Esa R. Korpi, M.D, Ph.D. - Publications

Affiliations: 
Department of Pharmacology University of Helsinki, Helsingfors, Finland 

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nagaeva E, Schäfer A, Linden AM, Elsilä LV, Egorova K, Umemori J, Ryazantseva M, Korpi ER. Somatostatin-expressing neurons in the ventral tegmental area innervate specific forebrain regions and are involved in stress response. Eneuro. PMID 37553240 DOI: 10.1523/ENEURO.0149-23.2023  0.777
2023 Moliner R, Girych M, Brunello CA, Kovaleva V, Biojone C, Enkavi G, Antenucci L, Kot EF, Goncharuk SA, Kaurinkoski K, Kuutti M, Fred SM, Elsilä LV, Sakson S, Cannarozzo C, ... ... Korpi ER, et al. Psychedelics promote plasticity by directly binding to BDNF receptor TrkB. Nature Neuroscience. 26: 1032-1041. PMID 37280397 DOI: 10.1038/s41593-023-01316-5  0.776
2023 Frankenhaeuser F, Söder B, Källmén H, Korpi ER, Meurman JH. Periodontitis may predict the use of prescription medicines later in life, a database study. Frontiers in Pharmacology. 14: 1146475. PMID 36992840 DOI: 10.3389/fphar.2023.1146475  0.223
2022 Elsilä LV, Harkki J, Enberg E, Martti A, Linden AM, Korpi ER. Effects of acute lysergic acid diethylamide on intermittent ethanol and sucrose drinking and intracranial self-stimulation in C57BL/6 mice. Journal of Psychopharmacology (Oxford, England). 36: 860-874. PMID 35695174 DOI: 10.1177/02698811221104641  0.785
2021 Nagaeva E, Zubarev I, Korpi ER. Electrophysiological Properties of Neurons: Current-Clamp Recordings in Mouse Brain Slices and Firing-Pattern Analysis. Bio-Protocol. 11: e4061. PMID 34263004 DOI: 10.21769/BioProtoc.4061  0.793
2021 Grotell M, Abdurakhmanova S, Elsilä LV, Korpi ER. Mice Lacking GABA Receptor Subunit Have Altered Pharmaco-EEG Responses to Multiple Drugs. Frontiers in Pharmacology. 12: 706894. PMID 34234684 DOI: 10.3389/fphar.2021.706894  0.816
2021 Grotell M, den Hollander B, Jalkanen A, Törrönen E, Ihalainen J, de Miguel E, Dudek M, Kettunen MI, Hyytiä P, Forsberg MM, Kankuri E, Korpi ER. Alcohol Co-Administration Changes Mephedrone-Induced Alterations of Neuronal Activity. Frontiers in Pharmacology. 12: 679759. PMID 33995109 DOI: 10.3389/fphar.2021.679759  0.78
2020 Elsilä LV, Korhonen N, Hyytiä P, Korpi ER. Acute Lysergic Acid Diethylamide Does Not Influence Reward-Driven Decision Making of C57BL/6 Mice in the Iowa Gambling Task. Frontiers in Pharmacology. 11: 602770. PMID 33343373 DOI: 10.3389/fphar.2020.602770  0.791
2020 Nagaeva E, Zubarev I, Bengtsson Gonzales C, Forss M, Nikouei K, Miguel E, Elsilä L, Linden AM, Hjerling-Leffler J, Augustine GJ, Korpi ER. Heterogeneous somatostatin-expressing neuron population in mouse ventral tegmental area. Elife. 9. PMID 32749220 DOI: 10.7554/Elife.59328  0.779
2020 Abdurakhmanova S, Grotell M, Kauhanen J, Linden AM, Korpi ER, Panula P. Increased Sensitivity of Mice Lacking Extrasynaptic δ-Containing GABA Receptors to Histamine Receptor 3 Antagonists. Frontiers in Pharmacology. 11: 594. PMID 32435195 DOI: 10.3389/fphar.2020.00594  0.827
2020 Korpi ER, Lindholm D, Panula P, Tienari PJ, Haltia M. Finnish neuroscience from past to present European Journal of Neuroscience. PMID 32017266 DOI: 10.1111/Ejn.14693  0.19
2019 de Miguel E, Vekovischeva O, Elsilä LV, Panhelainen A, Kankuri E, Aitta-Aho T, Korpi ER. Conditioned Aversion and Neuroplasticity Induced by a Superagonist of Extrasynaptic GABA Receptors: Correlation With Activation of the Oval BNST Neurons and CRF Mechanisms. Frontiers in Molecular Neuroscience. 12: 130. PMID 31178693 DOI: 10.3389/fnmol.2019.00130  0.827
2019 Aitta-Aho T, Maksimovic M, Dahl K, Sprengel R, Korpi ER. Attenuation of Novelty-Induced Hyperactivity of Mice by Cannabidiol and Hippocampal Inhibitory Chemogenetics. Frontiers in Pharmacology. 10: 309. PMID 30984001 DOI: 10.3389/Fphar.2019.00309  0.825
2019 Mansikkamäki S, Sinkkonen ST, Korpi ER, Lüddens H. Multiple actions of fenamates and other nonsteroidal anti-inflammatory drugs on GABA receptors. European Journal of Pharmacology. 853: 247-255. PMID 30930251 DOI: 10.1016/j.ejphar.2019.03.039  0.741
2019 Leggio GM, Di Marco R, Gulisano W, D'Ascenzo M, Torrisi SA, Geraci F, Lavanco G, Dahl K, Giurdanella G, Castorina A, Aitta-Aho T, Aceto G, Bucolo C, Puzzo D, Grassi C, ... Korpi ER, et al. Dopaminergic-GABAergic interplay and alcohol binge drinking. Pharmacological Research. 141: 384-391. PMID 30648615 DOI: 10.1016/j.phrs.2019.01.022  0.825
2019 Korpi ER, Mäkelä R, Uusi-Oukari M. Ethanol: Novel Actions on Nerve Cell Physiology Explain Impaired Functions. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 13: 164-170. PMID 11390783 DOI: 10.1152/physiologyonline.1998.13.4.164  0.787
2018 de Miguel E, Vekovischeva O, Kuokkanen K, Vesajoki M, Paasikoski N, Kaskinoro J, Myllymäki M, Lainiola M, Janhunen SK, Hyytiä P, Linden AM, Korpi ER. GABA receptor positive allosteric modulators with different efficacies affect neuroadaptation to and self-administration of alcohol and cocaine. Addiction Biology. PMID 30421860 DOI: 10.1111/adb.12688  0.838
2018 Kiiskinen T, Korpi ER, Aitta-Aho T. Normal extinction and reinstatement of morphine-induced conditioned place preference in the GluA1-KO mouse line. Behavioural Pharmacology. PMID 30376459 DOI: 10.1097/FBP.0000000000000449  0.817
2018 Siivonen MS, de Miguel E, Aaltio J, Manner AK, Vahermo M, Yli-Kauhaluoma J, Linden AM, Aitta-Aho T, Korpi ER. Conditioned Reward of Opioids, but not Psychostimulants, is Impaired in GABA Receptor δ Subunit Knockout Mice. Basic & Clinical Pharmacology & Toxicology. PMID 29781560 DOI: 10.1111/Bcpt.13043  0.832
2017 Vashchinkina E, Piippo O, Vekovischeva O, Krupitsky E, Ilyuk R, Neznanov N, Kazankov K, Zaplatkin I, Korpi ER. Addiction-related interactions of pregabalin with morphine in mice and humans: reinforcing and inhibiting effects. Addiction Biology. PMID 28741741 DOI: 10.1111/adb.12538  0.345
2017 Korpi ER, Linden AM, Hytönen HR, Paasikoski N, Vashchinkina E, Dudek M, Herr DR, Hyytiä P. Continuous delivery of naltrexone and nalmefene leads to tolerance in reducing alcohol drinking and to supersensitivity of brain opioid receptors. Addiction Biology. 22: 1022-1035. PMID 26990998 DOI: 10.1111/adb.12393  0.354
2016 Leppä E, Linden AM, Aller MI, Wulff P, Vekovischeva O, Luscher B, Lüddens H, Wisden W, Korpi ER. Increased Motor-Impairing Effects of the Neuroactive Steroid Pregnanolone in Mice with Targeted Inactivation of the GABAA Receptor γ2 Subunit in the Cerebellum. Frontiers in Pharmacology. 7: 403. PMID 27833556 DOI: 10.3389/Fphar.2016.00403  0.839
2016 Oja SS, Saransaari P, Korpi ER. Neurotoxicity of Ammonia. Neurochemical Research. 42: 713-720. PMID 27465396 DOI: 10.1007/s11064-016-2014-x  0.64
2015 den Hollander B, Sundström M, Pelander A, Siltanen A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E. Mitochondrial respiratory dysfunction due to the conversion of substituted cathinones to methylbenzamides in SH-SY5Y cells. Scientific Reports. 5: 14924. PMID 26462443 DOI: 10.1038/srep14924  0.781
2015 Korpi ER, den Hollander B, Farooq U, Vashchinkina E, Rajkumar R, Nutt DJ, Hyytiä P, Dawe GS. Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse. Pharmacological Reviews. 67: 872-1004. PMID 26403687 DOI: 10.1124/Pr.115.010967  0.802
2014 Bhandage AK, Jin Z, Bazov I, Kononenko O, Bakalkin G, Korpi ER, Birnir B. GABA-A and NMDA receptor subunit mRNA expression is altered in the caudate but not the putamen of the postmortem brains of alcoholics. Frontiers in Cellular Neuroscience. 8: 415. PMID 25538565 DOI: 10.3389/fncel.2014.00415  0.443
2014 den Hollander B, Dudek M, Ojanperä I, Kankuri E, Hyytiä P, Korpi ER. Manganese-enhanced magnetic resonance imaging reveals differential long-term neuroadaptation after methamphetamine and the substituted cathinone 4-methylmethcathinone (mephedrone). The International Journal of Neuropsychopharmacology. 18. PMID 25522432 DOI: 10.1093/ijnp/pyu106  0.787
2014 Vashchinkina E, Panhelainen A, Aitta-Aho T, Korpi ER. GABAA receptor drugs and neuronal plasticity in reward and aversion: focus on the ventral tegmental area. Frontiers in Pharmacology. 5: 256. PMID 25505414 DOI: 10.3389/fphar.2014.00256  0.835
2014 Maksimovic M, Aitta-aho T, Korpi ER. Reversal of novelty-induced hippocampal c-Fos expression in GluA1 subunit-deficient mice by chronic treatment targeting glutamatergic transmission. European Journal of Pharmacology. 745: 36-45. PMID 25446922 DOI: 10.1016/j.ejphar.2014.10.005  0.816
2014 Jin Z, Bhandage AK, Bazov I, Kononenko O, Bakalkin G, Korpi ER, Birnir B. Expression of specific ionotropic glutamate and GABA-A receptor subunits is decreased in central amygdala of alcoholics. Frontiers in Cellular Neuroscience. 8: 288. PMID 25278838 DOI: 10.3389/fncel.2014.00288  0.42
2014 Maksimovic M, Vekovischeva OY, Aitta-aho T, Korpi ER. Chronic treatment with mood-stabilizers attenuates abnormal hyperlocomotion of GluA1-subunit deficient mice. Plos One. 9: e100188. PMID 24932798 DOI: 10.1371/journal.pone.0100188  0.808
2014 den Hollander B, Sundström M, Pelander A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E. Keto amphetamine toxicity-focus on the redox reactivity of the cathinone designer drug mephedrone. Toxicological Sciences : An Official Journal of the Society of Toxicology. 141: 120-31. PMID 24913801 DOI: 10.1093/toxsci/kfu108  0.768
2014 Joensuu T, Tegelberg S, Reinmaa E, SegerstrÃ¥le M, Hakala P, Pehkonen H, Korpi ER, Tyynelä J, Taira T, Hovatta I, Kopra O, Lehesjoki AE. Gene expression alterations in the cerebellum and granule neurons of Cstb(-/-) mouse are associated with early synaptic changes and inflammation. Plos One. 9: e89321. PMID 24586687 DOI: 10.1371/Journal.Pone.0089321  0.377
2014 Jin Z, Bhandage AK, Bazov I, Kononenko O, Bakalkin G, Korpi ER, Birnir B. Selective increases of AMPA, NMDA, and kainate receptor subunit mRNAs in the hippocampus and orbitofrontal cortex but not in prefrontal cortex of human alcoholics. Frontiers in Cellular Neuroscience. 8: 11. PMID 24523671 DOI: 10.3389/fncel.2014.00011  0.428
2013 Vashchinkina E, Manner AK, Vekovischeva O, den Hollander B, Uusi-Oukari M, Aitta-Aho T, Korpi ER. Neurosteroid Agonist at GABAA receptor induces persistent neuroplasticity in VTA dopamine neurons. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 727-37. PMID 24077066 DOI: 10.1038/npp.2013.258  0.845
2012 Semenov A, Möykkynen T, Coleman SK, Korpi ER, Keinänen K. Autoinactivation of the stargazin-AMPA receptor complex: subunit-dependency and independence from physical dissociation. Plos One. 7: e49282. PMID 23166629 DOI: 10.1371/journal.pone.0049282  0.785
2012 den Hollander B, Rozov S, Linden AM, Uusi-Oukari M, Ojanperä I, Korpi ER. Long-term cognitive and neurochemical effects of "bath salt" designer drugs methylone and mephedrone. Pharmacology, Biochemistry, and Behavior. 103: 501-9. PMID 23099177 DOI: 10.1016/j.pbb.2012.10.006  0.785
2012 Aitta-aho T, Möykkynen TP, Panhelainen AE, Vekovischeva OY, Bäckström P, Korpi ER. Importance of GluA1 subunit-containing AMPA glutamate receptors for morphine state-dependency. Plos One. 7: e38325. PMID 22675452 DOI: 10.1371/journal.pone.0038325  0.815
2012 Vashchinkina E, Panhelainen A, Vekovischeva OY, Aitta-aho T, Ebert B, Ator NA, Korpi ER. GABA site agonist gaboxadol induces addiction-predicting persistent changes in ventral tegmental area dopamine neurons but is not rewarding in mice or baboons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5310-20. PMID 22496576 DOI: 10.1523/JNEUROSCI.4697-11.2012  0.857
2012 Möykkynen T, Korpi ER. Acute effects of ethanol on glutamate receptors. Basic & Clinical Pharmacology & Toxicology. 111: 4-13. PMID 22429661 DOI: 10.1111/j.1742-7843.2012.00879.x  0.778
2012 Jin Z, Bazov I, Kononenko O, Korpi ER, Bakalkin G, Birnir B. Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics. Frontiers in Cellular Neuroscience. 5: 30. PMID 22319468 DOI: 10.3389/fncel.2011.00030  0.356
2011 Panhelainen AE, Korpi ER. Evidence for a role of inhibition of orexinergic neurons in the anxiolytic and sedative effects of diazepam: A c-Fos study. Pharmacology, Biochemistry, and Behavior. 101: 115-24. PMID 22210490 DOI: 10.1016/j.pbb.2011.12.011  0.805
2011 Tacke U, den Hollander B, Simojoki K, Korpi ER, Pihlainen K, Alho H. [Designer drugs in Finland]. Duodecim; Laaketieteellinen Aikakauskirja. 127: 2027-36. PMID 22073534  0.773
2011 Leppä E, Linden AM, Vekovischeva OY, Swinny JD, Rantanen V, Toppila E, Höger H, Sieghart W, Wulff P, Wisden W, Korpi ER. Removal of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations. Plos One. 6: e24159. PMID 21912668 DOI: 10.1371/Journal.Pone.0024159  0.847
2011 Leppä E, Linden AM, Rabe H, Vekovischeva OY, Wulff P, Lüddens H, Wisden W, Korpi ER. Actions of two GABAA receptor benzodiazepine-site ligands that are mediated via non-γ2-dependent modulation. European Journal of Pharmacology. 666: 111-21. PMID 21616065 DOI: 10.1016/J.Ejphar.2011.05.011  0.839
2011 Linden AM, Schmitt U, Leppä E, Wulff P, Wisden W, Lüddens H, Korpi ER. Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through αβγ2-type GABA(A) Receptors. Frontiers in Neuroscience. 5: 3. PMID 21270945 DOI: 10.3389/Fnins.2011.00003  0.823
2011 Procaccini C, Aitta-aho T, Jaako-Movits K, Zharkovsky A, Panhelainen A, Sprengel R, Linden AM, Korpi ER. Excessive novelty-induced c-Fos expression and altered neurogenesis in the hippocampus of GluA1 knockout mice. The European Journal of Neuroscience. 33: 161-74. PMID 21073553 DOI: 10.1111/J.1460-9568.2010.07485.X  0.828
2010 Tajima N, Itokazu Y, Korpi ER, Somerharju P, Käkelä R. Activity of BK(Ca) channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells. The Journal of Biological Chemistry. 286: 5624-38. PMID 21135099 DOI: 10.1074/jbc.M110.149898  0.214
2010 Coleman SK, Möykkynen T, Hinkkuri S, Vaahtera L, Korpi ER, Pentikäinen OT, Keinänen K. Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors. The Journal of Biological Chemistry. 285: 36032-9. PMID 20837486 DOI: 10.1074/jbc.M110.156943  0.781
2010 Hellsten KS, Sinkkonen ST, Hyde TM, Kleinman JE, Särkioja T, Maksimow A, Uusi-Oukari M, Korpi ER. Human locus coeruleus neurons express the GABA(A) receptor gamma2 subunit gene and produce benzodiazepine binding. Neuroscience Letters. 477: 77-81. PMID 20417252 DOI: 10.1016/j.neulet.2010.04.035  0.822
2010 Uusi-Oukari M, Korpi ER. Regulation of GABA(A) receptor subunit expression by pharmacological agents. Pharmacological Reviews. 62: 97-135. PMID 20123953 DOI: 10.1124/pr.109.002063  0.847
2010 Coleman SK, Cai C, Kalkkinen N, Korpi ER, Keinänen K. Analysis of the potential role of GluA4 carboxyl-terminus in PDZ interactions. Plos One. 5: e8715. PMID 20090852 DOI: 10.1371/journal.pone.0008715  0.351
2010 Chandra D, Halonen LM, Linden AM, Procaccini C, Hellsten K, Homanics GE, Korpi ER. Prototypic GABA(A) receptor agonist muscimol acts preferentially through forebrain high-affinity binding sites. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 999-1007. PMID 20032968 DOI: 10.1038/Npp.2009.203  0.824
2010 Nuutinen S, Karlstedt K, Aitta-Aho T, Korpi ER, Panula P. Histamine and H3 receptor-dependent mechanisms regulate ethanol stimulation and conditioned place preference in mice. Psychopharmacology. 208: 75-86. PMID 19911169 DOI: 10.1007/s00213-009-1710-5  0.825
2009 Marinkovic I, Strbian D, Pedrono E, Vekovischeva OY, Shekhar S, Durukan A, Korpi ER, Abo-Ramadan U, Tatlisumak T. Decompressive craniectomy for intracerebral hemorrhage. Neurosurgery. 65: 780-6, 1 p following. PMID 19834384 DOI: 10.1227/01.NEU.0000351775.30702.A9  0.216
2009 Möykkynen TP, Coleman SK, Keinänen K, Lovinger DM, Korpi ER. Ethanol increases desensitization of recombinant GluR-D AMPA receptor and TARP combinations. Alcohol (Fayetteville, N.Y.). 43: 277-84. PMID 19560629 DOI: 10.1016/j.alcohol.2009.04.005  0.777
2009 Halonen LM, Sinkkonen ST, Chandra D, Homanics GE, Korpi ER. Brain regional distribution of GABA(A) receptors exhibiting atypical GABA agonism: roles of receptor subunits. Neurochemistry International. 55: 389-96. PMID 19397945 DOI: 10.1016/J.Neuint.2009.04.008  0.75
2009 Coleman SK, Möykkynen T, Jouppila A, Koskelainen S, Rivera C, Korpi ER, Keinänen K. Agonist occupancy is essential for forward trafficking of AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 303-12. PMID 19144831 DOI: 10.1523/JNEUROSCI.3953-08.2009  0.79
2009 Ingman K, Honkanen A, Hyytiä P, Huttunen MO, Korpi ER. Risperidone reduces limited access alcohol drinking in alcohol-preferring rats. European Journal of Pharmacology. 468: 121-7. PMID 12742519 DOI: 10.1016/s0014-2999(03)01669-8  0.332
2008 Aitta-Aho T, Vekovischeva OY, Neuvonen PJ, Korpi ER. Reduced benzodiazepine tolerance, but increased flumazenil-precipitated withdrawal in AMPA-receptor GluR-A subunit-deficient mice. Pharmacology, Biochemistry, and Behavior. 92: 283-90. PMID 19141300 DOI: 10.1016/j.pbb.2008.12.015  0.824
2008 Linden AM, Aller MI, Leppä E, Rosenberg PH, Wisden W, Korpi ER. K+ channel TASK-1 knockout mice show enhanced sensitivities to ataxic and hypnotic effects of GABA(A) receptor ligands. The Journal of Pharmacology and Experimental Therapeutics. 327: 277-86. PMID 18660435 DOI: 10.1124/Jpet.108.142083  0.834
2008 Heikkinen AE, Möykkynen TP, Korpi ER. Long-lasting modulation of glutamatergic transmission in VTA dopamine neurons after a single dose of benzodiazepine agonists. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 290-8. PMID 18563060 DOI: 10.1038/npp.2008.89  0.819
2008 Vihavainen T, Piltonen M, Tuominen RK, Korpi ER, Ahtee L. Morphine-nicotine interaction in conditioned place preference in mice after chronic nicotine exposure. European Journal of Pharmacology. 587: 169-74. PMID 18466896 DOI: 10.1016/j.ejphar.2008.03.028  0.408
2008 Salmi E, Laitio RM, Aalto S, Maksimow AT, Långsjö JW, Kaisti KK, Aantaa R, Oikonen V, Metsähonkala L, Någren K, Korpi ER, Scheinin H. Xenon does not affect gamma-aminobutyric acid type A receptor binding in humans. Anesthesia and Analgesia. 106: 129-34, table of con. PMID 18165567 DOI: 10.1213/01.ane.0000287658.14763.13  0.441
2008 Korpi ER. [Not Available]. Duodecim; Laaketieteellinen Aikakauskirja. 122: 2559-61. PMID 17233332  0.189
2007 Birnir B, Korpi ER. The impact of sub-cellular location and intracellular neuronal proteins on properties of GABAA receptors Current Pharmaceutical Design. 13: 3169-3177. PMID 18045166 DOI: 10.2174/138161207782341330  0.398
2007 Saarelainen KS, Ranna M, Rabe H, Sinkkonen ST, Möykkynen T, Uusi-Oukari M, Linden AM, Lüddens H, Korpi ER. Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors. Journal of Neurochemistry. 105: 338-50. PMID 18021290 DOI: 10.1111/j.1471-4159.2007.05136.x  0.843
2007 Linden AM, Sandu C, Aller MI, Vekovischeva OY, Rosenberg PH, Wisden W, Korpi ER. TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics. The Journal of Pharmacology and Experimental Therapeutics. 323: 924-34. PMID 17875609 DOI: 10.1124/Jpet.107.129544  0.646
2007 Korpi ER, Debus F, Linden AM, Malécot C, Leppä E, Vekovischeva O, Rabe H, Böhme I, Aller MI, Wisden W, Lüddens H. Does ethanol act preferentially via selected brain GABAA receptor subtypes? the current evidence is ambiguous. Alcohol (Fayetteville, N.Y.). 41: 163-76. PMID 17591542 DOI: 10.1016/J.Alcohol.2007.03.007  0.837
2007 Wulff P, Goetz T, Leppä E, Linden AM, Renzi M, Swinny JD, Vekovischeva OY, Sieghart W, Somogyi P, Korpi ER, Farrant M, Wisden W. From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors. Nature Neuroscience. 10: 923-9. PMID 17572671 DOI: 10.1515/Nf-2007-0405  0.838
2007 Sarviharju M, Hyytiä P, Hervonen A, Jaatinen P, Kiianmaa K, Korpi ER. Lifelong ethanol consumption and brain regional GABAA receptor subunit mRNA expression in alcohol-preferring rats. Alcohol (Fayetteville, N.Y.). 40: 159-66. PMID 17418695 DOI: 10.1016/j.alcohol.2006.11.003  0.388
2007 Möykkynen TP, Sinkkonen ST, Korpi ER. Compensation by reduced L-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor responses in a mouse model with reduced gamma-aminobutyric acid type A receptor-mediated synaptic inhibition. Journal of Neuroscience Research. 85: 668-72. PMID 17131399 DOI: 10.1002/jnr.21138  0.839
2006 Coleman SK, Möykkynen T, Cai C, von Ossowski L, Kuismanen E, Korpi ER, Keinänen K. Isoform-specific early trafficking of AMPA receptor flip and flop variants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11220-9. PMID 17065461 DOI: 10.1523/JNEUROSCI.2301-06.2006  0.776
2006 Lemberg KK, Kontinen VK, Siiskonen AO, Viljakka KM, Yli-Kauhaluoma JT, Korpi ER, Kalso EA. Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats. Anesthesiology. 105: 801-12. PMID 17006080  0.243
2006 Ingman K, Kupila J, Hyytiä P, Korpi ER. Effects of aripiprazole on alcohol intake in an animal model of high-alcohol drinking. Alcohol and Alcoholism (Oxford, Oxfordshire). 41: 391-8. PMID 16684847 DOI: 10.1093/alcalc/agl037  0.271
2006 Salonen V, Kallinen S, Lopez-Picon FR, Korpi ER, Holopainen IE, Uusi-Oukari M. AMPA/kainate receptor-mediated up-regulation of GABAA receptor delta subunit mRNA expression in cultured rat cerebellar granule cells is dependent on NMDA receptor activation. Brain Research. 1087: 33-40. PMID 16626639 DOI: 10.1016/j.brainres.2006.02.104  0.828
2006 Ingman K, Korpi ER. Alcohol drinking of alcohol-preferring AA rats is differentially affected by clozapine and olanzapine. European Journal of Pharmacology. 534: 133-40. PMID 16480711 DOI: 10.1016/j.ejphar.2006.01.024  0.26
2006 Ranna M, Sinkkonen ST, Möykkynen T, Uusi-Oukari M, Korpi ER. Impact of epsilon and theta subunits on pharmacological properties of alpha3beta1 GABAA receptors expressed in Xenopus oocytes. Bmc Pharmacology. 6: 1. PMID 16412217 DOI: 10.1186/1471-2210-6-1  0.825
2006 Linden AM, Aller MI, Leppä E, Vekovischeva O, Aitta-Aho T, Veale EL, Mathie A, Rosenberg P, Wisden W, Korpi ER. The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists. The Journal of Pharmacology and Experimental Therapeutics. 317: 615-26. PMID 16397088 DOI: 10.1124/Jpet.105.098525  0.797
2006 Sinkkonen ST, Rabe H, Lüddens H, Korpi ER. Evidence for a reduction of coupling between GABAA receptor agonist and ionophore binding sites by inorganic phosphate. Neurochemical Research. 30: 1471-82. PMID 16362766 DOI: 10.1007/s11064-005-8824-x  0.725
2005 Pasantes-Morales H, Korpi ER. Simo S. Oja--amino acids all along as building blocks of brain and life. Neurochemical Research. 30: 1463-4. PMID 16362764 DOI: 10.1007/s11064-005-8822-z  0.252
2005 Aller MI, Veale EL, Linden AM, Sandu C, Schwaninger M, Evans LJ, Korpi ER, Mathie A, Wisden W, Brickley SG. Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11455-67. PMID 16339039 DOI: 10.1523/Jneurosci.3153-05.2005  0.574
2005 Salmi E, Långsjö JW, Aalto S, Någren K, Metsähonkala L, Kaisti KK, Korpi ER, Hietala J, Scheinin H. Subanesthetic ketamine does not affect 11C-flumazenil binding in humans. Anesthesia and Analgesia. 101: 722-725. PMID 16115981 DOI: 10.1213/01.ANE.0000156951.83242.8D  0.443
2005 Möykkynen T, Liebkind R, Sjöberg J, Korpi ER, Liesi P. The neuroprotective KDI domain of gamma 1-laminin is a universal and potent inhibitor of ionotropic glutamate receptors. Journal of Neuroscience Research. 81: 797-804. PMID 16044429 DOI: 10.1002/jnr.20523  0.784
2005 Pakkanen JS, Nousiainen H, Yli-Kauhaluoma J, Kylänlahti I, Möykkynen T, Korpi ER, Peng JH, Lukas RJ, Ahtee L, Tuominen RK. Methadone increases intracellular calcium in SH-SY5Y and SH-EP1-halpha7 cells by activating neuronal nicotinic acetylcholine receptors. Journal of Neurochemistry. 94: 1329-41. PMID 16000156 DOI: 10.1111/J.1471-4159.2005.03279.X  0.39
2005 Korpi ER, Sinkkonen ST. GABA(A) receptor subtypes as targets for neuropsychiatric drug development. Pharmacology & Therapeutics. 109: 12-32. PMID 15996746 DOI: 10.1016/j.pharmthera.2005.05.009  0.747
2005 Juhila J, Honkanen A, Sallinen J, Haapalinna A, Korpi ER, Scheinin M. alpha(2A)-Adrenoceptors regulate d-amphetamine-induced hyperactivity and behavioural sensitization in mice. European Journal of Pharmacology. 517: 74-83. PMID 15978573 DOI: 10.1016/J.EJPHAR.2005.05.022  0.387
2005 Chandra D, Korpi ER, Miralles CP, De Blas AL, Homanics GE. GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines. Bmc Neuroscience. 6: 30. PMID 15850489 DOI: 10.1186/1471-2202-6-30  0.488
2005 Sonner JM, Cascio M, Xing Y, Fanselow MS, Kralic JE, Morrow AL, Korpi ER, Hardy S, Sloat B, Eger EI, Homanics GE. Alpha 1 subunit-containing GABA type A receptors in forebrain contribute to the effect of inhaled anesthetics on conditioned fear. Molecular Pharmacology. 68: 61-8. PMID 15833735 DOI: 10.1124/Mol.104.009936  0.463
2005 Lindroos MM, Soini SL, Kukko‐Lukjanov T, Korpi ER, Lovinger D, Holopainen IE. Maturation of cultured hippocampal slices results in increased excitability in granule cells International Journal of Developmental Neuroscience. 23: 65-73. PMID 15730888 DOI: 10.1016/J.Ijdevneu.2004.08.003  0.311
2004 Salmi E, Kaisti KK, Metsähonkala L, Oikonen V, Aalto S, Någren K, Hinkka S, Hietala J, Korpi ER, Scheinin H. Sevoflurane and propofol increase 11C-flumazenil binding to gamma-aminobutyric acidA receptors in humans. Anesthesia and Analgesia. 99: 1420-1426. PMID 15502041 DOI: 10.1213/01.ANE.0000135409.81842.31  0.389
2004 Sinkkonen ST, Vekovischeva OY, Möykkynen T, Ogris W, Sieghart W, Wisden W, Korpi ER. Behavioural correlates of an altered balance between synaptic and extrasynaptic GABAAergic inhibition in a mouse model. The European Journal of Neuroscience. 20: 2168-78. PMID 15450096 DOI: 10.1111/J.1460-9568.2004.03684.X  0.833
2004 Sinkkonen ST, Lüscher B, Lüddens H, Korpi ER. Autoradiographic imaging of altered synaptic alphabetagamma2 and extrasynaptic alphabeta GABAA receptors in a genetic mouse model of anxiety. Neurochemistry International. 44: 539-47. PMID 15209422 DOI: 10.1016/J.Neuint.2003.08.008  0.762
2004 Sinkkonen ST, Lindén AM, Korpi ER, Wong G. Selective reduction of gamma-aminobutyric acid type A receptor delta subunit mRNA levels by MK-801 in rat dentate gyrus. Neuroscience Letters. 364: 106-9. PMID 15196688 DOI: 10.1016/j.neulet.2004.04.022  0.726
2004 Ingman K, Sallinen J, Honkanen A, Korpi ER. Comparison of deramciclane to benzodiazepine agonists in behavioural activity of mice and in alcohol drinking of alcohol-preferring rats. Pharmacology, Biochemistry, and Behavior. 77: 847-54. PMID 15099931 DOI: 10.1016/j.pbb.2004.02.015  0.343
2004 Uusi-Oukari M, Kosonen P, Homanics GE, Korpi ER. Brain regional heterogeneity of pH effects on GABA(A) receptor-associated [35s]TBPS binding. Neurochemical Research. 29: 771-80. PMID 15098940 DOI: 10.1023/B:Nere.0000018849.54169.C4  0.789
2004 Martikainen IK, Lauk K, Möykkynen T, Holopainen IE, Korpi ER, Uusi-Oukari M. Kainate down-regulates a subset of GABAA receptor subunits expressed in cultured mouse cerebellar granule cells. Cerebellum (London, England). 3: 27-38. PMID 15072265 DOI: 10.1080/14734220310020876  0.81
2003 Korpi ER, Lindsberg PJ. [New challenges of brain research]. Duodecim; Laaketieteellinen Aikakauskirja. 119: 1461-3. PMID 14502824  0.243
2003 Laurén HB, Pitkänen A, Nissinen J, Soini SL, Korpi ER, Holopainen IE. Selective changes in gamma-aminobutyric acid type A receptor subunits in the hippocampus in spontaneously seizing rats with chronic temporal lobe epilepsy. Neuroscience Letters. 349: 58-62. PMID 12946586 DOI: 10.1016/s0304-3940(03)00735-3  0.406
2003 Sinkkonen ST, Mansikkamäki S, Möykkynen T, Lüddens H, Uusi-Oukari M, Korpi ER. Receptor subtype-dependent positive and negative modulation of GABA(A) receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug. Molecular Pharmacology. 64: 753-63. PMID 12920213 DOI: 10.1124/mol.64.3.753  0.833
2003 Ingman K, Salvadori S, Lazarus L, Korpi ER, Honkanen A. Selective δ-opioid receptor antagonist N,N(CH3)2-Dmt-Tic-OH does not reduce ethanol intake in alcohol-preferring AA rats Addiction Biology. 8: 173-179. PMID 12850776 DOI: 10.1080/1355621031000117400  0.375
2003 Möykkynen T, Korpi ER, Lovinger DM. Ethanol inhibits alpha-amino-3-hydyroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor function in central nervous system neurons by stabilizing desensitization. The Journal of Pharmacology and Experimental Therapeutics. 306: 546-55. PMID 12734392 DOI: 10.1124/jpet.103.050666  0.806
2003 Vekovischeva O, Uusi-Oukari M, Korpi ER. Tolerance to diazepam-induced motor impairment: a study with GABAA receptor alpha6 subunit knockout mice. Neurochemical Research. 28: 757-64. PMID 12716027 DOI: 10.1023/a:1022870002722  0.827
2003 Juhila J, Haapalinna A, Sirviö J, Sallinen J, Honkanen A, Korpi ER, Scheinin M. The alpha2-adrenoceptor antagonist atipamezole reduces the development and expression of d-amphetamine-induced behavioural sensitization. Naunyn-Schmiedeberg's Archives of Pharmacology. 367: 274-80. PMID 12644900 DOI: 10.1007/s00210-003-0695-6  0.38
2003 Raatesalmi K, Virtanen A, Sarviharju M, Pelto-Huikko And M, Korpi ER. Reduced adrenal activation in a rat line selected for high alcohol sensitivity. Alcoholism, Clinical and Experimental Research. 26: 1344-9. PMID 12351928 DOI: 10.1097/01.ALC.0000030560.28034.5D  0.223
2003 Soini SL, Hyytiä P, Korpi ER. Brain regional mu-opioid receptor function in rat lines selected for differences in alcohol preference. European Journal of Pharmacology. 448: 157-63. PMID 12144936 DOI: 10.1016/s0014-2999(02)01948-9  0.335
2002 Korpi ER, Gründer G, Lüddens H. Drug interactions at GABA(A) receptors. Progress in Neurobiology. 67: 113-59. PMID 12126658 DOI: 10.1016/s0301-0082(02)00013-8  0.492
2002 Lintunen M, Raatesalmi K, Sallmen T, Anichtchik O, Karlstedt K, Kaslin J, Kiianmaa K, Korpi ER, Panula P. Low brain histamine content affects ethanol-induced motor impairment. Neurobiology of Disease. 9: 94-105. PMID 11848689 DOI: 10.1006/nbdi.2001.0453  0.346
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