Aaron Bowman - Publications

Vanderbilt University, Nashville, TN 
Huntington's Disease

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tabbassum S, Cheng P, Yanko FM, Balachandran R, Aschner M, Bowman AB, Nie LH. Whole body potassium as a biomarker for potassium uptake using a mouse model. Scientific Reports. 11: 6385. PMID 33737537 DOI: 10.1038/s41598-021-85233-2  0.4
2021 Horning KJ, Tang X, Thomas MG, Aschner M, Bowman AB. Identification of Three Small Molecules That Can Selectively Influence Cellular Manganese Levels in a Mouse Striatal Cell Model. Molecules (Basel, Switzerland). 26. PMID 33671818 DOI: 10.3390/molecules26041175  0.4
2021 Morcillo P, Cordero H, Ijomone OM, Ayodele A, Bornhorst J, Gunther L, Macaluso FP, Bowman AB, Aschner M. Defective Mitochondrial Dynamics Underlie Manganese-Induced Neurotoxicity. Molecular Neurobiology. PMID 33666854 DOI: 10.1007/s12035-021-02341-w  0.4
2021 Ke T, Prince LM, Bowman AB, Aschner M. Latent alterations in swimming behavior by developmental methylmercury exposure are modulated by the homolog of tyrosine hydroxylase in Caenorhabditis elegans. Neurotoxicology and Teratology. 106963. PMID 33626374 DOI: 10.1016/j.ntt.2021.106963  0.4
2021 Martins AC, Ruella Oliveira S, Barbosa F, Tinkov AA, V A, Santamaría A, Lee E, Bowman AB, Aschner M. Evaluating the risk of manganese-induced neurotoxicity of parenteral nutrition: review of the current literature. Expert Opinion On Drug Metabolism & Toxicology. PMID 33620266 DOI: 10.1080/17425255.2021.1894123  0.4
2020 Aschner M, Paoliello MMB, Tsatsakis A, Bowman AB, Dorea JG, Hartung T, Domingo JL, Barbosa F. Social injustice in environmental health: A call for fortitude. Environmental Research. 194: 110675. PMID 33373610 DOI: 10.1016/j.envres.2020.110675  0.4
2020 Ferrer B, Prince LM, Tinkov AA, Santamaria A, Farina M, Rocha JB, Bowman AB, Aschner M. Chronic Exposure to Methylmercury Enhances the Anorexigenic Effects of Leptin in C57BL/6J Male Mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 111924. PMID 33338554 DOI: 10.1016/j.fct.2020.111924  0.4
2020 Ferrer B, Prince LM, Tinkov AA, Santamaria A, Bowman AB, Aschner M. Chronic exposure to methylmercury disrupts ghrelin actions in C57BL/6J mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 147: 111918. PMID 33301842 DOI: 10.1016/j.fct.2020.111918  0.4
2020 Chen P, Bornhorst J, Patton S, Bagai K, Nitin R, Miah M, Hare DJ, Kysenius K, Crouch PJ, Xiong L, Rouleau GA, Schwerdtle T, Connor J, Aschner M, Bowman AB, et al. A potential role for Zinc in Restless Legs Syndrome. Sleep. PMID 33175142 DOI: 10.1093/sleep/zsaa236  0.4
2020 Ke T, Santamaria A, Rocha JBT, Tinkov A, Bornhorst J, Bowman AB, Aschner M. Cephalic Neuronal Vesicle Formation is Developmentally Dependent and Modified by Methylmercury and sti-1 in Caenorhabditis elegans. Neurochemical Research. PMID 33037975 DOI: 10.1007/s11064-020-03142-8  0.4
2020 Martins AC, Gubert P, Villas Boas GR, Meirelles Paes M, Santamaría A, Lee E, Tinkov AA, Bowman AB, Aschner M. Manganese Induced neurodegenerative diseases and possible therapeutic approaches. Expert Review of Neurotherapeutics. PMID 32799578 DOI: 10.1080/14737175.2020.1807330  0.4
2020 Ke T, Antunes Soares FA, Santamaría A, Bowman AB, Skalny AV, Aschner M. N,N' bis-(2-mercaptoethyl) isophthalamide induces developmental delay in by promoting DAF-16 nuclear localization. Toxicology Reports. 7: 930-937. PMID 32793422 DOI: 10.1016/j.toxrep.2020.07.012  0.4
2020 Ke T, Santamaria A, Rocha JBT, Tinkov AA, Lu R, Bowman AB, Aschner M. The Role of Human LRRK2 in Methylmercury-Induced Inhibition of Microvesicle Formation of Cephalic Neurons in Caenorhabditis elegans. Neurotoxicity Research. PMID 32725544 DOI: 10.1007/s12640-020-00262-5  0.4
2020 Warren EB, Bryan MR, Morcillo P, Hardeman KN, Aschner M, Bowman AB. Manganese-induced mitochondrial dysfunction is not detectable at exposures below the acute cytotoxic threshold in neuronal cell types. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 32492146 DOI: 10.1093/toxsci/kfaa079  0.56
2020 Soares ATG, Silva AC, Tinkov AA, Khan H, Santamaría A, Skalnaya MG, Skalny AV, Tsatsakis A, Bowman AB, Aschner M, Ávila DS. The impact of manganese on neurotransmitter systems. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 61: 126554. PMID 32480053 DOI: 10.1016/j.jtemb.2020.126554  0.4
2020 Cunha Martins A, Krum BN, Queirós LSS, Tinkov AA, Skalny AV, Bowman AB, Aschner M. Manganese in diet: bioaccessibility, adequate intake and neurotoxicological effects. Journal of Agricultural and Food Chemistry. PMID 32298096 DOI: 10.1021/acs.jafc.0c00641  0.4
2020 Ke T, Bornhorst J, Schwerdtle T, Santamaría A, Soare FAA, Rocha JBT, Farina M, Bowman AB, Aschner M. Therapeutic Efficacy of the N,N' Bis-(2-Mercaptoethyl) Isophthalamide Chelator for Methylmercury Intoxication in Caenorhabditis elegans. Neurotoxicity Research. PMID 32236898 DOI: 10.1007/s12640-020-00194-0  0.4
2020 Balachandran RC, Mukhopadhyay S, McBride D, Veevers J, Harrison FE, Aschner M, Haynes EN, Bowman AB. Brain Manganese and the Balance between Essential Roles and Neurotoxicity. The Journal of Biological Chemistry. PMID 32188696 DOI: 10.1074/jbc.REV119.009453  0.4
2020 Horning KJ, Joshi P, Nitin R, Balachandran RC, Yanko FM, Kim K, Christov P, Aschner M, Sulikowski GA, Weaver CD, Bowman AB. Identification of a selective manganese ionophore that enables non-lethal quantification of cellular manganese. The Journal of Biological Chemistry. PMID 32047113 DOI: 10.1074/jbc.RA119.009781  0.4
2020 Miah MR, Ijomone OM, Okoh COA, Ijomone OK, Akingbade GT, Ke T, Krum B, da Cunha Martins A, Akinyemi A, Aranoff N, Antunes Soares FA, Bowman AB, Aschner M. The effects of manganese overexposure on brain health. Neurochemistry International. 104688. PMID 31972215 DOI: 10.1016/j.neuint.2020.104688  0.4
2020 Ke T, Tsatsakis A, Santamaría A, Antunes Soare FA, Tinkov AA, Docea AO, Skalny A, Bowman AB, Aschner M. Chronic exposure to methylmercury induces puncta formation in cephalic dopaminergic neurons in Caenorhabditis elegans. Neurotoxicology. PMID 31935438 DOI: 10.1016/j.neuro.2020.01.003  0.4
2019 Bryan MR, Nordham KD, Rose DIR, O'Brien MT, Joshi P, Foshage AM, Gonçalves FM, Nitin R, Uhouse MA, Aschner M, Bowman AB. Manganese Acts upon Insulin/IGF Receptors to Phosphorylate AKT and Increase Glucose Uptake in Huntington's Disease Cells. Molecular Neurobiology. PMID 31797328 DOI: 10.1007/s12035-019-01824-1  0.56
2019 Zhang Z, Yan J, Bowman AB, Bryan MR, Singh R, Aschner M. Dysregulation of TFEB contributes to Manganese-induced Autophagic Failure and Mitochondrial Dysfunction in Astrocytes. Autophagy. PMID 31690173 DOI: 10.1080/15548627.2019.1688488  0.56
2019 Bryan MR, O'Brien MT, Nordham KD, Rose DIR, Foshage AM, Joshi P, Nitin R, Uhouse MA, Di Pardo A, Zhang Z, Maglione V, Aschner M, Bowman AB. Acute manganese treatment restores defective autophagic cargo loading in Huntington's Disease cell lines. Human Molecular Genetics. PMID 31600787 DOI: 10.1093/hmg/ddz209  0.56
2019 Martins AC, Morcillo P, Ijomone OM, Venkataramani V, Harrison FE, Lee E, Bowman AB, Aschner M. New Insights on the Role of Manganese in Alzheimer's Disease and Parkinson's Disease. International Journal of Environmental Research and Public Health. 16. PMID 31546716 DOI: 10.3390/ijerph16193546  0.4
2019 Ruszkiewicz JA, Tinkov AA, Skalny AV, Siokas V, Dardiotis E, Tsatsakis A, Bowman AB, da Rocha JBT, Aschner M. Brain diseases in changing climate. Environmental Research. 177: 108637. PMID 31416010 DOI: 10.1016/j.envres.2019.108637  0.4
2019 Chen P, Totten M, Zhang Z, Bucinca H, Erikson K, Santamaría A, Bowman AB, Aschner M. Iron and manganese-related CNS toxicity: mechanisms, diagnosis and treatment. Expert Review of Neurotherapeutics. PMID 30759034 DOI: 10.1080/14737175.2019.1581608  0.4
2019 Prince LM, Aschner M, Bowman AB. Human-induced pluripotent stems cells as a model to dissect the selective neurotoxicity of methylmercury. Biochimica Et Biophysica Acta. General Subjects. PMID 30742955 DOI: 10.1016/j.bbagen.2019.02.002  0.4
2018 Ke T, Gonçalves FM, Gonçalves CL, Dos Santos AA, Rocha JBT, Farina M, Skalny A, Tsatsakis A, Bowman AB, Aschner M. Post-translational modifications in MeHg-induced neurotoxicity. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30385410 DOI: 10.1016/j.bbadis.2018.10.024  0.4
2018 Schetinger MRC, Peres TV, Arantes LP, Carvalho F, Dressler V, Heidrich G, Bowman AB, Aschner M. Combined exposure to methylmercury and manganese during L1 larval stage causes motor dysfunction, cholinergic and monoaminergic up-regulation and oxidative stress in L4 Caenorhabditis elegans. Toxicology. PMID 30336192 DOI: 10.1016/j.tox.2018.10.006  0.4
2018 Peres TV, Horning KJ, Bornhorst J, Schwerdtle T, Bowman AB, Aschner M. Small Molecule Modifiers of In Vitro Manganese Transport Alter Toxicity In Vivo. Biological Trace Element Research. PMID 30267310 DOI: 10.1007/s12011-018-1531-7  0.4
2018 Ruszkiewicz JA, Teixeira de Macedo G, Miranda-Vizuete A, Bowman AB, Bornhorst J, Schwerdtle T, Antunes Soares FA, Aschner M. Sex-Specific Response of Caenorhabditis elegans to Methylmercury Toxicity. Neurotoxicity Research. PMID 30155682 DOI: 10.1007/s12640-018-9949-4  0.4
2018 Ruszkiewicz JA, Teixeira de Macedo G, Miranda-Vizuete A, Teixeira da Rocha JB, Bowman AB, Bornhorst J, Schwerdtle T, Aschner M. The cytoplasmic thioredoxin system in Caenorhabditis elegans affords protection from methylmercury in an age-specific manner. Neurotoxicology. 68: 189-202. PMID 30138651 DOI: 10.1016/j.neuro.2018.08.007  0.4
2018 Peres TV, Arantes LP, Miah MR, Bornhorst J, Schwerdtle T, Bowman AB, Leal RB, Aschner M. Role of Caenorhabditis elegans AKT-1/2 and SGK-1 in Manganese Toxicity. Neurotoxicity Research. PMID 29882004 DOI: 10.1007/s12640-018-9915-1  0.4
2018 Antunes Dos Santos A, López-Granero C, Farina M, Rocha JBT, Bowman AB, Aschner M. Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 29428217 DOI: 10.1016/j.fct.2018.01.057  0.4
2017 Bryan MR, Bowman AB. Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders. Advances in Neurobiology. 18: 113-142. PMID 28889265 DOI: 10.1007/978-3-319-60189-2_6  0.56
2017 Bryan MR, Uhouse MA, Nordham KD, Joshi P, Rose DIR, O'Brien MT, Aschner M, Bowman AB. Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell signaling in a murine striatal cell line. Neurotoxicology. PMID 28780388 DOI: 10.1016/j.neuro.2017.07.026  0.56
2017 López-Granero C, Antunes Dos Santos A, Ferrer B, Culbreth M, Chakraborty S, Barrasa A, Gulinello M, Bowman AB, Aschner M. BXD recombinant inbred strains participate in social preference, anxiety and depression behaviors along sex-differences in cytokines and tactile allodynia. Psychoneuroendocrinology. 80: 92-98. PMID 28324704 DOI: 10.1016/j.psyneuen.2017.03.006  0.4
2016 Osmand AP, Bichell TJ, Bowman AB, Bates GP. Embryonic Mutant Huntingtin Aggregate Formation in Mouse Models of Huntington's Disease. Journal of Huntington's Disease. PMID 27886014 DOI: 10.3233/JHD-160217  0.4
2016 Peres TV, Schettinger MR, Chen P, Carvalho F, Avila DS, Bowman AB, Aschner M. "Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies". Bmc Pharmacology & Toxicology. 17: 57. PMID 27814772 DOI: 10.1186/S40360-016-0099-0  0.4
2016 Ruszkiewicz JA, Bowman AB, Farina M, Rocha JB, Aschner M. Sex- and structure-specific differences in antioxidant responses to methylmercury during early development. Neurotoxicology. PMID 27456245 DOI: 10.1016/j.neuro.2016.07.009  0.4
2016 Tidball AM, Neely MD, Chamberlin R, Aboud AA, Kumar KK, Han B, Bryan MR, Aschner M, Ess KC, Bowman AB. Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem Cells. Plos One. 11: e0150372. PMID 26982737 DOI: 10.1371/Journal.Pone.0150372  0.72
2015 Brown JA, Pensabene V, Markov DA, Allwardt V, Neely MD, Shi M, Britt CM, Hoilett OS, Yang Q, Brewer BM, Samson PC, McCawley LJ, May JM, Webb DJ, Li D, ... Bowman AB, et al. Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor. Biomicrofluidics. 9: 054124. PMID 26576206 DOI: 10.1063/1.4934713  0.8
2015 Pancani T, Foster DJ, Moehle MS, Bichell TJ, Bradley E, Bridges TM, Klar R, Poslusney M, Rook JM, Daniels JS, Niswender CM, Jones CK, Wood MR, Bowman AB, Lindsley CW, et al. Allosteric activation of M4 muscarinic receptors improve behavioral and physiological alterations in early symptomatic YAC128 mice. Proceedings of the National Academy of Sciences of the United States of America. 112: 14078-83. PMID 26508634 DOI: 10.1073/Pnas.1512812112  0.8
2015 Chen P, Bowman AB, Mukhopadhyay S, Aschner M. SLC30A10: A novel manganese transporter. Worm. 4: e1042648. PMID 26430566 DOI: 10.1080/21624054.2015.1042648  0.4
2015 Parmalee NL, Maqbool SB, Ye B, Calder B, Bowman AB, Aschner M. RNASeq in C. elegans Following Manganese Exposure. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 65: 11.20.1-11.20.17. PMID 26250396 DOI: 10.1002/0471140856.tx1120s65  0.8
2015 Chun YW, Balikov DA, Feaster TK, Williams CH, Sheng CC, Lee JB, Boire TC, Neely MD, Bellan LM, Ess KC, Bowman AB, Sung HJ, Hong CC. Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes. Biomaterials. 67: 52-64. PMID 26204225 DOI: 10.1016/J.Biomaterials.2015.07.004  0.8
2015 Kwakye GF, Paoliello MM, Mukhopadhyay S, Bowman AB, Aschner M. Manganese-Induced Parkinsonism and Parkinson's Disease: Shared and Distinguishable Features. International Journal of Environmental Research and Public Health. 12: 7519-40. PMID 26154659 DOI: 10.3390/ijerph120707519  0.8
2015 Chen P, Chakraborty S, Mukhopadhyay S, Lee E, Paoliello MM, Bowman AB, Aschner M. Manganese homeostasis in the nervous system. Journal of Neurochemistry. 134: 601-10. PMID 25982296 DOI: 10.1111/Jnc.13170  0.8
2015 Horning KJ, Caito SW, Tipps KG, Bowman AB, Aschner M. Manganese Is Essential for Neuronal Health. Annual Review of Nutrition. 35: 71-108. PMID 25974698 DOI: 10.1146/annurev-nutr-071714-034419  0.8
2015 Chen P, Chakraborty S, Peres TV, Bowman AB, Aschner M. Manganese-induced Neurotoxicity: From C. elegans to Humans. Toxicology Research. 4: 191-202. PMID 25893090 DOI: 10.1039/C4Tx00127C  0.8
2015 Chakraborty S, Chen P, Bornhorst J, Schwerdtle T, Schumacher F, Kleuser B, Bowman AB, Aschner M. Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans. Metallomics : Integrated Biometal Science. 7: 847-56. PMID 25769119 DOI: 10.1039/C5Mt00052A  0.8
2015 Kumar KK, Goodwin CR, Uhouse MA, Bornhorst J, Schwerdtle T, Aschner M, McLean JA, Bowman AB. Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese status. Metallomics : Integrated Biometal Science. 7: 363-70. PMID 25599126 DOI: 10.1039/C4Mt00223G  0.8
2015 Chen P, DeWitt MR, Bornhorst J, Soares FA, Mukhopadhyay S, Bowman AB, Aschner M. Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson's disease. Metallomics : Integrated Biometal Science. 7: 289-98. PMID 25531510 DOI: 10.1039/C4Mt00292J  0.8
2015 Tidball AM, Bryan MR, Uhouse MA, Kumar KK, Aboud AA, Feist JE, Ess KC, Neely MD, Aschner M, Bowman AB. A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease. Human Molecular Genetics. 24: 1929-44. PMID 25489053 DOI: 10.1093/Hmg/Ddu609  0.8
2015 Wegrzynowicz M, Bichell TJ, Soares BD, Loth MK, McGlothan JL, Alikhan FS, Hua K, Coughlin JM, Holt HK, Jetter CS, Mori S, Pomper MG, Osmand AP, Guilarte TR, Bowman AB. Novel BAC Mouse Model of Huntington's Disease with 225 CAG Repeats Exhibits an Early Widespread and Stable Degenerative Phenotype Journal of Huntington's Disease. 4: 17-36. DOI: 10.3233/JHD-140116  0.8
2015 Bichell TJ, Uhouse M, Bradley E, Bowman AB. Gene-Environment Interactions in Huntington's Disease Environmental Factors in Neurodevelopmental and Neurodegenerative Disorders. 355-383. DOI: 10.1016/B978-0-12-800228-5.00017-0  0.8
2015 Tidball AM, Bichell TJ, Bowman AB. Manganese and huntington disease Issues in Toxicology. 2015: 540-573.  0.8
2014 Kumar KK, Lowe EW, Aboud AA, Neely MD, Redha R, Bauer JA, Odak M, Weaver CD, Meiler J, Aschner M, Bowman AB. Cellular manganese content is developmentally regulated in human dopaminergic neurons. Scientific Reports. 4: 6801. PMID 25348053 DOI: 10.1038/Srep06801  0.8
2014 Leyva-Illades D, Chen P, Zogzas CE, Hutchens S, Mercado JM, Swaim CD, Morrisett RA, Bowman AB, Aschner M, Mukhopadhyay S. SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14079-95. PMID 25319704 DOI: 10.1523/Jneurosci.2329-14.2014  0.8
2014 Aboud AA, Tidball AM, Kumar KK, Neely MD, Han B, Ess KC, Hong CC, Erikson KM, Hedera P, Bowman AB. PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper. Neurobiology of Disease. 73: 204-212. PMID 25315681 DOI: 10.1016/J.Nbd.2014.10.002  0.8
2014 Stansfield KH, Bichell TJ, Bowman AB, Guilarte TR. BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity. Journal of Neurochemistry. 131: 655-66. PMID 25099302 DOI: 10.1111/jnc.12926  0.8
2014 Bowman AB, Aschner M. Considerations on manganese (Mn) treatments for in vitro studies. Neurotoxicology. 41: 141-2. PMID 24509086 DOI: 10.1016/j.neuro.2014.01.010  0.8
2014 Bornhorst J, Chakraborty S, Meyer S, Lohren H, Brinkhaus SG, Knight AL, Caldwell KA, Caldwell GA, Karst U, Schwerdtle T, Bowman A, Aschner M. The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans. Metallomics : Integrated Biometal Science. 6: 476-90. PMID 24452053 DOI: 10.1039/c3mt00325f  0.8
2014 Bowman AB, Kwakye GF, Hernandez EH, Aschner M. The role of manganese in neurodegenerative diseases | Die Rolle von Mangan bei neurodegenerativen Erkrankungen Perspectives in Medicine. 2: 91-108. DOI: 10.1016/j.permed.2011.08.001  0.8
2013 Srinivasakumar N, Zaboikin M, Tidball AM, Aboud AA, Neely MD, Ess KC, Bowman AB, Schuening FG. Gammaretroviral vector encoding a fluorescent marker to facilitate detection of reprogrammed human fibroblasts during iPSC generation. Peerj. 1: e224. PMID 24392288 DOI: 10.7717/Peerj.224  0.8
2013 Kumar KK, Aboud AA, Patel DK, Aschner M, Bowman AB. Optimization of fluorescence assay of cellular manganese status for high throughput screening. Journal of Biochemical and Molecular Toxicology. 27: 42-9. PMID 23169769 DOI: 10.1002/Jbt.21457  0.8
2013 Bowman AB, Ess KC, Kumar KK, Summar KL. Down Syndrome Neural Circuit Development and Function in the Heathy and Diseased Brain. 547-571. DOI: 10.1016/B978-0-12-397267-5.00130-8  0.8
2012 Aboud AA, Tidball AM, Kumar KK, Neely MD, Ess KC, Erikson KM, Bowman AB. Genetic risk for Parkinson's disease correlates with alterations in neuronal manganese sensitivity between two human subjects. Neurotoxicology. 33: 1443-9. PMID 23099318 DOI: 10.1016/J.Neuro.2012.10.009  0.8
2012 Neely MD, Litt MJ, Tidball AM, Li GG, Aboud AA, Hopkins CR, Chamberlin R, Hong CC, Ess KC, Bowman AB. DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. Acs Chemical Neuroscience. 3: 482-91. PMID 22860217 DOI: 10.1021/Cn300029T  0.8
2012 Madison JL, Wegrzynowicz M, Aschner M, Bowman AB. Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism. Plos One. 7: e31024. PMID 22363539 DOI: 10.1371/journal.pone.0031024  0.8
2012 Kumar KK, Aboud AA, Bowman AB. The potential of induced pluripotent stem cells as a translational model for neurotoxicological risk. Neurotoxicology. 33: 518-29. PMID 22330734 DOI: 10.1016/J.Neuro.2012.02.005  0.8
2012 Wegrzynowicz M, Holt HK, Friedman DB, Bowman AB. Changes in the striatal proteome of YAC128Q mice exhibit gene-environment interactions between mutant huntingtin and manganese. Journal of Proteome Research. 11: 1118-32. PMID 22191580 DOI: 10.1021/pr200839d  0.8
2012 Xu L, Mirnics K, Bowman AB, Liu W, Da J, Porter NA, Korade Z. DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemli-Opitz syndrome model. Neurobiology of Disease. 45: 923-9. PMID 22182693 DOI: 10.1016/J.Nbd.2011.12.011  0.8
2011 Lee Y, Fryer JD, Kang H, Crespo-Barreto J, Bowman AB, Gao Y, Kahle JJ, Hong JS, Kheradmand F, Orr HT, Finegold MJ, Zoghbi HY. ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization. Developmental Cell. 21: 746-57. PMID 22014525 DOI: 10.1016/J.Devcel.2011.08.017  0.8
2011 Bowman AB, Kwakye GF, Herrero Hernández E, Aschner M. Role of manganese in neurodegenerative diseases. Journal of Trace Elements in Medicine and Biology : Organ of the Society For Minerals and Trace Elements (Gms). 25: 191-203. PMID 21963226 DOI: 10.1016/j.jtemb.2011.08.144  0.8
2011 Grover VK, Valadez JG, Bowman AB, Cooper MK. Lipid modifications of Sonic hedgehog ligand dictate cellular reception and signal response. Plos One. 6: e21353. PMID 21747935 DOI: 10.1371/journal.pone.0021353  0.8
2011 Madison JL, Wegrzynowicz M, Aschner M, Bowman AB. Gender and manganese exposure interactions on mouse striatal neuron morphology. Neurotoxicology. 32: 896-906. PMID 21641932 DOI: 10.1016/j.neuro.2011.05.007  0.8
2011 Kwakye GF, Li D, Kabobel OA, Bowman AB. Cellular fura-2 manganese extraction assay (CFMEA). Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit12.18. PMID 21553393 DOI: 10.1002/0471140856.tx1218s48  0.8
2011 Kwakye GF, Li D, Bowman AB. Novel high-throughput assay to assess cellular manganese levels in a striatal cell line model of Huntington's disease confirms a deficit in manganese accumulation. Neurotoxicology. 32: 630-9. PMID 21238486 DOI: 10.1016/j.neuro.2011.01.002  0.8
2011 Sidoryk-Wegrzynowicz M, Wegrzynowicz M, Lee E, Bowman AB, Aschner M. Role of astrocytes in brain function and disease. Toxicologic Pathology. 39: 115-23. PMID 21075920 DOI: 10.1177/0192623310385254  0.8
2011 Neely MD, Tidball AM, Aboud AA, Ess KC, Bowman AB. Induced pluripotent stem cells (iPSCs): An emerging model system for the study of human neurotoxicology Neuromethods. 56: 27-61. DOI: 10.1007/978-1-61779-077-5_2  0.8
2010 Williams BB, Kwakye GF, Wegrzynowicz M, Li D, Aschner M, Erikson KM, Bowman AB. Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 169-79. PMID 20547568 DOI: 10.1093/toxsci/kfq174  0.8
2010 Milatovic D, Montine TJ, Zaja-Milatovic S, Madison JL, Bowman AB, Aschner M. Morphometric analysis in neurodegenerative disorders. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit 12.16. PMID 20401325 DOI: 10.1002/0471140856.Tx1216S43  0.8
2010 Yin Z, Jiang H, Lee ES, Ni M, Erikson KM, Milatovic D, Bowman AB, Aschner M. Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation. Journal of Neurochemistry. 112: 1190-8. PMID 20002294 DOI: 10.1111/j.1471-4159.2009.06534.x  0.8
2010 Williams BB, Li D, Wegrzynowicz M, Vadodaria BK, Anderson JG, Kwakye GF, Aschner M, Erikson KM, Bowman AB. Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure. Journal of Neurochemistry. 112: 227-37. PMID 19845833 DOI: 10.1111/j.1471-4159.2009.06445.x  0.8
2009 Halladay AK, Amaral D, Aschner M, Bolivar VJ, Bowman A, DiCicco-Bloom E, Hyman SL, Keller F, Lein P, Pessah I, Restifo L, Threadgill DW. Animal models of autism spectrum disorders: information for neurotoxicologists. Neurotoxicology. 30: 811-21. PMID 19596370 DOI: 10.1016/J.Neuro.2009.07.002  0.8
2008 Lim J, Crespo-Barreto J, Jafar-Nejad P, Bowman AB, Richman R, Hill DE, Orr HT, Zoghbi HY. Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1. Nature. 452: 713-8. PMID 18337722 DOI: 10.1038/Nature06731  0.8
2007 Bowman AB, Lam YC, Jafar-Nejad P, Chen HK, Richman R, Samaco RC, Fryer JD, Kahle JJ, Orr HT, Zoghbi HY. Duplication of Atxn1l suppresses SCA1 neuropathology by decreasing incorporation of polyglutamine-expanded ataxin-1 into native complexes. Nature Genetics. 39: 373-9. PMID 17322884 DOI: 10.1038/Ng1977  0.8
2006 Lam YC, Bowman AB, Jafar-Nejad P, Lim J, Richman R, Fryer JD, Hyun ED, Duvick LA, Orr HT, Botas J, Zoghbi HY. ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology. Cell. 127: 1335-47. PMID 17190598 DOI: 10.1016/J.Cell.2006.11.038  0.8
2006 Helmlinger D, Hardy S, Abou-Sleymane G, Eberlin A, Bowman AB, Gansmüller A, Picaud S, Zoghbi HY, Trottier Y, Tora L, Devys D. Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction. Plos Biology. 4: e67. PMID 16494529 DOI: 10.1371/journal.pbio.0040067  0.8
2005 Young JI, Hong EP, Castle JC, Crespo-Barreto J, Bowman AB, Rose MF, Kang D, Richman R, Johnson JM, Berget S, Zoghbi HY. Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2. Proceedings of the National Academy of Sciences of the United States of America. 102: 17551-8. PMID 16251272 DOI: 10.1073/Pnas.0507856102  0.8
2005 Bowman AB, Yoo SY, Dantuma NP, Zoghbi HY. Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation. Human Molecular Genetics. 14: 679-91. PMID 15661755 DOI: 10.1093/hmg/ddi064  0.8
2003 Bowman AB, Levorse JM, Ingram RS, Tilghman SM. Functional characterization of a testis-specific DNA binding activity at the H19/Igf2 imprinting control region. Molecular and Cellular Biology. 23: 8345-51. PMID 14585991 DOI: 10.1128/MCB.23.22.8345-8351.2003  0.8
2000 Bowman AB, Kamal A, Ritchings BW, Philp AV, McGrail M, Gindhart JG, Goldstein LS. Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein. Cell. 103: 583-94. PMID 11106729 DOI: 10.1016/S0092-8674(00)00162-8  0.8
1999 Bowman AB, Patel-King RS, Benashski SE, McCaffery JM, Goldstein LS, King SM. Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis. The Journal of Cell Biology. 146: 165-80. PMID 10402468 DOI: 10.1083/jcb.146.1.165  0.8
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