39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zaino AM, Dash RC, James SJ, MacGilvary N, Crompton A, McPherson KS, Stanzione M, Korzhnev DM, Dyson NJ, Chatterjee N, Cantor SB, Hadden MK. Lead compound profiling for small molecule inhibitors of the REV1-CT/RIR Translesion synthesis Protein-Protein interaction. Bioorganic & Medicinal Chemistry. 106: 117755. PMID 38749343 DOI: 10.1016/j.bmc.2024.117755  0.379
2024 Cong K, MacGilvary N, Lee S, MacLeod SG, Calvo J, Peng M, Nedergaard Kousholt A, Day TA, Cantor SB. FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells. Nature Communications. 15: 2599. PMID 38521768 DOI: 10.1038/s41467-024-46824-5  0.364
2024 Cong K, MacGilvary N, Lee S, MacLeod SG, Calvo J, Peng M, Kousholt AN, Day T, Cantor SB. FANCJ promotes PARP1 activity during DNA replication that is essential in BRCA1 deficient cells. Biorxiv : the Preprint Server For Biology. PMID 38260529 DOI: 10.1101/2024.01.04.574095  0.351
2023 Whalen JM, Cantor SB. Unveiling the toxicity of single-stranded DNA gaps through a yeast model. Nature Structural & Molecular Biology. 30: 870-872. PMID 37415010 DOI: 10.1038/s41594-023-01031-6  0.377
2022 Cong K, Cantor SB. Exploiting replication gaps for cancer therapy. Molecular Cell. PMID 35568026 DOI: 10.1016/j.molcel.2022.04.023  0.469
2021 Cantor SB. Revisiting the BRCA-pathway through the lens of replication gap suppression: "Gaps determine therapy response in BRCA mutant cancer". Dna Repair. 107: 103209. PMID 34419699 DOI: 10.1016/j.dnarep.2021.103209  0.489
2021 Cong K, Peng M, Kousholt AN, Lee WTC, Lee S, Nayak S, Krais J, VanderVere-Carozza PS, Pawelczak KS, Calvo J, Panzarino NJ, Jonkers J, Johnson N, Turchi JJ, Rothenberg E, ... Cantor SB, et al. Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency. Molecular Cell. PMID 34216544 DOI: 10.1016/j.molcel.2021.06.011  0.391
2021 Lee WTC, Yin Y, Morten MJ, Tonzi P, Gwo PP, Odermatt DC, Modesti M, Cantor SB, Gari K, Huang TT, Rothenberg E. Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinders local replication stress signaling. Nature Communications. 12: 2525. PMID 33953191 DOI: 10.1038/s41467-021-22830-9  0.309
2021 Nayak S, Calvo JA, Cantor SB. Targeting translesion synthesis (TLS) to expose replication gaps, a unique cancer vulnerability. Expert Opinion On Therapeutic Targets. 25: 27-36. PMID 33416413 DOI: 10.1080/14728222.2021.1864321  0.349
2020 Panzarino NJ, Krais JJ, Cong K, Peng M, Mosqueda M, Nayak SU, Bond SM, Calvo JA, Doshi MB, Bere M, Ou J, Deng B, Zhu LJ, Johnson N, Cantor SB. Replication Gaps Underlie BRCA-deficiency and Therapy Response. Cancer Research. PMID 33184108 DOI: 10.1158/0008-5472.CAN-20-1602  0.412
2020 Awate S, Sommers JA, Datta A, Nayak S, Bellani MA, Yang O, Dunn CA, Nicolae CM, Moldovan GL, Seidman MM, Cantor SB, Brosh RM. FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links. Nucleic Acids Research. PMID 32797166 DOI: 10.1093/nar/gkaa660  0.47
2020 Nayak S, Calvo JA, Cong K, Peng M, Berthiaume E, Jackson J, Zaino AM, Vindigni A, Hadden MK, Cantor SB. Inhibition of the translesion synthesis polymerase REV1 exploits replication gaps as a cancer vulnerability. Science Advances. 6: eaaz7808. PMID 32577513 DOI: 10.1126/sciadv.aaz7808  0.38
2019 Cantor S. TPX2 joins 53BP1 to maintain DNA repair and fork stability. The Journal of Cell Biology. PMID 30635354 DOI: 10.1083/jcb.201812142  0.388
2018 Peng M, Cong K, Panzarino NJ, Nayak S, Calvo J, Deng B, Zhu LJ, Morocz M, Hegedus L, Haracska L, Cantor SB. Opposing Roles of FANCJ and HLTF Protect Forks and Restrain Replication during Stress. Cell Reports. 24: 3251-3261. PMID 30232006 DOI: 10.1016/j.celrep.2018.08.065  0.391
2017 Wang Y, Ung MH, Cantor S, Cheng C. Computational Investigation of Homologous Recombination DNA Repair Deficiency in Sporadic Breast Cancer. Scientific Reports. 7: 15742. PMID 29146938 DOI: 10.1038/s41598-017-16138-2  0.39
2016 Ray Chaudhuri A, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, ... ... Cantor SB, et al. Replication fork stability confers chemoresistance in BRCA-deficient cells. Nature. 535: 382-7. PMID 27443740 DOI: 10.1038/Nature18325  0.445
2015 Guillemette S, Serra RW, Peng M, Hayes JA, Konstantinopoulos PA, Green MR, Cantor SB. Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4. Genes & Development. 29: 489-94. PMID 25737278 DOI: 10.1101/Gad.256214.114  0.436
2014 Cantor SB, Brosh RM. What is wrong with Fanconi anemia cells? Cell Cycle (Georgetown, Tex.). 13: 3823-7. PMID 25486020 DOI: 10.4161/15384101.2014.980633  0.424
2014 Brosh RM, Cantor SB. Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemia. Frontiers in Genetics. 5: 372. PMID 25374583 DOI: 10.3389/fgene.2014.00372  0.503
2014 Peng M, Xie J, Ucher A, Stavnezer J, Cantor SB. Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses. The Embo Journal. 33: 1698-712. PMID 24966277 DOI: 10.15252/embj.201387530  0.46
2014 Guillemette S, Branagan A, Peng M, Dhruva A, Schärer OD, Cantor SB. FANCJ localization by mismatch repair is vital to maintain genomic integrity after UV irradiation. Cancer Research. 74: 932-44. PMID 24351291 DOI: 10.1158/0008-5472.Can-13-2474  0.501
2013 Suhasini AN, Sommers JA, Muniandy PA, Coulombe Y, Cantor SB, Masson JY, Seidman MM, Brosh RM. Fanconi anemia group J helicase and MRE11 nuclease interact to facilitate the DNA damage response Molecular and Cellular Biology. 33: 2212-2227. PMID 23530059 DOI: 10.1128/MCB.01256-12  0.453
2012 Xie J, Peng M, Guillemette S, Quan S, Maniatis S, Wu Y, Venkatesh A, Shaffer SA, Brosh RM, Cantor SB. FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response. Plos Genetics. 8: e1002786. PMID 22792074 DOI: 10.1371/Journal.Pgen.1002786  0.449
2011 Cantor SB, Guillemette S. Hereditary breast cancer and the BRCA1-associated FANCJ/BACH1/BRIP1. Future Oncology (London, England). 7: 253-61. PMID 21345144 DOI: 10.2217/fon.10.191  0.518
2011 Suhasini AN, Rawtani NA, Wu Y, Sommers JA, Sharma S, Mosedale G, North PS, Cantor SB, Hickson ID, Brosh RM. Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome. The Embo Journal. 30: 692-705. PMID 21240188 DOI: 10.1038/emboj.2010.362  0.352
2010 Xie J, Guillemette S, Peng M, Gilbert C, Buermeyer A, Cantor SB. An MLH1 mutation links BACH1/FANCJ to colon cancer, signaling, and insight toward directed therapy. Cancer Prevention Research (Philadelphia, Pa.). 3: 1409-16. PMID 20978114 DOI: 10.1158/1940-6207.CAPR-10-0118  0.383
2010 Cantor SB, Xie J. Assessing the link between BACH1/FANCJ and MLH1 in DNA crosslink repair. Environmental and Molecular Mutagenesis. 51: 500-7. PMID 20658644 DOI: 10.1002/em.20568  0.567
2009 Sommers JA, Rawtani N, Gupta R, Bugreev DV, Mazin AV, Cantor SB, Brosh RM. FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange Journal of Biological Chemistry. 284: 7505-7517. PMID 19150983 DOI: 10.1074/jbc.M809019200  0.503
2009 Siehler SY, Schrauder M, Gerischer U, Cantor S, Marra G, Wiesmüller L. Human MutL-complexes monitor homologous recombination independently of mismatch repair. Dna Repair. 8: 242-52. PMID 19022408 DOI: 10.1016/j.dnarep.2008.10.011  0.428
2008 Barber LJ, Youds JL, Ward JD, McIlwraith MJ, O'Neil NJ, Petalcorin MI, Martin JS, Collis SJ, Cantor SB, Auclair M, Tissenbaum H, West SC, Rose AM, Boulton SJ. RTEL1 maintains genomic stability by suppressing homologous recombination. Cell. 135: 261-71. PMID 18957201 DOI: 10.1016/J.Cell.2008.08.016  0.316
2008 Litman R, Gupta R, Brosh RM, Cantor SB. BRCA-FA pathway as a target for anti-tumor drugs. Anti-Cancer Agents in Medicinal Chemistry. 8: 426-30. PMID 18473727 DOI: 10.2174/187152008784220285  0.372
2007 Gupta R, Sharma S, Sommers JA, Kenny MK, Cantor SB, Brosh RM. FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein. Blood. 110: 2390-8. PMID 17596542 DOI: 10.1182/BLOOD-2006-11-057273  0.522
2007 Peng M, Litman R, Xie J, Sharma S, Brosh RM, Cantor SB. The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells. The Embo Journal. 26: 3238-49. PMID 17581638 DOI: 10.1038/sj.emboj.7601754  0.47
2006 Gupta R, Sharma S, Doherty KM, Sommers JA, Cantor SB, Brosh RM. Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand. Nucleic Acids Research. 34: 6673-83. PMID 17145708 DOI: 10.1093/nar/gkl964  0.459
2006 Greenberg RA, Sobhian B, Pathania S, Cantor SB, Nakatani Y, Livingston DM. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes & Development. 20: 34-46. PMID 16391231 DOI: 10.1101/Gad.1381306  0.506
2006 Cantor SB, Andreassen PR. Assessing the link between BACH1 and BRCA1 in the FA pathway. Cell Cycle (Georgetown, Tex.). 5: 164-7. PMID 16357529 DOI: 10.4161/cc.5.2.2338  0.363
2005 Gupta R, Sharma S, Sommers JA, Jin Z, Cantor SB, Brosh RM. Analysis of the DNA substrate specificity of the human BACH1 helicase associated with breast cancer. The Journal of Biological Chemistry. 280: 25450-60. PMID 15878853 DOI: 10.1074/JBC.M501995200  0.452
2004 Cantor S, Drapkin R, Zhang F, Lin Y, Han J, Pamidi S, Livingston DM. The BRCA1-associated protein BACH1 is a DNA helicase targeted by clinically relevant inactivating mutations Proceedings of the National Academy of Sciences of the United States of America. 101: 2357-2362. PMID 14983014 DOI: 10.1073/Pnas.0308717101  0.436
2002 Joo WS, Jeffrey PD, Cantor SB, Finnin MS, Livingston DM, Pavletich NP. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure Genes and Development. 16: 583-593. PMID 11877378 DOI: 10.1101/Gad.959202  0.484
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