Year |
Citation |
Score |
2023 |
Qi M, Ma S, Liu J, Liu X, Wei J, Lu WJ, Zhang S, Chang Y, Zhang Y, Zhong K, Yan Y, Zhu M, Song Y, Chen Y, Hao G, ... ... Wang Y, et al. In Vivo Base Editing of Scn5a Rescues Type 3 Long QT Syndrome in Mice. Circulation. PMID 37965733 DOI: 10.1161/CIRCULATIONAHA.123.065624 |
0.525 |
|
2023 |
Wang Y, Qi T, Liu J, Yang Y, Wang Z, Wang Y, Wang T, Li M, Li M, Lu D, Chang ACY, Yang L, Gao S, Wang Y, Lan F. A highly specific CRISPR-Cas12j nuclease enables allele-specific genome editing. Science Advances. 9: eabo6405. PMID 36763662 DOI: 10.1126/sciadv.abo6405 |
0.533 |
|
2022 |
Wang S, Tao C, Mao H, Hou L, Wang Y, Qi T, Yang Y, Ong SG, Hu S, Chai R, Wang Y. Identification of SaCas9 orthologs containing a conserved serine residue that determines simple NNGG PAM recognition. Plos Biology. 20: e3001897. PMID 36449487 DOI: 10.1371/journal.pbio.3001897 |
0.521 |
|
2022 |
Saleem A, Abbas MK, Wang Y, Lan F. hPSC gene editing for cardiac disease therapy. Pflugers Archiv : European Journal of Physiology. PMID 36163402 DOI: 10.1007/s00424-022-02751-2 |
0.614 |
|
2021 |
Wang S, Mao H, Hou L, Hu Z, Wang Y, Qi T, Tao C, Yang Y, Zhang C, Li M, Liu H, Hu S, Chai R, Wang Y. Compact SchCas9 Recognizes the Simple NNGR PAM. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2104789. PMID 34874112 DOI: 10.1002/advs.202104789 |
0.548 |
|
2021 |
Ma S, Jiang W, Liu X, Lu WJ, Qi T, Wei J, Wu F, Chang Y, Zhang S, Song Y, Bai R, Wang J, Lee A, Zhang H, Wang Y, et al. Efficient Correction of a Hypertrophic Cardiomyopathy Mutation by ABEmax-NG. Circulation Research. PMID 34525843 DOI: 10.1161/CIRCRESAHA.120.318674 |
0.541 |
|
2021 |
Ye L, Yu Y, Zhao ZA, Zhao D, Ni X, Wang Y, Fang X, Yu M, Wang Y, Tang JM, Chen Y, Shen Z, Lei W, Hu S. Patient-specific iPSC-derived cardiomyocytes reveal abnormal regulation of FGF16 in a familial atrial septal defect. Cardiovascular Research. PMID 33956078 DOI: 10.1093/cvr/cvab154 |
0.593 |
|
2021 |
Hu Z, Zhang C, Wang S, Gao S, Wei J, Li M, Hou L, Mao H, Wei Y, Qi T, Liu H, Liu D, Lan F, Lu D, Wang H, ... ... Wang Y, et al. Discovery and engineering of small SlugCas9 with broad targeting range and high specificity and activity. Nucleic Acids Research. PMID 33721016 DOI: 10.1093/nar/gkab148 |
0.54 |
|
2020 |
Li Y, Chang Y, Li X, Li X, Gao J, Zhou Y, Wu F, Bai R, Dong T, Ma S, Zhang S, Lu WJ, Tan X, Wang Y, Lan F. RAD-Deficient Human Cardiomyocytes Develop Hypertrophic Cardiomyopathy Phenotypes Due to Calcium Dysregulation. Frontiers in Cell and Developmental Biology. 8: 585879. PMID 33195237 DOI: 10.3389/fcell.2020.585879 |
0.548 |
|
2020 |
Qi T, Wu F, Xie Y, Gao S, Li M, Pu J, Li D, Lan F, Wang Y. Base Editing Mediated Generation of Point Mutations Into Human Pluripotent Stem Cells for Modeling Disease. Frontiers in Cell and Developmental Biology. 8: 590581. PMID 33102492 DOI: 10.3389/fcell.2020.590581 |
0.606 |
|
2020 |
Han X, Zhao ZA, Yan S, Lei W, Wu H, Lu XA, Chen Y, Li J, Wang Y, Yu M, Wang Y, Zheng Y, Wang H, Shen Z, Hu S. CXADR-like membrane protein protects against heart injury by preventing excessive pyroptosis after myocardial infarction. Journal of Cellular and Molecular Medicine. PMID 33084169 DOI: 10.1111/jcmm.15955 |
0.508 |
|
2020 |
Hu Z, Wang S, Zhang C, Gao N, Li M, Wang D, Wang D, Liu D, Liu H, Ong SG, Wang H, Wang Y. A compact Cas9 ortholog from Staphylococcus Auricularis (SauriCas9) expands the DNA targeting scope. Plos Biology. 18: e3000686. PMID 32226015 DOI: 10.1371/journal.pbio.3000686 |
0.577 |
|
2020 |
Wang B, Xu M, Li M, Wu F, Hu S, Chen X, Zhao L, Huang Z, Lan F, Liu D, Wang Y. miR-25 Promotes Cardiomyocyte Proliferation by Targeting FBXW7. Molecular Therapy. Nucleic Acids. 19: 1299-1308. PMID 32160702 DOI: 10.1016/j.omtn.2020.01.013 |
0.678 |
|
2019 |
Xie Y, Wang Q, Gao N, Wu F, Lan F, Zhang F, Jin L, Huang Z, Ge J, Wang H, Wang Y. MircroRNA-10b Promotes Human Embryonic Stem Cell-Derived Cardiomyocyte Proliferation via Novel Target Gene LATS1. Molecular Therapy. Nucleic Acids. 19: 437-445. PMID 31902743 DOI: 10.1016/J.Omtn.2019.11.026 |
0.573 |
|
2019 |
Wang D, Zhang C, Wang B, Li B, Wang Q, Liu D, Wang H, Zhou Y, Shi L, Lan F, Wang Y. Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning. Nature Communications. 10: 4284. PMID 31537810 DOI: 10.1038/s41467-019-12281-8 |
0.52 |
|
2019 |
Li X, Lu WJ, Li Y, Wu F, Bai R, Ma S, Dong T, Zhang H, Lee AS, Wang Y, Lan F. MLP-deficient human pluripotent stem cell derived cardiomyocytes develop hypertrophic cardiomyopathy and heart failure phenotypes due to abnormal calcium handling. Cell Death & Disease. 10: 610. PMID 31406109 DOI: 10.1038/s41419-019-1826-4 |
0.631 |
|
2019 |
Xu F, Yang J, Shang J, Lan F, Li M, Shi L, Shen L, Wang Y, Ge J. MicroRNA-302d promotes the proliferation of human pluripotent stem cell-derived cardiomyocytes by inhibiting in the Hippo pathway. Clinical Science (London, England : 1979). PMID 31239293 DOI: 10.1042/CS20190099 |
0.589 |
|
2019 |
Fang X, Miao S, Yu Y, Ding F, Han X, Wu H, Zhao ZA, Wang Y, Hu S, Lei W. MIR148A family regulates cardiomyocyte differentiation of human embryonic stem cells by inhibiting the DLL1-mediated NOTCH signaling pathway. Journal of Molecular and Cellular Cardiology. PMID 31233755 DOI: 10.1016/j.yjmcc.2019.06.014 |
0.598 |
|
2019 |
Wang B, Wang Z, Wang D, Zhang B, Ong SG, Li M, Yu W, Wang Y. krCRISPR: an easy and efficient strategy for generating conditional knockout of essential genes in cells. Journal of Biological Engineering. 13: 35. PMID 31049076 DOI: 10.1186/s13036-019-0150-y |
0.595 |
|
2019 |
Xie Y, Ma A, Wang B, Peng R, Jing Y, Wang D, Finnell RH, Qiao B, Wang Y, Wang H, Zheng Y. Rare mutations of from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling. Clinical Science (London, England : 1979). PMID 30610007 DOI: 10.1042/Cs20180842 |
0.316 |
|
2019 |
Miao S, Fang X, Yu Y, Han X, Wu H, Zhao Z, Wang Y, Lei W, Hu S. Abstract 408:
Mir148a
Family Regulates Cardiac Differentiation of Human Embryonic Stem Cells by Inhibiting The
Dll1
-mediated Notch Signaling Pathway Circulation Research. 125. DOI: 10.1161/res.125.suppl_1.408 |
0.384 |
|
2018 |
Xie Y, Wang D, Lan F, Wei G, Ni T, Chai R, Liu D, Hu S, Li M, Li D, Wang H, Wang Y. Author Correction: An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells. Scientific Reports. 8: 17900. PMID 30538257 DOI: 10.1038/S41598-018-36738-W |
0.683 |
|
2017 |
Xie Y, Wang D, Lan F, Wei G, Ni T, Chai R, Liu D, Hu S, Li M, Li D, Wang H, Wang Y. An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells. Scientific Reports. 7: 2320. PMID 28539611 DOI: 10.1038/S41598-017-02456-Y |
0.719 |
|
2014 |
Wang Y, Liang P, Lan F, Wu H, Lisowski L, Gu M, Hu S, Kay MA, Urnov FD, Shinnawi R, Gold JD, Gepstein L, Wu JC. Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing. Journal of the American College of Cardiology. 64: 451-9. PMID 25082577 DOI: 10.1016/J.Jacc.2014.04.057 |
0.745 |
|
2013 |
Liang P, Lan F, Lee AS, Gong T, Sanchez-Freire V, Wang Y, Diecke S, Sallam K, Knowles JW, Wang PJ, Nguyen PK, Bers DM, Robbins RC, Wu JC. Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. Circulation. 127: 1677-91. PMID 23519760 DOI: 10.1161/Circulationaha.113.001883 |
0.765 |
|
2013 |
Lan F, Lee AS, Liang P, Sanchez-Freire V, Nguyen PK, Wang L, Han L, Yen M, Wang Y, Sun N, Abilez OJ, Hu S, Ebert AD, Navarrete EG, Simmons CS, et al. Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. Cell Stem Cell. 12: 101-13. PMID 23290139 DOI: 10.1016/J.Stem.2012.10.010 |
0.708 |
|
2013 |
Hu S, Wilson KD, Ghosh Z, Han L, Wang Y, Lan F, Ransohoff KJ, Burridge P, Wu JC. MicroRNA-302 increases reprogramming efficiency via repression of NR2F2. Stem Cells (Dayton, Ohio). 31: 259-68. PMID 23136034 DOI: 10.1002/Stem.1278 |
0.725 |
|
2012 |
Wang Y, Zhang WY, Hu S, Lan F, Lee AS, Huber B, Lisowski L, Liang P, Huang M, de Almeida PE, Won JH, Sun N, Robbins RC, Kay MA, Urnov FD, et al. Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging. Circulation Research. 111: 1494-503. PMID 22967807 DOI: 10.1161/Circresaha.112.274969 |
0.775 |
|
2011 |
Nguyen PK, Lan F, Wang Y, Wu JC. Imaging: guiding the clinical translation of cardiac stem cell therapy. Circulation Research. 109: 962-79. PMID 21960727 DOI: 10.1161/Circresaha.111.242909 |
0.714 |
|
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