Luis Miguel GARCIA-SEGURA, PhD - Related publications

CSIC Cajal Institute, Madrid, Spain 
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Han ZW, Zhu LC, Chang YC, Zhou Y, Zong JA, Ma KT, Si JQ, Li L. [G protein-coupled estrogen receptor alleviates cerebral ischemia-reperfusion injury through inhibiting endoplasmic reticulum stress]. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 71: 527-536. PMID 31440749   
2019 Chen Y, Tian Y, Tian H, Huang Q, Fang Y, Wang W, Wan Y, Pan D, Xie M. Tamoxifen promotes white matter recovery and cognitive functions in male mice after chronic hypoperfusion. Neurochemistry International. 104566. PMID 31593788 DOI: 10.1016/j.neuint.2019.104566   
2019 Sun N, Chu L, Yuan L, Qi Z. Inactivation of P2YR12 contributes to isoflurane-induced neuronal injury by altering TLR-4/BDNF/TNF-α. Folia Neuropathologica. 57: 161-169. PMID 31556575 DOI: 10.5114/fn.2019.86295   
2019 Zhao R, Zhao K, Su H, Zhang P, Zhao N. Resveratrol ameliorates brain injury via the TGF-β-mediated ERK signaling pathway in a rat model of cerebral hemorrhage. Experimental and Therapeutic Medicine. 18: 3397-3404. PMID 31602214 DOI: 10.3892/etm.2019.7939   
2019 Kapoor M, Sharma S, Sandhir R, Nehru B. Temporal changes in physiological and molecular markers in various brain regions following transient global ischemia in rats. Molecular Biology Reports. PMID 31576510 DOI: 10.1007/s11033-019-05060-7   
2019 Tang Z, Cheng S, Sun Y, Zhang Y, Xiang X, Ouyang Z, Zhu X, Wang B, Hei M. Early TLR4 inhibition reduces hippocampal injury at puberty in a rat model of neonatal hypoxic-ischemic brain damage via regulation of neuroimmunity and synaptic plasticity. Experimental Neurology. 113039. PMID 31442443 DOI: 10.1016/j.expneurol.2019.113039   
2019 Tang Z, Cheng S, Sun Y, Zhang Y, Xiang X, Ouyang Z, Zhu X, Wang B, Hei M. Early TLR4 inhibition reduces hippocampal injury at puberty in a rat model of neonatal hypoxic-ischemic brain damage via regulation of neuroimmunity and synaptic plasticity. Experimental Neurology. 113039. PMID 31442443 DOI: 10.1016/j.expneurol.2019.113039   
2019 Zhu Y, Li S, Liu J, Wen Q, Yu J, Yu L, Xie K. Role of JNK Signaling Pathway in Dexmedetomidine Post-Conditioning-Induced Reduction of the Inflammatory Response and Autophagy Effect of Focal Cerebral Ischemia Reperfusion Injury in Rats. Inflammation. PMID 31446520 DOI: 10.1007/s10753-019-01082-2   
2019 Seydyousefi M, Moghanlou AE, Metz GAS, Gursoy R, Faghfoori MH, Mirghani SJ, Faghfoori Z. Exogenous adenosine facilitates neuroprotection and functional recovery following cerebral ischemia in rats. Brain Research Bulletin. 153: 250-256. PMID 31545998 DOI: 10.1016/j.brainresbull.2019.09.010   
2019 Yang X, Feng P, Zhang X, Li D, Wang R, Ji C, Li G, Hölscher C. The diabetes drug semaglutide reduces infarct size, inflammation, and apoptosis, and normalizes neurogenesis in a rat model of stroke. Neuropharmacology. 107748. PMID 31465784 DOI: 10.1016/j.neuropharm.2019.107748   
2019 Li H, Wu L, Wang D, Guo Y, Liu T, Pan Y. A protective effect of baicalin on cerebral ischemic rats is related to the improvement of serum progesterone level in serum. Neuroreport. 30: 1121-1128. PMID 31568208 DOI: 10.1097/WNR.0000000000001340   
2019 Lu LY, Liu Y, Gong YF, Zheng XY. A preliminary report: genistein attenuates cerebral ischemia injury in ovariectomized rats via regulation of the PI3K-Akt-mTOR pathway. General Physiology and Biophysics. 38: 389-397. PMID 31595881 DOI: 10.4149/gpb_2019024   
2019 Li Y, Liu L, Tian Y, Zhang J. Rapamycin improves sevoflurane‑induced cognitive dysfunction in aged rats by mediating autophagy through the TLR4/MyD88/NF‑κB signaling pathway. Molecular Medicine Reports. PMID 31432123 DOI: 10.3892/mmr.2019.10541   
2019 Zhou Y, Gao G, Li Z, Jiang L. Protective Effect of Mitogen- and Stress-Activated Protein Kinase on the Rats with Focal Ischemia-Reperfusion Injury. Inflammation. PMID 31529230 DOI: 10.1007/s10753-019-01080-4   
2019 Higashi Y, Aratake T, Shimizu S, Shimizu T, Saito M. [Brain zinc dyshomeostasis and glial cells in ischemic stroke]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 154: 138-142. PMID 31527364 DOI: 10.1254/fpj.154.138   
2019 Jarras H, Bourque M, Poirier AA, Morissette M, Coulombe K, Di Paolo T, Soulet D. Neuroprotection and immunomodulation of progesterone in the gut of a mouse model of Parkinson's disease. Journal of Neuroendocrinology. e12782. PMID 31430407 DOI: 10.1111/jne.12782   
2019 Xie W, Zhu T, Dong X, Nan F, Meng X, Zhou P, Sun G, Sun X. HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-κB signaling pathways. Biomolecules. 9. PMID 31547018 DOI: 10.3390/biom9100512   
2019 Zhu MY, Raza MU, Zhan Y, Fan Y. Norepinephrine upregulates the expression of tyrosine hydroxylase and protects dopaminegic neurons against 6-hydrodopamine toxicity. Neurochemistry International. 131: 104549. PMID 31539561 DOI: 10.1016/j.neuint.2019.104549   
2019 Ao LY, Li WT, Zhou L, Yan YY, Ye AQ, Liang BW, Shen WY, Zhu X, Li YM. Therapeutic effects of JLX-001 on ischemic stroke by inducing autophagy via AMPK-ULK1 signaling pathway in rats'. Brain Research Bulletin. PMID 31472184 DOI: 10.1016/j.brainresbull.2019.08.017   
2019 Lee EH, Kim SM, Kim CH, Pagire SH, Pagire HS, Chung HY, Ahn JH, Park CH. Dopamine neuron induction and the neuroprotective effects of thyroid hormone derivatives. Scientific Reports. 9: 13659. PMID 31541140 DOI: 10.1038/s41598-019-49876-6   
2019 Zhou L, Ao LY, Yan YY, Li WT, Ye AQ, Li CY, Shen WY, Liang BW, Xiong-Zhu, Li YM. JLX001 Ameliorates Ischemia/Reperfusion Injury by Reducing Neuronal Apoptosis Via Downregulating JNK Signaling Pathway. Neuroscience. PMID 31487541 DOI: 10.1016/j.neuroscience.2019.08.053   
2019 Tong D, Godale CM, Kadakia FK, Gu Z, Danzer CSK, Alghamdi A, Zhao P, Loepke AW, Danzer SC. Immature murine hippocampal neurones do not develop long-term structural changes after a single isoflurane exposure. British Journal of Anaesthesia. PMID 31570162 DOI: 10.1016/j.bja.2019.08.019   
2019 Serra FT, Carvalho AD, Araujo BHS, Torres LB, Cardoso FDS, Henrique JS, Placencia EVD, Lent R, Gomez-Pinilla F, Arida RM, Gomes da Silva S. Early exercise induces long-lasting morphological changes in cortical and hippocampal neurons throughout of a sedentary period of rats. Scientific Reports. 9: 13684. PMID 31548605 DOI: 10.1038/s41598-019-50218-9   
2019 Wang N, He J, Pan C, Wang J, Ma M, Shi X, Xu Z. Resveratrol Activates Autophagy via the AKT/mTOR Signaling Pathway to Improve Cognitive Dysfunction in Rats With Chronic Cerebral Hypoperfusion. Frontiers in Neuroscience. 13: 859. PMID 31481868 DOI: 10.3389/fnins.2019.00859   
2019 Yang GE, Tae HJ, Lee TK, Park YE, Cho JH, Kim DW, Park JH, Ahn JH, Ryoo S, Kim YM, Shin MC, Cho JH, Lee CH, Hwang IK, Jin H, et al. Risperidone Treatment after Transient Ischemia Induces Hypothermia and Provides Neuroprotection in the Gerbil Hippocampus by Decreasing Oxidative Stress. International Journal of Molecular Sciences. 20. PMID 31540405 DOI: 10.3390/ijms20184621   
2019 Hu YJ, Xia LJ, Yao B, Chen L, Cheng J, Xia YB. [Repairing effect of wheat-grain moxibustion on thin-type endometrium in rats]. Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion. 39: 963-9. PMID 31544385 DOI: 10.13703/j.0255-2930.2019.09.012   
2019 Baba N, Wang F, Iizuka M, Shen Y, Yamashita T, Takaishi K, Tsuru E, Matsushima S, Miyamura M, Fujieda M, Tsuda M, Sagara Y, Maeda N. Induction of regional chemokine expression in response to human umbilical cord blood cell infusion in the neonatal mouse ischemia-reperfusion brain injury model. Plos One. 14: e0221111. PMID 31483787 DOI: 10.1371/journal.pone.0221111   
2019 Gu M, He P, Lyu C, Liu X, Xu Y, Cheng S, Gu Y, Jia Y. Spinosin and 6'''‑Feruloylspinosin protect the heart against acute myocardial ischemia and reperfusion in rats. Molecular Medicine Reports. PMID 31545438 DOI: 10.3892/mmr.2019.10686   
2019 Tarczyluk-Wells MA, Salzlechner C, Najafi AR, Lim MJ, Smith D, Platt FM, Williams BP, Cooper JD. Combined Anti-inflammatory and Neuroprotective Treatments Have the Potential to Impact Disease Phenotypes in Mice. Frontiers in Neurology. 10: 963. PMID 31572287 DOI: 10.3389/fneur.2019.00963   
2019 Franco PN, Durrant LM, Carreon D, Haddad E, Vergara A, Cascavita C, Obenaus A, Pearce WJ. Prenatal Metyrapone Treatment Modulates Neonatal Cerebrovascular Structure, Function and Vulnerability to Mild Hypoxic-Ischemic Injury. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. PMID 31577477 DOI: 10.1152/ajpregu.00145.2019   
2019 Denstaedt SJ, Spencer-Segal JL, Newstead M, Laborc K, Zeng X, Standiford TJ, Singer BH. Persistent Neuroinflammation and Brain Specific Immune Priming in A Novel Survival Model of Murine Pneumosepsis. Shock (Augusta, Ga.). PMID 31415473 DOI: 10.1097/SHK.0000000000001435   
2019 Wang JA, Tong ML, Zhao B, Zhu G, Xi DH, Yang JP. Parthenolide ameliorates intracerebral hemorrhage-induced brain injury in rats. Phytotherapy Research : Ptr. PMID 31497910 DOI: 10.1002/ptr.6510   
2019 Ahn JH, Kim DW, Park JH, Lee TK, Lee HA, Won MH, Lee CH. Expression changes of CX3CL1 and CX3CR1 proteins in the hippocampal CA1 field of the gerbil following transient global cerebral ischemia. International Journal of Molecular Medicine. PMID 31524247 DOI: 10.3892/ijmm.2019.4273   
2019 Qu XY, Zhang YM, Tao LN, Gao H, Zhai JH, Sun JM, Song YQ, Zhang SX. XingNaoJing injections protect against cerebral ischemia/reperfusion injury and alleviate blood-brain barrier disruption in rats, through an underlying mechanism of NLRP3 inflammasomes suppression. Chinese Journal of Natural Medicines. 17: 498-505. PMID 31514981 DOI: 10.1016/S1875-5364(19)30071-8   
2019 Panda S, Sikdar M, Biswas S, Sharma R, Kar A. Allylpyrocatechol, isolated from betel leaf ameliorates thyrotoxicosis in rats by altering thyroid peroxidase and thyrotropin receptors. Scientific Reports. 9: 12276. PMID 31439949 DOI: 10.1038/s41598-019-48653-9   
2019 Kerp H, Engels K, Kramer F, Doycheva D, Sebastian Hönes G, Zwanziger D, Christian Moeller L, Heuer H, Führer D. Age effect on thyroid hormone brain response in male mice. Endocrine. PMID 31494803 DOI: 10.1007/s12020-019-02078-6   
2019 Houlton J, Abumaria N, Hinkley SFR, Clarkson AN. Therapeutic Potential of Neurotrophins for Repair After Brain Injury: A Helping Hand From Biomaterials. Frontiers in Neuroscience. 13: 790. PMID 31427916 DOI: 10.3389/fnins.2019.00790   
2019 Yu Y, Lang XY, Li XX, Gu RZ, Liu QS, Lan R, Qin XY. 2,3,5,4'-Tetrahydroxystilbene-2-O-β-d-glucoside attenuates MPP+/MPTP-induced neurotoxicity in vitro and in vivo by restoring the BDNF-TrkB and FGF2-Akt signaling axis and inhibition of apoptosis. Food & Function. PMID 31482900 DOI: 10.1039/c9fo01309a   
2019 Zhang Y, Zhang C, Li H, Hou J. The Presence of High Levels of Circulating Trimethylamine N-Oxide Exacerbates Central and Peripheral Inflammation and Inflammatory Hyperalgesia in Rats Following Carrageenan Injection. Inflammation. PMID 31489527 DOI: 10.1007/s10753-019-01090-2   
2019 Liu X, Wu C, Han D, Liu J, Liu H, Jiang Z. Partially Hydrolyzed Guar Gum Attenuates d-Galactose-Induced Oxidative Stress and Restores Gut Microbiota in Rats. International Journal of Molecular Sciences. 20. PMID 31574948 DOI: 10.3390/ijms20194861   
2019 Mallozzi C, Pepponi R, Visentin S, Chiodi V, Lombroso PJ, Bader M, Popoli P, Domenici MR. The activity of the STriatal-Enriched protein tyrosine Phosphatase (STEP) in neuronal cells is modulated by adenosine A receptor. Journal of Neurochemistry. PMID 31520531 DOI: 10.1111/jnc.14866   
2019 Jin Z, Ke J, Guo P, Wang Y, Wu H. Quercetin improves blood-brain barrier dysfunction in rats with cerebral ischemia reperfusion via Wnt signaling pathway. American Journal of Translational Research. 11: 4683-4695. PMID 31497191   
2019 Yang S, Chen Y, Feng M, Rodriguez L, Wu JQ, Wang MZ. Improving eflornithine oral bioavailability and brain uptake by modulating intercellular junctions with an E-cadherin peptide. Journal of Pharmaceutical Sciences. PMID 31545969 DOI: 10.1016/j.xphs.2019.09.015   
2019 Zhang H, Yang X, Li X, Cheng Y, Zhang H, Chang L, Sun M, Zhang Z, Wang Z, Niu Q, Wang T. Oxidative and nitrosative stress in the neurotoxicity of polybrominated diphenyl ether-153: possible mechanism and potential targeted intervention. Chemosphere. 238: 124602. PMID 31545211 DOI: 10.1016/j.chemosphere.2019.124602   
2019 Chastain-Potts SE, Tesic V, Tat QL, Cabrera OH, Quillinan N, Jevtovic-Todorovic V. Sevoflurane Exposure Results in Sex-Specific Transgenerational Upregulation of Target IEGs in the Subiculum. Molecular Neurobiology. PMID 31512116 DOI: 10.1007/s12035-019-01752-0   
2019 Nishijima S, Sugaya K, Kadekawa K, Ashitomi K, Ueda T, Yamamoto H. Mechanisms underlying the effects of propiverine on bladder activity in rats with pelvic venous congestion and urinary frequency. Biomedical Research (Tokyo, Japan). 40: 145-152. PMID 31413235 DOI: 10.2220/biomedres.40.145   
2019 Zheng H, Ton H, Yang L, Liufu N, Dong Y, Zhang Y, Xie Z. Acute Fasting Does Not Induce Cognitive Impairment in Mice. Frontiers in Neuroscience. 13: 896. PMID 31507368 DOI: 10.3389/fnins.2019.00896   
2019 Wang XG, Zhu DD, Li N, Huang YL, Wang YZ, Zhang T, Wang CM, Wang B, Peng Y, Ge BY, Li S, Zhao J. Scorpion Venom Heat-Resistant Peptide is Neuroprotective against Cerebral Ischemia-Reperfusion Injury in Association with the NMDA-MAPK Pathway. Neuroscience Bulletin. PMID 31502213 DOI: 10.1007/s12264-019-00425-1   
2019 Yousefi-Manesh H, Rashidian A, Hemmati S, Shirooie S, Sadeghi MA, Zarei N, Dehpour AR. Therapeutic effects of modafinil in ischemic stroke; possible role of NF-κB downregulation. Immunopharmacology and Immunotoxicology. 41: 558-564. PMID 31542978 DOI: 10.1080/08923973.2019.1669045   
2019 McVey Neufeld KA, Bienenstock J, Bharwani A, Champagne-Jorgensen K, Mao Y, West C, Liu Y, Surette MG, Kunze W, Forsythe P. Oral selective serotonin reuptake inhibitors activate vagus nerve dependent gut-brain signalling. Scientific Reports. 9: 14290. PMID 31582799 DOI: 10.1038/s41598-019-50807-8