| Year |
Citation |
Score |
| 2021 |
Hinman JD, Ngo KJ, Kim D, Chen C, Abraham CR, Ghanbari M, Ikram MA, Kushner SA, Kawaguchi R, Coppola G, Goth K, Bellusci S, Hernandez I, Kosik KS, Fogel BL. miR-142-3p Regulates Cortical Oligodendrocyte Gene Co-expression Networks Associated with Tauopathy. Human Molecular Genetics. PMID 33555315 DOI: 10.1093/hmg/ddaa252 |
0.696 |
|
| 2020 |
Wolf EJ, Chen CD, Zhao X, Zhou Z, Morrison FG, Daskalakis NP, Stone A, Schichman S, Grenier JG, Fein-Schaffer D, Huber BR, Abraham CR, Miller MW, Logue MW. Klotho, PTSD, and advanced epigenetic age in cortical tissue. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33096543 DOI: 10.1038/s41386-020-00884-5 |
0.535 |
|
| 2020 |
Chen CD, Rudy MA, Zeldich E, Abraham CR. A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32347987 DOI: 10.1096/Fj.202000171R |
0.794 |
|
| 2020 |
Chen CD, Li Y, Chen AK, Rudy MA, Nasse JS, Zeldich E, Polanco TJ, Abraham CR. Identification of the cleavage sites leading to the shed forms of human and mouse anti-aging and cognition-enhancing protein Klotho. Plos One. 15: e0226382. PMID 31929539 DOI: 10.1371/Journal.Pone.0226382 |
0.792 |
|
| 2019 |
Delitsikou V, Jarad G, Rajaram RD, Ino F, Rutkowski JM, Chen CD, Santos CXC, Scherer PE, Abraham CR, Shah AM, Feraille E, Miner JH, de Seigneux S. Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31907991 DOI: 10.1096/Fj.201900893R |
0.569 |
|
| 2019 |
Zeldich E, Chen CD, Boden E, Howat B, Nasse JS, Zeldich D, Lambert AG, Yuste A, Cherry JD, Mathias RM, Ma Q, Lau NC, McKee AC, Hatzipetros T, Abraham CR. Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1) Mouse Model of ALS. Journal of Molecular Neuroscience : Mn. PMID 31250273 DOI: 10.1007/S12031-019-01356-2 |
0.772 |
|
| 2019 |
Chen CD, Zeldich E, Khodr C, Camara K, Tung TY, Lauder EC, Mullen P, Polanco TJ, Liu YY, Zeldich D, Xia W, Van Nostrand WE, Brown LE, Porco JA, Abraham CR. Small Molecule Amyloid-β Protein Precursor Processing Modulators Lower Amyloid-β Peptide Levels via cKit Signaling. Journal of Alzheimer's Disease : Jad. 67: 1089-1106. PMID 30776010 DOI: 10.3233/Jad-180923 |
0.777 |
|
| 2018 |
Chen CD, Zeldich E, Li Y, Yuste A, Abraham CR. Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex. Journal of Molecular Neuroscience : Mn. PMID 29352444 DOI: 10.1007/S12031-017-1011-0 |
0.787 |
|
| 2015 |
Zeldich E, Chen CD, Avila R, Medicetty S, Abraham CR. The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination. Journal of Molecular Neuroscience : Mn. PMID 26067431 DOI: 10.1007/S12031-015-0598-2 |
0.771 |
|
| 2015 |
Chen CD, Li H, Liang J, Hixson K, Zeldich E, Abraham CR. The anti-aging and tumor suppressor protein Klotho enhances differentiation of a human oligodendrocytic hybrid cell line. Journal of Molecular Neuroscience : Mn. 55: 76-90. PMID 24907942 DOI: 10.1007/S12031-014-0336-1 |
0.791 |
|
| 2014 |
Chen CD, Tung TY, Liang J, Zeldich E, Tucker Zhou TB, Turk BE, Abraham CR. Identification of cleavage sites leading to the shed form of the anti-aging protein klotho. Biochemistry. 53: 5579-87. PMID 25110992 DOI: 10.1021/Bi500409N |
0.758 |
|
| 2014 |
Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, et al. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Annals of Neurology. 76: 379-92. PMID 25043464 DOI: 10.1002/Ana.24219 |
0.762 |
|
| 2014 |
Zeldich E, Chen CD, Colvin TA, Bove-Fenderson EA, Liang J, Tucker Zhou TB, Harris DA, Abraham CR. The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. The Journal of Biological Chemistry. 289: 24700-15. PMID 25037225 DOI: 10.1074/Jbc.M114.567321 |
0.744 |
|
| 2013 |
Tucker Zhou TB, King GD, Chen C, Abraham CR. Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk. The Journal of Biological Chemistry. 288: 36302-11. PMID 24217253 DOI: 10.1074/Jbc.M113.490052 |
0.76 |
|
| 2013 |
So PP, Khodr CE, Chen CD, Abraham CR. Comparable dimerization found in wildtype and familial Alzheimer's disease amyloid precursor protein mutants. American Journal of Neurodegenerative Disease. 2: 15-28. PMID 23515184 |
0.785 |
|
| 2013 |
Chen CD, Sloane JA, Li H, Aytan N, Giannaris EL, Zeldich E, Hinman JD, Dedeoglu A, Rosene DL, Bansal R, Luebke JI, Kuro-o M, Abraham CR. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1927-39. PMID 23365232 DOI: 10.1523/Jneurosci.2080-12.2013 |
0.78 |
|
| 2013 |
Zeldich E, Chen C, Abraham C. P3-068: Klotho gene protects primary hippocampal neurons from oxidative stress Alzheimer's & Dementia. 9: P575-P575. DOI: 10.1016/J.Jalz.2013.05.1138 |
0.497 |
|
| 2012 |
Abraham CR, Chen C, Cuny GD, Glicksman MA, Zeldich E. Small-molecule Klotho enhancers as novel treatment of neurodegeneration. Future Medicinal Chemistry. 4: 1671-9. PMID 22924505 DOI: 10.4155/Fmc.12.134 |
0.788 |
|
| 2012 |
So PP, Zeldich E, Seyb KI, Huang MM, Concannon JB, King GD, Chen CD, Cuny GD, Glicksman MA, Abraham CR. Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerization. American Journal of Neurodegenerative Disease. 1: 75-87. PMID 22822474 |
0.785 |
|
| 2012 |
King GD, Chen C, Huang MM, Zeldich E, Brazee PL, Schuman ER, Robin M, Cuny GD, Glicksman MA, Abraham CR. Identification of novel small molecules that elevate Klotho expression. The Biochemical Journal. 441: 453-61. PMID 21939436 DOI: 10.1042/Bj20101909 |
0.792 |
|
| 2011 |
So PP, Chen CD, Abraham CR. Detection of amyloid-β protein precursor homo-interactions using beta-galactosidase enzyme fragment complementation. Journal of Alzheimer's Disease : Jad. 26: 647-55. PMID 21694460 DOI: 10.3233/Jad-2011-110323 |
0.763 |
|
| 2010 |
Oh SY, Chen CD, Abraham CR. Cell-type dependent modulation of Notch signaling by the amyloid precursor protein. Journal of Neurochemistry. 113: 262-74. PMID 20089128 DOI: 10.1111/J.1471-4159.2010.06603.X |
0.7 |
|
| 2010 |
Abraham CR, Chen C, King GD. P3-469: Development of Klotho enhancers as novel therapeutics for Alzheimer's disease Alzheimer's & Dementia. 6: S591-S591. DOI: 10.1016/J.Jalz.2010.05.2012 |
0.691 |
|
| 2010 |
Chen C, Abraham CR. P2-291: The functions of the anti-aging protein Klotho in the brain Alzheimer's & Dementia. 6: S399-S399. DOI: 10.1016/J.Jalz.2010.05.1341 |
0.565 |
|
| 2008 |
Zerbinatti CV, Cordy JM, Chen CD, Guillily M, Suon S, Ray WJ, Seabrook GR, Abraham CR, Wolozin B. Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein. Molecular Neurodegeneration. 3: 5. PMID 18348724 DOI: 10.1186/1750-1326-3-5 |
0.604 |
|
| 2008 |
Hinman JD, Chen CD, Oh SY, Hollander W, Abraham CR. Age-dependent accumulation of ubiquitinated 2',3'-cyclic nucleotide 3'-phosphodiesterase in myelin lipid rafts. Glia. 56: 118-33. PMID 17963267 DOI: 10.1002/Glia.20595 |
0.756 |
|
| 2008 |
Abraham CR, Podvin S, King G, McKee A, Carreras I, Dedeoglu A, Chen C. O1-03-07: Klotho, aging and Alzheimer's Alzheimer's & Dementia. 4: T113-T114. DOI: 10.1016/J.Jalz.2008.05.235 |
0.768 |
|
| 2008 |
King GD, Chen C, Podvin S, Abraham CR. P4-186: Modulating Klotho expression to protect against age-induced neurodegeneration Alzheimer's & Dementia. 4: T725-T726. DOI: 10.1016/J.Jalz.2008.05.2253 |
0.778 |
|
| 2008 |
So P, Chen C, Abraham CR. P2-362: Detection of amyloid precursor protein dimerization in cells using enzyme fragment complementation and bimolecular fluorescent complementation Alzheimer's & Dementia. 4: T478-T479. DOI: 10.1016/J.Jalz.2008.05.1440 |
0.75 |
|
| 2007 |
Chen CD, Podvin S, Gillespie E, Leeman SE, Abraham CR. Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17. Proceedings of the National Academy of Sciences of the United States of America. 104: 19796-801. PMID 18056631 DOI: 10.1073/Pnas.0709805104 |
0.744 |
|
| 2006 |
Chen CD, Oh SY, Hinman JD, Abraham CR. Visualization of APP dimerization and APP-Notch2 heterodimerization in living cells using bimolecular fluorescence complementation. Journal of Neurochemistry. 97: 30-43. PMID 16515557 DOI: 10.1111/J.1471-4159.2006.03705.X |
0.749 |
|
| 2006 |
Cordy JM, Zerbinatti CV, Chen C, Guillily M, Ray WJ, Seabrook GR, Abraham CR, Wolozin B. P4-077: Modulation of amyloid precursor protein-processing by oxysterol-binding protein Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1815 |
0.567 |
|
| 2006 |
Chen C, Oh S, Abraham CR. P4-002: Bimolecular fluorescence complementation studies of APP homodimerization and heterodimerization Alzheimer's & Dementia. 2: S514-S514. DOI: 10.1016/J.Jalz.2006.05.1740 |
0.596 |
|
| 2005 |
Oh SY, Ellenstein A, Chen CD, Hinman JD, Berg EA, Costello CE, Yamin R, Neve RL, Abraham CR. Amyloid precursor protein interacts with notch receptors. Journal of Neuroscience Research. 82: 32-42. PMID 16118793 DOI: 10.1002/Jnr.20625 |
0.767 |
|
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