| Year |
Citation |
Score |
| 2021 |
Johns BE, Ficken M, Engberg ME, Wecker L, Philpot RM. Increasing dietary choline attenuates spatial memory deficits resulting from exposure to the chemotherapeutic agents cyclophosphamide and doxorubicin. Journal of Psychopharmacology (Oxford, England). 2698811211029752. PMID 34225528 DOI: 10.1177/02698811211029752 |
0.55 |
|
| 2019 |
Philpot RM, Ficken M, Johns BE, Engberg ME, Wecker L. Spatial memory deficits in mice induced by chemotherapeutic agents are prevented by acetylcholinesterase inhibitors. Cancer Chemotherapy and Pharmacology. PMID 31302713 DOI: 10.1007/S00280-019-03881-8 |
0.568 |
|
| 2017 |
Wecker L, Marrero-Rosado B, Engberg ME, Johns BE, Philpot RM. 3-Acetylpyridine neurotoxicity in mice. Neurotoxicology. 58: 143-152. PMID 27986589 DOI: 10.1016/J.Neuro.2016.11.010 |
0.609 |
|
| 2016 |
Philpot RM, Ficken M, Wecker L. Doxorubicin and cyclophosphamide lead to long-lasting impairment of spatial memory in female, but not male mice. Behavioural Brain Research. 307: 165-175. PMID 27083301 DOI: 10.1016/J.Bbr.2016.04.017 |
0.591 |
|
| 2016 |
Schroeder RA, Wecker L, Philpot RM. Obstacles and opportunities for cholinergic drug development in the treatment of cognitive disorders. Current Pharmaceutical Design. PMID 26818870 DOI: 10.2174/1381612822666160127111453 |
0.567 |
|
| 2016 |
Schroeder RA, Wecker L, Philpot RM. Obstacles and opportunities for cholinergic drug development in the treatment of cognitive disorders Current Pharmaceutical Design. 22: 1981-1985. DOI: 10.2174/1381612822666160127111453 |
0.528 |
|
| 2015 |
Lambert CS, Philpot RM, Engberg ME, Johns BE, Wecker L. Analysis of gait in rats with olivocerebellar lesions and ability of the nicotinic acetylcholine receptor agonist varenicline to attenuate impairments. Behavioural Brain Research. 291: 342-50. PMID 26049061 DOI: 10.1016/J.Bbr.2015.05.056 |
0.612 |
|
| 2015 |
Philpot RM. Potential Use of Nicotinic Receptor Agonists for the Treatment of Chemotherapy-Induced Cognitive Deficits. Neurochemical Research. PMID 25652578 DOI: 10.1007/S11064-015-1528-Y |
0.338 |
|
| 2015 |
Lambert CS, Philpot RM, Engberg ME, Johns BE, Wecker L. Analysis of gait in rats with olivocerebellar lesions and ability of the nicotinic acetylcholine receptor agonist varenicline to attenuate impairments Behavioural Brain Research. 291: 342-350. DOI: 10.1016/j.bbr.2015.05.056 |
0.567 |
|
| 2014 |
Lambert CS, Philpot RM, Engberg ME, Johns BE, Kim SH, Wecker L. Gait analysis and the cumulative gait index (CGI): Translational tools to assess impairments exhibited by rats with olivocerebellar ataxia. Behavioural Brain Research. 274: 334-43. PMID 25116252 DOI: 10.1016/J.Bbr.2014.08.004 |
0.605 |
|
| 2014 |
Fernandez JW, Grizzell JA, Philpot RM, Wecker L. Postpartum depression in rats: differences in swim test immobility, sucrose preference and nurturing behaviors. Behavioural Brain Research. 272: 75-82. PMID 24983658 DOI: 10.1016/J.Bbr.2014.06.041 |
0.736 |
|
| 2014 |
Philpot RM, Engberg ME, Wecker L. Ethanol conditioned place preference and alterations in ΔFosB following adolescent nicotine administration differ in rats exhibiting high or low behavioral reactivity to a novel environment. Behavioural Brain Research. 262: 101-8. PMID 24412683 DOI: 10.1016/J.Bbr.2013.12.014 |
0.702 |
|
| 2013 |
Wecker L, Engberg ME, Philpot RM, Lambert CS, Kang CW, Antilla JC, Bickford PC, Hudson CE, Zesiewicz TA, Rowell PP. Neuronal nicotinic receptor agonists improve gait and balance in olivocerebellar ataxia. Neuropharmacology. 73: 75-86. PMID 23711550 DOI: 10.1016/J.Neuropharm.2013.05.016 |
0.617 |
|
| 2013 |
Lambert C, Philpot R, Engberg M, Wecker L. Varenicline ameliorates spatial and temporal gait deficits following 3-acetylpyridine-induced ataxia in rats Biochemical Pharmacology. 86: 1234. DOI: 10.1016/J.Bcp.2013.08.054 |
0.591 |
|
| 2012 |
Philpot RM, Engberg ME, Wecker L. Effects of nicotine exposure on locomotor activity and pCREB levels in the ventral striatum of adolescent rats. Behavioural Brain Research. 230: 62-8. PMID 22301350 DOI: 10.1016/J.Bbr.2012.01.036 |
0.682 |
|
| 2011 |
Wecker L, Engberg M, Philpot R, Lambert C, Bickford P, Hudson C. Neuronal nicotinic receptor agonists ameliorate 3-acetylpyridine-induced ataxia Biochemical Pharmacology. 82: 1041. DOI: 10.1016/J.Bcp.2011.07.047 |
0.573 |
|
| 2009 |
Philpot RM, Wecker L, Kirstein CL. Repeated ethanol exposure during adolescence alters the developmental trajectory of dopaminergic output from the nucleus accumbens septi. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 27: 805-15. PMID 19712739 DOI: 10.1016/J.Ijdevneu.2009.08.009 |
0.761 |
|
| 2008 |
Philpot RM, Wecker L. Dependence of adolescent novelty-seeking behavior on response phenotype and effects of apparatus scaling. Behavioral Neuroscience. 122: 861-75. PMID 18729640 DOI: 10.1037/0735-7044.122.4.861 |
0.653 |
|
| 2004 |
Stansfield KH, Philpot RM, Kirstein CL. An animal model of sensation seeking: the adolescent rat. Annals of the New York Academy of Sciences. 1021: 453-8. PMID 15251928 DOI: 10.1196/Annals.1308.063 |
0.77 |
|
| 2004 |
Philpot R, Kirstein C. Developmental differences in the accumbal dopaminergic response to repeated ethanol exposure. Annals of the New York Academy of Sciences. 1021: 422-6. PMID 15251921 DOI: 10.1196/Annals.1308.056 |
0.718 |
|
| 2004 |
Vila JL, Philpot RM, Kirstein CL. Grid crossing: inability to compare activity levels between adolescent and adult rats. Annals of the New York Academy of Sciences. 1021: 418-21. PMID 15251920 DOI: 10.1196/Annals.1308.055 |
0.684 |
|
| 2004 |
Torrella TA, Badanich KA, Philpot RM, Kirstein CL, Wecker L. Developmental differences in nicotine place conditioning. Annals of the New York Academy of Sciences. 1021: 399-403. PMID 15251917 DOI: 10.1196/Annals.1308.052 |
0.734 |
|
| 2003 |
Philpot RM, Badanich KA, Kirstein CL. Place conditioning: age-related changes in the rewarding and aversive effects of alcohol. Alcoholism, Clinical and Experimental Research. 27: 593-9. PMID 12711921 DOI: 10.1111/J.1530-0277.2003.Tb04395.X |
0.75 |
|
| 2001 |
Philpot RM, McQuown S, Kirstein CL. Stereotaxic localization of the developing nucleus accumbens septi. Brain Research. Developmental Brain Research. 130: 149-53. PMID 11557105 DOI: 10.1016/S0165-3806(01)00225-5 |
0.694 |
|
| 2000 |
Bjugstad KB, Flitter WD, Garland WA, Philpot RM, Kirstein CL, Arendash GW. CPI-1189 prevents apoptosis and reduces glial fibrillary acidic protein immunostaining in a TNF-alpha infusion model for AIDS dementia complex. Journal of Neurovirology. 6: 478-91. PMID 11175320 DOI: 10.3109/13550280009091948 |
0.601 |
|
| 1999 |
Donovan DM, Miner LL, Perry MP, Revay RS, Sharpe LG, Przedborski S, Kostic V, Philpot RM, Kirstein CL, Rothman RB, Schindler CW, Uhl GR. Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression. Brain Research. Molecular Brain Research. 73: 37-49. PMID 10581396 DOI: 10.1016/S0169-328X(99)00235-1 |
0.657 |
|
| 1999 |
Philpot RM, Kirstein CL. Repeated cocaine exposure: effects on catecholamines in the nucleus accumbens septi of periadolescent animals. Pharmacology, Biochemistry, and Behavior. 62: 465-72. PMID 10080238 DOI: 10.1016/S0091-3057(98)00198-1 |
0.68 |
|
| 1998 |
Philpot RM, Kirstein CL. The effects of repeated alcohol exposure on the neurochemistry of the periadolescent nucleus accumbens septi. Neuroreport. 9: 1359-63. PMID 9631429 DOI: 10.1097/00001756-199805110-00020 |
0.718 |
|
| 1997 |
Kirstein CL, Philpot RM, Dark T. Fetal alcohol syndrome: early olfactory learning as a model system to study neurobehavioral deficits. The International Journal of Neuroscience. 89: 119-32. PMID 9134450 DOI: 10.3109/00207459708988467 |
0.657 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2014 |
Grieco JC, Ciarlone SL, Gieron-Korthals M, Schoenberg MR, Smith AG, Philpot RM, Heussler HS, Banko JL, Weeber EJ. An open-label pilot trial of minocycline in children as a treatment for Angelman syndrome. Bmc Neurology. 14: 232. PMID 25491305 DOI: 10.1186/S12883-014-0232-X |
0.272 |
|
| 2020 |
Johns B, Botelho R, Philpot RM. Increasing dietary choline to prevent chemotherapy related cognitive deficits and attenuate tumor growth in MMTV‐PyVT mice. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03283 |
0.255 |
|
| 2014 |
Fernandez JW, Philpot RM, Marsh PJ, Hartney KE, Kozel FA. The need to expand access to electroconvulsive therapy: a retrospective analysis of a new academic service. Journal of Psychiatric Practice. 20: 308-15. PMID 25036588 DOI: 10.1097/01.Pra.0000452569.92449.76 |
0.217 |
|
| 2021 |
Johns BE, Ficken M, Engberg ME, Wecker L, Philpot RM. Increasing dietary choline attenuates spatial memory deficits resulting from exposure to the chemotherapeutic agents cyclophosphamide and doxorubicin. Journal of Psychopharmacology (Oxford, England). 2698811211029752. PMID 34225528 DOI: 10.1177/02698811211029752 |
0.176 |
|
| 2022 |
Botelho R, Johns B, Philpot RM. The use of choline supplementation for the prevention of chemotherapy-related cognitive impairments. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35554608 DOI: 10.1096/fasebj.2022.36.S1.R2384 |
0.173 |
|
| 1994 |
Plopper CG, Weir AJ, Nishio SJ, Chang A, Voit M, Philpot RM, Buckpitt AR. Elevated susceptibility to 4-ipomeanol cytotoxicity in immature Clara cells of neonatal rabbits. The Journal of Pharmacology and Experimental Therapeutics. 269: 867-80. PMID 8182556 |
0.164 |
|
| 1995 |
Ji CM, Cardoso WV, Gebremichael A, Philpot RM, Buckpitt AR, Plopper CG, Pinkerton KE. Pulmonary cytochrome P-450 monooxygenase system and Clara cell differentiation in rats. The American Journal of Physiology. 269: L394-402. PMID 7573474 DOI: 10.1152/Ajplung.1995.269.3.L394 |
0.151 |
|
| 1996 |
Lakritz J, Chang A, Weir A, Nishio S, Hyde D, Philpot R, Buckpitt A, Plopper C. Cellular and metabolic basis of Clara cell tolerance to multiple doses of cytochrome P450-activated cytotoxicants. I: Bronchiolar epithelial reorganization and expression of cytochrome P450 monooxygenases in mice exposed to multiple doses of naphthalene. The Journal of Pharmacology and Experimental Therapeutics. 278: 1408-18. PMID 8819528 |
0.15 |
|
| 1987 |
Lucier GW, Nelson KG, Everson RB, Wong TK, Philpot RM, Tiernan T, Taylor M, Sunahara GI. Placental markers of human exposure to polychlorinated biphenyls and polychlorinated dibenzofurans. Environmental Health Perspectives. 76: 79-87. PMID 2834196 DOI: 10.1289/Ehp.877679 |
0.127 |
|
| 1972 |
Philpot RM, Hodgson E. The production and modification of cytochrome P-450 difference spectra by in vivo administration of methylenedioxyphenyl compounds Chemico-Biological Interactions. 4: 185-194. PMID 5008936 DOI: 10.1016/0009-2797(72)90013-0 |
0.124 |
|
| 1978 |
Mukhtar H, Philpot RM, Bend JR. The postnatal development of microsomal epoxide hydrase, cytosolic glutathione S-transferase, and mitochondrial and microsomal cytochrome P-450 in adrenals and ovaries of female rats Drug Metabolism and Disposition. 6: 577-583. PMID 30608 |
0.123 |
|
| 1995 |
Buckpitt A, Chang AM, Weir A, Van Winkle L, Duan X, Philpot R, Plopper C. Relationship of cytochrome P450 activity to Clara cell cytotoxicity. IV. Metabolism of naphthalene and naphthalene oxide in microdissected airways from mice, rats, and hamsters. Molecular Pharmacology. 47: 74-81. PMID 7838135 |
0.121 |
|
| 1983 |
Plopper CG, Alley JL, Serabjitsingh CJ, Philpot RM. Cytodifferentiation of the nonciliated bronchiolar epithelial (Clara) cell during rabbit lung maturation: an ultrastructural and morphometric study. The American Journal of Anatomy. 167: 329-57. PMID 6881072 DOI: 10.1002/aja.1001670305 |
0.12 |
|
| 1993 |
Plopper CG, Weir AJ, Morin D, Chang A, Philpot RM, Buckpitt AR. Postnatal changes in the expression and distribution of pulmonary cytochrome P450 monooxygenases during Clara cell differentiation in rabbits. Molecular Pharmacology. 44: 51-61. PMID 8341279 |
0.116 |
|
| 1993 |
Verschoyle RD, Philpot RM, Wolf CR, Dinsdale D. CYP4B1 activates 4-ipomeanol in rat lung. Toxicology and Applied Pharmacology. 123: 193-8. PMID 8248926 DOI: 10.1006/taap.1993.1237 |
0.112 |
|
| 1978 |
Mukhtar H, Philpot RM, Bend JR. Epoxide-metabolizing enzyme activities and cytochrome P-450 content of rat ovaries during pregnancy Biochemical and Biophysical Research Communications. 81: 89-98. PMID 656106 DOI: 10.1016/0006-291X(78)91634-0 |
0.106 |
|
| 1994 |
Hines RN, Cashman JR, Philpot RM, Williams DE, Ziegler DM. The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression. Toxicology and Applied Pharmacology. 125: 1-6. PMID 8128486 DOI: 10.1006/Taap.1994.1042 |
0.106 |
|
| 1980 |
Lui EMK, Slaughter SR, Philpot RM, Lucier GW. Cadmium-sensitive cytochrome P-450 in rat liver Federation Proceedings. 39: 3154. |
0.102 |
|
| 1997 |
Fanucchi MV, Murphy ME, Buckpitt AR, Philpot RM, Plopper CG. Pulmonary cytochrome P450 monooxygenase and Clara cell differentiation in mice. American Journal of Respiratory Cell and Molecular Biology. 17: 302-14. PMID 9308917 DOI: 10.1165/ajrcmb.17.3.2774 |
0.101 |
|
| 1982 |
Lui EM, Slaughter SR, Philpot RM, Lucier GW. Endocrine regulation of cadmium-sensitive cytochrome P-450 in rat liver. Molecular Pharmacology. 22: 795-802. PMID 6897560 |
0.1 |
|
| 1980 |
Orton TC, Philpot RM. Heterogeneity of testosterone hydroxylases in rat and rabbit liver microsomes. Quantification of major hydroxytesterone metabolites by a thin layer radiochromatographic procedure Journal of Steroid Biochemistry. 13: 873-879. PMID 7464134 DOI: 10.1016/0022-4731(80)90160-0 |
0.099 |
|
| 1998 |
Lang DH, Yeung CK, Peter RM, Ibarra C, Gasser R, Itagaki K, Philpot RM, Rettie AE. Isoform specificity of trimethylamine N-oxygenation by human flavin-containing monooxygenase (FMO) and P450 enzymes: selective catalysis by FMO3. Biochemical Pharmacology. 56: 1005-12. PMID 9776311 DOI: 10.1016/S0006-2952(98)00218-4 |
0.099 |
|
| 1995 |
Kitzler J, Hill E, Hardman R, Reddy N, Philpot R, Eling TE. Analysis and quantitation of splicing variants of the TPA-inducible PGHS-1 mRNA in rat tracheal epithelial cells. Archives of Biochemistry and Biophysics. 316: 856-63. PMID 7864644 DOI: 10.1006/abbi.1995.1115 |
0.097 |
|
| 1991 |
Adams DR, Jones AM, Plopper CG, Serabjit-Singh CJ, Philpot RM. Distribution of cytochrome P-450 monoxygenase enzymes in the nasal mucosa of hamster and rat. The American Journal of Anatomy. 190: 291-8. PMID 2048556 DOI: 10.1002/aja.1001900309 |
0.094 |
|
| 1975 |
Philpot RM, Bend JR. Benzpyrene hydroxylase activity in hepatic microsomal and solubilized systems containing rabbit or rat cytochrome P-448 or P-450 Life Sciences. 16: 985-997. PMID 1128164 DOI: 10.1016/0024-3205(75)90014-4 |
0.094 |
|
| 1973 |
Hodgson E, Philpot RM, Baker RC, Mailman RB. Effect of synergists on drug metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 1: 391-401. PMID 4149410 |
0.093 |
|
| 1971 |
Abernathy CO, Philpot RM, Guthrie FE, Hodgson E. Inductive effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane(DDT), phenobarbital, and benzpyrene on microsomal cytochrome P450, ethyl isocyanide spectra, and metabolism in vivo of zoxazolamine and hexobarbital in the mouse Biochemical Pharmacology. 20: 2395-2400. PMID 5163150 DOI: 10.1016/0006-2952(71)90239-5 |
0.092 |
|
| 1996 |
Krause RJ, Ripp SL, Sausen PJ, Overby LH, Philpot RM, Elfarra AA. Characterization of the methionine S-oxidase activity of rat liver and kidney microsomes: immunochemical and kinetic evidence for FMO3 being the major catalyst. Archives of Biochemistry and Biophysics. 333: 109-16. PMID 8806760 DOI: 10.1006/abbi.1996.0370 |
0.092 |
|
| 1992 |
Wolff NA, Philpot RM, Miller DS, Pritchard JB. Functional expression of renal organic anion transport in Xenopus laevis oocytes. Molecular and Cellular Biochemistry. 114: 35-41. PMID 1281263 DOI: 10.1007/BF00240295 |
0.091 |
|
| 1997 |
Kitzler J, Hardman R, Hill E, Reddy N, Philpot R, Eling TE. Cloning and sequencing of prostaglandin H synthetase from rat tracheal epithelial cells: structural evidence that a TPA regulated mRNA codes for the rat ortholog of murine PHS-1. Advances in Experimental Medicine and Biology. 400: 65-70. PMID 9547538 |
0.09 |
|
| 1991 |
Kedzie KM, Philpot RM, Halpert JR. Functional expression of mammalian cytochromes P450IIB in the yeast Saccharomyces cerevisiae. Archives of Biochemistry and Biophysics. 291: 176-86. PMID 1929429 DOI: 10.1016/0003-9861(91)90121-X |
0.089 |
|
| 1998 |
Rainov NG, Dobberstein KU, Sena-Esteves M, Herrlinger U, Kramm CM, Philpot RM, Hilton J, Chiocca EA, Breakefield XO. New prodrug activation gene therapy for cancer using cytochrome P450 4B1 and 2-aminoanthracene/4-ipomeanol. Human Gene Therapy. 9: 1261-73. PMID 9650611 DOI: 10.1089/Hum.1998.9.9-1261 |
0.088 |
|
| 1976 |
Chhabra RS, Tredger JM, Philpot RM, Fouts JR. Relationship between induction of aryl hydrocarbon hydroxylase and de novo synthesis of cytochrome P-448 (P1-450) in mice. Chemico-Biological Interactions. 15: 21-31. PMID 971515 DOI: 10.1016/0009-2797(76)90125-3 |
0.085 |
|
| 1998 |
Halpert JR, Domanski TL, Adali O, Biagini CP, Cosme J, Dierks EA, Johnson EF, Jones JP, Ortiz de Montellano P, Philpot RM, Sibbesen O, Wyatt WK, Zheng Z. Structure-function of cytochromes P450 and flavin-containing monooxygenases: implications for drug metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 26: 1223-31. PMID 9860932 |
0.084 |
|
| 1995 |
Overby LH, Buckpitt AR, Lawton MP, Atta-Asafo-Adjei E, Schulze J, Philpot RM. Characterization of flavin-containing monooxygenase 5 (FMO5) cloned from human and guinea pig: evidence that the unique catalytic properties of FMO5 are not confined to the rabbit ortholog. Archives of Biochemistry and Biophysics. 317: 275-84. PMID 7872795 DOI: 10.1006/abbi.1995.1163 |
0.082 |
|
| 1979 |
Mukhtar H, Elmamlouk TH, Philpot RM, Bend JR. Rat hepatic nuclear cytochrome P-450 and epoxide hydrase in membranes prepared by two methods: similarities with the microsomal enzymes Molecular Pharmacology. 15: 192-196. PMID 423889 |
0.082 |
|
| 1984 |
Serabjit-Singh CJ, Bend JR, Philpot RM. Characterization of hepatic NADPH cytochrome P-450 reductase from stingray and comparison with hepatic reductases from skate, rabbit and rat Federation Proceedings. 43: no. 1509. |
0.082 |
|
| 1998 |
Adali O, Carver GC, Philpot RM. Modulation of human flavin-containing monooxygenase 3 activity by tricyclic antidepressants and other agents: importance of residue 428. Archives of Biochemistry and Biophysics. 358: 92-7. PMID 9750169 DOI: 10.1006/abbi.1998.0835 |
0.08 |
|
| 1991 |
Czerwinski M, McLemore TL, Philpot RM, Nhamburo PT, Korzekwa K, Gelboin HV, Gonzalez FJ. Metabolic activation of 4-ipomeanol by complementary DNA-expressed human cytochromes P-450: evidence for species-specific metabolism. Cancer Research. 51: 4636-8. PMID 1651809 |
0.075 |
|
| 1971 |
Philpot RM, Hodgson E. A cytochrome P-450-piperonyl butoxide spectrum similar to that produced by ethyl isocyanide Life Sciences. 10: 503-512. PMID 4397161 DOI: 10.1016/0024-3205(71)90124-X |
0.072 |
|
| 1989 |
Gasser R, Philpot RM. Primary structures of cytochrome P-450 isozyme 5 from rabbit and rat and regulation of species-dependent expression and induction in lung and liver: identification of cytochrome P-450 gene subfamily IVB. Molecular Pharmacology. 35: 617-25. PMID 2725471 |
0.072 |
|
| 1983 |
Robertson IG, Serabjit-Singh C, Croft JE, Philpot RM. The relationship between increases in the hepatic content of cytochrome P-450, form 5, and in the metabolism of aromatic amines to mutagenic products following treatment of rabbits with phenobarbital. Molecular Pharmacology. 24: 156-62. PMID 6865923 |
0.07 |
|
| 1996 |
Blake BL, Philpot RM, Levi PE, Hodgson E. Xenobiotic biotransforming enzymes in the central nervous system: an isoform of flavin-containing monooxygenase (FMO4) is expressed in rabbit brain. Chemico-Biological Interactions. 99: 253-61. PMID 8620573 DOI: 10.1016/0009-2797(95)03679-2 |
0.07 |
|
| 1995 |
Rettie AE, Sheffels PR, Korzekwa KR, Gonzalez FJ, Philpot RM, Baillie TA. CYP4 isozyme specificity and the relationship between omega-hydroxylation and terminal desaturation of valproic acid. Biochemistry. 34: 7889-95. PMID 7794900 DOI: 10.1021/Bi00024A013 |
0.069 |
|
| 1997 |
Falls JG, Cherrington NJ, Clements KM, Philpot RM, Levi PE, Rose RL, Hodgson E. Molecular cloning, sequencing, and expression in Escherichia coli of mouse flavin-containing monooxygenase 3 (FMO3): comparison with the human isoform. Archives of Biochemistry and Biophysics. 347: 9-18. PMID 9344459 DOI: 10.1006/Abbi.1997.0322 |
0.068 |
|
| 1972 |
Philpot RM, Hodgson E. Differences in the cytochrome P-450S from resistant and susceptible house flies Chemico-Biological Interactions. 4: 399-408. PMID 5030585 DOI: 10.1016/0009-2797(72)90060-9 |
0.068 |
|
| 1990 |
Strum JM, Ito T, Philpot RM, DeSanti AM, McDowell EM. The immunocytochemical detection of cytochrome P-450 monooxygenase in the lungs of fetal, neonatal, and adult hamsters. American Journal of Respiratory Cell and Molecular Biology. 2: 493-501. PMID 2112008 DOI: 10.1165/ajrcmb/2.6.493 |
0.067 |
|
| 1984 |
Philpot RM, Smith BR. Role of cytochrome P-450 and related enzymes in the pulmonary metabolism of xenobiotics. Environmental Health Perspectives. 55: 359-67. PMID 6376107 |
0.067 |
|
| 1995 |
Johnson ES, Overby L, Philpot R. Detection of antibodies to avian leukosis/sarcoma viruses and reticuloendotheliosis viruses in humans by western blot assay. Cancer Detection and Prevention. 19: 472-86. PMID 8925516 |
0.067 |
|
| 1982 |
Wolf CR, Statham CN, McMenamin MG, Bend JR, Boyd MR, Philpot RM. The relationship between the catalytic activities of rabbit pulmonary cytochrome P-450 isozymes and the lung-specific toxicity of the furan derivative, 4-ipomeanol. Molecular Pharmacology. 22: 738-44. PMID 7155130 |
0.066 |
|
| 1979 |
Maier P, Philpot RM, Mohn GR, Malling HV. Influence of subcellular fractions of mammalian testes on the mutagenic activity of nitrofurans toward Escherichia coli; presence of a co-mutagen-like factor. Mutation Research. 63: 233-43. PMID 118378 DOI: 10.1016/0027-5107(79)90056-3 |
0.066 |
|
| 1979 |
Patel JM, Wolf CR, Philpot RM. Interaction of 4-methylbenzaldehyde with rabbit pulmonary cytochrome p-450 in the intact animal, microsomes, and purified systems. Destructive and protective reactions Biochemical Pharmacology. 28: 2031-2036. PMID 475845 DOI: 10.1016/0006-2952(79)90220-X |
0.066 |
|
| 1995 |
Castonguay A, Overby L, Nettesheim P, Clark GC, Philpot RM. Expression of xenobiotic-metabolizing enzymes in cultured rat tracheal epithelial cells. Environmental Health Perspectives. 103: 254-8. PMID 7768226 DOI: 10.1289/Ehp.95103254 |
0.065 |
|
| 1986 |
Wong TK, Domin BA, Bent PE, Blanton TE, Anderson MW, Philpot RM. Correlation of placental microsomal activities with protein detected by antibodies to rabbit cytochrome P-450 isozyme 6 in preparations from humans exposed to polychlorinated biphenyls, quaterphenyls, and dibenzofurans. Cancer Research. 46: 999-1004. PMID 3079671 |
0.064 |
|
| 1978 |
Wolf CR, Szutowski MM, Ball LM, Philpot RM. The rabbit pulmonary monooxygenase system: Characteristics and activities of two forms of pulmonary cytochrome P-450 Chemico-Biological Interactions. 21: 29-43. PMID 96944 DOI: 10.1016/0009-2797(78)90066-2 |
0.064 |
|
| 1974 |
Chhabra RS, Tredger JM, Philpot RM, Fouts JR. Selection of inducers: an important factor in characterizing genetic differences to induction of aryl hydrocarbon hydroxylase in strains of mice. Life Sciences. 15: 123-30. PMID 4549901 DOI: 10.1016/0024-3205(74)90200-8 |
0.063 |
|
| 1983 |
Pohl RJ, Serabjit-Singh CJ, Slaughter SR, Albro PW, Fouts JR, Philpot RM. Hepatic microsomal NADPH-cytochrome P-450 reductase from little skate, Raja erinacea. Comparison of thermolability and other molecular properties with a mammalian enzyme. Chemico-Biological Interactions. 45: 283-94. PMID 6411368 DOI: 10.1016/0009-2797(83)90075-3 |
0.063 |
|
| 1986 |
Domin BA, Philpot RM. The effect of substrate on the expression of activity catalyzed by cytochrome P-450: metabolism mediated by rabbit isozyme 6 in pulmonary microsomal and reconstituted monooxygenase systems. Archives of Biochemistry and Biophysics. 246: 128-42. PMID 3963817 DOI: 10.1016/0003-9861(86)90456-X |
0.06 |
|
| 1986 |
Waskell L, Canova-Davis E, Philpot R, Parandoush Z, Chiang JY. Identification of the enzymes catalyzing metabolism of methoxyflurane. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 14: 643-8. PMID 2877820 |
0.059 |
|
| 1993 |
Pernecky SJ, Larson JR, Philpot RM, Coon MJ. Expression of truncated forms of liver microsomal P450 cytochromes 2B4 and 2E1 in Escherichia coli: influence of NH2-terminal region on localization in cytosol and membranes. Proceedings of the National Academy of Sciences of the United States of America. 90: 2651-5. PMID 8464872 DOI: 10.1073/Pnas.90.7.2651 |
0.058 |
|
| 1994 |
Rettie AE, Lawton MP, Sadeque AJ, Meier GP, Philpot RM. Prochiral sulfoxidation as a probe for multiple forms of the microsomal flavin-containing monooxygenase: studies with rabbit FMO1, FMO2, FMO3, and FMO5 expressed in Escherichia coli. Archives of Biochemistry and Biophysics. 311: 369-77. PMID 8203899 DOI: 10.1006/Abbi.1994.1250 |
0.057 |
|
| 1998 |
Wyatt MK, Overby LH, Lawton MP, Philpot RM. Identification of amino acid residues associated with modulation of flavin-containing monooxygenase (FMO) activity by imipramine: structure/function studies with FMO1 from pig and rabbit. Biochemistry. 37: 5930-8. PMID 9558327 DOI: 10.1021/bi972622b |
0.057 |
|
| 1991 |
Chichester CH, Philpot RM, Weir AJ, Buckpitt AR, Plopper CG. Characterization of the cytochrome P-450 monooxygenase system in nonciliated bronchiolar epithelial (Clara) cells isolated from mouse lung. American Journal of Respiratory Cell and Molecular Biology. 4: 179-86. PMID 1991074 DOI: 10.1165/Ajrcmb/4.2.179 |
0.055 |
|
| 1987 |
Plopper CG, Cranz DL, Kemp L, Serabjit-Singh CJ, Philpot RM. Immunohistochemical demonstration of cytochrome P-450 monooxygenase in Clara cells throughout the tracheobronchial airways of the rabbit. Experimental Lung Research. 13: 59-68. PMID 3653045 DOI: 10.3109/01902148709064309 |
0.055 |
|
| 1984 |
Vanderslice RR, Boyd JA, Eling TE, Philpot RM. The role of cytochrome P-450 form 5 in the metabolism of 2-aminofluorene by the microsomal fraction of rabbit bladder Federation Proceedings. 43: no. 363. |
0.054 |
|
| 1980 |
Callen DF, Wolf CR, Philpot RM. Cytochrome P-450 mediated genetic activity and cytotoxicity of seven halogenated aliphatic hydrocarbons in Saccharomyces cerevisiae Mutation Research/Genetic Toxicology. 77: 55-63. PMID 6767185 DOI: 10.1016/0165-1218(80)90120-2 |
0.053 |
|
| 1994 |
Duescher RJ, Lawton MP, Philpot RM, Elfarra AA. Flavin-containing monooxygenase (FMO)-dependent metabolism of methionine and evidence for FMO3 being the major FMO involved in methionine sulfoxidation in rabbit liver and kidney microsomes. The Journal of Biological Chemistry. 269: 17525-30. PMID 8021260 |
0.053 |
|
| 1972 |
Philpot RM, Hodgson E. The effect of piperonyl butoxide concentration on the formation of cytochrome P-450 difference spectra in hepatic microsomes from mice Molecular Pharmacology. 8: 204-214. PMID 4402004 |
0.053 |
|
| 1971 |
Folsom MD, Philpot RM, Hodgson E. The effect of enzymes and other reagents on NADPH oxidation and oxygen uptake by microsomal preparations from the housefly, Musca domestica Comparative Biochemistry and Physiology -- Part B: Biochemistry And. 39: 589-597. PMID 4399335 DOI: 10.1016/0305-0491(71)90203-3 |
0.053 |
|
| 1974 |
Philpot RM, Bend JR. Catalytic activity of rabbit hepatic cytochrome P 448 induced by 3 methylcholanthrene Pharmacologist. 16: 738. |
0.052 |
|
| 1984 |
Domin BA, Serabjit-Singh CJ, Philpot RM. Quantitation of rabbit cytochrome P-450, form 2, in microsomal preparations bound directly to nitrocellulose paper using a modified peroxidase-immunostaining procedure. Analytical Biochemistry. 136: 390-6. PMID 6426342 DOI: 10.1016/0003-2697(84)90234-3 |
0.052 |
|
| 1983 |
Duthu GS, Nestor MS, Berliner JA, Philpot RM, Hankinson O. Characterization of NADPH-cytochrome P-450 reductase in a mouse hepatoma cell line. Cancer Letters. 18: 237-43. PMID 6303557 DOI: 10.1016/0304-3835(83)90231-8 |
0.051 |
|
| 1978 |
Callen DF, Wolf CR, Philpot RM. Cumene hydroperoxide and yeast cytochrome P-450: Spectral interactions and effect on the genetic activity of promutagens Biochemical and Biophysical Research Communications. 83: 14-20. PMID 358974 DOI: 10.1016/0006-291X(78)90391-1 |
0.051 |
|
| 1985 |
Vanderslice RR, Boyd JA, Eling TE, Philpot RM. The cytochrome P-450 monooxygenase system of rabbit bladder mucosa: enzyme components and isozyme 5-dependent metabolism of 2-aminofluorene. Cancer Research. 45: 5851-8. PMID 4053055 |
0.05 |
|
| 1979 |
Wolf CR, Smith BR, Ball LM, Serabjit-Singh C, Bend JR, Philpot RM. The rabbit pulmonary monooxygenase system. Catalytic differences between two purified forms of cytochrome P-450 in the metabolism of benzo(a)pyrene Journal of Biological Chemistry. 254: 3658-3663. PMID 429376 |
0.048 |
|
| 1985 |
Parandoosh Z, Philpot RM. Purification of phenobarbital-inducible isozymes of cytochrome P-450 from rabbit hepatic microsomal preparations Federation Proceedings. 44: No. 4665. |
0.048 |
|
| 1976 |
Pohl RJ, Philpot RM, Fouts JR. Cytochrome P 450 content and mixed function oxidase activity in microsomes isolated from mouse skin Drug Metabolism and Disposition. 4: 442-450. PMID 10143 |
0.048 |
|
| 1974 |
Pohl RJ, Philpot RM, Fouts JR. Cytochrome P450 content and mixed function oxidase activity in microsomes isolated from mouse skin Pharmacologist. 16: no.744. |
0.048 |
|
| 1977 |
Callen DF, Philpot RM. Cytochrome P-450 and the activation of promutagens in Saccharomyces cerevisiae Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 45: 309-324. PMID 339069 DOI: 10.1016/0027-5107(77)90141-5 |
0.047 |
|
| 1985 |
Tynes RE, Sabourin PJ, Hodgson E, Philpot RM. Pulmonary forms of rabbit and mouse microsomal flavin-containing monooxygenase (FMO) have unique primary amine N-hydroxylase activity Federation Proceedings. 44: No. 4715. |
0.047 |
|
| 1999 |
Ripp SL, Itagaki K, Philpot RM, Elfarra AA. Methionine S-oxidation in human and rabbit liver microsomes: evidence for a high-affinity methionine S-oxidase activity that is distinct from flavin-containing monooxygenase 3. Archives of Biochemistry and Biophysics. 367: 322-32. PMID 10395751 DOI: 10.1006/abbi.1999.1247 |
0.047 |
|
| 1990 |
Ferris NP, Kitching RP, Oxtoby JM, Philpot RM, Rendle R. Use of inactivated foot-and-mouth disease virus antigen in liquid-phase blocking ELISA. Journal of Virological Methods. 29: 33-41. PMID 2170435 DOI: 10.1016/0166-0934(90)90005-Z |
0.046 |
|
| 1998 |
Cherrington NJ, Falls JG, Rose RL, Clements KM, Philpot RM, Levi PE, Hodgson E. Molecular cloning, sequence, and expression of mouse flavin-containing monooxygenases 1 and 5 (FMO1 and FMO5). Journal of Biochemical and Molecular Toxicology. 12: 205-12. PMID 9580872 DOI: 10.1002/(Sici)1099-0461(1998)12:4<205::Aid-Jbt2>3.0.Co;2-P |
0.046 |
|
| 1981 |
Bend JR, Smith BR, Ball LM, Plummer JL, Wolf CR, Philpot RM, Devereux TR, Fouts JR. Metabolism of benzo(a)pyrene and benzo(a)pyrene 4,5-oxide in rabbit lung Advances in Experimental Medicine and Biology. 136: 541-554. PMID 6283815 DOI: 10.1007/978-1-4757-0674-1_40 |
0.046 |
|
| 1980 |
Serabjit-Singh CJ, Wolf CR, Philpot RM, Plopper CG. Cytochrome P-450: Localization in rabbit lung Science. 207: 1469-1470. PMID 6767272 DOI: 10.1126/Science.6767272 |
0.045 |
|
| 2015 |
Philpot R. Critical pedagogies in PETE: An antipodean perspective Journal of Teaching in Physical Education. 34: 316-332. DOI: 10.1123/jtpe.2014-0054 |
0.045 |
|
| 1995 |
Zeldin DC, Plitman JD, Kobayashi J, Miller RF, Snapper JR, Falck JR, Szarek JL, Philpot RM, Capdevila JH. The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance. The Journal of Clinical Investigation. 95: 2150-60. PMID 7738183 DOI: 10.1172/Jci117904 |
0.044 |
|
| 1977 |
Philpot RM, Serabjit Singh CJ. Spectral characterization of purified hepatic cytochrome P 450 from 3 methylcholanthrene treated and untreated rabbits Federation Proceedings. 36: No.3802. |
0.044 |
|
| 1996 |
Itagaki K, Carver GT, Philpot RM. Expression and characterization of a modified flavin-containing monooxygenase 4 from humans. The Journal of Biological Chemistry. 271: 20102-7. PMID 8702731 DOI: 10.1074/jbc.271.33.20102 |
0.044 |
|
| 1999 |
Adali O, Carver GC, Philpot RM. The effect of arginine-428 mutation on modulation of activity of human liver flavin monooxygenase 3 (FMO3) by imipramine and chlorpromazine. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Fã¼R Toxikologische Pathologie. 51: 271-6. PMID 10445381 DOI: 10.1016/S0940-2993(99)80004-9 |
0.043 |
|
| 2011 |
Philpot R. Sigma receptors Xpharm: the Comprehensive Pharmacology Reference. 1-1. DOI: 10.1016/B978-008055232-3.63781-X |
0.043 |
|
| 1977 |
Elmamlouk TH, Philpot RM, Bend JR. Separation of two forms of cytochrome P-450 from hepatic microsomes of 1,2,3,4-dibenzanthracene (DBA) pretreated little skates (Raja Erinacea) Pharmacologist. 19: No.187. |
0.042 |
|
| 1997 |
Haining RL, Hunter AP, Sadeque AJ, Philpot RM, Rettie AE. Baculovirus-mediated expression and purification of human FMO3: catalytic, immunochemical, and structural characterization. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 25: 790-7. PMID 9224773 |
0.042 |
|
| 1983 |
Serabjit-Singh CJ, Albro PW, Robertson IG, Philpot RM. Interactions between xenobiotics that increase or decrease the levels of cytochrome P-450 isozymes in rabbit lung and liver. The Journal of Biological Chemistry. 258: 12827-34. PMID 6415056 |
0.041 |
|
| 1982 |
Groft JE, Philpot RM. The effect of dexamethasone and deoxycorticosterone treatment on the rabbit pulmonary monooxygenase system Federation Proceedings. 41: 8542. |
0.041 |
|
| 1986 |
Croft JE, Harrelson WG, Parandoosh Z, Philpot RM. Unique properties of NADPH- and NADH-dependent metabolism of p-nitroanisole catalyzed by cytochrome P-450 isozyme 2 in pulmonary and hepatic microsomal preparations from rabbits. Chemico-Biological Interactions. 57: 143-60. PMID 3955788 DOI: 10.1016/0009-2797(86)90034-7 |
0.041 |
|
| 1987 |
Parandoosh Z, Fujita VS, Coon MJ, Philpot RM. Cytochrome P-450 isozymes 2 and 5 in rabbit lung and liver. Comparisons of structure and inducibility. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 15: 59-67. PMID 2881760 |
0.041 |
|
| 1980 |
Ball LM, Philpot RM, Bend JR. Partial purification and spectral characterization of constitutive form of cytochrome P-450 from the liver of the little skate, Raja erinacea, a marine elasmobranch Pharmacologist. 22: No. 571. |
0.041 |
|
| 1992 |
Kumagai Y, Lin LY, Philpot RM, Yamada H, Oguri K, Yoshimura H, Cho AK. Regiochemical differences in cytochrome P450 isozymes responsible for the oxidation of methylenedioxyphenyl groups by rabbit liver. Molecular Pharmacology. 42: 695-702. PMID 1435745 |
0.04 |
|
| 1982 |
Devereux TR, Diliberto JJ, Philpot RM, Fouts JR. NADPH- and NADH-mediated metabolism of 7-ethoxycoumarin and p-nitroanisole in alveolar type II and Clara cell microsomes isolated from rabbit lung Federation Proceedings. 41: 7425. |
0.04 |
|
| 1984 |
Domin BA, Carver GC, Bent PE, Philpot RM. Metabolism of benzo(a)pyrene by cytochrome P-450, form 6, in rabbit lung Federation Proceedings. 43: no. 1511. |
0.04 |
|
| 1981 |
Robertson LG, Philpot RM, Zeiger E, Wolf CR. Specificity of rabbit pulmonary cytochrome P-450 isozymes in the activation of several aromatic amines and aflatoxin B1. Molecular Pharmacology. 20: 662-8. PMID 6799775 |
0.039 |
|
| 1999 |
Biagini CP, Philpot RM, Célier CM. Nonsubstrate recognition site residues are involved in testosterone hydroxylation by cytochrome P450 CYP 2C11. Archives of Biochemistry and Biophysics. 361: 309-14. PMID 9882461 DOI: 10.1006/abbi.1998.1003 |
0.039 |
|
| 1978 |
Wolf CR, Ball L, Bend JR, Philpot RM. The metabolism of benzo(a)pyrene in rabbit pulmonary monooxygenase systems reconstituted from purified components: activities of cytochrome P-450 I and II Federation Proceedings. 37: No. 2263. |
0.039 |
|
| 1980 |
Kohli KK, Philpot RM, Albro PW, McKinney JD. Induction of different species of cytochrome P-450 by coplanar and noncoplanar isomers of hexachlorobiphenyl Life Sciences. 26: 945-952. PMID 6771479 DOI: 10.1016/0024-3205(80)90115-0 |
0.037 |
|
| 1993 |
Ryan R, Grimm SW, Kedzie KM, Halpert JR, Philpot RM. Cloning, sequencing, and functional studies of phenobarbital-inducible forms of cytochrome P450 2B and 4B expressed in rabbit kidney. Archives of Biochemistry and Biophysics. 304: 454-63. PMID 8346920 DOI: 10.1006/Abbi.1993.1375 |
0.037 |
|
| 1985 |
Aune T, Vanderslice RR, Croft JE, Dybing E, Bend JR, Philpot RM. Deacetylation to 2-aminofluorene as a major initial reaction in the microsomal metabolism of 2-acetylaminofluorene to mutagenic products in preparations from rabbit lung and liver. Cancer Research. 45: 5859-66. PMID 4053056 |
0.037 |
|
| 1990 |
Ferris NP, Philpot RM, Oxtoby JM, Armstrong RM. Freeze-drying foot-and-mouth disease virus antigens. II. For use in the ELISA. Journal of Virological Methods. 30: 183-95. PMID 2175750 DOI: 10.1016/0166-0934(90)90019-C |
0.036 |
|
| 1992 |
Overby LH, Nishio S, Weir A, Carver GT, Plopper CG, Philpot RM. Distribution of cytochrome P450 1A1 and NADPH-cytochrome P450 reductase in lungs of rabbits treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin: ultrastructural immunolocalization and in situ hybridization. Molecular Pharmacology. 41: 1039-46. PMID 1614408 |
0.035 |
|
| 1990 |
Lawton MP, Gasser R, Tynes RE, Hodgson E, Philpot RM. The flavin-containing monooxygenase enzymes expressed in rabbit liver and lung are products of related but distinctly different genes. The Journal of Biological Chemistry. 265: 5855-61. PMID 2318837 |
0.035 |
|
| 1993 |
Lawton MP, Philpot RM. Molecular genetics of the flavin-dependent monooxygenases. Pharmacogenetics. 3: 40-4. PMID 8485586 |
0.035 |
|
| 1985 |
Domin BA, Philpot RM. NADPH cytochrome P-450 reductase and substrate determine the extent to which the catalytic potential of cytochrome P-450, isozyme 6, is expressed in the rabbit pulmonary microsomal fraction Federation Proceedings. 44: No. 6178. |
0.034 |
|
| 1970 |
Folsom MD, Hansen LG, Philpot RM, Yang RSH, Dauterman WC, Hodgson E. Biochemical characteristics of microsomal preparations from diazinon-resistant and -susceptible houseflies Life Sciences. 9: 869-875. PMID 4394569 DOI: 10.1016/0024-3205(70)90056-1 |
0.034 |
|
| 1983 |
Slaughter SR, Statham CN, Philpot RM, Boyd MR. Covalent binding of metabolites of 4-ipomeanol to rabbit pulmonary and hepatic microsomal proteins and to the enzymes of the pulmonary cytochrome P-450-dependent monooxygenase system. The Journal of Pharmacology and Experimental Therapeutics. 224: 252-7. PMID 6848746 |
0.034 |
|
| 1978 |
Callen DF, Philpot RM, Ong TM. Cytochrome P-450 and the activation of aflatoxin B1 in Saccharomyces cerevisiae Mutation Research. 53: No. 34. DOI: 10.1016/0165-1161(78)90412-0 |
0.034 |
|
| 1999 |
Adali O, Philpot RM. Characterization and structure-function studies of human liver flavin monooxygenase isozyme 3 (FM03) Turkish Journal of Zoology. 23: 45-52. |
0.034 |
|
| 1986 |
Tynes RE, Sabourin PJ, Hodgson E, Philpot RM. Formation of hydrogen peroxide and N-hydroxylated amines catalyzed by pulmonary flavin-containing monooxygenases in the presence of primary alkylamines. Archives of Biochemistry and Biophysics. 251: 654-64. PMID 3800392 DOI: 10.1016/0003-9861(86)90375-9 |
0.033 |
|
| 1980 |
Franklin MR, Wolf CR, Serabjit-Singh C, Philpot RM. Quantitation of two forms of pulmonary cytochrome P-450 in microsomes, using substrate specificities Molecular Pharmacology. 17: 415-420. PMID 7393217 |
0.033 |
|
| 2004 |
Morwood K, Bourne H, Philpot R, Gold M, Gillis D, Benson EM. Phenotypic variability: Clinical presentation between the 6th year and the 60th year in a family with X-linked agammaglobulinemia [1] Journal of Allergy and Clinical Immunology. 113: 783-785. PMID 15112668 DOI: 10.1016/j.jaci.2003.10.061 |
0.033 |
|
| 1994 |
Knickle LC, Philpot RM, Bend JR. N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo. The Journal of Pharmacology and Experimental Therapeutics. 270: 377-85. PMID 8035335 |
0.033 |
|
| 1992 |
Nikbakht KN, Lawton MP, Philpot RM. Guinea pig or rabbit lung flavin-containing monooxygenases with distinct mobilities in SDS-PAGE are allelic variants that differ at only two positions. Pharmacogenetics. 2: 207-16. PMID 1306120 |
0.033 |
|
| 1992 |
Overby L, Nishio SJ, Lawton MP, Plopper CG, Philpot RM. Cellular localization of flavin-containing monooxygenase in rabbit lung. Experimental Lung Research. 18: 131-44. PMID 1572320 DOI: 10.3109/01902149209020656 |
0.032 |
|
| 1987 |
Tynes RE, Philpot RM. Tissue- and species-dependent expression of multiple forms of mammalian microsomal flavin-containing monooxygenase. Molecular Pharmacology. 31: 569-74. PMID 3600601 |
0.032 |
|
| 1999 |
Ripp SL, Itagaki K, Philpot RM, Elfarra AA. Species and sex differences in expression of flavin-containing monooxygenase form 3 in liver and kidney microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 27: 46-52. PMID 9884308 |
0.031 |
|
| 1990 |
McDowell EM, Zhang XM, Philpot RM, De Santi AM, Strum JM. Immunohistochemical demonstration of cytochrome P-450 monooxygenase in regenerating tracheal epithelium: a recapitulation of fetal development. Virchows Archiv. B, Cell Pathology Including Molecular Pathology. 59: 243-9. PMID 1980174 DOI: 10.1007/BF02899410 |
0.031 |
|
| 1982 |
Serabjit-Singh CJ, Albro PW, Philpot RM. The effect of Aroclor 1260 on rabbit pulmonary cytochrome p-450 isozymes Federation Proceedings. 41: No. 7070. |
0.031 |
|
| 1991 |
Kim SG, Philpot RM, Novak RF. Pyridine effects on P450IIE1, IIB and IVB expression in rabbit liver: characterization of high- and low-affinity pyridine N-oxygenases. The Journal of Pharmacology and Experimental Therapeutics. 259: 470-7. PMID 1920133 |
0.031 |
|
| 1985 |
Garst JE, Wilson WC, Kristensen NC, Harrison PC, Corbin JE, Simon J, Philpot RM, Szabo RR. Species susceptibility to the pulmonary toxicity of 3-furyl isoamyl ketone (perilla ketone): in vivo support for involvement of the lung monooxygenase system. Journal of Animal Science. 60: 248-57. PMID 3972746 |
0.031 |
|
| 1978 |
Patel JM, Wolf CR, Philpot RM. The destruction of rabbit pulmonary cytochrome P-450 associated with the metabolism of p-xylene Federation Proceedings. 37: No. 2903. |
0.031 |
|
| 1981 |
Slaughter SR, Philpot RM, Statman CN, Boyd MR. Covalent binding of metabolically activated 4-ipomeanol to rabbit pulmonary and hepatic microsomal proteins Federation Proceedings. 40: 577. |
0.031 |
|
| 1994 |
Overby LH, Gardlik S, Philpot RM, Serabjit-Singh CJ. Unique distribution profiles of glutathione S-transferases in regions of kidney, ureter, and bladder of rabbit. Laboratory Investigation; a Journal of Technical Methods and Pathology. 70: 468-78. PMID 8176887 |
0.03 |
|
| 1994 |
Burnett VL, Lawton MP, Philpot RM. Cloning and sequencing of flavin-containing monooxygenases FMO3 and FMO4 from rabbit and characterization of FMO3. The Journal of Biological Chemistry. 269: 14314-22. PMID 8188717 |
0.03 |
|
| 1981 |
Devereux TR, Serabjit-Singh CJ, Slaughter SR, Wolf CR, Philpot RM, Fouts JR. Identification of cytochrome P-450 isozymes in nonciliated bronchiolar epithelial (Clara) and alveolar type II cells isolated from rabbit lung. Experimental Lung Research. 2: 221-30. PMID 7028473 DOI: 10.3109/01902148109052317 |
0.03 |
|
| 1994 |
Lawton MP, Cashman JR, Cresteil T, Dolphin CT, Elfarra AA, Hines RN, Hodgson E, Kimura T, Ozols J, Phillips IR, Philpot RM, Poulsen LL, Rettie AE, Shephard EA, Williams DE, et al. A Nomenclature for the Mammalian Flavin-Containing Monooxygenase Gene Family Based on Amino Acid Sequence Identities Archives of Biochemistry and Biophysics. 308: 254-257. PMID 8311461 DOI: 10.1006/Abbi.1994.1035 |
0.03 |
|
| 1987 |
Vanderslice RR, Domin BA, Carver GT, Philpot RM. Species-dependent expression and induction of homologues of rabbit cytochrome P-450 isozyme 5 in liver and lung. Molecular Pharmacology. 31: 320-5. PMID 3574284 |
0.03 |
|
| 1988 |
Serabjit-Singh CJ, Nishio SJ, Philpot RM, Plopper CG. The distribution of cytochrome P-450 monooxygenase in cells of the rabbit lung: an ultrastructural immunocytochemical characterization. Molecular Pharmacology. 33: 279-89. PMID 3352593 |
0.029 |
|
| 1978 |
Smith BR, Philpot RM, Bend JR. Metabolism of benzo[a]pyrene by the isolated perfused rabbit lung Drug Metabolism and Disposition. 6: 425-431. PMID 28923 |
0.029 |
|
| 1991 |
Gardlik S, Gasser R, Philpot RM, Serabjit-Singh CJ. The major alpha-class glutathione S-transferases of rabbit lung and liver. Primary sequences, expression, and regulation. The Journal of Biological Chemistry. 266: 19681-7. PMID 1918075 |
0.029 |
|
| 1979 |
Kalyanaraman B, Mason RP, Perez-Reyes E, Chignell CF, Wolf CR, Philpot RM. Characterization of the free radical formed in aerobic microsomal incubations containing carbon tetrachloride and NADPH. Biochemical and Biophysical Research Communications. 89: 1065-72. PMID 40551 DOI: 10.1016/0006-291X(79)92116-8 |
0.029 |
|
| 1986 |
Domin BA, Devereux TR, Philpot RM. The cytochrome P-450 monooxygenase system of rabbit lung enzyme components, activities, and induction in the nonciliated bronchiolar epithelial (Clara) cell, alveolar type II cell, and alveolar macrophage. Molecular Pharmacology. 30: 296-303. PMID 3092027 |
0.028 |
|
| 1993 |
Philpot RM. Modulation of the pulmonary cytochrome P450 system as a factor in pulmonary-selective toxic responses: fact and fiction. American Journal of Respiratory Cell and Molecular Biology. 9: 347-9. PMID 8398173 |
0.028 |
|
| 1977 |
Devereux TR, Philpot RM, Fouts JR. The effect of Hg2+ on rabbit hepatic and pulmonary solubilized, partially purified N,N-dimethylaniline N-oxidases Chemico-Biological Interactions. 18: 277-287. PMID 912812 DOI: 10.1016/0009-2797(77)90014-X |
0.028 |
|
| 1997 |
Overby LH, Carver GC, Philpot RM. Quantitation and kinetic properties of hepatic microsomal and recombinant flavin-containing monooxygenases 3 and 5 from humans. Chemico-Biological Interactions. 106: 29-45. PMID 9305407 DOI: 10.1016/S0009-2797(97)00055-0 |
0.027 |
|
| 1976 |
Arinc E, Philpot RM. Preparation and properties of partially purified pulmonary cytochrome P 450 from rabbits Journal of Biological Chemistry. 251: 3213-3220. PMID 931984 |
0.027 |
|
| 1975 |
Philpot RM, Arinc E, Fouts JR. Separation and partial purification of two forms of hepatic cytochrome P 450 from untreated rabbits Pharmacologist. 17: No. 165. |
0.027 |
|
| 1982 |
Smith BR, Plummer JL, Wolf CR, Philpot RM, Bend JR. p-Xylene metabolism by rabbit lung and liver and its relationship to the selective destruction of pulmonary cytochrome P-450. The Journal of Pharmacology and Experimental Therapeutics. 223: 736-42. PMID 7143236 |
0.027 |
|
| 1980 |
Wolf CR, Kalyanaraman B, Mason RP, Philpot RM. The conversion of aromatic aldehydes to radical intermediates by cytochrome Federation Proceedings. 39: 3928. |
0.026 |
|
| 1990 |
Ferris NP, Philpot RM, Oxtoby JM, Armstrong RM. Freeze-drying foot-and-mouth disease virus antigens. I. Infectivity studies. Journal of Virological Methods. 29: 43-52. PMID 1698805 DOI: 10.1016/0166-0934(90)90006-2 |
0.026 |
|
| 2009 |
Philpot R. A patient's duty to follow up. Australian Family Physician. 38: 859. PMID 19899196 |
0.026 |
|
| 1990 |
Schulze J, Richter E, Philpot RM. Tissue, species, and substrate concentration differences in the position-selective hydroxylation of N-nitrosodibutylamine. Relationship to the distribution of cytochrome P-450 isozymes 2 (IIB) and 5 (IVB). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 18: 398-402. PMID 1976059 |
0.025 |
|
| 1986 |
Harris C, Philpot RM, Hernandez O, Bend JR. Rabbit pulmonary cytochrome P-450 monooxygenase system: isozyme differences in the rate and stereoselectivity of styrene oxidation. The Journal of Pharmacology and Experimental Therapeutics. 236: 144-9. PMID 3941390 |
0.025 |
|
| 1980 |
Harrelson WG, Wolf CR, Philpot RM. Carbon tetrachloride-induced cofactor depletion in hepatic microsomes Federation Proceedings. 39: 3155. |
0.023 |
|
| 1975 |
Arinc E, Philpot RM. Partial purification and properties of pulmonary cytochrome P 450 from untreated rabbits Pharmacologist. 17: No.58. |
0.023 |
|
| 1989 |
Devereux TR, Domin BA, Philpot RM. Xenobiotic metabolism by isolated pulmonary cells. Pharmacology & Therapeutics. 41: 243-56. PMID 2652151 DOI: 10.1016/0163-7258(89)90109-5 |
0.022 |
|
| 1974 |
Philpot RM. Spectral analysis of a solubilized hepatic cytochrome P 450 preparation for determination of contamination by cytochrome b5 and unreactive cytochrome P 450 Chemico-Biological Interactions. 9: 169-180. PMID 4426106 |
0.022 |
|
| 1976 |
Philpot RM, Arinc E. Separation and purification of two forms of hepatic cytochrome P 450 from untreated rabbits Molecular Pharmacology. 12: 483-493. PMID 934060 |
0.022 |
|
| 1993 |
Atta-Asafo-Adjei E, Lawton MP, Philpot RM. Cloning, sequencing, distribution, and expression in Escherichia coli of flavin-containing monooxygenase 1C1. Evidence for a third gene subfamily in rabbits. The Journal of Biological Chemistry. 268: 9681-9. PMID 8486656 |
0.022 |
|
| 1981 |
Slaughter SR, Wolf CR, Marciniszyn JP, Philpot RM. The rabbit pulmonary monooxygenase system. partial structural characterization of the cytochrome P-450 components and comparison to the hepatic cytochrome P-450 Journal of Biological Chemistry. 256: 2499-2503. PMID 7462252 |
0.022 |
|
| 1991 |
Lawton MP, Kronbach T, Johnson EF, Philpot RM. Properties of expressed and native flavin-containing monooxygenases: evidence of multiple forms in rabbit liver and lung. Molecular Pharmacology. 40: 692-8. PMID 1944240 |
0.022 |
|
| 1995 |
Smith PB, Tiano HF, Nesnow S, Boyd MR, Philpot RM, Langenbach R. 4-Ipomeanol and 2-aminoanthracene cytotoxicity in C3H/10T1/2 cells expressing rabbit cytochrome P450 4B1. Biochemical Pharmacology. 50: 1567-75. PMID 7503758 DOI: 10.1016/0006-2952(95)02029-2 |
0.02 |
|
| 1988 |
Sabourin PJ, Tynes RE, Philpot RM, Winquist S, Dahl AR. Distribution of microsomal monooxygenases in the rabbit respiratory tract. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 16: 557-62. PMID 2903023 |
0.02 |
|
| 1975 |
Philpot RM, Arinc E, Fouts JR. Reconstitution of the rabbit pulmonary microsomal mixed function oxidase system from solubilized components Drug Metabolism and Disposition. 3: 118-126. PMID 236158 |
0.02 |
|
| 1990 |
Gasser R, Tynes RE, Lawton MP, Korsmeyer KK, Ziegler DM, Philpot RM. The flavin-containing monooxygenase expressed in pig liver: primary sequence, distribution, and evidence for a single gene. Biochemistry. 29: 119-24. PMID 2322534 DOI: 10.1021/bi00453a014 |
0.019 |
|
| 1996 |
Wyatt MK, Philpot RM, Carver G, Lawton MP, Nikbakht KN. Structural characteristics of flavin-containing monooxygenase genes one and two (FMO1 and FMO2). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 24: 1320-7. PMID 8971137 |
0.019 |
|
| 1985 |
Bend JR, Serabjit-Singh CJ, Philpot RM. The pulmonary uptake, accumulation, and metabolism of xenobiotics. Annual Review of Pharmacology and Toxicology. 25: 97-125. PMID 3890717 DOI: 10.1146/annurev.pa.25.040185.000525 |
0.018 |
|
| 2011 |
Philpot R. Monoamine vesicular transporters Xpharm: the Comprehensive Pharmacology Reference. 1-1. DOI: 10.1016/B978-008055232-3.63800-0 |
0.017 |
|
| 1991 |
Philpot RM. Characterization of cytochrome P450 in extrahepatic tissues. Methods in Enzymology. 206: 623-31. PMID 1784245 |
0.017 |
|
| 1980 |
Wolf CR, Harrelson WG, Nastainczyk WM, Philpot RM, Kalyanaraman B, Mason RP. Metabolism of carbon tetrachloride in hepatic microsomes and reconstituted monooxygenase systems and its relationship to lipid peroxidation Molecular Pharmacology. 18: 553-558. PMID 7464817 |
0.017 |
|
| 1994 |
Grimm SW, Dyroff MC, Philpot RM, Halpert JR. Catalytic selectivity and mechanism-based inactivation of stably expressed and hepatic cytochromes P450 2B4 and 2B5: implications of the cytochrome P450 2B5 polymorphism. Molecular Pharmacology. 46: 1090-9. PMID 7808429 |
0.017 |
|
| 2007 |
Philpot R. The role of host-pathogen interactions in chronic obstructive pulmonary disease exacerbations is unclear. Internal Medicine Journal. 37: 840; author reply 80. PMID 18028094 DOI: 10.1111/j.1445-5994.2007.01549.x |
0.017 |
|
| 1988 |
Gasser R, Negishi M, Philpot RM. Primary structures of multiple forms of cytochrome P-450 isozyme 2 derived from rabbit pulmonary and hepatic cDNAs. Molecular Pharmacology. 33: 22-30. PMID 2826996 |
0.016 |
|
| 2004 |
Philpot R. Highly active antiretroviral therapy: a misnomer in HIV/AIDS terminology. Internal Medicine Journal. 34: 139. PMID 15030469 DOI: 10.1111/j.1444-0903.2004.00557.x |
0.015 |
|
| 1995 |
Fisher MB, Lawton MP, Atta-Asafo-Adjei E, Philpot RM, Rettie AE. Selectivity of flavin-containing monooxygenase 5 for the (S)-sulfoxidation of short-chain aralkyl sulfides. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 23: 1431-3. PMID 8689956 |
0.015 |
|
| 1985 |
Serabjit-Singh CJ, Bend JR, Philpot RM. Cytochrome P-450 monooxygenase system. Localization in smooth muscle of rabbit aorta. Molecular Pharmacology. 28: 72-9. PMID 3927149 |
0.015 |
|
| 1975 |
Hodgson E, Philpot RM. Interaction of methylenedioxyphenyl (1,3-benzodioxole) compounds with enzymes and their effects on mammals Drug Metabolism Reviews. 3: 231-301. PMID 4423562 DOI: 10.3109/03602537408993744 |
0.012 |
|
| 1997 |
Ripp SL, Overby LH, Philpot RM, Elfarra AA. Oxidation of cysteine S-conjugates by rabbit liver microsomes and cDNA-expressed flavin-containing mono-oxygenases: studies with S-(1,2-dichlorovinyl)-L-cysteine, S-(1,2,2-trichlorovinyl)-L-cysteine, S-allyl-L-cysteine, and S-benzyl-L-cysteine. Molecular Pharmacology. 51: 507-15. PMID 9058607 |
0.012 |
|
| 1980 |
Wolf CR, Slaughter SR, Marciniszyn JP, Philpot RM. Purification and structural comparison of pulmonary and hepatic cytochrome P-450 from rabbits Biochimica Et Biophysica Acta. 624: 409-419. PMID 7417485 |
0.011 |
|
| 1980 |
Croft JE, Wolf CR, Holland JF, Philpot RM. The role of cytochrome b5 in the O-demethylation of p-nitroanisole Federation Proceedings. 39: 3144. |
0.011 |
|
| 1998 |
Antal GM, Philpot R. Letters to the Editors Venereology. 11: 42-43. |
0.01 |
|
| 2011 |
Philpot R. Vecuronium Xpharm: the Comprehensive Pharmacology Reference. 1-1. DOI: 10.1016/B978-008055232-3.63950-9 |
0.01 |
|
| 2011 |
Philpot R. Aussie rules Ebr - European Biopharmaceutical Review. 94-96. |
0.01 |
|
| 2006 |
Philpot R. Cooperation between GPs and psychiatrists. Australian Family Physician. 35: 377. PMID 16783901 |
0.01 |
|
| 2003 |
Philpot R. General internal medicine in Australasia. Internal Medicine Journal. 33: 136. PMID 12603591 DOI: 10.1046/j.1445-5994.2003.00370.x |
0.01 |
|
| 2002 |
Philpot R. Insulins in 2002 [1] Australian Prescriber. 25: 104. |
0.01 |
|
| 1993 |
Lawton MP, Philpot RM. Functional characterization of flavin-containing monooxygenase 1B1 expressed in Saccharomyces cerevisiae and Escherichia coli and analysis of proposed FAD- and membrane-binding domains. The Journal of Biological Chemistry. 268: 5728-34. PMID 8449936 |
0.01 |
|
| 1988 |
Harcourt C, Edwards J, Philpot R. On the "Grim Reaper" campaign. The Medical Journal of Australia. 149: 162, 164. PMID 3398804 |
0.01 |
|
| 1981 |
Croft JE, Harrelson WG, Philpot RM. NADPH and NADH O-demethylation of p-nitroanisole Pharmacologist. 23: No. 293. |
0.01 |
|
| 1979 |
Serabjit-Singh CJ, Wolf CR, Philpot RM. The rabbit pulmonary monooxygenase system; Immunochemical and biochemical characterization of enzyme components Journal of Biological Chemistry. 254: 9901-9907. PMID 114516 |
0.01 |
|
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