Manfred Zimmermann - Publications

Affiliations: 
Ruprecht-Karls-Universität Heidelberg, Heidelberg, Baden-Württemberg, Germany 

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Aira Z, Buesa I, García Del Caño G, Bilbao J, Doñate F, Zimmermann M, Azkue JJ. Transient, 5-HT2B receptor-mediated facilitation in neuropathic pain: Up-regulation of PKCγ and engagement of the NMDA receptor in dorsal horn neurons. Pain. 154: 1865-1877. PMID 23769718 DOI: 10.1016/j.pain.2013.06.009  0.334
2010 Aira Z, Buesa I, Salgueiro M, Bilbao J, Aguilera L, Zimmermann M, Azkue JJ. Subtype-specific changes in 5-HT receptor-mediated modulation of C fibre-evoked spinal field potentials are triggered by peripheral nerve injury. Neuroscience. 168: 831-41. PMID 20412834 DOI: 10.1016/j.neuroscience.2010.04.032  0.343
2008 Lu Y, Zheng J, Xiong L, Zimmermann M, Yang J. Spinal cord injury-induced attenuation of GABAergic inhibition in spinal dorsal horn circuits is associated with down-regulation of the chloride transporter KCC2 in rat. The Journal of Physiology. 586: 5701-15. PMID 18845615 DOI: 10.1113/jphysiol.2008.152348  0.377
2008 Buesa I, Urrutia A, Aira Z, Salgueiro M, Bilbao J, Mozas M, Aguilera L, Zimmermann M, Azkue JJ. Depression of C fibre-evoked spinal field potentials by the spinal delta opioid receptor is enhanced in the spinal nerve ligation model of neuropathic pain: involvement of the mu-subtype. Neuropharmacology. 55: 1376-82. PMID 18775732 DOI: 10.1016/j.neuropharm.2008.08.029  0.418
2008 Buesa I, Urrutia A, Bilbao J, Aguilera L, Zimmermann M, Azkue JJ. Morphine-induced depression of spinal excitation is not altered following acute disruption of GABA(A) or GABA(B) receptor activity. European Journal of Pain (London, England). 12: 677-85. PMID 18551744 DOI: 10.1016/j.ejpain.2007.10.011  0.411
2008 Buesa I, Urrutia A, Bilbao J, Aguilera L, Zimmermann M, Azkue JJ. Non-linear morphine-induced depression of spinal excitation following long-term potentiation of C fibre-evoked spinal field potentials. European Journal of Pain (London, England). 12: 814-7. PMID 18180186 DOI: 10.1016/j.ejpain.2007.10.016  0.443
2003 Azkue JJ, Liu XG, Zimmermann M, Sandkühler J. Induction of long-term potentiation of C fibre-evoked spinal field potentials requires recruitment of group I, but not group II/III metabotropic glutamate receptors. Pain. 106: 373-9. PMID 14659520 DOI: 10.1016/J.Pain.2003.08.007  0.35
1998 Liu XG, Morton CR, Azkue JJ, Zimmermann M, Sandkühler J. Long-term depression of C-fibre-evoked spinal field potentials by stimulation of primary afferent A delta-fibres in the adult rat. The European Journal of Neuroscience. 10: 3069-75. PMID 9786201 DOI: 10.1046/J.1460-9568.1998.00310.X  0.416
1998 Azkue JJ, Zimmermann M, Hsieh TF, Herdegen T. Peripheral nerve insult induces NMDA receptor-mediated, delayed degeneration in spinal neurons. The European Journal of Neuroscience. 10: 2204-6. PMID 9753107 DOI: 10.1046/j.1460-9568.1998.00260.x  0.45
1998 Buschmann T, Martin-Villalba A, Kocsis JD, Waxman SG, Zimmermann M, Herdegen T. Expression of Jun, Fos, and ATF-2 proteins in axotomized explanted and cultured adult rat dorsal root ganglia. Neuroscience. 84: 163-76. PMID 9522371 DOI: 10.1016/S0306-4522(97)00487-9  0.304
1997 Brecht S, Buschmann T, Grimm S, Zimmermann M, Herdegen T. Persisting expression of galanin in axotomized mamillary and septal neurons of adult rats labeled for c-Jun and NADPH-diaphorase. Brain Research. Molecular Brain Research. 48: 7-16. PMID 9379852 DOI: 10.1016/S0169-328X(97)00070-3  0.315
1997 Herdegen T, Blume A, Buschmann T, Georgakopoulos E, Winter C, Schmid W, Hsieh TF, Zimmermann M, Gass P. Expression of activating transcription factor-2, serum response factor and camp/ca response element binding protein in the adult rat brain following generalized seizures, nerve fibre lesion and ultraviolet irradiation Neuroscience. 81: 199-212. PMID 9300412 DOI: 10.1016/S0306-4522(97)00170-X  0.344
1997 Morton CR, Siegel J, Xiao HM, Zimmermann M. Modulation of cutaneous nociceptor activity by electrical stimulation in the brain stem does not inhibit the nociceptive excitation of dorsal horn neurons Pain. 71: 65-70. PMID 9200175 DOI: 10.1016/S0304-3959(97)03340-X  0.468
1997 Gillardon F, Vogel J, Hein S, Zimmermann M, Uhlmann E. Inhibition of carrageenan-induced spinal c-Fos activation by systemically administered c-fos antisense oligodeoxynucleotides may be facilitated by local opening of the blood-spinal cord barrier. Journal of Neuroscience Research. 47: 582-9. PMID 9089206 DOI: 10.1002/(SICI)1097-4547(19970315)47:6<582::AID-JNR3>3.0.CO;2-9  0.446
1997 Gillardon F, Klimaschewski L, Wickert H, Krajewski S, Reed JC, Zimmermann M. Expression pattern of candidate cell death effector proteins Bax, Bcl-2, Bcl-X, and c-Jun in sensory and motor neurons following sciatic nerve transection in the rat. Brain Research. 739: 244-50. PMID 8955944 DOI: 10.1016/S0006-8993(96)00829-3  0.3
1994 Tölle TR, Herdegen T, Schadrack J, Bravo R, Zimmermann M, Zieglgänsberger W. Application of morphine prior to noxious stimulation differentially modulates expression of Fos, Jun and Krox-24 proteins in rat spinal cord neurons. Neuroscience. 58: 305-21. PMID 8152542 DOI: 10.1016/0306-4522(94)90037-X  0.544
1994 Gillardon F, Beck H, Uhlmann E, Herdegen T, Sandkühler J, Peyman A, Zimmermann M. Inhibition of c-Fos protein expression in rat spinal cord by antisense oligodeoxynucleotide superfusion. The European Journal of Neuroscience. 6: 880-4. PMID 8075829 DOI: 10.1111/J.1460-9568.1994.Tb00999.X  0.467
1994 Herdegen T, Rüdiger S, Mayer B, Bravo R, Zimmermann M. Expression of nitric oxide synthase and colocalisation with Jun, Fos and Krox transcription factors in spinal cord neurons following noxious stimulation of the rat hindpaw. Brain Research. Molecular Brain Research. 22: 245-58. PMID 7516994 DOI: 10.1016/0169-328X(94)90053-1  0.426
1993 Herdegen T, Fiallos-Estrada CE, Bravo R, Zimmermann M. Colocalisation and covariation of c-JUN transcription factor with galanin in primary afferent neurons and with CGRP in spinal motoneurons following transection of rat sciatic nerve. Brain Research. Molecular Brain Research. 17: 147-54. PMID 7679463 DOI: 10.1016/0169-328X(93)90083-2  0.362
1992 Herdegen T, Tölle TR, Bravo R, Zieglgänsberger W, Zimmermann M. Sequential expression of JUN B, JUN D and FOS B proteins in rat spinal neurons: cascade of transcriptional operations during nociception. Neuroscience Letters. 129: 221-4. PMID 1745403 DOI: 10.1016/0304-3940(91)90466-7  0.331
1992 Leah JD, Sandkuhler J, Herdegen T, Murashov A, Zimmermann M. Potentiated expression of FOS protein in the rat spinal cord following bilateral noxious cutaneous stimulation. Neuroscience. 48: 525-32. PMID 1603331 DOI: 10.1016/0306-4522(92)90399-M  0.403
1992 Gillardon F, Wiesner RJ, Zimmermann M. Expression of the junD proto-oncogene in the rat spinal cord and skin following noxious cutaneous ultraviolet irradiation. Neuroscience Letters. 136: 87-90. PMID 1489400 DOI: 10.1016/0304-3940(92)90654-P  0.441
1992 Herdegen T, Fiallos-Estrada C, Schmid W, Bravo R, Zimmermann M. The transcription factor CREB, but not immediate-early gene encoded proteins, is expressed in activated microglia of lumbar spinal cord following sciatic nerve transection in the rat. Neuroscience Letters. 142: 57-61. PMID 1407719 DOI: 10.1016/0304-3940(92)90619-I  0.323
1992 Herdegen T, Fiallos-Estrada CE, Schmid W, Bravo R, Zimmermann M. The transcription factors c-JUN, JUN D and CREB, but not FOS and KROX-24, are differentially regulated in axotomized neurons following transection of rat sciatic nerve. Brain Research. Molecular Brain Research. 14: 155-65. PMID 1331648 DOI: 10.1016/0169-328X(92)90170-G  0.334
1991 Herdegen T, Walker T, Leah JD, Bravo R, Zimmermann M. The KROX-24 protein, a new transcription regulating factor: expression in the rat central nervous system following afferent somatosensory stimulation. Neuroscience Letters. 120: 21-4. PMID 2293086 DOI: 10.1016/0304-3940(90)90158-6  0.398
1991 Herdegen T, Leah JD, Manisali A, Bravo R, Zimmermann M. c-JUN-like immunoreactivity in the CNS of the adult rat: basal and transynaptically induced expression of an immediate-early gene. Neuroscience. 41: 643-54. PMID 1908067 DOI: 10.1016/0306-4522(91)90356-S  0.441
1991 Gillardon F, Morano I, Zimmermann M. Time course of altered levels of calcitonin gene-related peptide in rat spinal cord following skin ultraviolet irradiation Regulatory Peptides. 34: 107. DOI: 10.1016/0167-0115(91)90429-K  0.321
1990 Fu QG, Sandkühler J, Zimmermann M. B-vitamins enhance afferent inhibitory controls of nociceptive neurons in the rat spinal cord. Klinische Wochenschrift. 68: 125-8. PMID 2319731 DOI: 10.1007/Bf01646860  0.547
1990 Carstens E, Hartung M, Stelzer B, Zimmermann M. Suppression of a hind limb flexion withdrawal reflex by microinjection of glutamate or morphine into the periaqueductal gray in the rat Pain. 43: 105-112. PMID 1980535 DOI: 10.1016/0304-3959(90)90055-I  0.513
1990 Jurna I, Carlson KH, Bonke D, Fu QG, Zimmermann M. Suppression of thalamic and spinal nociceptive neuronal response by pyridoxine, thiamine, and cyanocobalamin Annals of the New York Academy of Sciences. 585: 492-495. DOI: 10.1111/j.1749-6632.1990.tb28085.x  0.487
1990 Zimmermann M, Sandkühler J, Stelzer B, Fu Q-. Spinal substance P or somatostatin superfusions fail to induce diffuse noxious inhibitory control Pain. 41. DOI: 10.1016/0304-3959(90)92587-G  0.321
1988 Fu QG, Carstens E, Stelzer B, Zimmermann M. B vitamins suppress spinal dorsal horn nociceptive neurons in the cat Neuroscience Letters. 95: 192-197. PMID 3226608 DOI: 10.1016/0304-3940(88)90655-6  0.429
1988 Sandkühler J, Zimmermann M. Neuronal effects of controlled superfusion of the spinal cord with monoaminergic receptor antagonists in the cat. Progress in Brain Research. 77: 321-7. PMID 3217533 DOI: 10.1016/S0079-6123(08)62798-3  0.563
1988 Carstens E, Stelzer B, Zimmermann M. Microinjections of glutamate or morphine at coincident midbrain sites have different effects on nociceptive dorsal horn neurons in the rat Neuroscience Letters. 95: 185-191. PMID 2906415 DOI: 10.1016/0304-3940(88)90654-4  0.5
1988 Sandkühler J, Helmchen C, Fu QG, Zimmermann M. Inhibition of spinal nociceptive neurons by excitation of cell bodies or fibers of passage at various brainstem sites in the cat. Neuroscience Letters. 93: 67-72. PMID 2905438 DOI: 10.1016/0304-3940(88)90014-6  0.514
1988 Morton CR, Du HJ, Xiao HM, Maisch B, Zimmermann M. Inhibition of nociceptive responses of lumbar dorsal horn neurones by remote noxious afferent stimulation in the cat. Pain. 34: 75-83. PMID 2841635 DOI: 10.1016/0304-3959(88)90184-4  0.463
1987 Sandkühler J, Maisch B, Zimmermann M. The use of local anaesthetic microinjections to identify central pathways: a quantitative evaluation of the time course and extent of the neuronal block. Experimental Brain Research. 68: 168-78. PMID 3691692 DOI: 10.1007/Bf00255242  0.464
1987 Sandkühler J, Fu QG, Zimmermann M. Spinal pathways mediating tonic or stimulation-produced descending inhibition from the periaqueductal gray or nucleus raphe magnus are separate in the cat. Journal of Neurophysiology. 58: 327-41. PMID 3655871 DOI: 10.1152/Jn.1987.58.2.327  0.58
1987 Carstens E, Gilly H, Schreiber H, Zimmermann M. Effects of midbrain stimulation and iontophoretic application of serotonin, noradrenaline, morphine and gaba on electrical thresholds of afferent C- and A-fibre terminals in cat spinal cord Neuroscience. 21: 395-406. PMID 3614639 DOI: 10.1016/0306-4522(87)90130-8  0.374
1987 Morton CR, Maisch B, Zimmermann M. Diffuse noxious inhibitory controls of lumbar spinal neurons involve a supraspinal loop in the cat. Brain Research. 410: 347-52. PMID 3594244 DOI: 10.1016/0006-8993(87)90336-2  0.521
1987 Sandkühler J, Maisch B, Zimmermann M. Raphe magnus-induced descending inhibition of spinal nociceptive neurons is mediated through contralateral spinal pathways in the cat. Neuroscience Letters. 76: 168-72. PMID 3587751 DOI: 10.1016/0304-3940(87)90710-5  0.6
1987 Sandkühler J, Fu QG, Helmchen C, Zimmermann M. Pentobarbital, in subanesthetic doses, depresses spinal transmission of nociceptive information but does not affect stimulation-produced descending inhibition in the cat. Pain. 31: 381-90. PMID 2827089 DOI: 10.1016/0304-3959(87)90166-7  0.557
1987 Fu Q-, Sandkuhler J, Helmchen C, Zimmermann M. Spinal superfusion with morphine affects transmission of noxious and nonnoxious information in the cat spinal dorsal horn Pain. 30. DOI: 10.1016/0304-3959(87)91848-3  0.459
1987 Sandkühler J, Fu Q-, Helmchen C, Zimmermann M. Spinal neurotransmitters and funicular trajectories mediating descending inhibition of nociceptive dorsal horn neurons in the cat Pain. 30. DOI: 10.1016/0304-3959(87)91300-5  0.521
1986 Dickhaus H, Pauser G, Zimmermann M. Tonic descending inhibition affects intensity coding of nociceptive responses of spinal dorsal horn neurones in the cat. Pain. 23: 145-158. PMID 4069718 DOI: 10.1016/0304-3959(85)90056-9  0.577
1986 Siegel J, Morton CR, Sandkühler J, Xiao HM, Zimmermann M. Spinal neuronal inhibition and EEG synchrony by electrical stimulation in subcortical forebrain regions of the cat. Experimental Brain Research. 62: 363-72. PMID 3709719 DOI: 10.1007/Bf00238856  0.512
1986 Morton CR, Maisch B, Zimmermann M. Calcitonin: brainstem microinjection but not systemic administration inhibits spinal nociceptive transmission in the cat. Brain Research. 372: 149-54. PMID 3708352 DOI: 10.1016/0006-8993(86)91468-X  0.545
1985 Gebhart GF, Sandkühler J, Thalhammer JG, Zimmermann M. Inhibition in spinal cord of nociceptive information by electrical stimulation and morphine microinjection at identical sites in midbrain of the cat Pain. 22: 206. DOI: 10.1016/0304-3959(85)90185-X  0.576
1984 Gebhart GF, Sandkühler J, Thalhammer JG, Zimmermann M. Inhibition in spinal cord of nociceptive information by electrical stimulation and morphine microinjection at identical sites in midbrain of the cat. Journal of Neurophysiology. 51: 75-89. PMID 6693935 DOI: 10.1016/0304-3959(85)90185-X  0.614
1984 Gmelin G, Zimmermann M. Effects of gamma-aminobutyrate and bicuculline on primary afferent depolarization of cutaneous fibres in the cat spinal cord. Neuroscience. 10: 869-74. PMID 6646432 DOI: 10.1016/0306-4522(83)90224-5  0.416
1984 Du HJ, Kitahata LM, Thalhammer JG, Zimmermann M. Inhibition of nociceptive neuronal responses in the cat's spinal dorsal horn by electrical stimulation and morphine microinjection in nucleus raphe magnus. Pain. 19: 249-257. PMID 6472873 DOI: 10.1016/0304-3959(84)90003-4  0.563
1983 Brinkhus HB, Zimmermann M. Characteristics of spinal dorsal horn neurons after partial chronic deafferentation by dorsal root transection. Pain. 15: 221-36. PMID 6856322 DOI: 10.1016/0304-3959(83)90058-1  0.482
1983 Gebhart GF, Sandkühler J, Thalhammer JG, Zimmermann M. Inhibition of spinal nociceptive information by stimulation in midbrain of the cat is blocked by lidocaine microinjected in nucleus raphe magnus and medullary reticular formation. Journal of Neurophysiology. 50: 1446-59. PMID 6663337 DOI: 10.1152/Jn.1983.50.6.1446  0.63
1983 Gebhart GF, Sandkühler J, Thalhammer JG, Zimmermann M. Quantitative comparison of inhibition in spinal cord of nociceptive information by stimulation in periaqueductal gray or nucleus raphe magnus of the cat. Journal of Neurophysiology. 50: 1433-45. PMID 6663336 DOI: 10.1152/Jn.1983.50.6.1433  0.639
1982 Randić M, Carstens E, Zimmermann M, Klumpp D. Dual effects of substance P on the excitability of single cutaneous primary afferent C- and A-fibers in the cat spinal cord. Brain Research. 233: 389-93. PMID 6174179  0.426
1982 Thalhammer JG, Gebhart GF, Sandkühler J, Zimmermann M. Inhibition of spinal neurons by microinjection of morphine and focal stimulation in the mesencephalon of the cat PflüGers Archiv European Journal of Physiology. 394: R59-R59. DOI: 10.1007/Bf02580812  0.593
1981 Carstens E, Klumpp D, Randić M, Zimmermann M. Effect of iontophoretically applied 5-hydroxytryptamine on the excitability of single primary afferent C- and A-fibers in the cat spinal cord. Brain Research. 220: 151-8. PMID 7272748 DOI: 10.1016/0006-8993(81)90218-3  0.318
1981 Carstens E, Fraunhoffer M, Zimmermann M. Serotonergic mediation of descending inhibition from midbrain periaqueductal gray, but not reticular formation, of spinal nociceptive transmission in the cat Pain. 10: 149-167. PMID 6267541 DOI: 10.1016/0304-3959(81)90191-3  0.491
1981 Carstens E, Bihl H, Irvine DR, Zimmermann M. Descending inhibition from medial and lateral midbrain of spinal dorsal horn neuronal responses to noxious and nonnoxious cutaneous stimuli in the cat. Journal of Neurophysiology. 45: 1029-42. PMID 6265605 DOI: 10.1152/Jn.1981.45.6.1029  0.535
1980 Carstens E, Zimmermann M. The opiate antagonist naloxone does not consistently block inhibition of spinal nociceptive transmission produced by stimulation in lateral midbrain reticular formation of the cat Neuroscience Letters. 20: 335-339. PMID 7443080 DOI: 10.1016/0304-3940(80)90170-6  0.585
1980 Carstens E, Klumpp D, Zimmermann M. Differential inhibitory effects of medial and lateral midbrain stimulatiom on spinal neuronal discharges to noxious skin heating in the cat Journal of Neurophysiology. 43: 332-342. PMID 7381524 DOI: 10.1152/Jn.1980.43.2.332  0.568
1980 Carstens E, Klumpp D, Zimmermann M. Time course and effective sites for inhibition from midbrain periaqueductal gray of spinal dorsal horn neuronal responses to cutaneous stimuli in the cat Experimental Brain Research. 38: 425-430. PMID 7363975 DOI: 10.1007/Bf00237522  0.626
1979 Brinkhus HB, Carstens E, Zimmermann M. Encoding of graded noxious skin heating by neurons in posterior thalamus and adjacent areas in the cat Neuroscience Letters. 15: 37-42. PMID 530514 DOI: 10.1016/0304-3940(79)91526-X  0.334
1979 Carstens E, Yokota T, Zimmermann M. Inhibition of spinal neuronal responses of noxious skin heating by stimulation of mesencephalic periaqueductal gray in the cat Journal of Neurophysiology. 42: 558-568. PMID 422977 DOI: 10.1152/Jn.1979.42.2.558  0.516
1979 Carstens E, Klumpp D, Zimmermann M. The opiate antagonist, naloxone, does not affect descending inhibition from midbrain of nociceptive spinal neuronal discharges in the cat Neuroscience Letters. 11: 323-327. PMID 229438 DOI: 10.1016/0304-3940(79)90016-8  0.575
1978 Aitkin LM, Dickhaus H, Schult W, Zimmermann M. External nucleus of inferior colliculus: auditory and spinal somatosensory afferents and their interactions. Journal of Neurophysiology. 41: 837-47. PMID 681989  0.401
1976 Beck PW, Handwerker HO, Zimmermann M. Nervous outflow from the cat's foot during noxious radiant heat stimulation. Brain Research. 67: 373-86. PMID 4470431 DOI: 10.1016/0006-8993(74)90488-0  0.344
1976 Beck PW, Handwerker HO, Zimmermann M. Physiology Nervous outflow from the catʼs foot during noxious radiant heat stimulation Pain. 2: 439. DOI: 10.1016/0304-3959(76)90086-5  0.352
1975 Handwerker HO, Iggo A, Zimmermann M. Segmental and supraspinal actions on dorsal horn neurons responding to noxious and non-noxious skin stimuli. Pain. 1: 147-65. PMID 1235979 DOI: 10.1016/0304-3959(75)90099-8  0.354
1972 Gregor M, Zimmermann M. Characteristics of spinal neurones responding to cutaneous myelinated and unmyelinated fibres. The Journal of Physiology. 221: 555-76. PMID 5016361 DOI: 10.1113/jphysiol.1972.sp009767  0.454
1972 Handwerker HO, Zimmermann M. Cortical evoked responses upon selective stimulations of cutaneous group 3 fibers and the mediating spinal pathways. Brain Research. 36: 437-40. PMID 5009651 DOI: 10.1016/0006-8993(72)90751-2  0.413
1968 Jänig W, Schmidt RF, Zimmermann M. Single unit responses and the total afferent outflow from the cat's foot pad upon mechanical stimulation. Experimental Brain Research. 6: 100-15. PMID 5721757  0.337
1968 Zimmermann M. Dorsal root potentials after C-fiber stimulation. Science (New York, N.Y.). 160: 896-8. PMID 5239306 DOI: 10.1126/science.160.3830.896  0.38
1967 Schmidt RF, Senges J, Zimmermann M. Presynaptic depolarization of cutaneous mechanoreceptor afferents after mechanical skin stimulation. Experimental Brain Research. 3: 234-47. PMID 6030824 DOI: 10.1007/BF00235587  0.305
1967 Schmidt RF, Trautwein W, Zimmermann M. Dorsal root potentials evoked by natural stimulation of cutaneous afferents. Nature. 212: 522-3. PMID 5970194 DOI: 10.1038/212522A0  0.423
1967 Braun M, Schmidt RF, Zimmermann M. Facilitation at the frog neuromuscular junction during and after repetitive stimulation. Pflugers Archiv Fur Die Gesamte Physiologie Des Menschen Und Der Tiere. 287: 41-55. PMID 4293060 DOI: 10.1007/BF00362453  0.325
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