Frauke Melchior - Publications

Affiliations: 
1998 Heidelberg University, Tiffin, OH, United States 

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Correa-Vázquez JF, Juárez-Vicente F, García-Gutiérrez P, Barysch SV, Melchior F, García-Domínguez M. The Sumo proteome of proliferating and neuronal-differentiating cells reveals Utf1 among key Sumo targets involved in neurogenesis. Cell Death & Disease. 12: 305. PMID 33753728 DOI: 10.1038/s41419-021-03590-2  0.38
2016 Ritterhoff T, Das H, Hofhaus G, Schröder RR, Flotho A, Melchior F. The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes. Nature Communications. 7: 11482. PMID 27160050 DOI: 10.1038/ncomms11482  0.339
2015 Sakin V, Richter SM, Hsiao HH, Urlaub H, Melchior F. Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex. The Journal of Biological Chemistry. 290: 23589-602. PMID 26251516 DOI: 10.1074/jbc.M115.660118  0.35
2014 Barysch SV, Dittner C, Flotho A, Becker J, Melchior F. Identification and analysis of endogenous SUMO1 and SUMO2/3 targets in mammalian cells and tissues using monoclonal antibodies. Nature Protocols. 9: 896-909. PMID 24651501 DOI: 10.1038/nprot.2014.053  0.307
2013 Flotho A, Melchior F. Sumoylation: a regulatory protein modification in health and disease. Annual Review of Biochemistry. 82: 357-85. PMID 23746258 DOI: 10.1146/annurev-biochem-061909-093311  0.421
2013 Becker J, Barysch SV, Karaca S, Dittner C, Hsiao HH, Berriel Diaz M, Herzig S, Urlaub H, Melchior F. Detecting endogenous SUMO targets in mammalian cells and tissues. Nature Structural & Molecular Biology. 20: 525-31. PMID 23503365 DOI: 10.1038/nsmb.2526  0.306
2012 Tirard M, Hsiao HH, Nikolov M, Urlaub H, Melchior F, Brose N. In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 21122-7. PMID 23213215 DOI: 10.1073/pnas.1215366110  0.368
2012 Pilla E, Möller U, Sauer G, Mattiroli F, Melchior F, Geiss-Friedlander R. A novel SUMO1-specific interacting motif in dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation. The Journal of Biological Chemistry. 287: 44320-9. PMID 23152501 DOI: 10.1074/Jbc.M112.397224  0.338
2012 Schulz S, Chachami G, Kozaczkiewicz L, Winter U, Stankovic-Valentin N, Haas P, Hofmann K, Urlaub H, Ovaa H, Wittbrodt J, Meulmeester E, Melchior F. Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions. Embo Reports. 13: 930-8. PMID 22878415 DOI: 10.1038/Embor.2012.125  0.361
2012 Werner A, Melchior F. SUMO unloads the Kap114 cab. The Embo Journal. 31: 2439-40. PMID 22562150 DOI: 10.1038/emboj.2012.103  0.305
2010 Splinter D, Tanenbaum ME, Lindqvist A, Jaarsma D, Flotho A, Yu KL, Grigoriev I, Engelsma D, Haasdijk ED, Keijzer N, Demmers J, Fornerod M, Melchior F, Hoogenraad CC, Medema RH, et al. Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry Plos Biology. 8. PMID 20386726 DOI: 10.1371/Journal.Pbio.1000350  0.328
2009 Melchior F. Frauke Melchior: How SUMO wrestles other proteins. Interview by Caitlin Sedwick. The Journal of Cell Biology. 187: 586-7. PMID 19951911 DOI: 10.1083/jcb.1875pi  0.414
2008 Meulmeester E, Kunze M, Hsiao HH, Urlaub H, Melchior F. Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25. Molecular Cell. 30: 610-9. PMID 18538659 DOI: 10.1016/j.molcel.2008.03.021  0.372
2008 Hutten S, Flotho A, Melchior F, Kehlenbach RH. The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import. Molecular Biology of the Cell. 19: 2300-10. PMID 18305100 DOI: 10.1091/mbc.e07-12-1279  0.664
2007 Geiss-Friedlander R, Melchior F. Concepts in sumoylation: a decade on. Nature Reviews. Molecular Cell Biology. 8: 947-56. PMID 18000527 DOI: 10.1038/nrm2293  0.364
2005 Melchior F. Posttranslational modification with SUMO proteins Gbm Annual Fall Meeting Berlin/Potsdam 2005. 2005. DOI: 10.1240/SAV_GBM_2005_H_001467  0.427
2003 Melchior F, Schergaut M, Pichler A. SUMO: Ligases, isopeptidases and nuclear pores Trends in Biochemical Sciences. 28: 612-618. PMID 14607092 DOI: 10.1016/j.tibs.2003.09.002  0.518
2002 Melchior F, Hengst L. SUMO-1 and p53. Cell Cycle (Georgetown, Tex.). 1: 245-9. PMID 12429940  0.419
2002 Swaminathan S, Melchior F. Nucleocytoplasmic transport: more than the usual suspects. Developmental Cell. 3: 304-6. PMID 12361592  0.497
2002 Kirsh O, Seeler JS, Pichler A, Gast A, Müller S, Miska E, Mathieu M, Harel-Bellan A, Kouzarides T, Melchior F, Dejean A. The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase. The Embo Journal. 21: 2682-91. PMID 12032081 DOI: 10.1093/Emboj/21.11.2682  0.322
2002 Pichler A, Melchior F. Ubiquitin-related modifier SUMO1 and nucleocytoplasmic transport Traffic. 3: 381-387. PMID 12010456 DOI: 10.1034/j.1600-0854.2002.30601.x  0.502
2001 Sachdev S, Bruhn L, Sieber H, Pichler A, Melchior F, Grosschedl R. PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies. Genes & Development. 15: 3088-103. PMID 11731474 DOI: 10.1101/Gad.944801  0.371
2001 Melchior F. Ran GTPase cycle: oOne mechanism -- two functions. Current Biology : Cb. 11: R257-60. PMID 11413013 DOI: 10.1016/S0960-9822(01)00132-4  0.315
2001 Melchior F. SUMO--nonclassical ubiquitin. Annual Review of Cell and Developmental Biology. 16: 591-626. PMID 11031248 DOI: 10.1146/ANNUREV.CELLBIO.16.1.591  0.471
1998 Melchior F, Gerace L. Two-way trafficking with Ran. Trends in Cell Biology. 8: 175-9. PMID 9695834 DOI: 10.1016/S0962-8924(98)01252-5  0.628
1998 Melchior F. Nuclear protein import in a permeabilized cell assay. Methods in Molecular Biology (Clifton, N.J.). 88: 265-73. PMID 9664312 DOI: 10.1385/0-89603-487-9:265  0.504
1998 Bayer P, Arndt A, Metzger S, Mahajan R, Melchior F, Jaenicke R, Becker J. Structure determination of the small ubiquitin-related modifier SUMO-1. Journal of Molecular Biology. 280: 275-86. PMID 9654451 DOI: 10.1006/Jmbi.1998.1839  0.467
1998 Lee GW, Melchior F, Matunis MJ, Mahajan R, Tian Q, Anderson P. Modification of Ran GTPase-activating protein by the small ubiquitin-related modifier SUMO-1 requires Ubc9, an E2-type ubiquitin-conjugating enzyme homologue. The Journal of Biological Chemistry. 273: 6503-7. PMID 9497385 DOI: 10.1074/Jbc.273.11.6503  0.418
1998 Mahajan R, Gerace L, Melchior F. Molecular characterization of the SUMO-1 modification of RanGAP1 and its role in nuclear envelope association. The Journal of Cell Biology. 140: 259-70. PMID 9442102 DOI: 10.1083/Jcb.140.2.259  0.651
1997 Delphin C, Guan T, Melchior F, Gerace L. RanGTP targets p97 to RanBP2, a filamentous protein localized at the cytoplasmic periphery of the nuclear pore complex. Molecular Biology of the Cell. 8: 2379-90. PMID 9398662 DOI: 10.1091/Mbc.8.12.2379  0.618
1997 Mahajan R, Delphin C, Guan T, Gerace L, Melchior F. A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2. Cell. 88: 97-107. PMID 9019411 DOI: 10.1016/S0092-8674(00)81862-0  0.697
1995 Melchior F, Guan T, Paschal B, Gerace L. Biochemical and structural analysis of nuclear protein import. Cold Spring Harbor Symposia On Quantitative Biology. 60: 707-16. PMID 8824446 DOI: 10.1101/Sqb.1995.060.01.077  0.665
1995 Melchior F, Sweet DJ, Gerace L. Analysis of Ran/TC4 function in nuclear protein import. Methods in Enzymology. 257: 279-91. PMID 8583930 DOI: 10.1016/S0076-6879(95)57032-2  0.648
1995 Becker J, Melchior F, Gerke V, Bischoff FR, Ponstingl H, Wittinghofer A. RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae. The Journal of Biological Chemistry. 270: 11860-5. PMID 7744835 DOI: 10.1074/jbc.270.20.11860  0.45
1995 Melchior F, Gerace L. Mechanisms of nuclear protein import. Current Opinion in Cell Biology. 7: 310-8. PMID 7662359 DOI: 10.1016/0955-0674(95)80084-0  0.676
1995 Melchior F, Guan T, Yokoyama N, Nishimoto T, Gerace L. GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import. The Journal of Cell Biology. 131: 571-81. PMID 7593180 DOI: 10.1083/Jcb.131.3.571  0.68
1993 Melchior F, Weber K, Gerke V. A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif. Molecular Biology of the Cell. 4: 569-581. PMID 8374168 DOI: 10.1091/Mbc.4.6.569  0.382
1993 Melchior F, Paschal B, Evans J, Gerace L. Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor. The Journal of Cell Biology. 123: 1649-59. PMID 8276887 DOI: 10.1083/Jcb.123.6.1649  0.687
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