| Year |
Citation |
Score |
| 2024 |
Ducommun S, Jannig PR, Cervenka I, Murgia M, Mittenbühler MJ, Chernogubova E, Dias JM, Jude B, Correia JC, Van Vranken JG, Ocana-Santero G, Porsmyr-Palmertz M, McCann Haworth S, Martínez-Redondo V, Liu Z, ... ... Ruas JL, et al. Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition. Molecular Metabolism. 101912. PMID 38458566 DOI: 10.1016/j.molmet.2024.101912 |
0.636 |
|
| 2023 |
Caria I, Nunes MJ, Ciraci V, Carvalho AN, Ranito C, Santos SG, Gama MJ, Castro-Caldas M, Rodrigues CMP, Ruas JL, Rodrigues E. NPC1-like phenotype, with intracellular cholesterol accumulation and altered mTORC1 signaling in models of Parkinson's disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1870: 166980. PMID 38061599 DOI: 10.1016/j.bbadis.2023.166980 |
0.587 |
|
| 2023 |
Spratt J, Dias JM, Kolonelou C, Kiriako G, Engström E, Petrova E, Karampelias C, Cervenka I, Papanicolaou N, Lentini A, Reinius B, Andersson O, Ambrosetti E, Ruas JL, Teixeira AI. Multivalent insulin receptor activation using insulin-DNA origami nanostructures. Nature Nanotechnology. PMID 37813939 DOI: 10.1038/s41565-023-01507-y |
0.56 |
|
| 2023 |
Correia JC, Jannig PR, Gosztyla ML, Cervenka I, Ducommun S, Præstholm SM, Dumont K, Liu Z, Liang Q, Edsgärd D, Emanuelsson O, Gregorevic P, Westerblad H, Venckunas T, Brazaitis M, ... ... Ruas JL, et al. Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and regeneration. Biorxiv : the Preprint Server For Biology. PMID 37398033 DOI: 10.1101/2023.06.12.544338 |
0.647 |
|
| 2023 |
Luo Q, Pui HP, Chen J, Yu L, Jannig PR, Pei Y, Zhao L, Chen X, Petropoulos S, Ruas JL, Wu J, Deng Q. Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence. Cell Reports. 42: 112021. PMID 36848234 DOI: 10.1016/j.celrep.2023.112021 |
0.609 |
|
| 2023 |
Rodrigues JS, Faria-Pereira A, Camões SP, Serras AS, Morais VA, Ruas JL, Miranda JP. Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signaling. Frontiers in Endocrinology. 13: 1043543. PMID 36714559 DOI: 10.3389/fendo.2022.1043543 |
0.59 |
|
| 2022 |
Tuomainen T, Naumenko N, Mutikainen M, Shakirzyanova A, Sczelecki S, Estall JL, Ruas JL, Tavi P. PGC-1α4 Interacts with REST to Upregulate Neuronal Genes and Augment Energy Consumption in Developing Cardiomyocytes. Cells. 11. PMID 36230906 DOI: 10.3390/cells11192944 |
0.766 |
|
| 2022 |
Li S, Li W, Yuan J, Bullova P, Wu J, Zhang X, Liu Y, Plescher M, Rodriguez J, Bedoya-Reina OC, Jannig PR, Valente-Silva P, Yu M, Henriksson MA, Zubarev RA, ... ... Ruas JL, et al. Publisher Correction: Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome. Nature Metabolism. PMID 36076077 DOI: 10.1038/s42255-022-00651-4 |
0.586 |
|
| 2022 |
Schihada H, Klompstra TM, Humphrys LJ, Cervenka I, Dadvar S, Kolb P, Ruas JL, Schulte G. Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias. The Journal of Biological Chemistry. 102328. PMID 35933013 DOI: 10.1016/j.jbc.2022.102328 |
0.601 |
|
| 2022 |
Oehler D, Spychala A, Gödecke A, Lang A, Gerdes N, Ruas J, Kelm M, Szendroedi J, Westenfeld R. Full-length transcriptomic analysis in murine and human heart reveals diversity of PGC-1α promoters and isoforms regulated distinctly in myocardial ischemia and obesity. Bmc Biology. 20: 169. PMID 35907957 DOI: 10.1186/s12915-022-01360-w |
0.652 |
|
| 2022 |
Li S, Li W, Yuan J, Bullova P, Wu J, Zhang X, Liu Y, Plescher M, Rodriguez J, Bedoya-Reina OC, Jannig PR, Valente-Silva P, Yu M, Henriksson MA, Zubarev RA, ... Ruas JL, et al. Impaired oxygen-sensitive regulation of mitochondrial biogenesis within the von Hippel-Lindau syndrome. Nature Metabolism. 4: 739-758. PMID 35760869 DOI: 10.1038/s42255-022-00593-x |
0.6 |
|
| 2022 |
Jannig PR, Dumesic PA, Spiegelman BM, Ruas JL. SnapShot: Regulation and biology of PGC-1α. Cell. 185: 1444-1444.e1. PMID 35427500 DOI: 10.1016/j.cell.2022.03.027 |
0.71 |
|
| 2022 |
Ilegems E, Bryzgalova G, Correia J, Yesildag B, Berra E, Ruas JL, Pereira TS, Berggren PO. HIF-1α inhibitor PX-478 preserves pancreatic β cell function in diabetes. Science Translational Medicine. 14: eaba9112. PMID 35353540 DOI: 10.1126/scitranslmed.aba9112 |
0.729 |
|
| 2021 |
Jonsson WO, Ponette J, Horwath O, Rydenstam T, Söderlund K, Ekblom B, Azzolini M, Ruas JL, Blomstrand E. Changes in plasma concentration of kynurenine following intake of branched-chain amino acids are not caused by alterations in muscle kynurenine metabolism. American Journal of Physiology. Cell Physiology. PMID 34817270 DOI: 10.1152/ajpcell.00285.2021 |
0.636 |
|
| 2021 |
Liu Z, Chaillou T, Santos Alves E, Mader T, Jude B, Ferreira DMS, Hynynen H, Cheng AJ, Jonsson WO, Pironti G, Andersson DC, Kenne E, Ruas JL, Tavi P, Lanner JT. Mitochondrial NDUFA4L2 is a novel regulator of skeletal muscle mass and force. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e22010. PMID 34724256 DOI: 10.1096/fj.202100066R |
0.658 |
|
| 2021 |
Massart J, Sjögren RJO, Egan B, Garde C, Lindgren M, Gu W, Ferreira DMS, Katayama M, Ruas JL, Barrès R, O'Gorman DJ, Zierath JR, Krook A. Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism. Nature Communications. 12: 5948. PMID 34642330 DOI: 10.1038/s41467-021-26095-0 |
0.622 |
|
| 2021 |
Correia JC, Kelahmetoglu Y, Jannig PR, Schweingruber C, Shvaikovskaya D, Zhengye L, Cervenka I, Khan N, Stec M, Oliveira M, Nijssen J, Martínez-Redondo V, Ducommun S, Azzolini M, Lanner JT, ... ... Ruas JL, et al. Muscle-secreted neurturin couples myofiber oxidative metabolism and slow motor neuron identity. Cell Metabolism. PMID 34592133 DOI: 10.1016/j.cmet.2021.09.003 |
0.648 |
|
| 2021 |
Valente-Silva P, Cervenka I, Ferreira DMS, Correia JC, Edman S, Horwath O, Heng B, Chow S, Jacobs KR, Guillemin GJ, Blomstrand E, Ruas JL. Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans. Metabolites. 11. PMID 34436450 DOI: 10.3390/metabo11080508 |
0.618 |
|
| 2021 |
Joisten N, Ruas JL, Braidy N, Guillemin GJ, Zimmer P. The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force? Trends in Molecular Medicine. PMID 34373202 DOI: 10.1016/j.molmed.2021.07.006 |
0.59 |
|
| 2021 |
Naumenko N, Mutikainen M, Holappa L, Ruas JL, Tuomainen T, Tavi P. PGC-1α deficiency reveals sex-specific links between cardiac energy metabolism and EC-coupling during development of heart failure in mice. Cardiovascular Research. PMID 34086875 DOI: 10.1093/cvr/cvab188 |
0.601 |
|
| 2021 |
Naia L, Pinho CM, Dentoni G, Liu J, Leal NS, Ferreira DMS, Schreiner B, Filadi R, Fão L, Connolly NMC, Forsell P, Nordvall G, Shimozawa M, Greotti E, Basso E, ... ... Ruas JL, et al. Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling. Bmc Biology. 19: 57. PMID 33761951 DOI: 10.1186/s12915-021-00979-5 |
0.583 |
|
| 2021 |
Moberg M, Apró W, Cervenka I, Ekblom B, van Hall G, Holmberg HC, Ruas JL, Blomstrand E. High-intensity leg cycling alters the molecular response to resistance exercise in the arm muscles. Scientific Reports. 11: 6453. PMID 33742064 DOI: 10.1038/s41598-021-85733-1 |
0.618 |
|
| 2021 |
Song KY, Correia J, Ruas JL, Teixeira AI. Effects of topological constraints on the alignment and maturation of multinucleated myotubes. Biotechnology and Bioengineering. PMID 33629347 DOI: 10.1002/bit.27731 |
0.616 |
|
| 2021 |
Wu H, Petitpré C, Fontanet P, Sharma A, Bellardita C, Quadros RM, Jannig PR, Wang Y, Heimel JA, Cheung KKY, Wanderoy S, Xuan Y, Meletis K, Ruas J, Gurumurthy CB, et al. Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice. Nature Communications. 12: 1026. PMID 33589589 DOI: 10.1038/s41467-021-21173-9 |
0.587 |
|
| 2020 |
Kelahmetoglu Y, Jannig PR, Cervenka I, Koch LG, Britton SL, Zhou J, Wang H, Robinson MM, Nair KS, Ruas JL. Comparative Analysis of Skeletal Muscle Transcriptional Signatures Associated With Aerobic Exercise Capacity or Response to Training in Humans and Rats. Frontiers in Endocrinology. 11: 591476. PMID 33193103 DOI: 10.3389/fendo.2020.591476 |
0.645 |
|
| 2020 |
Hahn M, van Krieken PP, Nord C, Alanentalo T, Morini F, Xiong Y, Eriksson M, Mayer J, Kostromina E, Ruas JL, Sharpe J, Pereira T, Berggren PO, Ilegems E, Ahlgren U. Topologically selective islet vulnerability and self-sustained downregulation of markers for β-cell maturity in streptozotocin-induced diabetes. Communications Biology. 3: 541. PMID 32999405 DOI: 10.1038/s42003-020-01243-2 |
0.71 |
|
| 2020 |
Seiger Cronfalk B, Åkesson E, Nygren J, Nyström A, Strandell AM, Ruas J, von Euler M. A qualitative study-Patient experience of tactile massage after stroke. Nursing Open. 7: 1446-1452. PMID 32802364 DOI: 10.1002/nop2.515 |
0.518 |
|
| 2020 |
Alves CRR, Neves WD, de Almeida NR, Eichelberger EJ, Jannig PR, Voltarelli VA, Tobias GC, Bechara LRG, de P Faria D, Alves MJN, Hagen L, Sharma A, Slupphaug G, Moreira JBN, Wisloff U, ... ... Ruas JL, et al. Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN. Molecular Metabolism. 101012. PMID 32408015 DOI: 10.1016/J.Molmet.2020.101012 |
0.614 |
|
| 2020 |
Correia JC, Ruas JL. Exercised cytokines promote endurance. Science (New York, N.Y.). 368: 470-471. PMID 32355018 DOI: 10.1126/science.abb4116 |
0.597 |
|
| 2020 |
Martin K, Azzolini M, Ruas JL. The Kynurenine connection: how exercise shifts muscle tryptophan metabolism and affects energy homeostasis, the immune system, and the brain. American Journal of Physiology. Cell Physiology. PMID 32208989 DOI: 10.1152/ajpcell.00580.2019 |
0.656 |
|
| 2020 |
Léveillé M, Besse-Patin A, Jouvet N, Gunes A, Sczelecki S, Jeromson S, Khan NP, Baldwin C, Dumouchel A, Correia JC, Jannig PR, Boulais J, Ruas JL, Estall JL. PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments. Molecular Metabolism. 34: 72-84. PMID 32180561 DOI: 10.1016/j.molmet.2020.01.004 |
0.768 |
|
| 2020 |
Taylor-Weiner H, Grigsby CL, Ferreira DMS, Dias JM, Stevens MM, Ruas JL, Teixeira AI. Modeling the transport of nuclear proteins along single skeletal muscle cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31988126 DOI: 10.1073/Pnas.1919600117 |
0.626 |
|
| 2019 |
Peleli M, Ferreira DMS, Tarnawski L, McCann Haworth S, Xuechen L, Zhuge Z, Newton PT, Massart J, Chagin AS, Olofsson PS, Ruas JL, Weitzberg E, Lundberg JO, Carlström M. Dietary nitrate attenuates high-fat diet-induced obesity via mechanisms involving higher adipocyte respiration and alterations in inflammatory status. Redox Biology. 28: 101387. PMID 31765889 DOI: 10.1016/j.redox.2019.101387 |
0.624 |
|
| 2019 |
Ferreira DMS, Cheng AJ, Agudelo LZ, Cervenka I, Chaillou T, Correia JC, Porsmyr-Palmertz M, Izadi M, Hansson A, Martínez-Redondo V, Valente-Silva P, Pettersson-Klein AT, Estall JL, Robinson MM, Nair KS, ... ... Ruas JL, et al. LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force. Skeletal Muscle. 9: 26. PMID 31666122 DOI: 10.1186/S13395-019-0214-1 |
0.752 |
|
| 2019 |
Agudelo LZ, Ferreira DMS, Dadvar S, Cervenka I, Ketscher L, Izadi M, Zhengye L, Furrer R, Handschin C, Venckunas T, Brazaitis M, Kamandulis S, Lanner JT, Ruas JL. Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance. Nature Communications. 10: 2767. PMID 31235694 DOI: 10.1038/s41467-019-10712-0 |
0.678 |
|
| 2019 |
Carvalho A, Ranito C, Tavares C, Castro-Caldas M, Rodrigues E, Ruas J, Van Horssen J, Gama M. Activation of the Unfolded Protein Response in Parkinson's disease Frontiers in Cellular Neuroscience. 13. DOI: 10.3389/Conf.Fncel.2019.01.00051 |
0.555 |
|
| 2019 |
Nunes M, Caria I, Carvalho A, Costa D, Castro-Caldas M, Gama M, Rodrigues E, Ruas J. Unanswered role of cholesterol homeostasis in Parkinson’s disease Frontiers in Cellular Neuroscience. 13. DOI: 10.3389/Conf.Fncel.2019.01.00024 |
0.546 |
|
| 2018 |
Blackwell TA, Cervenka I, Khatri B, Brown JL, Rosa-Caldwell ME, Lee DE, Perry RA, Brown LA, Haynie WS, Wiggs MP, Bottje WG, Washington TA, Kong BC, Ruas JL, Greene NP. A Transcriptomic Analysis of the Development of Skeletal Muscle Atrophy in Cancer-Cachexia in Tumor-Bearing Mice. Physiological Genomics. PMID 30289747 DOI: 10.1152/Physiolgenomics.00061.2018 |
0.642 |
|
| 2018 |
Dadvar S, Ferreira DMS, Cervenka I, Ruas JL. The weight of nutrients: kynurenine metabolites in obesity and exercise. Journal of Internal Medicine. PMID 30141532 DOI: 10.1111/joim.12830 |
0.63 |
|
| 2018 |
Bayindir-Buchhalter I, Wolff G, Lerch S, Sijmonsma T, Schuster M, Gronych J, Billeter AT, Babaei R, Krunic D, Ketscher L, Spielmann N, Hrabe de Angelis M, Ruas JL, Müller-Stich BP, Heikenwalder M, et al. Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors. Embo Molecular Medicine. 10. PMID 29973382 DOI: 10.15252/emmm.201708613 |
0.618 |
|
| 2018 |
Kärkkäinen O, Tuomainen T, Mutikainen M, Lehtonen M, Ruas JL, Hanhineva K, Tavi P. Heart specific PGC-1α deletion identifies metabolome of cardiac restricted metabolic heart failure. Cardiovascular Research. PMID 29931052 DOI: 10.1093/Cvr/Cvy155 |
0.588 |
|
| 2018 |
Pettersson-Klein AT, Izadi M, Ferreira DMS, Cervenka I, Correia JC, Martinez-Redondo V, Southern M, Cameron M, Kamenecka T, Agudelo LZ, Porsmyr-Palmertz M, Martens U, Lundgren B, Otrocka M, Jenmalm-Jensen A, ... ... Ruas JL, et al. Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration. Molecular Metabolism. PMID 29428596 DOI: 10.1016/j.molmet.2018.01.017 |
0.644 |
|
| 2018 |
Agudelo LZ, Ferreira DMS, Cervenka I, Bryzgalova G, Dadvar S, Jannig PR, Pettersson-Klein AT, Lakshmikanth T, Sustarsic EG, Porsmyr-Palmertz M, Correia JC, Izadi M, Martínez-Redondo V, Ueland PM, Midttun Ø, ... ... Ruas JL, et al. Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation. Cell Metabolism. 27: 378-392.e5. PMID 29414686 DOI: 10.1016/j.cmet.2018.01.004 |
0.759 |
|
| 2017 |
Mills R, Taylor-Weiner H, Correia JC, Agudelo LZ, Allodi I, Kolonelou C, Martinez-Redondo V, Ferreira DMS, Nichterwitz S, Comley LH, Lundin V, Hedlund E, Ruas JL, Teixeira AI. Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation. Molecular Metabolism. PMID 29157948 DOI: 10.1016/J.Molmet.2017.11.001 |
0.621 |
|
| 2017 |
Cervenka I, Agudelo LZ, Ruas JL. Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health. Science (New York, N.Y.). 357. PMID 28751584 DOI: 10.1126/science.aaf9794 |
0.641 |
|
| 2017 |
Ruby MA, Massart J, Hunerdosse DM, Schönke M, Correia JC, Louie SM, Ruas JL, Näslund E, Nomura DK, Zierath JR. Human Carboxylesterase 2 Reverses Obesity-Induced Diacylglycerol Accumulation and Glucose Intolerance. Cell Reports. 18: 636-646. PMID 28099843 DOI: 10.1016/J.Celrep.2016.12.070 |
0.586 |
|
| 2016 |
Cipriano M, Correia JC, Camões SP, Oliveira NG, Cruz P, Cruz H, Castro M, Ruas JL, Santos JM, Miranda JP. The role of epigenetic modifiers in extended cultures of functional hepatocyte-like cells derived from human neonatal mesenchymal stem cells. Archives of Toxicology. PMID 27909741 DOI: 10.1007/s00204-016-1901-x |
0.596 |
|
| 2016 |
Mutikainen M, Tuomainen T, Naumenko N, Huusko J, Smirin B, Laidinen S, Kokki K, Hynynen H, Ylä-Herttuala S, Heinäniemi M, Ruas JL, Tavi P. PGC-1α1 induces cardiac excitation-contraction coupling phenotype without metabolic remodelling. The Journal of Physiology. PMID 27716916 DOI: 10.1113/JP272847 |
0.65 |
|
| 2016 |
Moutinho M, Nunes MJ, Correia JC, Gama MJ, Castro-Caldas M, Cedazo-Minguez A, Rodrigues CM, Björkhem I, Ruas JL, Rodrigues E. Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk. Scientific Reports. 6: 30928. PMID 27491694 DOI: 10.1038/srep30928 |
0.581 |
|
| 2016 |
Salah H, Li M, Cacciani N, Gastaldello S, Ogilvie H, Akkad H, Namuduri AV, Morbidoni V, Artemenko KA, Balogh G, Martinez-Redondo V, Jannig P, Hedström Y, Dworkin B, Bergquist J, ... Ruas J, et al. The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction. Science Translational Medicine. 8: 350ra103. PMID 27488897 DOI: 10.1126/Scitranslmed.Aaf7099 |
0.602 |
|
| 2016 |
Jannig PR, Ruas JL. Targeting mitochondrial mRNA translation to tackle obesity-induced insulin resistance: thumbs up for exercise. Acta Physiologica (Oxford, England). 219: 14-16. PMID 27419811 DOI: 10.1111/apha.12752 |
0.602 |
|
| 2016 |
Martinez-Redondo V, Jannig PR, Correia JC, Ferreira DM, Cervenka I, Lindvall JM, Sinha I, Izadi M, Pettersson-Klein AT, Agudelo LZ, Gimenez-Cassina A, Brum PC, Dahlman-Wright K, Ruas JL. Peroxisome proliferator-activated receptor gamma coactivator-1alpha isoforms selectively regulate multiple splicing events on target genes. The Journal of Biological Chemistry. PMID 27231350 DOI: 10.1074/Jbc.M115.705822 |
0.599 |
|
| 2016 |
Schlittler M, Goiny M, Agudelo LZ, Venckunas T, Brazaitis M, Skurvydas A, Kamandulis S, Ruas JL, Erhardt S, Westerblad H, Andersson DC. Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans. American Journal of Physiology. Cell Physiology. 310: C836-40. PMID 27030575 DOI: 10.1152/ajpcell.00053.2016 |
0.626 |
|
| 2016 |
Kalamgi RC, Salah H, Gastaldello S, Martinez-Redondo V, Ruas J, Fury W, Bai Y, Gromada J, Sartori R, Guttridge DC, Sandri M, Larsson L. Mechano signaling pathways in an experimental intensive critical illness myopathy model. The Journal of Physiology. PMID 26990577 DOI: 10.1113/JP271973 |
0.618 |
|
| 2016 |
Zepf FD, Stewart RM, Guillemin G, Ruas JL. Inflammation, immunology, stress and depression: a role for kynurenine metabolism in physical exercise and skeletal muscle Acta Neuropsychiatrica. 1-2. DOI: 10.1017/neu.2015.69 |
0.626 |
|
| 2016 |
Chaillou T, Hynynen H, Ferreira D, Pironti G, Kenne E, Andersson DC, Ruas JL, Tavi P, Lanner JT. NDUFA4L2 – Connecting Metabolic Signals and Mitochondrial Function in Cardiac and Skeletal Muscle Free Radical Biology and Medicine. 100: S186. DOI: 10.1016/j.freeradbiomed.2016.10.511 |
0.632 |
|
| 2015 |
Correia JC, Massart J, de Boer JF, Porsmyr-Palmertz M, Martínez-Redondo V, Agudelo LZ, Sinha I, Meierhofer D, Ribeiro V, Björnholm M, Sauer S, Dahlman-Wright K, Zierath JR, Groen AK, Ruas JL. Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism. Molecular Metabolism. 4: 891-902. PMID 26909306 DOI: 10.1016/J.Molmet.2015.09.005 |
0.595 |
|
| 2015 |
Place N, Ivarsson N, Venckunas T, Neyroud D, Brazaitis M, Cheng AJ, Ochala J, Kamandulis S, Girard S, Volungevičius G, Paužas H, Mekideche A, Kayser B, Martinez-Redondo V, Ruas JL, et al. Ryanodine receptor fragmentation and sarcoplasmic reticulum Ca2+ leak after one session of high-intensity interval exercise. Proceedings of the National Academy of Sciences of the United States of America. PMID 26575622 DOI: 10.1073/pnas.1507176112 |
0.63 |
|
| 2015 |
Martínez-Redondo V, Pettersson AT, Ruas JL. The hitchhiker's guide to PGC-1α isoform structure and biological functions. Diabetologia. 58: 1969-77. PMID 26109214 DOI: 10.1007/s00125-015-3671-z |
0.627 |
|
| 2015 |
Correia JC, Ferreira DM, Ruas JL. Intercellular: local and systemic actions of skeletal muscle PGC-1s. Trends in Endocrinology and Metabolism: Tem. 26: 305-14. PMID 25934582 DOI: 10.1016/j.tem.2015.03.010 |
0.677 |
|
| 2015 |
Correia JC, Massart J, de Boer JF, Porsmyr-Palmertz M, Martínez-Redondo V, Agudelo LZ, Sinha I, Meierhofer D, Ribeiro V, Björnholm M, Sauer S, Dahlman-Wright K, Zierath JR, Groen AK, Ruas JL. Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism Molecular Metabolism. DOI: 10.1016/j.molmet.2015.09.005 |
0.574 |
|
| 2014 |
White JP, Wrann CD, Rao RR, Nair SK, Jedrychowski MP, You JS, MartÃnez-Redondo V, Gygi SP, Ruas JL, Hornberger TA, Wu Z, Glass DJ, Piao X, Spiegelman BM. G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 111: 15756-61. PMID 25336758 DOI: 10.1073/Pnas.1417898111 |
0.745 |
|
| 2014 |
Agudelo LZ, Femenía T, Orhan F, Porsmyr-Palmertz M, Goiny M, Martinez-Redondo V, Correia JC, Izadi M, Bhat M, Schuppe-Koistinen I, Pettersson AT, Ferreira DM, Krook A, Barres R, Zierath JR, ... ... Ruas JL, et al. Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression. Cell. 159: 33-45. PMID 25259918 DOI: 10.1016/j.cell.2014.07.051 |
0.643 |
|
| 2014 |
Rao RR, Long JZ, White JP, Svensson KJ, Lou J, Lokurkar I, Jedrychowski MP, Ruas JL, Wrann CD, Lo JC, Camera DM, Lachey J, Gygi S, Seehra J, Hawley JA, et al. Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis. Cell. 157: 1279-91. PMID 24906147 DOI: 10.1016/J.Cell.2014.03.065 |
0.797 |
|
| 2014 |
Aesoy R, Gradin K, Aasrud KS, Hoivik EA, Ruas JL, Poellinger L, Bakke M. Regulation of CDKN2B expression by interaction of Arnt with Miz-1--a basis for functional integration between the HIF and Myc gene regulatory pathways. Molecular Cancer. 13: 54. PMID 24618291 DOI: 10.1186/1476-4598-13-54 |
0.714 |
|
| 2014 |
Sczelecki S, Besse-Patin A, Abboud A, Kleiner S, Laznik-Bogoslavski D, Wrann CD, Ruas JL, Haibe-Kains B, Estall JL. Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation. American Journal of Physiology. Endocrinology and Metabolism. 306: E157-67. PMID 24280126 DOI: 10.1152/ajpendo.00578.2013 |
0.776 |
|
| 2012 |
Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, et al. A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy. Cell. 151: 1319-31. PMID 23217713 DOI: 10.1016/J.Cell.2012.10.050 |
0.816 |
|
| 2011 |
Lustig Y, Ruas JL, Estall JL, Lo JC, Devarakonda S, Laznik D, Choi JH, Ono H, Olsen JV, Spiegelman BM. Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase. Genes & Development. 25: 1232-44. PMID 21646374 DOI: 10.1101/Gad.2054711 |
0.791 |
|
| 2011 |
Wu J, Ruas JL, Estall JL, Rasbach KA, Choi JH, Ye L, Boström P, Tyra HM, Crawford RW, Campbell KP, Rutkowski DT, Kaufman RJ, Spiegelman BM. The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex. Cell Metabolism. 13: 160-9. PMID 21284983 DOI: 10.1016/J.Cmet.2011.01.003 |
0.806 |
|
| 2010 |
Rasbach KA, Gupta RK, Ruas JL, Wu J, Naseri E, Estall JL, Spiegelman BM. PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types. Proceedings of the National Academy of Sciences of the United States of America. 107: 21866-71. PMID 21106753 DOI: 10.1073/Pnas.1016089107 |
0.813 |
|
| 2010 |
Chakkalakal JV, Nishimune H, Ruas JL, Spiegelman BM, Sanes JR. Retrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneurons. Development (Cambridge, England). 137: 3489-99. PMID 20843861 DOI: 10.1242/dev.053348 |
0.676 |
|
| 2010 |
Choi JH, Banks AS, Estall JL, Kajimura S, Boström P, Laznik D, Ruas JL, Chalmers MJ, Kamenecka TM, Blüher M, Griffin PR, Spiegelman BM. Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5. Nature. 466: 451-6. PMID 20651683 DOI: 10.1038/Nature09291 |
0.771 |
|
| 2010 |
Ruas JL, Berchner-Pfannschmidt U, Malik S, Gradin K, Fandrey J, Roeder RG, Pereira T, Poellinger L. Complex regulation of the transactivation function of hypoxia-inducible factor-1 alpha by direct interaction with two distinct domains of the CREB-binding protein/p300. The Journal of Biological Chemistry. 285: 2601-9. PMID 19880525 DOI: 10.1074/jbc.M109.021824 |
0.789 |
|
| 2009 |
Estall JL, Ruas JL, Choi CS, Laznik D, Badman M, Maratos-Flier E, Shulman GI, Spiegelman BM. PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis. Proceedings of the National Academy of Sciences of the United States of America. 106: 22510-5. PMID 20018698 DOI: 10.1073/Pnas.0912533106 |
0.795 |
|
| 2009 |
Chinsomboon J, Ruas J, Gupta RK, Thom R, Shoag J, Rowe GC, Sawada N, Raghuram S, Arany Z. The transcriptional coactivator PGC-1alpha mediates exercise-induced angiogenesis in skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. 106: 21401-6. PMID 19966219 DOI: 10.1073/Pnas.0909131106 |
0.775 |
|
| 2008 |
Kajimura S, Seale P, Tomaru T, Erdjument-Bromage H, Cooper MP, Ruas JL, Chin S, Tempst P, Lazar MA, Spiegelman BM. Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes & Development. 22: 1397-409. PMID 18483224 DOI: 10.1101/Gad.1666108 |
0.789 |
|
| 2008 |
Zheng X, Linke S, Dias JM, Zheng X, Gradin K, Wallis TP, Hamilton BR, Gustafsson M, Ruas JL, Wilkins S, Bilton RL, Brismar K, Whitelaw ML, Pereira T, Gorman JJ, et al. Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways. Proceedings of the National Academy of Sciences of the United States of America. 105: 3368-73. PMID 18299578 DOI: 10.1073/pnas.0711591105 |
0.791 |
|
| 2008 |
Arany Z, Foo SY, Ma Y, Ruas JL, Bommi-Reddy A, Girnun G, Cooper M, Laznik D, Chinsomboon J, Rangwala SM, Baek KH, Rosenzweig A, Spiegelman BM. HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1alpha. Nature. 451: 1008-12. PMID 18288196 DOI: 10.1038/nature06613 |
0.728 |
|
| 2007 |
Ruas JL, Lendahl U, Poellinger L. Modulation of vascular gene expression by hypoxia. Current Opinion in Lipidology. 18: 508-14. PMID 17885420 DOI: 10.1097/MOL.0b013e3282efe49d |
0.725 |
|
| 2007 |
Ronkainen VP, Ronkainen JJ, Hänninen SL, Leskinen H, Ruas JL, Pereira T, Poellinger L, Vuolteenaho O, Tavi P. Hypoxia inducible factor regulates the cardiac expression and secretion of apelin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1821-30. PMID 17341685 DOI: 10.1096/Fj.06-7294Com |
0.783 |
|
| 2006 |
Zheng X, Ruas JL, Cao R, Salomons FA, Cao Y, Poellinger L, Pereira T. Cell-type-specific regulation of degradation of hypoxia-inducible factor 1 alpha: role of subcellular compartmentalization. Molecular and Cellular Biology. 26: 4628-41. PMID 16738327 DOI: 10.1128/MCB.02236-05 |
0.786 |
|
| 2005 |
Gustafsson MV, Zheng X, Pereira T, Gradin K, Jin S, Lundkvist J, Ruas JL, Poellinger L, Lendahl U, Bondesson M. Hypoxia requires notch signaling to maintain the undifferentiated cell state. Developmental Cell. 9: 617-28. PMID 16256737 DOI: 10.1016/j.devcel.2005.09.010 |
0.791 |
|
| 2005 |
Ruas JL, Poellinger L. Hypoxia-dependent activation of HIF into a transcriptional regulator. Seminars in Cell & Developmental Biology. 16: 514-22. PMID 15908239 DOI: 10.1016/j.semcdb.2005.04.001 |
0.73 |
|
| 2005 |
Ruas JL, Poellinger L, Pereira T. Role of CBP in regulating HIF-1-mediated activation of transcription. Journal of Cell Science. 118: 301-11. PMID 15615775 DOI: 10.1242/jcs.01617 |
0.791 |
|
| 2003 |
Pereira T, Zheng X, Ruas JL, Tanimoto K, Poellinger L. Identification of residues critical for regulation of protein stability and the transactivation function of the hypoxia-inducible factor-1alpha by the von Hippel-Lindau tumor suppressor gene product. The Journal of Biological Chemistry. 278: 6816-23. PMID 12468553 DOI: 10.1074/jbc.M209297200 |
0.785 |
|
| 2002 |
Ruas JL, Poellinger L, Pereira T. Functional analysis of hypoxia-inducible factor-1 alpha-mediated transactivation. Identification of amino acid residues critical for transcriptional activation and/or interaction with CREB-binding protein. The Journal of Biological Chemistry. 277: 38723-30. PMID 12133832 DOI: 10.1074/jbc.M205051200 |
0.782 |
|
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