Yu-Dong Zhou - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
Synaptic physiology, epilepsy, adult neurogenesis

19/94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Liu C, Yang TQ, Zhou YD, Shen Y. oReduced astrocytic mGluR5 in the hippocampus is associated with stress-induced depressive-like behaviors in mice. Neuroscience Letters. 136766. PMID 35779694 DOI: 10.1016/j.neulet.2022.136766  0.302
2021 Chen J, Ma XL, Zhao H, Wang XY, Xu MX, Wang H, Yang TQ, Peng C, Liu SS, Huang M, Zhou YD, Shen Y. Increasing astrogenesis in the developing hippocampus induces autistic-like behavior in mice via enhancing inhibitory synaptic transmission. Glia. PMID 34498776 DOI: 10.1002/glia.24091  0.377
2020 Ren J, Yan Y, Cheng S, Long J, Zhang H, Wang J, Shen Y, Zhou YD, Anderson MP. . Brain, Behavior, and Immunity. PMID 32827701 DOI: 10.1016/J.Bbi.2020.08.017  0.486
2019 Hao S, Yang H, Wang X, He Y, Xu H, Wu X, Pan L, Liu Y, Lou H, Xu H, Ma H, Xi W, Zhou Y, Duan S, Wang H. The Lateral Hypothalamic and BNST GABAergic Projections to the Anterior Ventrolateral Periaqueductal Gray Regulate Feeding. Cell Reports. 28: 616-624.e5. PMID 31315042 DOI: 10.1016/J.Celrep.2019.06.051  0.333
2019 He Y, Wei M, Wu Y, Qin H, Li W, Ma X, Cheng J, Ren J, Shen Y, Chen Z, Sun B, Huang FD, Shen Y, Zhou YD. Amyloid β oligomers suppress excitatory transmitter release via presynaptic depletion of phosphatidylinositol-4,5-bisphosphate. Nature Communications. 10: 1193. PMID 30867420 DOI: 10.1016/J.Ibror.2019.07.743  0.408
2018 Li Y, Li CY, Xi W, Jin S, Wu ZH, Jiang P, Dong P, He XB, Xu FQ, Duan S, Zhou YD, Li XM. Rostral and Caudal Ventral Tegmental Area GABAergic Inputs to Different Dorsal Raphe Neurons Participate in Opioid Dependence. Neuron. PMID 30638902 DOI: 10.1016/J.Neuron.2018.12.012  0.328
2018 Cheng J, Wang J, Ma X, Ullah R, Shen Y, Zhou YD. Anterior Paraventricular Thalamus to Nucleus Accumbens Projection Is Involved in Feeding Behavior in a Novel Environment. Frontiers in Molecular Neuroscience. 11: 202. PMID 29930498 DOI: 10.3389/Fnmol.2018.00202  0.467
2018 Wang Y, Liang J, Chen L, Shen Y, Zhao J, Xu C, Wu X, Cheng H, Ying X, Guo Y, Wang S, Zhou Y, Wang Y, Chen Z. Pharmaco-genetic therapeutics targeting parvalbumin neurons attenuate temporal lobe epilepsy. Neurobiology of Disease. PMID 29894753 DOI: 10.1016/J.Nbd.2018.06.006  0.32
2018 Chen J, He Y, Wu Y, Zhou H, Su LD, Li WN, Olsen RW, Liang J, Zhou YD, Shen Y. Single Ethanol Withdrawal Regulates Extrasynaptic δ-GABA Receptors Via PKCδ Activation. Frontiers in Molecular Neuroscience. 11: 141. PMID 29755316 DOI: 10.3389/Fnmol.2018.00141  0.359
2016 Shen Y, Qin H, Chen J, Mou L, He Y, Yan Y, Zhou H, Lv Y, Chen Z, Wang J, Zhou YD. Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons. The Journal of Cell Biology. 215: 719-734. PMID 27920126 DOI: 10.1083/Jcb.201605046  0.368
2016 Li C, Yan Y, Cheng J, Xiao G, Gu J, Zhang L, Yuan S, Wang J, Shen Y, Zhou YD. Toll-Like Receptor 4 Deficiency Causes Reduced Exploratory Behavior in Mice Under Approach-Avoidance Conflict. Neuroscience Bulletin. PMID 26898297 DOI: 10.1007/S12264-016-0015-Z  0.487
2012 Zhou YD, Zhang D, Ozkaynak E, Wang X, Kasper EM, Leguern E, Baulac S, Anderson MP. Epilepsy gene LGI1 regulates postnatal developmental remodeling of retinogeniculate synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 903-10. PMID 22262888 DOI: 10.1523/Jneurosci.5191-11.2012  0.543
2011 Czupryn A, Zhou YD, Chen X, McNay D, Anderson MP, Flier JS, Macklis JD. Transplanted hypothalamic neurons restore leptin signaling and ameliorate obesity in db/db mice. Science (New York, N.Y.). 334: 1133-7. PMID 22116886 DOI: 10.1126/Science.1209870  0.524
2011 Smith SE, Zhou YD, Zhang G, Jin Z, Stoppel DC, Anderson MP. Increased gene dosage of Ube3a results in autism traits and decreased glutamate synaptic transmission in mice. Science Translational Medicine. 3: 103ra97. PMID 21974935 DOI: 10.1126/Scitranslmed.3002627  0.624
2009 Zhou YD, Lee S, Jin Z, Wright M, Smith SE, Anderson MP. Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy. Nature Medicine. 15: 1208-14. PMID 19701204 DOI: 10.1038/Nm.2019  0.619
2008 Keck T, Lillis KP, Zhou YD, White JA. Frequency-dependent glycinergic inhibition modulates plasticity in hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7359-69. PMID 18632940 DOI: 10.1523/JNEUROSCI.5618-07.2008  0.691
2005 Zhou YD, Acker CD, Netoff TI, Sen K, White JA. Increasing Ca2+ transients by broadening postsynaptic action potentials enhances timing-dependent synaptic depression. Proceedings of the National Academy of Sciences of the United States of America. 102: 19121-5. PMID 16365307 DOI: 10.1073/pnas.0509856103  0.66
2003 Zhou YD, Turner TJ, Dunlap K. Enhanced G protein-dependent modulation of excitatory synaptic transmission in the cerebellum of the Ca2+ channel-mutant mouse, tottering. The Journal of Physiology. 547: 497-507. PMID 12562906 DOI: 10.1113/jphysiol.2002.033415  0.578
2000 Tsen G, Williams B, Allaire P, Zhou YD, Ikonomov O, Kondova I, Jacob MH. Receptors with opposing functions are in postsynaptic microdomains under one presynaptic terminal. Nature Neuroscience. 3: 126-32. PMID 10649567 DOI: 10.1038/72066  0.432
Low-probability matches (unlikely to be authored by this person)
2020 Chen B, Xu C, Wang Y, Lin W, Wang Y, Chen L, Cheng H, Xu L, Hu T, Zhao J, Dong P, Guo Y, Zhang S, Wang S, Zhou Y, et al. A disinhibitory nigra-parafascicular pathway amplifies seizure in temporal lobe epilepsy. Nature Communications. 11: 923. PMID 32066723 DOI: 10.1038/S41467-020-14648-8  0.299
2019 Wang Y, Wang Y, Xu C, Wang S, Tan N, Chen C, Chen L, Wu X, Fei F, Cheng H, Lin W, Qi Y, Chen B, Liang J, Zhao J, ... ... Zhou Y, et al. Direct Septum-Hippocampal Cholinergic Circuit Attenuates Seizure Through Driving Somatostatin Inhibition. Biological Psychiatry. PMID 31987494 DOI: 10.1016/J.Biopsych.2019.11.014  0.294
2016 Ullah R, Shen Y, Zhou YD, Huang K, Fu JF, Wahab F, Shahab M. Expression and actions of GnIH and its orthologs in vertebrates: Current status and advanced knowledge. Neuropeptides. PMID 27255391 DOI: 10.1016/J.Npep.2016.05.004  0.278
2017 Hu TT, Wang RR, Tang YY, Wu YX, Yu J, Hou WW, Lou GD, Zhou YD, Zhang SH, Chen Z. TLR4 deficiency abrogated widespread tactile allodynia, but not widespread thermal hyperalgesia and trigeminal neuropathic pain following partial infraorbital nerve transection. Pain. PMID 29112008 DOI: 10.1097/J.Pain.0000000000001100  0.265
2018 Zhou YD. Glial Regulation of Energy Metabolism. Advances in Experimental Medicine and Biology. 1090: 105-121. PMID 30390287 DOI: 10.1007/978-981-13-1286-1_6  0.264
2015 Liao RJ, Jiang L, Wang RR, Zhao HW, Chen Y, Li Y, Wang L, Jie LY, Zhou YD, Zhang XN, Chen Z, Hu WW. Histidine provides long-term neuroprotection after cerebral ischemia through promoting astrocyte migration. Scientific Reports. 5: 15356. PMID 26481857 DOI: 10.1038/Srep15356  0.261
2016 Feng B, Tang Y, Chen B, Xu C, Wang Y, Dai Y, Wu D, Zhu J, Wang S, Zhou Y, Shi L, Hu W, Zhang X, Chen Z. Transient increase of interleukin-1β after prolonged febrile seizures promotes adult epileptogenesis through long-lasting upregulating endocannabinoid signaling. Scientific Reports. 6: 21931. PMID 26902320 DOI: 10.1038/Srep21931  0.25
2019 Ullah R, Raza A, Rauf N, Shen Y, Zhou YD, Fu J. Postnatal Feeding With a Fat Rich Diet Induces Precocious Puberty Independent of Body Weight, Body Fat, and Leptin Levels in Female Mice. Frontiers in Endocrinology. 10: 758. PMID 31781033 DOI: 10.3389/Fendo.2019.00758  0.243
2017 Ullah R, Su Y, Shen Y, Li C, Xu X, Zhang J, Huang K, Rauf N, He Y, Cheng J, Qin H, Zhou YD, Fu J. Postnatal feeding with high-fat diet induces obesity and precocious puberty in C57BL/6J mouse pups: a novel model of obesity and puberty. Frontiers of Medicine. PMID 28500430 DOI: 10.1007/S11684-017-0530-Y  0.235
2016 Zhou Y, Zhang J, Wang L, Chen Y, Wan Y, He Y, Jiang L, Ma J, Liao R, Zhang X, Shi L, Qin Z, Zhou Y, Chen Z, Hu W. Interleukin-1β impedes oligodendrocyte progenitor cell recruitment and white matter repair following chronic cerebral hypoperfusion. Brain, Behavior, and Immunity. PMID 27663285 DOI: 10.1016/J.Bbi.2016.09.024  0.216
2019 Zhou Y, Zhang J, Wang L, Chen Y, Wan Y, He Y, Jiang L, Ma J, Liao R, Zhang X, Shi L, Qin Z, Zhou Y, Chen Z, Hu W. Corrigendum to 'Interleukin-1β impedes oligodendrocyte progenitor cell recruitment and white matter repair following chronic cerebral hypoperfusion' [Brain Behav. Immun. 60 (2017) 93-105]. Brain, Behavior, and Immunity. PMID 30922729 DOI: 10.1016/J.Bbi.2019.03.020  0.203
2019 Ullah R, Rauf N, Nabi G, Ullah H, Shen Y, Zhou YD, Fu J. Role of Nutrition in the Pathogenesis and Prevention of Non-alcoholic Fatty Liver Disease: Recent Updates. International Journal of Biological Sciences. 15: 265-276. PMID 30745819 DOI: 10.7150/Ijbs.30121  0.193
2020 Wang YJ, Liu MG, Wang JH, Cao W, Wu C, Wang ZY, Liu L, Yang F, Feng ZH, Sun L, Zhang F, Shen Y, Zhou YD, Zhuo M, Luo JH, et al. Restoration of Cingulate Long-Term Depression by Enhancing Non-apoptotic Caspase 3 Alleviates Peripheral Pain Hypersensitivity. Cell Reports. 33: 108369. PMID 33176141 DOI: 10.1016/j.celrep.2020.108369  0.165
2023 Ullah R, Shen Y, Zhou YD, Fu J. Perinatal metabolic inflammation in the hypothalamus impairs the development of homeostatic feeding circuitry. Metabolism: Clinical and Experimental. 147: 155677. PMID 37543245 DOI: 10.1016/j.metabol.2023.155677  0.161
2022 Cheng J, Ma X, Li C, Ullah R, Wang X, Long J, Yuan Z, Liu S, Fu J, Chen Z, Shen Y, Zhou YD. Diet-induced inflammation in the anterior paraventricular thalamus induces compulsive sucrose-seeking. Nature Neuroscience. 25: 1009-1013. PMID 35915173 DOI: 10.1038/s41593-022-01129-y  0.154
2021 Li Y, Li CY, Xi W, Jin S, Wu ZH, Jiang P, Dong P, He XB, Xu FQ, Duan S, Zhou YD, Li XM. Rostral and Caudal Ventral Tegmental Area GABAergic Inputs to Different Dorsal Raphe Neurons Participate in Opioid Dependence. Neuron. 109: 3893-3894. PMID 34856132 DOI: 10.1016/j.neuron.2021.10.038  0.142
2015 Morgan JB, Liu Y, Coothankandaswamy V, Mahdi F, Jekabsons MB, Gerwick WH, Valeriote FA, Zhou YD, Nagle DG. Kalkitoxin inhibits angiogenesis, disrupts cellular hypoxic signaling, and blocks mitochondrial electron transport in tumor cells. Marine Drugs. 13: 1552-68. PMID 25803180 DOI: 10.3390/Md13031552  0.14
2011 Li J, Mahdi F, Du L, Datta S, Nagle DG, Zhou YD. Mitochondrial respiration inhibitors suppress protein translation and hypoxic signaling via the hyperphosphorylation and inactivation of translation initiation factor eIF2α and elongation factor eEF2. Journal of Natural Products. 74: 1894-901. PMID 21875114 DOI: 10.1021/np200370z  0.135
2015 Mahdi F, Morgan JB, Liu W, Agarwal AK, Jekabsons MB, Liu Y, Zhou YD, Nagle DG. Sampangine (a Copyrine Alkaloid) Exerts Biological Activities through Cellular Redox Cycling of Its Quinone and Semiquinone Intermediates. Journal of Natural Products. PMID 26637046 DOI: 10.1021/acs.jnatprod.5b00819  0.134
2018 Lv C, Zeng HW, Wang JX, Yuan X, Zhang C, Fang T, Yang PM, Wu T, Zhou YD, Nagle DG, Zhang WD. The antitumor natural product tanshinone IIA inhibits protein kinase C and acts synergistically with 17-AAG. Cell Death & Disease. 9: 165. PMID 29416003 DOI: 10.1038/s41419-017-0247-5  0.131
2006 Mora FD, Jones DK, Desai PV, Patny A, Avery MA, Feller DR, Smillie T, Zhou YD, Nagle DG. Bioassay for the identification of natural product-based activators of peroxisome proliferator-activated receptor-gamma (PPARgamma): the marine sponge metabolite psammaplin A activates PPARgamma and induces apoptosis in human breast tumor cells. Journal of Natural Products. 69: 547-52. PMID 16643023 DOI: 10.1021/Np050397Q  0.13
2023 Liu D, Wang T, Zhao X, Chen J, Yang T, Shen Y, Zhou YD. Saturated fatty acids stimulate cytokine production in tanycytes via the PP2Ac-dependent signaling pathway. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X231219115. PMID 38069840 DOI: 10.1177/0271678X231219115  0.128
2011 Du L, Mahdi F, Jekabsons MB, Nagle DG, Zhou YD. Natural and semisynthetic mammea-type isoprenylated dihydroxycoumarins uncouple cellular respiration. Journal of Natural Products. 74: 240-8. PMID 21214226 DOI: 10.1021/np100762s  0.125
2011 Mahdi F, Falkenberg M, Ioannou E, Roussis V, Zhou YD, Nagle DG. Thyrsiferol Inhibits Mitochondrial Respiration and HIF-1 Activation. Phytochemistry Letters. 4: 75-78. PMID 21785662 DOI: 10.1016/j.phytol.2010.09.003  0.121
2014 Fan LL, Hu ZH, Zhou YD, Li QQ, Jia YR, Wang JF, Zhao CW. [Intraventricular injection of 5,7-dihydroxytryptamine alters neuronal activity of neurons in the medial prefrontal cortex of rat]. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 66: 667-74. PMID 25516515  0.118
2010 Coothankandaswamy V, Liu Y, Mao SC, Morgan JB, Mahdi F, Jekabsons MB, Nagle DG, Zhou YD. The alternative medicine pawpaw and its acetogenin constituents suppress tumor angiogenesis via the HIF-1/VEGF pathway. Journal of Natural Products. 73: 956-61. PMID 20423107 DOI: 10.1021/np100228d  0.113
2013 Du L, Zhou YD, Nagle DG. Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1. Journal of Natural Products. 76: 1175-81. PMID 23731014 DOI: 10.1021/np400320r  0.111
2024 Wu Y, Lin JY, Zhou YD, Liu HJ, Lu SX, Zhang XK, Guan YY, Nagle DG, Zhang WD, Chen HZ, Luan X. Oncolytic Peptide-Nanoplatform Drives Oncoimmune Response and Reverses Adenosine-Induced Immunosuppressive Tumor Microenvironment. Advanced Healthcare Materials. e2303445. PMID 38290499 DOI: 10.1002/adhm.202303445  0.111
2009 Mao SC, Liu Y, Morgan JB, Jekabsons MB, Zhou YD, Nagle DG. Lipophilic 2,5-disubstituted pyrroles from the marine sponge Mycale sp. inhibit mitochondrial respiration and HIF-1 activation. Journal of Natural Products. 72: 1927-36. PMID 19845338 DOI: 10.1021/np900444m  0.107
2004 Zhou YD, Kim YP, Li XC, Baerson SR, Agarwal AK, Hodges TW, Ferreira D, Nagle DG. Hypoxia-inducible factor-1 activation by (-)-epicatechin gallate: potential adverse effects of cancer chemoprevention with high-dose green tea extracts. Journal of Natural Products. 67: 2063-9. PMID 15620252 DOI: 10.1021/Np040140C  0.106
2013 Li J, Du L, Kelly M, Zhou YD, Nagle DG. Structures and potential antitumor activity of sesterterpenes from the marine sponge Hyrtios communis. Journal of Natural Products. 76: 1492-7. PMID 23944963 DOI: 10.1021/np400350k  0.105
2014 Datta S, Mahdi F, Ali Z, Jekabsons MB, Khan IA, Nagle DG, Zhou YD. Toxins in botanical dietary supplements: blue cohosh components disrupt cellular respiration and mitochondrial membrane potential. Journal of Natural Products. 77: 111-7. PMID 24328138 DOI: 10.1021/Np400758T  0.104
2006 Nagle DG, Zhou YD. Natural product-derived small molecule activators of hypoxia-inducible factor-1 (HIF-1). Current Pharmaceutical Design. 12: 2673-88. PMID 16842166 DOI: 10.2174/138161206777698783  0.102
2008 Liu Y, Liu R, Mao SC, Morgan JB, Jekabsons MB, Zhou YD, Nagle DG. Molecular-targeted antitumor agents. 19. Furospongolide from a marine Lendenfeldia sp. sponge inhibits hypoxia-inducible factor-1 activation in breast tumor cells. Journal of Natural Products. 71: 1854-60. PMID 18989978 DOI: 10.1021/np800342s  0.101
2005 Hossain CF, Kim YP, Baerson SR, Zhang L, Bruick RK, Mohammed KA, Agarwal AK, Nagle DG, Zhou YD. Saururus cernuus lignans--potent small molecule inhibitors of hypoxia-inducible factor-1. Biochemical and Biophysical Research Communications. 333: 1026-33. PMID 15967416 DOI: 10.1016/j.bbrc.2005.05.191  0.1
2012 Du L, Mahdi F, Datta S, Jekabsons MB, Zhou YD, Nagle DG. Structures and mechanisms of antitumor agents: xestoquinones uncouple cellular respiration and disrupt HIF signaling in human breast tumor cells. Journal of Natural Products. 75: 1553-9. PMID 22938093 DOI: 10.1021/np3002892  0.1
2021 Zhai X, Li LS, Zhou YD, Ji WY, Chen H, Xiao H, Liang P. EZH2 regulates the malignancy of human glioblastoma cells via modulation of Twist mRNA stability. European Journal of Pharmacology. 174177. PMID 34015321 DOI: 10.1016/j.ejphar.2021.174177  0.1
2009 Liu Y, Morgan JB, Coothankandaswamy V, Liu R, Jekabsons MB, Mahdi F, Nagle DG, Zhou YD. The Caulerpa pigment caulerpin inhibits HIF-1 activation and mitochondrial respiration. Journal of Natural Products. 72: 2104-9. PMID 19921787 DOI: 10.1021/np9005794  0.1
2000 Bibevski S, Zhou Y, McIntosh JM, Zigmond RE, Dunlap ME. Functional nicotinic acetylcholine receptors that mediate ganglionic transmission in cardiac parasympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5076-82. PMID 10864965 DOI: 10.1523/Jneurosci.20-13-05076.2000  0.099
2004 Mohammed KA, Hossain CF, Zhang L, Bruick RK, Zhou YD, Nagle DG. Laurenditerpenol, a new diterpene from the tropical marine alga Laurenciaintricata that potently inhibits HIF-1 mediated hypoxic signaling in breast tumor cells. Journal of Natural Products. 67: 2002-7. PMID 15620241 DOI: 10.1021/np049753f  0.098
2005 Zhou YD, Kim YP, Mohammed KA, Jones DK, Muhammad I, Dunbar DC, Nagle DG. Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells. Journal of Natural Products. 68: 947-50. PMID 15974627 DOI: 10.1021/np050029m  0.097
2007 Dai J, Liu Y, Jia H, Zhou YD, Nagle DG. Benzochromenones from the marine crinoid Comantheria rotula inhibit hypoxia-inducible factor-1 (HIF-1) in cell-based reporter assays and differentially suppress the growth of certain tumor cell lines. Journal of Natural Products. 70: 1462-6. PMID 17844994 DOI: 10.1021/np070224w  0.096
2007 Liu R, Liu Y, Zhou YD, Nagle DG. Molecular-targeted antitumor agents. 15. Neolamellarins from the marine sponge Dendrilla nigra inhibit hypoxia-inducible factor-1 activation and secreted vascular endothelial growth factor production in breast tumor cells. Journal of Natural Products. 70: 1741-5. PMID 17958397 DOI: 10.1021/np070206e  0.095
2009 Nagle DG, Zhou YD. Marine Natural Products as Inhibitors of Hypoxic Signaling in Tumors. Phytochemistry Reviews : Proceedings of the Phytochemical Society of Europe. 8: 415-429. PMID 20622986 DOI: 10.1007/s11101-009-9120-1  0.095
2006 Nagle DG, Zhou YD. Natural product-based inhibitors of hypoxia-inducible factor-1 (HIF-1). Current Drug Targets. 7: 355-69. PMID 16515532 DOI: 10.2174/138945006776054979  0.094
2013 Li J, Mahdi F, Du L, Jekabsons MB, Zhou YD, Nagle DG. Semisynthetic studies identify mitochondria poisons from botanical dietary supplements--geranyloxycoumarins from Aegle marmelos. Bioorganic & Medicinal Chemistry. 21: 1795-803. PMID 23434131 DOI: 10.1016/j.bmc.2013.01.048  0.093
2010 Du L, Mahdi F, Jekabsons MB, Nagle DG, Zhou YD. Mammea E/BB, an isoprenylated dihydroxycoumarin protonophore that potently uncouples mitochondrial electron transport, disrupts hypoxic signaling in tumor cells. Journal of Natural Products. 73: 1868-72. PMID 20929261 DOI: 10.1021/np100501n  0.092
2006 Dai J, Fishback JA, Zhou YD, Nagle DG. Sodwanone and yardenone triterpenes from a South African species of the marine sponge Axinella inhibit hypoxia-inducible factor-1 (HIF-1) activation in both breast and prostate tumor cells. Journal of Natural Products. 69: 1715-20. PMID 17190448 DOI: 10.1021/np060278q  0.092
2022 Jin J, Wu Y, Zhao Z, Wu Y, Zhou YD, Liu S, Sun Q, Yang G, Lin J, Nagle DG, Qin J, Zhang Z, Chen HZ, Zhang W, Sun S, et al. Small-molecule PROTAC mediates targeted protein degradation to treat STAT3-dependent epithelial cancer. Jci Insight. 7. PMID 36509291 DOI: 10.1172/jci.insight.160606  0.09
2015 Ma J, Zhang J, Hou WW, Wu XH, Liao RJ, Chen Y, Wang Z, Zhang XN, Zhang LS, Zhou YD, Chen Z, Hu WW. Early treatment of minocycline alleviates white matter and cognitive impairments after chronic cerebral hypoperfusion. Scientific Reports. 5: 12079. PMID 26174710 DOI: 10.1038/srep12079  0.09
2010 Morgan JB, Mahdi F, Liu Y, Coothankandaswamy V, Jekabsons MB, Johnson TA, Sashidhara KV, Crews P, Nagle DG, Zhou YD. The marine sponge metabolite mycothiazole: a novel prototype mitochondrial complex I inhibitor. Bioorganic & Medicinal Chemistry. 18: 5988-94. PMID 20637638 DOI: 10.1016/J.Bmc.2010.06.072  0.09
2019 Yuan Z, Ma X, Zhou Y. Anterior paraventricular thalamus to ventromedial nucleus of the hypothalamus projection modulates compulsive sucrose seeking induced by high-fat diet Ibro Reports. 6: S324. DOI: 10.1016/j.ibror.2019.07.1002  0.088
2009 Liu Y, Veena CK, Morgan JB, Mohammed KA, Jekabsons MB, Nagle DG, Zhou YD. Methylalpinumisoflavone inhibits hypoxia-inducible factor-1 (HIF-1) activation by simultaneously targeting multiple pathways. The Journal of Biological Chemistry. 284: 5859-68. PMID 19091749 DOI: 10.1074/jbc.M806744200  0.088
2004 Hodges TW, Hossain CF, Kim YP, Zhou YD, Nagle DG. Molecular-targeted antitumor agents: the Saururus cernuus dineolignans manassantin B and 4-O-demethylmanassantin B are potent inhibitors of hypoxia-activated HIF-1. Journal of Natural Products. 67: 767-71. PMID 15165135 DOI: 10.1021/np030514m  0.087
2023 Zhou F, Cui YX, Zhou YD, Duan ST, Wang ZY, Xia ZH, Hu HY, Liu RQ, Li CW. Baseline pydiflumetofen sensitivity of Fusarium pseudograminearum isolates collected from Henan, China, and potential resistance mechanisms. Plant Disease. PMID 36691280 DOI: 10.1094/PDIS-08-22-1852-RE  0.082
2007 Dai J, Liu Y, Zhou YD, Nagle DG. Cytotoxic metabolites from an Indonesian sponge Lendenfeldia sp. Journal of Natural Products. 70: 1824-6. PMID 17958396 DOI: 10.1021/np070337f  0.082
2020 Fang T, Jiang YX, Chen L, Huang L, Tian XH, Zhou YD, Nagle DG, Zhang DD. Coix Seed Oil Exerts an Anti-Triple-Negative Breast Cancer Effect by Disrupting miR-205/S1PR1 Axis. Frontiers in Pharmacology. 11: 529962. PMID 33101013 DOI: 10.3389/fphar.2020.529962  0.081
2012 Datta S, Li J, Mahdi F, Jekabsons MB, Nagle DG, Zhou YD. Glycolysis inhibitor screening identifies the bis-geranylacylphloroglucinol protonophore moronone from Moronobea coccinea. Journal of Natural Products. 75: 2216-22. PMID 23245650 DOI: 10.1021/np300711e  0.079
2022 Zhou F, Cui YX, Wang BL, Zhou YD, Li SW, Zhang YT, Zhang K, Chen ZY, Hu HY, Li CW. Baseline sensitivity and potential resistance mechanisms for Fusarium pseudograminearum to fludioxonil. Plant Disease. PMID 35100030 DOI: 10.1094/PDIS-12-21-2626-RE  0.077
2013 Datta S, Zhou YD, Nagle DG. Comparative study of chromatographic medium-associated mass and potential antitumor activity loss with bioactive extracts. Journal of Natural Products. 76: 642-7. PMID 23441686 DOI: 10.1021/np300858c  0.075
2008 Sayed KA, Khanfar MA, Shallal HM, Muralidharan A, Awate B, Youssef DT, Liu Y, Zhou YD, Nagle DG, Shah G. Latrunculin A and its C-17-O-carbamates inhibit prostate tumor cell invasion and HIF-1 activation in breast tumor cells. Journal of Natural Products. 71: 396-402. PMID 18298079 DOI: 10.1021/Np070587W  0.074
2004 Nagle DG, Zhou YD, Mora FD, Mohammed KA, Kim YP. Mechanism targeted discovery of antitumor marine natural products. Current Medicinal Chemistry. 11: 1725-56. PMID 15279579  0.073
2010 Mukherjee P, Desai P, Zhou YD, Avery M. Targeting the BH3 domain mediated protein-protein interaction of Bcl-xL through virtual screening. Journal of Chemical Information and Modeling. 50: 906-23. PMID 20392095 DOI: 10.1021/Ci1000373  0.072
2007 Dai J, Liu Y, Zhou YD, Nagle DG. Hypoxia-selective antitumor agents: norsesterterpene peroxides from the marine sponge Diacarnus levii preferentially suppress the growth of tumor cells under hypoxic conditions. Journal of Natural Products. 70: 130-3. PMID 17253866 DOI: 10.1021/np0604883  0.072
2023 Chen JJ, Jin JM, Gu WJ, Zhao Z, Yuan H, Zhou YD, Nagle DG, Xi QL, Zhang XM, Sun QY, Wu Y, Zhang WD, Luan X. Crizotinib-based PROTAC suppresses gastric cancer via promoting MET degradation. Cancer Science. PMID 36692137 DOI: 10.1111/cas.15733  0.07
2006 Nagle DG, Ferreira D, Zhou YD. Epigallocatechin-3-gallate (EGCG): chemical and biomedical perspectives. Phytochemistry. 67: 1849-55. PMID 16876833 DOI: 10.1016/j.phytochem.2006.06.020  0.07
2018 Zhou YD, Li J, Du L, Mahdi F, Le TP, Chen WL, Swanson SM, Watabe K, Nagle DG. Biochemical and Anti-Triple Negative Metastatic Breast Tumor Cell Properties of Psammaplins. Marine Drugs. 16. PMID 30423844 DOI: 10.3390/Md16110442  0.069
2023 Jekabsons MB, Merrell M, Skubiz AG, Thornton N, Milasta S, Green D, Chen T, Wang YH, Avula B, Khan IA, Zhou YD. Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 cells. Cancer & Metabolism. 11: 4. PMID 36805760 DOI: 10.1186/s40170-023-00303-5  0.065
2020 Shen YW, Zhou YD, Luan X, Zhang WD. Blocking CTGF-Mediated Tumor-Stroma Interplay in Pancreatic Cancer. Trends in Molecular Medicine. PMID 32928643 DOI: 10.1016/j.molmed.2020.08.005  0.064
2020 Shen YW, Zhou YD, Chen HZ, Luan X, Zhang WD. Targeting CTGF in Cancer: An Emerging Therapeutic Opportunity. Trends in Cancer. PMID 33358571 DOI: 10.1016/j.trecan.2020.12.001  0.062
2021 Zhang HW, Lv C, Zhang LJ, Guo X, Shen YW, Nagle DG, Zhou YD, Liu SH, Zhang WD, Luan X. Application of omics- and multi-omics-based techniques for natural product target discovery. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 141: 111833. PMID 34175822 DOI: 10.1016/j.biopha.2021.111833  0.057
2022 Bian HT, Shen YW, Zhou YD, Nagle DG, Guan YY, Zhang WD, Luan X. CD47: Beyond an immune checkpoint in cancer treatment. Biochimica Et Biophysica Acta. Reviews On Cancer. 1877: 188771. PMID 35931392 DOI: 10.1016/j.bbcan.2022.188771  0.052
2007 Chittiboyina AG, Kumar GM, Carvalho PB, Liu Y, Zhou YD, Nagle DG, Avery MA. Total synthesis and absolute configuration of laurenditerpenol: a hypoxia inducible factor-1 activation inhibitor. Journal of Medicinal Chemistry. 50: 6299-302. PMID 18004798 DOI: 10.1021/Jm7011062  0.052
2020 Luan X, Wu Y, Shen YW, Zhang H, Zhou YD, Chen HZ, Nagle DG, Zhang WD. Cytotoxic and antitumor peptides as novel chemotherapeutics. Natural Product Reports. PMID 32776055 DOI: 10.1039/d0np00019a  0.041
2023 Lin JY, Liu HJ, Wu Y, Jin JM, Zhou YD, Zhang H, Nagle DG, Chen HZ, Zhang WD, Luan X. Targeted Protein Degradation Technology and Nanomedicine: Powerful Allies against Cancer. Small (Weinheim An Der Bergstrasse, Germany). e2207778. PMID 36693784 DOI: 10.1002/smll.202207778  0.036
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