| Year |
Citation |
Score |
| 2023 |
Gajendran N, Rajasekaran S, Witt SN. Knocking out alpha-synuclein in melanoma cells downregulates L1CAM and decreases motility. Scientific Reports. 13: 9243. PMID 37286800 DOI: 10.1038/s41598-023-36451-3 |
0.312 |
|
| 2022 |
Rajasekaran S, Patel D, Witt SN. α-synuclein and phosphoinositide-binding proteins: α-synuclein inhibits the association of PX- but not FYVE-containing proteins with vesicles in vivo. Biochemical and Biophysical Research Communications. 603: 7-12. PMID 35263697 DOI: 10.1016/j.bbrc.2022.01.101 |
0.587 |
|
| 2021 |
Rajasekaran S, Peterson PP, Liu Z, Robinson LC, Witt SN. α-Synuclein inhibits Snx3-retromer retrograde trafficking of the conserved membrane-bound proprotein convertase Kex2 in the secretory pathway of Saccharomyces cerevisiae. Human Molecular Genetics. PMID 34570221 DOI: 10.1093/hmg/ddab284 |
0.322 |
|
| 2021 |
Shekoohi S, Rajasekaran S, Patel D, Yang S, Liu W, Huang S, Yu X, Witt SN. Knocking out alpha-synuclein in melanoma cells dysregulates cellular iron metabolism and suppresses tumor growth. Scientific Reports. 11: 5267. PMID 33664298 DOI: 10.1038/s41598-021-84443-y |
0.685 |
|
| 2018 |
Patel D, Witt SN. Sorting Out the Role of α-Synuclein in Retromer-Mediated Endosomal Protein Sorting. Journal of Experimental Neuroscience. 12: 1179069518796215. PMID 30158827 DOI: 10.1177/1179069518796215 |
0.581 |
|
| 2018 |
Patel D, Xu C, Nagarajan S, Liu Z, Hemphill WO, Shi R, Uversky VN, Caldwell GA, Caldwell KA, Witt SN. Alpha-synuclein inhibits Snx3-retromer-mediated retrograde recycling of iron transporters in S. cerevisiae and C. elegans models of Parkinson's disease. Human Molecular Genetics. PMID 29452354 DOI: 10.1093/Hmg/Ddy059 |
0.539 |
|
| 2017 |
Patel D, Witt SN. Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease. Oxidative Medicine and Cellular Longevity. 2017: 4829180. PMID 28785375 DOI: 10.1155/2017/4829180 |
0.486 |
|
| 2016 |
Wang S, Zhang S, Xu C, Barron A, Galiano F, Patel D, Lee YJ, Caldwell GA, Caldwell KA, Witt SN. Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease. Plos One. 11: e0164465. PMID 27736935 DOI: 10.1371/Journal.Pone.0164465 |
0.541 |
|
| 2011 |
Liu X, Lee YJ, Liou LC, Ren Q, Zhang Z, Wang S, Witt SN. Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast. Human Molecular Genetics. 20: 3401-14. PMID 21642386 DOI: 10.1093/Hmg/Ddr246 |
0.306 |
|
| 2011 |
Lee YJ, Wang S, Slone SR, Yacoubian TA, Witt SN. Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease. Plos One. 6: e15946. PMID 21264320 DOI: 10.1371/Journal.Pone.0015946 |
0.3 |
|
| 2008 |
Liang J, Clark-Dixon C, Wang S, Flower TR, Williams-Hart T, Zweig R, Robinson LC, Tatchell K, Witt SN. Novel suppressors of alpha-synuclein toxicity identified using yeast. Human Molecular Genetics. 17: 3784-95. PMID 18772193 DOI: 10.1093/Hmg/Ddn276 |
0.68 |
|
| 2007 |
Flower TR, Clark-Dixon C, Metoyer C, Yang H, Shi R, Zhang Z, Witt SN. YGR198w (YPP1) targets A30P alpha-synuclein to the vacuole for degradation. The Journal of Cell Biology. 177: 1091-104. PMID 17576801 DOI: 10.1083/Jcb.200610071 |
0.668 |
|
| 2006 |
Witt SN, Flower TR. alpha-Synuclein, oxidative stress and apoptosis from the perspective of a yeast model of Parkinson's disease. Fems Yeast Research. 6: 1107-16. PMID 17156009 DOI: 10.1111/j.1567-1364.2006.00135.x |
0.677 |
|
| 2005 |
Flower TR, Chesnokova LS, Froelich CA, Dixon C, Witt SN. Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease. Journal of Molecular Biology. 351: 1081-100. PMID 16051265 DOI: 10.1016/J.Jmb.2005.06.060 |
0.674 |
|
| 2004 |
Flower TR, Witt SN. Mutational analysis of the yeast nucleotide exchange factor Mge1p Journal of the Chinese Chemical Society. 51: 1141-1146. |
0.655 |
|
| 2003 |
Chesnokova LS, Slepenkov SV, Protasevich II, Sehorn MG, Brouillette CG, Witt SN. Deletion of DnaK's lid strengthens binding to the nucleotide exchange factor, GrpE: a kinetic and thermodynamic analysis. Biochemistry. 42: 9028-40. PMID 12885236 DOI: 10.1021/Bi0346493 |
0.652 |
|
| 2002 |
Sehorn MG, Slepenkov SV, Witt SN. Characterization of two partially unfolded intermediates of the molecular chaperone DnaK at low pH. Biochemistry. 41: 8499-507. PMID 12081501 DOI: 10.1021/Bi025810X |
0.639 |
|
| 2001 |
Buczynski G, Slepenkov SV, Sehorn MG, Witt SN. Characterization of a lidless form of the molecular chaperone DnaK: Deletion of the lid increases peptide on- and off-rate constants Journal of Biological Chemistry. 276: 27231-27236. DOI: 10.1074/Jbc.M100237200 |
0.636 |
|
| 1990 |
Larsen RW, Li W, Copeland RA, Witt SN, Lou BS, Chan SI, Ondrias MR. Room temperature characterization of the dioxygen intermediates of cytochrome c oxidase by resonance Raman spectroscopy. Biochemistry. 29: 10135-40. PMID 2176863 DOI: 10.1021/Bi00495A018 |
0.579 |
|
| 1987 |
Witt SN, Chan SI. Evidence for a ferryl Fea3 in oxygenated cytochrome c oxidase Journal of Biological Chemistry. 262: 1446-1448. PMID 3027092 |
0.412 |
|
| 1986 |
Witt SN, Blair DF, Chan SI. Chemical and spectroscopic evidence for the formation of a ferryl Fe(α3) intermediate during turnover of cytochrome c oxidase Journal of Biological Chemistry. 261: 8104-8107. PMID 3013842 |
0.438 |
|
| 1986 |
BLAIR DF, WITT SN, CHAN SI. ChemInform Abstract: Mechanism of Cytochrome c Oxidase-Catalyzed Dioxygen Reduction at Low Temperatures. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198613334 |
0.413 |
|
| 1985 |
Blair DF, Witt SN, Chan SI. Mechanism of cytochrome c oxidase-catalyzed dioxygen reduction at low temperatures. Evidence for two intermediates at the three-electron level and entropic promotion of the bond-breaking step Journal of the American Chemical Society. 107: 7389-7399. DOI: 10.1021/Ja00311A029 |
0.405 |
|
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