Giovanni Biggio - Publications

Affiliations: 
University of Cagliari 

324 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Licheri V, Talani G, Biggio G, Sanna E. Bi-directional modulation of hyperpolarization-activated cation currents (I) by ethanol in rat hippocampal CA3 pyramidal neurons. Neuropharmacology. 227: 109423. PMID 36690323 DOI: 10.1016/j.neuropharm.2023.109423  0.521
2022 Talani G, Biggio F, Gorule AA, Licheri V, Saolini E, Colombo D, Sarigu G, Petrella M, Vedele F, Biggio G, Sanna E. Sex-dependent changes of hippocampal synaptic plasticity and cognitive performance in C57BL/6J mice exposed to neonatal repeated maternal separation. Neuropharmacology. 222: 109301. PMID 36336069 DOI: 10.1016/j.neuropharm.2022.109301  0.489
2021 Mostallino MC, Secci PP, Paci E, Mura ML, Maciocco E, Sanna E, Biggio G. The Plastic and Functional Changes in Hippocampal Neurons During Pregnancy, Delivery and Postpartum are Reversed by Offspring Deprivation Current Psychopharmacology. 10: 73-83. DOI: 10.2174/2211556009999200819102313  0.499
2019 Talani G, Biggio F, Mostallino MC, Locci V, Porcedda C, Boi L, Saolini E, Piras R, Sanna E, Biggio G. Treatment with gut bifidobacteria improves hippocampal plasticity and cognitive behavior in adult healthy rats. Neuropharmacology. 165: 107909. PMID 31857091 DOI: 10.1016/J.Neuropharm.2019.107909  0.317
2018 Cannizzaro C, Talani G, Brancato A, Mulas G, Spiga S, Antonietta De Luca M, Sanna A, Anna Maria Marino R, Biggio G, Sanna E, Diana M. Dopamine restores limbic memory loss, dendritic spine structure and NMDAR-dependent LTD in the nucleus accumbens of alcohol-withdrawn rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30446531 DOI: 10.1523/Jneurosci.1377-18.2018  0.545
2016 Talani G, Biggio F, Licheri V, Locci V, Biggio G, Sanna E. Isolation Rearing Reduces Neuronal Excitability in Dentate Gyrus Granule Cells of Adolescent C57BL/6J Mice: Role of GABAergic Tonic Currents and Neurosteroids. Frontiers in Cellular Neuroscience. 10: 158. PMID 27378855 DOI: 10.3389/Fncel.2016.00158  0.576
2016 Cappelli A, Anzini M, Castriconi F, Grisci G, Paolino M, Braile C, Valenti S, Giuliani G, Vomero S, Di Capua A, Betti L, Giannaccini G, Lucacchini A, Ghelardini C, Di Cesare Mannelli L, ... ... Biggio G, et al. Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors. Journal of Medicinal Chemistry. PMID 26982523 DOI: 10.1021/Acs.Jmedchem.6B00034  0.354
2015 Licheri V, Talani G, Gorule AA, Mostallino MC, Biggio G, Sanna E. Plasticity of GABAA Receptors during Pregnancy and Postpartum Period: From Gene to Function. Neural Plasticity. 2015: 170435. PMID 26413323 DOI: 10.1155/2015/170435  0.614
2015 Talani G, Licheri V, Biggio F, Locci V, Mostallino MC, Secci PP, Melis V, Dazzi L, Carta G, Banni S, Biggio G, Sanna E. Enhanced Glutamatergic Synaptic Plasticity in the Hippocampal CA1 Field of Food-Restricted Rats: Involvement of CB1 Receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26354043 DOI: 10.1038/Npp.2015.280  0.595
2014 Spiga S, Talani G, Mulas G, Licheri V, Fois GR, Muggironi G, Masala N, Cannizzaro C, Biggio G, Sanna E, Diana M. Hampered long-term depression and thin spine loss in the nucleus accumbens of ethanol-dependent rats. Proceedings of the National Academy of Sciences of the United States of America. 111: E3745-54. PMID 25122682 DOI: 10.1073/Pnas.1406768111  0.576
2014 Mascia MP, Ledda G, Orrù A, Marongiu A, Loriga G, Maciocco E, Biggio G, Ruiu S. Differential modulation of GABA(A) receptor function by aryl pyrazoles. European Journal of Pharmacology. 733: 1-6. PMID 24704372 DOI: 10.1016/J.Ejphar.2014.03.039  0.412
2014 Biggio G, Pisu MG, Biggio F, Serra M. Allopregnanolone modulation of HPA axis function in the adult rat. Psychopharmacology. 231: 3437-44. PMID 24658404 DOI: 10.1007/S00213-014-3521-6  0.458
2014 Dazzi L, Talani G, Biggio F, Utzeri C, Lallai V, Licheri V, Lutzu S, Mostallino MC, Secci PP, Biggio G, Sanna E. Involvement of the cannabinoid CB1 receptor in modulation of dopamine output in the prefrontal cortex associated with food restriction in rats. Plos One. 9: e92224. PMID 24632810 DOI: 10.1371/Journal.Pone.0092224  0.608
2014 Talani G, Licheri V, Masala N, Follesa P, Mostallino MC, Biggio G, Sanna E. Increased voluntary ethanol consumption and changes in hippocampal synaptic plasticity in isolated C57BL/6J mice. Neurochemical Research. 39: 997-1004. PMID 24343529 DOI: 10.1007/S11064-013-1216-8  0.725
2014 Licheri V, Talani G, Di Lucente J, Biggio G, Sanna E. P.1.g.089 Ethanol modulates in a biphasic manner hyperpolarisation-activated currents (Ih) in rat hippocampal CA3 pyramidal neurons European Neuropsychopharmacology. 24: S255-S256. DOI: 10.1016/S0924-977X(14)70400-6  0.569
2013 Avolio E, Facciolo RM, Alò R, Mele M, Carelli A, Canonaco A, Mosciaro L, Talani G, Biggio G, Sanna E, Mahata SK, Canonaco M. Expression variations of chromogranin A and α1,2,4 GABA(A)Rs in discrete limbic and brainstem areas rescue cardiovascular alterations. Neuroscience Research. 77: 8-15. PMID 23916832 DOI: 10.1016/J.Neures.2013.07.006  0.615
2013 Licheri V, Talani G, Dazzi L, Biggio F, Utzeri C, Lallai V, Lutzu S, Biggio G, Sanna E. P.1.005 Role of cannabinoid CB1 receptors in modulation of dopamine output in the prefrontal cortex associated with food restriction in rats European Neuropsychopharmacology. 23: S7. DOI: 10.1016/S0924-977X(13)70007-5  0.582
2012 Paola Mascia M, Fabbri D, Antonietta Dettori M, Ledda G, Delogu G, Biggio G. Hydroxylated biphenyl derivatives are positive modulators of human GABA(A) receptors. European Journal of Pharmacology. 693: 45-50. PMID 22959356 DOI: 10.1016/J.Ejphar.2012.07.048  0.432
2012 Giusi G, Alò R, Avolio E, Zizza M, Facciolo RM, Talani G, Biggio G, Sanna E, Canonaco M. Brain excitatory/inhibitory circuits cross-talking with chromogranin A during hypertensive and hibernating states. Current Medicinal Chemistry. 19: 4093-114. PMID 22834800 DOI: 10.2174/092986712802429993  0.563
2012 Ahboucha S, Talani G, Fanutza T, Sanna E, Biggio G, Gamrani H, Butterworth RF. Reduced brain levels of DHEAS in hepatic coma patients: significance for increased GABAergic tone in hepatic encephalopathy. Neurochemistry International. 61: 48-53. PMID 22490610 DOI: 10.1016/J.Neuint.2012.03.020  0.614
2011 Talani G, Biggio G, Sanna E. Enhanced Sensitivity to Ethanol-Induced Inhibition of LTP in CA1 Pyramidal Neurons of Socially Isolated C57BL/6J Mice: Role of Neurosteroids. Frontiers in Endocrinology. 2: 56. PMID 22649377 DOI: 10.3389/Fendo.2011.00056  0.559
2011 Anzini M, Valenti S, Braile C, Cappelli A, Vomero S, Alcaro S, Ortuso F, Marinelli L, Limongelli V, Novellino E, Betti L, Giannaccini G, Lucacchini A, Daniele S, Martini C, ... ... Biggio G, et al. New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds. Journal of Medicinal Chemistry. 54: 5694-711. PMID 21751815 DOI: 10.1021/Jm2001597  0.369
2011 Dazzi L, Matzeu A, Biggio G. Role of ionotropic glutamate receptors in the regulation of hippocampal norepinephrine output in vivo. Brain Research. 1386: 41-9. PMID 21362410 DOI: 10.1016/J.Brainres.2011.02.065  0.396
2011 Sanna E, Talani G, Obili N, Mascia MP, Mostallino MC, Secci PP, Pisu MG, Biggio F, Utzeri C, Olla P, Biggio G, Follesa P. Voluntary Ethanol Consumption Induced by Social Isolation Reverses the Increase of α(4)/δ GABA(A) Receptor Gene Expression and Function in the Hippocampus of C57BL/6J Mice. Frontiers in Neuroscience. 5: 15. PMID 21347217 DOI: 10.3389/Fnins.2011.00015  0.746
2011 Secci P, Mostallino M, Mura M, Talani G, Sanna E, Biggio G. P.1.c.061 Changes in hippocampal plasticity and neurogenesis during pregnancy and post partum are reversed by offspring separation European Neuropsychopharmacology. 21: S288. DOI: 10.1016/S0924-977X(11)70452-7  0.516
2011 Secci P, Mostallino M, Mura M, Talani G, Sanna E, Biggio G. P.1.012 Changes in hippocampal plasticity during pregnancy and post partum are reversed by offspring separation European Neuropsychopharmacology. 21: S11-S12. DOI: 10.1016/S0924-977X(11)70013-X  0.518
2011 Serra M, Pisu MG, Mostallino MC, Sanna E, Biggio G. Social isolation stress-induced changes in allopregnanolone modulate gabaa receptor plasticity and function Translational Neuroscience in Animal Research: Advancement, Challenges, and Research Ethics. 55-69.  0.526
2010 Calza A, Sogliano C, Santoru F, Marra C, Angioni MM, Mostallino MC, Biggio G, Concas A. Neonatal exposure to estradiol in rats influences neuroactive steroid concentrations, GABAA receptor expression, and behavioral sensitivity to anxiolytic drugs. Journal of Neurochemistry. 113: 1285-95. PMID 20345753 DOI: 10.1111/J.1471-4159.2010.06696.X  0.457
2010 Matrisciano F, Nasca C, Molinaro G, Riozzi B, Scaccianoce S, Raggi MA, Mercolini L, Biagioni F, Mathè AA, Sanna E, Maciocco E, Pignatelli M, Biggio G, Nicoletti F. Enhanced expression of the neuronal K+/Cl- cotransporter, KCC2, in spontaneously depressed Flinders Sensitive Line rats. Brain Research. 1325: 112-20. PMID 20153734 DOI: 10.1016/J.Brainres.2010.02.017  0.607
2010 Santoru F, Calza A, Sogliano C, Berretti R, Langiu M, Biggio G, Concas A. P.2.031 Neonatal estradiol administration to female rats alters adult benzodiazepine sensitivity European Neuropsychopharmacology. 20. DOI: 10.1016/S0924-977X(10)70065-1  0.306
2010 Utzeri C, Biggio F, Olla P, Follesa P, Biggio G. P.1.029 Vagus nerve stimulation induces cell proliferation and changes in neuronal morphology in the rat hippocampus European Neuropsychopharmacology. 20. DOI: 10.1016/S0924-977X(10)70031-6  0.631
2009 Morrow AL, Biggio G, Serra M, Becker HC, Lopez MF, Porcu P, Alward SE, O'Buckley TK. The role of neuroactive steroids in ethanol/stress interactions: proceedings of symposium VII at the Volterra conference on alcohol and stress, May 2008. Alcohol (Fayetteville, N.Y.). 43: 521-30. PMID 19913195 DOI: 10.1016/J.Alcohol.2009.04.002  0.369
2009 Mostallino MC, Sanna E, Concas A, Biggio G, Follesa P. Plasticity and function of extrasynaptic GABA(A) receptors during pregnancy and after delivery. Psychoneuroendocrinology. 34: S74-83. PMID 19608348 DOI: 10.1016/J.Psyneuen.2009.06.013  0.787
2009 Biggio G, Cristina Mostallino M, Follesa P, Concas A, Sanna E. GABA(A) receptor function and gene expression during pregnancy and postpartum. International Review of Neurobiology. 85: 73-94. PMID 19607962 DOI: 10.1016/S0074-7742(09)85006-X  0.774
2009 Sanna E, Mostallino MC, Murru L, Carta M, Talani G, Zucca S, Mura ML, Maciocco E, Biggio G. Changes in expression and function of extrasynaptic GABAA receptors in the rat hippocampus during pregnancy and after delivery. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1755-65. PMID 19211882 DOI: 10.1523/Jneurosci.3684-08.2009  0.652
2008 Carta M, Murru L, Barabino E, Talani G, Sanna E, Biggio G. Isoniazid-induced reduction in GABAergic neurotransmission alters the function of the cerebellar cortical circuit. Neuroscience. 154: 710-9. PMID 18456415 DOI: 10.1016/J.Neuroscience.2008.02.024  0.61
2008 Sekimata K, Hatano K, Ogawa M, Abe J, Magata Y, Biggio G, Serra M, Laquintana V, Denora N, Latrofa A, Trapani G, Liso G, Ito K. Radiosynthesis and in vivo evaluation of N-[11C]methylated imidazopyridineacetamides as PET tracers for peripheral benzodiazepine receptors. Nuclear Medicine and Biology. 35: 327-34. PMID 18355688 DOI: 10.1016/J.Nucmedbio.2007.12.005  0.312
2008 Tuveri A, Paoletti AM, Orrù M, Melis GB, Marotto MF, Zedda P, Marrosu F, Sogliano C, Marra C, Biggio G, Concas A. Reduced serum level of THDOC, an anticonvulsant steroid, in women with perimenstrual catamenial epilepsy. Epilepsia. 49: 1221-9. PMID 18325018 DOI: 10.1111/J.1528-1167.2008.01555.X  0.306
2008 Eva C, Mele P, Collura D, Nai A, Pisu MG, Serra M, Biggio G. Modulation of neuropeptide Y and Y1 receptor expression in the amygdala by fluctuations in the brain content of neuroactive steroids during ethanol drinking discontinuation in Y1R/LacZ transgenic mice. Journal of Neurochemistry. 104: 1043-54. PMID 18036156 DOI: 10.1111/J.1471-4159.2007.05077.X  0.363
2008 Serra M, Pisu MG, Mostallino MC, Sanna E, Biggio G. Changes in neuroactive steroid content during social isolation stress modulate GABAA receptor plasticity and function. Brain Research Reviews. 57: 520-30. PMID 17920688 DOI: 10.1016/J.Brainresrev.2007.06.029  0.609
2008 Serra M, Biggio G. Social isolation alters GABAA receptors plasticity and function: effect of voluntary consumption of ethanol Annals of General Psychiatry. 7: 1-1. DOI: 10.1186/1744-859X-7-S1-S25  0.414
2008 Biggio G, Mostallino M, Serra M. S.24.02 Chronic stress changes neurosteroids content and neuronal plasticity in the rat brain European Neuropsychopharmacology. 18. DOI: 10.1016/S0924-977X(08)70207-4  0.321
2008 Mele P, Nai A, Serra M, Pisu MG, Eva C, Biggio G. P.2.27 Role of neurosteroids in the modulation of neuropeptide Y Y1 receptor neurotransmission during ethanol and ghb withdrawal European Neuropsychopharmacology. 18. DOI: 10.1016/S0924-977X(08)70068-3  0.36
2008 Calza A, Sogliano C, Santoru F, Angioni MM, Biggio G, Concas A. P.1.08 Reduction in neuroactive steroids levels, induced by neonatal exposure to estrogen, changes GABAA receptor plasticity European Neuropsychopharmacology. 18. DOI: 10.1016/S0924-977X(08)70009-9  0.366
2007 Follesa P, Biggio F, Gorini G, Caria S, Talani G, Dazzi L, Puligheddu M, Marrosu F, Biggio G. Vagus nerve stimulation increases norepinephrine concentration and the gene expression of BDNF and bFGF in the rat brain. Brain Research. 1179: 28-34. PMID 17920573 DOI: 10.1016/J.Brainres.2007.08.045  0.624
2007 Biggio G, Concas A, Follesa P, Sanna E, Serra M. Stress, ethanol, and neuroactive steroids. Pharmacology & Therapeutics. 116: 140-71. PMID 17555824 DOI: 10.1016/J.Pharmthera.2007.04.005  0.738
2007 Denora N, Laquintana V, Lopedota A, Serra M, Dazzi L, Biggio G, Pal D, Mitra AK, Latrofa A, Trapani G, Liso G. Novel L-Dopa and dopamine prodrugs containing a 2-phenyl-imidazopyridine moiety. Pharmaceutical Research. 24: 1309-24. PMID 17404814 DOI: 10.1007/S11095-007-9255-Y  0.319
2007 Mascia MP, Bachis E, Obili N, Maciocco E, Cocco GA, Sechi GP, Biggio G. Thiocolchicoside inhibits the activity of various subtypes of recombinant GABA(A) receptors expressed in Xenopus laevis oocytes. European Journal of Pharmacology. 558: 37-42. PMID 17234181 DOI: 10.1016/J.Ejphar.2006.11.076  0.502
2007 Dazzi L, Seu E, Cherchi G, Barbieri PP, Matzeu A, Biggio G. Estrous cycle-dependent changes in basal and ethanol-induced activity of cortical dopaminergic neurons in the rat. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 892-901. PMID 16841076 DOI: 10.1038/Sj.Npp.1301150  0.4
2007 Serra M, Sanna E, Mostallino MC, Biggio G. Social isolation stress and neuroactive steroids. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 17: 1-11. PMID 16626946 DOI: 10.1016/J.Euroneuro.2006.03.004  0.619
2007 Mostallino M, Mura M, Maciocco E, Murru L, Sanna E, Biggio G. P.1.17 Progesterone induced-changes in gene expression of delta subunit GABAA receptor in rat hippocampal neurons in culture European Neuropsychopharmacology. 17: S15-S16. DOI: 10.1016/S0924-977X(07)70018-4  0.613
2007 Pisu MG, Biggio G, Serra M. S.04.04 Social isolation alters GABAA receptors plasticity and function: effect of ethanol European Neuropsychopharmacology. 17. DOI: 10.1016/S0924-977X(07)70017-2  0.365
2006 Pisu MG, Floris I, Maciocco E, Serra M, Biggio G. Anticipation and consumption of food each increase the concentration of neuroactive steroids in rat brain and plasma. Pharmacology, Biochemistry, and Behavior. 85: 76-81. PMID 16938341 DOI: 10.1016/J.Pbb.2006.07.011  0.351
2006 Mostallino MC, Mura ML, Maciocco E, Murru L, Sanna E, Biggio G. Changes in expression of the delta subunit of the GABA (A) receptor and in receptor function induced by progesterone exposure and withdrawal. Journal of Neurochemistry. 99: 321-32. PMID 16879715 DOI: 10.1111/J.1471-4159.2006.04055.X  0.665
2006 Rapkin AJ, Biggio G, Concas A. Oral contraceptives and neuroactive steroids. Pharmacology, Biochemistry, and Behavior. 84: 628-34. PMID 16854457 DOI: 10.1016/J.Pbb.2006.06.008  0.35
2006 Eva C, Oberto A, Mele P, Serra M, Biggio G. Role of brain neuroactive steroids in the functional interplay between the GABA(A) and the NPY-Y1 receptor mediated signals in the amygdala. Pharmacology, Biochemistry, and Behavior. 84: 568-80. PMID 16824587 DOI: 10.1016/J.Pbb.2006.05.014  0.418
2006 Carta M, Murru L, Botta P, Talani G, Sechi G, De Riu P, Sanna E, Biggio G. The muscle relaxant thiocolchicoside is an antagonist of GABAA receptor function in the central nervous system. Neuropharmacology. 51: 805-15. PMID 16806306 DOI: 10.1016/J.Neuropharm.2006.05.023  0.657
2006 Serra M, Mostallino MC, Talani G, Pisu MG, Carta M, Mura ML, Floris I, Maciocco E, Sanna E, Biggio G. Social isolation-induced increase in alpha and delta subunit gene expression is associated with a greater efficacy of ethanol on steroidogenesis and GABA receptor function. Journal of Neurochemistry. 98: 122-33. PMID 16805802 DOI: 10.1111/J.1471-4159.2006.03850.X  0.674
2006 Rapkin AJ, Morgan M, Sogliano C, Biggio G, Concas A. Decreased neuroactive steroids induced by combined oral contraceptive pills are not associated with mood changes. Fertility and Sterility. 85: 1371-8. PMID 16580672 DOI: 10.1016/J.Fertnstert.2005.10.031  0.301
2006 Paoletti AM, Romagnino S, Contu R, Orrù MM, Marotto MF, Zedda P, Lello S, Biggio G, Concas A, Melis GB. Observational study on the stability of the psychological status during normal pregnancy and increased blood levels of neuroactive steroids with GABA-A receptor agonist activity. Psychoneuroendocrinology. 31: 485-92. PMID 16406349 DOI: 10.1016/J.Psyneuen.2005.11.006  0.309
2006 Follesa P, Biggio F, Talani G, Murru L, Serra M, Sanna E, Biggio G. Neurosteroids, GABAA receptors, and ethanol dependence. Psychopharmacology. 186: 267-80. PMID 16163526 DOI: 10.1007/S00213-005-0126-0  0.767
2006 Concas A, Sogliano C, Porcu P, Marra C, Brundu A, Biggio G. Neurosteroids in nicotine and morphine dependence. Psychopharmacology. 186: 281-92. PMID 16133140 DOI: 10.1007/S00213-005-0111-7  0.318
2006 Follesa P, Biggio F, Gorini G, Caria S, Marrosu F, Biggio G. S.07.04 Vagus nerve stimulation increases neurotrophins gene expression and alters cell proliferation in the rat hippocampus European Neuropsychopharmacology. 16. DOI: 10.1016/S0924-977X(06)70047-5  0.623
2006 Sanna E, Follesa P, Biggio G. The neurobiology of GABA receptors Psychopharmacogenetics. 421-442. DOI: 10.1007/0-387-34577-2_15  0.755
2005 Serra M, Pisu MG, Floris I, Biggio G. Social isolation-induced changes in the hypothalamic-pituitary-adrenal axis in the rat. Stress (Amsterdam, Netherlands). 8: 259-64. PMID 16423714 DOI: 10.1080/10253890500495244  0.311
2005 Sanna E, Busonero F, Talani G, Mostallino MC, Mura ML, Pisu MG, Maciocco E, Serra M, Biggio G. Low tolerance and dependence liabilities of etizolam: molecular, functional, and pharmacological correlates. European Journal of Pharmacology. 519: 31-42. PMID 16107249 DOI: 10.1016/J.Ejphar.2005.06.047  0.622
2005 Purdy RH, Valenzuela CF, Janak PH, Finn DA, Biggio G, Bäckström T. Neuroactive steroids and ethanol. Alcoholism, Clinical and Experimental Research. 29: 1292-8. PMID 16088987 DOI: 10.1097/01.Alc.0000171486.97638.Bc  0.35
2005 Follesa P, Mostallino MC, Biggio F, Gorini G, Caria S, Busonero F, Murru L, Mura ML, Sanna E, Biggio G. Distinct patterns of expression and regulation of GABA receptors containing the delta subunit in cerebellar granule and hippocampal neurons. Journal of Neurochemistry. 94: 659-71. PMID 16000147 DOI: 10.1111/J.1471-4159.2005.03303.X  0.766
2005 Mascia MP, Asproni B, Busonero F, Talani G, Maciocco E, Pau A, Cerri R, Sanna E, Biggio G. Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors. European Journal of Pharmacology. 516: 204-11. PMID 15967425 DOI: 10.1016/J.Ejphar.2005.05.006  0.649
2005 Ferlin MG, Chiarelotto G, Dall'Acqua S, Maciocco E, Mascia MP, Pisu MG, Biggio G. Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity. Bioorganic & Medicinal Chemistry. 13: 3531-41. PMID 15848766 DOI: 10.1016/J.Bmc.2005.02.042  0.323
2005 Dazzi L, Seu E, Cherchi G, Biggio G. Chronic administration of the SSRI fluvoxamine markedly and selectively reduces the sensitivity of cortical serotonergic neurons to footshock stress. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 15: 283-90. PMID 15820417 DOI: 10.1016/J.Euroneuro.2004.11.003  0.326
2005 Asproni B, Talani G, Busonero F, Pau A, Sanna S, Cerri R, Mascia MP, Sanna E, Biggio G. Synthesis, structure-activity relationships at the GABA(A) receptor in rat brain, and differential electrophysiological profile at the recombinant human GABA(A) receptor of a series of substituted 1,2-diphenylimidazoles. Journal of Medicinal Chemistry. 48: 2638-45. PMID 15801854 DOI: 10.1021/Jm049120Y  0.661
2005 Trapani G, Laquintana V, Denora N, Trapani A, Lopedota A, Latrofa A, Franco M, Serra M, Pisu MG, Floris I, Sanna E, Biggio G, Liso G. Structure-activity relationships and effects on neuroactive steroid synthesis in a series of 2-phenylimidazo[1,2-a]pyridineacetamide peripheral benzodiazepine receptors ligands. Journal of Medicinal Chemistry. 48: 292-305. PMID 15634024 DOI: 10.1021/Jm049610Q  0.585
2005 Trapani G, Latrofa A, Denora N, Cellamare S, Maccallini C, Dazzi L, Biggio G, Liso G. Preformulation studies and estimation of brain penetration for two alpidem analogues having anticonvulsant activity Journal of Drug Delivery Science and Technology. 15: 331-337. DOI: 10.1016/S1773-2247(05)50061-3  0.338
2005 Carta M, Mura ML, Mostallino MC, Caria S, Gorini G, Biggio E, Follesa P, Talani G, Busonero E, Sanna E, Biggio G. P.1.15 Differential alterations in GABAA receptorexpression and function induced by ethanol of hippocampal and cerebellar granule cells European Neuropsychopharmacology. 15. DOI: 10.1016/S0924-977X(05)80120-8  0.721
2004 Follesa P, Biggio F, Caria S, Gorini G, Biggio G. Modulation of GABA(A) receptor gene expression by allopregnanolone and ethanol. European Journal of Pharmacology. 500: 413-25. PMID 15464049 DOI: 10.1016/J.Ejphar.2004.07.041  0.737
2004 Sanna E, Talani G, Busonero F, Pisu MG, Purdy RH, Serra M, Biggio G. Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6521-30. PMID 15269263 DOI: 10.1523/Jneurosci.0075-04.2004  0.688
2004 Monteleone P, Fabrazzo M, Serra M, Tortorella A, Pisu MG, Biggio G, Maj M. Long-term treatment with clozapine does not affect morning circulating levels of allopregnanolone and THDOC in patients with schizophrenia: a preliminary study. Journal of Clinical Psychopharmacology. 24: 437-40. PMID 15232336 DOI: 10.1097/01.Jcp.0000130552.78501.1A  0.336
2004 Mostallino MC, Mascia MP, Pisu MG, Busonero F, Talani G, Biggio G. Inhibition by miltirone of up-regulation of GABAA receptor alpha4 subunit mRNA by ethanol withdrawal in hippocampal neurons. European Journal of Pharmacology. 494: 83-90. PMID 15212961 DOI: 10.1016/J.Ejphar.2004.04.021  0.527
2004 Mele P, Oberto A, Serra M, Pisu MG, Floris I, Biggio G, Eva C. Increased expression of the gene for the Y1 receptor of neuropeptide Y in the amygdala and paraventricular nucleus of Y1R/LacZ transgenic mice in response to restraint stress. Journal of Neurochemistry. 89: 1471-8. PMID 15189350 DOI: 10.1111/J.1471-4159.2004.02444.X  0.377
2004 Porcu P, Sogliano C, Ibba C, Piredda M, Tocco S, Marra C, Purdy RH, Biggio G, Concas A. Failure of gamma-hydroxybutyric acid both to increase neuroactive steroid concentrations in adrenalectomized-orchiectomized rats and to induce tolerance to its steroidogenic effect in intact animals. Brain Research. 1012: 160-8. PMID 15158173 DOI: 10.1016/J.Brainres.2004.03.059  0.394
2004 Serra M, Pisu MG, Floris I, Floris S, Cannas E, Mossa A, Trapani G, Latrofa A, Purdy RH, Biggio G. Social isolation increases the response of peripheral benzodiazepine receptors in the rat. Neurochemistry International. 45: 141-8. PMID 15082231 DOI: 10.1016/J.Neuint.2003.11.013  0.371
2004 Paoletti AM, Lello S, Fratta S, Orrù M, Ranuzzi F, Sogliano C, Concas A, Biggio G, Melis GB. Psychological effect of the oral contraceptive formulation containing 3 mg of drospirenone plus 30 microg of ethinyl estradiol. Fertility and Sterility. 81: 645-51. PMID 15037415 DOI: 10.1016/J.Fertnstert.2003.08.030  0.301
2004 Dazzi L, Seu E, Cherchi G, Biggio G. Inhibition of stress-induced dopamine output in the rat prefrontal cortex by chronic treatment with olanzapine. Biological Psychiatry. 55: 477-83. PMID 15023575 DOI: 10.1016/J.Biopsych.2003.11.020  0.347
2004 Follesa P, Biggio F, Mancuso L, Cabras S, Caria S, Gorini G, Manca A, Orru A, Biggio G. Ethanol withdrawal-induced up-regulation of the alpha2 subunit of the GABAA receptor and its prevention by diazepam or gamma-hydroxybutyric acid. Brain Research. Molecular Brain Research. 120: 130-7. PMID 14741402 DOI: 10.1016/J.Molbrainres.2003.10.011  0.709
2004 Biggio G, Follesa P, Sanna E. S11 Role Of Neurosteroids In Ethanol Dependence And Gabaa Receptor Plasticity Behavioural Pharmacology. 15. DOI: 10.1097/00008877-200409000-00023  0.739
2004 Biggio G, Talani G, Busonero F, Pisu MG, Purdy RH, Serra M, Sanna E. ROLE OF NEUROSTEROIDS IN ETHANOL DEPENDENCE AND GABAA RECEPTOR PLASTICITY. Alcoholism: Clinical & Experimental Research. 28: 79A. DOI: 10.1097/00000374-200408002-00437  0.603
2004 Sanna E, Talani G, Busonero F, Pisu MG, Purdy RH, Serra M, Biggio G. ETHANOL FACILITATION OF GABA-A RECEPTOR FUNCTION IN RAT HIPPOCAMPAL NEURONS: ROLE OF NEUROSTEROIDOGENESIS. Alcoholism: Clinical & Experimental Research. 28: 73A. DOI: 10.1097/00000374-200408002-00400  0.665
2004 Biggio G, Follesa P, Mostallino M, Sanna E. Ethanol exposure and withdrawal differentially affect the GABA - A receptor plasticity and function in two different neuronal populations Neuropsychopharmacology. 29. DOI: 10.1038/Sj.Npp.1300645  0.759
2004 Dazzi L, Seu E, Cherchi G, Biggio G. S.4.03 Long-term administration of olanzapine or clozapine, but not haloperidol, antagonizes the stress-induced increase in dopamine output in the rat prefrontal cortex European Neuropsychopharmacology. 14. DOI: 10.1016/S0924-977X(04)90081-8  0.319
2003 Sanna E, Mostallino MC, Busonero F, Talani G, Tranquilli S, Mameli M, Spiga S, Follesa P, Biggio G. Changes in GABA(A) receptor gene expression associated with selective alterations in receptor function and pharmacology after ethanol withdrawal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11711-24. PMID 14684873 DOI: 10.1523/Jneurosci.23-37-11711.2003  0.786
2003 Biggio G, Dazzi L, Biggio F, Mancuso L, Talani G, Busonero F, Mostallino MC, Sanna E, Follesa P. Molecular mechanisms of tolerance to and withdrawal of GABA(A) receptor modulators. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 13: 411-23. PMID 14636957 DOI: 10.1016/J.Euroneuro.2003.08.002  0.784
2003 Carotti A, Altomare C, Savini L, Chiasserini L, Pellerano C, Mascia MP, Maciocco E, Busonero F, Mameli M, Biggio G, Sanna E. High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3-c]quinolin-3-ones. Bioorganic & Medicinal Chemistry. 11: 5259-72. PMID 14604690 DOI: 10.1016/S0968-0896(03)00527-3  0.617
2003 Altomare C, Trapani G, Latrofa A, Serra M, Sanna E, Biggio G, Liso G. Highly water-soluble derivatives of the anesthetic agent propofol: in vitro and in vivo evaluation of cyclic amino acid esters. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 20: 17-26. PMID 13678789 DOI: 10.1016/S0928-0987(03)00161-1  0.586
2003 Dazzi L, Seu E, Cherchi G, Biggio G. Antagonism of the stress-induced increase in cortical norepinephrine output by the selective norepinephrine reuptake inhibitor reboxetine. European Journal of Pharmacology. 476: 55-61. PMID 12969749 DOI: 10.1016/S0014-2999(03)02130-7  0.359
2003 Marrosu F, Serra A, Maleci A, Puligheddu M, Biggio G, Piga M. Correlation between GABA(A) receptor density and vagus nerve stimulation in individuals with drug-resistant partial epilepsy. Epilepsy Research. 55: 59-70. PMID 12948617 DOI: 10.1016/S0920-1211(03)00107-4  0.427
2003 Gupta M, Hogema BM, Grompe M, Bottiglieri TG, Concas A, Biggio G, Sogliano C, Rigamonti AE, Pearl PL, Snead OC, Jakobs C, Gibson KM. Murine succinate semialdehyde dehydrogenase deficiency. Annals of Neurology. 54: S81-90. PMID 12891658 DOI: 10.1002/Ana.10625  0.422
2003 Trapani G, Latrofa A, Franco M, Carrieri A, Cellamare S, Serra M, Sanna E, Biggio G, Liso G. Alpidem analogues containing a GABA or glycine moiety as new anticonvulsant agents. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 18: 231-40. PMID 12659934 DOI: 10.1016/S0928-0987(03)00002-2  0.651
2003 Follesa P, Mancuso L, Biggio F, Mostallino MC, Manca A, Mascia MP, Busonero F, Talani G, Sanna E, Biggio G. Gamma-hydroxybutyric acid and diazepam antagonize a rapid increase in GABA(A) receptors alpha(4) subunit mRNA abundance induced by ethanol withdrawal in cerebellar granule cells. Molecular Pharmacology. 63: 896-907. PMID 12644591 DOI: 10.1124/Mol.63.4.896  0.769
2003 Serra M, Pisu MG, Floris I, Cara V, Purdy RH, Biggio G. Social isolation-induced increase in the sensitivity of rats to the steroidogenic effect of ethanol. Journal of Neurochemistry. 85: 257-63. PMID 12641747 DOI: 10.1046/J.1471-4159.2003.01680.X  0.369
2003 Porcu P, Sogliano C, Cinus M, Purdy RH, Biggio G, Concas A. Nicotine-induced changes in cerebrocortical neuroactive steroids and plasma corticosterone concentrations in the rat. Pharmacology, Biochemistry, and Behavior. 74: 683-90. PMID 12543235 DOI: 10.1016/S0091-3057(02)01065-1  0.338
2003 Biggio G, Dazzi L, Follesa P. Neurosteroids alter GABA-A receptor subunit gene expression and the action of ethanol on mesocortical dopamine neurons Journal of Neurochemistry. 87: 23-23. DOI: 10.1046/J.1474-1644.2003.2170_20X  0.709
2002 Mascia MP, Biggio F, Mancuso L, Cabras S, Cocco PL, Gorini G, Manca A, Marra C, Purdy RH, Follesa P, Biggio G. Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, ganaxolone in cultured rat cerebellar granule cells. The Journal of Pharmacology and Experimental Therapeutics. 303: 1014-20. PMID 12438522 DOI: 10.1124/Jpet.102.040063  0.706
2002 Dazzi L, Serra M, Seu E, Cherchi G, Pisu MG, Purdy RH, Biggio G. Progesterone enhances ethanol-induced modulation of mesocortical dopamine neurons: antagonism by finasteride. Journal of Neurochemistry. 83: 1103-9. PMID 12437581 DOI: 10.1046/J.1471-4159.2002.01218.X  0.384
2002 Asproni B, Pau A, Bitti M, Melosu M, Cerri R, Dazzi L, Seu E, Maciocco E, Sanna E, Busonero F, Talani G, Pusceddu L, Altomare C, Trapani G, Biggio G. Synthesis and pharmacological evaluation of 1-[(1,2-diphenyl-1H-4-imidazolyl)methyl]-4-phenylpiperazines with clozapine-like mixed activities at dopamine D(2), serotonin, and GABA(A) receptors. Journal of Medicinal Chemistry. 45: 4655-68. PMID 12361392 DOI: 10.1021/Jm020848T  0.57
2002 Sanna E, Busonero F, Talani G, Carta M, Massa F, Peis M, Maciocco E, Biggio G. Comparison of the effects of zaleplon, zolpidem, and triazolam at various GABA(A) receptor subtypes. European Journal of Pharmacology. 451: 103-10. PMID 12231378 DOI: 10.1016/S0014-2999(02)02191-X  0.673
2002 Serra M, Pisul MG, Dazzi L, Purdy RH, Biggio G. Prevention of the stress-induced increase in the concentration of neuroactive steroids in rat brain by long-term administration of mirtazapine but not of fluoxetine. Journal of Psychopharmacology (Oxford, England). 16: 133-8. PMID 12095071 DOI: 10.1177/026988110201600203  0.322
2002 Dazzi L, Vignone V, Seu E, Ladu S, Vacca G, Biggio G. Inhibition by venlafaxine of the increase in norepinephrine output in rat prefrontal cortex elicited by acute stress or by the anxiogenic drug FG 7142. Journal of Psychopharmacology (Oxford, England). 16: 125-31. PMID 12095070 DOI: 10.1177/026988110201600202  0.375
2002 Trapani G, Dazzi L, Pisu MG, Reho A, Seu E, Biggio G. A rapid method for obtaining finasteride, a 5alpha-reductase inhibitor, from commercial tablets. Brain Research. Brain Research Protocols. 9: 130-4. PMID 12034332 DOI: 10.1016/S1385-299X(02)00146-0  0.313
2002 Dazzi L, Serra M, Vacca G, Ladu S, Latrofa A, Trapani G, Biggio G. Depletion of cortical allopregnanolone potentiates stress-induced increase in cortical dopamine output. Brain Research. 932: 135-9. PMID 11911871 DOI: 10.1016/S0006-8993(02)02290-4  0.329
2002 Follesa P, Porcu P, Sogliano C, Cinus M, Biggio F, Mancuso L, Mostallino MC, Paoletti AM, Purdy RH, Biggio G, Concas A. Changes in GABAA receptor gamma 2 subunit gene expression induced by long-term administration of oral contraceptives in rats. Neuropharmacology. 42: 325-36. PMID 11897111 DOI: 10.1016/S0028-3908(01)00187-3  0.729
2002 Follesa P, Mancuso L, Biggio F, Cagetti E, Franco M, Trapani G, Biggio G. Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, zaleplon or zolpidem. Neuropharmacology. 42: 191-8. PMID 11804615 DOI: 10.1016/S0028-3908(01)00167-8  0.686
2002 Dazzi L, Ladu S, Spiga F, Vacca G, Rivano A, Pira L, Biggio G. Chronic treatment with imipramine or mirtazapine antagonizes stress- and FG7142-induced increase in cortical norepinephrine output in freely moving rats. Synapse (New York, N.Y.). 43: 70-7. PMID 11746735 DOI: 10.1002/Syn.10024  0.396
2001 Pierobon P, Minei R, Porcu P, Sogliano C, Tino A, Marino G, Biggio G, Concas A. Putative glycine receptors in Hydra: a biochemical and behavioural study. The European Journal of Neuroscience. 14: 1659-66. PMID 11860460 DOI: 10.1046/J.0953-816X.2001.01792.X  0.424
2001 Follesa P, Concas A, Porcu P, Sanna E, Serra M, Mostallino MC, Purdy RH, Biggio G. Role of allopregnanolone in regulation of GABA(A) receptor plasticity during long-term exposure to and withdrawal from progesterone. Brain Research. Brain Research Reviews. 37: 81-90. PMID 11744076 DOI: 10.1016/S0165-0173(01)00125-4  0.79
2001 Pisu MG, Papi G, Porcu P, Trapani G, Latrofa A, Biggio G, Serra M. Binding of [3H]CB 34, a selective ligand for peripheral benzodiazepine receptors, to rat brain membranes. European Journal of Pharmacology. 432: 129-34. PMID 11740947 DOI: 10.1016/S0014-2999(01)01478-9  0.388
2001 Serra M, Pisu MG, Muggironi M, Parodo V, Papi G, Sari R, Dazzi L, Spiga F, Purdy RH, Biggio G. Opposite effects of short- versus long-term administration of fluoxetine on the concentrations of neuroactive steroids in rat plasma and brain. Psychopharmacology. 158: 48-54. PMID 11685383 DOI: 10.1007/S002130100853  0.355
2001 Ferrara G, Serra M, Zammaretti F, Pisu MG, Panzica GC, Biggio G, Eva C. Increased expression of the neuropeptide Y receptor Y(1) gene in the medial amygdala of transgenic mice induced by long-term treatment with progesterone or allopregnanolone. Journal of Neurochemistry. 79: 417-25. PMID 11677270 DOI: 10.1046/J.1471-4159.2001.00559.X  0.439
2001 Biggio G, Follesa P, Sanna E, Purdy RH, Concas A. GABAA-receptor plasticity during long-term exposure to and withdrawal from progesterone. International Review of Neurobiology. 46: 207-41. PMID 11599301 DOI: 10.1016/S0074-7742(01)46064-8  0.759
2001 Dazzi L, Serra M, Spiga F, Pisu MG, Jentsch JD, Biggio G. Prevention of the stress-induced increase in frontal cortical dopamine efflux of freely moving rats by long-term treatment with antidepressant drugs. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 11: 343-9. PMID 11597820 DOI: 10.1016/S0924-977X(01)00105-5  0.342
2001 Barbaccia ML, Affricano D, Purdy RH, Maciocco E, Spiga F, Biggio G. Clozapine, but not haloperidol, increases brain concentrations of neuroactive steroids in the rat. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 489-97. PMID 11557162 DOI: 10.1016/S0893-133X(01)00254-8  0.461
2001 Dazzi L, Vacca G, Ladu S, Pisu MG, Serra M, Biggio G. Long-term treatment with antidepressant drugs reduces the sensitivity of cortical cholinergic neurons to the activating actions of stress and the anxiogenic drug FG 7142. Neuropharmacology. 41: 229-37. PMID 11489459 DOI: 10.1016/S0028-3908(01)00064-8  0.326
2001 Follesa P, Cagetti E, Mancuso L, Biggio F, Manca A, Maciocco E, Massa F, Desole MS, Carta M, Busonero F, Sanna E, Biggio G. Increase in expression of the GABA(A) receptor alpha(4) subunit gene induced by withdrawal of, but not by long-term treatment with, benzodiazepine full or partial agonists. Brain Research. Molecular Brain Research. 92: 138-48. PMID 11483250 DOI: 10.1016/S0169-328X(01)00164-4  0.781
2001 Savini L, Chiasserini L, Pellerano C, Biggio G, Maciocco E, Serra M, Cinone N, Carrieri A, Altomare C, Carotti A. High affinity central benzodiazepine receptor ligands. Part 2: quantitative structure-activity relationships and comparative molecular field analysis of pyrazolo[4,3-c]quinolin-3-ones. Bioorganic & Medicinal Chemistry. 9: 431-44. PMID 11249135 DOI: 10.1016/S0968-0896(00)00262-5  0.33
2001 Dazzi L, Spiga F, Pira L, Ladu S, Vacca G, Rivano A, Jentsch JD, Biggio G. Inhibition of stress- or anxiogenic-drug-induced increases in dopamine release in the rat prefrontal cortex by long-term treatment with antidepressant drugs. Journal of Neurochemistry. 76: 1212-20. PMID 11181840 DOI: 10.1046/J.1471-4159.2001.00148.X  0.336
2001 Latrofa A, Trapani G, Franco M, Harris MJ, Serra M, Biggio G, Liso G. Synthesis of the [3H] labelled potent and selective peripheral benzodiazepine receptor ligand CB 34 Journal of Labelled Compounds and Radiopharmaceuticals. 44: 521-528. DOI: 10.1002/Jlcr.481  0.312
2000 Follesa P, Cagetti E, Porta S, Espositoto G, Biggio G. Pivagabine-induced increases in the abundance of CRF mRNA in the cerebral cortex and hypothalamus of rats. Brain Research. Molecular Brain Research. 84: 52-7. PMID 11113531 DOI: 10.1016/S0169-328X(00)00209-6  0.653
2000 Serra M, Littera M, Pisu MG, Muggironi M, Purdy RH, Biggio G. Steroidogenesis in rat brain induced by short- and long-term administration of carbamazepine. Neuropharmacology. 39: 2448-56. PMID 10974329 DOI: 10.1016/S0028-3908(00)00086-1  0.404
2000 Serra M, Pisu MG, Littera M, Papi G, Sanna E, Tuveri F, Usala L, Purdy RH, Biggio G. Social isolation-induced decreases in both the abundance of neuroactive steroids and GABA(A) receptor function in rat brain. Journal of Neurochemistry. 75: 732-40. PMID 10899949 DOI: 10.1046/J.1471-4159.2000.0750732.X  0.674
2000 Follesa P, Serra M, Cagetti E, Pisu MG, Porta S, Floris S, Massa F, Sanna E, Biggio G. Allopregnanolone synthesis in cerebellar granule cells: roles in regulation of GABA(A) receptor expression and function during progesterone treatment and withdrawal. Molecular Pharmacology. 57: 1262-70. PMID 10825399  0.775
2000 Trapani G, Altomare C, Liso G, Sanna E, Biggio G. Propofol in anesthesia. Mechanism of action, structure-activity relationships, and drug delivery. Current Medicinal Chemistry. 7: 249-71. PMID 10637364 DOI: 10.2174/0929867003375335  0.608
1999 Trapani G, Franco M, Latrofa A, Ricciardi L, Carotti A, Serra M, Sanna E, Biggio G, Liso G. Novel 2-phenylimidazo[1,2-a]pyridine derivatives as potent and selective ligands for peripheral benzodiazepine receptors: synthesis, binding affinity, and in vivo studies. Journal of Medicinal Chemistry. 42: 3934-41. PMID 10508441 DOI: 10.1021/Jm991035G  0.595
1999 Concas A, Follesa P, Barbaccia ML, Purdy RH, Biggio G. Physiological modulation of GABA(A) receptor plasticity by progesterone metabolites. European Journal of Pharmacology. 375: 225-35. PMID 10443579 DOI: 10.1016/S0014-2999(99)00232-0  0.696
1999 Serra M, Dazzi L, Caddeo M, Floris C, Biggio G. Reversal by flunarizine of the decrease in hippocampal acetylcholine release in pentylenetetrazole-kindled rats. Biochemical Pharmacology. 58: 145-9. PMID 10403527 DOI: 10.1016/S0006-2952(99)00068-4  0.375
1999 Follesa P, Tarantino A, Floris S, Mallei A, Porta S, Tuligi G, Cagetti E, Caddeo M, Mura A, Serra M, Biggio G. Changes in the gene expression of GABAA receptor subunit mRNAs in the septum of rats subjected to pentylenetetrazol-induced kindling. Brain Research. Molecular Brain Research. 70: 1-8. PMID 10381537 DOI: 10.1016/S0169-328X(99)00118-7  0.698
1999 Serra M, Madau P, Chessa MF, Caddeo M, Sanna E, Trapani G, Franco M, Liso G, Purdy RH, Barbaccia ML, Biggio G. 2-Phenyl-imidazo[1,2-a]pyridine derivatives as ligands for peripheral benzodiazepine receptors: stimulation of neurosteroid synthesis and anticonflict action in rats. British Journal of Pharmacology. 127: 177-87. PMID 10369471 DOI: 10.1038/Sj.Bjp.0702530  0.657
1999 Sanna E, Motzo C, Usala M, Serra M, Dazzi L, Maciocco E, Trapani G, Latrofa A, Liso G, Biggio G. Characterization of the electrophysiological and pharmacological effects of 4-iodo-2,6-diisopropylphenol, a propofol analogue devoid of sedative-anaesthetic properties. British Journal of Pharmacology. 126: 1444-54. PMID 10217539 DOI: 10.1038/Sj.Bjp.0702449  0.677
1999 Serra M, Concas A, Mostallino MC, Chessa MF, Stomati M, Petraglia F, Genazzani AR, Biggio G. Antagonism by pivagabine of stress-induced changes in GABAA receptor function and corticotropin-releasing factor concentrations in rat brain. Psychoneuroendocrinology. 24: 269-84. PMID 10101733 DOI: 10.1016/S0306-4530(98)00049-3  0.422
1999 Sanna E, Pau D, Tuveri F, Massa F, Maciocco E, Acquas C, Floris C, Fontana SN, Maira G, Biggio G. Molecular and neurochemical evaluation of the effects of etizolam on GABAA receptors under normal and stress conditions. Arzneimittel-Forschung. 49: 88-95. PMID 10083975 DOI: 10.1055/S-0031-1300366  0.669
1999 Follesa P, Mallei A, Floris S, Mostallino MC, Sanna E, Biggio G. Increased abundance of GABAA receptor subunit mRNAs in the brain of Long-Evans Cinnamon rats, an animal model of Wilson's disease. Brain Research. Molecular Brain Research. 63: 268-75. PMID 9878778 DOI: 10.1016/S0169-328X(98)00290-3  0.747
1998 Barbaccia ML, Concas A, Serra M, Biggio G. Stress and neurosteroids in adult and aged rats. Experimental Gerontology. 33: 697-712. PMID 9951617 DOI: 10.1016/S0531-5565(98)00042-4  0.476
1998 Concas A, Mostallino MC, Porcu P, Follesa P, Barbaccia ML, Trabucchi M, Purdy RH, Grisenti P, Biggio G. Role of brain allopregnanolone in the plasticity of gamma-aminobutyric acid type A receptor in rat brain during pregnancy and after delivery. Proceedings of the National Academy of Sciences of the United States of America. 95: 13284-9. PMID 9789080 DOI: 10.1073/Pnas.95.22.13284  0.684
1998 Follesa P, Floris S, Tuligi G, Mostallino MC, Concas A, Biggio G. Molecular and functional adaptation of the GABA(A) receptor complex during pregnancy and after delivery in the rat brain. The European Journal of Neuroscience. 10: 2905-12. PMID 9758160 DOI: 10.1111/J.1460-9568.1998.00300.X  0.692
1998 Concas A, Pierobon P, Mostallino MC, Porcu P, Marino G, Minei R, Biggio G. Modulation of gamma-aminobutyric acid (GABA) receptors and the feeding response by neurosteroids in Hydra vulgaris. Neuroscience. 85: 979-88. PMID 9639289 DOI: 10.1016/S0306-4522(97)00515-0  0.49
1998 Sanna E, Motzo C, Usala M, Pau D, Cagetti E, Biggio G. Functional changes in rat nigral GABA(A) receptors induced by degeneration of the striatonigral GABAergic pathway: an electrophysiological study of receptors incorporated into Xenopus oocytes. Journal of Neurochemistry. 70: 2539-44. PMID 9603220 DOI: 10.1046/J.1471-4159.1998.70062539.X  0.678
1998 Trapani G, Latrofa A, Franco M, Altomare C, Sanna E, Usala M, Biggio G, Liso G. Propofol analogues. Synthesis, relationships between structure and affinity at GABAA receptor in rat brain, and differential electrophysiological profile at recombinant human GABAA receptors. Journal of Medicinal Chemistry. 41: 1846-54. PMID 9599235 DOI: 10.1021/Jm970681H  0.668
1998 Savini L, Massarelli P, Nencini C, Pellerano C, Biggio G, Maciocco A, Tuligi G, Carrieri A, Cinone N, Carotti A. High affinity central benzodiazepine receptor ligands: synthesis and structure-activity relationship studies of a new series of pyrazolo[4,3-c]quinolin-3-ones. Bioorganic & Medicinal Chemistry. 6: 389-99. PMID 9597183 DOI: 10.1016/S0968-0896(97)10039-6  0.33
1998 Imperato A, Dazzi L, Carta G, Colombo G, Biggio G. Rapid increase in basal acetylcholine release in the hippocampus of freely moving rats induced by withdrawal from long-term ethanol intoxication. Brain Research. 784: 347-50. PMID 9518686 DOI: 10.1016/S0006-8993(97)01399-1  0.354
1998 Ghiani CA, Dazzi L, Maciocco E, Flore G, Maira G, Biggio G. Antagonism by abecarnil of enhanced acetylcholine release in the rat brain during anticipation but not consumption of food. Pharmacology, Biochemistry, and Behavior. 59: 657-62. PMID 9512068 DOI: 10.1016/S0091-3057(97)00426-7  0.355
1998 Sanna E, Pau D, Tuveri F, Massa F, Maciocco E, Piras C, Canu B, Biggio G. Caratterizzazione neurochimica ed elettrofisiologica degli effeti dell'etizolam su recettori GABAA neuronali di ratto e ricombinanti umani Giornale Di Neuropsicofarmacologia. 20: 115-121.  0.423
1997 Trapani G, Franco M, Ricciardi L, Latrofa A, Genchi G, Sanna E, Tuveri F, Cagetti E, Biggio G, Liso G. Synthesis and binding affinity of 2-phenylimidazo[1,2-alpha]pyridine derivatives for both central and peripheral benzodiazepine receptors. A new series of high-affinity and selective ligands for the peripheral type. Journal of Medicinal Chemistry. 40: 3109-18. PMID 9301675 DOI: 10.1021/Jm970112+  0.537
1997 Dazzi L, Serra M, Porceddu ML, Sanna A, Chessa MF, Biggio G. Enhancement of basal and pentylenetetrazol (PTZ)-stimulated dopamine release in the brain of freely moving rats by PTZ-induced kindling. Synapse (New York, N.Y.). 26: 351-8. PMID 9215594 DOI: 10.1002/(Sici)1098-2396(199708)26:4<351::Aid-Syn3>3.0.Co;2-5  0.363
1997 Motzo C, Porceddu ML, Dazzi L, Sanna A, Serra M, Biggio G. Enhancement by flumazenil of dopamine release in the nucleus accumbens of rats repeatedly exposed to diazepam or imidazenil. Psychopharmacology. 131: 34-9. PMID 9181633 DOI: 10.1007/S002130050262  0.392
1997 Serra M, Cuccu R, Ghiani CA, Pisu MG, Murgia A, Biggio G. Antagonism of convulsions but failure to enhance GABA(A) receptor function by felbamate in mice tolerant to diazepam. Neurochemical Research. 22: 693-7. PMID 9178952 DOI: 10.1023/A:1027349909655  0.329
1997 Padiglia A, Medda R, Lorrai A, Biggio G, Sanna E, Floris G. Modulation of 6-hydroxydopamine oxidation by various proteins. Biochemical Pharmacology. 53: 1065-8. PMID 9175710 DOI: 10.1016/S0006-2952(96)00716-2  0.495
1997 Barbaccia ML, Roscetti G, Trabucchi M, Purdy RH, Mostallino MC, Concas A, Biggio G. The effects of inhibitors of GABAergic transmission and stress on brain and plasma allopregnanolone concentrations. British Journal of Pharmacology. 120: 1582-8. PMID 9113382 DOI: 10.1038/Sj.Bjp.0701046  0.453
1997 Serra M, Dazzi L, Pisu MG, Cagetti E, Biggio G. Reversal of a selective decrease in hippocampal acetylcholine release, but not of the persistence of kindling, after discontinuation of long-term pentylenetetrazol administration in rats. Brain Research. 751: 175-9. PMID 9098585 DOI: 10.1016/S0006-8993(97)00054-1  0.426
1997 Sanna E, Murgia A, Casula A, Biggio G. Differential subunit dependence of the actions of the general anesthetics alphaxalone and etomidate at gamma-aminobutyric acid type A receptors expressed in Xenopus laevis oocytes. Molecular Pharmacology. 51: 484-90. PMID 9058604  0.56
1997 Serra M, Dazzi L, Cagetti E, Chessa MF, Pisu MG, Sanna A, Biggio G. Effect of pentylenetetrazole-induced kindling on acetylcholine release in the hippocampus of freely moving rats. Journal of Neurochemistry. 68: 313-8. PMID 8978740  0.336
1997 Biggio G, Concas A, Barbaccia ML. Role of HPA axis in the modulation of brain and plasma neurosteroid content elicited by stress and benzodiazepine receptor ligands Biological Psychiatry. 42. DOI: 10.1016/S0006-3223(97)87203-4  0.351
1996 Sanna E, Murgia A, Casula A, Usala M, Maciocco E, Tuligi G, Biggio G. Direct activation of GABAA receptors by loreclezole, an anticonvulsant drug with selectivity for the beta-subunit. Neuropharmacology. 35: 1753-60. PMID 9076754 DOI: 10.1016/S0028-3908(96)00138-4  0.667
1996 Barbaccia ML, Roscetti G, Trabucchi M, Mostallino MC, Concas A, Purdy RH, Biggio G. Time-dependent changes in rat brain neuroactive steroid concentrations and GABAA receptor function after acute stress Neuroendocrinology. 63: 166-172. PMID 9053781 DOI: 10.1159/000126953  0.41
1996 Barbaccia ML, Roscetti G, Trabucchi M, Purdy RH, Mostallino MC, Perra C, Concas A, Biggio G. Isoniazid-induced inhibition of GABAergic transmission enhances neurosteroid content in the rat brain Neuropharmacology. 35: 1299-1305. PMID 9014145 DOI: 10.1016/S0028-3908(96)00067-6  0.367
1996 Dazzi L, Sanna A, Cagetti E, Concas A, Biggio G. Inhibition by the neurosteroid allopregnanolone of basal and stress-induced acetylcholine release in the brain of freely moving rats Brain Research. 710: 275-280. PMID 8963670 DOI: 10.1016/0006-8993(95)01478-0  0.405
1996 Sanna E, Motzo C, Murgia A, Amato F, Deserra T, Biggio G. Expression of native GABAA receptors in Xenopus oocytes injected with rat brain synaptosomes. Journal of Neurochemistry. 67: 2212-4. PMID 8863534 DOI: 10.1046/J.1471-4159.1996.67052212.X  0.647
1996 Concas A, Mascia MP, Cuccheddu T, Floris S, Mostallino MC, Perra C, Satta S, Biggio G. Chronic ethanol intoxication enhances [3H]CCPA binding and does not reduce A1 adenosine receptor function in rat cerebellum. Pharmacology, Biochemistry, and Behavior. 53: 249-55. PMID 8808128 DOI: 10.1016/0091-3057(95)00208-1  0.39
1996 Concas A, Mostallino MC, Perra C, Lener R, Roscetti G, Barbaccia ML, Purdy RH, Biggio G. Functional correlation between allopregnanolone and [35S]-TBPS binding in the brain of rats exposed to isoniazid, pentylenetetrazol or stress. British Journal of Pharmacology. 118: 839-46. PMID 8799552 DOI: 10.1111/J.1476-5381.1996.Tb15476.X  0.455
1996 Barbaccia ML, Roscetti G, Bolacchi F, Concas A, Mostallino MC, Purdy RH, Biggio G. Stress-induced increase in brain neuroactive steroids: antagonism by abecarnil. Pharmacology, Biochemistry, and Behavior. 54: 205-10. PMID 8728559 DOI: 10.1016/0091-3057(95)02133-7  0.374
1996 Ghiani CA, Tuligi G, Maciocco E, Serra M, Sanna E, Biggio G. Biochemical evaluations of the effects of loreclezole and propofol on the GABAA receptor in rat brain. Biochemical Pharmacology. 51: 1527-34. PMID 8630094 DOI: 10.1016/0006-2952(96)00094-9  0.65
1996 Serra M, Ghiani CA, Maciocco E, Pisu MG, Tuligi G, Porceddu ML, Biggio G. Failure of chronic treatment with abecarnil to induce contingent and noncontingent tolerance in pentylenetetrazol-kindled rats Epilepsia. 37: 332-335. PMID 8603637 DOI: 10.1111/J.1528-1157.1996.Tb00568.X  0.4
1996 Motzo C, Porceddu ML, Maira G, Flore G, Concas A, Dazzi L, Biggio G. Inhibition of basal and stress-induced dopamine release in the cerebral cortex and nucleus accumbens of freely moving rats by the neurosteroid allopregnanolone Journal of Psychopharmacology. 10: 266-272. DOI: 10.1177/026988119601000402  0.46
1996 Trapani G, Franco M, Latrofa A, Carotti A, Genchi G, Serra M, Biggio G, Liso G. Synthesis and benzodiazepine receptor binding of some imidazo- and pyrimido[2,1-b]benzothiazoles European Journal of Medicinal Chemistry. 31: 575-587. DOI: 10.1016/0223-5234(96)89553-5  0.371
1996 Serra M, Concas A, Biggio G. Failure of long-term administration of zopiclone and zolpidem to induce tolerance in mice Neuroscience Research Communications. 19: 169-178. DOI: 10.1002/(Sici)1520-6769(199611)19:3<169::Aid-Nrc177>3.0.Co;2-F  0.331
1996 Concas A, Mostallino MC, Perra C, Chisu F, Porcu P, Tosciri MA, Biggio G. Differential antagonism by the selective A1 adenosine receptor agonist CCPA of seizures induced by NMDA, kainic acid, and domoic acid Neuroscience Research Communications. 18: 9-18. DOI: 10.1002/(Sici)1520-6769(199601)18:1<9::Aid-Nrc135>3.0.Co;2-9  0.316
1995 Cuccheddu T, Floris S, Serra M, Porceddu ML, Sanna E, Biggio G. Proconflict effect of carbon dioxide inhalation in rats. Life Sciences. 56: PL321-4. PMID 8614250 DOI: 10.1016/0024-3205(95)00093-3  0.62
1995 Serra M, Ghiani CA, Motzo C, Porceddu ML, Biggio G. Antagonism of isoniazid-induced convulsions by abecarnil in mice tolerant to diazepam Pharmacology, Biochemistry and Behavior. 52: 249-254. PMID 8577786 DOI: 10.1016/0091-3057(94)00422-F  0.319
1995 Dazzi L, Motzo C, Maira G, Sanna A, Serra M, Biggio G. Enhancement of acetylcholine release by flumazenil in the hippocampus of rats chronically treated with diazepam but not with imidazenil or abecarnil Psychopharmacology. 121: 180-185. PMID 8545523 DOI: 10.1007/Bf02245628  0.41
1995 Pierobon P, Concas A, Santoro G, Marino G, Minei R, Pannaccione A, Mostallino MC, Biggio G. Biochemical and functional identification of GABA receptors in Hydra vulgaris Life Sciences. 56: 1485-1497. PMID 7752813 DOI: 10.1016/0024-3205(95)00111-I  0.449
1995 Dazzi L, Motzo C, Imperato A, Serra M, Gessa GL, Biggio G. Modulation of basal and stress-induced release of acetylcholine and dopamine in rat brain by abecarnil and imidazenil, two anxioselective gamma-aminobutyric acidA receptor modulators. The Journal of Pharmacology and Experimental Therapeutics. 273: 241-7. PMID 7714771  0.468
1995 Sanna E, Mascia MP, Klein RL, Whiting PJ, Biggio G, Harris RA. Actions of the general anesthetic propofol on recombinant human GABAA receptors: influence of receptor subunits. The Journal of Pharmacology and Experimental Therapeutics. 274: 353-60. PMID 7616420  0.621
1995 Motzo C, Dazzi L, Concas A, Biggio G. Intraseptal injection of caffeine enhances acetylcholine release in the hippocampus of freely moving rats: 29.2 Behavioural Pharmacology. 6: 144. DOI: 10.1097/00008877-199505001-00172  0.32
1995 Mostallino MC, Concas A, Perra C, Porcu P, Barbaccia ML, Biggio G. Intracerebroventricular injection of allopregnanolone enhances the function of the chioride channel coupled to GABAA receptors: 27.2 Behavioural Pharmacology. 6: 139. DOI: 10.1097/00008877-199505001-00165  0.321
1995 Sanna E, Casula A, Murgia A, Tuligi G, Maciocco E, Whiting PJ, Biggio G. Biochemical and electrophysiological evidence for the direct activation of GABAA receptors by loreclezole: comparison with propofol and diazepam Behavioural Pharmacology. 6: 112. DOI: 10.1097/00008877-199505001-00131  0.601
1995 Pannaccione A, Pierobon P, Concas A, Santoro G, Marino G, Minei R, Mostallino MC, Biggio G. Biochemical and functional identification of GABA receptors in Hydra vulgaris: 20.11 Behavioural Pharmacology. 6: 111. DOI: 10.1097/00008877-199505001-00130  0.452
1995 Ghiani CA, Tuligi G, Maciocco E, Serra M, Biggio G. Differential modulation of GABAA receptor by loreclezole and propofol, two selective ligands for ?? subunits: 20.5 Behavioural Pharmacology. 6: 105. DOI: 10.1097/00008877-199505001-00124  0.372
1995 Dazzi L, Motzo C, Maira G, Sanna A, Serra M, Biggio G. Changes in hippocampal acetylcholine release elicited by chronic administration of diazepam. abecarnil or imidazenil in freely moving rats: 10.2 Behavioural Pharmacology. 6: 52. DOI: 10.1097/00008877-199505001-00060  0.332
1995 Cignarella G, Barlocco D, Pocar D, Clerici F, Curzu MM, Gessa GL, Fadda F, Serra M, Biggio G. Synthesis and pharmacological evaluation of a new series of substituted benzoyl-γ-butyrolactone derivatives European Journal of Medicinal Chemistry. 30: 721-726. DOI: 10.1016/0223-5234(96)88290-0  0.513
1994 Imperato A, Dazzi L, Obinu MC, Gessa GL, Biggio G. The benzodiazepine receptor antagonist flumazenil increases acetylcholine release in rat hippocampus. Brain Research. 647: 167-71. PMID 8069701 DOI: 10.1016/0006-8993(94)91413-3  0.587
1994 Concas A, Santoro G, Mascia MP, Maciocco E, Dazzi L, Biggio G. Effects of propofol, pentobarbital and alphaxalone on t-[35S]butylbicyclophosphorothionate binding in rat cerebral cortex. European Journal of Pharmacology. 267: 207-13. PMID 8050480 DOI: 10.1016/0922-4106(94)90172-4  0.416
1994 Ghiani CA, Serra M, Motzo C, Giusti P, Cuccheddu T, Porceddu ML, Biggio G. Chronic administration of an anticonvulsant dose of imidazenil fails to induce tolerance of GABAA receptor function in mice. European Journal of Pharmacology. 254: 299-302. PMID 8013567 DOI: 10.1016/0014-2999(94)90470-7  0.407
1994 Imperato A, Dazzi L, Serra M, Gessa GL, Biggio G. Differential effects of abecarnil on basal release of acetylcholine and dopamine in the rat brain. European Journal of Pharmacology. 261: 205-8. PMID 8001645 DOI: 10.1016/0014-2999(94)90320-4  0.54
1994 Serra M, Ghiani CA, Motzo C, Porceddu ML, Biggio G. Long-term treatment with abecarnil fails to induce tolerance in mice. European Journal of Pharmacology. 259: 1-6. PMID 7957586 DOI: 10.1016/0014-2999(94)90149-X  0.319
1994 Serra M, Ghiani CA, Foddi MC, Motzo C, Biggio G. NMDA receptor function is enhanced in the hippocampus of aged rats. Neurochemical Research. 19: 483-7. PMID 7915012 DOI: 10.1007/Bf00967328  0.4
1994 Serra M, Ghiani CA, Spano S, Biggio G. Felbamate antagonizes isoniazid- and FG 7142-induced reduction of GABAA receptor function in mouse brain. European Journal of Pharmacology. 265: 185-8. PMID 7875235 DOI: 10.1016/0014-2999(94)90431-6  0.388
1994 Concas A, Serra M, Santoro G, Maciocco E, Cuccheddu T, Biggio G. The effect of cyclopyrrolones on GABAA receptor function is different from that of benzodiazepines. Naunyn-Schmiedebergs Archives of Pharmacology. 350: 294-300. PMID 7824046 DOI: 10.1007/Bf00175035  0.44
1994 Barbaccia ML, Roscetti G, Trabucchi M, Cuccheddu T, Concas A, Biggio G. Neurosteroids in the brain of handling-habituated and naive rats: effect of CO2 inhalation European Journal of Pharmacology. 261: 317-320. PMID 7813554 DOI: 10.1016/0014-2999(94)90123-6  0.364
1994 Concas A, Cuccheddu T, Floris S, Mascia MP, Biggio G. 2-Chloro-N6-cyclopentyladenosine (CCPA), an adenosine A1 receptor agonist, suppresses ethanol withdrawal syndrome in rats. Alcohol and Alcoholism. 29: 261-264. DOI: 10.1093/Oxfordjournals.Alcalc.A045532  0.37
1994 Trapani G, Franco M, Latrofa A, Genchi G, Brigiani GS, Mazzoccoli M, Persichella M, Serra M, Biggio G, Liso G. Synthesis and anticonvulsant activity of some 1,2,3,3a-tetrahydropyrrolo[2,1-b]benzothiazol-1-ones and pyrrolo[2,1-b]thiazole analogues European Journal of Medicinal Chemistry. 29: 197-204. DOI: 10.1016/0223-5234(94)90038-8  0.337
1993 Imperato A, Dazzi L, Obinu MC, Gessa GL, Biggio G. Inhibition of hippocampal acetylcholine release by benzodiazepines: antagonism by flumazenil. European Journal of Pharmacology. 238: 135-7. PMID 8405078 DOI: 10.1016/0014-2999(93)90518-M  0.574
1993 Sanna E, Serra M, Cossu A, Colombo G, Follesa P, Cuccheddu T, Concas A, Biggio G. Chronic ethanol intoxication induces differential effects on GABAA and NMDA receptor function in the rat brain. Alcoholism, Clinical and Experimental Research. 17: 115-23. PMID 8383922 DOI: 10.1111/J.1530-0277.1993.Tb00735.X  0.758
1993 Bernardi G, Biggio G, Erspamer V, Fratta W, Gessa GL, Mantegazza P, Moroni F, Pepeu G. Fidia and neuroscience. Nature. 366: 399. PMID 8247140 DOI: 10.1038/366399C0  0.315
1993 Serra M, Ghiani CA, Motzo C, Biggio G. Pharmacological evidence for full agonist activity of abecarnil at certain GABAA receptors. Psychopharmacology Series. 11: 62-78. PMID 7908434 DOI: 10.1007/978-3-642-78451-4_6  0.397
1993 Concas A, Sanna E, Cuccheddu T, Mascia MP, Santoro G, Maciocco E, Biggio G. Carbon dioxide inhalation, stress and anxiogenic drugs reduce the function of GABAA receptor complex in the rat brain. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 17: 651-61. PMID 7689736 DOI: 10.1016/0278-5846(93)90012-H  0.573
1993 Biggio G, Serra M, Ghiani CA, Giusti P. Isoniazid-induced inhibition of GABAergic transmission enhances the efficacy of imidazenil, a new partial agonist of benzodiazepine receptors European Neuropsychopharmacology. 3: 268-269. DOI: 10.1016/0924-977X(93)90065-T  0.456
1992 Biggio G, Cibin M, Diana M, Fadda F, Ferrara SD, Gallimberti L, Gessa GL, Mereu GP, Rossetti ZL, Serra M. Suppression of voluntary alcohol intake in rats and alcoholics by gamma-hydroxybutyric acid: a non-GABAergic mechanism. Advances in Biochemical Psychopharmacology. 47: 281-8. PMID 1509925  0.384
1992 Sanna E, Serra M, Cossu A, Colombo G, Follesa P, Biggio G. GABAA and NMDA receptor function during chronic administration of ethanol. Advances in Biochemical Psychopharmacology. 47: 317-24. PMID 1380758  0.714
1992 Giorgi O, Pibiri MG, Toso RD, Toffano G, Biggio G. Differential turnover rates of D1 dopamine receptors in the brain and retina of adult and senescent rats. Neurochemistry International. 20: 171-173. PMID 1365420 DOI: 10.1016/0197-0186(92)90233-H  0.391
1992 Serra M, Foddi MC, Ghiani CA, Melis MA, Motzo C, Concas A, Sanna E, Biggio G. Pharmacology of gamma-aminobutyric acidA receptor complex after the in vivo administration of the anxioselective and anticonvulsant beta-carboline derivative abecarnil. The Journal of Pharmacology and Experimental Therapeutics. 263: 1360-8. PMID 1361574  0.597
1992 Sanna E, Cuccheddu T, Serra M, Concas A, Biggio G. Carbon dioxide inhalation reduces the function of GABAA receptors in the rat brain. European Journal of Pharmacology. 216: 457-8. PMID 1330586 DOI: 10.1016/0014-2999(92)90447-C  0.659
1992 Concas A, Serra M, Sanna E, Pepitoni S, Mascia MP, Biggio G. Involvement of GABA-dependent chloride channel in the action of anticonvulsant and convulsant drugs. Epilepsy Research. Supplement. 8: 77-85. PMID 1329830  0.535
1992 Concas A, Santoro G, Mascia MP, Serra M, Sanna E, Biggio G. The action of the general anesthetic propofol on GABAA receptors. Advances in Biochemical Psychopharmacology. 47: 349-63. PMID 1324582  0.562
1991 Serra M, Sanna E, Concas A, Foddi C, Biggio G. Foot-shock stress enhances the increase of [35S]TBPS binding in the rat cerebral cortex and the convulsions induced by isoniazid. Neurochemical Research. 16: 17-22. PMID 2052136 DOI: 10.1007/Bf00965822  0.582
1991 Giorgi O, Pibiri MG, Ongini E, Trampus M, Biggio G. The neutral endopeptidase-24.11 (enkephalinase) inhibitor, SCH 32615, increases dopamine metabolism in the nucleus accumbens of the rat European Journal of Pharmacology. 196: 137-142. PMID 1874283 DOI: 10.1016/0014-2999(91)90419-Q  0.354
1991 Concas A, Santoro G, Serra M, Sanna E, Biggio G. Neurochemical action of the general anaesthetic propofol on the chloride ion channel coupled with GABAA receptors. Brain Research. 542: 225-32. PMID 1851453 DOI: 10.1016/0006-8993(91)91571-H  0.656
1991 Serra M, Sanna E, Foddi C, Concas A, Biggio G. Failure of gamma-hydroxybutyrate to alter the function of the GABAA receptor complex in the rat cerebral cortex. Psychopharmacology. 104: 351-5. PMID 1718012 DOI: 10.1007/Bf02246035  0.649
1991 Sanna E, Concas A, Serra M, Santoro G, Biggio G. Ex vivo binding of t-[35S )butylbicyclophosphorothionate: a biochemical tool to study the pharmacology of ethanol at the gamma-aminobutyric acid-coupled chloride channel. The Journal of Pharmacology and Experimental Therapeutics. 256: 922-8. PMID 1706433  0.569
1991 Giorgi O, Pibiri MG, Biggio G. Differential turnover rates of D1 dopamine receptors in the retina and in distinct areas of the rat brain Journal of Neurochemistry. 57: 754-759. PMID 1677675 DOI: 10.1111/J.1471-4159.1991.Tb08216.X  0.373
1991 Biggio G, Sanna E, Serra M, Serra GP, Concas A. "In vivo" inhibition of GABAergic transmission increases 35S-TBPS binding in the rat brain. Advances in Experimental Medicine and Biology. 287: 391-404. PMID 1662012 DOI: 10.1007/978-1-4684-5907-4_34  0.575
1991 Peduto VA, Concas A, Santoro G, Biggio G, Gessa GL. Biochemical and electrophysiologic evidence that propofol enhances GABAergic transmission in the rat brain. Anesthesiology. 75: 1000-9. PMID 1660227  0.482
1991 Concas A, Mascia MP, Sanna E, Santoro G, Serra M, Biggio G. "In vivo" administration of valproate decreases t-[35S]butylbicyclophosphorothionate binding in the rat brain. Naunyn-Schmiedeberg's Archives of Pharmacology. 343: 296-300. PMID 1650919 DOI: 10.1007/Bf00251129  0.607
1991 Biggio G, Costa E. Gaba and Benzodiazepine Receptor Subtypes International Clinical Psychopharmacology. 6: 127. DOI: 10.1097/00004850-199100620-00011  0.46
1991 Serra M, Foddi MC, Ghiani CA, Biggio G. Upregulation of [3H]MK-801 binding in the rat cerebellar cortex induced by degeneration of climbing fibers European Neuropsychopharmacology. 1: 414. DOI: 10.1016/0924-977X(91)90608-W  0.31
1990 Concas A, Sanna E, Mascia MP, Serra M, Biggio G. Diazepam enhances bicuculline-induced increase of t-[35S]butylbicyclophosphorothionate binding in unwashed membrane preparations from rat cerebral cortex. Neuroscience Letters. 112: 87-91. PMID 2385368 DOI: 10.1016/0304-3940(90)90327-6  0.637
1990 Giorgi O, Porceddu ML, Pepitoni S, Serra GP, Toffano G, Biggio G. Differential effect of aging on 3H-SCH 23390 binding sites in the retina and in distinct areas of the rat brain. Journal of Neural Transmission. 82: 157-166. PMID 2248731 DOI: 10.1007/Bf01272759  0.379
1990 Porceddu ML, Montis GD, Pepitoni S, Toffano G, Biggio G. Failure of dark adaptation to upregulate D-1 dopamine receptors in retina of senescent rats Neurobiology of Aging. 11: 105-109. PMID 2190105 DOI: 10.1016/0197-4580(90)90042-X  0.374
1990 Concas A, Santoro G, Mascia MP, Serra M, Sanna E, Biggio G. The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex. Journal of Neurochemistry. 55: 2135-8. PMID 2172469 DOI: 10.1111/J.1471-4159.1990.Tb05807.X  0.6
1990 Giorgi O, Biggio G. Selective unilateral inactivation of striatal D1 and D2 dopamine receptor subtypes by EEDQ: turning behavior elicited by D2 dopamine receptor agonists. Brain Research. 533: 53-59. PMID 1982234 DOI: 10.1016/0006-8993(90)91794-H  0.356
1990 Biggio G, Concas A, Corda MG, Giorgi O, Sanna E, Serra M. GABAergic and dopaminergic transmission in the rat cerebral cortex: effect of stress, anxiolytic and anxiogenic drugs. Pharmacology & Therapeutics. 48: 121-42. PMID 1981393 DOI: 10.1016/0163-7258(90)90077-F  0.675
1990 Mereu G, Carcangiu G, Concas A, Passino N, Biggio G. Reduction of reticulata neuronal activity by zolpidem and alpidem, two imidazopyridines with high affinity for type I benzodiazepine receptors. European Journal of Pharmacology. 179: 339-345. PMID 1973107 DOI: 10.1016/0014-2999(90)90174-5  0.355
1990 Giorgi O, Biggio G. Unilateral inactivation of dopamine receptors after intrastriatal injection of N-ethoxy-carbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ): a novel rotational model to investigate dopamine receptor interactions. Pharmacology, Biochemistry and Behavior. 35: 877-884. PMID 1971721 DOI: 10.1016/0091-3057(90)90374-Q  0.381
1990 Sanna E, Concas A, Serra M, Biggio G. Enhancement of GABA-dependent chloride channel by "in vivo" administration of ethanol. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 22: 91-2. PMID 1704623 DOI: 10.1016/1043-6618(90)90823-V  0.557
1990 Corda M, Giorgi O, Longoni B, Orlandi M, Biggio G. Decrease in the Function of the γ-Aminobutyric Acid-Coupled Chloride Channel Produced by the Repeated Administration of Pentylenetetrazol to Rats Journal of Neurochemistry. 55: 1216-1221. PMID 1697889 DOI: 10.1111/J.1471-4159.1990.Tb03127.X  0.438
1990 Sanna E, Concas A, Serra M, Biggio G. In vivo administration of ethanol enhances the function of the gamma-aminobutyric acid-dependent chloride channel in the rat cerebral cortex. Journal of Neurochemistry. 54: 696-8. PMID 1688923 DOI: 10.1111/J.1471-4159.1990.Tb01926.X  0.628
1989 Piccolino M, Demontis G, Witkovsky P, Strettoi E, Cappagli GC, Porceddu ML, De Montis MG, Pepitoni S, Biggio G, Meller E, Bohmaker K. Involvement of D1 and D2 Dopamine Receptors in the Control of Horizontal Cell Electrical Coupling in the Turtle Retina. The European Journal of Neuroscience. 1: 247-257. PMID 12106155 DOI: 10.1111/J.1460-9568.1989.Tb00792.X  0.311
1989 Corda M, Giorgi O, Longoni B, Ongini E, Pesce G, Cruciani R, Biggio G. Functional coupling of GABAA receptors and benzodiazepine recognition site subtypes in the spinal cord of the rat. European Journal of Pharmacology. 169: 205-213. PMID 2553447 DOI: 10.1016/0014-2999(89)90017-4  0.363
1989 Sanna E, Serra M, Pepitoni S, Biggio G. Dramatic increase in nigral t-[35S]butylbicyclophosphorothionate binding sites elicited by the degeneration of the striato-nigral GABAergic pathway: reversal by diazepam. Brain Research. 501: 144-9. PMID 2553212 DOI: 10.1016/0006-8993(89)91035-4  0.63
1989 Serra M, Sanna E, Biggio G. Isoniazid, an inhibitor of GABAergic transmission, enhances [35S]TBPS binding in rat cerebral cortex. European Journal of Pharmacology. 164: 385-8. PMID 2547641 DOI: 10.1016/0014-2999(89)90484-6  0.626
1989 Giorgi O, Corda MG, Fernandez A, Biggio G. The β-carboline derivatives ZK 93426 and FG 7142 fail to precipitate abstinence signs in diazepam-dependent cats Pharmacology, Biochemistry and Behavior. 32: 671-675. PMID 2544903 DOI: 10.1016/0091-3057(89)90016-6  0.31
1989 Biggio G, Concas A, Corda MG, Serra M. Enhancement of GABAergic transmission by zolpidem, an imidazopyridine with preferential affinity for type I benzodiazepine receptors. European Journal of Pharmacology. 161: 173-180. PMID 2542044 DOI: 10.1016/0014-2999(89)90840-6  0.46
1989 Corda MG, Longoni B, Cau A, Paci S, Salvadori S, Laudani U, Biggio G. Distribution and Pharmacological Properties of the GABAA/ Benzodiazepine/Chloride Ionophore Receptor Complex in the Brain of the Fish Anguilla anguilla Journal of Neurochemistry. 52: 1025-1034. PMID 2538558 DOI: 10.1111/J.1471-4159.1989.Tb01843.X  0.461
1989 Corda M, Giorgi O, Longoni B, Biggio G. Ro 15-4513, a partial inverse agonist for benzodiazepine recognition sites, has proconflict and proconvulsant effects in the rat European Journal of Pharmacology. 159: 233-239. PMID 2537736 DOI: 10.1016/0014-2999(89)90153-2  0.424
1988 Malatynska E, Serra M, Ikeda M, Biggio G, Yamamura HI. Modulation of GABA-stimulated chloride influx by beta-carbolines in rat brain membrane vesicles. Brain Research. 443: 395-7. PMID 3359279 DOI: 10.1016/0006-8993(88)91640-X  0.385
1988 Giorgi O, Corda MG, Biggio G. Ro 15-4513, like anxiogenic β-carbolines, increases dopamine metabolism in the prefrontal cortex of the rat European Journal of Pharmacology. 156: 71-75. PMID 3208840 DOI: 10.1016/0014-2999(88)90148-3  0.331
1988 Corda MG, Giorgi O, Longoni BM, Ongini E, Montaldo S, Paribello F, Biggio G. Characterization of 3H-2-oxo-quazepam binding in the human brain. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 12: 701-712. PMID 2906158 DOI: 10.1016/0278-5846(88)90015-2  0.342
1988 Concas A, Serra M, Atsoggiu T, Biggio G. Foot‐Shock Stress and Anxiogenic β‐Carbolines Increase t‐[35S]Butylbicyclophosphorothionate Binding in the Rat Cerebral Cortex, an Effect Opposite to Anxiolytics and γ‐Aminobutyric Acid Mimetics Journal of Neurochemistry. 51: 1868-1876. PMID 2903223 DOI: 10.1111/J.1471-4159.1988.Tb01170.X  0.479
1988 Corda M, Giorgi O, Longoni B, Ongini E, Montaldo S, Biggio G. Preferential affinity of 3H-2-oxo-quazepam for type I benzodiazepine recognition sites in the human brain. Life Sciences. 42: 189-197. PMID 2892107 DOI: 10.1016/0024-3205(88)90682-0  0.302
1988 Longoni B, Corda MG, Biggio G. Functional interaction between GABA receptors and type I benzo-diazepine recognition sites in the spinal cord of the rat Pharmacological Research Communications. 20: 1089-1090. PMID 2850584 DOI: 10.1016/S0031-6989(88)80740-9  0.383
1988 Giorgi O, Corda MG, Fernández A, Biggio G. The abstinence syndrome in diazepam-dependent cats is precipitated by Ro 15-1788 and Ro 15-4513 but not by the benzodiazepine receptor antagonist ZK 93426. Neuroscience Letters. 88: 206-210. PMID 2837694 DOI: 10.1016/0304-3940(88)90127-9  0.355
1988 Corda M, Giorgi O, Longoni B, Biggio G. Decreased sensitivity to diazepam induced by chronic administration of FG 7142 Neuroscience Letters. 86: 219-224. PMID 2835714 DOI: 10.1016/0304-3940(88)90574-5  0.372
1988 Corda M, Giorgi O, Longoni B, Ongini E, Barnett A, Montaldo S, Biggio G. γ‐Aminobutyric Acid and Pentobarbital Enhance 2‐[3H]Oxoquazepam Binding to Type I Benzodiazepine Recognition Sites in Rat and Human Brain Journal of Neurochemistry. 50: 681-687. PMID 2828543 DOI: 10.1111/J.1471-4159.1988.Tb02967.X  0.404
1988 Concas A, Pepitoni S, Atsoggiu T, Toffano G, Biggio G. Aging reduces the GABA-dependent 36Cl− flux in rat brain membrane vesicles Life Sciences. 43: 1761-1771. PMID 2462147 DOI: 10.1016/0024-3205(88)90275-5  0.457
1987 Concas A, Mele S, Biggio G. Foot shock stress decreases chloride efflux from rat brain synaptoneurosomes. European Journal of Pharmacology. 135: 423-7. PMID 3582501 DOI: 10.1016/0014-2999(87)90694-7  0.401
1987 Mereu G, Corda MG, Carcangiu P, Giorgi O, Biggio G. The β-carboline ZK 93423 inhibits reticulata neurons: An effect reversed by benzodiazepine antagonists Life Sciences. 40: 1423-1430. PMID 3031400 DOI: 10.1016/0024-3205(87)90333-X  0.386
1987 Giorgi O, De Montis G, Porceddu ML, Mele S, Calderini G, Toffano G, Biggio G. Developmental and age-related changes in D1-dopamine receptors and dopamine content in the rat striatum. Brain Research. 432: 283-90. PMID 2960426 DOI: 10.1016/0165-3806(87)90053-8  0.375
1987 Porceddu ML, De Montis G, Mele S, Ongini E, Biggio G. D1 dopamine receptors in the rat retina: effect of dark adaptation and chronic blockade by SCH 23390. Brain Research. 424: 264-71. PMID 2960425 DOI: 10.1016/0006-8993(87)91470-3  0.37
1987 Porceddu ML, Giorgi O, De Montis G, Mele S, Cocco L, Ongini E, Biggio G. 6-Hydroxydopamine-induced degeneration of nigral dopamine neurons: differential effect on nigral and striatal D-1 dopamine receptors. Life Sciences. 41: 697-706. PMID 2956472 DOI: 10.1016/0024-3205(87)90449-8  0.349
1987 Giorgi O, Calderini G, Toffano G, Biggio G. D-1 dopamine receptors labelled with 3H-SCH 23390: decrease in the striatum of aged rats. Neurobiology of Aging. 8: 51-54. PMID 2951609 DOI: 10.1016/0197-4580(87)90057-1  0.406
1987 Giorgi O, Corda MG, Biggio G. The anxiolytic β-carboline ZK 93423 prevents the stress-induced increase in dopamine turnover in the prefrontal cortex European Journal of Pharmacology. 134: 327-331. PMID 2883014 DOI: 10.1016/0014-2999(87)90364-5  0.342
1987 Corda M, Giorgi O, Longoni B, Mereu G, Biggio G. Enhancement of γ-aminobutyric acid binding by the anxiolytic β-carbolines ZK 93423 and ZK 91296 Journal of Neurochemistry. 48: 1355-1358. PMID 2881979 DOI: 10.1111/J.1471-4159.1987.Tb05671.X  0.466
1987 Corda MG, Giorgi O, Mele S, Biggio G. Enhanced sensitivity to beta-carboline inverse agonists in rats chronically treated with FG 7142. Brain Research Bulletin. 19: 379-85. PMID 2824006 DOI: 10.1016/0361-9230(87)90107-9  0.405
1987 Biggio G, Concas A, Mele S, Corda MG. Changes in GABAergic transmission induced by stress, anxiogenic and anxiolytic beta-carbolines. Brain Research Bulletin. 19: 301-8. PMID 2824002 DOI: 10.1016/0361-9230(87)90098-0  0.487
1986 Porceddu ML, Giorgi O, Ongini E, Mele S, Biggio G. 3H-SCH 23390 binding sites in the rat substantia nigra: evidence for a presynaptic localization and innervation by dopamine. Life Sciences. 39: 321-8. PMID 3526066 DOI: 10.1016/0024-3205(86)90650-8  0.38
1986 Corda MG, Giorgi O, Biggio G. Behavioral and biochemical evidence for a long-lasting decrease in GABAergic function elicited by chronic administration of FG 7142 Brain Research. 384: 60-67. PMID 3024778 DOI: 10.1016/0006-8993(86)91219-9  0.493
1986 Corda MG, Biggio G. Proconflict effect of GABA receptor complex antagonists. Reversal by diazepam. Neuropharmacology. 25: 541-544. PMID 3016590 DOI: 10.1016/0028-3908(86)90181-4  0.496
1986 Corda MG, Sanna E, Concas A, Giorgi O, Ongini E, Nurchi V, Pintori T, Crisponi G, Biggio G. Enhancement of γ-aminobutyric acid binding by quazepam, a benzodiazepine derivative with preferential affinity for type I benzodiazepine receptors Journal of Neurochemistry. 47: 370-374. PMID 3016172 DOI: 10.1111/J.1471-4159.1986.Tb04511.X  0.655
1986 Corda MG, Concas A, Porceddu M, Sanna E, Biggio G. Striato-nigral denervation increases type II benzodiazepine receptors in the substantia nigra of the rat. Neuropharmacology. 25: 59-62. PMID 3005905 DOI: 10.1016/0028-3908(86)90059-6  0.505
1985 Mereu G, Collu M, Ongini E, Biggio G, Gessa GL. SCH 23390, a selective dopamine D1 antagonist, activates dopamine neurons but fails to prevent their inhibition by apomorphine. European Journal of Pharmacology. 111: 393-6. PMID 3894035 DOI: 10.1016/0014-2999(85)90649-1  0.512
1985 Corda MG, Giorgi O, Gatta F, Biggio G. Long-lasting proconflict effect induced by chronic administration of the β-carboline derivative FG 7142 Neuroscience Letters. 62: 237-240. PMID 3003625 DOI: 10.1016/0304-3940(85)90361-1  0.364
1985 Concas A, Corda MG, Biggio G. Involvement of benzodiazepine recognition sites in the foot shock-induced decrease of low affinity GABA receptors in the rat cerebral cortex Brain Research. 341: 50-56. PMID 2994815 DOI: 10.1016/0006-8993(85)91471-4  0.495
1985 Porceddu ML, Corda MG, Sanna E, Biggio G. Increase in nigral type II benzodiazepine recognition sites following striatonigral denervation. European Journal of Pharmacology. 112: 265-267. PMID 2993000 DOI: 10.1016/0014-2999(85)90507-2  0.531
1985 Corda MG, Concas A, Biggio G. Selective blockade of benzodiazepine receptors by Ro 15-1788 prevents foot shock-induced decrease of low affinity γ-aminobutyric acid receptors Neuroscience Letters. 56: 265-269. PMID 2991822 DOI: 10.1016/0304-3940(85)90253-8  0.497
1985 Concas A, Serra M, Crisponi G, Nurchi VM, Corda M, Biggio G. Changes in the characteristics of low affinity GABA binding sites elicited by Ro15-1788. Life Sciences. 36: 329-337. PMID 2981389 DOI: 10.1016/0024-3205(85)90118-3  0.44
1985 Porceddu ML, Ongini E, Biggio G. [3H]SCH 23390 binding sites increase after chronic blockade of D-1 dopamine receptors. European Journal of Pharmacology. 118: 367-370. PMID 2935413 DOI: 10.1016/0014-2999(85)90151-7  0.363
1985 Gessa GL, Porceddu ML, Collu M, Mereu G, Serra M, Ongini E, Biggio G. Sedation and sleep induced by high doses of apomorphine after blockade of D-1 receptors by SCH 23390. European Journal of Pharmacology. 109: 269-74. PMID 2859998 DOI: 10.1016/0014-2999(85)90429-7  0.521
1984 Biggio G, Concas A, Serra M, Salis M, Corda MG, Nurchi V, Crisponi C, Gessa GL. Stress and beta-carbolines decrease the density of low affinity GABA binding sites; an effect reversed by diazepam. Brain Research. 305: 13-8. PMID 6547630 DOI: 10.1016/0006-8993(84)91114-4  0.585
1984 Concas A, Serra M, Salis M, Nurchi VM, Crisponi G, Biggio G. Evidence for an involvement of gaba receptors in the mediation of the proconvulsant action of ethyl-β-carboline-3-carboxylate Neuropharmacology. 23: 323-326. PMID 6328349 DOI: 10.1016/0028-3908(84)90194-1  0.453
1983 Concas A, Salis M, Serra M, Corda MG, Biggio G. Ethyl-β-carboline-3-carboxylate decreases [3H]GABA binding in membrane preparations of rat cerebral cortex European Journal of Pharmacology. 89: 179-181. PMID 6861886 DOI: 10.1016/0014-2999(83)90627-1  0.391
1983 Concas A, Corda MG, Salis M, Mulas ML, Milia A, Corongiu FP, Biggio G. Biochemical changes in the rat cerebellar cortex elicited by chronic treatment with methyl mercury. Toxicology Letters. 18: 27-33. PMID 6312640 DOI: 10.1016/0378-4274(83)90066-8  0.397
1983 Serra M, Concas A, Salis M, Biggio G. Increase of cyclic GMP in cerebellum by methyl-6, 7-dimethoxy-4-ethyl-β-carboline-3-car☐ylate (DMCM) Brain Research. 273: 347-351. PMID 6311353 DOI: 10.1016/0006-8993(83)90860-0  0.479
1983 Concas A, Serra M, Salis M, Guarneri P, Carbini L, Padalino A, Biggio G. Effect of a vitamin A-free diet on [3H]diazepam and [3H]GABA binding in the rat retina European Journal of Pharmacology. 89: 317-319. PMID 6307714 DOI: 10.1016/0014-2999(83)90514-9  0.399
1983 Concas A, Salis M, Biggio G. Brain benzodiazepine receptors increase after chronic ethyl-β-carboline-3-carboxylate Life Sciences. 32: 1175-1182. PMID 6300577 DOI: 10.1016/0024-3205(83)90185-6  0.333
1982 Guarneri P, Corda MG, Concas A, Salis M, Calderini G, Toffano G, Biggio G. Age-related changes of benzodiazepine and GABA binding sites in the rat retina Neurobiology of Aging. 3: 227-231. PMID 6298648 DOI: 10.1016/0197-4580(82)90043-4  0.443
1981 Biggio G, Corda MG, Concas A, Demontis G, Rossetti Z, Gessa GL. Rapid changes in GABA binding induced by stress in different areas of the rat brain. Brain Research. 229: 363-9. PMID 6272938 DOI: 10.1016/0006-8993(81)91000-3  0.617
1981 Corda MG, Concas A, Rossetti Z, Guarneri P, Corongiu FP, Biggio G. Methyl mercury enhances [3H]diazepam binding in different areas of the rat brain. Brain Research. 229: 264-269. PMID 6272936 DOI: 10.1016/0006-8993(81)90769-1  0.388
1981 Biggio G, Corda MG, Concas A, Gessa GL. Denervation supersensitivity for benzodiazepine receptors in the rat substantia nigra. Brain Research. 220: 344-9. PMID 6269689 DOI: 10.1016/0006-8993(81)91223-3  0.51
1981 Biggio G, Guarneri P, Corda MG. Benzodiazepine and GABA receptors in the rat retina: effect of light and dark adaptation Brain Research. 216: 210-214. PMID 6266587 DOI: 10.1016/0006-8993(81)91291-9  0.454
1981 Guarneri P, Corda MG, Concas A, Biggio G. Kainic acid-induced lesion of rat retina: differential effect on cyclic GMP and benzodiazepine and GABA receptors Brain Research. 209: 216-220. PMID 6260302 DOI: 10.1016/0006-8993(81)91183-5  0.456
1980 Biggio G, Corda MG, Demontis G, Concas A, Gessa GL. Sudden decrease in cerebellar GABA binding induced by stress. Pharmacological Research Communications. 12: 489-93. PMID 7192408 DOI: 10.1016/S0031-6989(80)80120-2  0.61
1980 Biggio G, Casu M, Klimek V, Gessa GL. Dopamine synthesis: tolerance to haloperidol and supersensitivity to apomorphine depend on presynaptic receptors. Advances in Biochemical Psychopharmacology. 24: 17-22. PMID 6996441  0.432
1980 Casu M, Klimek V, Biggio G, Gessa GL. Tolerance to haloperidol effect on dopamine (DA) synthesis is independent from postsynaptic DA receptors. Pharmacological Research Communications. 12: 393-6. PMID 6771775 DOI: 10.1016/S0031-6989(80)80097-X  0.496
1980 Biggio G, Corda MG, De Montis G, Stefanini E, Gessa GL. Kainic acid differentiates GABA receptors from benzodiazepine receptors in the rat cerebellum. Brain Research. 193: 589-93. PMID 6248167 DOI: 10.1016/0006-8993(80)90195-X  0.615
1980 Biggio G, Corda MG, De Montis G, Gessa GL. Differential effects of kainic acid on benzodiazepine receptors, GABA receptors, and GABA-modulin in the cerebellar cortex. Advances in Biochemical Psychopharmacology. 21: 265-70. PMID 6246741  0.548
1980 Fratta W, Casu M, Balestrieri A, Loviselli A, Biggio G, Gessa GL. Failure of ketamine to interact with opiate receptors. European Journal of Pharmacology. 61: 389-91. PMID 6245894 DOI: 10.1016/0014-2999(80)90079-5  0.557
1980 Corda MG, Biggio G, Gessa GL. Brain nucleotides in naive and handling-habituated rats: differences in levels and drug-sensitivity. Brain Research. 188: 287-90. PMID 6245755 DOI: 10.1016/0006-8993(80)90579-X  0.488
1980 Biggio G, Spano P, Gessa G. Preface to the proceedings of the third Soviet-Italian Joint Meeting on Neurotransmitters and Brain Function Pharmacological Research Communications. 12: 225. DOI: 10.1016/S0031-6989(80)80005-1  0.442
1979 Biggio G, Corda MG, Lamberti C, Gessa GL. Changes in benzodiazepine receptors following GABAergic denervation of substantia nigra. European Journal of Pharmacology. 58: 215-6. PMID 499354 DOI: 10.1016/0014-2999(79)90016-5  0.573
1979 Biggio G, Corda MG, Casu M, Mulas ML, Gessa GL. GABA-receptors in the substantia nigra controlling cyclic-GMP in the cerebellar cortex. Advances in Experimental Medicine and Biology. 123: 419-27. PMID 229716  0.531
1979 Corda MG, Casu M, Biggio G. Decrease of cyclic GMP in cerebellar cortex by intrastriatal (--)-sulpiride. European Journal of Pharmacology. 55: 327-330. PMID 222600 DOI: 10.1016/0014-2999(79)90203-6  0.335
1979 Braestrup C, Nielsen M, Biggio G, Squires RF. Neuronal localisation of benzodiazepine receptors in cerebellum. Neuroscience Letters. 13: 219-224. PMID 43490 DOI: 10.1016/0304-3940(79)91497-6  0.379
1978 Spano PF, Biggio G, Casu M, Gessa GL, Bareggi SR, Govoni S, Trabucchi M. Interaction of metergoline with striatal dopamine system. Life Sciences. 23: 2383-91. PMID 745518 DOI: 10.1016/0024-3205(78)90296-5  0.488
1978 Quarantotti BP, Corda MG, Paglietti E, Biggio G, Gessa GL. Inhibition of copulatory behavior in male rats by D-Ala2-Met-enkephalinamide. Life Sciences. 23: 673-8. PMID 692287 DOI: 10.1016/0024-3205(78)90065-6  0.482
1978 Biggio G, Corda MG, Casu M, Gessa GL. Role of striatal dopamine receptors in the regulation of cerebellar cyclic GMP. Annali Dell'Istituto Superiore Di Sanitã . 14: 147-56. PMID 227304  0.438
1978 Biggio G, Corda MG, Casu M, Salis M, Gessa GL. Disappearance of cerebellar cyclic GMP induced by kainic acid. Brain Research. 154: 203-8. PMID 212160 DOI: 10.1016/0006-8993(78)91073-9  0.45
1978 Biggio G, Corda MG, Casu M, Gessa GL. Kainic acid-induced lesion of dopaminergic target cells in the striatum: consequences on the dynamics of cerebellar cGMP. Naunyn-Schmiedeberg's Archives of Pharmacology. 304: 5-7. PMID 211448 DOI: 10.1007/Bf00501370  0.497
1978 Biggio G, Corda MG, Casu M, Gessa GL. Decrease of cyclic GMP in cerebellum by intrastriatal D-Ala2-met-enkephalinamide. Life Sciences. 23: 335-9. PMID 211360 DOI: 10.1016/0024-3205(78)90017-6  0.551
1978 Biggio G, Corda MG, Casu M, Gessa GL. Striato-cerebellar pathway controlling cyclic GMP content in the cerebellum: role of dopamine, GABA and enkephalins. Advances in Biochemical Psychopharmacology. 18: 227-44. PMID 206110  0.466
1978 Biggio G, Casu M, Corda MG, Di Bello C, Gessa GL. Stimulation of dopamine synthesis in caudate nucleus by intrastriatal enkephalins and antagonism by naloxone. Science (New York, N.Y.). 200: 552-4. PMID 205949 DOI: 10.1126/Science.205949  0.509
1978 Biggio G, Corda MG, Casu M, Gessa GL. Effect of chronic treatment with neuroleptics on the content of 3',5'-cyclic guanosine monophosphate in cerebellar cortex of rats. Life Sciences. 23: 649-52. PMID 29201 DOI: 10.1016/0024-3205(78)90048-6  0.532
1977 Biggio G, Casu M, Corda MG, Vernaleone F, Gessa GL. Effect of muscimol, a GABA-mimetic agent, on dopamine metabolism in the mouse brain. Life Sciences. 21: 525-31. PMID 904431 DOI: 10.1016/0024-3205(77)90092-3  0.521
1977 Biggio G, Piccardi MP, Porceddu ML, Gessa GL. Changes in gastro-intestinal serotonin content associated with fasting and satiation. Experientia. 33: 745-6. PMID 891734 DOI: 10.1007/Bf01944166  0.441
1977 Fratta W, Biggio G, Gessa GL. Homosexual mounting behavior induced in male rats and rabbits by a tryptophan-free diet. Life Sciences. 21: 379-83. PMID 302380 DOI: 10.1016/0024-3205(77)90518-5  0.487
1977 Biggio G, Costa E, Guidotti A. Regulation of 3', 5'-cyclic guanosine monophosphate content in deep cerebellar nuclei. Neuroscience. 2: 49-52. PMID 199855 DOI: 10.1016/0306-4522(77)90067-7  0.56
1977 Biggio G, Brodie BB, Costa E, Guidotti A. Mechanisms by which diazepam, muscimol, and other drugs change the content of cGMP in cerebellar cortex. Proceedings of the National Academy of Sciences of the United States of America. 74: 3592-6. PMID 198792 DOI: 10.1073/Pnas.74.8.3592  0.5
1977 Biggio G, Guidotti A, Costa E. On the mechanism of the decrease in cerebellar cyclic GMP content elicited by opiate receptor agonists. Naunyn-Schmiedeberg's Archives of Pharmacology. 296: 117-21. PMID 189228  0.507
1977 Biggio G, Costa E, Guidotti A. Pharmacologically induced changes in the 3':5'-cyclic guanosine monophosphate content of rat cerebellar cortex: difference between apomorphine, haloperidol and harmaline. The Journal of Pharmacology and Experimental Therapeutics. 200: 207-15. PMID 13199  0.303
1976 Biggio G, Porceddu ML, Gessa GL. Decrease of homovanillic, dihydroxyphenylacetic acid and cyclic-adenosine-3',5'-monophosphate content in the rat caudate nucleus induced by the acute administration of an aminoacid mixture lacking tyrosine and phenylalanine. Journal of Neurochemistry. 26: 1253-5. PMID 180254 DOI: 10.1111/j.1471-4159.1976.tb07014.x  0.449
1975 Guidotti A, Biggio G, Costa E. 3-Acetylpyridine: a tool to inhibit the tremor and the increase of cGMP content in cerebellar cortex elicited by harmaline. Brain Research. 96: 201-5. PMID 169960  0.434
1974 Biggio G, Fadda F, Fanni P, Tagliamonte A, Gessa GL. Rapid depletion of serum tryptophan, brain tryptophan, serotonin and 5-hydroxyindoleacetic acid by a tryptophan-free diet. Life Sciences. 14: 1321-9. PMID 4823644 DOI: 10.1016/0024-3205(74)90440-8  0.463
1974 Tagliamonte A, Gessa R, Biggio G, Vargiu L, Gessa GL. Daily changes of free serum tryptophan in humans. Life Sciences. 14: 349-54. PMID 4813595 DOI: 10.1016/0024-3205(74)90065-4  0.468
1974 Gessa GL, Biggio G, Vargiu L, Napoleone F, Tagliamonte A. Norepinephrine and dopamine concentrations in the cerebral cortex of man, monkeys and other mammals. Experientia. 30: 1295-6. PMID 4435171 DOI: 10.1007/Bf01945194  0.417
1974 Gessa GL, Biggio G, Fadda F, Corsini GU, Tagliamonte A. Effect of the oral administration of tryptophan-free amino acid mixtures on serum tryptophan, brain tryptophan and serotonin metabolism. Journal of Neurochemistry. 22: 869-70. PMID 4407107 DOI: 10.1111/J.1471-4159.1974.Tb04308.X  0.463
1974 Gessa GL, Vargiu L, Biggio G, Tagliamonte A. Effect of methadone on brain dopamine metabolism Biochemical Pharmacology. 23: 841-844. DOI: 10.1016/0006-2952(74)90144-0  0.335
1973 Tagliamonte A, Biggio G, Vargiu L, Gessa GL. Increase of brain tryptophan and stimulation of serotonin synthesis by salicylate. Journal of Neurochemistry. 20: 909-12. PMID 4703803 DOI: 10.1111/J.1471-4159.1973.Tb00054.X  0.46
1973 Tagliamonte A, Biggio G, Vargiu L, Gessa GL. Free tryptophan in serum controls brain tryptophan level and serotonin synthesis. Life Sciences. Pt. 2: Biochemistry, General and Molecular Biology. 12: 277-87. PMID 4701854 DOI: 10.1016/0024-3205(73)90361-5  0.481
Show low-probability matches.