Keary Mark Engle, Ph.D., D.Phil. - Publications

Affiliations: 
Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
organic synthesis, organometallics, catalysis
Website:
www.englelab.com

122 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rubel CZ, He WJ, Wisniewski SR, Engle KM. Benchtop Nickel Catalysis Invigorated by Electron-Deficient Diene Ligands. Accounts of Chemical Research. PMID 38236260 DOI: 10.1021/acs.accounts.3c00638  0.32
2024 Laudadio G, Neigenfind P, Péter Á, Rubel CZ, Emmanuel MA, Oderinde MS, El-Hayek Ewing T, Palkowitz MD, Sloane JL, Gillman KW, Ridge D, Mandler MD, Bolduc PN, Nicastri MC, Zhang B, ... ... Engle KM, et al. Nickel-Electrocatalytic Decarboxylative Arylation to Access Quaternary Centers. Angewandte Chemie (International Ed. in English). e202314617. PMID 38181042 DOI: 10.1002/anie.202314617  0.313
2023 Rubel CZ, Cao Y, El-Hayek Ewing T, Laudadio G, Beutner GL, Wisniewski SR, Wu X, Baran PS, Vantourout JC, Engle KM. Electroreductive Synthesis of Nickel(0) Complexes. Angewandte Chemie (International Ed. in English). e202311557. PMID 37984444 DOI: 10.1002/anie.202311557  0.308
2023 Hwang Y, Wisniewski SR, Engle KM. Ligand-Enabled Carboamidation of Unactivated Alkenes through Enhanced Organonickel Electrophilicity. Journal of the American Chemical Society. 145: 25293-25303. PMID 37938051 DOI: 10.1021/jacs.3c08855  0.367
2023 Ni HQ, Dai JC, Yang S, Loach RP, Chuba MD, McAlpine IJ, Engle KM. Catalytic σ-Bond Annulation with Ambiphilic Organohalides Enabled by β-X Elimination. Angewandte Chemie (International Ed. in English). e202306581. PMID 37306958 DOI: 10.1002/anie.202306581  0.343
2023 Ni HQ, Karunananda MK, Zeng T, Yang S, Liu Z, Houk KN, Liu P, Engle KM. Redox-Paired Alkene Difunctionalization Enables Skeletally Divergent Synthesis. Journal of the American Chemical Society. PMID 37220422 DOI: 10.1021/jacs.3c03274  0.808
2023 Simlandy AK, Alturaifi TM, Nguyen JM, Oxtoby LJ, Wong QN, Chen JS, Liu P, Engle KM. Enantioselective Hydroalkenylation and Hydroalkynylation of Alkenes Enabled by a Transient Directing Group: Catalyst Generality through Rigidification. Angewandte Chemie (International Ed. in English). e202304013. PMID 37141510 DOI: 10.1002/anie.202304013  0.829
2022 Gao Y, Kim N, Mendoza SD, Yazdani S, Faria-Vieira A, Liu M, Kendrick A, Grotjahn DB, Bertrand G, Jazzar R, Engle KM. (CAAC)Copper Catalysis Enables Regioselective Three-Component Carboboration of Terminal Alkynes. Acs Catalysis. 12: 7243-7247. PMID 37143933 DOI: 10.1021/acscatal.2c00614  0.389
2022 Tran VT, Kim N, Rubel CZ, Wu X, Kang T, Jankins TC, Li ZQ, Joannou MV, Ayers S, Gembicky M, Bailey J, Sturgell EJ, Sanchez BB, Chen JS, Lin S, ... ... Engle KM, et al. Structurally Diverse Bench-Stable Nickel(0) Pre-Catalysts: A Practical Toolkit for In Situ Ligation Protocols. Angewandte Chemie (International Ed. in English). PMID 36524997 DOI: 10.1002/anie.202211794  0.332
2022 Apolinar O, Kang T, Alturaifi TM, Bedekar PG, Rubel CZ, Derosa J, Sanchez BB, Wong QN, Sturgell EJ, Chen JS, Wisniewski SR, Liu P, Engle KM. Three-Component Asymmetric Ni-Catalyzed 1,2-Dicarbofunctionalization of Unactivated Alkenes via Stereoselective Migratory Insertion. Journal of the American Chemical Society. PMID 36222701 DOI: 10.1021/jacs.2c06636  0.731
2022 Liu Z, Oxtoby LJ, Sun J, Li ZQ, Kim N, Davies GHM, Engle KM. A Sterically Tuned Directing Auxiliary Promotes Catalytic 1,2-Carbofluorination of Alkenyl Carbonyl Compounds. Angewandte Chemie (International Ed. in English). PMID 36221812 DOI: 10.1002/anie.202214153  0.371
2022 Liu M, Sun J, Zhang T, Ding Y, Han YQ, Martín-Montero R, Lan Y, Shi BF, Engle KM. Regio- and Stereoselective 1,2-Oxyhalogenation of Non-Conjugated Alkynes via Directed Nucleopalladation: Catalytic Access to Tetrasubstituted Alkenes. Angewandte Chemie (International Ed. in English). e202209099. PMID 36082442 DOI: 10.1002/anie.202209099  0.583
2022 Li ZQ, He WJ, Ni HQ, Engle KM. Directed, nickel-catalyzed 1,2-alkylsulfenylation of alkenyl carbonyl compounds. Chemical Science. 13: 6567-6572. PMID 35756518 DOI: 10.1039/d2sc01563c  0.352
2022 Jankins TC, Bell WC, Zhang Y, Qin ZY, Chen JS, Gembicky M, Liu P, Engle KM. Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes. Nature Chemistry. 14: 632-639. PMID 35655006 DOI: 10.1038/s41557-022-00951-y  0.353
2022 Liu M, Sun J, Erbay T, Ni HQ, Martín-Montero R, Liu P, Engle KM. Pd(II)-Catalyzed C(alkenyl)-H Activation Facilitated by a Transient Directing Group. Angewandte Chemie (International Ed. in English). PMID 35467792 DOI: 10.1002/anie.202203624  0.447
2022 Li ZQ, Cao Y, Kang T, Engle KM. Electrophilic Sulfur Reagent Design Enables Directed -Carbosulfenylation of Unactivated Alkenes. Journal of the American Chemical Society. PMID 35436110 DOI: 10.1021/jacs.1c13252  0.393
2021 Liu B, Romine AM, Rubel CZ, Engle KM, Shi BF. Transition-Metal-Catalyzed, Coordination-Assisted Functionalization of Nonactivated C(sp)-H Bonds. Chemical Reviews. PMID 34714620 DOI: 10.1021/acs.chemrev.1c00519  0.52
2021 Li ZQ, Apolinar O, Deng R, Engle KM. Directed Markovnikov hydroarylation and hydroalkenylation of alkenes under nickel catalysis. Chemical Science. 12: 11038-11044. PMID 34522301 DOI: 10.1039/d1sc03121j  0.424
2021 Jankins TC, Martin-Montero R, Cooper P, Martin R, Engle KM. Low-Valent Tungsten Catalysis Enables Site-Selective Isomerization-Hydroboration of Unactivated Alkenes. Journal of the American Chemical Society. 143: 14981-14986. PMID 34498848 DOI: 10.1021/jacs.1c07162  0.354
2021 Romine AM, Demer MJ, Gembicky M, Rheingold AL, Engle KM. Ligand Rearrangement Leads to Tetrahydrothiophene-Functionalized -Heterocyclic Carbene Palladium(II) Complexes. Organometallics. 40: 2311-2319. PMID 34433997 DOI: 10.1021/acs.organomet.1c00041  0.325
2021 Matsuura R, Karunananda MK, Liu M, Nguyen N, Blackmond DG, Engle KM. Mechanistic Studies of Pd(II)-Catalyzed / Isomerization of Unactivated Alkenes: Evidence for a Monometallic Nucleopalladation Pathway. Acs Catalysis. 11: 4239-4246. PMID 34422450 DOI: 10.1021/acscatal.1c00783  0.785
2021 Ni HQ, Li ZQ, Tran VT, Engle KM. Modular synthesis of non-conjugated -(quinolin-8-yl) alkenyl amides via cross-metathesis. Tetrahedron. 93. PMID 34393281 DOI: 10.1016/j.tet.2021.132279  0.366
2021 Kleinmans R, Apolinar O, Derosa J, Karunananda MK, Li ZQ, Tran VT, Wisniewski SR, Engle KM. Ni-Catalyzed 1,2-Diarylation of Alkenyl Ketones: A Comparative Study of Carbonyl-Directed Reaction Systems. Organic Letters. PMID 34213351 DOI: 10.1021/acs.orglett.1c01447  0.837
2021 Gao Y, Yazdani S, Kendrick A, Junor GP, Kang T, Grotjahn DB, Bertrand G, Jazzar R, Engle KM. Cyclic(Alkyl)(Amino)Carbene Ligands Enable Cu-Catalyzed Markovnikov Protoboration and Protosilylation of Terminal Alkynes: A Versatile Portal to Functionalized Alkenes. Angewandte Chemie (International Ed. in English). PMID 34159696 DOI: 10.1002/anie.202106107  0.423
2021 Liu Z, Oxtoby LJ, Liu M, Li ZQ, Tran VT, Gao Y, Engle KM. A Transient Directing Group Strategy Enables Enantioselective Multicomponent Organofluorine Synthesis. Journal of the American Chemical Society. PMID 34077182 DOI: 10.1021/jacs.1c03178  0.335
2021 Liu M, Tang T, Apolinar O, Matsuura R, Busacca CA, Qu B, Fandrick DR, Zatolochnaya OV, Senanayake CH, Song JJ, Engle KM. Atom-Economical Cross-Coupling of Internal and Terminal Alkynes to Access 1,3-Enynes. Journal of the American Chemical Society. PMID 33683868 DOI: 10.1021/jacs.0c12565  0.458
2020 Wang X, Li ZQ, Mai BK, Gurak JA, Xu JE, Tran VT, Ni HQ, Liu Z, Liu Z, Yang KS, Xiang R, Liu P, Engle KM. Controlling cyclization pathways in palladium(ii)-catalyzed intramolecular alkene hydro-functionalization substrate directivity. Chemical Science. 11: 11307-11314. PMID 35382446 DOI: 10.1039/d0sc03409f  0.83
2020 Derosa J, Apolinar O, Kang T, Tran VT, Engle KM. Recent developments in nickel-catalyzed intermolecular dicarbofunctionalization of alkenes. Chemical Science. 11: 4287-4296. PMID 34122886 DOI: 10.1039/c9sc06006e  0.677
2020 Kang T, Erbay TG, Xu KL, Gallego GM, Burtea A, Nair SK, Patman RL, Zhou R, Sutton SC, McAlpine IJ, Liu P, Engle KM. Multifaceted Substrate-Ligand Interactions Promote the Copper-Catalyzed Hydroboration of Benzylidenecyclobutanes and Related Compounds. Acs Catalysis. 10: 13075-13083. PMID 33791144 DOI: 10.1021/acscatal.0c03622  0.388
2020 Liu Z, Gao Y, Zeng T, Engle KM. Transition-Metal-Catalyzed 1,2-Carboboration of Alkenes: Strategies, Mechanisms, and Stereocontrol. Israel Journal of Chemistry. 60: 219-229. PMID 33785969 DOI: 10.1002/ijch.201900087  0.414
2020 Ni HQ, Kevlishvili I, Bedekar PG, Barber JS, Yang S, Tran-Dubé M, Romine AM, Lu HX, McAlpine IJ, Liu P, Engle KM. Anti-selective [3+2] (Hetero)annulation of non-conjugated alkenes via directed nucleopalladation. Nature Communications. 11: 6432. PMID 33353940 DOI: 10.1038/s41467-020-20182-4  0.39
2020 Li ZQ, Fu Y, Deng R, Tran VT, Gao Y, Liu P, Engle KM. Ligand-Controlled Regiodivergence in Nickel-Catalyzed Hydroarylation and Hydroalkenylation of Alkenyl Carboxylic Acids. Angewandte Chemie (International Ed. in English). PMID 32894810 DOI: 10.1002/Anie.202010840  0.395
2020 Gao Y, Wu ZQ, Engle KM. Synthesis of Stereodefined 1,1-Diborylalkenes via Copper-Catalyzed Diboration of Terminal Alkynes. Organic Letters. PMID 32574499 DOI: 10.1021/Acs.Orglett.0C01901  0.494
2020 Gao DW, Gao Y, Shao H, Qiao TZ, Wang X, Sanchez BB, Chen JS, Liu P, Engle KM. Cascade CuH-Catalysed Conversion of Alkynes to Enantioenriched 1,1-Disubstituted Products. Nature Catalysis. 3: 23-29. PMID 32420528 DOI: 10.1038/s41929-019-0384-6  0.777
2020 Vasquez AM, Gurak JA, Joe C, Cherney EC, Engle KM. Catalytic α-Hydroarylation of Acrylates and Acrylamides via an Interrupted Hydrodehalogenation Reaction. Journal of the American Chemical Society. PMID 32379433 DOI: 10.1021/Jacs.0C03040  0.434
2020 Oxtoby L, Li ZQ, Tran V, Erbay T, Deng R, Liu P, Engle KM. A Transient Directing Group Strategy Enables Enantioselective Reductive Heck Hydroarylation of Alkenes. Angewandte Chemie (International Ed. in English). PMID 32196876 DOI: 10.1002/Anie.202001069  0.501
2020 Tran V, Li ZQ, Apolinar O, Derosa J, Wisniewski S, Joannou MV, Eastgate M, Engle KM. Ni(COD)(DQ): An Air-Stable 18-Electron Ni(0)-Olefin Precatalyst. Angewandte Chemie (International Ed. in English). PMID 32065839 DOI: 10.1002/Anie.202000124  0.658
2020 Tran V, Li ZQ, Gallagher T, Derosa J, Liu P, Engle KM. Integrating Allyl Electrophiles into Nickel-Catalyzed Conjunctive Cross-Coupling. Angewandte Chemie (International Ed. in English). PMID 31958202 DOI: 10.1002/Anie.201915454  0.739
2020 Tran VT, Nimmagadda SK, Liu M, Engle KM. Recent applications of chiral phosphoric acids in palladium catalysis. Organic & Biomolecular Chemistry. PMID 31907504 DOI: 10.1039/C9Ob02205H  0.835
2020 Derosa J, Apolinar O, Kang T, Tran VT, Engle KM. Recent developments in nickel-catalyzed intermolecular dicarbofunctionalization of alkenes Chemical Science. 11: 4287-4296. DOI: 10.1039/C9Sc06006E  0.674
2019 Medina JM, Kang T, Erbay TG, Shao H, Gallego GM, Yang S, Tran-Dubé M, Richardson PF, Derosa J, Helsel RT, Patman RL, Wang F, Ashcroft CP, Braganza JF, McAlpine I, ... ... Engle KM, et al. Cu-Catalyzed Hydroboration of Benzylidenecyclopropanes: Reaction Optimization, (Hetero)Aryl Scope, and Origins of Pathway Selectivity. Acs Catalysis. 9: 11130-11136. PMID 32617185 DOI: 10.1021/Acscatal.9B03557  0.798
2019 Oxtoby LJ, Gurak JA, Wisniewski SR, Eastgate MD, Engle KM. Palladium-Catalyzed Reductive Heck Coupling of Alkenes. Trends in Chemistry. 1: 572-587. PMID 32542234 DOI: 10.1016/j.trechm.2019.05.007  0.385
2019 Romine AM, Yang KS, Karunananda MK, Chen JS, Engle KM. Synthetic and Mechanistic Studies of a Versatile Heteroaryl Thioether Directing Group for Pd(II) Catalysis. Acs Catalysis. 9: 7626-7640. PMID 32542117 DOI: 10.1021/Acscatal.9B01471  0.837
2019 Liu Z, Li X, Zeng T, Engle KM. Directed, Palladium(II)-Catalyzed Enantioselective anti-Carboboration of Alkenyl Carbonyl Compounds. Acs Catalysis. 9: 3260-3265. PMID 31799023 DOI: 10.1021/Acscatal.9B00181  0.626
2019 Jankins TC, Qin Z, Engle KM. A practical method for N-alkylation of phosphinic (thio)amides with alcohols via transfer hydrogenation. Tetrahedron. 75: 3272-3281. PMID 31745374 DOI: 10.1016/J.Tet.2019.04.029  0.352
2019 Derosa J, Kang T, Tran VT, Wisniewski S, Karunananda MK, Jankins TC, Xu KL, Engle KM. Nickel-Catalyzed 1,2-Diarylation of Alkenyl Carboxylates: A Gateway to 1,2,3-Trifunctionalized Building Blocks. Angewandte Chemie (International Ed. in English). PMID 31693286 DOI: 10.1002/Anie.201913062  0.833
2019 Lv H, Kang H, Zhou B, Xue X, Engle KM, Zhao D. Nickel-catalyzed intermolecular oxidative Heck arylation driven by transfer hydrogenation. Nature Communications. 10: 5025. PMID 31690717 DOI: 10.1038/S41467-019-12949-1  0.504
2019 Liu Z, Chen J, Lu HX, Li X, Gao Y, Coombs J, Goldfogel M, Engle KM. Pd(0)-Catalyzed Directed syn-1,2-Carboboration and -Silylation: Alkene Scope, Applications in Dearomatization, and Stereocontrol via a Chiral Auxiliary. Angewandte Chemie (International Ed. in English). PMID 31538388 DOI: 10.1002/Anie.201910304  0.591
2019 Nimmagadda SK, Liu M, Karunananda MK, Gao DW, Apolinar O, Chen JS, Liu P, Engle KM. Catalytic, Enantioselective α-Alkylation of Azlactones with Non-Conjugated Alkenes via Directed Nucleopalladation. Angewandte Chemie (International Ed. in English). PMID 30729619 DOI: 10.1002/Anie.201814272  0.8
2019 Medina JM, Kang T, Erbay TG, Shao H, Gallego GM, Yang S, Tran-Dubé M, Richardson PF, Derosa J, Helsel RT, Patman RL, Wang F, Ashcroft CP, Braganza JF, McAlpine I, ... ... Engle KM, et al. Cu-Catalyzed Hydroboration of Benzylidenecyclopropanes: Reaction Optimization, (Hetero)Aryl Scope, and Origins of Pathway Selectivity Acs Catalysis. 9: 11130-11136. DOI: 10.1021/acscatal.9b03557  0.751
2019 Romine AM, Yang KS, Karunananda MK, Chen JS, Engle KM. Synthetic and Mechanistic Studies of a Versatile Heteroaryl Thioether Directing Group for Pd(II) Catalysis Acs Catalysis. 9: 7626-7640. DOI: 10.1021/ACSCATAL.9B01471  0.796
2019 Liu Z, Gao Y, Zeng T, Engle KM. Transition‐Metal‐Catalyzed 1,2‐Carboboration of Alkenes: Strategies, Mechanisms, and Stereocontrol Israel Journal of Chemistry. 60: 219-229. DOI: 10.1002/Ijch.201900087  0.523
2018 Luo SX, Engle KM, Dong X, Hejl A, Takase MK, Henling LM, Liu P, Houk KN, Grubbs RH. An Initiation Kinetics Prediction Model Enables Rational Design of Ruthenium Olefin Metathesis Catalysts Bearing Modified Chelating Benzylidenes. Acs Catalysis. 8: 4600-4611. PMID 32528741 DOI: 10.1021/Acscatal.8B00843  0.768
2018 O'Duill ML, Engle KM. Protodepalladation as a Strategic Elementary Step in Catalysis. Synthesis. 50: 4699-4714. PMID 31105348 DOI: 10.1055/S-0037-1611064  0.825
2018 Gao DW, Xiao Y, Liu M, Liu Z, Karunananda MK, Chen JS, Engle KM. Catalytic, Enantioselective Synthesis of Allenyl Boronates. Acs Catalysis. 8: 3650-3654. PMID 30740261 DOI: 10.1021/Acscatal.8B00626  0.838
2018 Matsuura R, Jankins TC, Hill DE, Yang KS, Gallego GM, Yang S, He M, Wang F, Marsters RP, McAlpine I, Engle KM. Palladium(ii)-catalyzed γ-selective hydroarylation of alkenyl carbonyl compounds with arylboronic acids. Chemical Science. 9: 8363-8368. PMID 30542583 DOI: 10.1039/C8Sc03081B  0.825
2018 Derosa J, Kleinmans R, Tran VT, Karunananda MK, Wisniewski SR, Eastgate MD, Engle KM. Nickel-Catalyzed 1,2-Diarylation of Simple Alkenyl Amides. Journal of the American Chemical Society. PMID 30525575 DOI: 10.1021/Jacs.8B11942  0.838
2018 Gurak JA, Engle KM. Practical Intermolecular Hydroarylation of Terminal Alkenes via Reductive Heck Coupling. Acs Catalysis. 8: 8987-8992. PMID 30393575 DOI: 10.1021/Acscatal.8B02717  0.515
2018 Tran VT, Gurak JA, Yang KS, Engle KM. Activation of diverse carbon-heteroatom and carbon-carbon bonds via palladium(II)-catalysed β-X elimination. Nature Chemistry. PMID 30127512 DOI: 10.1038/S41557-018-0110-Z  0.824
2018 Derosa J, van der Puyl VA, Tran VT, Liu M, Engle KM. Directed nickel-catalyzed 1,2-dialkylation of alkenyl carbonyl compounds. Chemical Science. 9: 5278-5283. PMID 29997883 DOI: 10.1039/C8Sc01735B  0.715
2018 Gao DW, Vinogradova EV, Nimmagadda SK, Medina JM, Xiao Y, Suciu RM, Cravatt BF, Engle KM. Direct Access to Versatile Electrophiles via Catalytic Oxidative Cyanation of Alkenes. Journal of the American Chemical Society. PMID 29894184 DOI: 10.1021/Jacs.8B03704  0.814
2018 Zeng T, Liu Z, Schmidt MA, Eastgate MD, Engle KM. Directed, Palladium(II)-Catalyzed Intermolecular Aminohydroxylation of Alkenes Using a Mild Oxidation System. Organic Letters. PMID 29888604 DOI: 10.1021/Acs.Orglett.8B01440  0.574
2018 Liu M, Yang P, Karunananda MK, Wang Y, Liu P, Engle KM. C(alkenyl)-H Activation via Six-Membered Palladacycles: Catalytic 1,3-Diene Synthesis. Journal of the American Chemical Society. PMID 29630359 DOI: 10.1021/Jacs.8B02124  0.818
2018 Derosa J, O'Duill ML, Holcomb M, Boulous MN, Patman RL, Wang F, Tran-Dubé M, McAlpine I, Engle KM. Copper-Catalyzed Chan-Lam Cyclopropylation of Phenols and Azaheterocycles. The Journal of Organic Chemistry. PMID 29498847 DOI: 10.1021/Acs.Joc.7B03100  0.813
2018 Liu Z, Ni HQ, Zeng T, Engle KM. Catalytic Carbo- and Aminoboration of Alkenyl Carbonyl Compounds via 5- and 6-Membered Palladacycles. Journal of the American Chemical Society. PMID 29384373 DOI: 10.1021/Jacs.8B00881  0.576
2018 van der Puyl VA, Derosa J, Engle KM. Directed, Nickel-Catalyzed Umpolung 1,2-Carboamination of Alkenyl Carbonyl Compounds Acs Catalysis. 9: 224-229. DOI: 10.1021/Acscatal.8B04516  0.728
2018 Luo S, Engle KM, Dong X, Hejl A, Takase MK, Henling LM, Liu P, Houk KN, Grubbs RH. An Initiation Kinetics Prediction Model Enables Rational Design of Ruthenium Olefin Metathesis Catalysts Bearing Modified Chelating Benzylidenes Acs Catalysis. 8: 4600-4611. DOI: 10.1021/acscatal.8b00843  0.787
2017 O'Duill ML, Matsuura R, Wang Y, Turnbull JL, Gurak JA, Gao DW, Lu G, Liu P, Engle KM. Tridentate Directing Groups Stabilize 6-Membered Palladacycles in Catalytic Alkene Hydrofunctionalization. Journal of the American Chemical Society. PMID 28972751 DOI: 10.1021/Jacs.7B08383  0.811
2017 Derosa J, Tran V, Boulous MN, Chen JS, Engle KM. Nickel-Catalyzed β,γ-Dicarbofunctionalization of Alkenyl Carbonyl Compounds via Conjunctive Cross-Coupling. Journal of the American Chemical Society. PMID 28738150 DOI: 10.1021/Jacs.7B06567  0.722
2017 Liu Z, Wang Y, Wang Z, Zeng T, Liu P, Engle KM. Catalytic Intermolecular Carboamination of Unactivated Alkenes via Directed Aminopalladation. Journal of the American Chemical Society. PMID 28727452 DOI: 10.1021/Jacs.7B06520  0.61
2017 Derosa J, Cantu AL, Boulous MN, O'Duill ML, Turnbull JL, Liu Z, De La Torre DM, Engle KM. Palladium(II)-Catalyzed Directed anti-Hydrochlorination of Unactivated Alkynes with HCl. Journal of the American Chemical Society. PMID 28266849 DOI: 10.1021/Jacs.7B00892  0.832
2017 Engle K, Gurak J. Regioselective Hydroamination Using a Directed Nucleopalladation/Protodepalladation Strategy Synlett. 28: 2057-2065. DOI: 10.1055/S-0036-1589077  0.485
2017 Gurak JA, Tran VT, Sroda MM, Engle KM. N-alkylation of 2-pyridone derivatives via palladium(II)-catalyzed directed alkene hydroamination Tetrahedron. 73: 3636-3642. DOI: 10.1016/J.Tet.2017.03.091  0.543
2016 Liu Z, Zeng T, Yang KS, Engle KM. β,γ-Vicinal Dicarbofunctionalization of Alkenyl Carbonyl Compounds via Directed Nucleopalladation. Journal of the American Chemical Society. PMID 27779861 DOI: 10.1021/Jacs.6B09170  0.832
2016 Yang KS, Gurak JA, Liu Z, Engle KM. Catalytic, Regioselective Hydrocarbofunctionalization of Unactivated Alkenes with Diverse C-H Nucleophiles. Journal of the American Chemical Society. PMID 27709911 DOI: 10.1021/Jacs.6B08850  0.841
2016 Luo SX, Cannon JS, Taylor BL, Engle KM, Houk KN, Grubbs RH. Z-Selective Cross-Metathesis and Homodimerization of 3E-1,3-Dienes: Reaction Optimization, Computational Analysis, and Synthetic Applications. Journal of the American Chemical Society. PMID 27689541 DOI: 10.1021/Jacs.6B08387  0.826
2016 Pfeifer L, Engle KM, Pidgeon GW, Sparkes HA, Thompson AL, Brown JM, Gouverneur VE. Hydrogen-Bonded Homoleptic Fluoride-Diarylurea Complexes: Structure, Reactivity and Coordinating Power. Journal of the American Chemical Society. PMID 27608274 DOI: 10.1021/Jacs.6B07501  0.72
2016 Liu Z, Derosa J, Engle KM. Palladium(II)-Catalyzed Regioselective syn-Hydroarylation of Disubstituted Alkynes Using a Removable Directing Group. Journal of the American Chemical Society. PMID 27602748 DOI: 10.1021/Jacs.6B08818  0.765
2016 Lee J, Grandner JM, Engle KM, Houk KN, Grubbs RH. In Situ Catalyst Modification in Atom Transfer Radical Reactions with Ruthenium Benzylidene Complexes. Journal of the American Chemical Society. 138: 7171-7. PMID 27186790 DOI: 10.1021/Jacs.6B03767  0.62
2016 Yang KS, Engle KM. Organic chemistry: Precision pruning of molecules. Nature. 533: 183-184. PMID 27172040 DOI: 10.1038/533183A  0.824
2016 Gurak JA, Yang KS, Liu Z, Engle KM. Directed, Regiocontrolled Hydroamination of Unactivated Alkenes via Protodepalladation. Journal of the American Chemical Society. PMID 27093112 DOI: 10.1021/Jacs.6B02718  0.843
2016 Engle KM. The mechanism of palladium(II)-mediated C-H cleavage with mono-N-protected amino acid (MPAA) ligands: Origins of rate acceleration Pure and Applied Chemistry. 88: 119-138. DOI: 10.1515/Pac-2015-0902  0.386
2015 Engle KM, Pfeifer L, Pidgeon GW, Giuffredi GT, Thompson AL, Paton RS, Brown JM, Gouverneur V. Coordination diversity in hydrogen-bonded homoleptic fluoride-alcohol complexes modulates reactivity. Chemical Science. 6: 5293-5302. PMID 29449931 DOI: 10.1039/C5Sc01812A  0.682
2015 Engle KM, Dastbaravardeh N, Thuy-Boun PS, Wang DH, Sather AC, Yu JQ. Ligand-Accelerated ortho-C-H Olefination of Phenylacetic Acids. Organic Syntheses; An Annual Publication of Satisfactory Methods For the Preparation of Organic Chemicals. 92: 58-75. PMID 27397943 DOI: 10.15227/Orgsyn.092.0058  0.645
2015 Engle KM, Lu G, Luo SX, Henling LM, Takase MK, Liu P, Houk KN, Grubbs RH. Origins of initiation rate differences in ruthenium olefin metathesis catalysts containing chelating benzylidenes. Journal of the American Chemical Society. 137: 5782-92. PMID 25897653 DOI: 10.1021/Jacs.5B01144  0.797
2015 Koy M, Engle KM, Henling LM, Takase MK, Grubbs RH. Synthesis of substituted dihydrobenzofurans via tandem S(N)Ar/5-exo-trig cyclization. Organic Letters. 17: 1986-9. PMID 25853213 DOI: 10.1021/Acs.Orglett.5B00743  0.578
2015 Engle KM, Luo SX, Grubbs RH. An S(N)Ar approach to sterically hindered ortho-alkoxybenzaldehydes for the synthesis of olefin metathesis catalysts. The Journal of Organic Chemistry. 80: 4213-20. PMID 25826714 DOI: 10.1021/Acs.Joc.5B00563  0.821
2015 Wang XC, Gong W, Fang LZ, Zhu RY, Li S, Engle KM, Yu JQ. Ligand-enabled meta-C-H activation using a transient mediator. Nature. 519: 334-8. PMID 25754328 DOI: 10.1038/nature14214  0.704
2015 Engle KM, Pfeifer L, Pidgeon GW, Giuffredi GT, Thompson AL, Paton RS, Brown JM, Gouverneur V. Coordination diversity in hydrogen-bonded homoleptic fluoride-alcohol complexes modulates reactivity Chemical Science. 6: 5293-5302. DOI: 10.1039/c5sc01812a  0.608
2015 Engle KM, Luo S, Grubbs RH. ChemInform Abstract: An SNAr Approach to Sterically Hindered ortho-Alkoxybenzaldehydes for the Synthesis of Olefin Metathesis Catalysts. Cheminform. 46: no-no. DOI: 10.1002/chin.201535086  0.781
2015 Koy M, Engle KM, Henling LM, Takase MK, Grubbs RH. ChemInform Abstract: Synthesis of Substituted Dihydrobenzofurans via Tandem SNAr/5-exo-trig Cyclization. Cheminform. 46: no-no. DOI: 10.1002/chin.201530147  0.46
2013 Wolstenhulme JR, Rosenqvist J, Lozano O, Ilupeju J, Wurz N, Engle KM, Pidgeon GW, Moore PR, Sandford G, Gouverneur V. Asymmetric electrophilic fluorocyclization with carbon nucleophiles. Angewandte Chemie (International Ed. in English). 52: 9796-800. PMID 23873744 DOI: 10.1002/Anie.201304845  0.651
2013 Wang H, Li G, Engle KM, Yu JQ, Davies HM. Sequential C-H functionalization reactions for the enantioselective synthesis of highly functionalized 2,3-dihydrobenzofurans. Journal of the American Chemical Society. 135: 6774-7. PMID 23600441 DOI: 10.1021/Ja401731D  0.637
2013 Engle KM, Yu JQ. Developing ligands for palladium(II)-catalyzed C-H functionalization: intimate dialogue between ligand and substrate. The Journal of Organic Chemistry. 78: 8927-55. PMID 23565982 DOI: 10.1021/Jo400159Y  0.622
2013 Mizuta S, Engle KM, Verhoog S, Galicia-López O, O'Duill M, Médebielle M, Wheelhouse K, Rassias G, Thompson AL, Gouverneur V. Trifluoromethylation of allylsilanes under photoredox catalysis. Organic Letters. 15: 1250-3. PMID 23465076 DOI: 10.1021/Ol400184T  0.806
2013 Mizuta S, Verhoog S, Engle KM, Khotavivattana T, O'Duill M, Wheelhouse K, Rassias G, Médebielle M, Gouverneur V. Catalytic hydrotrifluoromethylation of unactivated alkenes. Journal of the American Chemical Society. 135: 2505-8. PMID 23373772 DOI: 10.1021/Ja401022X  0.776
2013 Engle KM, Yu J. ChemInform Abstract: Transition Metal Catalyzed C-H Functionalization. Synthetically Enabling Reactions for Building Molecular Complexity Cheminform. 44: no-no. DOI: 10.1002/chin.201325221  0.534
2012 Mei TS, Kou L, Ma S, Engle KM, Yu JQ. Heterocycle Formation via Palladium-Catalyzed C-H Functionalization. Synthesis. 44: 1778-1791. PMID 27397938 DOI: 10.1055/S-0031-1289766  0.736
2012 Mizuta S, Galicia-López O, Engle KM, Verhoog S, Wheelhouse K, Rassias G, Gouverneur V. Trifluoromethylation of allylsilanes under copper catalysis. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 8583-7. PMID 22692972 DOI: 10.1002/Chem.201201707  0.644
2012 Baxter RD, Sale D, Engle KM, Yu JQ, Blackmond DG. Mechanistic rationalization of unusual kinetics in Pd-catalyzed C-H olefination. Journal of the American Chemical Society. 134: 4600-6. PMID 22324814 DOI: 10.1021/Ja207634T  0.655
2012 Engle KM, Mei TS, Wasa M, Yu JQ. Weak coordination as a powerful means for developing broadly useful C-H functionalization reactions. Accounts of Chemical Research. 45: 788-802. PMID 22166158 DOI: 10.1021/Ar200185G  0.804
2012 Mei TS, Kou L, Ma S, Engle K, Yu JQ. Heterocycle formation via palladium-catalyzed C-H functionalization Synthesis (Germany). 44: 1778-1791. DOI: 10.1055/s-0031-1289766  0.67
2012 Engle KM, Yu JQ, Davies HML, Xi Z, You SL, Shi ZJ. Transition Metal-Catalyzed C-H Functionalization: Synthetically Enabling Reactions for Building Molecular Complexity Organic Chemistry - Breakthroughs and Perspectives. 279-333. DOI: 10.1002/9783527664801.ch8  0.488
2011 Wasa M, Engle KM, Lin DW, Yoo EJ, Yu JQ. Pd(II)-catalyzed enantioselective C-H activation of cyclopropanes. Journal of the American Chemical Society. 133: 19598-601. PMID 22059375 DOI: 10.1021/Ja207607S  0.809
2011 Engle KM, Thuy-Boun PS, Dang M, Yu JQ. Ligand-accelerated cross-coupling of C(sp2)-H bonds with arylboron reagents. Journal of the American Chemical Society. 133: 18183-93. PMID 21913636 DOI: 10.1021/Ja203978R  0.62
2011 Engle KM, Mei TS, Wang X, Yu JQ. Bystanding F+ oxidants enable selective reductive elimination from high-valent metal centers in catalysis. Angewandte Chemie (International Ed. in English). 50: 1478-91. PMID 21264991 DOI: 10.1002/Anie.201005142  0.701
2011 Lu Y, Leow D, Wang X, Engle KM, Yu JQ. Hydroxyl-directed C-H carbonylation enabled by mono-N-protected amino acid ligands: An expedient route to 1-isochromanones Chemical Science. 2: 967-971. DOI: 10.1039/C0Sc00633E  0.633
2011 Engle KM, Mei T, Wang X, Yu J. Passive F+-Oxidationsmittel ermöglichen die selektive reduktive Eliminierung hochvalenter Metallzentren in der Katalyse Angewandte Chemie. 123: 1514-1528. DOI: 10.1002/Ange.201005142  0.635
2010 Wasa M, Engle KM, Yu JQ. Cross-coupling of C(sp)-H Bonds with Organometallic Reagents via Pd(II)/Pd(0) Catalysis** Israel Journal of Chemistry. 50: 605-616. PMID 21552359 DOI: 10.1002/Ijch.201000038  0.742
2010 Engle KM, Wang DH, Yu JQ. Ligand-accelerated C-H activation reactions: evidence for a switch of mechanism. Journal of the American Chemical Society. 132: 14137-51. PMID 20853838 DOI: 10.1021/Ja105044S  0.718
2010 Engle KM, Wang DH, Yu JQ. Constructing multiply substituted arenes using sequential palladium(II)-catalyzed C-H olefination. Angewandte Chemie (International Ed. in English). 49: 6169-73. PMID 20632344 DOI: 10.1002/Anie.201002077  0.731
2010 Lu Y, Wang DH, Engle KM, Yu JQ. Pd(II)-catalyzed hydroxyl-directed C-H olefination enabled by monoprotected amino acid ligands. Journal of the American Chemical Society. 132: 5916-21. PMID 20359184 DOI: 10.1021/Ja101909T  0.755
2010 Wasa M, Engle KM, Yu JQ. Pd(II)-catalyzed olefination of sp3 C-H bonds. Journal of the American Chemical Society. 132: 3680-1. PMID 20187642 DOI: 10.1021/Ja1010866  0.753
2010 Wang DH, Engle KM, Shi BF, Yu JQ. Ligand-enabled reactivity and selectivity in a synthetically versatile aryl C-H olefination. Science (New York, N.Y.). 327: 315-9. PMID 19965380 DOI: 10.1126/Science.1182512  0.789
2010 Wasa M, Engle KM, Yu J. Cover Picture: Cross-Coupling of C(sp3)-H Bonds with Organometallic Reagents via Pd(II)/Pd(0) Catalysis (Isr. J. Chem. 5-6/2010) Israel Journal of Chemistry. 50: 537-537. DOI: 10.1002/Ijch.201090011  0.711
2010 Wasa M, Engle KM, Yu JQ. Cross-coupling of C(sp3)-H bonds with organometallic reagents via Pd(II)/Pd(0) catalysis Israel Journal of Chemistry. 50: 605-616. DOI: 10.1002/ijch.201000038  0.688
2009 Giri R, Shi BF, Engle KM, Maugel N, Yu JQ. Transition metal-catalyzed C-H activation reactions: diastereoselectivity and enantioselectivity. Chemical Society Reviews. 38: 3242-72. PMID 19847354 DOI: 10.1039/B816707A  0.756
2009 Wasa M, Engle KM, Yu JQ. Pd(0)/PR3-catalyzed intermolecular arylation of sp3 C-H bonds. Journal of the American Chemical Society. 131: 9886-7. PMID 19580277 DOI: 10.1021/Ja903573P  0.739
2009 Chen X, Engle KM, Wang DH, Yu JQ. Palladium(II)-catalyzed C-H activation/C-C cross-coupling reactions: versatility and practicality. Angewandte Chemie (International Ed. in English). 48: 5094-115. PMID 19557755 DOI: 10.1002/Anie.200806273  0.691
2009 Chen X, Engle K, Wang D, Yu J. Palladium(II)-katalysierte C-H-Aktivierung/C-C-Kreuzkupplung: Vielseitigkeit und Anwendbarkeit Angewandte Chemie. 121: 5196-5217. DOI: 10.1002/Ange.200806273  0.636
2007 Plass KE, Engle KM, Matzger AJ. Contrasting two- and three-dimensional crystal properties of isomeric dialkyl phthalates. Journal of the American Chemical Society. 129: 15211-7. PMID 18001022 DOI: 10.1021/Ja0744798  0.59
2006 Plass KE, Engle KM, Cychosz KA, Matzger AJ. Large-periodicity two-dimensional crystals by cocrystallization. Nano Letters. 6: 1178-83. PMID 16771576 DOI: 10.1021/Nl0605061  0.599
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