Gary Strichartz - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 
Area:
Persistent pain, Molecular and Cellular Mechanism

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Garibyan L, Moradi Tuchayi S, Wang Y, Khodorova A, Stemmer-Rachamimov A, Purschke M, Osseiran S, Evans CL, Mao J, Strichartz G, Anderson RR. Neural Selective Cryoneurolysis with Ice Slurry Injection in a Rat Model. Anesthesiology. PMID 31977524 DOI: 10.1097/Aln.0000000000003124  0.361
2019 Zinboonyahgoon N, Vlassakov K, Lirk P, Spivey T, King T, Dominici L, Golshan M, Strichartz G, Edwards R, Schreiber K. Benefit of regional anaesthesia on postoperative pain following mastectomy: the influence of catastrophising. British Journal of Anaesthesia. 123: e293-e302. PMID 31331591 DOI: 10.1016/J.Bja.2019.01.041  0.305
2018 Khodorova A, Zhang Y, Nicol G, Strichartz G. Interactions of peripheral endothelin-1 and nerve growth factor as contributors to persistent cutaneous pain. Physiological Research. 67: S215-S225. PMID 29947541 DOI: 10.33549/PHYSIOLRES.933819  0.36
2017 Kays J, Zhang YH, Khorodova A, Strichartz G, Nicol GD. Peripheral Synthesis of an Atypical Protein Kinase C Mediates the Enhancement of Excitability and the Development of Mechanical Hyperalgesia Produced by Nerve Growth Factor. Neuroscience. PMID 29288797 DOI: 10.1016/j.neuroscience.2017.12.030  0.347
2017 Lirk P, Hollmann MW, Strichartz G. The Science of Local Anesthesia: Basic Research, Clinical Application, and Future Directions. Anesthesia and Analgesia. PMID 29189280 DOI: 10.1213/ANE.0000000000002665  0.407
2016 Khodorova A, Nicol GD, Strichartz G. The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor. Neuroscience. PMID 27826102 DOI: 10.1016/j.neuroscience.2016.10.064  0.304
2013 Khodorova A, Nicol GD, Strichartz G. The p75NTR signaling cascade mediates mechanical hyperalgesia induced by nerve growth factor injected into the rat hind paw. Neuroscience. 254: 312-23. PMID 24095693 DOI: 10.1016/j.neuroscience.2013.09.046  0.328
2013 Barreveld A, Witte J, Chahal H, Durieux ME, Strichartz G. Preventive analgesia by local anesthetics: the reduction of postoperative pain by peripheral nerve blocks and intravenous drugs. Anesthesia and Analgesia. 116: 1141-61. PMID 23408672 DOI: 10.1213/ANE.0b013e318277a270  0.379
2013 Leeson S, Strichartz G. Kinetics of uptake and washout of lidocaine in rat sciatic nerve in vitro. Anesthesia and Analgesia. 116: 694-702. PMID 23400993 DOI: 10.1213/ANE.0b013e31827aed25  0.362
2013 Ganesh A, Montmayeur J, Strichartz G. Endothelin-1 nociceptive signaling in keratinocytes may involve sensitization of adenylate cyclase The Journal of Pain. 14: S42. DOI: 10.1016/j.jpain.2013.01.502  0.319
2012 Ohri R, Blaskovich P, Wang JC, Pham L, Nichols G, Hildebrand W, Costa D, Scarborough N, Herman C, Strichartz G. Prolonged nerve block by microencapsulated bupivacaine prevents acute postoperative pain in rats. Regional Anesthesia and Pain Medicine. 37: 607-15. PMID 22996201 DOI: 10.1097/Aap.0B013E3182680F35  0.39
2011 Ji RR, Xu ZZ, Strichartz G, Serhan CN. Emerging roles of resolvins in the resolution of inflammation and pain. Trends in Neurosciences. 34: 599-609. PMID 21963090 DOI: 10.1016/J.Tins.2011.08.005  0.316
2011 Colvin AC, Wang CF, Soens MA, Mitani AA, Strichartz G, Gerner P. Prolonged cutaneous analgesia with transdermal application of amitriptyline and capsaicin. Regional Anesthesia and Pain Medicine. 36: 236-40. PMID 21364497 DOI: 10.1097/AAP.0b013e31820c2c30  0.414
2011 Huang L, Wang CF, Serhan CN, Strichartz G. Enduring prevention and transient reduction of postoperative pain by intrathecal resolvin D1. Pain. 152: 557-65. PMID 21255928 DOI: 10.1016/J.Pain.2010.11.021  0.34
2011 Wang CF, Pancaro C, Gerner P, Strichartz G. Prolonged suppression of postincisional pain by a slow-release formulation of lidocaine. Anesthesiology. 114: 135-49. PMID 21169797 DOI: 10.1097/ALN.0b013e3182001996  0.383
2010 Gerner P, Wang CF, Lee BS, Suzuki S, Degirolami U, Gandhi A, Knaack D, Strichartz G. The relationship between functional sciatic nerve block duration and the rate of release of lidocaine from a controlled-release matrix. Anesthesia and Analgesia. 111: 221-9. PMID 20522702 DOI: 10.1213/ANE.0b013e3181dd2690  0.332
2009 Khodorova A, Zou S, Ren K, Dubner R, Davar G, Strichartz G. Dual Roles for Endothelin-B Receptors in Modulating Adjuvant-Induced Inflammatory Hyperalgesia in Rats. The Open Pain Journal. 2: 30-40. PMID 20559459 DOI: 10.2174/1876386300902010030  0.317
2009 Colucci V, Strichartz G, Jolesz F, Vykhodtseva N, Hynynen K. Focused ultrasound effects on nerve action potential in vitro. Ultrasound in Medicine & Biology. 35: 1737-47. PMID 19647923 DOI: 10.1016/J.Ultrasmedbio.2009.05.002  0.367
2009 Khodorova A, Richter J, Vasko MR, Strichartz G. Early and late contributions of glutamate and CGRP to mechanical sensitization by endothelin-1. The Journal of Pain : Official Journal of the American Pain Society. 10: 740-9. PMID 19559390 DOI: 10.1016/j.jpain.2009.01.265  0.307
2009 Feng B, Strichartz G. Endothelin-1 raises excitability and reduces potassium currents in sensory neurons. Brain Research Bulletin. 79: 345-50. PMID 19409452 DOI: 10.1016/j.brainresbull.2009.04.012  0.359
2009 Wang CF, Djalali AG, Gandhi A, Knaack D, De Girolami U, Strichartz G, Gerner P. An absorbable local anesthetic matrix provides several days of functional sciatic nerve blockade. Anesthesia and Analgesia. 108: 1027-33. PMID 19224820 DOI: 10.1213/ane.0b013e318193596a  0.351
2009 Hans G, Schmidt BL, Strichartz G. Nociceptive sensitization by endothelin-1. Brain Research Reviews. 60: 36-42. PMID 19150466 DOI: 10.1016/J.Brainresrev.2008.12.008  0.307
2009 Khodorova A, Montmayeur JP, Strichartz G. Endothelin receptors and pain. The Journal of Pain : Official Journal of the American Pain Society. 10: 4-28. PMID 19111868 DOI: 10.1016/j.jpain.2008.09.009  0.327
2008 Sugimoto K, Kissin I, Strichartz G. A high concentration of resiniferatoxin inhibits ion channel function in clonal neuroendocrine cells. Anesthesia and Analgesia. 107: 318-24. PMID 18635503 DOI: 10.1213/ane.0b013e31816d140a  0.385
2007 Yanagidate F, Strichartz GR. Local anesthetics. Handbook of Experimental Pharmacology. 95-127. PMID 17087121 DOI: 10.1007/978-3-540-33823-9_4  0.368
2007 Strichartz G. Sodium Channels, Pain, and Analgesia. Edited by Kevin Coward and Mark D. Baker. Chemmedchem. 2: 243-243. DOI: 10.1002/CMDC.200600210  0.364
2006 Amir R, Argoff CE, Bennett GJ, Cummins TR, Durieux ME, Gerner P, Gold MS, Porreca F, Strichartz GR. The role of sodium channels in chronic inflammatory and neuropathic pain. The Journal of Pain : Official Journal of the American Pain Society. 7: S1-29. PMID 16632328 DOI: 10.1016/J.Jpain.2006.01.444  0.328
2004 Ji RR, Strichartz G. Cell signaling and the genesis of neuropathic pain. Science's Stke : Signal Transduction Knowledge Environment. 2004: reE14. PMID 15454629 DOI: 10.1126/stke.2522004re14  0.349
2004 Houck CS, Khodorova A, Reale AM, Strichartz GR, Davar G. Sensory fibers resistant to the actions of tetrodotoxin mediate nocifensive responses to local administration of endothelin-1 in rats. Pain. 110: 719-26. PMID 15288413 DOI: 10.1016/j.pain.2004.05.012  0.302
2004 Son SL, Wong K, Strichartz G. Antagonism by local anesthetics of sodium channel activators in the presence of scorpion toxins: two mechanisms for competitive inhibition. Cellular and Molecular Neurobiology. 24: 565-77. PMID 15233379 DOI: 10.1023/B:CEMN.0000023630.16308.54  0.414
2002 Persaud N, Strichartz GR. Micromolar lidocaine selectively blocks propagating ectopic impulses at a distance from their site of origin. Pain. 99: 333-40. PMID 12237212 DOI: 10.1016/S0304-3959(02)00163-X  0.354
2002 Nau C, Strichartz GR. Drug chirality in anesthesia. Anesthesiology. 97: 497-502. PMID 12151942 DOI: 10.1097/00000542-200208000-00029  0.44
2002 Zhou Z, Davar G, Strichartz G. Endothelin-1 (ET-1) selectively enhances the activation gating of slowly inactivating tetrodotoxin-resistant sodium currents in rat sensory neurons: a mechanism for the pain-inducing actions of ET-1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6325-30. PMID 12151509 DOI: 10.1523/Jneurosci.22-15-06325.2002  0.359
2002 Strichartz GR, Zhou Z, Sinnott C, Khodorova A. Therapeutic concentrations of local anaesthetics unveil the potential role of sodium channels in neuropathic pain. Novartis Foundation Symposium. 241: 189-201; discussion . PMID 11771646  0.329
2001 Zhou QL, Strichartz G, Davar G. Endothelin-1 activates ET(A) receptors to increase intracellular calcium in model sensory neurons. Neuroreport. 12: 3853-7. PMID 11726808 DOI: 10.1097/00001756-200112040-00050  0.322
2001 Khodorova A, Meissner K, Leeson S, Strichartz GR. Lidocaine selectively blocks abnormal impulses arising from noninactivating Na channels. Muscle & Nerve. 24: 634-47. PMID 11317273 DOI: 10.1002/mus.1049  0.35
2000 Nau C, Wang SY, Strichartz GR, Wang GK. Block of human heart hH1 sodium channels by the enantiomers of bupivacaine. Anesthesiology. 93: 1022-33. PMID 11020758 DOI: 10.1097/00000542-200010000-00026  0.56
2000 Vladimirov M, Nau C, Mok WM, Strichartz G. Potency of bupivacaine stereoisomers tested in vitro and in vivo: biochemical, electrophysiological, and neurobehavioral studies. Anesthesiology. 93: 744-55. PMID 10969308 DOI: 10.1097/00000542-200009000-00024  0.62
1999 Nau C, Wang SY, Strichartz GR, Wang GK. Point mutations at N434 in D1-S6 of mu1 Na(+) channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers. Molecular Pharmacology. 56: 404-13. PMID 10419561  0.543
1999 Kohane DS, Kuang Y, Lu NT, Langer R, Strichartz GR, Berde CB. Vanilloid receptor agonists potentiate the in vivo local anesthetic activity of percutaneously injected site 1 sodium channel blockers. Anesthesiology. 90: 524-34. PMID 9952161 DOI: 10.1097/00000542-199902000-00029  0.33
1998 Chamberlain LJ, Yannas IV, Hsu HP, Strichartz G, Spector M. Collagen-GAG substrate enhances the quality of nerve regeneration through collagen tubes up to level of autograft. Experimental Neurology. 154: 315-29. PMID 9878170 DOI: 10.1006/Exnr.1998.6955  0.323
1998 Davar G, Hans G, Fareed MU, Sinnott C, Strichartz G. Behavioral signs of acute pain produced by application of endothelin-1 to rat sciatic nerve. Neuroreport. 9: 2279-83. PMID 9694215 DOI: 10.1097/00001756-199807130-00025  0.394
1998 Kohane DS, Yieh J, Lu NT, Langer R, Strichartz GR, Berde CB. A re-examination of tetrodotoxin for prolonged duration local anesthesia. Anesthesiology. 89: 119-31. PMID 9667302 DOI: 10.1097/00000542-199807000-00019  0.309
1998 Kohane DS, Kuang Y, Langer R, Strichartz GR, Berde CB. VANILLOIDS AND SITE 1 SODIUM CHANNEL TOXINS SYNERGISTICALLY BLOCK SCIATIC NERVE IN VIVO Anesthesiology. 89: 885A. DOI: 10.1097/00000542-199809150-00060  0.321
1998 Nau C, Strichartz GR. MEMBRANE POTENTIAL REVERSES STEREO-SELECTIVITY OF BUPIVACAINE ENANTIOMERS TO BLOCK SODIUM CURRENT IN RAT GH3 CELLS Anesthesiology. 89: 882A. DOI: 10.1097/00000542-199809150-00057  0.52
1997 Vladimirov M, Thalhammer JG, Hunt N, Feldman HS, Strichartz G. Neurophysiologic actions and neurological consequences of veratridine on the rat sciatic nerve. Anesthesiology. 86: 945-56. PMID 9105239 DOI: 10.1097/00000542-199704000-00025  0.354
1995 McHugh J, Mok WM, Wang GK, Strichartz G. Irreversible inhibition of sodium current and batrachotoxin binding by a photoaffinity-derivatized local anesthetic. The Journal of General Physiology. 105: 267-87. PMID 7760019 DOI: 10.1085/jgp.105.2.267  0.313
1995 Strichartz G. Protracted relief of experimental neuropathic pain by systemic local anesthetics. How, where, and when. Anesthesiology. 83: 654-5. PMID 7574043 DOI: 10.1097/00000542-199510000-00002  0.301
1993 Wilder RT, Berde CB, Griggs CT, Chickalingaiah R, Strichartz G. Chronic exposure to lidocaine does not alter flux through sodium channels in cultured neuronal cells. Regional Anesthesia. 18: 283-9. PMID 8268116 DOI: 10.1136/Rapm-00115550-199318050-00004  0.382
1992 Wood MR, DeBin J, Strichartz GR, Pfenninger KH. Plasmalemmal insertion and modification of sodium channels at the nerve growth cone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 2948-59. PMID 1322979 DOI: 10.1523/Jneurosci.12-08-02948.1992  0.402
1992 Lee-Son S, Wang GK, Concus A, Crill E, Strichartz G. Stereoselective inhibition of neuronal sodium channels by local anesthetics. Evidence for two sites of action? Anesthesiology. 77: 324-35. PMID 1322642 DOI: 10.1097/00000542-199208000-00016  0.429
1991 Schneider M, Datta S, Strichartz G. A preferential inhibition of impulses in C-fibers of the rabbit vagus nerve by veratridine, an activator of sodium channels. Anesthesiology. 74: 270-80. PMID 1846725 DOI: 10.1097/00000542-199102000-00013  0.396
1991 Drachman D, Strichartz G. Potassium channel blockers potentiate impulse inhibition by local anesthetics. Anesthesiology. 75: 1051-61. PMID 1741497 DOI: 10.1097/00000542-199112000-00018  0.41
1991 Hahin R, Wang GK, Shapiro BI, Strichartz G. Alterations in sodium channel gating produced by the venom of the marine mollusc Conus striatus. Toxicon : Official Journal of the International Society On Toxinology. 29: 245-59. PMID 1646501 DOI: 10.1016/0041-0101(91)90109-5  0.389
1990 Butterworth JF, Strichartz GR. Molecular mechanisms of local anesthesia: a review. Anesthesiology. 72: 711-34. PMID 2157353  0.301
1987 Butterworth JF, Moran JR, Whitesides GM, Strichartz GR. Limited nerve impulse blockade by "leashed" local anesthetics. Journal of Medicinal Chemistry. 30: 1295-302. PMID 2441052 DOI: 10.1021/Jm00391A006  0.334
1987 Strichartz G, Rando T, Wang GK. An integrated view of the molecular toxinology of sodium channel gating in excitable cells. Annual Review of Neuroscience. 10: 237-67. PMID 2436544 DOI: 10.1146/Annurev.Ne.10.030187.001321  0.403
1986 Strichartz G, Rando T, Hall S, Gitschier J, Hall L, Magnani B, Bay CH. On the mechanism by which saxitoxin binds to and blocks sodium channels. Annals of the New York Academy of Sciences. 479: 96-112. PMID 2434011 DOI: 10.1111/J.1749-6632.1986.Tb15564.X  0.378
1986 Strichartz GR, Wang GK. Rapid voltage-dependent dissociation of scorpion alpha-toxins coupled to Na channel inactivation in amphibian myelinated nerves. The Journal of General Physiology. 88: 413-35. PMID 2428923  0.302
1986 Rando TA, Wang GK, Strichartz GR. The interaction between the activator agents batrachotoxin and veratridine and the gating processes of neuronal sodium channels. Molecular Pharmacology. 29: 467-77. PMID 2422536  0.317
1985 Jackson FR, Gitschier J, Strichartz GR, Hall LM. Genetic modifications of voltage-sensitive sodium channels in Drosophila: gene dosage studies of the seizure locus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 1144-51. PMID 2582101 DOI: 10.1523/Jneurosci.05-05-01144.1985  0.318
1985 Wang GK, Strichartz G. Kinetic analysis of the action of Leiurus scorpion alpha-toxin on ionic currents in myelinated nerve. The Journal of General Physiology. 86: 739-62. PMID 2415671 DOI: 10.1085/Jgp.86.5.739  0.388
1985 Butterworth JF, Moran J, Whitesides G, Strichartz G. BLOCK OF NEURONAL NA+ CHANNELS BY LEASHED LOCAL ANESTHETICS Anesthesiology. 63: A207. DOI: 10.1097/00000542-198509001-00207  0.36
1983 Strichartz G, Bar-Sagi D, Prives J. Differential expression of sodium channel activities during the development of chick skeletal muscle cells in culture. The Journal of General Physiology. 82: 365-84. PMID 6313850 DOI: 10.1085/Jgp.82.3.365  0.367
1982 Wang GK, Strichartz G. Simultaneous modifications of sodium channel gating by two scorpion toxins. Biophysical Journal. 40: 175-9. PMID 6293596 DOI: 10.1016/S0006-3495(82)84473-1  0.416
1981 Hahin R, Strichartz G. Effects of deuterium oxide on the rate and dissociation constants for saxitoxin and tetrodotoxin action. Voltage-clamp studies on frog myelinated nerve. The Journal of General Physiology. 78: 113-39. PMID 6268735 DOI: 10.1085/Jgp.78.2.113  0.391
1981 Cohen I, Attwell D, Strichartz G. The dependence of the maximum rate of rise of the action potential upstroke on membrane properties. Proceedings of the Royal Society of London. Series B, Biological Sciences. 214: 85-98. PMID 6121330 DOI: 10.1098/Rspb.1981.0083  0.319
1980 Strichartz G. Use-dependent conduction block produced by volatile general anesthetic agents. Acta Anaesthesiologica Scandinavica. 24: 402-6. PMID 6970493 DOI: 10.1111/J.1399-6576.1980.Tb01571.X  0.367
1978 Strichartz G, Cohen I. Vmax as a measure of GNa in nerve and cardiac membranes. Biophysical Journal. 23: 153-6. PMID 667304 DOI: 10.1016/S0006-3495(78)85440-X  0.31
1977 Strichartz G. Effects of tertiary local anesthetics and their quaternary derivatives on sodium channels of nerve membranes [proceedings]. Biophysical Journal. 18: 353-4. PMID 890031 DOI: 10.1016/S0006-3495(77)85619-1  0.42
1976 Strichartz G. Molecular mechanisms of nerve block by local anesthetics. Anesthesiology. 45: 421-41. PMID 9844 DOI: 10.1097/00006534-197708000-00125  0.46
1974 Henderson R, Strichartz G. Ion fluxes through the sodium channels of garfish olfactory nerve membranes. The Journal of Physiology. 238: 329-42. PMID 4840874 DOI: 10.1113/Jphysiol.1974.Sp010527  0.545
1974 Henderson R, Ritchie JM, Strichartz GR. Evidence that tetrodotoxin and saxitoxin act at a metal cation binding site in the sodium channels of nerve membrane. Proceedings of the National Academy of Sciences of the United States of America. 71: 3936-40. PMID 4530274 DOI: 10.1073/Pnas.71.10.3936  0.508
1973 Henderson R, Ritchie JM, Strichartz GR. The binding of labelled saxitoxin to the sodium channels in nerve membranes. The Journal of Physiology. 235: 783-804. PMID 4772409 DOI: 10.1113/Jphysiol.1973.Sp010417  0.502
1973 Henderson R, Ritchie JM, Strichartz GR. The binding of labelled saxitoxin to mammalian non-myelinated nerve fibres. The Journal of Physiology. 232: 53P-54P. PMID 4733507  0.444
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