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Lucas Brunsveld - Publications

Affiliations: 
2008- Biomedical Engineering Eindhoven University of Technology, Eindhoven, Noord-Brabant, Netherlands 
Area:
Chemical Biology
Website:
https://www.tue.nl/en/research/researchers/luc-brunsveld
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Maurya GP, Verma D, Sinha A, Brunsveld L, Haridas V. Hydrophobicity Directed Chiral Self-Assembly and Aggregation-Induced Emission: Diacetylene-Cored Pseudopeptide Chiral Dopants. Angewandte Chemie (International Ed. in English). e202209806. PMID 36006397 DOI: 10.1002/anie.202209806  0.547
2020 Wolter M, de Vink P, Neves JF, Srdanovic S, Higuchi Y, Kato N, Wilson AJ, Landrieu I, Brunsveld L, Ottmann C. Selectivity via Cooperativity: Preferential Stabilization of the p65/14-3-3 interaction with Semi-Synthetic Natural Products. Journal of the American Chemical Society. PMID 32501683 DOI: 10.1021/Jacs.0C02151  0.42
2017 Stevers LM, Sijbesma E, Botta M, MacKintosh C, Obsil T, Landrieu I, Cau Y, Wilson AJ, Karawajczyk A, Eickhoff J, Davis J, Hann MM, O'Mahony G, Doveston RG, Brunsveld L, et al. Modulators of 14-3-3 Protein-Protein Interactions. Journal of Medicinal Chemistry. PMID 28968506 DOI: 10.1021/Acs.Jmedchem.7B00574  0.441
2012 Görmer K, Bürger M, Kruijtzer JA, Vetter I, Vartak N, Brunsveld L, Bastiaens PI, Liskamp RM, Triola G, Waldmann H. Chemical-biological exploration of the limits of the Ras de- and repalmitoylating machinery. Chembiochem : a European Journal of Chemical Biology. 13: 1017-23. PMID 22488913 DOI: 10.1002/Cbic.201200078  0.559
2011 Möcklinghoff S, van Otterlo WA, Rose R, Fuchs S, Zimmermann TJ, Dominguez Seoane M, Waldmann H, Ottmann C, Brunsveld L. Design and evaluation of fragment-like estrogen receptor tetrahydroisoquinoline ligands from a scaffold-detection approach. Journal of Medicinal Chemistry. 54: 2005-11. PMID 21381753 DOI: 10.1021/Jm1011116  0.496
2010 Chen YX, Koch S, Uhlenbrock K, Weise K, Das D, Gremer L, Brunsveld L, Wittinghofer A, Winter R, Triola G, Waldmann H. Synthesis of the Rheb and K-Ras4B GTPases. Angewandte Chemie (International Ed. in English). 49: 6090-5. PMID 20652921 DOI: 10.1002/Anie.201001884  0.531
2010 Triola G, Gerauer M, Görmer K, Brunsveld L, Waldmann H. Solid-phase synthesis of lipidated Ras peptides employing the Ellman sulfonamide linker. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 9585-91. PMID 20648498 DOI: 10.1002/Chem.201001642  0.563
2010 Dekker FJ, Rocks O, Vartak N, Menninger S, Hedberg C, Balamurugan R, Wetzel S, Renner S, Gerauer M, Schölermann B, Rusch M, Kramer JW, Rauh D, Coates GW, Brunsveld L, et al. Small-molecule inhibition of APT1 affects Ras localization and signaling. Nature Chemical Biology. 6: 449-56. PMID 20418879 DOI: 10.1038/Nchembio.362  0.692
2010 Rocks O, Gerauer M, Vartak N, Koch S, Huang ZP, Pechlivanis M, Kuhlmann J, Brunsveld L, Chandra A, Ellinger B, Waldmann H, Bastiaens PI. The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins. Cell. 141: 458-71. PMID 20416930 DOI: 10.1016/J.Cell.2010.04.007  0.559
2009 Renner S, Van Otterlo WAL, Dominguez Seoane M, Möcklinghoff S, Hofmann B, Wetzel S, Schuffenhauer A, Ertl P, Oprea TI, Steinhilber D, Brunsveld L, Rauh D, Waldmann H. Bioactivity-guided mapping and navigation of chemical space Nature Chemical Biology. 5: 585-592. PMID 19561619 DOI: 10.1038/Nchembio.188  0.509
2009 Weise K, Triola G, Brunsveld L, Waldmann H, Winter R. Influence of the lipidation motif on the partitioning and association of N-Ras in model membrane subdomains. Journal of the American Chemical Society. 131: 1557-64. PMID 19133719 DOI: 10.1016/J.Bpj.2008.12.3224  0.574
2009 Alexander M, Gerauer M, Pechlivanis M, Popkirova B, Dvorsky R, Brunsveld L, Waldmann H, Kuhlmann J. Mapping the isoprenoid binding pocket of PDEdelta by a semisynthetic, photoactivatable N-Ras lipoprotein. Chembiochem : a European Journal of Chemical Biology. 10: 98-108. PMID 18846587 DOI: 10.1002/Cbic.200800275  0.578
2009 Brunsveld L, Waldmann H, Huster D. Membrane binding of lipidated Ras peptides and proteins - The structural point of view Biochimica Et Biophysica Acta - Biomembranes. 1788: 273-288. PMID 18771652 DOI: 10.1016/J.Bbamem.2008.08.006  0.594
2008 Guo Z, Wu YW, Das D, Delon C, Cramer J, Yu S, Thuns S, Lupilova N, Waldmann H, Brunsveld L, Goody RS, Alexandrov K, Blankenfeldt W. Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. The Embo Journal. 27: 2444-56. PMID 18756270 DOI: 10.1038/Emboj.2008.164  0.591
2008 Triola G, Brunsveld L, Waldmann H. Racemization-free synthesis of S-alkylated cysteines via thiol-ene reaction Journal of Organic Chemistry. 73: 3646-3649. PMID 18376863 DOI: 10.1021/Jo800198S  0.509
2006 Brunsveld L, Kuhlmann J, Alexandrov K, Wittinghofer A, Goody RS, Waldmann H. Lipidated ras and rab peptides and proteins--synthesis, structure, and function. Angewandte Chemie (International Ed. in English). 45: 6622-46. PMID 17031879 DOI: 10.1002/Anie.200600855  0.592
2006 Brunsveld L, Kuhlmann J, Waldmann H. Synthesis of palmitoylated Ras-peptides and -proteins. Methods (San Diego, Calif.). 40: 151-65. PMID 17012027 DOI: 10.1016/J.Ymeth.2006.04.014  0.58
2006 Gelb MH, Brunsveld L, Hrycyna CA, Michaelis S, Tamanoi F, Van Voorhis WC, Waldmann H. Therapeutic intervention based on protein prenylation and associated modifications. Nature Chemical Biology. 2: 518-28. PMID 16983387 DOI: 10.1038/Nchembio818  0.568
2006 Goody RS, Durek T, Waldmann H, Brunsveld L, Alexandrov K. Application of protein semisynthesis for the construction of functionalized posttranslationally modified rab GTPases. Methods in Enzymology. 403: 29-42. PMID 16473575 DOI: 10.1016/S0076-6879(05)03004-1  0.599
2006 Pylypenko O, Rak A, Durek T, Kushnir S, Dursina BE, Thomae NH, Constantinescu AT, Brunsveld L, Watzke A, Waldmann H, Goody RS, Alexandrov K. Structure of doubly prenylated Ypt1:GDI complex and the mechanism of GDI-mediated Rab recycling. The Embo Journal. 25: 13-23. PMID 16395334 DOI: 10.1038/Sj.Emboj.7600921  0.578
2006 Brunsveld L, Watzke A, Durek T, Alexandrov K, Goody RS, Waldmann H. Synthesis of functionalized rab GTPases by a combination of solution- or solid-phase lipopeptide synthesis with expressed protein ligation. Chemistry (Weinheim An Der Bergstrasse, Germany). 11: 2756-72. PMID 15729676 DOI: 10.1002/Chem.200401041  0.601
2005 Watzke A, Brunsveld L, Durek T, Alexandrov K, Rak A, Goody RS, Waldmann H. Chemical biology of protein lipidation: semi-synthesis and structure elucidation of prenylated RabGTPases. Organic & Biomolecular Chemistry. 3: 1157-64. PMID 15785799 DOI: 10.1039/B417573E  0.615
2003 Rak A, Pylypenko O, Durek T, Watzke A, Kushnir S, Brunsveld L, Waldmann H, Goody RS, Alexandrov K. Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase. Science (New York, N.Y.). 302: 646-50. PMID 14576435 DOI: 10.1126/Science.1087761  0.575
2002 Brunsveld L, Vekemans JA, Hirschberg JH, Sijbesma RP, Meijer EW. Hierarchical formation of helical supramolecular polymers via stacking of hydrogen-bonded pairs in water. Proceedings of the National Academy of Sciences of the United States of America. 99: 4977-82. PMID 11929978 DOI: 10.1073/Pnas.072659099  0.48
2001 Brunsveld L, Folmer BJ, Meijer EW, Sijbesma RP. Supramolecular polymers. Chemical Reviews. 101: 4071-98. PMID 11740927 DOI: 10.1021/cr990125q  0.22
2001 Prince RB, Moore JS, Brunsveld L, Meijer EW. Cooperativity in the folding of helical m-phenylene ethynylene oligomers based upon the 'sergeants-and-soldiers' principle. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 4150-4. PMID 11686593 DOI: 10.1002/1521-3765(20011001)7:19<4150::Aid-Chem4150>3.0.Co;2-F  0.737
2001 Brunsveld L, Meijer EW, Prince RB, Moore JS. Self-assembly of folded m-phenylene ethynylene oligomers into helical columns. Journal of the American Chemical Society. 123: 7978-84. PMID 11506553 DOI: 10.1021/Ja010751G  0.737
2000 Hirschberg JH, Brunsveld L, Ramzi A, Vekemans JA, Sijbesma RP, Meijer EW. Helical self-assembled polymers from cooperative stacking of hydrogen-bonded pairs. Nature. 407: 167-70. PMID 11001050 DOI: 10.1038/35025027  0.522
2000 Brunsveld L, Prince RB, Meijer EW, Moore JS. Conformational ordering of apolar, chiral m-phenylene ethynylene oligomers Organic Letters. 2: 1525-8. PMID 10841470 DOI: 10.1021/Ol0056877  0.732
2000 Prince RB, Brunsveld L, Meijer EW, Moore JS. Twist Sense Bias Induced by Chiral Side Chains in Helically Folded Oligomers. Angewandte Chemie (International Ed. in English). 39: 228-230. PMID 10649384 DOI: 10.1002/(Sici)1521-3773(20000103)39:1<228::Aid-Anie228>3.0.Co;2-B  0.731
1997 Sijbesma RP, Beijer FH, Brunsveld L, Folmer BJ, Hirschberg JH, Lange RF, Lowe JK, Meijer EW. Reversible polymers formed from self-complementary monomers using quadruple hydrogen bonding. Science (New York, N.Y.). 278: 1601-4. PMID 9374454 DOI: 10.1126/Science.278.5343.1601  0.447
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