Robert D. Pinnock - Publications


81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2003 Maneuf YP, Gonzalez MI, Sutton KS, Chung FZ, Pinnock RD, Lee K. Cellular and molecular action of the putative GABA-mimetic, gabapentin. Cellular and Molecular Life Sciences : Cmls. 60: 742-50. PMID 12785720 DOI: 10.1007/s00018-003-2108-x  0.64
2003 Ciruela A, Dixon AK, Bramwell S, Gonzalez MI, Pinnock RD, Lee K. Identification of MEK1 as a novel target for the treatment of neuropathic pain. British Journal of Pharmacology. 138: 751-6. PMID 12642375 DOI: 10.1038/sj.bjp.0705103  0.64
2003 Smith MA, Herson PS, Lee K, Pinnock RD, Ashford ML. Hydrogen-peroxide-induced toxicity of rat striatal neurones involves activation of a non-selective cation channel. The Journal of Physiology. 547: 417-25. PMID 12562896 DOI: 10.1113/jphysiol.2002.034561  0.64
2002 Martin DJ, McClelland D, Herd MB, Sutton KG, Hall MD, Lee K, Pinnock RD, Scott RH. Gabapentin-mediated inhibition of voltage-activated Ca2+ channel currents in cultured sensory neurones is dependent on culture conditions and channel subunit expression. Neuropharmacology. 42: 353-66. PMID 11897114 DOI: 10.1016/S0028-3908(01)00181-2  0.64
2002 Sutton KG, Martin DJ, Pinnock RD, Lee K, Scott RH. Gabapentin inhibits high-threshold calcium channel currents in cultured rat dorsal root ganglion neurones. British Journal of Pharmacology. 135: 257-65. PMID 11786502 DOI: 10.1038/sj.bjp.0704439  0.64
2001 Fahmi AI, Patel M, Stevens EB, Fowden AL, John JE, Lee K, Pinnock R, Morgan K, Jackson AP, Vandenberg JI. The sodium channel β-subunits SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart Journal of Physiology. 537: 693-700. PMID 11744748 DOI: 10.1113/jphysiol.2001.012691  0.64
2001 Patel MK, Pinnock RD, Lee K. Adenosine exerts multiple effects in dorsal horn neurones of the adult rat spinal cord. Brain Research. 920: 19-26. PMID 11716807 DOI: 10.1016/S0006-8993(01)02844-X  0.64
2001 Yusaf SP, Goodman J, Gonzalez IM, Bramwell S, Pinnock RD, Dixon AK, Lee K. Streptozocin-induced neuropathy is associated with altered expression of voltage-gated calcium channel subunit mRNAs in rat dorsal root ganglion neurones. Biochemical and Biophysical Research Communications. 289: 402-6. PMID 11716487 DOI: 10.1006/bbrc.2001.5943  0.64
2001 Yusaf SP, Goodman J, Pinnock RD, Dixon AK, Lee K. Expression of voltage-gated calcium channel subunits in rat dorsal root ganglion neurons. Neuroscience Letters. 311: 137-41. PMID 11567797 DOI: 10.1016/S0304-3940(01)02038-9  0.64
2001 Shah BS, Gonzalez MI, Bramwell S, Pinnock RD, Lee K, Dixon AK. Beta3, a novel auxiliary subunit for the voltage gated sodium channel is upregulated in sensory neurones following streptozocin induced diabetic neuropathy in rat. Neuroscience Letters. 309: 1-4. PMID 11489532 DOI: 10.1016/S0304-3940(01)01976-0  0.64
2001 Shah BS, Stevens EB, Pinnock RD, Dixon AK, Lee K. Developmental expression of the novel voltage-gated sodium channel auxiliary subunit beta3, in rat CNS. The Journal of Physiology. 534: 763-76. PMID 11483707 DOI: 10.1111/j.1469-7793.2001.t01-1-00763.x  0.64
2001 Stevens EB, Cox PJ, Shah BS, Dixon AK, Richardson PJ, Pinnock RD, Lee K. Tissue distribution and functional expression of the human voltage-gated sodium channel beta3 subunit. PflüGers Archiv : European Journal of Physiology. 441: 481-8. PMID 11212211 DOI: 10.1007/s004240000449  0.64
2000 Shah BS, Stevens EB, Gonzalez MI, Bramwell S, Pinnock RD, Lee K, Dixon AK. beta3, a novel auxiliary subunit for the voltage-gated sodium channel, is expressed preferentially in sensory neurons and is upregulated in the chronic constriction injury model of neuropathic pain. The European Journal of Neuroscience. 12: 3985-90. PMID 11069594 DOI: 10.1046/j.1460-9568.2000.00294.x  0.64
2000 Patel MK, Gonzalez MI, Bramwell S, Pinnock RD, Lee K. Gabapentin inhibits excitatory synaptic transmission in the hyperalgesic spinal cord. British Journal of Pharmacology. 130: 1731-4. PMID 10952660 DOI: 10.1038/sj.bjp.0703530  0.64
2000 Preston Z, Richardson PJ, Pinnock RD, Lee K. NK-3 receptors are expressed on mouse striatal gamma-aminobutyric acid-ergic interneurones and evoke [(3)H] gamma-aminobutyric acid release. Neuroscience Letters. 284: 89-92. PMID 10771169 DOI: 10.1016/S0304-3940(00)00968-X  0.64
2000 Morgan K, Stevens EB, Shah B, Cox PJ, Dixon AK, Lee K, Pinnock RD, Hughes J, Richardson PJ, Mizuguchi K, Jackson AP. beta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics. Proceedings of the National Academy of Sciences of the United States of America. 97: 2308-13. PMID 10688874 DOI: 10.1073/pnas.030362197  0.64
2000 Dixon AK, Richardson PJ, Pinnock RD, Lee K. Gene-expression analysis at the single-cell level. Trends in Pharmacological Sciences. 21: 65-70. PMID 10664611 DOI: 10.1016/S0165-6147(99)01433-9  0.64
2000 Preston Z, Lee K, Widdowson L, Richardson PJ, Pinnock RD. Tachykinins increase [3H]acetylcholine release in mouse striatum through multiple receptor subtypes. Neuroscience. 95: 367-76. PMID 10658616 DOI: 10.1016/S0306-4522(99)00440-6  0.64
2000 Richardson PJ, Dixon AK, Lee K, Bell MI, Cox PJ, Williams R, Pinnock RD, Freeman TC. Correlating physiology with gene expression in striatal cholinergic neurones. Journal of Neurochemistry. 74: 839-46. PMID 10646537 DOI: 10.1046/j.1471-4159.2000.740839.x  0.64
1999 Lee K, Dixon AK, Pinnock RD. Serotonin depolarizes hippocampal interneurones in the rat stratum oriens by interaction with 5HT2 receptors. Neuroscience Letters. 270: 56-8. PMID 10454145 DOI: 10.1016/S0304-3940(99)00449-8  0.64
1999 Lee K, Dixon AK, Gonzalez I, Stevens EB, McNulty S, Oles R, Richardson PJ, Pinnock RD, Singh L. Bombesin-like peptides depolarize rat hippocampal interneurones through interaction with subtype 2 bombesin receptors. The Journal of Physiology. 518: 791-802. PMID 10420015 DOI: 10.1111/j.1469-7793.1999.0791p.x  0.64
1999 Stevens EB, Shah BS, Pinnock RD, Lee K. Bombesin receptors inhibit G protein-coupled inwardly rectifying K+ channels expressed in Xenopus oocytes through a protein kinase C-dependent pathway. Molecular Pharmacology. 55: 1020-7. PMID 10347243  0.64
1999 Rossant CJ, Pinnock RD, Hughes J, Hall MD, McNulty S. Corticotropin-releasing factor type 1 and type 2alpha receptors regulate phosphorylation of calcium/cyclic adenosine 3',5'-monophosphate response element-binding protein and activation of p42/p44 mitogen-activated protein kinase. Endocrinology. 140: 1525-36. PMID 10098484 DOI: 10.1210/endo.140.4.6656  0.64
1999 Lee K, Dixon AK, Richardson PJ, Pinnock RD. Glucose-receptive neurones in the rat ventromedial hypothalamus express KATP channels composed of Kir6.1 and SUR1 subunits. The Journal of Physiology. 515: 439-52. PMID 10050011  0.64
1999 Herson PS, Lee K, Pinnock RD, Hughes J, Ashford ML. Hydrogen peroxide induces intracellular calcium overload by activation of a non-selective cation channel in an insulin-secreting cell line. The Journal of Biological Chemistry. 274: 833-41. PMID 9873022 DOI: 10.1074/jbc.274.2.833  0.64
1998 Ashwood V, Brownhill V, Higginbottom M, Horwell DC, Hughes J, Lewthwaite RA, McKnight AT, Pinnock RD, Pritchard MC, Suman-Chauhan N, Webb C, Williams SC. PD 176252--the first high affinity non-peptide gastrin-releasing peptide (BB2) receptor antagonist. Bioorganic & Medicinal Chemistry Letters. 8: 2589-94. PMID 9873586 DOI: 10.1016/S0960-894X(98)00462-4  0.64
1998 Young KW, Pinnock RD, Nahorski SR. Determination of the inositol (1,4,5) trisphosphate requirement for histamine- and substance P-induced Ca2+ mobilisation in human U373 MG astrocytoma cells. Cell Calcium. 24: 59-70. PMID 9793689 DOI: 10.1016/S0143-4160(98)90089-6  0.64
1998 Padia JK, Field M, Hinton J, Meecham K, Pablo J, Pinnock R, Roth BD, Singh L, Suman-Chauhan N, Trivedi BK, Webdale L. Novel nonpeptide CCK-B antagonists: design and development of quinazolinone derivatives as potent, selective, and orally active CCK-B antagonists. Journal of Medicinal Chemistry. 41: 1042-9. PMID 9544204 DOI: 10.1021/jm970373j  0.64
1998 Young KW, Pinnock RD, Gibson WJ, Young JM. Dual effects of histamine and substance P on intracellular calcium levels in human U373 MG astrocytoma cells: role of protein kinase C. British Journal of Pharmacology. 123: 545-57. PMID 9504396 DOI: 10.1038/sj.bjp.0701620  0.64
1997 Reynolds T, Pinnock RD. Neuromedin C decreases potassium conductance and increases a non-specific conductance in rat suprachiasmatic neurones in brain slices in vitro. Brain Research. 750: 67-80. PMID 9098531 DOI: 10.1016/S0006-8993(96)01332-7  0.64
1997 Padia JK, Chilvers H, Daum P, Pinnock R, Suman-Chauhan N, Webdale L, Trivedi BK. Design and synthesis of novel nonpeptide CCK-B receptor antagonists Bioorganic and Medicinal Chemistry Letters. 7: 805-810. DOI: 10.1016/S0960-894X(97)00108-X  0.64
1996 Horwell DC, Howson W, Naylor D, Osborne S, Pinnock RD, Ratcliffe GS, Suman-Chauhan N. Alanine scan and N-methyl amide derivatives of Ac-bombesin[7-14]. Development of a proposed binding conformation at the neuromedin B (NMB) and gastrin releasing peptide (GRP) receptors. International Journal of Peptide and Protein Research. 48: 522-31. PMID 8985785  0.64
1996 Woodruff GN, Hall MD, Reynolds T, Pinnock RD. Bombesin receptors in the brain. Annals of the New York Academy of Sciences. 780: 223-43. PMID 8602736 DOI: 10.1111/j.1749-6632.1996.tb15126.x  0.64
1996 Eden JM, Hall MD, Higginbottom M, Horwell DC, Howson W, Hughes J, Jordan RE, Lewthwaite RA, Martin K, McKnight AT, O'Toole JC, Pinnock RD, Pritchard MC, Suman-Chauhan N, Williams SC. PD 165929 - The first high affinity non-peptide neuromedin-B (NMB) receptor selective antagonist Bioorganic and Medicinal Chemistry Letters. 6: 2617-2622. DOI: 10.1016/0960-894X(96)00481-7  0.64
1995 De Felipe C, Pinnock RD, Hunt SP. Modulation of chemotropism in the developing spinal cord by substance P. Science (New York, N.Y.). 267: 899-902. PMID 7531367  0.64
1994 Pinnock RD, Woodruff GN. The non-peptide neurotensin receptor antagonist SR48692 is not a potent antagonist of neurotensin(8-13) responses of rat substantia nigra neurones in vitro. Neuroscience Letters. 172: 175-8. PMID 8084529 DOI: 10.1016/0304-3940(94)90690-4  0.64
1994 Boden PR, Pinnock RD, Pritchard MC, Woodruff GN. Evaluation of a series of novel CCKB antagonists using a functional assay in the rat central nervous system. British Journal of Pharmacology. 112: 666-70. PMID 8075886  0.64
1994 Keegan KD, Woodruff GN, Pinnock RD. The pharmacology of neurotensin analogues on neurones in the rat substantia nigra, pars compacta in vitro. European Journal of Pharmacology. 253: 131-7. PMID 8013539 DOI: 10.1016/0014-2999(94)90767-6  0.64
1994 Pinnock RD, Reynolds T, Woodruff GN. Different types of bombesin receptors on neurons in the dorsal raphe nucleus and the rostral hypothalamus in rat brain slices in vitro. Brain Research. 653: 119-24. PMID 7982044 DOI: 10.1016/0006-8993(94)90379-4  0.64
1994 Pinnock RD, Suman-Chauhan N, Daum P, Hill DR, Woodruff GN. The cholecystokinin-induced increase in intracellular calcium in AR42J cells is mediated by CCKB receptors linked to internal calcium stores. Neuropeptides. 27: 175-83. PMID 7816188 DOI: 10.1016/0143-4179(94)90068-X  0.64
1994 Pinnock RD, Suman-Chauhan N, Chung FZ, Webdale L, Madden Z, Hill DR, Woodruff GN. Characterization of tachykinin mediated increases in [Ca2+]i in Chinese hamster ovary cells expressing human tachykinin NK3 receptors. European Journal of Pharmacology. 269: 73-8. PMID 7530208  0.64
1994 Suman-Chauhan N, Grimson P, Guard S, Madden Z, Fu-Zon C, Watling K, Pinnock R, Woodruff G. Characterisation of [125I][MePhe7]neurokinin B binding to tachykinin NK3 receptors: evidence for interspecies variance European Journal of Pharmacology. 269: 65-72. PMID 7530207  0.64
1994 Puttick RM, Pinnock RD, Woodruff GN. Galanin-induced membrane depolarization of neonatal rat cultured dorsal root ganglion cells. European Journal of Pharmacology. 254: 303-6. PMID 7516886 DOI: 10.1016/0014-2999(94)90471-5  0.64
1992 Keegan KD, Woodruff GN, Pinnock RD. The selective NK3 receptor agonist senktide excites a subpopulation of dopamine-sensitive neurones in the rat substantia nigra pars compacta in vitro. British Journal of Pharmacology. 105: 3-5. PMID 1375857  0.64
1992 Pinnock RD. Activation of kappa-opioid receptors depresses electrically evoked excitatory postsynaptic potentials on 5-HT-sensitive neurones in the rat dorsal raphé nucleus in vitro. Brain Research. 583: 237-46. PMID 1354563  0.64
1992 Pinnock RD, Richardson RS, Boden PR, Woodruff GN. Cholecystokinin receptors in the rat brain in vitro: Sensitivity to CCK(A) and CCK(B) receptor agonists and antagonists Molecular Neuropharmacology. 1: 211-218.  0.64
1991 Woodruff GN, Hill DR, Boden P, Pinnock R, Singh L, Hughes J. Functional role of brain CCK receptors Neuropeptides. 19: 45-56. PMID 1881532 DOI: 10.1016/0143-4179(91)90082-T  0.64
1991 Pinnock RD, Woodruff GN. Bombesin excites a subpopulation of 5-hydroxytryptamine-sensitive neurones in the rat dorsal raphe nucleus in vitro. The Journal of Physiology. 440: 55-65. PMID 1804977  0.64
1991 Boden PR, Woodruff GN, Pinnock RD. Pharmacology of a cholecystokinin receptor on 5-hydroxytryptamine neurones in the dorsal raphe of the rat brain. British Journal of Pharmacology. 102: 635-8. PMID 1364831  0.64
1991 Pinnock RD, Woodruff GN. Bombesin, neuromedin B and gastrin-releasing peptide excite a subpopulation of 5-hydroxytryptamine neurones in the rat dorsal raphe nucleus in vitro Journal of Physiology. 435: 46P.  0.64
1990 Marshall FH, Barnes S, Pinnock RD, Hughes J. Characterization of cholecystokinin octapeptide-stimulated endogenous dopamine release from rat nucleus accumbens in vitro. British Journal of Pharmacology. 99: 845-8. PMID 2361176  0.64
1990 Hughes J, Boden P, Costall B, Domeney A, Kelly E, Horwell DC, Hunter JC, Pinnock RD, Woodruff GN. Development of a class of selective cholecystokinin type B receptor antagonists having potent anxiolytic activity. Proceedings of the National Academy of Sciences of the United States of America. 87: 6728-32. PMID 1975695  0.64
1989 Yamamoto D, Pinnock RD, Sattelle DB. Switching between two types of bursting activity of single ca-activated k channels in dissociated neurons. Journal of Neuroendocrinology. 1: 89-94. PMID 19210464 DOI: 10.1111/j.1365-2826.1989.tb00085.x  0.64
1989 Sattelle DB, Pinnock RD, Lummis SCR. Voltage-independent block of a neuronal nicotinic aetylcholine receptor by N-methyl lycaconitine Journal of Experimental Biology. 142: 215-224.  0.64
1989 Yamamoto D, Pinnock RD, Sattelle DB. Switching between two types of bursting activity of single Ca2+-activated K+ channels in dissociated neurons Journal of Neuroendocrinology. 1: 89-94.  0.64
1988 Pinnock RD, Sattelle DB, Gration KA, Harrow ID. Actions of potent cholinergic anthelmintics (morantel, pyrantel and levamisole) on an identified insect neurone reveal pharmacological differences between nematode and insect acetylcholine receptors. Neuropharmacology. 27: 843-8. PMID 3216964 DOI: 10.1016/0028-3908(88)90101-3  0.64
1988 Pinnock RD, Lummis SC, Chiappinelli VA, Sattelle DB. Kappa-bungarotoxin blocks an alpha-bungarotoxin-sensitive nicotinic receptor in the insect central nervous system. Brain Research. 458: 45-52. PMID 3208100 DOI: 10.1016/0006-8993(88)90494-5  0.64
1988 Pinnock RD, David JA, Sattelle DB. Ionic events following GABA receptor activation in an identified insect motor neuron. Proceedings of the Royal Society of London. Series B, Biological Sciences. 232: 457-70. PMID 2451253  0.64
1988 Sattelle DB, Pinnock RD, Wafford KA, David JA. GABA receptors on the cell-body membrane of an identified insect motor neuron. Proceedings of the Royal Society of London. Series B, Biological Sciences. 232: 443-56. PMID 2451252  0.64
1987 Pinnock RD, Sattelle DB. Dissociation and maintenance in vitro of neurones from adult cockroach (Periplaneta americana) and housefly (Musca domestica). Journal of Neuroscience Methods. 20: 195-202. PMID 3626615 DOI: 10.1016/0165-0270(87)90051-3  0.64
1987 Suppes T, Pinnock RD. Sensitivity of neuronal dopamine response in the substantia nigra and ventral tegmentum to clozapine, metoclopramide and SCH 23390. Neuropharmacology. 26: 331-7. PMID 3295579 DOI: 10.1016/0028-3908(87)90185-7  0.64
1985 Pinnock RD. Neurotensin depolarizes substantia nigra dopamine neurones. Brain Research. 338: 151-4. PMID 4027584 DOI: 10.1016/0006-8993(85)90258-6  0.64
1985 Harris NC, Pinnock RD, Woodruff GN. Zetidoline blocks dopamine autoreceptors in the rat substantia nigra. Neuropharmacology. 24: 33-6. PMID 2858831 DOI: 10.1016/0028-3908(85)90092-9  0.64
1985 Hunter JC, Goedert M, Pinnock RD. Mammalian tachykinin-induced hydrolysis of inositol phospholipids in rat brain slices. Biochemical and Biophysical Research Communications. 127: 616-22. PMID 2579657 DOI: 10.1016/S0006-291X(85)80205-9  0.64
1984 Pinnock RD. Action of putative dopamine receptor agonists, TL-99, 3-PPP and RDS-127 on substantia nigra neurons. Brain Research. 292: 190-3. PMID 6697209 DOI: 10.1016/0006-8993(84)90907-7  0.64
1984 Pinnock RD. Hyperpolarizing action of baclofen on neurons in the rat substantia nigra slice. Brain Research. 322: 337-40. PMID 6509322 DOI: 10.1016/0006-8993(84)90129-X  0.64
1984 Mantyh PW, Pinnock RD, Downes CP, Goedert M, Hunt SP. Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS. Nature. 309: 795-7. PMID 6204206 DOI: 10.1038/309795a0  0.64
1984 Pinnock RD. The actions of antipsychotic drugs on dopamine receptors in the rat substantia nigra. British Journal of Pharmacology. 81: 631-5. PMID 6144343  0.64
1984 Goedert M, Pinnock RD, Downes CP, Mantyh PW, Emson PC. Neurotensin stimulates inositol phospholipid hydrolysis in rat brain slices. Brain Research. 323: 193-7. PMID 6098333 DOI: 10.1016/0006-8993(84)90288-9  0.64
1983 Pinnock RD. Sensitivity of compacta neurones in the rat substantia nigra slice to dopamine agonists. European Journal of Pharmacology. 96: 269-76. PMID 6676108 DOI: 10.1016/0014-2999(83)90316-3  0.64
1983 Cheeseman HJ, Pinnock RD, Henderson G. Substance P excitation of rat locus coeruleus neurones. European Journal of Pharmacology. 94: 93-9. PMID 6197310 DOI: 10.1016/0014-2999(83)90445-4  0.64
1983 Dray A, Hanley MR, Pinnock RD, Sandberg BE. A comparison of the release of substance P and some synthetic analogues from micropipettes by microiontophoresis or pressure. Neuropharmacology. 22: 859-63. PMID 6194470 DOI: 10.1016/0028-3908(83)90132-6  0.64
1983 Pinnock RD, Woodruff GN, Turnbull MJ. Actions of substance P, MIF, TRH and related peptides in the substantia nigra, caudate nucleus and nucleus accumbens. Neuropharmacology. 22: 687-96. PMID 6193454 DOI: 10.1016/0028-3908(83)90091-6  0.64
1983 Pinnock RD. Inhibition of pars compacta neurones by dopamine in slices of rat substantia nigra maintained in vitro Journal of Physiology. 88P-89P.  0.64
1982 Iversen LL, Hanley MR, Sandberg BE, Lee CM, Pinnock RD, Watson SP. Substance P receptors in the nervous system and possible receptor subtypes. Ciba Foundation Symposium. 186-205. PMID 6183070  0.64
1982 Pinnock RD, Dray A. Differential sensitivity of presumed dopaminergic and non-dopaminergic neurones in rat substantia nigra to electrophoretically applied substance P. Neuroscience Letters. 29: 153-8. PMID 6178059 DOI: 10.1016/0304-3940(82)90345-7  0.64
1982 Dray A, Marshall G, Pinnock RD. A simple method for the construction of coaxial multibarrelled micropipettes with exchangeable components. Journal of Neuroscience Methods. 5: 121-5. PMID 6120263 DOI: 10.1016/0165-0270(82)90058-9  0.64
1982 Cheeseman HJ, Pinnock RD, Henderson G. Characterization of substance P-mediated excitation in the rat locus coeruleus Regulatory Peptides. 4: 359.  0.64
1982 Dray A, Pinnock RD. Substance P depolarizes a population of rat dorsal root ganglion (DRG) neurones Federation Proceedings. 41: No. 4734.  0.64
1979 Pinnock RD, Turnbull MJ, Woodruff GN. Effects of peptides on neurones in the substantia nigra and nucleus accumbens [proceedings]. British Journal of Pharmacology. 67: 429P-430P. PMID 497554  0.64
1979 Pinnock RD, Woodruff GN, Turnbull MJ. Sulpiride blocks the action of dopamine in the rat substantia nigra. European Journal of Pharmacology. 56: 413-4. PMID 477736 DOI: 10.1016/0014-2999(79)90275-9  0.64
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