☰

Ivan P. Moskowitz - Publications

Affiliations: 
Pediatrics, Pathology, and Human Genetics University of Chicago, Chicago, IL 
Tree Info Similar researchers PubMed Report error

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Broman MT, Nadadur RD, Perez-Cervantes C, Burnicka-Turek O, Lazarevic S, Gams A, Laforest B, Steimle JD, Iddir S, Wang Z, Smith L, Mazurek SR, Olivey HE, Zhou P, Gadek M, ... ... Moskowitz IP, et al. A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network. Circulation. PMID 38189150 DOI: 10.1161/CIRCULATIONAHA.123.066804  0.777
2023 Sweat ME, Cao Y, Zhang X, Burnicka-Turek O, Perez-Cervantes C, Arulsamy K, Lu F, Keating EM, Akerberg BN, Ma Q, Wakimoto H, Gorham JM, Hill LD, Kyoung Song M, Trembley MA, ... ... Moskowitz IP, et al. Tbx5 maintains atrial identity in post-natal cardiomyocytes by regulating an atrial-specific enhancer network. Nature Cardiovascular Research. 2: 881-898. PMID 38344303 DOI: 10.1038/s44161-023-00334-7  0.428
2023 Yamaguchi N, Chang EW, Lin Z, Shekhar A, Bu L, Khodadadi-Jamayran A, Tsirigos A, Cen Y, Phoon CKL, Moskowitz IP, Park DS. An Anterior Second Heart Field Enhancer Regulates the Gene Regulatory Network of the Cardiac Outflow Tract. Circulation. PMID 37772400 DOI: 10.1161/CIRCULATIONAHA.123.065700  0.466
2023 En A, Bogireddi H, Thomas B, Stutzman A, Ikegami S, LaForest B, Almakki O, Pytel P, Moskowitz IP, Ikegami K. The cGAS-STING pathway is dispensable in a mouse model of -cardiomyopathy despite nuclear envelope rupture. Biorxiv : the Preprint Server For Biology. PMID 37693381 DOI: 10.1101/2023.08.28.555134  0.347
2023 Selewa A, Luo K, Wasney M, Smith L, Sun X, Tang C, Eckart H, Moskowitz IP, Basu A, He X, Pott S. Single-cell genomics improves the discovery of risk variants and genes of atrial fibrillation. Nature Communications. 14: 4999. PMID 37591828 DOI: 10.1038/s41467-023-40505-5  0.361
2023 Steimle JD, Kim C, Rowton M, Nadadur RD, Wang Z, Stocker M, Hoffmann AD, Hanson E, Kweon J, Sinha T, Choi K, Black BL, Cunningham JM, Moskowitz IP, Ikegami K. ETV2 primes hematoendothelial gene enhancers prior to hematoendothelial fate commitment. Cell Reports. 42: 112665. PMID 37330911 DOI: 10.1016/j.celrep.2023.112665  0.757
2023 Sweat ME, Cao Y, Zhang X, Burnicka-Turek O, Perez-Cervantes C, Akerberg BN, Ma Q, Wakimoto H, Gorham JM, Song MK, Trembley MA, Wang P, Lu F, Gianeselli M, Prondzynski M, ... ... Moskowitz IP, et al. maintains atrial identity by regulating an atrial enhancer network. Biorxiv : the Preprint Server For Biology. PMID 37131696 DOI: 10.1101/2023.04.21.537535  0.423
2022 Bersell KR, Yang T, Mosley JD, Glazer AM, Hale AT, Kryshtal DO, Kim K, Steimle JD, Brown JD, Salem JE, Campbell CC, Hong CC, Wells QS, Johnson AN, Short L, ... ... Moskowitz IP, et al. Transcriptional Dysregulation Underlies Both Monogenic Arrhythmia Syndrome and Common Modifiers of Cardiac Repolarization. Circulation. PMID 36524479 DOI: 10.1161/CIRCULATIONAHA.122.062193  0.771
2022 Rowton M, Perez-Cervantes C, Hur S, Jacobs-Li J, Lu E, Deng N, Guzzetta A, Hoffmann AD, Stocker M, Steimle JD, Lazarevic S, Oubaha S, Yang XH, Kim C, Yu S, ... ... Moskowitz IP, et al. Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages. Developmental Cell. PMID 36108627 DOI: 10.1016/j.devcel.2022.08.009  0.785
2021 Rankin SA, Steimle JD, Yang XH, Rydeen AB, Agarwal K, Chaturvedi P, Ikegami K, Herriges MJ, Moskowitz IP, Zorn AM. Tbx5 drives expression to regulate a RA-Hedgehog-Wnt gene regulatory network coordinating cardiopulmonary development. Elife. 10. PMID 34643182 DOI: 10.7554/eLife.69288  0.78
2021 Rowton M, Guzzetta A, Rydeen AB, Moskowitz IP. Control of cardiomyocyte differentiation timing by intercellular signaling pathways. Seminars in Cell & Developmental Biology. 118: 94-106. PMID 34144893 DOI: 10.1016/j.semcdb.2021.06.002  0.334
2020 Lipovsky CE, Jimenez J, Guo Q, Li G, Yin T, Hicks S, Bhatnagar S, Takahashi K, Zhang DM, Brumback BD, Goldsztejn U, Nadadur RD, Perez-Cervantes C, Moskowitz IP, Liu S, et al. Chamber-specific transcriptional responses in atrial fibrillation. Jci Insight. PMID 32841220 DOI: 10.1172/Jci.Insight.135319  0.411
2020 van Ouwerkerk AF, Hall AW, Kadow ZA, Lazarevic S, Reyat JS, Tucker NR, Nadadur RD, Bosada FM, Bianchi V, Ellinor PT, Fabritz L, Martin JF, de Laat W, Kirchhof P, Moskowitz IP, et al. Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation. Circulation Research. 127: 34-50. PMID 32717170 DOI: 10.1161/CIRCRESAHA.120.316574  0.6
2020 Guzzetta A, Koska M, Rowton M, Sullivan KR, Jacobs-Li J, Kweon J, Hidalgo H, Eckart H, Hoffmann AD, Back R, Lozano S, Moon AM, Basu A, Bressan M, Pott S, ... Moskowitz IP, et al. Hedgehog-FGF signaling axis patterns anterior mesoderm during gastrulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32561646 DOI: 10.1073/Pnas.1914167117  0.756
2020 Dai W, Nadadur RD, Brennan J, Smith HL, Shen KM, Gadek M, Laforest B, Wang M, Gemel J, Li Y, Zhang J, Ziman BD, Yan J, Ai X, Beyer EC, ... ... Moskowitz IP, et al. ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction. Circulation Research. PMID 32347164 DOI: 10.1161/Circresaha.119.316415  0.327
2020 Burnicka-Turek O, Broman MT, Steimle JD, Boukens BJ, Petrenko N, Ikegami K, Nadadur RD, Qiao Y, Arnolds DE, Yang XH, Patel VV, Nobrega MA, Efimov IR, Moskowitz IP. Transcriptional Patterning of the Ventricular Cardiac Conduction System. Circulation Research. PMID 32290757 DOI: 10.1161/Circresaha.118.314460  0.792
2019 Laforest B, Dai W, Tyan L, Lazarevic S, Shen KM, Gadek M, Broman MT, Weber CR, Moskowitz IP. Atrial fibrillation risk loci interact to modulate Ca2+-dependent atrial rhythm homeostasis. The Journal of Clinical Investigation. PMID 31609246 DOI: 10.1172/Jci124231  0.346
2019 Liu J, Cheng H, Xiang M, Zhou L, Wu B, Moskowitz IP, Zhang K, Xie L. Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development. Plos Genetics. 15: e1007711. PMID 31120883 DOI: 10.1371/journal.pgen.1007711  0.42
2018 Steimle JD, Rankin SA, Slagle CE, Bekeny J, Rydeen AB, Chan SS, Kweon J, Yang XH, Ikegami K, Nadadur RD, Rowton M, Hoffmann AD, Lazarevic S, Thomas W, Boyle Anderson EAT, ... ... Moskowitz IP, et al. Evolutionarily conserved - pathway orchestrates cardiopulmonary development. Proceedings of the National Academy of Sciences of the United States of America. PMID 30352852 DOI: 10.1073/Pnas.1811624115  0.798
2018 Singh BN, Koyano-Nakagawa N, Gong W, Moskowitz IP, Weaver CV, Braunlin E, Das S, van Berlo JH, Garry MG, Garry DJ. A conserved HH-Gli1-Mycn network regulates heart regeneration from newt to human. Nature Communications. 9: 4237. PMID 30315164 DOI: 10.1038/S41467-018-06617-Z  0.414
2017 Yang XH, Nadadur RD, Hilvering CR, Bianchi V, Werner M, Mazurek SR, Gadek M, Shen KM, Goldman JA, Tyan L, Bekeny J, Hall JM, Lee N, Perez-Cervantes C, Burnicka-Turek O, ... ... Moskowitz IP, et al. Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm. Elife. 6. PMID 29280435 DOI: 10.7554/Elife.31683  0.435
2017 Werner MS, Sullivan MA, Shah RN, Nadadur RD, Grzybowski AT, Galat V, Moskowitz IP, Ruthenburg AJ. Chromatin-enriched lncRNAs can act as cell-type specific activators of proximal gene transcription. Nature Structural & Molecular Biology. PMID 28628087 DOI: 10.1038/Nsmb.3424  0.302
2017 Zhou L, Liu J, Xiang M, Olson P, Guzzetta A, Zhang K, Moskowitz IP, Xie L. Gata4 potentiates second heart field proliferation and Hedgehog signaling for cardiac septation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28167794 DOI: 10.1073/pnas.1605137114  0.466
2016 Hoffmann AD, Yang XH, Burnicka-Turek O, Bosman JD, Ren X, Xie L, Steimle JD, Vokes SA, McMahon AP, Kalinichenko VV, Moskowitz IP. Correction: Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation. Plos Genetics. 12: e1006533. PMID 28033319 DOI: 10.1371/Journal.Pgen.1006533  0.776
2016 Nadadur RD, Broman MT, Boukens B, Mazurek SR, Yang X, van den Boogaard M, Bekeny J, Gadek M, Ward T, Zhang M, Qiao Y, Martin JF, Seidman CE, Seidman J, Christoffels V, ... ... Moskowitz IP, et al. Pitx2 modulates a Tbx5-dependent gene regulatory network to maintain atrial rhythm. Science Translational Medicine. 8: 354ra115. PMID 27582060 DOI: 10.1126/Scitranslmed.Aaf4891  0.639
2016 Burnicka-Turek O, Steimle JD, Huang W, Felker L, Kamp A, Kweon J, Peterson M, Reeves RH, Maslen CL, Gruber PJ, Yang XH, Shendure J, Moskowitz IP. Cilia Gene Mutations Cause Atrioventricular Septal Defects by Multiple Mechanisms. Human Molecular Genetics. PMID 27340223 DOI: 10.1093/Hmg/Ddw155  0.774
2016 Priest JR, Osoegawa K, Mohammed N, Nanda V, Kundu R, Schultz K, Lammer EJ, Girirajan S, Scheetz T, Waggott D, Haddad F, Reddy S, Bernstein D, Burns T, Steimle JD, ... ... Moskowitz IP, et al. De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects. Plos Genetics. 12: e1005963. PMID 27058611 DOI: 10.1371/Journal.Pgen.1005963  0.783
2016 Waldron L, Steimle JD, Greco TM, Gomez NC, Dorr KM, Kweon J, Temple B, Yang XH, Wilczewski CM, Davis IJ, Cristea IM, Moskowitz IP, Conlon FL. The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation. Developmental Cell. 36: 262-75. PMID 26859351 DOI: 10.1016/J.Devcel.2016.01.009  0.81
2015 Rowton M, Moskowitz IP. Many ways to break a heart. Elife. 4. PMID 26305497 DOI: 10.7554/eLife.10040  0.379
2015 Polk RC, Gergics P, Steimle JD, Li H, Moskowitz IP, Camper SA, Reeves RH. The pattern of congenital heart defects arising from reduced Tbx5 expression is altered in a Down syndrome mouse model. Bmc Developmental Biology. 15: 30. PMID 26208718 DOI: 10.1186/s12861-015-0080-y  0.78
2015 Shamis Y, Cullen DE, Liu L, Yang G, Ng SF, Xiao L, Bell FT, Ray C, Takikawa S, Moskowitz IP, Cai CL, Yang X, Li X. Maternal and zygotic Zfp57 modulate NOTCH signaling in cardiac development. Proceedings of the National Academy of Sciences of the United States of America. 112: E2020-9. PMID 25848000 DOI: 10.1073/Pnas.1415541112  0.443
2015 Quintero-Rivera F, Xi QJ, Keppler-Noreuil KM, Lee JH, Higgins AW, Anchan RM, Roberts AE, Seong IS, Fan X, Lage K, Lu LY, Tao J, Hu X, Berezney R, Gelb BD, ... ... Moskowitz IP, et al. MATR3 disruption in human and mouse associated with bicuspid aortic valve, aortic coarctation and patent ductus arteriosus. Human Molecular Genetics. 24: 2375-89. PMID 25574029 DOI: 10.1093/Hmg/Ddv004  0.38
2014 Hoffmann AD, Yang XH, Burnicka-Turek O, Bosman JD, Ren X, Steimle JD, Vokes SA, McMahon AP, Kalinichenko VV, Moskowitz IP. Foxf genes integrate tbx5 and hedgehog pathways in the second heart field for cardiac septation. Plos Genetics. 10: e1004604. PMID 25356765 DOI: 10.1371/Journal.Pgen.1004604  0.809
2014 van den Boogaard M, Smemo S, Burnicka-Turek O, Arnolds DE, van de Werken HJ, Klous P, McKean D, Muehlschlegel JD, Moosmann J, Toka O, Yang XH, Koopmann TT, Adriaens ME, Bezzina CR, de Laat W, ... ... Moskowitz IP, et al. A common genetic variant within SCN10A modulates cardiac SCN5A expression. The Journal of Clinical Investigation. 124: 1844-52. PMID 24642470 DOI: 10.1172/Jci73140  0.788
2012 Xie L, Hoffmann AD, Burnicka-Turek O, Friedland-Little JM, Zhang K, Moskowitz IP. Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation. Developmental Cell. 23: 280-91. PMID 22898775 DOI: 10.1016/J.Devcel.2012.06.006  0.82
2012 Arnolds DE, Liu F, Fahrenbach JP, Kim GH, Schillinger KJ, Smemo S, McNally EM, Nobrega MA, Patel VV, Moskowitz IP. TBX5 drives Scn5a expression to regulate cardiac conduction system function. The Journal of Clinical Investigation. 122: 2509-18. PMID 22728936 DOI: 10.1172/Jci62617  0.786
2012 Smemo S, Campos LC, Moskowitz IP, Krieger JE, Pereira AC, Nobrega MA. Regulatory variation in a TBX5 enhancer leads to isolated congenital heart disease. Human Molecular Genetics. 21: 3255-63. PMID 22543974 DOI: 10.1093/Hmg/Dds165  0.417
2011 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J. Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. Journal of Molecular and Cellular Cardiology. 52: 638-49. PMID 22155005 DOI: 10.1016/j.yjmcc.2011.11.011  0.445
2011 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J. Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects. Plos One. 6: e20803. PMID 21677783 DOI: 10.1371/journal.pone.0020803  0.442
2011 Friedland-Little JM, Hoffmann AD, Ocbina PJ, Peterson MA, Bosman JD, Chen Y, Cheng SY, Anderson KV, Moskowitz IP. A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus. Human Molecular Genetics. 20: 3725-37. PMID 21653639 DOI: 10.1093/hmg/ddr241  0.727
2011 Wang J, Chen L, Wen S, Zhu H, Yu W, Moskowitz IP, Shaw GM, Finnell RH, Schwartz RJ. Defective sumoylation pathway directs congenital heart disease. Birth Defects Research. Part a, Clinical and Molecular Teratology. 91: 468-76. PMID 21563299 DOI: 10.1002/Bdra.20816  0.391
2011 Ocbina PJ, Eggenschwiler JT, Moskowitz I, Anderson KV. Complex interactions between genes controlling trafficking in primary cilia. Nature Genetics. 43: 547-53. PMID 21552265 DOI: 10.1038/Ng.832  0.307
2011 Arnolds DE, Chu A, McNally EM, Nobrega MA, Moskowitz IP. The emerging genetic landscape underlying cardiac conduction system function. Birth Defects Research. Part a, Clinical and Molecular Teratology. 91: 578-85. PMID 21538814 DOI: 10.1002/Bdra.20800  0.753
2011 Arnolds DE, Moskowitz IP. Inducible recombination in the cardiac conduction system of minK: CreERT² BAC transgenic mice. Genesis (New York, N.Y. : 2000). 49: 878-84. PMID 21504046 DOI: 10.1002/dvg.20759  0.741
2011 Moskowitz IP, Wang J, Peterson MA, Pu WT, Mackinnon AC, Oxburgh L, Chu GC, Sarkar M, Berul C, Smoot L, Robertson EJ, Schwartz R, Seidman JG, Seidman CE. Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected] Proceedings of the National Academy of Sciences of the United States of America. 108: 4006-11. PMID 21330551 DOI: 10.1073/pnas.1019025108  0.385
2010 Kamp A, Peterson MA, Svenson KL, Bjork BC, Hentges KE, Rajapaksha TW, Moran J, Justice MJ, Seidman JG, Seidman CE, Moskowitz IP, Beier DR. Genome-wide identification of mouse congenital heart disease loci. Human Molecular Genetics. 19: 3105-13. PMID 20511334 DOI: 10.1093/Hmg/Ddq211  0.369
2009 Dellefave LM, Pytel P, Mewborn S, Mora B, Guris DL, Fedson S, Waggoner D, Moskowitz I, McNally EM. Sarcomere mutations in cardiomyopathy with left ventricular hypertrabeculation. Circulation. Cardiovascular Genetics. 2: 442-9. PMID 20031619 DOI: 10.1161/Circgenetics.109.861955  0.303
2009 Hoffmann AD, Peterson MA, Friedland-Little JM, Anderson SA, Moskowitz IP. sonic hedgehog is required in pulmonary endoderm for atrial septation. Development (Cambridge, England). 136: 1761-70. PMID 19369393 DOI: 10.1242/dev.034157  0.786
2008 King JC, Moskowitz IP, Burgon PG, Ahmad F, Stone JR, Seidman JG, Lees JA. E2F3 plays an essential role in cardiac development and function. Cell Cycle (Georgetown, Tex.). 7: 3775-80. PMID 19029823 DOI: 10.4161/Cc.7.23.7240  0.461
2008 Ahmad F, Banerjee SK, Lage ML, Huang XN, Smith SH, Saba S, Rager J, Conner DA, Janczewski AM, Tobita K, Tinney JP, Moskowitz IP, Perez-Atayde AR, Keller BB, Mathier MA, et al. The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy. Plos One. 3: e2642. PMID 18612386 DOI: 10.1371/Journal.Pone.0002642  0.366
2007 Moskowitz IP, Kim JB, Moore ML, Wolf CM, Peterson MA, Shendure J, Nobrega MA, Yokota Y, Berul C, Izumo S, Seidman JG, Seidman CE. A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell. 129: 1365-76. PMID 17604724 DOI: 10.1016/J.Cell.2007.04.036  0.453
2007 Stroud DM, Darrow BJ, Kim SD, Zhang J, Jongbloed MR, Rentschler S, Moskowitz IP, Seidman J, Fishman GI. Complex genomic rearrangement in CCS-LacZ transgenic mice. Genesis (New York, N.Y. : 2000). 45: 76-82. PMID 17269130 DOI: 10.1002/Dvg.20267  0.364
2006 Feng Y, Chen MH, Moskowitz IP, Mendonza AM, Vidali L, Nakamura F, Kwiatkowski DJ, Walsh CA. Filamin A (FLNA) is required for cell-cell contact in vascular development and cardiac morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 19836-41. PMID 17172441 DOI: 10.1073/pnas.0609628104  0.324
2005 Wolf CM, Moskowitz IP, Arno S, Branco DM, Semsarian C, Bernstein SA, Peterson M, Maida M, Morley GE, Fishman G, Berul CI, Seidman CE, Seidman JG. Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia. Proceedings of the National Academy of Sciences of the United States of America. 102: 18123-8. PMID 16332958 DOI: 10.1073/Pnas.0509145102  0.411
2004 Moskowitz IP, Pizard A, Patel VV, Bruneau BG, Kim JB, Kupershmidt S, Roden D, Berul CI, Seidman CE, Seidman JG. The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system. Development (Cambridge, England). 131: 4107-16. PMID 15289437 DOI: 10.1242/Dev.01265  0.399
2003 Arad M, Moskowitz IP, Patel VV, Ahmad F, Perez-Atayde AR, Sawyer DB, Walter M, Li GH, Burgon PG, Maguire CT, Stapleton D, Schmitt JP, Guo XX, Pizard A, Kupershmidt S, et al. Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy. Circulation. 107: 2850-6. PMID 12782567 DOI: 10.1161/01.Cir.0000075270.13497.2B  0.352
Show low-probability matches.