Kristoffer Myczek, Ph.D. - Related publications

Neurobiology & Behavior University of California, Irvine, Irvine, CA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Guyot AC, Leuxe C, Disdier C, Oumata N, Costa N, Roux GL, Fernandez-Varela P, Duchon A, Charbonnier JB, Herault Y, Pavoni S, Galons H, Andriambeloson E, Wagner S, Meijer L, et al. A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment. Scientific Reports. 10: 1143. PMID 31980673 DOI: 10.1038/s41598-020-57560-3   
2020 Iyaswamy A, Krishnamoorthi SK, Song JX, Yang CB, Kaliyamoorthy V, Zhang H, Sreenivasmurthy SG, Malampati S, Wang ZY, Zhu Z, Tong BC, Cheung KH, Lu JH, Durairajan SSK, Li M. NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models. Journal of Food and Drug Analysis. 28: 132-146. PMID 31883601 DOI: 10.1016/j.jfda.2019.09.004   
2020 Birla H, Minocha T, Kumar G, Misra A, Singh SK. Role Of Oxidative Stress And Metal Toxicity In The Progression Of Alzheimer's Disease. Current Neuropharmacology. PMID 31969104 DOI: 10.2174/1570159X18666200122122512   
2020 Polis B, Samson AO. Role of the metabolism of branched-chain amino acids in the development of Alzheimer's disease and other metabolic disorders. Neural Regeneration Research. 15: 1460-1470. PMID 31997805 DOI: 10.4103/1673-5374.274328   
2020 Evans CE, Miners JS, Piva G, Willis CL, Heard DM, Kidd EJ, Good MA, Kehoe PG. ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease. Acta Neuropathologica. PMID 31982938 DOI: 10.1007/s00401-019-02098-6   
2020 Zhu Q, Zhang N, Hu N, Jiang R, Lu H, Xuan A, Long D, Chen Y. Neural stem cell transplantation improves learning and memory by protecting cholinergic neurons and restoring synaptic impairment in an amyloid precursor protein/presenilin 1 transgenic mouse model of Alzheimer's disease. Molecular Medicine Reports. PMID 31922229 DOI: 10.3892/mmr.2020.10918   
2020 Kim H, Kim B, Kim HS, Cho JY. Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer's disease animal model. Molecular Brain. 13: 17. PMID 32033569 DOI: 10.1186/s13041-020-0565-x   
2020 Chen C, Xu D, Zhang ZH, Jia SZ, Cao XC, Chen YB, Song GL, Wong MS, Li HW. Cognitive improvement and synaptic deficit attenuation by a multifunctional carbazole-based cyanine in AD mice model through regulation of Ca/CaMKII/CREB signaling pathway. Experimental Neurology. 113210. PMID 31987831 DOI: 10.1016/j.expneurol.2020.113210   
2020 Nuñez-Borque E, González-Naranjo P, Bartolomé F, Alquézar C, Reinares-Sebastián A, Pérez C, Ceballos ML, Páez JA, Campillo NE, Martín-Requero Á. Targeting Cannabinoid Receptor Activation and BACE-1 Activity Counteracts TgAPP Mice Memory Impairment and Alzheimer's Disease Lymphoblast Alterations. Molecular Neurobiology. PMID 31898159 DOI: 10.1007/s12035-019-01813-4   
2020 Calvo-Flores Guzmán B, Kim S, Chawdhary B, Peppercorn K, Tate WP, Waldvogel HJ, Faull RL, Montgomery J, Kwakowsky A. Amyloid-Beta -Induced Increase in GABAergic Tonic Conductance in Mouse Hippocampal CA1 Pyramidal Cells. Molecules (Basel, Switzerland). 25. PMID 32041202 DOI: 10.3390/molecules25030693   
2020 Zhang W, Luo P. Myocardial Infarction Predisposes Neurodegenerative Diseases. Journal of Alzheimer's Disease : Jad. PMID 32065796 DOI: 10.3233/JAD-191225   
2020 Ricke KM, Cruz SA, Qin Z, Farrokhi K, Sharmin F, Zhang L, Zasloff MA, Stewart AFR, Chen HH. Neuronal Protein Tyrosine Phosphatase 1B hastens Amyloid β-associated Alzheimer's disease in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31915254 DOI: 10.1523/JNEUROSCI.2120-19.2019   
2020 Uddin MS, Kabir MT, Tewari D, Mathew B, Aleya L. Emerging signal regulating potential of small molecule biflavonoids to combat neuropathological insults of Alzheimer's disease. The Science of the Total Environment. 700: 134836. PMID 31704512 DOI: 10.1016/j.scitotenv.2019.134836   
2020 Gray SC, Kinghorn KJ, Woodling NS. Shifting equilibriums in Alzheimer's disease: the complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis. Neural Regeneration Research. 15: 1208-1219. PMID 31960800 DOI: 10.4103/1673-5374.272571   
2020 Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, Waragai M, Ohtomo G, Iwata A, Tagawa K, Atsuta N, Katsuno M, Tomita N, Furukawa K, Saito Y, et al. YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. Nature Communications. 11: 507. PMID 31980612 DOI: 10.1038/s41467-020-14353-6   
2020 Yan T, Liang J, Gao J, Wang L, Fujioka H, , Zhu X, Wang X. FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease. Nature Communications. 11: 411. PMID 31964863 DOI: 10.1038/s41467-019-13962-0   
2020 Raman S, Brookhouser N, Brafman DA. Using human induced pluripotent stem cells (hiPSCs) to investigate the mechanisms by which Apolipoprotein E (APOE) contributes to Alzheimer's disease (AD) risk. Neurobiology of Disease. 104788. PMID 32032733 DOI: 10.1016/j.nbd.2020.104788   
2020 Chandler HL, Hodgetts CJ, Caseras X, Murphy K, Lancaster TM. Polygenic risk for Alzheimer's disease shapes hippocampal scene-selectivity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31896120 DOI: 10.1038/s41386-019-0595-1   
2020 Dong Y, Stewart T, Bai L, Li X, Xu T, Iliff J, Shi M, Zheng D, Yuan L, Wei T, Yang X, Zhang J. Coniferaldehyde attenuates Alzheimer's pathology activation of Nrf2 and its targets. Theranostics. 10: 179-200. PMID 31903114 DOI: 10.7150/thno.36722   
2020 Dawe RJ, Yu L, Arfanakis K, Schneider JA, Bennett DA, Boyle PA. Late-life cognitive decline is associated with hippocampal volume, above and beyond its associations with traditional neuropathologic indices. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 209-218. PMID 31914231 DOI: 10.1002/alz.12009   
2020 Cannavo C, Tosh J, Fisher EMC, Wiseman FK. Using mouse models to understand Alzheimer's disease mechanisms in the context of trisomy of chromosome 21. Progress in Brain Research. 251: 181-208. PMID 32057307 DOI: 10.1016/bs.pbr.2019.10.004   
2020 Weigand AJ, Bangen KJ, Thomas KR, Delano-Wood L, Gilbert PE, Brickman AM, Bondi MW, . Is tau in the absence of amyloid on the Alzheimer's continuum?: A study of discordant PET positivity. Brain Communications. 2: fcz046. PMID 32051933 DOI: 10.1093/braincomms/fcz046   
2020 Hou TT, Han YD, Cong L, Liu CC, Liang XY, Xue FZ, Du YF. Apolipoprotein E Facilitates Amyloid-β Oligomer-Induced Tau Phosphorylation. Journal of Alzheimer's Disease : Jad. PMID 32065788 DOI: 10.3233/JAD-190711   
2020 Jeon Y, Lee JH, Choi B, Won SY, Cho KS. Genetic Dissection of Alzheimer's Disease Using Models. International Journal of Molecular Sciences. 21. PMID 32019113 DOI: 10.3390/ijms21030884   
2020 Du Y, Fu M, Huang Z, Tian X, Li J, Pang Y, Song W, Tian Wang Y, Dong Z. TRPV1 activation alleviates cognitive and synaptic plasticity impairments through inhibiting AMPAR endocytosis in APP23/PS45 mouse model of Alzheimer's disease. Aging Cell. e13113. PMID 32061032 DOI: 10.1111/acel.13113   
2020 Arenaza-Urquijo EM, Przybelski SA, Machulda MM, Knopman DS, Lowe VJ, Mielke MM, Reddy AL, Geda YE, Jack CR, Petersen RC, Vemuri P. Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults. Neurology. PMID 31964689 DOI: 10.1212/WNL.0000000000008979   
2020 Robison LS, Francis N, Popescu DL, Anderson ME, Hatfield J, Xu F, Anderson BJ, Van Nostrand WE, Robinson JK. Environmental Enrichment: Disentangling the Influence of Novelty, Social, and Physical Activity on Cerebral Amyloid Angiopathy in a Transgenic Mouse Model. International Journal of Molecular Sciences. 21. PMID 32012921 DOI: 10.3390/ijms21030843   
2020 Svensson M, Andersson E, Manouchehrian O, Yang Y, Deierborg T. Voluntary running does not reduce neuroinflammation or improve non-cognitive behavior in the 5xFAD mouse model of Alzheimer's disease. Scientific Reports. 10: 1346. PMID 31992814 DOI: 10.1038/s41598-020-58309-8   
2020 Li X, Wang L, Cykowski M, He T, Liu T, Chakranarayan J, Rivera A, Zhao H, Powell S, Xia W, Wong STC. OCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages. Ebiomedicine. 51: 102569. PMID 31931285 DOI: 10.1016/j.ebiom.2019.11.030   
2020 Prikhodko O, Rynearson KD, Sekhon T, Mante MM, Nguyen PD, Rissman RA, Tanzi RE, Wagner SL. The GSM BPN-15606 as a Potential Candidate for Preventative Therapy in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31958080 DOI: 10.3233/JAD-190442   
2020 Schrank S, McDaid J, Briggs CA, Mustaly-Kalimi S, Brinks D, Houcek A, Singer O, Bottero V, Marr RA, Stutzmann GE. Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer's Disease Pathology. International Journal of Molecular Sciences. 21. PMID 32033164 DOI: 10.3390/ijms21031030   
2020 Malampati S, Song JX, Chun-Kit Tong B, Nalluri A, Yang CB, Wang Z, Gopalkrishnashetty Sreenivasmurthy S, Zhu Z, Liu J, Su C, Krishnamoorthi S, Iyaswamy A, Cheung KH, Lu JH, Li AM. Targeting Aggrephagy for the Treatment of Alzheimer's Disease. Cells. 9. PMID 32012902 DOI: 10.3390/cells9020311   
2020 Chintapaludi SR, Uyar A, Jackson HM, Acklin CJ, Wang X, Sasner M, Carter GW, Howell GR. Staging Alzheimer's Disease in the Brain and Retina of B6.APP/PS1 Mice by Transcriptional Profiling. Journal of Alzheimer's Disease : Jad. PMID 31929156 DOI: 10.3233/JAD-190793   
2020 Li J, Zhao R, Jiang Y, Xu Y, Zhao H, Lyu X, Wu T. Bilberry anthocyanins improve neuroinflammation and cognitive dysfunction in APP/PSEN1 mice via the CD33/TREM2/TYROBP signaling pathway in microglia. Food & Function. PMID 32003387 DOI: 10.1039/c9fo02103e   
2020 Gomez W, Morales R, Maracaja-Coutinho V, Parra V, Nassif M. Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein. Aging. 11. PMID 31918411 DOI: 10.18632/aging.102677   
2020 Zhou H, Gong Y, Liu Y, Huang A, Zhu X, Liu J, Yuan G, Zhang L, Wei JA, Liu J. Intelligently thermoresponsive flower-like hollow nano-ruthenium system for sustained release of nerve growth factor to inhibit hyperphosphorylation of tau and neuronal damage for the treatment of Alzheimer's disease. Biomaterials. 237: 119822. PMID 32035322 DOI: 10.1016/j.biomaterials.2020.119822   
2020 Fernando WMADB, Martins IJ, Morici M, Bharadwaj P, Rainey-Smith SR, Lim WLF, Martins RN. Sodium Butyrate Reduces Brain Amyloid-β Levels and Improves Cognitive Memory Performance in an Alzheimer's Disease Transgenic Mouse Model at an Early Disease Stage. Journal of Alzheimer's Disease : Jad. PMID 31958090 DOI: 10.3233/JAD-190120   
2020 Fernando WMADB, Martins IJ, Morici M, Bharadwaj P, Rainey-Smith SR, Lim WLF, Martins RN. Sodium Butyrate Reduces Brain Amyloid-β Levels and Improves Cognitive Memory Performance in an Alzheimer's Disease Transgenic Mouse Model at an Early Disease Stage. Journal of Alzheimer's Disease : Jad. PMID 31958090 DOI: 10.3233/JAD-190120   
2020 Singh RK. Recent trends in management of Alzheimer's disease: Current therapeutic options and drug repurposing approaches. Current Neuropharmacology. PMID 31989900 DOI: 10.2174/1570159X18666200128121920   
2020 Lin C, Ly M, Karim HT, Wei W, Snitz BE, Klunk WE, Aizenstein HJ. The effect of amyloid deposition on longitudinal resting-state functional connectivity in cognitively normal older adults. Alzheimer's Research & Therapy. 12: 7. PMID 31907079 DOI: 10.1186/s13195-019-0573-1   
2020 Zhao N, Attrebi ON, Ren Y, Qiao W, Sonustun B, Martens YA, Meneses AD, Li F, Shue F, Zheng J, Van Ingelgom AJ, Davis MD, Kurti A, Knight JA, Linares C, et al. APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid. Science Translational Medicine. 12. PMID 32024798 DOI: 10.1126/scitranslmed.aay1809   
2020 Williams T, Borchelt DR, Chakrabarty P. Therapeutic approaches targeting Apolipoprotein E function in Alzheimer's disease. Molecular Neurodegeneration. 15: 8. PMID 32005122 DOI: 10.1186/s13024-020-0358-9   
2020 Whitwell JL, Tosakulwong N, Weigand SD, Graff-Radford J, Duffy JR, Clark HM, Machulda MM, Botha H, Utianski RL, Schwarz CG, Senjem ML, Strand EA, Ertekin-Taner N, Jack CR, Lowe VJ, et al. Longitudinal Amyloid-β PET in Atypical Alzheimer's Disease and Frontotemporal Lobar Degeneration. Journal of Alzheimer's Disease : Jad. PMID 32039841 DOI: 10.3233/JAD-190699   
2020 Alber J, Goldfarb D, Thompson LI, Arthur E, Hernandez K, Cheng D, DeBuc DC, Cordeiro F, Provetti-Cunha L, den Haan J, Van Stavern GP, Salloway SP, Sinoff S, Snyder PJ. Developing retinal biomarkers for the earliest stages of Alzheimer's disease: What we know, what we don't, and how to move forward. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 229-243. PMID 31914225 DOI: 10.1002/alz.12006   
2020 Wisniewski T, Drummond E. APOE-amyloid interaction: Therapeutic targets. Neurobiology of Disease. 104784. PMID 32027932 DOI: 10.1016/j.nbd.2020.104784   
2020 Hashiguchi D, Campos HC, Wuo-Silva R, Faber J, Gomes da Silva S, Coppi AA, Arida RM, Longo BM. Resistance Exercise Decreases Amyloid Load and Modulates Inflammatory Responses in the APP/PS1 Mouse Model for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31958083 DOI: 10.3233/JAD-190729   
2020 Zhong S, Wang M, Zhan Y, Zhang J, Yang X, Fu S, Bi D, Gao F, Shen Y, Chen Z. Single-nucleus RNA sequencing reveals transcriptional changes of hippocampal neurons in APP23 mouse model of Alzheimer's disease. Bioscience, Biotechnology, and Biochemistry. 1-8. PMID 31928331 DOI: 10.1080/09168451.2020.1714420   
2020 Streit WJ, Khoshbouei H, Bechmann I. Dystrophic microglia in late-onset Alzheimer's disease. Glia. PMID 31922322 DOI: 10.1002/glia.23782   
2020 Yang P, Sheng D, Guo Q, Wang P, Xu S, Qian K, Li Y, Cheng Y, Wang L, Lu W, Zhang Q. Neuronal mitochondria-targeted micelles relieving oxidative stress for delayed progression of Alzheimer's disease. Biomaterials. 238: 119844. PMID 32062148 DOI: 10.1016/j.biomaterials.2020.119844   
2020 Pereira JB, Harrison TM, La Joie R, Baker SL, Jagust WJ. Spatial patterns of tau deposition are associated with amyloid, ApoE, sex, and cognitive decline in older adults. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31915896 DOI: 10.1007/s00259-019-04669-x