| Year |
Citation |
Score |
| 2024 |
Zaino AM, Dash RC, James SJ, MacGilvary N, Crompton A, McPherson KS, Stanzione M, Korzhnev DM, Dyson NJ, Chatterjee N, Cantor SB, Hadden MK. Lead compound profiling for small molecule inhibitors of the REV1-CT/RIR Translesion synthesis Protein-Protein interaction. Bioorganic & Medicinal Chemistry. 106: 117755. PMID 38749343 DOI: 10.1016/j.bmc.2024.117755 |
0.378 |
|
| 2024 |
Cong K, MacGilvary N, Lee S, MacLeod SG, Calvo J, Peng M, Nedergaard Kousholt A, Day TA, Cantor SB. FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells. Nature Communications. 15: 2599. PMID 38521768 DOI: 10.1038/s41467-024-46824-5 |
0.364 |
|
| 2024 |
Cong K, MacGilvary N, Lee S, MacLeod SG, Calvo J, Peng M, Kousholt AN, Day T, Cantor SB. FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells. Biorxiv : the Preprint Server For Biology. PMID 38260529 DOI: 10.1101/2024.01.04.574095 |
0.35 |
|
| 2023 |
Whalen JM, Cantor SB. Unveiling the toxicity of single-stranded DNA gaps through a yeast model. Nature Structural & Molecular Biology. 30: 870-872. PMID 37415010 DOI: 10.1038/s41594-023-01031-6 |
0.377 |
|
| 2022 |
Cong K, Cantor SB. Exploiting replication gaps for cancer therapy. Molecular Cell. PMID 35568026 DOI: 10.1016/j.molcel.2022.04.023 |
0.468 |
|
| 2021 |
Cantor SB. Revisiting the BRCA-pathway through the lens of replication gap suppression: "Gaps determine therapy response in BRCA mutant cancer". Dna Repair. 107: 103209. PMID 34419699 DOI: 10.1016/j.dnarep.2021.103209 |
0.488 |
|
| 2021 |
Cong K, Peng M, Kousholt AN, Lee WTC, Lee S, Nayak S, Krais J, VanderVere-Carozza PS, Pawelczak KS, Calvo J, Panzarino NJ, Jonkers J, Johnson N, Turchi JJ, Rothenberg E, ... Cantor SB, et al. Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency. Molecular Cell. PMID 34216544 DOI: 10.1016/j.molcel.2021.06.011 |
0.391 |
|
| 2021 |
Lee WTC, Yin Y, Morten MJ, Tonzi P, Gwo PP, Odermatt DC, Modesti M, Cantor SB, Gari K, Huang TT, Rothenberg E. Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling. Nature Communications. 12: 2525. PMID 33953191 DOI: 10.1038/s41467-021-22830-9 |
0.309 |
|
| 2021 |
Nayak S, Calvo JA, Cantor SB. Targeting translesion synthesis (TLS) to expose replication gaps, a unique cancer vulnerability. Expert Opinion On Therapeutic Targets. 25: 27-36. PMID 33416413 DOI: 10.1080/14728222.2021.1864321 |
0.348 |
|
| 2020 |
Panzarino NJ, Krais JJ, Cong K, Peng M, Mosqueda M, Nayak SU, Bond SM, Calvo JA, Doshi MB, Bere M, Ou J, Deng B, Zhu LJ, Johnson N, Cantor SB. Replication Gaps Underlie BRCA-deficiency and Therapy Response. Cancer Research. PMID 33184108 DOI: 10.1158/0008-5472.CAN-20-1602 |
0.411 |
|
| 2020 |
Awate S, Sommers JA, Datta A, Nayak S, Bellani MA, Yang O, Dunn CA, Nicolae CM, Moldovan GL, Seidman MM, Cantor SB, Brosh RM. FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links. Nucleic Acids Research. PMID 32797166 DOI: 10.1093/nar/gkaa660 |
0.47 |
|
| 2020 |
Nayak S, Calvo JA, Cong K, Peng M, Berthiaume E, Jackson J, Zaino AM, Vindigni A, Hadden MK, Cantor SB. Inhibition of the translesion synthesis polymerase REV1 exploits replication gaps as a cancer vulnerability. Science Advances. 6: eaaz7808. PMID 32577513 DOI: 10.1126/sciadv.aaz7808 |
0.38 |
|
| 2019 |
Cantor S. TPX2 joins 53BP1 to maintain DNA repair and fork stability. The Journal of Cell Biology. PMID 30635354 DOI: 10.1083/jcb.201812142 |
0.388 |
|
| 2018 |
Peng M, Cong K, Panzarino NJ, Nayak S, Calvo J, Deng B, Zhu LJ, Morocz M, Hegedus L, Haracska L, Cantor SB. Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress. Cell Reports. 24: 3251-3261. PMID 30232006 DOI: 10.1016/j.celrep.2018.08.065 |
0.39 |
|
| 2017 |
Wang Y, Ung MH, Cantor S, Cheng C. Computational Investigation of Homologous Recombination DNA Repair Deficiency in Sporadic Breast Cancer. Scientific Reports. 7: 15742. PMID 29146938 DOI: 10.1038/s41598-017-16138-2 |
0.388 |
|
| 2016 |
Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, ... ... Cantor SB, et al. Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature. 535: 382-7. PMID 27443740 DOI: 10.1038/Nature18325 |
0.444 |
|
| 2015 |
Guillemette S, Serra RW, Peng M, Hayes JA, Konstantinopoulos PA, Green MR, Cantor SB. Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4. Genes & Development. 29: 489-94. PMID 25737278 DOI: 10.1101/Gad.256214.114 |
0.435 |
|
| 2014 |
Cantor SB, Brosh RM. What is wrong with Fanconi anemia cells? Cell Cycle (Georgetown, Tex.). 13: 3823-7. PMID 25486020 DOI: 10.4161/15384101.2014.980633 |
0.423 |
|
| 2014 |
Brosh RM, Cantor SB. Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia. Frontiers in Genetics. 5: 372. PMID 25374583 DOI: 10.3389/fgene.2014.00372 |
0.502 |
|
| 2014 |
Peng M, Xie J, Ucher A, Stavnezer J, Cantor SB. Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses. The Embo Journal. 33: 1698-712. PMID 24966277 DOI: 10.15252/embj.201387530 |
0.46 |
|
| 2014 |
Guillemette S, Branagan A, Peng M, Dhruva A, Schärer OD, Cantor SB. FANCJ localization by mismatch repair is vital to maintain genomic integrity after UV irradiation. Cancer Research. 74: 932-44. PMID 24351291 DOI: 10.1158/0008-5472.Can-13-2474 |
0.5 |
|
| 2013 |
Suhasini AN, Sommers JA, Muniandy PA, Coulombe Y, Cantor SB, Masson JY, Seidman MM, Brosh RM. Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response Molecular and Cellular Biology. 33: 2212-2227. PMID 23530059 DOI: 10.1128/MCB.01256-12 |
0.453 |
|
| 2012 |
Xie J, Peng M, Guillemette S, Quan S, Maniatis S, Wu Y, Venkatesh A, Shaffer SA, Brosh RM, Cantor SB. FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response. Plos Genetics. 8: e1002786. PMID 22792074 DOI: 10.1371/Journal.Pgen.1002786 |
0.449 |
|
| 2011 |
Cantor SB, Guillemette S. Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1. Future Oncology (London, England). 7: 253-61. PMID 21345144 DOI: 10.2217/fon.10.191 |
0.516 |
|
| 2011 |
Suhasini AN, Rawtani NA, Wu Y, Sommers JA, Sharma S, Mosedale G, North PS, Cantor SB, Hickson ID, Brosh RM. Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome. The Embo Journal. 30: 692-705. PMID 21240188 DOI: 10.1038/emboj.2010.362 |
0.352 |
|
| 2010 |
Xie J, Guillemette S, Peng M, Gilbert C, Buermeyer A, Cantor SB. An MLH1 mutation links BACH1/FANCJ to colon cancer, signaling, and insight toward directed therapy. Cancer Prevention Research (Philadelphia, Pa.). 3: 1409-16. PMID 20978114 DOI: 10.1158/1940-6207.CAPR-10-0118 |
0.382 |
|
| 2010 |
Cantor SB, Xie J. Assessing the link between BACH1/FANCJ and MLH1 in DNA crosslink repair. Environmental and Molecular Mutagenesis. 51: 500-7. PMID 20658644 DOI: 10.1002/em.20568 |
0.566 |
|
| 2009 |
Sommers JA, Rawtani N, Gupta R, Bugreev DV, Mazin AV, Cantor SB, Brosh RM. FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange Journal of Biological Chemistry. 284: 7505-7517. PMID 19150983 DOI: 10.1074/jbc.M809019200 |
0.502 |
|
| 2009 |
Siehler SY, Schrauder M, Gerischer U, Cantor S, Marra G, Wiesmüller L. Human MutL-complexes monitor homologous recombination independently of mismatch repair. Dna Repair. 8: 242-52. PMID 19022408 DOI: 10.1016/j.dnarep.2008.10.011 |
0.428 |
|
| 2008 |
Barber LJ, Youds JL, Ward JD, McIlwraith MJ, O'Neil NJ, Petalcorin MI, Martin JS, Collis SJ, Cantor SB, Auclair M, Tissenbaum H, West SC, Rose AM, Boulton SJ. RTEL1 maintains genomic stability by suppressing homologous recombination. Cell. 135: 261-71. PMID 18957201 DOI: 10.1016/J.Cell.2008.08.016 |
0.316 |
|
| 2008 |
Litman R, Gupta R, Brosh RM, Cantor SB. BRCA-FA pathway as a target for anti-tumor drugs. Anti-Cancer Agents in Medicinal Chemistry. 8: 426-30. PMID 18473727 DOI: 10.2174/187152008784220285 |
0.372 |
|
| 2007 |
Gupta R, Sharma S, Sommers JA, Kenny MK, Cantor SB, Brosh RM. FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein. Blood. 110: 2390-8. PMID 17596542 DOI: 10.1182/BLOOD-2006-11-057273 |
0.522 |
|
| 2007 |
Peng M, Litman R, Xie J, Sharma S, Brosh RM, Cantor SB. The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells. The Embo Journal. 26: 3238-49. PMID 17581638 DOI: 10.1038/sj.emboj.7601754 |
0.469 |
|
| 2006 |
Gupta R, Sharma S, Doherty KM, Sommers JA, Cantor SB, Brosh RM. Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand. Nucleic Acids Research. 34: 6673-83. PMID 17145708 DOI: 10.1093/nar/gkl964 |
0.458 |
|
| 2006 |
Greenberg RA, Sobhian B, Pathania S, Cantor SB, Nakatani Y, Livingston DM. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes & Development. 20: 34-46. PMID 16391231 DOI: 10.1101/Gad.1381306 |
0.505 |
|
| 2006 |
Cantor SB, Andreassen PR. Assessing the link between BACH1 and BRCA1 in the FA pathway. Cell Cycle (Georgetown, Tex.). 5: 164-7. PMID 16357529 DOI: 10.4161/cc.5.2.2338 |
0.362 |
|
| 2005 |
Gupta R, Sharma S, Sommers JA, Jin Z, Cantor SB, Brosh RM. Analysis of the DNA substrate specificity of the human BACH1 helicase associated with breast cancer. The Journal of Biological Chemistry. 280: 25450-60. PMID 15878853 DOI: 10.1074/JBC.M501995200 |
0.452 |
|
| 2004 |
Cantor S, Drapkin R, Zhang F, Lin Y, Han J, Pamidi S, Livingston DM. The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations Proceedings of the National Academy of Sciences of the United States of America. 101: 2357-2362. PMID 14983014 DOI: 10.1073/Pnas.0308717101 |
0.437 |
|
| 2002 |
Joo WS, Jeffrey PD, Cantor SB, Finnin MS, Livingston DM, Pavletich NP. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure Genes and Development. 16: 583-593. PMID 11877378 DOI: 10.1101/Gad.959202 |
0.484 |
|
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