cached image

Jan Wijnholds - Publications

Affiliations: 
Netherlands Institute for Neuroscience, Amsterdam-Zuidoost, Noord-Holland, Netherlands 
Area:
retinal degeneration
Website:
http://www.nin.knaw.nl/research_groups/wijnholds_group/jan_wijnholds

70/110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

PUBLICATION UPDATES TEMPORARILY DISABLED DURING DATABASE UPDATE, SORRY!

Year Citation  Score
2015 Ramkumar N, Harvey BM, Lee JD, Alcorn HL, Silva-Gagliardi NF, McGlade CJ, Bestor TH, Wijnholds J, Haltiwanger RS, Anderson KV. Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2. Plos Genetics. 11: e1005551. PMID 26496195 DOI: 10.1371/journal.pgen.1005551  0.72
2015 Zhao M, Andrieu-Soler C, Kowalczuk L, Paz Cortés M, Berdugo M, Dernigoghossian M, Halili F, Jeanny JC, Goldenberg B, Savoldelli M, El Sanharawi M, Naud MC, van Ijcken W, Pescini-Gobert R, Martinet D, ... ... Wijnholds J, et al. A new CRB1 rat mutation links Müller glial cells to retinal telangiectasia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6093-106. PMID 25878282 DOI: 10.1523/JNEUROSCI.3412-14.2015  0.72
2015 Pellissier LP, Quinn PM, Alves CH, Vos RM, Klooster J, Flannery JG, Heimel JA, Wijnholds J. Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models. Human Molecular Genetics. 24: 3104-18. PMID 25701872 DOI: 10.1093/hmg/ddv062  0.72
2014 Pellissier LP, Lundvig DM, Tanimoto N, Klooster J, Vos RM, Richard F, Sothilingam V, Garcia Garrido M, Le Bivic A, Seeliger MW, Wijnholds J. CRB2 acts as a modifying factor of CRB1-related retinal dystrophies in mice. Human Molecular Genetics. 23: 3759-71. PMID 24565864 DOI: 10.1093/hmg/ddu089  0.72
2014 Alves CH, Pellissier LP, Wijnholds J. The CRB1 and adherens junction complex proteins in retinal development and maintenance. Progress in Retinal and Eye Research. 40: 35-52. PMID 24508727 DOI: 10.1016/j.preteyeres.2014.01.001  0.72
2014 Alves CH, Pellissier LP, Vos RM, Garcia Garrido M, Sothilingam V, Seide C, Beck SC, Klooster J, Furukawa T, Flannery JG, Verhaagen J, Seeliger MW, Wijnholds J. Targeted ablation of Crb2 in photoreceptor cells induces retinitis pigmentosa. Human Molecular Genetics. 23: 3384-401. PMID 24493795 DOI: 10.1093/hmg/ddu048  0.72
2013 Pellissier LP, Alves CH, Quinn PM, Vos RM, Tanimoto N, Lundvig DM, Dudok JJ, Hooibrink B, Richard F, Beck SC, Huber G, Sothilingam V, Garcia Garrido M, Le Bivic A, Seeliger MW, ... Wijnholds J, et al. Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis. Plos Genetics. 9: e1003976. PMID 24339791 DOI: 10.1371/journal.pgen.1003976  0.72
2013 Alves CH, Bossers K, Vos RM, Essing AH, Swagemakers S, van der Spek PJ, Verhaagen J, Wijnholds J. Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background. Plos One. 8: e82532. PMID 24324803 DOI: 10.1371/journal.pone.0082532  0.72
2013 Dudok JJ, Sanz AS, Lundvig DM, Sothilingam V, Garrido MG, Klooster J, Seeliger MW, Wijnholds J. MPP3 regulates levels of PALS1 and adhesion between photoreceptors and Müller cells. Glia. 61: 1629-44. PMID 23893895 DOI: 10.1002/glia.22545  0.72
2013 Assémat E, Crost E, Ponserre M, Wijnholds J, Le Bivic A, Massey-Harroche D. The multi-PDZ domain protein-1 (MUPP-1) expression regulates cellular levels of the PALS-1/PATJ polarity complex. Experimental Cell Research. 319: 2514-25. PMID 23880463 DOI: 10.1016/j.yexcr.2013.07.011  0.72
2013 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J. MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8518-27. PMID 23658188 DOI: 10.1523/JNEUROSCI.5627-12.2013  0.72
2013 Alves CH, Sanz AS, Park B, Pellissier LP, Tanimoto N, Beck SC, Huber G, Murtaza M, Richard F, Sridevi Gurubaran I, Garcia Garrido M, Levelt CN, Rashbass P, Le Bivic A, Seeliger MW, ... Wijnholds J, et al. Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. Human Molecular Genetics. 22: 35-50. PMID 23001562 DOI: 10.1093/hmg/dds398  0.72
2011 Park B, Alves CH, Lundvig DM, Tanimoto N, Beck SC, Huber G, Richard F, Klooster J, Andlauer TF, Swindell EC, Jamrich M, Le Bivic A, Seeliger MW, Wijnholds J. PALS1 is essential for retinal pigment epithelium structure and neural retina stratification. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17230-41. PMID 22114289 DOI: 10.1523/JNEUROSCI.4430-11.2011  0.72
2010 Aartsen WM, van Cleef KW, Pellissier LP, Hoek RM, Vos RM, Blits B, Ehlert EM, Balaggan KS, Ali RR, Verhaagen J, Wijnholds J. GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors. Plos One. 5: e12387. PMID 20808778 DOI: 10.1371/journal.pone.0012387  0.72
2010 Kim S, Lehtinen MK, Sessa A, Zappaterra MW, Cho SH, Gonzalez D, Boggan B, Austin CA, Wijnholds J, Gambello MJ, Malicki J, LaMantia AS, Broccoli V, Walsh CA. The apical complex couples cell fate and cell survival to cerebral cortical development. Neuron. 66: 69-84. PMID 20399730 DOI: 10.1016/j.neuron.2010.03.019  0.72
2010 Jaissle GB, May CA, van de Pavert SA, Wenzel A, Claes-May E, Giessl A, Szurman P, Wolfrum U, Wijnholds J, Fischer MD, Fisher MD, Humphries P, Seeliger MW. Bone spicule pigment formation in retinitis pigmentosa: insights from a mouse model. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 248: 1063-70. PMID 20012642 DOI: 10.1007/s00417-009-1253-9  0.72
2009 Fischer MD, Huber G, Beck SC, Tanimoto N, Muehlfriedel R, Fahl E, Grimm C, Wenzel A, Remé CE, van de Pavert SA, Wijnholds J, Pacal M, Bremner R, Seeliger MW. Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography. Plos One. 4: e7507. PMID 19838301 DOI: 10.1371/journal.pone.0007507  0.72
2009 Stöhr H, Heisig JB, Benz PM, Schöberl S, Milenkovic VM, Strauss O, Aartsen WM, Wijnholds J, Weber BH, Schulz HL. TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6809-18. PMID 19474308 DOI: 10.1523/JNEUROSCI.5546-08.2009  0.72
2009 Aartsen WM, Arsanto JP, Chauvin JP, Vos RM, Versteeg I, Cardozo BN, Bivic AL, Wijnholds J. PSD95beta regulates plasma membrane Ca2+ pump localization at the photoreceptor synapse. Molecular and Cellular Neurosciences. 41: 156-65. PMID 19233278 DOI: 10.1016/j.mcn.2009.02.003  0.72
2008 de Wolf C, Jansen R, Yamaguchi H, de Haas M, van de Wetering K, Wijnholds J, Beijnen J, Borst P. Contribution of the drug transporter ABCG2 (breast cancer resistance protein) to resistance against anticancer nucleosides. Molecular Cancer Therapeutics. 7: 3092-102. PMID 18765824 DOI: 10.1158/1535-7163.MCT-08-0427  0.72
2007 van de Pavert SA, Sanz AS, Aartsen WM, Vos RM, Versteeg I, Beck SC, Klooster J, Seeliger MW, Wijnholds J. Crb1 is a determinant of retinal apical Müller glia cell features. Glia. 55: 1486-97. PMID 17705196 DOI: 10.1002/glia.20561  0.72
2007 van de Pavert SA, Meuleman J, Malysheva A, Aartsen WM, Versteeg I, Tonagel F, Kamphuis W, McCabe CJ, Seeliger MW, Wijnholds J. A single amino acid substitution (Cys249Trp) in Crb1 causes retinal degeneration and deregulates expression of pituitary tumor transforming gene Pttg1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 564-73. PMID 17234588 DOI: 10.1523/JNEUROSCI.3496-06.2007  0.72
2007 de Wolf CJ, Yamaguchi H, van der Heijden I, Wielinga PR, Hundscheid SL, Ono N, Scheffer GL, de Haas M, Schuetz JD, Wijnholds J, Borst P. cGMP transport by vesicles from human and mouse erythrocytes. The Febs Journal. 274: 439-50. PMID 17229149 DOI: 10.1111/j.1742-4658.2006.05591.x  0.72
2006 Richard M, Roepman R, Aartsen WM, van Rossum AG, den Hollander AI, Knust E, Wijnholds J, Cremers FP. Towards understanding CRUMBS function in retinal dystrophies. Human Molecular Genetics. 15: R235-43. PMID 16987889 DOI: 10.1093/hmg/ddl195  0.72
2006 Gavarini S, Bécamel C, Altier C, Lory P, Poncet J, Wijnholds J, Bockaert J, Marin P. Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability. Molecular Biology of the Cell. 17: 4619-31. PMID 16914526 DOI: 10.1091/mbc.E06-03-0218  0.72
2006 van Rossum AG, Aartsen WM, Meuleman J, Klooster J, Malysheva A, Versteeg I, Arsanto JP, Le Bivic A, Wijnholds J. Pals1/Mpp5 is required for correct localization of Crb1 at the subapical region in polarized Muller glia cells. Human Molecular Genetics. 15: 2659-72. PMID 16885194 DOI: 10.1093/hmg/ddl194  0.72
2006 Minich T, Riemer J, Schulz JB, Wielinga P, Wijnholds J, Dringen R. The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes. Journal of Neurochemistry. 97: 373-84. PMID 16539673 DOI: 10.1111/j.1471-4159.2006.03737.x  0.72
2006 Aartsen WM, Kantardzhieva A, Klooster J, van Rossum AG, van de Pavert SA, Versteeg I, Cardozo BN, Tonagel F, Beck SC, Tanimoto N, Seeliger MW, Wijnholds J. Mpp4 recruits Psd95 and Veli3 towards the photoreceptor synapse. Human Molecular Genetics. 15: 1291-302. PMID 16520334 DOI: 10.1093/hmg/ddl047  0.72
2006 Kantardzhieva A, Alexeeva S, Versteeg I, Wijnholds J. MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane. The Febs Journal. 273: 1152-65. PMID 16519681 DOI: 10.1111/j.1742-4658.2006.05140.x  0.72
2006 Zelcer N, van de Wetering K, de Waart R, Scheffer GL, Marschall HU, Wielinga PR, Kuil A, Kunne C, Smith A, van der Valk M, Wijnholds J, Elferink RO, Borst P. Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides. Journal of Hepatology. 44: 768-75. PMID 16225954 DOI: 10.1016/j.jhep.2005.07.022  0.72
2005 Seeliger MW, Beck SC, Pereyra-Muñoz N, Dangel S, Tsai JY, Luhmann UF, van de Pavert SA, Wijnholds J, Samardzija M, Wenzel A, Zrenner E, Narfström K, Fahl E, Tanimoto N, Acar N, et al. In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy. Vision Research. 45: 3512-9. PMID 16188288 DOI: 10.1016/j.visres.2005.08.014  0.72
2005 Michel D, Arsanto JP, Massey-Harroche D, Béclin C, Wijnholds J, Le Bivic A. PATJ connects and stabilizes apical and lateral components of tight junctions in human intestinal cells. Journal of Cell Science. 118: 4049-57. PMID 16129888 DOI: 10.1242/jcs.02528  0.72
2005 Wielinga P, Hooijberg JH, Gunnarsdottir S, Kathmann I, Reid G, Zelcer N, van der Born K, de Haas M, van der Heijden I, Kaspers G, Wijnholds J, Jansen G, Peters G, Borst P. The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates. Cancer Research. 65: 4425-30. PMID 15899835 DOI: 10.1158/0008-5472.CAN-04-2810  0.72
2004 Meuleman J, van de Pavert SA, Wijnholds J. Crumbs homologue 1 in polarity and blindness. Biochemical Society Transactions. 32: 828-30. PMID 15494026 DOI: 10.1042/BST0320828  0.72
2004 van de Pavert SA, Kantardzhieva A, Malysheva A, Meuleman J, Versteeg I, Levelt C, Klooster J, Geiger S, Seeliger MW, Rashbass P, Le Bivic A, Wijnholds J. Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure. Journal of Cell Science. 117: 4169-77. PMID 15316081 DOI: 10.1242/jcs.01301  0.72
2004 Borst P, Balzarini J, Ono N, Reid G, de Vries H, Wielinga P, Wijnholds J, Zelcer N. The potential impact of drug transporters on nucleoside-analog-based antiviral chemotherapy. Antiviral Research. 62: 1-7. PMID 15026196 DOI: 10.1016/j.antiviral.2003.11.002  0.72
2003 Hu X, Plomp AS, van Soest S, Wijnholds J, de Jong PT, Bergen AA. Pseudoxanthoma elasticum: a clinical, histopathological, and molecular update. Survey of Ophthalmology. 48: 424-38. PMID 12850230 DOI: 10.1016/S0039-6257(03)00053-5  0.72
2003 Reid G, Wielinga P, Zelcer N, van der Heijden I, Kuil A, de Haas M, Wijnholds J, Borst P. The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs. Proceedings of the National Academy of Sciences of the United States of America. 100: 9244-9. PMID 12835412 DOI: 10.1073/pnas.1033060100  0.72
2003 Reid G, Wielinga P, Zelcer N, De Haas M, Van Deemter L, Wijnholds J, Balzarini J, Borst P. Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5. Molecular Pharmacology. 63: 1094-103. PMID 12695538 DOI: 10.1124/mol.63.5.1094  0.72
2003 Hu X, Plomp A, Wijnholds J, Ten Brink J, van Soest S, van den Born LI, Leys A, Peek R, de Jong PT, Bergen AA. ABCC6/MRP6 mutations: further insight into the molecular pathology of pseudoxanthoma elasticum. European Journal of Human Genetics : Ejhg. 11: 215-24. PMID 12673275 DOI: 10.1038/sj.ejhg.5200953  0.72
2003 Wielinga PR, van der Heijden I, Reid G, Beijnen JH, Wijnholds J, Borst P. Characterization of the MRP4- and MRP5-mediated transport of cyclic nucleotides from intact cells. The Journal of Biological Chemistry. 278: 17664-71. PMID 12637526 DOI: 10.1074/jbc.M212723200  0.72
2002 Wielinga PR, Reid G, Challa EE, van der Heijden I, van Deemter L, de Haas M, Mol C, Kuil AJ, Groeneveld E, Schuetz JD, Brouwer C, De Abreu RA, Wijnholds J, Beijnen JH, Borst P. Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells. Molecular Pharmacology. 62: 1321-31. PMID 12435799 DOI: 10.1124/mol.62.6.1321  0.72
2002 ten Hove T, Drillenburg P, Wijnholds J, Te Velde AA, van Deventer SJ. Differential susceptibility of multidrug resistance protein-1 deficient mice to DSS and TNBS-induced colitis. Digestive Diseases and Sciences. 47: 2056-63. PMID 12353855 DOI: 10.1023/A:1019629013945  0.72
2002 Wijnholds J. Drug resistance caused by multidrug resistance-associated proteins. Novartis Foundation Symposium. 243: 69-79; discussion 80. PMID 11990783  0.72
2002 Scheffer GL, Hu X, Pijnenborg AC, Wijnholds J, Bergen AA, Scheper RJ. MRP6 (ABCC6) detection in normal human tissues and tumors. Laboratory Investigation; a Journal of Technical Methods and Pathology. 82: 515-8. PMID 11950908  0.72
2002 den Hollander AI, Ghiani M, de Kok YJ, Wijnholds J, Ballabio A, Cremers FP, Broccoli V. Isolation of Crb1, a mouse homologue of Drosophila crumbs, and analysis of its expression pattern in eye and brain. Mechanisms of Development. 110: 203-7. PMID 11744384 DOI: 10.1016/S0925-4773(01)00568-8  0.72
2001 Schultz MJ, Wijnholds J, Peppelenbosch MP, Vervoordeldonk MJ, Speelman P, van Deventer SJ, Borst P, van der Poll T. Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia. Journal of Immunology (Baltimore, Md. : 1950). 166: 4059-64. PMID 11238654  0.72
2000 Allen JD, Brinkhuis RF, van Deemter L, Wijnholds J, Schinkel AH. Extensive contribution of the multidrug transporters P-glycoprotein and Mrp1 to basal drug resistance. Cancer Research. 60: 5761-6. PMID 11059771  0.72
2000 Scheffer GL, Kool M, Heijn M, de Haas M, Pijnenborg AC, Wijnholds J, van Helvoort A, de Jong MC, Hooijberg JH, Mol CA, van der Linden M, de Vree JM, van der Valk P, Elferink RP, Borst P, et al. Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. Cancer Research. 60: 5269-77. PMID 11016657  0.72
2000 Borst P, Evers R, Kool M, Wijnholds J. A family of drug transporters: the multidrug resistance-associated proteins. Journal of the National Cancer Institute. 92: 1295-302. PMID 10944550  0.72
2000 Wijnholds J, Mol CA, van Deemter L, de Haas M, Scheffer GL, Baas F, Beijnen JH, Scheper RJ, Hatse S, De Clercq E, Balzarini J, Borst P. Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs. Proceedings of the National Academy of Sciences of the United States of America. 97: 7476-81. PMID 10840050 DOI: 10.1073/pnas.120159197  0.72
2000 Wijnholds J, deLange EC, Scheffer GL, van den Berg DJ, Mol CA, van der Valk M, Schinkel AH, Scheper RJ, Breimer DD, Borst P. Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier. The Journal of Clinical Investigation. 105: 279-85. PMID 10675353 DOI: 10.1172/JCI8267  0.72
1999 Borst P, Evers R, Kool M, Wijnholds J. The multidrug resistance protein family. Biochimica Et Biophysica Acta. 1461: 347-57. PMID 10581366 DOI: 10.1016/S0005-2736(99)00167-4  0.72
1999 van Helvoort A, de Brouwer A, Ottenhoff R, Brouwers JF, Wijnholds J, Beijnen JH, Rijneveld A, van der Poll T, van der Valk MA, Majoor D, Voorhout W, Wirtz KW, Elferink RP, Borst P. Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces. Proceedings of the National Academy of Sciences of the United States of America. 96: 11501-6. PMID 10500206 DOI: 10.1073/pnas.96.20.11501  0.72
1999 Allen JD, Brinkhuis RF, Wijnholds J, Schinkel AH. The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin. Cancer Research. 59: 4237-41. PMID 10485464  0.72
1998 Wijnholds J, Scheffer GL, van der Valk M, van der Valk P, Beijnen JH, Scheper RJ, Borst P. Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage. The Journal of Experimental Medicine. 188: 797-808. PMID 9730882 DOI: 10.1084/jem.188.5.797  0.72
1997 Evers R, Cnubben NH, Wijnholds J, van Deemter L, van Bladeren PJ, Borst P. Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1. Febs Letters. 419: 112-6. PMID 9426231 DOI: 10.1016/S0014-5793(97)01442-7  0.72
1997 Wijnholds J, Evers R, van Leusden MR, Mol CA, Zaman GJ, Mayer U, Beijnen JH, van der Valk M, Krimpenfort P, Borst P. Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein. Nature Medicine. 3: 1275-9. PMID 9359705 DOI: 10.1038/NM1197-1275  0.72
1995 Smidt MP, Russchen B, Snippe L, Wijnholds J, Ab G. Cloning and characterisation of a nuclear, site specific ssDNA binding protein. Nucleic Acids Research. 23: 2389-95. PMID 7630716  0.72
1995 Wijnholds J, Chowdhury K, Wehr R, Gruss P. Segment-specific expression of the neuronatin gene during early hindbrain development. Developmental Biology. 171: 73-84. PMID 7556909 DOI: 10.1006/dbio.1995.1261  0.72
1994 Smidt MP, Wijnholds J, Snippe L, van Keulen G, Ab G. Binding of a bZip protein to the estrogen-inducible apoVLDL II promoter. Biochimica Et Biophysica Acta. 1219: 115-20. PMID 8086448 DOI: 10.1016/0167-4781(94)90253-4  0.72
1994 Chalepakis G, Wijnholds J, Gruss P. Pax-3-DNA interaction: flexibility in the DNA binding and induction of DNA conformational changes by paired domains. Nucleic Acids Research. 22: 3131-7. PMID 8065927  0.72
1994 Chalepakis G, Wijnholds J, Giese P, Schachner M, Gruss P. Characterization of Pax-6 and Hoxa-1 binding to the promoter region of the neural cell adhesion molecule L1. Dna and Cell Biology. 13: 891-900. PMID 7917011  0.72
1993 Wijnholds J, Philipsen S, Pruzina S, Fraser P, Grosveld F, Ab G. Estrogen-inducible and liver-specific expression of the chicken Very Low Density Apolipoprotein II gene locus in transgenic mice. Nucleic Acids Research. 21: 1629-35. PMID 8479914  0.72
1993 Chalepakis G, Stoykova A, Wijnholds J, Tremblay P, Gruss P. Pax: gene regulators in the developing nervous system. Journal of Neurobiology. 24: 1367-84. PMID 8228963 DOI: 10.1002/neu.480241009  0.72
1992 Calkhoven CF, Ab G, Wijnholds J. c/CEPB, a chicken transcription factor of the leucine-zipper C/EBP family [corrected]. Nucleic Acids Research. 20: 4093. PMID 1508696 DOI: 10.1093/nar/20.23.6440  0.72
1991 Wijnholds J, Muller E, Ab G. Oestrogen facilitates the binding of ubiquitous and liver-enriched nuclear proteins to the apoVLDL II promoter in vivo. Nucleic Acids Research. 19: 33-41. PMID 2011511  0.72
1991 Beekman JM, Wijnholds J, Schippers IJ, Pot W, Gruber M, Ab G. Regulatory elements and DNA-binding proteins mediating transcription from the chicken very-low-density apolipoprotein II gene. Nucleic Acids Research. 19: 5371-7. PMID 1923821 DOI: 10.1093/nar/19.19.5371  0.72
1988 Wijnholds J, Philipsen JN, Ab G. Tissue-specific and steroid-dependent interaction of transcription factors with the oestrogen-inducible apoVLDL II promoter in vivo. The Embo Journal. 7: 2757-63. PMID 3181140  0.72
1986 Smit MJ, Wijnholds J, Duursma AM, Bouma JM, Gruber M. Plasma clearance of mitochondrial aspartate aminotransferase in the rat: competition with mitochondrial malate dehydrogenase. Biomedica Biochimica Acta. 45: 1557-61. PMID 3579876  0.72
Low-probability matches
2014 Pellissier LP, Hoek RM, Vos RM, Aartsen WM, Klimczak RR, Hoyng SA, Flannery JG, Wijnholds J. Specific tools for targeting and expression in Müller glial cells. Molecular Therapy. Methods & Clinical Development. 1: 14009. PMID 26015954 DOI: 10.1038/mtm.2014.9  0.16
2018 Quinn PM, Mulder AA, Henrique Alves C, Desrosiers M, Vries SI, Klooster J, Dalkara D, Koster AJ, Jost CR, Wijnholds J. Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype. Human Molecular Genetics. PMID 30239717 DOI: 10.1093/hmg/ddy337  0.12
2018 Quinn PM, Alves CH, Klooster J, Wijnholds J. CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function. Human Molecular Genetics. PMID 29893966 DOI: 10.1093/hmg/ddy194  0.12
2005 Kantardzhieva A, Gosens I, Alexeeva S, Punte IM, Versteeg I, Krieger E, Neefjes-Mol CA, den Hollander AI, Letteboer SJ, Klooster J, Cremers FP, Roepman R, Wijnholds J. MPP5 recruits MPP4 to the CRB1 complex in photoreceptors. Investigative Ophthalmology & Visual Science. 46: 2192-201. PMID 15914641 DOI: 10.1167/iovs.04-1417  0.01
2021 Buck TM, Vos RM, Alves CH, Wijnholds J. AAV- protects against vision loss in an inducible retinitis pigmentosa mouse model. Molecular Therapy. Methods & Clinical Development. 20: 423-441. PMID 33575434 DOI: 10.1016/j.omtm.2020.12.012  0.04
2021 Talib M, van Schooneveld MJ, Wijnholds J, van Genderen MM, Schalij-Delfos NE, Talsma HE, Florijn RJ, Ten Brink JB, Cremers FPM, Thiadens AAHJ, van den Born LI, Hoyng CB, Meester-Smoor MA, Bergen AA, Boon CJF. Defining inclusion criteria and endpoints for clinical trials: a prospective cross-sectional study in CRB1-associated retinal dystrophies. Acta Ophthalmologica. PMID 33528094 DOI: 10.1111/aos.14597  0.04
2019 Quinn PM, Buck TM, Mulder AA, Ohonin C, Alves CH, Vos RM, Bialecka M, van Herwaarden T, van Dijk EHC, Talib M, Freund C, Mikkers HMM, Hoeben RC, Goumans MJ, Boon CJF, ... ... Wijnholds J, et al. Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5. Stem Cell Reports. PMID 30956116 DOI: 10.1016/j.stemcr.2019.03.002  0.04
2018 Talib M, van Schooneveld MJ, Van Cauwenbergh C, Wijnholds J, Ten Brink JB, Florijn RJ, Schalij-Delfos NE, Dagnelie G, van Genderen MM, De Baere E, Meester-Smoor MA, De Zaeytijd J, Cremers FPM, van den Born LI, Thiadens AA, et al. The Spectrum of Structural and Functional Abnormalities in Female Carriers of Pathogenic Variants in the RPGR Gene. Investigative Ophthalmology & Visual Science. 59: 4123-4133. PMID 30105367 DOI: 10.1167/iovs.17-23453  0.04
2018 Talib M, van Schooneveld MJ, Thiadens AA, Fiocco M, Wijnholds J, Florijn RJ, Schalij-Delfos NE, van Genderen MM, Putter H, Cremers FPM, Dagnelie G, Ten Brink JB, Klaver CCW, van den Born LI, Hoyng CB, et al. CLINICAL AND GENETIC CHARACTERISTICS OF MALE PATIENTS WITH RPGR-ASSOCIATED RETINAL DYSTROPHIES: A Long-Term Follow-up Study. Retina (Philadelphia, Pa.). PMID 29528978 DOI: 10.1097/IAE.0000000000002125  0.04
2018 Buck TM, Pellissier LP, Vos RM, van Dijk EHC, Boon CJF, Wijnholds J. AAV Serotype Testing on Cultured Human Donor Retinal Explants. Methods in Molecular Biology (Clifton, N.J.). 1715: 275-288. PMID 29188521 DOI: 10.1007/978-1-4939-7522-8_20  0.04
2021 Möller-Kerutt A, Rodriguez-Gatica JE, Wacker K, Bhatia R, Siebrasse JP, Boon N, Van Marck V, Boor P, Kubitscheck U, Wijnholds J, Pavenstädt H, Weide T. Crumbs2 Is an Essential Slit Diaphragm Protein of the Renal Filtration Barrier. Journal of the American Society of Nephrology : Jasn. PMID 33687977 DOI: 10.1681/ASN.2020040501  0.01
2020 Gallego C, Gonçalves MAFV, Wijnholds J. Novel Therapeutic Approaches for the Treatment of Retinal Degenerative Diseases: Focus on CRISPR/Cas-Based Gene Editing. Frontiers in Neuroscience. 14: 838. PMID 32973430 DOI: 10.3389/fnins.2020.00838  0.01
2020 Boon N, Wijnholds J, Pellissier LP. Research Models and Gene Augmentation Therapy for Retinal Dystrophies. Frontiers in Neuroscience. 14: 860. PMID 32922261 DOI: 10.3389/fnins.2020.00860  0.01
2020 Buck TM, Wijnholds J. Recombinant Adeno-Associated Viral Vectors (rAAV)-Vector Elements in Ocular Gene Therapy Clinical Trials and Transgene Expression and Bioactivity Assays. International Journal of Molecular Sciences. 21. PMID 32545533 DOI: 10.3390/ijms21124197  0.01
2020 Nguyen XT, Talib M, van Cauwenbergh C, van Schooneveld MJ, Fiocco M, Wijnholds J, Ten Brink JB, Florijn RJ, Schalij-Delfos NE, Dagnelie G, van Genderen MM, de Baere E, Meester-Smoor MA, De Zaeytijd J, Balikova I, et al. CLINICAL CHARACTERISTICS AND NATURAL HISTORY OF RHO-ASSOCIATED RETINITIS PIGMENTOSA: A Long-Term Follow-Up Study. Retina (Philadelphia, Pa.). PMID 32301896 DOI: 10.1097/IAE.0000000000002808  0.01
2020 Tait C, Chinnaiya K, Manning E, Murtaza M, Ashton JP, Furley N, Hill CJ, Alves CH, Wijnholds J, Erdmann KS, Furley A, Rashbass P, Das RM, Storey KG, Placzek M. Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal. Plos Biology. 18: e3000470. PMID 32150534 DOI: 10.1371/journal.pbio.3000470  0.01
2020 Nguyen XT, Talib M, van Schooneveld MJ, Brinks J, Ten Brink J, Florijn RJ, Wijnholds J, Verdijk RM, Bergen AA, Boon CJF. -Associated Dystrophies: Clinical, Genetic, and Histopathological Features. International Journal of Molecular Sciences. 21. PMID 32012938 DOI: 10.3390/ijms21030835  0.01
2019 Alves CH, Wijnholds J. Microglial Cell Dysfunction in CRB1-Associated Retinopathies. Advances in Experimental Medicine and Biology. 1185: 159-163. PMID 31884605 DOI: 10.1007/978-3-030-27378-1_26  0.01
2019 Quinn PMJ, Wijnholds J. Retinogenesis of the Human Fetal Retina: An Apical Polarity Perspective. Genes. 10. PMID 31795518 DOI: 10.3390/genes10120987  0.01
2019 Alves CH, Boon N, Mulder AA, Koster AJ, Jost CR, Wijnholds J. CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity. International Journal of Molecular Sciences. 20. PMID 31438467 DOI: 10.3390/ijms20174069  0.01
2019 Wijnholds J. "Basal Cell Migration" in Regeneration of the Corneal Wound-Bed. Stem Cell Reports. 12: 3-5. PMID 30629939 DOI: 10.1016/j.stemcr.2018.12.009  0.01
2018 Quinn PM, Buck TM, Ohonin C, Mikkers HMM, Wijnholds J. Production of iPS-Derived Human Retinal Organoids for Use in Transgene Expression Assays. Methods in Molecular Biology (Clifton, N.J.). 1715: 261-273. PMID 29188520 DOI: 10.1007/978-1-4939-7522-8_19  0.01
2018 Alves CH, Wijnholds J. AAV Gene Augmentation Therapy for CRB1-Associated Retinitis Pigmentosa. Methods in Molecular Biology (Clifton, N.J.). 1715: 135-151. PMID 29188511 DOI: 10.1007/978-1-4939-7522-8_10  0.01
2017 Dudok JJ, Leonards PEG, Wijnholds J. Genetic and Molecular Approaches to Study Neuronal Migration in the Developing Cerebral Cortex. Brain Sciences. 7. PMID 28475113 DOI: 10.3390/brainsci7050053  0.01
2017 Quinn PM, Pellissier LP, Wijnholds J. The CRB1 Complex: Following the Trail of Crumbs to a Feasible Gene Therapy Strategy. Frontiers in Neuroscience. 11: 175. PMID 28424578 DOI: 10.3389/fnins.2017.00175  0.01
2017 Talib M, van Schooneveld MJ, van Genderen MM, Wijnholds J, Florijn RJ, Ten Brink JB, Schalij-Delfos NE, Dagnelie G, Cremers FP, Wolterbeek R, Fiocco M, Thiadens AA, Hoyng CB, Klaver CC, Bergen AA, et al. Genotypic and Phenotypic Characteristics of CRB1-Associated Retinal Dystrophies: A Long-Term Follow-up Study. Ophthalmology. PMID 28341475 DOI: 10.1016/j.ophtha.2017.01.047  0.01
2016 Ramkumar N, Omelchenko T, Silva-Gagliardi NF, McGlade CJ, Wijnholds J, Anderson KV. Crumbs2 promotes cell ingression during the epithelial-to-mesenchymal transition at gastrulation. Nature Cell Biology. PMID 27870829 DOI: 10.1038/ncb3442  0.01
2016 Dudok JJ, Murtaza M, Alves CH, Rashbass P, Wijnholds J. Crumbs 2 prevents cortical abnormalities in mouse dorsal telencephalon. Neuroscience Research. PMID 26802325 DOI: 10.1016/j.neures.2016.01.001  0.01
2010 Jaissle GB, Albrecht May C, van de Pavert SA, Wenzel A, Claes-May E, Gießl A, Szurman P, Wolfrum U, Wijnholds J, Fischer MD, Humphries P, Seeliger MW. Erratum to: Bone spicule pigment formation in retinitis pigmentosa: insights from a mouse model Graefe's Archive For Clinical and Experimental Ophthalmology. 248: 1365-1365. DOI: 10.1007/s00417-010-1357-2  0.01
1998 Rijstenbil JW, Haritonidis S, Malea P, Seferlis M, Wijnholds JA. Thiol pools and glutathione redox ratios as possible indicators of copper toxicity in the green macroalgae Enteromorpha spp. from the Scheldt Estuary (SW Netherlands, Belgium) and Thermaikos Gulf (Greece, N Aegean Sea) Hydrobiologia. 385: 171-181. DOI: 10.1023/A:1003502428466  0.01
1998 Rijstenbil JW, Dehairs F, Ehrlich R, Wijnholds JA. Effect of the nitrogen status on copper accumulation and pools of metal- binding peptides in the planktonic diatom Thalassiosira pseudonana Aquatic Toxicology. 42: 187-209. DOI: 10.1016/S0166-445X(97)00091-X  0.01
1996 Rijstenbil JW, Wijnholds JA. HPLC analysis of nonprotein thiols in planktonic diatoms: Pool size, redox state and response to copper and cadmium exposure Marine Biology. 127: 45-54.  0.01
1994 Rijstenbil JW, Sandee A, Van Drie J, Wijnholds JA. Interaction of toxic trace metals and mechanisms of detoxification in the planktonic diatoms Ditylum brightwellii and Thalassiosira pseudonana. Fems Microbiology Reviews. 14: 387-96. PMID 7917426  0.01
1994 Rijstenbil JW, Derksen JWM, Gerringa LJA, Poortvliet TCW, Sandee A, van den Berg M, van Drie J, Wijnholds JA. Oxidative stress induced by copper: defense and damage in the marine planktonic diatom Ditylum brightwellii, grown in continuous cultures with high and low zinc levels Marine Biology. 119: 583-590. DOI: 10.1007/BF00354321  0.01
1994 Haritonidis S, Rijstenbil JW, Malea P, van Drie J, Wijnholds JA. Trace metal interactions in the macroalga Enteromorpha prolifera (O. F. Müller) J.Ag., grown in water of the Scheldt estuary (Belgium & SW Netherlands), in response to cadmium exposure Biometals. 7: 61-66. DOI: 10.1007/BF00205196  0.01
1993 Rijstenbil JW, Haritonidis S, van Drie J, Malea P, Wijnholds JA. Interactions of copper with trace metals and thiols in the macro-algae Enteromorpha prolifera (O.F.Müll)J.Ag., grown in water of the Scheldt Estuary (Belgium and S.W. Netherlands) Science of the Total Environment. 134: 539-549. DOI: 10.1016/S0048-9697(05)80056-7  0.01
1991 Rijstenbil JW, Wijnholds JA. Copper toxicity and adaptation in the marine diatom Ditylum brightwellii Comparative Biochemistry and Physiology. Part C, Comparative. 100: 147-150. DOI: 10.1016/0742-8413(91)90142-G  0.01
1991 Rijstenbil JW, Merks AGA, Peene J, Poortvliet TCW, Wijnholds JA. Phytoplankton composition and spatial distribution of copper and zinc in the Fal Estuary (Cornwall, UK) Hydrobiological Bulletin. 25: 37-43. DOI: 10.1007/BF02259587  0.01
1989 Rijstenbil JW, Wijnholds JA, Sinke JJ. Implications of salinity fluctuation for growth and nitrogen metabolism of the marine diatom Ditylum brightwellii in comparison with Skeletonema costatum Marine Biology. 101: 131-141. DOI: 10.1007/BF00393486  0.01
1989 Rijstenbil JW, Mur LR, Wijnholds JJ, Sinke JJ. Impact of a temporal salinity decrease on growth and nitrogen metabolism of the marine diatom Skeletonema costatum in continuous cultures Marine Biology. 101: 121-129. DOI: 10.1007/BF00393485  0.01
Hide low-probability matches.