Year |
Citation |
Score |
2022 |
Al-Zaid B, Chacko S, Ezeamuzie CI, Bünemann M, Krasel C, Karimian T, Lanzerstorfer P, Al-Sabah S. Differential effects of glucose-dependent insulinotropic polypeptide receptor/glucagon-like peptide-1 receptor heteromerization on cell signaling when expressed in HEK-293 cells. Pharmacology Research & Perspectives. 10: e01013. PMID 36177761 DOI: 10.1002/prp2.1013 |
0.504 |
|
2022 |
Ismaeil A, Babiker F, Al-Sabah S. Discrepancy between the Actions of Glucagon-like Peptide-1 Receptor Ligands in the Protection of the Heart against Ischemia Reperfusion Injury. Pharmaceuticals (Basel, Switzerland). 15. PMID 35745639 DOI: 10.3390/ph15060720 |
0.373 |
|
2020 |
Al-Sabah S, Adi L, Bünemann M, Krasel C. The Effect of Cell Surface Expression and Linker Sequence on the Recruitment of Arrestin to the GIP Receptor. Frontiers in Pharmacology. 11: 1271. PMID 32903502 DOI: 10.3389/Fphar.2020.01271 |
0.574 |
|
2020 |
Al-Zamel N, Al-Sabah S, Luqmani Y, Adi L, Chacko S, Schneider TD, Krasel C. Correction: Al-Zamel, N., et al. A Dual GLP-1/GIP Receptor Agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased Agonist at the GLP-1 Receptor. 2019, , 3532. International Journal of Molecular Sciences. 21. PMID 32397501 DOI: 10.3390/ijms21093357 |
0.41 |
|
2019 |
Al-Zamel N, Al-Sabah S, Luqmani Y, Adi L, Chacko S, Schneider TD, Krasel C. A Dual GLP-1/GIP Receptor Agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased Agonist at the GLP-1 Receptor. International Journal of Molecular Sciences. 20. PMID 31330984 DOI: 10.3390/ijms20143532 |
0.567 |
|
2016 |
Shaaban G, Oriowo M, Al-Sabah S. Rate of Homologous Desensitization and Internalization of the GLP-1 Receptor. Molecules (Basel, Switzerland). 22. PMID 28035964 DOI: 10.3390/molecules22010022 |
0.479 |
|
2015 |
Al-Sabah S. Molecular Pharmacology of the Incretin Receptors. Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre. 15-21. PMID 26111634 DOI: 10.1159/000433437 |
0.472 |
|
2015 |
Zindel D, Butcher AJ, Al-Sabah S, Lanzerstorfer P, Weghuber J, Tobin AB, Bünemann M, Krasel C. Engineered hyperphosphorylation of the β2-adrenoceptor prolongs arrestin-3 binding and induces arrestin internalization. Molecular Pharmacology. 87: 349-62. PMID 25425623 DOI: 10.1124/Mol.114.095422 |
0.529 |
|
2014 |
Al-Sabah S, Al-Fulaij M, Shaaban G, Ahmed HA, Mann RJ, Donnelly D, Bünemann M, Krasel C. The GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively. Plos One. 9: e106890. PMID 25191754 DOI: 10.1371/Journal.Pone.0106890 |
0.618 |
|
2014 |
Lampe M, Pierre F, Al-Sabah S, Krasel C, Merrifield CJ. Dual single-scission event analysis of constitutive transferrin receptor (TfR) endocytosis and ligand-triggered β2-adrenergic receptor (β2AR) or Mu-opioid receptor (MOR) endocytosis. Molecular Biology of the Cell. 25: 3070-80. PMID 25079691 DOI: 10.1091/mbc.E14-06-1112 |
0.498 |
|
2012 |
Markovic D, Holdich J, Al-Sabah S, Mistry R, Krasel C, Mahaut-Smith MP, Challiss RA. FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists. Plos One. 7: e29946. PMID 22272263 DOI: 10.1371/journal.pone.0029946 |
0.499 |
|
2010 |
Mann RJ, Al-Sabah S, de Maturana RL, Sinfield JK, Donnelly D. Functional coupling of Cys-226 and Cys-296 in the glucagon-like peptide-1 (GLP-1) receptor indicates a disulfide bond that is close to the activation pocket. Peptides. 31: 2289-93. PMID 20869417 DOI: 10.1016/j.peptides.2010.09.015 |
0.463 |
|
2010 |
McPherson J, Rivero G, Baptist M, Llorente J, Al-Sabah S, Krasel C, Dewey WL, Bailey CP, Rosethorne EM, Charlton SJ, Henderson G, Kelly E. μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization. Molecular Pharmacology. 78: 756-66. PMID 20647394 DOI: 10.1124/mol.110.066613 |
0.47 |
|
2008 |
Krasel C, Zabel U, Lorenz K, Reiner S, Al-Sabah S, Lohse MJ. Dual role of the beta2-adrenergic receptor C terminus for the binding of beta-arrestin and receptor internalization. The Journal of Biological Chemistry. 283: 31840-8. PMID 18801735 DOI: 10.1074/Jbc.M806086200 |
0.416 |
|
2004 |
Al-Sabah S, Donnelly D. The primary ligand-binding interaction at the GLP-1 receptor is via the putative helix of the peptide agonists. Protein and Peptide Letters. 11: 9-14. PMID 14965273 DOI: 10.2174/0929866043478365 |
0.794 |
|
2003 |
Al-Sabah S, Donnelly D. The positive charge at Lys-288 of the glucagon-like peptide-1 (GLP-1) receptor is important for binding the N-terminus of peptide agonists. Febs Letters. 553: 342-6. PMID 14572647 DOI: 10.1016/s0014-5793(03)01043-3 |
0.8 |
|
2003 |
Al-Sabah S, Donnelly D. A model for receptor-peptide binding at the glucagon-like peptide-1 (GLP-1) receptor through the analysis of truncated ligands and receptors. British Journal of Pharmacology. 140: 339-46. PMID 12970080 DOI: 10.1038/sj.bjp.0705453 |
0.809 |
|
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