Year |
Citation |
Score |
2021 |
Elhalem E, Bellomo A, Cooke M, Scravaglieri A, Pearce LV, Peach ML, Gandolfi Donadío L, Kazanietz MG, Comin MJ. Design, Synthesis, and Characterization of Novel -1 Heterocyclic DAG-Lactones as PKC Activators. Journal of Medicinal Chemistry. PMID 34279947 DOI: 10.1021/acs.jmedchem.1c00739 |
0.77 |
|
2017 |
Elhalem E, Donadío LG, Zhou X, Lewin NE, Garcia LC, Lai CC, Kelley JA, Peach ML, Blumberg PM, Comin MJ. Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP. Bioorganic & Medicinal Chemistry. PMID 28392275 DOI: 10.1016/J.Bmc.2017.03.022 |
0.76 |
|
2017 |
Elhalem E, Donadío LG, Zhou X, Lewin NE, Garcia LC, Lai CC, Kelley JA, Peach ML, Blumberg PM, Comin MJ. Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP. Bioorganic & Medicinal Chemistry. PMID 28392275 DOI: 10.1016/J.Bmc.2017.03.022 |
0.76 |
|
2014 |
Garcia LC, Donadío LG, Mann E, Kolusheva S, Kedei N, Lewin NE, Hill CS, Kelsey JS, Yang J, Esch TE, Santos M, Peach ML, Kelley JA, Blumberg PM, Jelinek R, ... ... Comin MJ, et al. Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP. Bioorganic & Medicinal Chemistry. 22: 3123-40. PMID 24794745 DOI: 10.1016/J.Bmc.2014.04.024 |
0.587 |
|
2014 |
Garcia LC, Donadío LG, Mann E, Kolusheva S, Kedei N, Lewin NE, Hill CS, Kelsey JS, Yang J, Esch TE, Santos M, Peach ML, Kelley JA, Blumberg PM, Jelinek R, ... ... Comin MJ, et al. Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP. Bioorganic & Medicinal Chemistry. 22: 3123-40. PMID 24794745 DOI: 10.1016/J.Bmc.2014.04.024 |
0.587 |
|
2010 |
Raifman O, Kolusheva S, Comin MJ, Kedei N, Lewin NE, Blumberg PM, Marquez VE, Jelinek R. Membrane anchoring of diacylglycerol lactones substituted with rigid hydrophobic acyl domains correlates with biological activities. The Febs Journal. 277: 233-43. PMID 19961537 DOI: 10.1111/J.1742-4658.2009.07477.X |
0.526 |
|
2010 |
Comin MJ, Pujol CA, Damonte EB, Rodriguez JB. ChemInform Abstract: Synthesis of C-5′-nor-Dideoxycarbanucleosides Structurally Related to Neplanocin C. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200010208 |
0.556 |
|
2009 |
Comin MJ, Czifra G, Kedei N, Telek A, Lewin NE, Kolusheva S, Velasquez JF, Kobylarz R, Jelinek R, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths. Journal of Medicinal Chemistry. 52: 3274-83. PMID 19379015 DOI: 10.1021/Jm900186M |
0.523 |
|
2009 |
Comin MJ, Czifra G, Kedei N, Telek A, Lewin NE, Kolusheva S, Velasquez JF, Kobylarz R, Jelinek R, Blumberg PM, Marquez VE. Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths. Journal of Medicinal Chemistry. 52: 3274-83. PMID 19379015 DOI: 10.1021/Jm900186M |
0.523 |
|
2008 |
Philosof-Mazor L, Volinsky R, Comin MJ, Lewin NE, Kedei N, Blumberg PM, Marquez VE, Jelinek R. Self-assembly and lipid interactions of diacylglycerol lactone derivatives studied at the air/water interface. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 11043-52. PMID 18788772 DOI: 10.1021/La802204N |
0.481 |
|
2008 |
Philosof-Mazor L, Volinsky R, Comin MJ, Lewin NE, Kedei N, Blumberg PM, Marquez VE, Jelinek R. Self-assembly and lipid interactions of diacylglycerol lactone derivatives studied at the air/water interface. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 11043-52. PMID 18788772 DOI: 10.1021/La802204N |
0.481 |
|
2008 |
Comin MJ, Vu BC, Boyer PL, Liao C, Hughes SH, Marquez VE. D-(+)-iso-methanocarbathymidine: a high-affinity substrate for herpes simplex virus 1 thymidine kinase. Chemmedchem. 3: 1129-34. PMID 18399509 DOI: 10.1002/cmdc.200800027 |
0.511 |
|
2008 |
Comin MJ, Vu BC, Boyer PL, Liao C, Hughes SH, Marquez VE. D-(+)-iso-methanocarbathymidine: a high-affinity substrate for herpes simplex virus 1 thymidine kinase. Chemmedchem. 3: 1129-34. PMID 18399509 DOI: 10.1002/cmdc.200800027 |
0.511 |
|
2007 |
Marquez VE, Comin MJ. Rearranging the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve binding recognition by kinases. Nucleosides, Nucleotides & Nucleic Acids. 26: 585-8. PMID 18066860 DOI: 10.1080/15257770701490175 |
0.304 |
|
2007 |
Marquez VE, Comin MJ. Rearranging the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve binding recognition by kinases. Nucleosides, Nucleotides & Nucleic Acids. 26: 585-8. PMID 18066860 DOI: 10.1080/15257770701490175 |
0.567 |
|
2007 |
Comin MJ, Agbaria R, Ben-Kasus T, Huleihel M, Liao C, Sun G, Nicklaus MC, Deschamps JR, Parrish DA, Marquez VE. Sculpting the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve recognition by herpes thymidine kinase. Journal of the American Chemical Society. 129: 6216-22. PMID 17451242 DOI: 10.1021/ja0688732 |
0.567 |
|
2007 |
Comin MJ, Agbaria R, Ben-Kasus T, Huleihel M, Liao C, Sun G, Nicklaus MC, Deschamps JR, Parrish DA, Marquez VE. Sculpting the bicyclo[3.1.0]hexane template of carbocyclic nucleosides to improve recognition by herpes thymidine kinase. Journal of the American Chemical Society. 129: 6216-22. PMID 17451242 DOI: 10.1021/ja0688732 |
0.567 |
|
2006 |
Comin MJ, Parrish DA, Deschamps JR, Marquez VE. Synthesis of bicyclo[3.1.0]hexanes functionalized at the tip of the cyclopropane ring. Application to the synthesis of carbocyclic nucleosides. Organic Letters. 8: 705-8. PMID 16468747 DOI: 10.1021/ol052886n |
0.563 |
|
2006 |
Comin MJ, Parrish DA, Deschamps JR, Marquez VE. Synthesis of bicyclo[3.1.0]hexanes functionalized at the tip of the cyclopropane ring. Application to the synthesis of carbocyclic nucleosides. Organic Letters. 8: 705-8. PMID 16468747 DOI: 10.1021/ol052886n |
0.563 |
|
2006 |
Elhalem E, Comin MJ, Rodriguez JB. Synthesis of Conformationally Locked Carbocyclic Nucleosides Built on a Thiabicyclo[3.1.0]hexane System as a Pseudosugar Surrogate European Journal of Organic Chemistry. 2006: 4473-4482. DOI: 10.1002/EJOC.200600488 |
0.744 |
|
2005 |
Marquez VE, Choi Y, Comin MJ, Russ P, George C, Huleihel M, Ben-Kasus T, Agbaria R. Understanding how the herpes thymidine kinase orchestrates optimal sugar and nucleobase conformations to accommodate its substrate at the active site: a chemical approach. Journal of the American Chemical Society. 127: 15145-50. PMID 16248655 DOI: 10.1021/Ja053789S |
0.543 |
|
2005 |
Elhalem E, Comin MJ, Leitofuter J, García-Liñares G, Rodriguez JB. Synthetic studies toward the preparation of (4R,5R)-(−)-3-[(benzyloxy)methyl]-4,5-O-isopropylidene-cyclopenten-2-one: an important synthetic intermediate for carbanucleosides Tetrahedron: Asymmetry. 16: 425-431. DOI: 10.1016/J.TETASY.2004.11.069 |
0.704 |
|
2004 |
Gao ZG, Jeong LS, Moon HR, Kim HO, Choi WJ, Shin DH, Elhalem E, Comin MJ, Melman N, Mamedova L, Gross AS, Rodriguez JB, Jacobson KA. Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety. Biochemical Pharmacology. 67: 893-901. PMID 15104242 DOI: 10.1016/J.Bcp.2003.10.006 |
0.716 |
|
2004 |
Comin MJ, Elhalem E, Rodriguez JB. Cerium ammonium nitrate: a new catalyst for regioselective protection of glycols Tetrahedron. 60: 11851-11860. DOI: 10.1016/J.TET.2004.09.097 |
0.705 |
|
2003 |
Choi Y, George C, Comin MJ, Barchi JJ, Kim HS, Jacobson KA, Balzarini J, Mitsuya H, Boyer PL, Hughes SH, Marquez VE. A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude. Journal of Medicinal Chemistry. 46: 3292-9. PMID 12852759 DOI: 10.1021/Jm030116G |
0.475 |
|
2003 |
Choi Y, George C, Comin MJ, Barchi JJ, Kim HS, Jacobson KA, Balzarini J, Mitsuya H, Boyer PL, Hughes SH, Marquez VE. A conformationally locked analogue of the anti-HIV agent stavudine. An important correlation between pseudorotation and maximum amplitude. Journal of Medicinal Chemistry. 46: 3292-9. PMID 12852759 DOI: 10.1021/Jm030116G |
0.475 |
|
2003 |
Rodríguez JB, Comin MJ. New progresses in the enantioselective synthesis and biological properties of carbocyclic nucleosides. Mini Reviews in Medicinal Chemistry. 3: 95-114. PMID 12570843 DOI: 10.2174/1389557033405331 |
0.599 |
|
2003 |
Rodríguez JB, Comin MJ. New progresses in the enantioselective synthesis and biological properties of carbocyclic nucleosides. Mini Reviews in Medicinal Chemistry. 3: 95-114. PMID 12570843 DOI: 10.2174/1389557033405331 |
0.599 |
|
2003 |
Comin MJ, Rodriguez JB, Russ P, Marquez VE. Synthesis of conformationally locked carbocyclic nucleosides built on an oxabicyclo[3.1.0]hexane system Tetrahedron. 59: 295-301. DOI: 10.1016/S0040-4020(02)01528-4 |
0.603 |
|
2003 |
Rodriguez JB, Comin MJ. New Progresses in the Enantioselective Synthesis and Biological Properties of Carbocyclic Nucleosides Cheminform. 34. DOI: 10.1002/CHIN.200336234 |
0.586 |
|
2002 |
Comin MJ, Leitofuter J, Rodrı́guez JB. Enantioselective synthesis of (+)-neplanocin F Tetrahedron. 58: 3129-3136. DOI: 10.1016/S0040-4020(02)00287-9 |
0.518 |
|
2000 |
Comin MJ, Rodriguez JB. ChemInform Abstract: First Synthesis of (-)-Neplanocin C. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200042214 |
0.57 |
|
1999 |
Comin MJ, Pujol CA, Damonte EB, Rodriguez JB. Synthesis of C-5'-nor-dideoxycarbanucleosides structurally related to neplanocin C. Nucleosides & Nucleotides. 18: 2219-31. PMID 10616727 DOI: 10.1080/07328319908044877 |
0.333 |
|
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