| Year |
Citation |
Score |
| 2016 |
Solis E, Suyama JA, Lazenka MF, DeFelice LJ, Negus SS, Blough BE, Banks ML. Dissociable effects of the prodrug phendimetrazine and its metabolite phenmetrazine at dopamine transporters. Scientific Reports. 6: 31385. PMID 27514281 DOI: 10.1038/srep31385 |
0.365 |
|
| 2014 |
Fraser R, Chen Y, Guptaroy B, Luderman KD, Stokes SL, Beg A, DeFelice LJ, Gnegy ME. An N-terminal threonine mutation produces an efflux-favorable, sodium-primed conformation of the human dopamine transporter. Molecular Pharmacology. 86: 76-85. PMID 24753048 DOI: 10.1124/Mol.114.091926 |
0.398 |
|
| 2011 |
Henry LK, Iwamoto H, Field JR, Kaufmann K, Dawson ES, Jacobs MT, Adams C, Felts B, Zdravkovic I, Armstrong V, Combs S, Solis E, Rudnick G, Noskov SY, DeFelice LJ, et al. A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport. The Journal of Biological Chemistry. 286: 30823-36. PMID 21730057 DOI: 10.1074/Jbc.M111.250308 |
0.405 |
|
| 2008 |
Carvelli L, Blakely RD, DeFelice LJ. Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission. Proceedings of the National Academy of Sciences of the United States of America. 105: 14192-7. PMID 18768815 DOI: 10.1073/pnas.0802214105 |
0.409 |
|
| 2007 |
Blakely RD, DeFelice LJ. All aglow about presynaptic receptor regulation of neurotransmitter transporters. Molecular Pharmacology. 71: 1206-8. PMID 17329498 DOI: 10.1124/mol.107.035493 |
0.382 |
|
| 2007 |
DeFelice LJ, Goswami T. Transporters as channels. Annual Review of Physiology. 69: 87-112. PMID 17059369 DOI: 10.1146/annurev.physiol.69.031905.164816 |
0.467 |
|
| 2006 |
Schwartz JW, Piston D, DeFelice LJ. Molecular microfluorometry: converting arbitrary fluorescence units into absolute molecular concentrations to study binding kinetics and stoichiometry in transporters. Handbook of Experimental Pharmacology. 23-57. PMID 16722229 DOI: 10.1007/3-540-29784-7_2 |
0.529 |
|
| 2006 |
Henry LK, Defelice LJ, Blakely RD. Getting the message across: a recent transporter structure shows the way. Neuron. 49: 791-6. PMID 16543127 DOI: 10.1016/j.neuron.2006.03.002 |
0.368 |
|
| 2005 |
Blakely RD, Defelice LJ, Galli A. Biogenic amine neurotransmitter transporters: just when you thought you knew them. Physiology (Bethesda, Md.). 20: 225-31. PMID 16024510 DOI: 10.1152/Physiol.00013.2005 |
0.544 |
|
| 2005 |
Mason JN, Farmer H, Tomlinson ID, Schwartz JW, Savchenko V, DeFelice LJ, Rosenthal SJ, Blakely RD. Novel fluorescence-based approaches for the study of biogenic amine transporter localization, activity, and regulation. Journal of Neuroscience Methods. 143: 3-25. PMID 15763132 DOI: 10.1016/J.Jneumeth.2004.09.028 |
0.51 |
|
| 2005 |
Schwartz JW, Novarino G, Piston DW, DeFelice LJ. Substrate binding stoichiometry and kinetics of the norepinephrine transporter. The Journal of Biological Chemistry. 280: 19177-84. PMID 15757904 DOI: 10.1074/Jbc.M412923200 |
0.499 |
|
| 2004 |
Defelice LJ. Going against the flow. Nature. 432: 279. PMID 15549077 DOI: 10.1038/432279a |
0.431 |
|
| 2004 |
Carvelli L, McDonald PW, Blakely RD, Defelice LJ. Dopamine transporters depolarize neurons by a channel mechanism. Proceedings of the National Academy of Sciences of the United States of America. 101: 16046-51. PMID 15520385 DOI: 10.1073/pnas.0403299101 |
0.483 |
|
| 2004 |
DeFelice LJ. Transporter structure and mechanism. Trends in Neurosciences. 27: 352-9. PMID 15165740 DOI: 10.1016/j.tins.2004.04.007 |
0.44 |
|
| 2004 |
Xu H, Jin J, DeFelice LJ, Andrews NC, Clapham DE. A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway. Plos Biology. 2: E50. PMID 15024413 DOI: 10.1371/Journal.Pbio.0020050 |
0.517 |
|
| 2003 |
Adams SV, DeFelice LJ. Ionic currents in the human serotonin transporter reveal inconsistencies in the alternating access hypothesis. Biophysical Journal. 85: 1548-59. PMID 12944272 DOI: 10.1016/S0006-3495(03)74587-1 |
0.684 |
|
| 2003 |
Schwartz JW, Blakely RD, DeFelice LJ. Binding and transport in norepinephrine transporters. Real-time, spatially resolved analysis in single cells using a fluorescent substrate. The Journal of Biological Chemistry. 278: 9768-77. PMID 12499385 DOI: 10.1074/jbc.M209824200 |
0.524 |
|
| 2002 |
Adams SV, DeFelice LJ. Flux coupling in the human serotonin transporter. Biophysical Journal. 83: 3268-82. PMID 12496095 DOI: 10.1016/S0006-3495(02)75328-9 |
0.61 |
|
| 2002 |
Rosenthal SJ, Tomlinson I, Adkins EM, Schroeter S, Adams S, Swafford L, McBride J, Wang Y, DeFelice LJ, Blakely RD. Targeting cell surface receptors with ligand-conjugated nanocrystals. Journal of the American Chemical Society. 124: 4586-94. PMID 11971705 DOI: 10.1021/Ja003486S |
0.652 |
|
| 2002 |
Jayanthi LD, Vargas G, DeFelice LJ. Characterization of cocaine and antidepressant-sensitive norepinephrine transporters in rat placental trophoblasts. British Journal of Pharmacology. 135: 1927-34. PMID 11959795 DOI: 10.1038/sj.bjp.0704658 |
0.394 |
|
| 2002 |
Ramsey IS, DeFelice LJ. Serotonin transporter function and pharmacology are sensitive to expression level: evidence for an endogenous regulatory factor. The Journal of Biological Chemistry. 277: 14475-82. PMID 11844791 DOI: 10.1074/Jbc.M110783200 |
0.68 |
|
| 2001 |
DeFelice LJ, Adams SV, Ypey DL. Single-file diffusion and neurotransmitter transporters: Hodgkin and Keynes model revisited. Bio Systems. 62: 57-66. PMID 11595319 DOI: 10.1016/S0303-2647(01)00137-X |
0.669 |
|
| 2000 |
Jayanthi LD, Wilson JJ, Montalvo J, DeFelice LJ. Differential regulation of mammalian brain-specific proline transporter by calcium and calcium-dependent protein kinases. British Journal of Pharmacology. 129: 465-70. PMID 10711344 DOI: 10.1038/sj.bjp.0703071 |
0.316 |
|
| 1999 |
Galli A, Jayanthi LD, Ramsey IS, Miller JW, Fremeau RT, DeFelice LJ. L-proline and L-pipecolate induce enkephalin-sensitive currents in human embryonic kidney 293 cells transfected with the high-affinity mammalian brain L-proline transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 6290-7. PMID 10414958 DOI: 10.1523/Jneurosci.19-15-06290.1999 |
0.728 |
|
| 1999 |
Petersen CI, DeFelice LJ. Ionic interactions in the Drosophila serotonin transporter identify it as a serotonin channel. Nature Neuroscience. 2: 605-10. PMID 10404179 DOI: 10.1038/10158 |
0.39 |
|
| 1998 |
Apparsundaram S, Galli A, DeFelice LJ, Hartzell HC, Blakely RD. Acute regulation of norepinephrine transport: I. protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells. The Journal of Pharmacology and Experimental Therapeutics. 287: 733-43. PMID 9808704 |
0.506 |
|
| 1998 |
Galli A, Blakely RD, DeFelice LJ. Patch-clamp and amperometric recordings from norepinephrine transporters: channel activity and voltage-dependent uptake. Proceedings of the National Academy of Sciences of the United States of America. 95: 13260-5. PMID 9789076 DOI: 10.1073/Pnas.95.22.13260 |
0.622 |
|
| 1998 |
DeFelice LJ, Galli A. Fluctuation analysis of norepinephrine and serotonin transporter currents. Methods in Enzymology. 296: 578-93. PMID 9779475 DOI: 10.1016/S0076-6879(98)96041-4 |
0.631 |
|
| 1998 |
Blakely RD, Ramamoorthy S, Schroeter S, Qian Y, Apparsundaram S, Galli A, DeFelice LJ. Regulated phosphorylation and trafficking of antidepressant-sensitive serotonin transporter proteins. Biological Psychiatry. 44: 169-78. PMID 9693389 DOI: 10.1016/S0006-3223(98)00124-3 |
0.533 |
|
| 1998 |
DeFelice LJ, Galli A. Electrophysiological analysis of transporter function. Advances in Pharmacology (San Diego, Calif.). 42: 186-90. PMID 9327875 DOI: 10.1016/S1054-3589(08)60724-3 |
0.622 |
|
| 1997 |
Galli A, Petersen CI, deBlaquiere M, Blakely RD, DeFelice LJ. Drosophila serotonin transporters have voltage-dependent uptake coupled to a serotonin-gated ion channel. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 3401-11. PMID 9133366 DOI: 10.1523/Jneurosci.17-10-03401.1997 |
0.573 |
|
| 1997 |
Qian Y, Galli A, Ramamoorthy S, Risso S, DeFelice LJ, Blakely RD. Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 45-57. PMID 8987735 DOI: 10.1523/Jneurosci.17-01-00045.1997 |
0.537 |
|
| 1996 |
DeFelice LJ, Blakely RD. Pore models for transporters? Biophysical Journal. 70: 579-80. PMID 8789077 DOI: 10.1016/S0006-3495(96)79604-2 |
0.371 |
|
| 1996 |
Galli A, Blakely RD, DeFelice LJ. Norepinephrine transporters have channel modes of conduction. Proceedings of the National Academy of Sciences of the United States of America. 93: 8671-6. PMID 8710929 DOI: 10.1073/Pnas.93.16.8671 |
0.574 |
|
| 1996 |
Risso S, DeFelice LJ, Blakely RD. Sodium-dependent GABA-induced currents in GAT1-transfected HeLa cells. The Journal of Physiology. 490: 691-702. PMID 8683468 DOI: 10.1113/Jphysiol.1996.Sp021178 |
0.379 |
|
| 1996 |
Machaca K, DeFelice LJ, L'Hernault SW. A novel chloride channel localizes to Caenorhabditis elegans spermatids and chloride channel blockers induce spermatid differentiation. Developmental Biology. 176: 1-16. PMID 8654886 DOI: 10.1006/Dbio.1996.9999 |
0.425 |
|
| 1995 |
Galli A, DeFelice LJ, Duke BJ, Moore KR, Blakely RD. Sodium-dependent norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants. The Journal of Experimental Biology. 198: 2197-212. PMID 7500004 |
0.578 |
|
| 1995 |
DeFelice LJ. Review of Peracchia (Ed), Handbook of Membrane Channels Biophysical Journal. 68: 2207-2208. DOI: 10.1016/S0006-3495(95)80403-0 |
0.347 |
|
| 1994 |
DeFelice LJ. Forum: how does a zygote become an embryo? Zygote (Cambridge, England). 2: 179. PMID 8785674 DOI: 10.1017/S0967199400001957 |
0.306 |
|
| 1994 |
Galli A, DeFelice LJ. Inactivation of L-type Ca channels in embryonic chick ventricle cells: dependence on the cytoskeletal agents colchicine and taxol. Biophysical Journal. 67: 2296-304. PMID 7696470 DOI: 10.1016/S0006-3495(94)80715-5 |
0.567 |
|
| 1994 |
Dale B, DeFelice LJ, Kyozuka K, Santella L, Tosti E. Voltage clamp of the nuclear envelope Proceedings of the Royal Society B: Biological Sciences. 255: 119-124. DOI: 10.1098/Rspb.1994.0017 |
0.414 |
|
| 1993 |
Oleson DR, DeFelice LJ, Donahoe RM. A comparison of K+ channel characteristics in human T cells: perforated-patch versus whole-cell recording techniques. The Journal of Membrane Biology. 132: 229-41. PMID 8492307 DOI: 10.1007/BF00235740 |
0.375 |
|
| 1993 |
Mattioli M, Barboni B, DeFelice LJ. Calcium and potassium currents in porcine granulosa cells maintained in follicular or monolayer tissue culture. The Journal of Membrane Biology. 134: 75-83. PMID 8393490 DOI: 10.1007/BF00233477 |
0.33 |
|
| 1993 |
DeFelice LJ. Molecular and biophysical view of the Ca channel: a hypothesis regarding oligomeric structure, channel clustering, and macroscopic current. The Journal of Membrane Biology. 133: 191-202. PMID 8392582 DOI: 10.1007/BF00232019 |
0.366 |
|
| 1993 |
DeFelice LJ. Gating currents. Machinery behind the molecule. Biophysical Journal. 64: 5-6. PMID 8381682 DOI: 10.1016/S0006-3495(93)81333-X |
0.338 |
|
| 1993 |
Oleson DR, DeFelice LJ, Donahoe RM. Ethanol increases K+ conductance in human T-cells. Alcoholism, Clinical and Experimental Research. 17: 604-9. PMID 8333591 DOI: 10.1111/J.1530-0277.1993.Tb00807.X |
0.406 |
|
| 1993 |
Risso S, DeFelice LJ. Ca channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells. Biophysical Journal. 65: 1006-18. PMID 8241381 DOI: 10.1016/S0006-3495(93)81147-0 |
0.315 |
|
| 1993 |
Murnane JM, DeFelice LJ. Electrical maturation of the murine oocyte: an increase in calcium current coincides with acquisition of meiotic competence. Zygote (Cambridge, England). 1: 49-60. PMID 8081801 DOI: 10.1017/S0967199400001295 |
0.401 |
|
| 1993 |
Strassberg AF, DeFelice LJ. Limitations of the Hodgkin-Huxley formalism: effects of single channel kinetics on transmembrane voltage dynamics Neural Computation. 5: 843-855. DOI: 10.1162/Neco.1993.5.6.843 |
0.372 |
|
| 1993 |
DeFelice LJ, Isaac A. Chaotic states in a random world: Relationship between the nonlinear differential equations of excitability and the stochastic properties of ion channels Journal of Statistical Physics. 70: 339-354. DOI: 10.1007/BF01053972 |
0.374 |
|
| 1992 |
Liu YM, DeFelice LJ, Mazzanti M. Na channels that remain open throughout the cardiac action potential plateau. Biophysical Journal. 63: 654-62. PMID 1330034 DOI: 10.1016/S0006-3495(92)81635-1 |
0.613 |
|
| 1991 |
Mazzanti M, DeFelice LJ, Smith EF. Ion channels in murine nuclei during early development and in fully differentiated adult cells. The Journal of Membrane Biology. 121: 189-98. PMID 1715405 DOI: 10.1007/BF01870532 |
0.555 |
|
| 1991 |
Mazzanti M, DeFelice LJ, Liu YM. Gating of L-type Ca2+ channels in embryonic chick ventricle cells: dependence on voltage, current and channel density. The Journal of Physiology. 443: 307-34. PMID 1668339 DOI: 10.1113/Jphysiol.1991.Sp018835 |
0.623 |
|
| 1991 |
DeFelice LJ. Channels, carriers, and pumps: An introduction to membrane transport Cell. 66: 13-14. DOI: 10.1016/0092-8674(91)90133-J |
0.332 |
|
| 1990 |
DeFelice LJ, Goolsby WN, Mazzanti M. Potassium channels and the repolarization of cardiac cells. Annals of the New York Academy of Sciences. 588: 174-84. PMID 2357017 DOI: 10.1111/j.1749-6632.1990.tb13208.x |
0.616 |
|
| 1990 |
Mazzanti M, DeFelice LJ, Cohn J, Malter H. Ion channels in the nuclear envelope. Nature. 343: 764-7. PMID 2304551 DOI: 10.1038/343764a0 |
0.575 |
|
| 1990 |
Mazzanti M, DeFelice LJ. Ca channel gating during cardiac action potentials. Biophysical Journal. 58: 1059-65. PMID 2174270 DOI: 10.1016/S0006-3495(90)82448-6 |
0.588 |
|
| 1990 |
Mazzanti M, DeFelice LJ. Ca modulates outward current through IK1 channels. The Journal of Membrane Biology. 116: 41-5. PMID 2165175 DOI: 10.1007/BF01871670 |
0.603 |
|
| 1990 |
Wellis DP, DeFelice LJ, Mazzanti M. Outward sodium current in beating heart cells. Biophysical Journal. 57: 41-8. PMID 2153421 DOI: 10.1016/S0006-3495(90)82505-4 |
0.617 |
|
| 1988 |
Mazzanti M, DeFelice LJ. K channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells. Biophysical Journal. 54: 1139-48. PMID 3233269 DOI: 10.1016/S0006-3495(88)83048-0 |
0.567 |
|
| 1988 |
Kell MJ, DeFelice LJ. Surface charge near the cardiac inward-rectifier channel measured from single-channel conductance. The Journal of Membrane Biology. 102: 1-10. PMID 2456392 DOI: 10.1007/BF01875348 |
0.405 |
|
| 1987 |
DeFelice LJ, Kell MJ. Sperm-activated currents in ascidian oocytes. Developmental Biology. 119: 123-8. PMID 3792625 DOI: 10.1016/0012-1606(87)90213-2 |
0.421 |
|
| 1987 |
Mazzanti M, DeFelice LJ. Na channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells. Biophysical Journal. 52: 95-100. PMID 2440494 DOI: 10.1016/S0006-3495(87)83192-2 |
0.632 |
|
| 1987 |
Mazzanti M, DeFelice LJ. Regulation of the Na-conducting Ca channel during the cardiac action potential. Biophysical Journal. 51: 115-21. PMID 2432951 DOI: 10.1016/S0006-3495(87)83316-7 |
0.6 |
|
| 1986 |
Levi R, DeFelice LJ. Sodium-conducting channels in cardiac membranes in low calcium. Biophysical Journal. 50: 5-9. PMID 2425858 DOI: 10.1016/S0006-3495(86)83433-6 |
0.347 |
|
| 1984 |
Clapham DE, Defelice LJ. Voltage-activated k channels in embryonic chick heart. Biophysical Journal. 45: 40-2. PMID 19431556 DOI: 10.1016/S0006-3495(84)84099-0 |
0.546 |
|
| 1984 |
Fischmeister R, DeFelice LJ, Ayer RK, Levi R, DeHaan RL. Channel currents during spontaneous action potentials in embryonic chick heart cells. The action potential patch clamp. Biophysical Journal. 46: 267-71. PMID 6089925 DOI: 10.1016/S0006-3495(84)84020-5 |
0.625 |
|
| 1983 |
Clay JR, DeFelice LJ. Relationship between membrane excitability and single channel open-close kinetics. Biophysical Journal. 42: 151-7. PMID 6305436 DOI: 10.1016/S0006-3495(83)84381-1 |
0.308 |
|
| 1982 |
Clapham DE, DeFelice LJ. Small signal impedance of heart cell membranes. The Journal of Membrane Biology. 67: 63-71. PMID 7097756 DOI: 10.1007/BF01868648 |
0.542 |
|
| 1979 |
Clay JR, DeFelice LJ, DeHaan RL. Current noise parameters derived from voltage noise and impedance in embryonic heart cell aggregates. Biophysical Journal. 28: 169-84. PMID 262547 DOI: 10.1016/S0006-3495(79)85169-3 |
0.61 |
|
| 1977 |
DeFelice LJ, Alkon DL. Voltage noise from hair cells during mechanical stimulation. Nature. 269: 613-5. PMID 917109 DOI: 10.1038/269613a0 |
0.304 |
|
| 1977 |
DeFelice LJ. Fluctuation analysis in neurobiology. International Review of Neurobiology. 20: 169-208. PMID 304052 DOI: 10.1016/S0074-7742(08)60653-4 |
0.324 |
|
| 1977 |
DeFelice LJ, DeHaan RL. Membrane noise and intercellular communication Proceedings of the Ieee. 65: 796-799. DOI: 10.1109/PROC.1977.10562 |
0.496 |
|
| 1975 |
DeFelice LJ, DeHaan RL. Voltage noise and impedance from heart cell aggregates Biophysical Journal. 15: 130A. |
0.535 |
|
| 1974 |
Wanke E, DeFelice LJ, Conti F. Voltage noise, current noise and impedance in space clamped squid giant axon. Pflã¼Gers Archiv : European Journal of Physiology. 347: 63-74. PMID 4407444 DOI: 10.1007/BF00587055 |
0.354 |
|
| 1972 |
Defelice LJ, Michalides JP. Electrical noise from synthetic membranes. The Journal of Membrane Biology. 9: 261-90. PMID 24177652 DOI: 10.1007/BF01868056 |
0.307 |
|
| 1971 |
DeFelice LJ, Firth DR. Spontaneous voltage fluctuations in glass microelectrodes. Ieee Transactions On Bio-Medical Engineering. 18: 339-51. PMID 5564366 DOI: 10.1109/TBME.1971.4502865 |
0.67 |
|
| 1971 |
Firth DR, DeFelice LJ. Electrical resistance and volume flow in glass microelectrodes. Canadian Journal of Physiology and Pharmacology. 49: 436-47. PMID 5120271 |
0.621 |
|
| 1969 |
DeFelice LJ, Challice CE. Anatomical and ultrastructural study of the electrophysiological atrioventricular node of the rabbit. Circulation Research. 24: 457-74. PMID 5766521 DOI: 10.1161/01.Res.24.3.457 |
0.535 |
|
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