Ruben Stepanyan - Publications

Affiliations: 
2006-2013 Physiology University of Kentucky, Lexington, KY 

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Manikandan M, Walker S, Deshmukh AR, Perea E, Wang D, Alagramam KN, Stepanyan R. Mitochondrial calcium uniporter is essential for hearing and hair cell preservation in congenic FVB/NJ mice. Scientific Reports. 11: 9660. PMID 33958614 DOI: 10.1038/s41598-021-88841-0  0.4
2020 Chen Z, Zhu S, Kindig K, Wang S, Chou SW, Davis RW, Dercoli MR, Weaver H, Stepanyan R, McDermott BM. Tmc proteins are essential for zebrafish hearing where Tmc1 is not obligatory. Human Molecular Genetics. PMID 32167554 DOI: 10.1093/Hmg/Ddaa045  0.405
2019 Gopal SR, Lee YT, Stepanyan R, McDermott BM, Alagramam KN. Unconventional secretory pathway activation restores hair cell mechanotransduction in an USH3A model. Proceedings of the National Academy of Sciences of the United States of America. PMID 31097578 DOI: 10.1073/Pnas.1817500116  0.423
2017 Vargo JW, Walker SN, Gopal SR, Deshmukh AR, McDermott BM, Alagramam KN, Stepanyan R. Inhibition of Mitochondrial Division Attenuates Cisplatin-Induced Toxicity in the Neuromast Hair Cells. Frontiers in Cellular Neuroscience. 11: 393. PMID 29311828 DOI: 10.3389/Fncel.2017.00393  0.349
2017 Chou SW, Chen Z, Zhu S, Davis RW, Hu J, Liu L, Fernando CA, Kindig K, Brown WC, Stepanyan R, McDermott BM. A molecular basis for water motion detection by the mechanosensory lateral line of zebrafish. Nature Communications. 8: 2234. PMID 29269857 DOI: 10.1038/S41467-017-01604-2  0.414
2017 Geng R, Omar A, Gopal SR, Chen DH, Stepanyan R, Basch ML, Dinculescu A, Furness DN, Saperstein D, Hauswirth W, Lustig LR, Alagramam KN. Modeling and Preventing Progressive Hearing Loss in Usher Syndrome III. Scientific Reports. 7: 13480. PMID 29044151 DOI: 10.1038/S41598-017-13620-9  0.422
2016 Hu J, Li B, Apisa L, Yu H, Entenman S, Xu M, Stepanyan R, Guan BJ, Müller U, Hatzoglou M, Zheng QY. ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23(erl/erl) mutant mice. Cell Death & Disease. 7: e2485. PMID 27882946 DOI: 10.1038/Cddis.2016.386  0.357
2015 Gopal SR, Chen DH, Chou SW, Zang J, Neuhauss SC, Stepanyan R, McDermott BM, Alagramam KN. Zebrafish Models for the Mechanosensory Hair Cell Dysfunction in Usher Syndrome 3 Reveal That Clarin-1 Is an Essential Hair Bundle Protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 10188-201. PMID 26180195 DOI: 10.1523/Jneurosci.1096-15.2015  0.389
2013 Indzhykulian AA, Stepanyan R, Nelina A, Spinelli KJ, Ahmed ZM, Belyantseva IA, Friedman TB, Barr-Gillespie PG, Frolenkov GI. Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells. Plos Biology. 11: e1001583. PMID 23776407 DOI: 10.1371/Journal.Pbio.1001583  0.655
2012 Szarama KB, Stepanyan R, Petralia RS, Gavara N, Frolenkov GI, Kelley MW, Chadwick RS. Fibroblast growth factor receptor 3 regulates microtubule formation and cell surface mechanical properties in the developing organ of Corti. Bioarchitecture. 2: 214-9. PMID 23267415 DOI: 10.4161/bioa.22332  0.641
2011 Stepanyan RS, Indzhykulian AA, Vélez-Ortega AC, Boger ET, Steyger PS, Friedman TB, Frolenkov GI. TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells. Journal of the Association For Research in Otolaryngology : Jaro. 12: 729-40. PMID 21879401 DOI: 10.1007/S10162-011-0288-X  0.645
2010 Kitajiri S, Sakamoto T, Belyantseva IA, Goodyear RJ, Stepanyan R, Fujiwara I, Bird JE, Riazuddin S, Riazuddin S, Ahmed ZM, Hinshaw JE, Sellers J, Bartles JR, Hammer JA, Richardson GP, et al. Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing. Cell. 141: 786-98. PMID 20510926 DOI: 10.1016/J.Cell.2010.03.049  0.684
2009 Belyantseva IA, Perrin BJ, Sonnemann KJ, Zhu M, Stepanyan R, McGee J, Frolenkov GI, Walsh EJ, Friderici KH, Friedman TB, Ervasti JM. Gamma-actin is required for cytoskeletal maintenance but not development. Proceedings of the National Academy of Sciences of the United States of America. 106: 9703-8. PMID 19497859 DOI: 10.1073/Pnas.0900221106  0.64
2009 Stepanyan R, Frolenkov GI. Fast adaptation and Ca2+ sensitivity of the mechanotransducer require myosin-XVa in inner but not outer cochlear hair cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4023-34. PMID 19339598 DOI: 10.1523/JNEUROSCI.4566-08.2009  0.718
2009 Novak P, Li C, Shevchuk AI, Stepanyan R, Caldwell M, Hughes S, Smart TG, Gorelik J, Ostanin VP, Lab MJ, Moss GW, Frolenkov GI, Klenerman D, Korchev YE. Nanoscale live-cell imaging using hopping probe ion conductance microscopy. Nature Methods. 6: 279-81. PMID 19252505 DOI: 10.1038/Nmeth.1306  0.604
2006 Stepanyan R, Belyantseva IA, Griffith AJ, Friedman TB, Frolenkov GI. Auditory mechanotransduction in the absence of functional myosin-XVa. The Journal of Physiology. 576: 801-8. PMID 16973713 DOI: 10.1113/jphysiol.2006.118547  0.702
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