| Year |
Citation |
Score |
| 2023 |
Sharma V, Oliveira MM, Sood R, Khlaifia A, Lou D, Hooshmandi M, Hung TY, Mahmood N, Reeves M, Ho-Tieng D, Cohen N, Cheng PC, Rahim MMA, Prager-Khoutorsky M, Kaufman RJ, ... ... Khoutorsky A, et al. mRNA translation in astrocytes controls hippocampal long-term synaptic plasticity and memory. Proceedings of the National Academy of Sciences of the United States of America. 120: e2308671120. PMID 38015848 DOI: 10.1073/pnas.2308671120 |
0.471 |
|
| 2023 |
Wong C, Tavares-Ferreira D, Thörn Perez C, Sharif B, Uttam S, Amiri M, Lister KC, Hooshmandi M, Nguyen V, Séguéla P, Sonenberg N, Price TJ, Gkogkas CG, Khoutorsky A. 4E-BP1-dependent translation in nociceptors controls mechanical hypersensitivity via TRIM32/type I interferon signaling. Science Advances. 9: eadh9603. PMID 37922363 DOI: 10.1126/sciadv.adh9603 |
0.732 |
|
| 2023 |
Hooshmandi M, Sharma V, Thörn Perez C, Sood R, Krimbacher K, Wong C, Lister KC, Ureña Guzmán A, Bartley TD, Rocha C, Maussion G, Nadler E, Roque PM, Gantois I, Popic J, ... ... Khoutorsky A, et al. Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome. Neuron. PMID 37473758 DOI: 10.1016/j.neuron.2023.06.017 |
0.723 |
|
| 2023 |
Chalkiadaki K, Statoulla E, Zafeiri M, Haji N, Lacaille JC, Powell CM, Jafarnejad SM, Khoutorsky A, Gkogkas CG. Reversal of memory and autism-related phenotypes in mice via inhibition of . Frontiers in Cell and Developmental Biology. 11: 1205112. PMID 37293130 DOI: 10.3389/fcell.2023.1205112 |
0.707 |
|
| 2022 |
Roque PS, Thörn Perez C, Hooshmandi M, Wong C, Eslamizade MJ, Heshmati S, Brown N, Sharma V, Lister KC, Goyon VM, Neagu-Lund LE, Shen C, Daccache N, Sato H, Sato T, ... ... Khoutorsky A, et al. Parvalbumin interneuron loss mediates repeated anesthesia-induced memory deficits in mice. The Journal of Clinical Investigation. PMID 36394958 DOI: 10.1172/JCI159344 |
0.675 |
|
| 2022 |
Chalkiadaki K, Hooshmandi M, Lach G, Statoulla E, Simbriger K, Amorim IS, Kouloulia S, Zafeiri M, Pothos P, Bonneil É, Gantois I, Popic J, Kim SH, Wong C, Cao R, ... ... Khoutorsky A, et al. Mnk1/2 kinases regulate memory and autism-related behaviours via Syngap1. Brain : a Journal of Neurology. PMID 36315645 DOI: 10.1093/brain/awac398 |
0.744 |
|
| 2022 |
Toboz P, Amiri M, Tabatabaei N, Dufour CR, Kim SH, Fillebeen C, Ayemoba CE, Khoutorsky A, Nairz M, Shao L, Pajcini KV, Kim KW, Giguère V, Oliveira RL, Constante M, et al. The amino acid sensor GCN2 controls red blood cell clearance and iron metabolism through regulation of liver macrophages. Proceedings of the National Academy of Sciences of the United States of America. 119: e2121251119. PMID 35994670 DOI: 10.1073/pnas.2121251119 |
0.401 |
|
| 2022 |
Farooq Z, Kusuma F, Burke P, Dufour CR, Lee D, Tabatabaei N, Toboz P, Radovani E, Greenblatt J, Rehman J, Class J, Khoutorsky A, Fonseca BD, Richner JM, Mercier E, et al. The amino acid sensor GCN2 suppresses Terminal Oligopyrimidine (TOP) mRNA translation via La-related Protein 1 (LARP1). The Journal of Biological Chemistry. 102277. PMID 35863436 DOI: 10.1016/j.jbc.2022.102277 |
0.315 |
|
| 2022 |
Tansley S, Gu N, Guzmán AU, Cai W, Wong C, Lister K, Muñoz-Pino E, Yousefpour N, Roome RB, Heal J, Wu N, Castonguay A, Lean G, Muir EM, Kania A, ... ... Khoutorsky A, et al. Microglia-mediated degradation of perineuronal nets promotes pain. Science (New York, N.Y.). eabl6773. PMID 35617374 DOI: 10.1126/science.abl6773 |
0.623 |
|
| 2021 |
Roque PS, Hooshmandi M, Neagu-Lund L, Yin S, Yousefpour N, Sato H, Sato T, Nakadate Y, Kawakami A, Tahmasebi S, Ribeiro-da-Silva A, Gkogkas CG, Prager-Khoutorsky M, Schricker T, Wykes L, ... Khoutorsky A, et al. Intranasal insulin rescues repeated anesthesia-induced deficits in synaptic plasticity and memory and prevents apoptosis in neonatal mice via mTORC1. Scientific Reports. 11: 15490. PMID 34326413 DOI: 10.1038/s41598-021-94849-3 |
0.666 |
|
| 2021 |
Hooshmandi M, Truong VT, Fields E, Thomas RE, Wong C, Sharma V, Gantois I, Soriano Roque P, Chalkiadaki K, Wu N, Chakraborty A, Tahmasebi S, Prager-Khoutorsky M, Sonenberg N, Suvrathan A, ... ... Khoutorsky A, et al. 4E-BP2-dependent translation in cerebellar Purkinje cells controls spatial memory but not autism-like behaviors. Cell Reports. 35: 109036. PMID 33910008 DOI: 10.1016/j.celrep.2021.109036 |
0.73 |
|
| 2021 |
Sharma V, Sood R, Lou D, Hung TY, Lévesque M, Han Y, Levett JY, Wang P, Murthy S, Tansley S, Wang S, Siddiqui N, Tahmasebi S, Rosenblum K, Avoli M, ... ... Khoutorsky A, et al. 4E-BP2-dependent translation in parvalbumin neurons controls epileptic seizure threshold. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33876772 DOI: 10.1073/pnas.2025522118 |
0.496 |
|
| 2020 |
Sharma V, Sood R, Khlaifia A, Eslamizade MJ, Hung TY, Lou D, Asgarihafshejani A, Lalzar M, Kiniry SJ, Stokes MP, Cohen N, Nelson AJ, Abell K, Possemato AP, Gal-Ben-Ari S, ... ... Khoutorsky A, et al. eIF2α controls memory consolidation via excitatory and somatostatin neurons. Nature. PMID 33029011 DOI: 10.1038/s41586-020-2805-8 |
0.495 |
|
| 2020 |
Simbriger K, Amorim IS, Lach G, Chalkiadaki K, Kouloulia S, Jafarnejad SM, Khoutorsky A, Gkogkas CG. Uncovering memory-related gene expression in contextual fear conditioning using ribosome profiling. Progress in Neurobiology. 101903. PMID 32860876 DOI: 10.1016/J.Pneurobio.2020.101903 |
0.64 |
|
| 2019 |
Kouloulia S, Hallin EI, Simbriger K, Amorim IS, Lach G, Amvrosiadis T, Chalkiadaki K, Kampaite A, Truong VT, Hooshmandi M, Jafarnejad SM, Skehel P, Kursula P, Khoutorsky A, Gkogkas CG. Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity. Cell Reports. 29: 3620-3635.e7. PMID 31825840 DOI: 10.1016/J.Celrep.2019.11.023 |
0.683 |
|
| 2019 |
Simbriger K, Amorim IS, Chalkiadaki K, Lach G, Jafarnejad SM, Khoutorsky A, Gkogkas CG. Monitoring translation in synaptic fractions using a ribosome profiling strategy. Journal of Neuroscience Methods. 108456. PMID 31610213 DOI: 10.1016/J.Jneumeth.2019.108456 |
0.667 |
|
| 2019 |
Wiebe S, Nagpal A, Truong VT, Park J, Skalecka A, He AJ, Gamache K, Khoutorsky A, Gantois I, Sonenberg N. Inhibitory interneurons mediate autism-associated behaviors via 4E-BP2. Proceedings of the National Academy of Sciences of the United States of America. PMID 31427534 DOI: 10.1073/Pnas.1908126116 |
0.693 |
|
| 2018 |
Uttam S, Wong C, Amorim IS, Jafarnejad SM, Tansley SN, Yang J, Prager-Khoutorsky M, Mogil JS, Gkogkas CG, Khoutorsky A. Translational profiling of dorsal root ganglia and spinal cord in a mouse model of neuropathic pain. Neurobiology of Pain (Elsevier, Inc.). 4: 35-44. PMID 30906902 DOI: 10.1016/J.Ynpai.2018.04.001 |
0.658 |
|
| 2018 |
Uttam S, Wong C, Price TJ, Khoutorsky A. eIF4E-Dependent Translational Control: A Central Mechanism for Regulation of Pain Plasticity. Frontiers in Genetics. 9: 470. PMID 30459806 DOI: 10.3389/fgene.2018.00470 |
0.366 |
|
| 2018 |
Megat S, Ray PR, Moy JK, Lou TF, Barragan-Iglesias P, Li Y, Pradhan G, Wanghzou A, Ahmad A, Burton MD, North RY, Dougherty PM, Khoutorsky A, Sonenberg N, Webster KR, et al. Nociceptor translational profiling reveals the Ragulator-Rag GTPase complex as a critical generator of neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30459229 DOI: 10.1523/Jneurosci.2661-18.2018 |
0.508 |
|
| 2018 |
Gantois I, Popic J, Khoutorsky A, Sonenberg N. Metformin for Treatment of Fragile X Syndrome and Other Neurological Disorders. Annual Review of Medicine. PMID 30365357 DOI: 10.1146/Annurev-Med-081117-041238 |
0.376 |
|
| 2018 |
Tahmasebi S, Khoutorsky A, Mathews MB, Sonenberg N. Translation deregulation in human disease. Nature Reviews. Molecular Cell Biology. PMID 30038383 DOI: 10.1038/S41580-018-0034-X |
0.413 |
|
| 2018 |
Moy JK, Khoutorsky A, Asiedu MN, Dussor G, Price TJ. eIF4E Phosphorylation InfluencesmRNA Translation in Mouse Dorsal Root Ganglion Neurons. Frontiers in Cellular Neuroscience. 12: 29. PMID 29467623 DOI: 10.3389/Fncel.2018.00029 |
0.388 |
|
| 2018 |
Jafarnejad SM, Chapat C, Matta-Camacho E, Gelbart IA, Hesketh GG, Arguello M, Garzia A, Kim SH, Attig J, Shapiro M, Morita M, Khoutorsky A, Alain T, Gkogkas C, Stern-Ginossar N, et al. Translational control of ERK signaling through miRNA/4EHP-directed silencing. Elife. 7. PMID 29412140 DOI: 10.7554/Elife.35034 |
0.712 |
|
| 2017 |
Martin LJ, Smith SB, Khoutorsky A, Magnussen CA, Samoshkin A, Sorge RE, Cho C, Yosefpour N, Sivaselvachandran S, Tohyama S, Cole T, Khuong TM, Mir E, Gibson DG, Wieskopf JS, et al. Epiregulin and EGFR interactions are involved in pain processing. The Journal of Clinical Investigation. PMID 28783046 DOI: 10.1172/Jci87406 |
0.679 |
|
| 2017 |
Moy JK, Khoutorsky A, Asiedu MN, Black BJ, Kuhn JL, Barragán-Iglesias P, Megat S, Burton MD, Burgos-Vega CC, Melemedjian OK, Boitano S, Vagner J, Gkogkas CG, Pancrazio JJ, Mogil JS, et al. The MNK - eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28674170 DOI: 10.1523/Jneurosci.0220-17.2017 |
0.719 |
|
| 2017 |
Gantois I, Khoutorsky A, Popic J, Aguilar-Valles A, Freemantle E, Cao R, Sharma V, Pooters T, Nagpal A, Skalecka A, Truong VT, Wiebe S, Groves IA, Jafarnejad SM, Chapat C, et al. Metformin ameliorates core deficits in a mouse model of fragile X syndrome. Nature Medicine. PMID 28504725 DOI: 10.1038/Nm.4335 |
0.763 |
|
| 2017 |
Tuttle AH, Tansley S, Dossett K, Tohyama S, Khoutorsky A, Maldonado-Bouchard S, Stein L, Gerstein L, Crawhall-Duk H, Pearl R, Sukosd M, Leger P, Hardt OM, Yachnin D, Austin JS, et al. Social propinquity in rodents as measured by tube cooccupancy differs between inbred and outbred genotypes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28484016 DOI: 10.1073/Pnas.1703477114 |
0.663 |
|
| 2016 |
Tahmasebi S, Jafarnejad SM, Tam IS, Gonatopoulos-Pournatzis T, Matta-Camacho E, Tsukumo Y, Yanagiya A, Li W, Atlasi Y, Caron M, Braunschweig U, Pearl D, Khoutorsky A, Gkogkas CG, Nadon R, et al. Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791185 DOI: 10.1073/Pnas.1615540113 |
0.712 |
|
| 2016 |
Khoutorsky A, Sorge RE, Prager-Khoutorsky M, Pawlowski SA, Longo G, Jafarnejad SM, Tahmasebi S, Martin LJ, Pitcher MH, Gkogkas CG, Sharif-Naeini R, Ribeiro-da-Silva A, Bourque CW, Cervero F, Mogil JS, et al. eIF2α phosphorylation controls thermal nociception. Proceedings of the National Academy of Sciences of the United States of America. PMID 27698114 DOI: 10.1073/Pnas.1614047113 |
0.701 |
|
| 2016 |
Skałecka A, Liszewska E, Bilinski R, Gkogkas C, Khoutorsky A, Malik AR, Sonenberg N, Jaworski J. mTOR kinase is needed for the development and stabilization of dendritic arbors in newly born olfactory bulb neurons. Developmental Neurobiology. PMID 27008592 DOI: 10.1002/Dneu.22392 |
0.677 |
|
| 2015 |
Khoutorsky A, Bonin RP, Sorge RE, Gkogkas CG, Pawlowski SA, Jafarnejad SM, Pitcher MH, Alain T, Perez-Sanchez J, Salter EW, Martin L, Ribeiro-da-Silva A, De Koninck Y, Cervero F, Mogil JS, et al. Translational control of nociception via 4E-binding protein 1. Elife. 4. PMID 26678009 DOI: 10.7554/Elife.12002 |
0.746 |
|
| 2015 |
Aguilar-Valles A, Matta-Camacho E, Khoutorsky A, Gkogkas C, Nader K, Lacaille JC, Sonenberg N. Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 11125-32. PMID 26245973 DOI: 10.1523/Jneurosci.4615-14.2015 |
0.733 |
|
| 2014 |
Gkogkas CG, Khoutorsky A, Cao R, Jafarnejad SM, Prager-Khoutorsky M, Giannakas N, Kaminari A, Fragkouli A, Nader K, Price TJ, Konicek BW, Graff JR, Tzinia AK, Lacaille JC, Sonenberg N. Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes. Cell Reports. 9: 1742-55. PMID 25466251 DOI: 10.1016/J.Celrep.2014.10.064 |
0.755 |
|
| 2014 |
Tahmasebi S, Alain T, Rajasekhar VK, Zhang JP, Prager-Khoutorsky M, Khoutorsky A, Dogan Y, Gkogkas CG, Petroulakis E, Sylvestre A, Ghorbani M, Assadian S, Yamanaka Y, Vinagolu-Baur JR, Teodoro JG, et al. Multifaceted regulation of somatic cell reprogramming by mRNA translational control. Cell Stem Cell. 14: 606-16. PMID 24630793 DOI: 10.1016/J.Stem.2014.02.005 |
0.715 |
|
| 2013 |
Graber TE, Hébert-Seropian S, Khoutorsky A, David A, Yewdell JW, Lacaille JC, Sossin WS. Reactivation of stalled polyribosomes in synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. 110: 16205-10. PMID 24043809 DOI: 10.1073/Pnas.1307747110 |
0.314 |
|
| 2013 |
Cao R, Robinson B, Xu H, Gkogkas C, Khoutorsky A, Alain T, Yanagiya A, Nevarko T, Liu AC, Amir S, Sonenberg N. Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling. Neuron. 79: 712-24. PMID 23972597 DOI: 10.1016/J.Neuron.2013.06.026 |
0.755 |
|
| 2013 |
Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, et al. Pharmacological brake-release of mRNA translation enhances cognitive memory. Elife. 2: e00498. PMID 23741617 DOI: 10.7554/Elife.00498 |
0.485 |
|
| 2013 |
Svitkin YV, Yanagiya A, Karetnikov AE, Alain T, Fabian MR, Khoutorsky A, Perreault S, Topisirovic I, Sonenberg N. Control of translation and miRNA-dependent repression by a novel poly(A) binding protein, hnRNP-Q. Plos Biology. 11: e1001564. PMID 23700384 DOI: 10.1371/Journal.Pbio.1001564 |
0.428 |
|
| 2013 |
Khoutorsky A, Yanagiya A, Gkogkas CG, Fabian MR, Prager-Khoutorsky M, Cao R, Gamache K, Bouthiette F, Parsyan A, Sorge RE, Mogil JS, Nader K, Lacaille JC, Sonenberg N. Control of synaptic plasticity and memory via suppression of poly(A)-binding protein. Neuron. 78: 298-311. PMID 23622065 DOI: 10.1016/J.Neuron.2013.02.025 |
0.757 |
|
| 2013 |
Melemedjian OK, Khoutorsky A, Sorge RE, Yan J, Asiedu MN, Valdez A, Ghosh S, Dussor G, Mogil JS, Sonenberg N, Price TJ. mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK. Pain. 154: 1080-91. PMID 23607966 DOI: 10.1016/J.Pain.2013.03.021 |
0.464 |
|
| 2013 |
Chaveroux C, Eichner LJ, Dufour CR, Shatnawi A, Khoutorsky A, Bourque G, Sonenberg N, Giguère V. Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver. Cell Metabolism. 17: 586-98. PMID 23562079 DOI: 10.1016/J.Cmet.2013.03.003 |
0.435 |
|
| 2013 |
Ran I, Gkogkas CG, Vasuta C, Tartas M, Khoutorsky A, Laplante I, Parsyan A, Nevarko T, Sonenberg N, Lacaille JC. Selective regulation of GluA subunit synthesis and AMPA receptor-mediated synaptic function and plasticity by the translation repressor 4E-BP2 in hippocampal pyramidal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1872-86. PMID 23365227 DOI: 10.1523/Jneurosci.3264-12.2013 |
0.741 |
|
| 2013 |
Gkogkas CG, Khoutorsky A, Ran I, Rampakakis E, Nevarko T, Weatherill DB, Vasuta C, Yee S, Truitt M, Dallaire P, Major F, Lasko P, Ruggero D, Nader K, Lacaille JC, et al. Autism-related deficits via dysregulated eIF4E-dependent translational control. Nature. 493: 371-7. PMID 23172145 DOI: 10.1038/Nature11628 |
0.748 |
|
| 2011 |
Melemedjian OK, Asiedu MN, Tillu DV, Sanoja R, Yan J, Lark A, Khoutorsky A, Johnson J, Peebles KA, Lepow T, Sonenberg N, Dussor G, Price TJ. Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain. Molecular Pain. 7: 70. PMID 21936900 DOI: 10.1186/1744-8069-7-70 |
0.486 |
|
| Show low-probability matches. |