PMID 24971358 DOI: 10.1155/2014/920208  0.471
2014 Bryant S, Kimura TE, Kong CH, Watson JJ, Chase A, Suleiman MS, James AF, Orchard CH. Stimulation of ICa by basal PKA activity is facilitated by caveolin-3 in cardiac ventricular myocytes. Journal of Molecular and Cellular Cardiology. 68: 47-55. PMID 24412535 DOI: 10.1016/J.Yjmcc.2013.12.026  0.442
2014 Pásek M, Šimurda J, Orchard CH. Effect of Ca2+ efflux pathway distribution and exogenous Ca 2+ buffers on intracellular Ca2+ dynamics in the rat ventricular myocyte: A simulation study Biomed Research International. 2014. DOI: 10.1155/2014/920208  0.366
2013 Orchard CH, Bryant SM, James AF. Do t-tubules play a role in arrhythmogenesis in cardiac ventricular myocytes? The Journal of Physiology. 591: 4141-7. PMID 23652596 DOI: 10.1113/Jphysiol.2013.254540  0.458
2012 Cheng H, Smith GL, Orchard CH, Hancox JC, Burton FL. Inhibition of sarcoplasmic reticulum Ca(2+)-ATPase decreases atrioventricular node-paced heart rate in rabbits. Experimental Physiology. 97: 1131-9. PMID 22562813 DOI: 10.1113/Expphysiol.2012.065110  0.407
2012 Pásek M, Šimurda J, Orchard CH. Role of t-tubules in the control of trans-sarcolemmal ion flux and intracellular Ca 2+ in a model of the rat cardiac ventricular myocyte European Biophysics Journal. 41: 491-503. PMID 22466899 DOI: 10.1007/S00249-012-0804-X  0.4
2011 Du CY, El Harchi A, Zhang YH, Orchard CH, Hancox JC. Pharmacological inhibition of the hERG potassium channel is modulated by extracellular but not intracellular acidosis Journal of Cardiovascular Electrophysiology. 22: 1163-1170. PMID 21489024 DOI: 10.1111/J.1540-8167.2011.02060.X  0.34
2011 Du CY, El Harchi A, McPate MJ, Orchard CH, Hancox JC. Enhanced inhibitory effect of acidosis on hERG potassium channels that incorporate the hERG1b isoform Biochemical and Biophysical Research Communications. 405: 222-227. PMID 21219869 DOI: 10.1016/J.Bbrc.2011.01.014  0.382
2011 Cheng H, Smith GL, Hancox JC, Orchard CH. Inhibition of spontaneous activity of rabbit atrioventricular node cells by KB-R7943 and inhibitors of sarcoplasmic reticulum Ca(2+) ATPase. Cell Calcium. 49: 56-65. PMID 21163524 DOI: 10.1016/J.Ceca.2010.11.008  0.485
2011 Chase A, Orchard CH. Ca efflux via the sarcolemmal Ca ATPase occurs only in the t-tubules of rat ventricular myocytes Journal of Molecular and Cellular Cardiology. 50: 187-193. PMID 20971118 DOI: 10.1016/J.Yjmcc.2010.10.012  0.531
2011 James AF, Zhang H, Kim SJ, Orchard CH. Remodeling of Calcium Handling in Rat Left Atrial Myocytes in a Surgical Model of Elevated Afterload Biophysical Journal. 100: 352a. DOI: 10.1016/J.Bpj.2010.12.2117  0.512
2010 Du CY, Adeniran I, Cheng H, Zhang YH, El Harchi A, McPate MJ, Zhang H, Orchard CH, Hancox JC. Acidosis Impairs the Protective Role of hERG K+ Channels Against Premature Stimulation Journal of Cardiovascular Electrophysiology. 21: 1160-1169. PMID 20455975 DOI: 10.1111/J.1540-8167.2010.01772.X  0.348
2010 Chase A, Colyer J, Orchard CH. Localised Ca channel phosphorylation modulates the distribution of L-type Ca current in cardiac myocytes Journal of Molecular and Cellular Cardiology. 49: 121-131. PMID 20188735 DOI: 10.1016/J.Yjmcc.2010.02.017  0.537
2009 Orchard CH, Pásek M, Brette F. The role of mammalian cardiac t-tubules in excitation-contraction coupling: Experimental and computational approaches Experimental Physiology. 94: 509-519. PMID 19297389 DOI: 10.1113/Expphysiol.2008.043984  0.384
2009 Cheng H, Smith GL, Orchard CH, Hancox JC. Acidosis inhibits spontaneous activity and membrane currents in myocytes isolated from the rabbit atrioventricular node Journal of Molecular and Cellular Cardiology. 46: 75-85. PMID 18950636 DOI: 10.1016/J.Yjmcc.2008.09.709  0.422
2008 Ridley JM, Cheng H, Harrison OJ, Jones SK, Smith GL, Hancox JC, Orchard CH. Spontaneous frequency of rabbit atrioventricular node myocytes depends on SR function. Cell Calcium. 44: 580-91. PMID 18550162 DOI: 10.1016/J.Ceca.2008.04.004  0.485
2008 Pásek M, Šimurda J, Orchard CH, Christé G. A model of the guinea-pig ventricular cardiac myocyte incorporating a transverse-axial tubular system Progress in Biophysics and Molecular Biology. 96: 258-280. PMID 17888503 DOI: 10.1016/J.Pbiomolbio.2007.07.022  0.464
2008 Pásek M, Brette F, Nelson A, Pearce C, Qaiser A, Christe G, Orchard CH. Quantification of t-tubule area and protein distribution in rat cardiac ventricular myocytes. Progress in Biophysics and Molecular Biology. 96: 244-57. PMID 17881039 DOI: 10.1016/J.Pbiomolbio.2007.07.016  0.384
2008 Pásek M, Šimurda J, Christé G, Orchard CH. Modelling the cardiac transverse-axial tubular system Progress in Biophysics and Molecular Biology. 96: 226-243. PMID 17868782 DOI: 10.1016/J.Pbiomolbio.2007.07.021  0.354
2007 Orchard C, Brette F. t-Tubules and sarcoplasmic reticulum function in cardiac ventricular myocytes. Cardiovascular Research. 77: 237-44. PMID 18006490 DOI: 10.1093/Cvr/Cvm002  0.533
2007 Brette F, Orchard C. Resurgence of cardiac t-tubule research. Physiology (Bethesda, Md.). 22: 167-73. PMID 17557937 DOI: 10.1152/Physiol.00005.2007  0.464
2007 Fowler MR, Naz JR, Graham MD, Orchard CH, Harrison SM. Age and hypertrophy alter the contribution of sarcoplasmic reticulum and Na+/Ca2+ exchange to Ca2+ removal in rat left ventricular myocytes. Journal of Molecular and Cellular Cardiology. 42: 582-9. PMID 17234206 DOI: 10.1016/J.Yjmcc.2006.12.003  0.494
2007 Leach RN, Brette F, Orchard CH. Antisense oligonucleotide against the Ca channel β subunit decreases L-type Ca current in rat ventricular myocytes Biochemical and Biophysical Research Communications. 352: 794-798. PMID 17141184 DOI: 10.1016/J.Bbrc.2006.11.099  0.475
2007 Fowler MR, Orchard CH, Harrison SM. Cellular distribution of calcium current is unaltered during compensated hypertrophy in the spontaneously hypertensive rat. PflüGers Archiv : European Journal of Physiology. 453: 463-9. PMID 17066274 DOI: 10.1007/S00424-006-0147-5  0.529
2006 Orchard C. Downhill all the way: H(+) gradients within cardiac myocytes. Biophysical Journal. 92: 371-2. PMID 17056722 DOI: 10.1529/Biophysj.106.097576  0.363
2006 Brette F, Orchard CH. Density and sub-cellular distribution of cardiac and neuronal sodium channel isoforms in rat ventricular myocytes Biochemical and Biophysical Research Communications. 348: 1163-1166. PMID 16904633 DOI: 10.1016/J.Bbrc.2006.07.189  0.434
2006 Orchard C. T-tubule trouble. The Journal of Physiology. 574: 330. PMID 16728445 DOI: 10.1113/Jphysiol.2006.113803  0.529
2006 Brette F, Orchard CH. No apparent requirement for neuronal sodium channels in excitation-contraction coupling in rat ventricular myocytes Circulation Research. 98: 667-674. PMID 16484618 DOI: 10.1161/01.Res.0000209963.02720.70  0.493
2006 Brette F, Sallé L, Orchard CH. Quantification of calcium entry at the T-tubules and surface membrane in rat ventricular myocytes Biophysical Journal. 90: 381-389. PMID 16214862 DOI: 10.1529/Biophysj.105.069013  0.563
2005 Brette F, Despa S, Bers DM, Orchard CH. Spatiotemporal characteristics of SR Ca2+ uptake and release in detubulated rat ventricular myocytes Journal of Molecular and Cellular Cardiology. 39: 804-812. PMID 16198369 DOI: 10.1016/J.Yjmcc.2005.08.005  0.466
2005 Leach RN, Desai JC, Orchard CH. Effect of cytoskeleton disruptors on L-type Ca channel distribution in rat ventricular myocytes Cell Calcium. 38: 515-526. PMID 16137761 DOI: 10.1016/J.Ceca.2005.07.006  0.519
2005 Fowler MR, Naz JR, Graham MD, Bru-Mercier G, Harrison SM, Orchard CH. Decreased Ca2+ extrusion via Na+/Ca2+ exchange in epicardial left ventricular myocytes during compensated hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2431-8. PMID 15615841 DOI: 10.1152/Ajpheart.01069.2004  0.447
2004 Brette F, Sallé L, Orchard CH. Differential modulation of L-type Ca2+ current by SR Ca2+ release at the T-tubules and surface membrane of rat ventricular myocytes. Circulation Research. 95: e1-7. PMID 15192026  0.425
2004 Fowler MR, Dobson RS, Orchard CH, Harrison SM. Functional consequences of detubulation of isolated rat ventricular myocytes. Cardiovascular Research. 62: 529-37. PMID 15158145 DOI: 10.1016/J.Cardiores.2004.02.008  0.456
2004 Brette F, Rodriguez P, Komukai K, Colyer J, Orchard CH. β-adrenergic stimulation restores the Ca transient of ventricular myocytes lacking t-tubules Journal of Molecular and Cellular Cardiology. 36: 265-275. PMID 14871554 DOI: 10.1016/j.yjmcc.2003.11.002  0.364
2003 Despa S, Brette F, Orchard CH, Bers DM. Na/Ca Exchange and Na/K-ATPase Function Are Equally Concentrated in Transverse Tubules of Rat Ventricular Myocytes Biophysical Journal. 85: 3388-3396. PMID 14581240 DOI: 10.1016/S0006-3495(03)74758-4  0.315
2003 Brette F, Orchard C. T-tubule function in mammalian cardiac myocytes. Circulation Research. 92: 1182-92. PMID 12805236 DOI: 10.1161/01.RES.0000074908.17214.FD  0.383
2003 Zhang H, Noble D, Cannell M, Orchard CH, Lancaster M, Jones SA, Boyett MR, Holden AV, Jafri MS, Sobie EA, Lederer WJ, Demir SS, Michailova A, Delprincipe F, Egger M, et al. Dynamics of cardiac intracellular Ca2+ handling - From experiments to virtual cells International Journal of Bifurcation and Chaos in Applied Sciences and Engineering. 13: 3535-3560. DOI: 10.1142/S0218127403008843  0.325
2002 Yang Z, Pascarel C, Steele DS, Komukai K, Brette F, Orchard CH. Na+-Ca2+ exchange activity is localized in the T-tubules of rat ventricular myocytes. Circulation Research. 91: 315-22. PMID 12193464 DOI: 10.1161/01.Res.0000030180.06028.23  0.449
2002 Komukai K, Pascarel C, Brette F, Orchard CH, Mochizuki S. S4-4 Camkii modulates intracellular Ca regulation and ICa in rat ventricular myocytes during acidosis Journal of Molecular and Cellular Cardiology. 34: A11. DOI: 10.1016/S0022-2828(02)90276-2  0.353
2000 Choi HS, Trafford AW, Orchard CH, Eisner DA. The effect of acidosis on systolic Ca2+ and sarcoplasmic reticulum calcium content in isolated rat ventricular myocytes. The Journal of Physiology. 529: 661-8. PMID 11118496 DOI: 10.1111/J.1469-7793.2000.00661.X  0.416
2000 Kawai M, Lee JA, Orchard CH. Effects of the Ca2+ sensitizer EMD 57033 on intracellular Ca2+ in rat ventricular myocytes: Relevance to arrhythmogenesis during positive inotropy Clinical Science. 99: 547-554. PMID 11099399 DOI: 10.1042/Cs20000063  0.393
1998 Hulme JT, Orchard CH. Effect of acidosis on Ca2+ uptake and release by sarcoplasmic reticulum of intact rat ventricular myocytes American Journal of Physiology - Heart and Circulatory Physiology. 275: H977-H987. PMID 9724303  0.352
1998 Kawai M, Hussain M, Orchard CH. Cs+ inhibits spontaneous Ca2+ release from sarcoplasmic reticulum of skinned cardiac myocytes American Journal of Physiology - Heart and Circulatory Physiology. 275: H422-H430. PMID 9683429  0.337
1998 Orchard CH, Smith GL, Steele DS. Effects of cytosolic Ca2+ on the Ca2+ content of the sarcoplasmic reticulum in saponin-permeabilized rat ventricular trabeculae. PflüGers Archiv : European Journal of Physiology. 435: 555-63. PMID 9446704 DOI: 10.1007/S004240050552  0.377
1997 Hussain M, Orchard CH. Sarcoplasmic reticulum Ca2+ content, L-type Ca2+ current and the Ca2+ transient in rat myocytes during beta-adrenergic stimulation. The Journal of Physiology. 505: Pt 2/-. PMID 9423181  0.362
1997 Hussain M, Drago GA, Colyer J, Orchard CH. Rate-dependent abbreviation of Ca2+ transient in rat heart is independent of phospholamban phosphorylation. The American Journal of Physiology. 273: H695-706. PMID 9277486  0.349
1997 Hussain M, Orchard CH. Sarcoplasmic reticulum Ca2+ content, L-type Ca2+ current and the Ca2+ transient in rat myocytes during β-adrenergic stimulation Journal of Physiology. 505: 385-402. DOI: 10.1111/j.1469-7793.1997.385bb.x  0.372
1997 Hussain M, Drago GA, Colyer J, Orchard CH. Rate-dependent abbreviation of Ca2+ transient in rat heart is independent of phospholamban phosphorylation American Journal of Physiology - Heart and Circulatory Physiology. 42: H695-H706.  0.349
1996 Hongo K, White E, Le Guennec JY, Orchard CH. Changes in [Ca2+]i, [Na+]i and Ca2+ current in isolated rat ventricular myocytes following an increase in cell length Journal of Physiology. 491: 609-619. PMID 8815197  0.421
1995 White E, Boyett MR, Orchard CH. The effects of mechanical loading and changes of length on single guinea-pig ventricular myocytes Journal of Physiology. 482: 93-107. PMID 7730993  0.324
1995 Hongo K, White E, Orchard CH. Effect of stretch on contraction and the Ca2+ transient in ferret ventricular muscles during hypoxia and acidosis American Journal of Physiology - Cell Physiology. 269: C690-C697. PMID 7573399  0.303
1995 Orchard CH, Mustafa MR, White E. Oscillations and waves of intracellular [Ca2+] in cardiac muscle cells Chaos, Solitons and Fractals. 5: 447-453,455-458. DOI: 10.1016/0960-0779(93)E0036-B  0.314
1993 White J, Lee JA, Shah N, Orchard CH. Differential effects of the optical isomers of EMD 53998 on contraction and cytoplasmic Ca2+ in isolated ferret cardiac muscle Circulation Research. 73: 61-70. PMID 8508534  0.304
1992 Harrison SM, Frampton JE, McCall E, Boyett MR, Orchard CH. Contraction and intracellular Ca2+, Na+, and H+ during acidosis in rat ventricular myocytes American Journal of Physiology - Cell Physiology. 262: C348-C357. PMID 1539627 DOI: 10.1152/Ajpcell.1992.262.2.C348  0.41
1992 Frampton JE, Orchard CH. The effect of a calmodulin inhibitor on intracellular [Ca2+] and contraction in isolated rat ventricular myocytes Journal of Physiology. 453: 385-400. PMID 1464834  0.369
1992 ORCHARD C. The effect of bathing 6Ca2+9 on caffeine-induced Ca2+ release from the sarcoplasmic reticulum of saponin treated rat ventricular trabeculae Journal of Molecular and Cellular Cardiology. 24: 45. DOI: 10.1016/0022-2828(92)93455-S  0.364
1992 Frampton JE, Orchard CH. The effect of the calmodulin inhibitor W7 upon intracellular [Ca2+] (Ca(i)) and contraction in ventricular myocytes isolated from rat hearts Journal of Physiology. 446: 335P.  0.414
1992 Orchard CH. The effect of varying pH on intracellular Ca2+ and force in papillary muscles isolated from ferret hearts Journal of Physiology. 446: 336P.  0.312
1991 Orchard CH, Hamilton DL, Astles P, McCall E, Jewell BR. The effect of acidosis on the relationship between Ca2+ and force in isolated ferret cardiac muscle Journal of Physiology. 436: 559-578. PMID 2061846 DOI: 10.1113/jphysiol.1991.sp018567  0.332
1991 Orchard CH, McCall E, Kirby MS, Boyett MR. Mechanical alternans during acidosis in ferret heart muscle Circulation Research. 68: 69-76. PMID 1984873  0.346
1991 Frampton JE, Harrison SM, Boyett MR, Orchard CH. Ca2+ and Na+ in rat myocytes showing different force-frequency relationships American Journal of Physiology - Cell Physiology. 261: C739-C750. PMID 1951665 DOI: 10.1152/Ajpcell.1991.261.5.C739  0.327
1991 Frampton JE, Orchard CH, Boyett MR. Diastolic, systolic and sarcoplasmic reticulum [Ca2+] during inotropic interventions in isolated rat myocytes Journal of Physiology. 437: 351-375. PMID 1890639  0.377
1991 Frampton JE, Harrison SM, Orchard CH. [Ca2+] and [Na+] in rat ventricular myocytes showing negative and positive force frequency relationships Advances in Experimental Medicine and Biology. 311: 335-336. PMID 1529764 DOI: 10.1007/978-1-4615-3362-7_29  0.314
1990 Frampton JE, Orchard CH, Boyett MR. The relationship between diastolic and systolic intracellular [Ca2+] ([Ca2+](i)) in ventricular myocytes isolated from rat hearts Journal of Physiology. 425: 53P.  0.412
1988 Boyett MR, Kirby MS, Orchard CH, Roberts A. The negative inotropic effect of acetylcholine on ferret ventricular myocardium Journal of Physiology. 404: 613-635. PMID 3253444  0.386
1988 McIvor ME, Orchard CH, Lakatta EG. Dissociation of changes in apparent myofibrillar Ca2+ sensitivity and twitch relaxation induced by adrenergic and cholinergic stimulation in isolated ferret cardiac muscle Journal of General Physiology. 92: 509-529. PMID 3204364  0.322
1988 Boyett MR, Kirby MS, Orchard CH. Rapid regulation of the 'second inward current' by intracellular calcium in isolated rat and ferret ventricular myocytes Journal of Physiology. 407: 77-102. PMID 2855743  0.418
1987 Orchard CH, Houser SR, Kort AA, Bahinski A, Capogrossi MC, Lakatta EG. Acidosis facilitates spontaneous sarcoplasmic reticulum Ca2+ release in rat myocardium. The Journal of General Physiology. 90: 145-65. PMID 3625165 DOI: 10.1085/Jgp.90.1.145  0.348
1985 Orchard CH, Allen DG, Morris PG. The role of intracellular [Ca2+] and [H+] in contractile failure of the hypoxic heart. Advances in Myocardiology. 6: 417-27. PMID 3992041  0.338
1985 Sánchez de León R, Orchard CH, Chakrabarti MK, Sykes K, Brajkovich I. Effect of plasma colloid osmotic pressure on fluid filtration rate in isolated rabbit lungs. Critical Care Medicine. 13: 668-71. PMID 2410187  0.46
1984 Allen DG, Eisner DA, Orchard CH. Characterization of oscillations of intracellular calcium concentration in ferret ventricular muscle. The Journal of Physiology. 352: 113-28. PMID 6747885 DOI: 10.1113/Jphysiol.1984.Sp015281  0.33
1984 Allen DG, Eisner DA, Orchard CH. Factors influencing free intracellular calcium concentration in quiescent ferret ventricular muscle. The Journal of Physiology. 350: 615-30. PMID 6747860 DOI: 10.1113/Jphysiol.1984.Sp015221  0.37
1984 Eisner DA, Orchard CH, Allen DG. Control of intracellular ionized calcium concentration by sarcolemmal and intracellular mechanisms. Journal of Molecular and Cellular Cardiology. 16: 137-46. PMID 6716490 DOI: 10.1016/S0022-2828(84)80702-6  0.38
1983 Orchard CH, Eisner DA, Allen DG. Oscillations of intracellular Ca2+ in mammalian cardiac muscle. Nature. 304: 735-8. PMID 6888540 DOI: 10.1038/304735A0  0.428
1983 Allen DG, Eisner DA, Lab MJ, Orchard CH. The effects of low sodium solutions on intracellular calcium concentration and tension in ferret ventricular muscle. The Journal of Physiology. 345: 391-407. PMID 6663506 DOI: 10.1113/Jphysiol.1983.Sp014984  0.351
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