Ulrich Dirnagl - Publications

Affiliations: 
Experimental Neurology Charité - Universitätsmedizin Berlin, Germany 

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Year Citation  Score
2018 Khalil AA, Mueller S, Foddis M, Mosch L, Lips J, Przesdzing I, Temme S, Flögel U, Dirnagl U, Boehm-Sturm P. Longitudinal 19F magnetic resonance imaging of brain oxygenation in a mouse model of vascular cognitive impairment using a cryogenic radiofrequency coil. Magma (New York, N.Y.). PMID 30421249 DOI: 10.1007/s10334-018-0712-x  0.32
2018 Crespo-Garcia S, Reichhart N, Skosyrski S, Foddis M, Wu J, Figura A, Herrspiegel C, Füchtemeier M, Sassi C, Dirnagl U, Joussen AM, Strauss O. Correction: Individual and temporal variability of the retina after chronic bilateral common carotid artery occlusion (BCCAO). Plos One. 13: e0196538. PMID 29684064 DOI: 10.1371/journal.pone.0196538  0.32
2018 Crespo-Garcia S, Reichhart N, Skosyrski S, Foddis M, Wu J, Figura A, Herrspiegel C, Füchtemeier M, Sassi C, Dirnagl U, Joussen AM, Strauss O. Individual and temporal variability of the retina after chronic bilateral common carotid artery occlusion (BCCAO). Plos One. 13: e0193961. PMID 29547662 DOI: 10.1371/journal.pone.0193961  0.32
2017 Koch S, Mueller S, Foddis M, Bienert T, von Elverfeldt D, Knab F, Farr TD, Bernard R, Dopatka M, Rex A, Dirnagl U, Harms C, Boehm-Sturm P. Atlas registration for edema-corrected MRI lesion volume in mouse stroke models. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17726635. PMID 28829217 DOI: 10.1177/0271678X17726635  0.32
2017 Dam K, Füchtemeier M, Farr TD, Boehm-Sturm P, Foddis M, Dirnagl U, Malysheva O, Caudill MA, Jadavji NM. Increased homocysteine levels impair reference memory and reduce cortical levels of acetylcholine in a mouse model of vascular cognitive impairment. Behavioural Brain Research. 321: 201-208. PMID 28087280 DOI: 10.1016/j.bbr.2016.12.041  0.32
2017 Boehm-Sturm P, Füchtemeier M, Foddis M, Mueller S, Trueman RC, Zille M, Rinnenthal JL, Kypraios T, Shaw L, Dirnagl U, Farr TD. Neuroimaging Biomarkers Predict Brain Structural Connectivity Change in a Mouse Model of Vascular Cognitive Impairment. Stroke. PMID 28070001 DOI: 10.1161/STROKEAHA.116.014394  0.32
2016 Laginha I, Kopp MA, Druschel C, Schaser KD, Brommer B, Hellmann RC, Watzlawick R, Ossami-Saidi RR, Prüss H, Failli V, Meisel C, Liebscher T, Prilipp E, Niedeggen A, Ekkernkamp A, ... ... Dirnagl U, et al. Natural Killer (NK) Cell Functionality after human Spinal Cord Injury (SCI): protocol of a prospective, longitudinal study. Bmc Neurology. 16: 170. PMID 27618987 DOI: 10.1186/s12883-016-0681-5  0.32
2016 Donath S, An J, Lee SL, Gertz K, Datwyler AL, Harms U, Müller S, Farr TD, Füchtemeier M, Lättig-Tünnemann G, Lips J, Foddis M, Mosch L, Bernard R, Grittner U, ... ... Dirnagl U, et al. Interaction of ARC and Daxx: A Novel Endogenous Target to Preserve Motor Function and Cell Loss after Focal Brain Ischemia in Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8132-48. PMID 27488634 DOI: 10.1523/JNEUROSCI.4428-15.2016  0.32
2016 Kopp MA, Liebscher T, Watzlawick R, Martus P, Laufer S, Blex C, Schindler R, Jungehulsing GJ, Knüppel S, Kreutzträger M, Ekkernkamp A, Dirnagl U, Strittmatter SM, Niedeggen A, Schwab JM. SCISSOR-Spinal Cord Injury Study on Small molecule-derived Rho inhibition: a clinical study protocol. Bmj Open. 6: e010651. PMID 27466236 DOI: 10.1136/bmjopen-2015-010651  0.32
2016 Watzlawick R, Rind J, Sena ES, Brommer B, Zhang T, Kopp MA, Dirnagl U, Macleod MR, Howells DW, Schwab JM. Olfactory Ensheathing Cell Transplantation in Experimental Spinal Cord Injury: Effect size and Reporting Bias of 62 Experimental Treatments: A Systematic Review and Meta-Analysis. Plos Biology. 14: e1002468. PMID 27244556 DOI: 10.1371/journal.pbio.1002468  0.32
2016 Winek K, Engel O, Koduah P, Heimesaat MM, Fischer A, Bereswill S, Dames C, Kershaw O, Gruber AD, Curato C, Oyama N, Meisel C, Meisel A, Dirnagl U. Depletion of Cultivatable Gut Microbiota by Broad-Spectrum Antibiotic Pretreatment Worsens Outcome After Murine Stroke. Stroke; a Journal of Cerebral Circulation. PMID 27056982 DOI: 10.1161/STROKEAHA.115.011800  0.32
2016 Neeb L, Hellen P, Hoffmann J, Dirnagl U, Reuter U. Methylprednisolone blocks interleukin 1 beta induced calcitonin gene related peptide release in trigeminal ganglia cells. The Journal of Headache and Pain. 17: 19. PMID 26931452 DOI: 10.1186/s10194-016-0609-x  0.32
2016 Scherbakov N, Ebner N, Sandek A, Meisel A, Haeusler KG, von Haehling S, Anker SD, Dirnagl U, Joebges M, Doehner W. Influence of essential amino acids on muscle mass and muscle strength in patients with cerebral stroke during early rehabilitation: protocol and rationale of a randomized clinical trial (AMINO-Stroke Study). Bmc Neurology. 16: 10. PMID 26793971 DOI: 10.1186/s12883-016-0531-5  0.32
2015 Engel O, Akyüz L, da Costa Goncalves AC, Winek K, Dames C, Thielke M, Herold S, Böttcher C, Priller J, Volk HD, Dirnagl U, Meisel C, Meisel A. Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke. Stroke; a Journal of Cerebral Circulation. 46: 3232-40. PMID 26451017 DOI: 10.1161/STROKEAHA.115.008989  0.32
2015 Leithner C, Füchtemeier M, Jorks D, Mueller S, Dirnagl U, Royl G. Infarct Volume Prediction by Early Magnetic Resonance Imaging in a Murine Stroke Model Depends on Ischemia Duration and Time of Imaging. Stroke; a Journal of Cerebral Circulation. PMID 26451016 DOI: 10.1161/STROKEAHA.114.007832  0.32
2015 Begley CG, Buchan AM, Dirnagl U. Robust research: Institutions must do their part for reproducibility. Nature. 525: 25-7. PMID 26333454 DOI: 10.1038/525025a  0.32
2015 Römer C, Engel O, Winek K, Hochmeister S, Zhang T, Royl G, Klehmet J, Dirnagl U, Meisel C, Meisel A. Blocking stroke-induced immunodeficiency increases CNS antigen-specific autoreactivity but does not worsen functional outcome after experimental stroke. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 7777-94. PMID 25995466 DOI: 10.1523/JNEUROSCI.1532-14.2015  0.32
2015 Østergaard L, Dreier JP, Hadjikhani N, Jespersen SN, Dirnagl U, Dalkara T. Neurovascular coupling during cortical spreading depolarization and -depression. Stroke; a Journal of Cerebral Circulation. 46: 1392-401. PMID 25882051 DOI: 10.1161/STROKEAHA.114.008077  0.32
2015 Hoffmann CJ, Harms U, Rex A, Szulzewsky F, Wolf SA, Grittner U, Lättig-Tünnemann G, Sendtner M, Kettenmann H, Dirnagl U, Endres M, Harms C. Vascular signal transducer and activator of transcription-3 promotes angiogenesis and neuroplasticity long-term after stroke. Circulation. 131: 1772-82. PMID 25794850 DOI: 10.1161/CIRCULATIONAHA.114.013003  0.32
2015 Jadavji NM, Farr TD, Lips J, Khalil AA, Boehm-Sturm P, Foddis M, Harms C, Füchtemeier M, Dirnagl U. Elevated levels of plasma homocysteine, deficiencies in dietary folic acid and uracil-DNA glycosylase impair learning in a mouse model of vascular cognitive impairment. Behavioural Brain Research. 283: 215-26. PMID 25655513 DOI: 10.1016/j.bbr.2015.01.040  0.32
2015 Füchtemeier M, Brinckmann MP, Foddis M, Kunz A, Po C, Curato C, Dirnagl U, Farr TD. Vascular change and opposing effects of the angiotensin type 2 receptor in a mouse model of vascular cognitive impairment. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 476-84. PMID 25492118 DOI: 10.1038/jcbfm.2014.221  0.32
2015 Llovera G, Hofmann K, Roth S, Salas-Pérdomo A, Ferrer-Ferrer M, Perego C, Zanier ER, Mamrak U, Rex A, Party H, Agin V, Fauchon C, Orset C, Haelewyn B, De Simoni MG, ... Dirnagl U, et al. Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia Science Translational Medicine. 7. DOI: 10.1126/scitranslmed.aaa9853  0.32
2015 Lauritzen M, Dirnagl U. The Journal of Cerebral Blood Flow and Metabolism clinical, inaugural issue Journal of Cerebral Blood Flow and Metabolism. DOI: 10.1038/jcbfm.2015.187  0.32
2015 Jadavji NM, Wieske F, Dirnagl U, Winter C. Methylenetetrahydrofolate reductase deficiency alters levels of glutamate and γ-aminobutyric acid in brain tissue Molecular Genetics and Metabolism Reports. 3: 1-4. DOI: 10.1016/j.ymgmr.2015.02.001  0.32
2014 Duda GN, Grainger DW, Frisk ML, Bruckner-Tuderman L, Carr A, Dirnagl U, Einhäupl KM, Gottschalk S, Gruskin E, Huber C, June CH, Mooney DJ, Rietschel ET, Schütte G, Seeger W, et al. Changing the mindset in life sciences toward translation: a consensus. Science Translational Medicine. 6: 264cm12. PMID 25429054 DOI: 10.1126/scitranslmed.aaa0599  0.32
2014 Springer J, Schust S, Peske K, Tschirner A, Rex A, Engel O, Scherbakov N, Meisel A, von Haehling S, Boschmann M, Anker SD, Dirnagl U, Doehner W. Catabolic signaling and muscle wasting after acute ischemic stroke in mice: indication for a stroke-specific sarcopenia. Stroke; a Journal of Cerebral Circulation. 45: 3675-83. PMID 25352483 DOI: 10.1161/STROKEAHA.114.006258  0.32
2014 Dirnagl U. Modeling immunity and inflammation in stroke: can mice be trusted? Stroke; a Journal of Cerebral Circulation. 45: e177-8. PMID 25061077 DOI: 10.1161/STROKEAHA.114.005640  0.32
2014 Zille M, Harhausen D, De Saint-Hubert M, Michel R, Reutelingsperger CP, Dirnagl U, Wunder A. A dual-labeled Annexin A5 is not suited for SPECT imaging of brain cell death in experimental murine stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34. PMID 24984896 DOI: 10.1038/jcbfm.2014.115  0.32
2014 Kimmelman J, Mogil JS, Dirnagl U. Distinguishing between exploratory and confirmatory preclinical research will improve translation. Plos Biology. 12: e1001863. PMID 24844265 DOI: 10.1371/journal.pbio.1001863  0.32
2014 Yildirim F, Ji S, Kronenberg G, Barco A, Olivares R, Benito E, Dirnagl U, Gertz K, Endres M, Harms C, Meisel A. Histone acetylation and CREB binding protein are required for neuronal resistance against ischemic injury. Plos One. 9: e95465. PMID 24748101 DOI: 10.1371/journal.pone.0095465  0.32
2014 Schäbitz WR, Dirnagl U. Are we ready to translate T-cell transmigration in stroke? Stroke; a Journal of Cerebral Circulation. 45: 1610-1. PMID 24743434 DOI: 10.1161/STROKEAHA.114.005294  0.32
2014 Dirnagl U, Endres M. Found in translation: preclinical stroke research predicts human pathophysiology, clinical phenotypes, and therapeutic outcomes. Stroke; a Journal of Cerebral Circulation. 45: 1510-8. PMID 24652307 DOI: 10.1161/STROKEAHA.113.004075  0.32
2014 Macleod MR, Michie S, Roberts I, Dirnagl U, Chalmers I, Ioannidis JP, Al-Shahi Salman R, Chan AW, Glasziou P. Biomedical research: increasing value, reducing waste. Lancet. 383: 101-4. PMID 24411643 DOI: 10.1016/S0140-6736(13)62329-6  0.32
2014 Watzlawick R, Sena ES, Dirnagl U, Brommer B, Kopp MA, Macleod MR, Howells DW, Schwab JM. Effect and reporting bias of RhoA/ROCK-blockade intervention on locomotor recovery after spinal cord injury: a systematic review and meta-analysis. Jama Neurology. 71: 91-9. PMID 24297045 DOI: 10.1001/jamaneurol.2013.4684  0.32
2014 Stöber F, Baldauf K, Ziabreva I, Harhausen D, Zille M, Neubert J, Reymann KG, Scheich H, Dirnagl U, Schröder UH, Wunder A, Goldschmidt J. Single-cell resolution mapping of neuronal damage in acute focal cerebral ischemia using thallium autometallography. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 144-52. PMID 24129748 DOI: 10.1038/jcbfm.2013.177  0.32
2013 Scherbakov N, von Haehling S, Anker SD, Dirnagl U, Doehner W. Stroke induced Sarcopenia: muscle wasting and disability after stroke. International Journal of Cardiology. 170: 89-94. PMID 24231058 DOI: 10.1016/j.ijcard.2013.10.031  0.32
2013 Kopp MA, Druschel C, Meisel C, Liebscher T, Prilipp E, Watzlawick R, Cinelli P, Niedeggen A, Schaser KD, Wanner GA, Curt A, Lindemann G, Nugaeva N, Fehlings MG, Vajkoczy P, ... ... Dirnagl U, et al. The SCIentinel study--prospective multicenter study to define the spinal cord injury-induced immune depression syndrome (SCI-IDS)--study protocol and interim feasibility data. Bmc Neurology. 13: 168. PMID 24206943 DOI: 10.1186/1471-2377-13-168  0.32
2013 Baron JC, Macrae IM, Adams HP, Dirnagl U. ESC-BRAIN: experimental and clinical stroke research--do they connect?. Meeting report of the ESC-BRAIN joint symposium held in London and Shanghai in May 2013. Cerebrovascular Diseases (Basel, Switzerland). 36: 306-21. PMID 24192895 DOI: 10.1159/000355027  0.32
2013 Harhausen D, Sudmann V, Khojasteh U, Müller J, Zille M, Graham K, Thiele A, Dyrks T, Dirnagl U, Wunder A. Specific imaging of inflammation with the 18 kDa translocator protein ligand DPA-714 in animal models of epilepsy and stroke. Plos One. 8: e69529. PMID 23936336 DOI: 10.1371/journal.pone.0069529  0.32
2013 Iadecola C, Dirnagl U. The microcircualtion--fantastic voyage: introduction. Stroke; a Journal of Cerebral Circulation. 44: S83. PMID 23709740 DOI: 10.1161/STROKEAHA.112.680215  0.32
2013 Dirnagl U, Hakim A, Macleod M, Fisher M, Howells D, Alan SM, Steinberg G, Planas A, Boltze J, Savitz S, Iadecola C, Meairs S. A concerted appeal for international cooperation in preclinical stroke research. Stroke; a Journal of Cerebral Circulation. 44: 1754-60. PMID 23598526 DOI: 10.1161/STROKEAHA.113.000734  0.32
2013 Knops M, Werner CG, Scherbakov N, Fiebach J, Dreier JP, Meisel A, Heuschmann PU, Jungehülsing GJ, von Haehling S, Dirnagl U, Anker SD, Doehner W. Investigation of changes in body composition, metabolic profile and skeletal muscle functional capacity in ischemic stroke patients: the rationale and design of the Body Size in Stroke Study (BoSSS). Journal of Cachexia, Sarcopenia and Muscle. 4: 199-207. PMID 23483531 DOI: 10.1007/s13539-013-0103-0  0.32
2013 Harms C, Datwyler AL, Wiekhorst F, Trahms L, Lindquist R, Schellenberger E, Mueller S, Schütz G, Roohi F, Ide A, Füchtemeier M, Gertz K, Kronenberg G, Harms U, Endres M, ... Dirnagl U, et al. Certain types of iron oxide nanoparticles are not suited to passively target inflammatory cells that infiltrate the brain in response to stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: e1-9. PMID 23443176 DOI: 10.1038/jcbfm.2013.22  0.32
2013 Hetze S, Engel O, Römer C, Mueller S, Dirnagl U, Meisel C, Meisel A. Superiority of preventive antibiotic treatment compared with standard treatment of poststroke pneumonia in experimental stroke: a bed to bench approach. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 846-54. PMID 23361393 DOI: 10.1038/jcbfm.2013.6  0.32
2013 Mergenthaler P, Muselmann C, Sünwoldt J, Isaev NK, Wieloch T, Dirnagl U, Meisel A, Ruscher K. A functional role of the cyclin-dependent kinase inhibitor 1 (p21(WAF1/CIP1)) for neuronal preconditioning. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 351-5. PMID 23299246 DOI: 10.1038/jcbfm.2012.213  0.32
2013 Dreier JP, Victorov IV, Petzold GC, Major S, Windmüller O, Fernández-Klett F, Kandasamy M, Dirnagl U, Priller J. Electrochemical failure of the brain cortex is more deleterious when it is accompanied by low perfusion. Stroke; a Journal of Cerebral Circulation. 44: 490-6. PMID 23287786 DOI: 10.1161/STROKEAHA.112.660589  0.32
2013 Enzmann G, Mysiorek C, Gorina R, Cheng YJ, Ghavampour S, Hannocks MJ, Prinz V, Dirnagl U, Endres M, Prinz M, Beschorner R, Harter PN, Mittelbronn M, Engelhardt B, Sorokin L. The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury. Acta Neuropathologica. 125: 395-412. PMID 23269317 DOI: 10.1007/s00401-012-1076-3  0.32
2013 Capela JP, da Costa Araújo S, Costa VM, Ruscher K, Fernandes E, Bastos Mde L, Dirnagl U, Meisel A, Carvalho F. The neurotoxicity of hallucinogenic amphetamines in primary cultures of hippocampal neurons. Neurotoxicology. 34: 254-63. PMID 22983118 DOI: 10.1016/j.neuro.2012.09.005  0.32
2013 Dirnagl U, Priller J. Focal Cerebral Ischemia: The Multifaceted Role of Glial Cells Neuroglia. DOI: 10.1093/acprof:oso/9780195152227.003.0041  0.32
2013 Mergenthaler P, Dirnagl U, Kunz A. Ischemic stroke: Basic pathophysiology and clinical implication Neuroscience in the 21st Century: From Basic to Clinical. 2543-2563. DOI: 10.1007/978-1-4614-1997-6_97  0.32
2012 Failli V, Kopp MA, Gericke C, Martus P, Klingbeil S, Brommer B, Laginha I, Chen Y, DeVivo MJ, Dirnagl U, Schwab JM. Functional neurological recovery after spinal cord injury is impaired in patients with infections. Brain : a Journal of Neurology. 135: 3238-50. PMID 23100450 DOI: 10.1093/brain/aws267  0.32
2012 Dirnagl U. Pathobiology of injury after stroke: the neurovascular unit and beyond. Annals of the New York Academy of Sciences. 1268: 21-5. PMID 22994217 DOI: 10.1111/j.1749-6632.2012.06691.x  0.32
2012 Apostolova I, Wunder A, Dirnagl U, Michel R, Stemmer N, Lukas M, Derlin T, Gregor-Mamoudou B, Goldschmidt J, Brenner W, Buchert R. Brain perfusion SPECT in the mouse: normal pattern according to gender and age. Neuroimage. 63: 1807-17. PMID 22971548 DOI: 10.1016/j.neuroimage.2012.08.038  0.32
2012 Hoffmann J, Wecker S, Neeb L, Dirnagl U, Reuter U. Primary trigeminal afferents are the main source for stimulus-induced CGRP release into jugular vein blood and CSF. Cephalalgia : An International Journal of Headache. 32: 659-67. PMID 22652383 DOI: 10.1177/0333102412447701  0.32
2012 Lauritzen M, Dirnagl U. Celebrating the 30th anniversary of our journal. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 1097. PMID 22569193 DOI: 10.1038/jcbfm.2012.61  0.32
2012 Dirnagl U, Fisher M. REPRINT: International, multicenter randomized preclinical trials in translational stroke research: it is time to act. Stroke; a Journal of Cerebral Circulation. 43: 1453-4. PMID 22535274 DOI: 10.1161/STROKEAHA.112.653709  0.32
2012 Dirnagl U, Fisher M. International, multicenter randomized preclinical trials in translational stroke research: it's time to act. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 933-5. PMID 22510602 DOI: 10.1038/jcbfm.2012.51  0.32
2012 Gertz K, Kronenberg G, Kälin RE, Baldinger T, Werner C, Balkaya M, Eom GD, Hellmann-Regen J, Kröber J, Miller KR, Lindauer U, Laufs U, Dirnagl U, Heppner FL, Endres M. Essential role of interleukin-6 in post-stroke angiogenesis. Brain : a Journal of Neurology. 135: 1964-80. PMID 22492561 DOI: 10.1093/brain/aws075  0.32
2012 Prüss H, Iggena D, Baldinger T, Prinz V, Meisel A, Endres M, Dirnagl U, Schwab JM. Evidence of intrathecal immunoglobulin synthesis in stroke: a cohort study. Archives of Neurology. 69: 714-7. PMID 22371852 DOI: 10.1001/archneurol.2011.3252  0.32
2012 Kopp MA, Liebscher T, Niedeggen A, Laufer S, Brommer B, Jungehulsing GJ, Strittmatter SM, Dirnagl U, Schwab JM. Small-molecule-induced Rho-inhibition: NSAIDs after spinal cord injury. Cell and Tissue Research. 349: 119-32. PMID 22350947 DOI: 10.1007/s00441-012-1334-7  0.32
2012 Mergenthaler P, Kahl A, Kamitz A, van Laak V, Stohlmann K, Thomsen S, Klawitter H, Przesdzing I, Neeb L, Freyer D, Priller J, Collins TJ, Megow D, Dirnagl U, Andrews DW, et al. Mitochondrial hexokinase II (HKII) and phosphoprotein enriched in astrocytes (PEA15) form a molecular switch governing cellular fate depending on the metabolic state. Proceedings of the National Academy of Sciences of the United States of America. 109: 1518-23. PMID 22233811 DOI: 10.1073/pnas.1108225109  0.32
2012 Zille M, Farr TD, Przesdzing I, Müller J, Sommer C, Dirnagl U, Wunder A. Visualizing cell death in experimental focal cerebral ischemia: promises, problems, and perspectives. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 213-31. PMID 22086195 DOI: 10.1038/jcbfm.2011.150  0.32
2012 Haeusler KG, Schmidt WU, Foehring F, Meisel C, Guenther C, Brunecker P, Kunze C, Helms T, Dirnagl U, Volk HD, Villringer A. Immune responses after acute ischemic stroke or myocardial infarction. International Journal of Cardiology. 155: 372-7. PMID 21078527 DOI: 10.1016/j.ijcard.2010.10.053  0.32
2011 Scherbakov N, Dirnagl U, Doehner W. Body weight after stroke: lessons from the obesity paradox. Stroke; a Journal of Cerebral Circulation. 42: 3646-50. PMID 21960580 DOI: 10.1161/STROKEAHA.111.619163  0.32
2011 Datwyler AL, Lättig-Tünnemann G, Yang W, Paschen W, Lee SL, Dirnagl U, Endres M, Harms C. SUMO2/3 conjugation is an endogenous neuroprotective mechanism. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 2152-9. PMID 21863037 DOI: 10.1038/jcbfm.2011.112  0.32
2011 Mergenthaler P, Dirnagl U. Protective conditioning of the brain: expressway or roadblock? The Journal of Physiology. 589: 4147-55. PMID 21708907 DOI: 10.1113/jphysiol.2011.209718  0.32
2011 Dirnagl U, Lauritzen M. Rotation of Editorial Board Members and new publication formats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1501. PMID 21587269 DOI: 10.1038/jcbfm.2011.71  0.32
2011 Macrez R, Ali C, Toutirais O, Le Mauff B, Defer G, Dirnagl U, Vivien D. Stroke and the immune system: from pathophysiology to new therapeutic strategies. The Lancet. Neurology. 10: 471-80. PMID 21511199 DOI: 10.1016/S1474-4422(11)70066-7  0.32
2011 Prüss H, Kopp MA, Brommer B, Gatzemeier N, Laginha I, Dirnagl U, Schwab JM. Non-resolving aspects of acute inflammation after spinal cord injury (SCI): indices and resolution plateau. Brain Pathology (Zurich, Switzerland). 21: 652-60. PMID 21418368 DOI: 10.1111/j.1750-3639.2011.00488.x  0.32
2011 Neeb L, Hellen P, Boehnke C, Hoffmann J, Schuh-Hofer S, Dirnagl U, Reuter U. IL-1β stimulates COX-2 dependent PGEâ‚‚ synthesis and CGRP release in rat trigeminal ganglia cells. Plos One. 6: e17360. PMID 21394197 DOI: 10.1371/journal.pone.0017360  0.32
2011 Engel O, Kolodziej S, Dirnagl U, Prinz V. Modeling stroke in mice - middle cerebral artery occlusion with the filament model. Journal of Visualized Experiments : Jove. PMID 21248698 DOI: 10.3791/2423  0.32
2011 Bahmani P, Schellenberger E, Klohs J, Steinbrink J, Cordell R, Zille M, Müller J, Harhausen D, Hofstra L, Reutelingsperger C, Farr TD, Dirnagl U, Wunder A. Visualization of cell death in mice with focal cerebral ischemia using fluorescent annexin A5, propidium iodide, and TUNEL staining. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1311-20. PMID 21245871 DOI: 10.1038/jcbfm.2010.233  0.32
2011 Dirnagl U, Lauritzen M. Improving the quality of biomedical research: guidelines for reporting experiments involving animals. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 989-90. PMID 21206506 DOI: 10.1038/jcbfm.2010.219  0.32
2011 Vesterinen HM, Vesterinen HV, Egan K, Deister A, Schlattmann P, Macleod MR, Dirnagl U. Systematic survey of the design, statistical analysis, and reporting of studies published in the 2008 volume of the Journal of Cerebral Blood Flow and Metabolism. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 1064-72. PMID 21157472 DOI: 10.1038/jcbfm.2010.217  0.32
2011 Ruscher K, Fernandes E, Capela JP, Bastos Mde L, Wieloch T, Dirnagl U, Meisel A, Carvalho F. Effect of 3,4-methylenedioxyamphetamine on dendritic spine dynamics in rat neocortical neurons--involvement of heat shock protein 27. Brain Research. 1370: 43-52. PMID 21075084 DOI: 10.1016/j.brainres.2010.11.022  0.32
2010 Kunz A, Dirnagl U, Mergenthaler P. Acute pathophysiological processes after ischaemic and traumatic brain injury. Best Practice & Research. Clinical Anaesthesiology. 24: 495-509. PMID 21619862 DOI: 10.1016/j.bpa.2010.10.001  0.32
2010 Piper S, Bahmani P, Klohs J, Bourayou R, Brunecker P, Müller J, Harhausen D, Lindauer U, Dirnagl U, Steinbrink J, Wunder A. Non-invasive surface-stripping for epifluorescence small animal imaging. Biomedical Optics Express. 1: 97-105. PMID 21258449 DOI: 10.1364/BOE.1.000097  0.32
2010 Fernández-Klett F, Offenhauser N, Dirnagl U, Priller J, Lindauer U. Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 107: 22290-5. PMID 21135230 DOI: 10.1073/pnas.1011321108  0.32
2010 Macleod MR, Petersson J, Norrving B, Hacke W, Dirnagl U, Wagner M, Schwab S. Hypothermia for Stroke: call to action 2010. International Journal of Stroke : Official Journal of the International Stroke Society. 5: 489-92. PMID 21086713 DOI: 10.1111/j.1747-4949.2010.00520.x  0.32
2010 Lindauer U, Dirnagl U, Füchtemeier M, Böttiger C, Offenhauser N, Leithner C, Royl G. Pathophysiological interference with neurovascular coupling - when imaging based on hemoglobin might go blind. Frontiers in Neuroenergetics. 2. PMID 20953238 DOI: 10.3389/fnene.2010.00025  0.32
2010 Leithner C, Müller S, Füchtemeier M, Lindauer U, Dirnagl U, Royl G. Determination of the brain-blood partition coefficient for water in mice using MRI. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1821-4. PMID 20842161 DOI: 10.1038/jcbfm.2010.160  0.32
2010 Dirnagl U. Oxygen maps in the brain. Nature Methods. 7: 697-9. PMID 20805799 DOI: 10.1038/nmeth0910-697  0.32
2010 Dirnagl U, Lauritzen M. Fighting publication bias: introducing the Negative Results section. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1263-4. PMID 20596038 DOI: 10.1038/jcbfm.2010.51  0.32
2010 Schlattmann P, Dirnagl U. Statistics in experimental cerebrovascular research: comparison of more than two groups with a continuous outcome variable. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1558-63. PMID 20571520 DOI: 10.1038/jcbfm.2010.95  0.32
2010 Harhausen D, Prinz V, Ziegler G, Gertz K, Endres M, Lehrach H, Gasque P, Botto M, Stahel PF, Dirnagl U, Nietfeld W, Trendelenburg G. CD93/AA4.1: a novel regulator of inflammation in murine focal cerebral ischemia. Journal of Immunology (Baltimore, Md. : 1950). 184: 6407-17. PMID 20439917 DOI: 10.4049/jimmunol.0902342  0.32
2010 Füchtemeier M, Leithner C, Offenhauser N, Foddis M, Kohl-Bareis M, Dirnagl U, Lindauer U, Royl G. Elevating intracranial pressure reverses the decrease in deoxygenated hemoglobin and abolishes the post-stimulus overshoot upon somatosensory activation in rats. Neuroimage. 52: 445-54. PMID 20420930 DOI: 10.1016/j.neuroimage.2010.04.237  0.32
2010 Harhausen D, Khojasteh U, Stahel PF, Morgan BP, Nietfeld W, Dirnagl U, Trendelenburg G. Membrane attack complex inhibitor CD59a protects against focal cerebral ischemia in mice. Journal of Neuroinflammation. 7: 15. PMID 20202211 DOI: 10.1186/1742-2094-7-15  0.32
2010 Schlattmann P, Dirnagl U. Statistics in experimental cerebrovascular research-comparison of two groups with a continuous outcome variable. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 474-9. PMID 20051976 DOI: 10.1038/jcbfm.2009.266  0.32
2010 Dirnagl U, Lauritzen M. If you have the science, we have the journal! Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 1. PMID 20046196 DOI: 10.1038/jcbfm.2009.252  0.32
2010 Lindauer U, Leithner C, Kaasch H, Rohrer B, Foddis M, Füchtemeier M, Offenhauser N, Steinbrink J, Royl G, Kohl-Bareis M, Dirnagl U. Neurovascular coupling in rat brain operates independent of hemoglobin deoxygenation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 757-68. PMID 20040927 DOI: 10.1038/jcbfm.2009.259  0.32
2010 Leithner C, Royl G, Offenhauser N, Füchtemeier M, Kohl-Bareis M, Villringer A, Dirnagl U, Lindauer U. Pharmacological uncoupling of activation induced increases in CBF and CMRO2. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 311-22. PMID 19794398 DOI: 10.1038/jcbfm.2009.211  0.32
2010 Dirnagl U, Lauritzen M. Journal of Cerebral Blood Flow and Metabolism: Editorial Journal of Cerebral Blood Flow and Metabolism. 30: 1411. DOI: 10.1038/jcbfm.2010.68  0.32
2010 Trendelenburg G, Dirnagl U. Glia and Stroke Encyclopedia of Neuroscience. 721-729. DOI: 10.1016/B978-008045046-9.01763-0  0.32
2010 Dirnagl U. Complexities, confounders, and challenges in experimental stroke research: A checklist for researchers and reviewers Neuromethods. 47: 263-277. DOI: 10.1007/978-1-60761-750-1_19  0.32
2010 Dirnagl U. Statistics in experimental stroke research: From sample size calculation to data description and significance testing Neuromethods. 47: 249-261. DOI: 10.1007/978-1-60761-750-1_18  0.32
2010 Dirnagl U. Quality control and standard operating procedures Neuromethods. 47: 239-248. DOI: 10.1007/978-1-60761-750-1_17  0.32
2010 Dirnagl U. Nature Geoscience: Preface Neuromethods. 47: vii-viii. DOI: 10.1007/978-1-60761-750-1  0.32
2010 Engel O, Dirnagl U, Meisel A. Infection - An amendment to the stroke model guidelines Journal of Experimental Stroke and Translational Medicine. 3: 29-32.  0.32
2009 Ziegler G, Prinz V, Albrecht MW, Harhausen D, Khojasteh U, Nacken W, Endres M, Dirnagl U, Nietfeld W, Trendelenburg G. Mrp-8 and -14 mediate CNS injury in focal cerebral ischemia. Biochimica Et Biophysica Acta. 1792: 1198-204. PMID 19835955 DOI: 10.1016/j.bbadis.2009.10.003  0.32
2009 Dirnagl U, Macleod MR. Stroke research at a road block: the streets from adversity should be paved with meta-analysis and good laboratory practice. British Journal of Pharmacology. 157: 1154-6. PMID 19664136 DOI: 10.1111/j.1476-5381.2009.00211.x  0.32
2009 Hoffmann J, Neeb L, Israel H, Dannenberg F, Triebe F, Dirnagl U, Reuter U. Intracisternal injection of inflammatory soup activates the trigeminal nerve system. Cephalalgia : An International Journal of Headache. 29: 1212-7. PMID 19558535 DOI: 10.1111/j.1468-2982.2009.01858.x  0.32
2009 Klohs J, Steinbrink J, Bourayou R, Mueller S, Cordell R, Licha K, Schirner M, Dirnagl U, Lindauer U, Wunder A. Near-infrared fluorescence imaging with fluorescently labeled albumin: a novel method for non-invasive optical imaging of blood-brain barrier impairment after focal cerebral ischemia in mice. Journal of Neuroscience Methods. 180: 126-32. PMID 19427539 DOI: 10.1016/j.jneumeth.2009.03.002  0.32
2009 Dreier JP, Major S, Manning A, Woitzik J, Drenckhahn C, Steinbrink J, Tolias C, Oliveira-Ferreira AI, Fabricius M, Hartings JA, Vajkoczy P, Lauritzen M, Dirnagl U, Bohner G, Strong AJ, et al. Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage. Brain : a Journal of Neurology. 132: 1866-81. PMID 19420089 DOI: 10.1093/brain/awp102  0.32
2009 Klohs J, Baeva N, Steinbrink J, Bourayou R, Boettcher C, Royl G, Megow D, Dirnagl U, Priller J, Wunder A. In vivo near-infrared fluorescence imaging of matrix metalloproteinase activity after cerebral ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1284-92. PMID 19417756 DOI: 10.1038/jcbfm.2009.51  0.32
2009 Royl G, Balkaya M, Lehmann S, Lehnardt S, Stohlmann K, Lindauer U, Endres M, Dirnagl U, Meisel A. Effects of the PDE5-inhibitor vardenafil in a mouse stroke model. Brain Research. 1265: 148-57. PMID 19368809 DOI: 10.1016/j.brainres.2009.01.061  0.32
2009 Dirnagl U, Becker K, Meisel A. Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use. The Lancet. Neurology. 8: 398-412. PMID 19296922 DOI: 10.1016/S1474-4422(09)70054-7  0.32
2009 Macleod MR, Fisher M, O'Collins V, Sena ES, Dirnagl U, Bath PM, Buchan A, van der Worp HB, Traystman RJ, Minematsu K, Donnan GA, Howells DW. Reprint: Good laboratory practice: preventing introduction of bias at the bench. International Journal of Stroke : Official Journal of the International Stroke Society. 4: 3-5. PMID 19236488 DOI: 10.1111/j.1747-4949.2009.00241.x  0.32
2009 Dirnagl U, Schwab JM. Brain-immune interactions in acute and chronic brain disorders. Neuroscience. 158: 969-71. PMID 19013503 DOI: 10.1016/j.neuroscience.2008.10.053  0.32
2009 Wunder A, Klohs J, Dirnagl U. Non-invasive visualization of CNS inflammation with nuclear and optical imaging. Neuroscience. 158: 1161-73. PMID 18983900 DOI: 10.1016/j.neuroscience.2008.10.005  0.32
2009 Macleod MR, Fisher M, O'Collins V, Sena ES, Dirnagl U, Bath PM, Buchan A, Buchan A, van der Worp HB, Traystman RJ, Minematsu K, Donnan GA, Howells DW. Reprint: Good laboratory practice: preventing introduction of bias at the bench. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 221-3. PMID 18797473 DOI: 10.1038/jcbfm.2008.101  0.32
2009 Endres M, Dirnagl U, Moskowitz MA. The ischemic cascade and mediators of ischemic injury. Handbook of Clinical Neurology. 92: 31-41. PMID 18790268 DOI: 10.1016/S0072-9752(08)01902-7  0.32
2009 Klehmet J, Harms H, Richter M, Prass K, Volk HD, Dirnagl U, Meisel A, Meisel C. Stroke-induced immunodepression and post-stroke infections: lessons from the preventive antibacterial therapy in stroke trial. Neuroscience. 158: 1184-93. PMID 18722511 DOI: 10.1016/j.neuroscience.2008.07.044  0.32
2009 Macleod MR, Fisher M, O'Collins V, Sena ES, Dirnagl U, Bath PM, Buchan A, van der Worp HB, Traystman R, Minematsu K, Donnan GA, Howells DW. Good laboratory practice: preventing introduction of bias at the bench. Stroke; a Journal of Cerebral Circulation. 40: e50-2. PMID 18703798 DOI: 10.1161/STROKEAHA.108.525386  0.32
2009 Endres M, Dreier JP, Kronenberg G, Meisel A, Dirnagl U. The Center for Stroke Research Berlin (CSB) | Das Centrum für Schlaganfallforschung Berlin (CSB) Neuroforum. 15: 132-135.  0.32
2008 Bourayou R, Boeth H, Benav H, Betz T, Lindauer U, Nierhaus T, Klohs J, Wunder A, Dirnagl U, Steinbrink J. Fluorescence tomography technique optimized for noninvasive imaging of the mouse brain. Journal of Biomedical Optics. 13: 041311. PMID 19021319 DOI: 10.1117/1.2968262  0.32
2008 Klohs J, Gräfe M, Graf K, Steinbrink J, Dietrich T, Stibenz D, Bahmani P, Kronenberg G, Harms C, Endres M, Lindauer U, Greger K, Stelzer EH, Dirnagl U, Wunder A. In vivo imaging of the inflammatory receptor CD40 after cerebral ischemia using a fluorescent antibody. Stroke; a Journal of Cerebral Circulation. 39: 2845-52. PMID 18635859 DOI: 10.1161/STROKEAHA.107.509844  0.32
2008 Macleod MR, van der Worp HB, Sena ES, Howells DW, Dirnagl U, Donnan GA. Evidence for the efficacy of NXY-059 in experimental focal cerebral ischaemia is confounded by study quality. Stroke; a Journal of Cerebral Circulation. 39: 2824-9. PMID 18635842 DOI: 10.1161/STROKEAHA.108.515957  0.32
2008 Steinbrink J, Liebert A, Wabnitz H, Macdonald R, Obrig H, Wunder A, Bourayou R, Betz T, Klohs J, Lindauer U, Dirnagl U, Villringer A. Towards noninvasive molecular fluorescence imaging of the human brain. Neuro-Degenerative Diseases. 5: 296-303. PMID 18520164 DOI: 10.1159/000135614  0.32
2008 Capela JP, Lautenschlager M, Dirnagl U, Bastos ML, Carvalho F, Meisel A. 5,7-Dihydroxitryptamine toxicity to serotonergic neurons in serum free raphe cultures. European Journal of Pharmacology. 588: 232-8. PMID 18519135 DOI: 10.1016/j.ejphar.2008.04.046  0.32
2008 Harms H, Prass K, Meisel C, Klehmet J, Rogge W, Drenckhahn C, Göhler J, Bereswill S, Göbel U, Wernecke KD, Wolf T, Arnold G, Halle E, Volk HD, Dirnagl U, et al. Preventive antibacterial therapy in acute ischemic stroke: a randomized controlled trial. Plos One. 3: e2158. PMID 18478129 DOI: 10.1371/journal.pone.0002158  0.32
2008 Dirnagl U, Meisel A. Endogenous neuroprotection: mitochondria as gateways to cerebral preconditioning? Neuropharmacology. 55: 334-44. PMID 18402985 DOI: 10.1016/j.neuropharm.2008.02.017  0.32
2008 Royl G, Füchtemeier M, Leithner C, Megow D, Offenhauser N, Steinbrink J, Kohl-Bareis M, Dirnagl U, Lindauer U. Hypothermia effects on neurovascular coupling and cerebral metabolic rate of oxygen. Neuroimage. 40: 1523-32. PMID 18343160 DOI: 10.1016/j.neuroimage.2008.01.041  0.32
2008 Petzold GC, Haack S, von Bohlen Und Halbach O, Priller J, Lehmann TN, Heinemann U, Dirnagl U, Dreier JP. Nitric oxide modulates spreading depolarization threshold in the human and rodent cortex. Stroke; a Journal of Cerebral Circulation. 39: 1292-9. PMID 18309156 DOI: 10.1161/STROKEAHA.107.500710  0.32
2008 Isaev NK, Stelmashook EV, Dirnagl U, Plotnikov EY, Kuvshinova EA, Zorov DB. Mitochondrial free radical production induced by glucose deprivation in cerebellar granule neurons. Biochemistry. BiokhimiiÍ¡A. 73: 149-55. PMID 18298370 DOI: 10.1007/s10541-008-2005-x  0.32
2008 Endres M, Engelhardt B, Koistinaho J, Lindvall O, Meairs S, Mohr JP, Planas A, Rothwell N, Schwaninger M, Schwab ME, Vivien D, Wieloch T, Dirnagl U. Improving outcome after stroke: overcoming the translational roadblock. Cerebrovascular Diseases (Basel, Switzerland). 25: 268-78. PMID 18292653 DOI: 10.1159/000118039  0.32
2008 Lopes MA, Meisel A, Dirnagl U, Carvalho FD, Bastos Mde L. Doxorubicin induces biphasic neurotoxicity to rat cortical neurons. Neurotoxicology. 29: 286-93. PMID 18258305 DOI: 10.1016/j.neuro.2007.12.003  0.32
2008 Crossley NA, Sena E, Goehler J, Horn J, van der Worp B, Bath PM, Macleod M, Dirnagl U. Empirical evidence of bias in the design of experimental stroke studies: a metaepidemiologic approach. Stroke; a Journal of Cerebral Circulation. 39: 929-34. PMID 18239164 DOI: 10.1161/STROKEAHA.107.498725  0.32
2008 Leithner C, Gertz K, Schröck H, Priller J, Prass K, Steinbrink J, Villringer A, Endres M, Lindauer U, Dirnagl U, Royl G. A flow sensitive alternating inversion recovery (FAIR)-MRI protocol to measure hemispheric cerebral blood flow in a mouse stroke model. Experimental Neurology. 210: 118-27. PMID 18037417 DOI: 10.1016/j.expneurol.2007.10.003  0.32
2008 Haeusler KG, Schmidt WU, Föhring F, Meisel C, Helms T, Jungehulsing GJ, Nolte CH, Schmolke K, Wegner B, Meisel A, Dirnagl U, Villringer A, Volk HD. Cellular immunodepression preceding infectious complications after acute ischemic stroke in humans. Cerebrovascular Diseases (Basel, Switzerland). 25: 50-8. PMID 18033958 DOI: 10.1159/000111499  0.32
2008 Prüss H, Prass K, Ghaeni L, Milosevic M, Muselmann C, Freyer D, Royl G, Reuter U, Baeva N, Dirnagl U, Meisel A, Priller J. Inducible nitric oxide synthase does not mediate brain damage after transient focal cerebral ischemia in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 526-39. PMID 17851454 DOI: 10.1038/sj.jcbfm.9600550  0.32
2008 Donnan GA, Adams R, Bacellar A, Baron JC, Bath P, Benavente O, Bladin C, Bornstein N, Brainin M, Chambers B, Chen C, Csiba L, Culebras A, Davalos A, Davis S, ... ... Dirnagl U, et al. Editorial International Journal of Stroke. 3: 1-2. DOI: 10.1111/j.1747-4949.2008.00166.x  0.32
2007 Kunte H, Schmidt S, Eliasziw M, del Zoppo GJ, Simard JM, Masuhr F, Weih M, Dirnagl U. Sulfonylureas improve outcome in patients with type 2 diabetes and acute ischemic stroke. Stroke; a Journal of Cerebral Circulation. 38: 2526-30. PMID 17673715 DOI: 10.1161/STROKEAHA.107.482216  0.32
2007 Braun JS, Prass K, Dirnagl U, Meisel A, Meisel C. Protection from brain damage and bacterial infection in murine stroke by the novel caspase-inhibitor Q-VD-OPH. Experimental Neurology. 206: 183-91. PMID 17585906 DOI: 10.1016/j.expneurol.2007.03.032  0.32
2007 Capela JP, Macedo C, Branco PS, Ferreira LM, Lobo AM, Fernandes E, Remião F, Bastos ML, Dirnagl U, Meisel A, Carvalho F. Neurotoxicity mechanisms of thioether ecstasy metabolites Neuroscience. 146: 1743-1757. PMID 17467183 DOI: 10.1016/j.neuroscience.2007.03.028  0.32
2007 Harms C, Albrecht K, Harms U, Seidel K, Hauck L, Baldinger T, Hübner D, Kronenberg G, An J, Ruscher K, Meisel A, Dirnagl U, von Harsdorf R, Endres M, Hörtnagl H. Phosphatidylinositol 3-Akt-kinase-dependent phosphorylation of p21(Waf1/Cip1) as a novel mechanism of neuroprotection by glucocorticoids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4562-71. PMID 17460069 DOI: 10.1523/JNEUROSCI.5110-06.2007  0.32
2007 Ruscher K, Rzeczinski S, Thein E, Freyer D, Victorov IV, Lam TT, Dirnagl U. Neuroprotective effects of the beta-carboline abecarnil studied in cultured cortical neurons and organotypic retinal cultures. Neuropharmacology. 52: 1488-95. PMID 17449066 DOI: 10.1016/j.neuropharm.2007.02.006  0.32
2007 Dirnagl U, Klehmet J, Braun JS, Harms H, Meisel C, Ziemssen T, Prass K, Meisel A. Stroke-induced immunodepression: Experimental evidence and clinical relevance Stroke. 38: 770-773. PMID 17261736 DOI: 10.1161/01.STR.0000251441.89665.bc  0.32
2007 Dreier JP, Kleeberg J, Alam M, Major S, Kohl-Bareis M, Petzold GC, Victorov I, Dirnagl U, Obrenovitch TP, Priller J. Endothelin-1-induced spreading depression in rats is associated with a microarea of selective neuronal necrosis Experimental Biology and Medicine. 232: 204-213. PMID 17259327  0.32
2007 Prass K, Royl G, Lindauer U, Freyer D, Megow D, Dirnagl U, Stöckler-Ipsiroglu G, Wallimann T, Priller J. Improved reperfusion and neuroprotection by creatine in a mouse model of stroke Journal of Cerebral Blood Flow and Metabolism. 27: 452-459. PMID 16773141 DOI: 10.1038/sj.jcbfm.9600351  0.32
2007 Offenhauser N, Royl G, Leithner C, Dirnagl U, Lindauer U. Sustained alteration of neurometabolic, -vascular coupling by cortical spreading depression in rat somatosensory cortex Journal of Cerebral Blood Flow and Metabolism. 27: BO13-07.  0.32
2007 Fernandez-Klett F, Offenhauser N, Dirnagl U, Priller J, Lindauer U. Evidence for capillary vasoconstriction in cerebral cortex of mice Journal of Cerebral Blood Flow and Metabolism. 27: BO12-04.  0.32
2006 Gertz K, Priller J, Kronenberg G, Fink KB, Winter B, Schröck H, Ji S, Milosevic M, Harms C, Böhm M, Dirnagl U, Laufs U, Endres M. Physical activity improves long-term stroke outcome via endothelial nitric oxide synthase-dependent augmentation of neovascularization and cerebral blood flow Circulation Research. 99: 1132-1140. PMID 17038638 DOI: 10.1161/01.RES.0000250175.14861.77  0.32
2006 Royl G, Leithner C, Sellien H, Müller JP, Megow D, Offenhauser N, Steinbrink J, Kohl-Bareis M, Dirnagl U, Lindauer U. Functional imaging with laser speckle contrast analysis: vascular compartment analysis and correlation with laser Doppler flowmetry and somatosensory evoked potentials. Brain Research. 1121: 95-103. PMID 17030028 DOI: 10.1016/j.brainres.2006.08.125  0.32
2006 Rzeczinski S, Victorov IV, Lyjin AA, Aleksandrova OP, Harms C, Kronenberg G, Freyer D, Scheibe F, Priller J, Endres M, Dirnagl U. Roller culture of free-floating retinal slices: A new system of organotypic cultures of adult rat retina Ophthalmic Research. 38: 263-269. PMID 16974126 DOI: 10.1159/000095768  0.32
2006 Stroh A, Zimmer C, Werner N, Gertz K, Weir K, Kronenberg G, Steinbrink J, Mueller S, Sieland K, Dirnagl U, Nickenig G, Endres M. Tracking of systemically administered mononuclear cells in the ischemic brain by high-field magnetic resonance imaging Neuroimage. 33: 886-897. PMID 16973381 DOI: 10.1016/j.neuroimage.2006.07.009  0.32
2006 Klohs J, Steinbrink J, Nierhaus T, Bourayou R, Lindauer U, Bahmani P, Dirnagl U, Wunder A. Noninvasive near-infrared imaging of fluorochromes within the brain of live mice: an in vivo phantom study Molecular Imaging : Official Journal of the Society For Molecular Imaging. 5: 180-187. PMID 16954033  0.32
2006 Prass K, Braun JS, Dirnagl U, Meisel C, Meisel A. Stroke propagates bacterial aspiration to pneumonia in a model of cerebral ischemia Stroke. 37: 2607-2612. PMID 16946159 DOI: 10.1161/01.STR.0000240409.68739.2b  0.32
2006 Scheckenbach KEL, Dreier JP, Dirnagl U, Lindauer U. Impaired cerebrovascular reactivity after cortical spreading depression in rats: Restoration by nitric oxide or cGMP Experimental Neurology. 202: 449-455. PMID 16920100 DOI: 10.1016/j.expneurol.2006.07.007  0.32
2006 Meairs S, Wahlgren N, Dirnagl U, Lindvall O, Rothwell P, Baron JC, Hossmann K, Engelhardt B, Ferro J, McCulloch J, Kaste M, Endres M, Koistinaho J, Planas A, Vivien D, et al. Stroke research priorities for the next decade--A representative view of the European scientific community. Cerebrovascular Diseases (Basel, Switzerland). 22: 75-82. PMID 16790993 DOI: 10.1159/000093098  0.32
2006 Dirnagl U. Bench to bedside: The quest for quality in experimental stroke research Journal of Cerebral Blood Flow and Metabolism. 26: 1465-1478. PMID 16525413 DOI: 10.1038/sj.jcbfm.9600298  0.32
2006 Capela JP, Ruscher K, Lautenschlager M, Freyer D, Dirnagl U, Gaio AR, Bastos ML, Meisel A, Carvalho F. Ecstasy-induced cell death in cortical neuronal cultures is serotonin 2A-receptor-dependent and potentiated under hyperthermia Neuroscience. 139: 1069-1081. PMID 16504407 DOI: 10.1016/j.neuroscience.2006.01.007  0.32
2006 Schuh-Hofer S, Tayefeh M, Reuter U, Dirnagl U, Arnold G. Effects of parecoxib on plasma protein extravasation and c-fos expression in the rat Headache. 46: 276-285. PMID 16492237 DOI: 10.1111/j.1526-4610.2006.00332.x  0.32
2005 Petzold GC, Scheibe F, Braun JS, Freyer D, Priller J, Dirnagl U, Dreier JP. Nitric oxide modulates calcium entry through P/Q-type calcium channels and N-methyl-d-aspartate receptors in rat cortical neurons Brain Research. 1063: 9-14. PMID 16274675 DOI: 10.1016/j.brainres.2005.09.048  0.32
2005 Meisel C, Schwab JM, Prass K, Meisel A, Dirnagl U. Central nervous system injury-induced immune deficiency syndrome Nature Reviews Neuroscience. 6: 775-786. PMID 16163382 DOI: 10.1038/nrn1765  0.32
2005 Windmüller O, Lindauer U, Foddis M, Einhäupl KM, Dirnagl U, Heinemann U, Dreier JP. Ion changes in spreading ischaemia induce rat middle cerebral artery constriction in the absence of NO. Brain : a Journal of Neurology. 128: 2042-51. PMID 15901647 DOI: 10.1093/brain/awh545  0.32
2005 Petzold GC, Windmüller O, Haack S, Major S, Buchheim K, Megow D, Gabriel S, Lehmann TN, Drenckhahn C, Peters O, Meierkord H, Heinemann U, Dirnagl U, Dreier JP. Increased extracellular K+ concentration reduces the efficacy of N-methyl-D-aspartate receptor antagonists to block spreading depression-like depolarizations and spreading ischemia. Stroke; a Journal of Cerebral Circulation. 36: 1270-7. PMID 15879337 DOI: 10.1161/01.STR.0000166023.51307.e0  0.32
2005 Nedergaard M, Dirnagl U. Role of glial cells in cerebral ischemia. Glia. 50: 281-6. PMID 15846807 DOI: 10.1002/glia.20205  0.32
2005 Trendelenburg G, Dirnagl U. Neuroprotective role of astrocytes in cerebral ischemia: Focus on ischemic preconditioning Glia. 50: 307-320. PMID 15846804 DOI: 10.1002/glia.20204  0.32
2005 Bösel J, Gandor F, Harms C, Synowitz M, Harms U, Djoufack PC, Megow D, Dirnagl U, Hörtnagl H, Fink KB, Endres M. Neuroprotective effects of atorvastatin against glutamate-induced excitotoxicity in primary cortical neurones Journal of Neurochemistry. 92: 1386-1398. PMID 15748157 DOI: 10.1111/j.1471-4159.2004.02980.x  0.32
2005 Offenhauser N, Zinck T, Hoffmann J, Schiemann K, Schuh-Hofer S, Rohde W, Arnold G, Dirnagl U, Jansen-Olesen I, Reuter U. CGRP release and c-fos expression within trigeminal nucleus caudalis of the rat following glyceryltrinitrate infusion Cephalalgia. 25: 225-236. PMID 15689199 DOI: 10.1111/j.1468-2982.2004.00845.x  0.32
2005 Bechmann I, Goldmann J, Kovac AD, Kwidzinski E, Simbürger E, Naftolin F, Dirnagl U, Nitsch R, Priller J. Circulating monocytic cells infiltrate layers of anterograde axonal degeneration where they transform into microglia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 647-9. PMID 15671154 DOI: 10.1096/fj.04-2599fje  0.32
2005 Li J, Culman J, Hörtnagl H, Zhao Y, Gerova N, Timm M, Blume A, Zimmermann M, Seidel K, Dirnagl U, Unger T. Angiotensin AT2 receptor protects against cerebral ischemia-induced neuronal injury Faseb Journal. 19: 617-619. PMID 15665034 DOI: 10.1096/fj.04-2960fje  0.32
2005 Kohl-Bareis M, Leithner C, Sellien H, Gürtler R, Geraskin D, Rohrer B, Royl G, Dirnagl U, Lindauer U. System for the measurement of blood flow and oxygenation in tissue applied to neurovascular coupling in brain Progress in Biomedical Optics and Imaging - Proceedings of Spie. 5859: 1-7.  0.32
2004 Dreier JP, Tille K, Dirnagl U. Partial antagonistic effect of adenosine on inverse coupling between spreading neuronal activation and cerebral blood flow in rats Neurocritical Care. 1: 85-94. PMID 16174901 DOI: 10.1385/NCC:1:1:85  0.32
2004 Mergenthaler P, Dirnagl U, Meisel A. Pathophysiology of stroke: Lessons from animal models Metabolic Brain Disease. 19: 151-167. PMID 15554412 DOI: 10.1023/B:MEBR.0000043966.46964.e6  0.32
2004 Viktorov IV, Lyzhin AA, Aleksandrova OP, Frayer D, Dirnagl U. Roller organotypic cultures of postnatal rat retina Bulletin of Experimental Biology and Medicine. 137: 419-422. PMID 15452619 DOI: 10.1023/B:BEBM.0000035147.97443.da  0.32
2004 Endres M, Biniszkiewicz D, Sobol RW, Harms C, Ahmadi M, Lipski A, Katchanov J, Mergenthaler P, Dirnagl U, Wilson SH, Meisel A, Jaenisch R. Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. The Journal of Clinical Investigation. 113: 1711-21. PMID 15199406 DOI: 10.1172/JCI20926  0.32
2004 Angstwurm K, Hanisch UK, Gassemi T, Bille MB, Prinz M, Dirnagl U, Kettenmann H, Weber JR. Tyrosine kinase inhibition reduces inflammation in the acute stage of experimental pneumococcal meningitis. Infection and Immunity. 72: 3294-8. PMID 15155632 DOI: 10.1128/IAI.72.6.3294-3298.2004  0.32
2004 Seitz I, Dirnagl U, Lindauer U. Impaired Vascular Reactivity of Isolated Rat Middle Cerebral Artery after Cortical Spreading Depression in Vivo Journal of Cerebral Blood Flow and Metabolism. 24: 526-530. PMID 15129184  0.32
2004 Dirnagl U. Inflammation in stroke: the good, the bad, and the unknown Ernst Schering Research Foundation Workshop. 87-99. PMID 15032055  0.32
2004 Schulz JG, Bösel J, Stoeckel M, Megow D, Dirnagl U, Endres M. HMG-CoA reductase inhibition causes neurite loss by interfering with geranylgeranylpyrophosphate synthesis. Journal of Neurochemistry. 89: 24-32. PMID 15030386 DOI: 10.1046/j.1471-4159.2003.02305.x  0.32
2004 Harms C, Bösel J, Lautenschlager M, Harms U, Braun JS, Hörtnagl H, Dirnagl U, Kwiatkowski DJ, Fink K, Endres M. Neuronal gelsolin prevents apoptosis by enhancing actin depolymerization Molecular and Cellular Neuroscience. 25: 69-82. PMID 14962741 DOI: 10.1016/j.mcn.2003.09.012  0.32
2004 Meisel C, Prass K, Braun J, Victorov I, Wolf T, Megow D, Halle E, Volk HD, Dirnagl U, Meisel A. Preventive Antibacterial Treatment Improves the General Medical and Neurological Outcome in A Mouse Model of Stroke Stroke. 35: 2-6. PMID 14684767 DOI: 10.1161/01.STR.0000109041.89959.4C  0.32
2004 Winter B, Bert B, Fink H, Dirnagl U, Endres M. Dysexecutive Syndrome after Mild Cerebral Ischemia? Mice Learn Normally but Have Deficits in Strategy Switching Stroke. 35: 191-195. PMID 14671235 DOI: 10.1161/01.STR.0000107188.29688.2C  0.32
2004 Kleeberg J, Petzold GC, Major S, Dirnagl U, Dreier JP. ET-1 induces cortical spreading depression via activation of the ET A receptor/phospholipase C pathway in vivo American Journal of Physiology - Heart and Circulatory Physiology. 286: H1339-H1346. PMID 14656702 DOI: 10.1152/ajpheart.00227.2003  0.32
2004 Harms H, Prass K, Dirnagl U, Meisel A. The Pathophysiological Basis of Stroke Therapy: A Critical Review of the Experimental and Clinical Evidence | Therapierelevante Pathophysiologie des Akuten Ischämischen Schlaganfalls: Was ist Gesichert? Aktuelle Neurologie. 31: 113-121. DOI: 10.1055/s-2003-812643  0.32
2004 Dirnagl U. Cerebroprotection against cerebral ischemia - Fact and fiction Journal Fur Anasthesie Und Intensivbehandlung. 11: 26.  0.32
2003 Katchanov J, Waeber C, Gertz K, Gietz A, Winter B, Brück W, Dirnagl U, Veh RW, Endres M. Selective Neuronal Vulnerability Following Mild Focal Brain Ischemia in the Mouse Brain Pathology. 13: 452-464. PMID 14655751  0.32
2003 Schuh-Hofer S, Boehnke C, Reuter U, Siekmann W, Lindauer U, Arnold G, Dirnagl U. A fluorescence-based method to assess plasma protein extravasation in rat dura mater using confocal laser scanning microscopy Brain Research Protocols. 12: 77-82. PMID 14613808 DOI: 10.1016/j.brainresprot.2003.08.003  0.32
2003 Petzold GC, Einhäupl KM, Dirnagl U, Dreier JP. Ischemia Triggered by Spreading Neuronal Activation Is Induced by Endothelin-1 and Hemoglobin in the Subarachnoid Space Annals of Neurology. 54: 591-598. PMID 14595648 DOI: 10.1002/ana.10723  0.32
2003 Endres M, Gertz K, Lindauer U, Katchanov J, Schultze J, Schröck H, Nickenig G, Kuschinsky W, Dirnagl U, Laufs U. Mechanisms of stroke protection by physical activity. Annals of Neurology. 54: 582-90. PMID 14595647 DOI: 10.1002/ana.10722  0.32
2003 Lindauer U, Vogt J, Schuh-Hofer S, Dreier JP, Dirnagl U. Cerebrovascular vasodilation to extraluminal acidosis occurs via combined activation of ATP-sensitive and Ca2+-activated potassium channels Journal of Cerebral Blood Flow and Metabolism. 23: 1227-1238. PMID 14526233  0.32
2003 Prass K, Meisel C, Höflich C, Braun J, Halle E, Wolf T, Ruscher K, Victorov IV, Priller J, Dirnagl U, Volk HD, Meisel A. Stroke-induced immunodeficiency promotes spontaneous bacterial infections and is mediated by sympathetic activation reversal by poststroke T helper cell Type 1-like immunostimulation Journal of Experimental Medicine. 198: 725-736. PMID 12939340 DOI: 10.1084/jem.20021098  0.32
2003 Wehner T, Böntert M, Eyüpoglu I, Prass K, Prinz M, Klett FF, Heinze M, Bechmann I, Nitsch R, Kirchhoff F, Kettenmann H, Dirnagl U, Priller J. Bone marrow-derived cells expressing green fluorescent protein under the control of the glial fibrillary acidic protein promoter do not differentiate into astrocytes in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 5004-11. PMID 12832523  0.32
2003 Prass K, Scharff A, Ruscher K, Löwl D, Muselmann C, Victorov I, Kapinya K, Dirnagl U, Meisel A. Hypoxia-induced stroke tolerance in the mouse is mediated by erythropoietin. Stroke; a Journal of Cerebral Circulation. 34: 1981-6. PMID 12829864 DOI: 10.1161/01.STR.0000080381.76409.B2  0.32
2003 Kannbley U, Kapinya K, Dirnagl U, Trendelenburg G. Improved protocol for SAGE tag-to-gene allocation Biotechniques. 34: 1212-1219. PMID 12813889  0.32
2003 Strehlow K, Werner N, Berweiler J, Link A, Dirnagl U, Priller J, Laufs K, Ghaeni L, Milosevic M, Böhm M, Nickenig G. Estrogen increases bone marrow-derived endothelial progenitor cell production and diminishes neointima formation Circulation. 107: 3059-3065. PMID 12810616 DOI: 10.1161/01.CIR.0000077911.81151.30  0.32
2003 Lindauer U, Gethmann J, Kühl M, Kohl-Bareis M, Dirnagl U. Neuronal activity-induced changes of local cerebral microvascular blood oxygenation in the rat: Effect of systemic hyperoxia or hypoxia Brain Research. 975: 135-140. PMID 12763601 DOI: 10.1016/S0006-8993(03)02602-7  0.32
2003 Dirnagl U, Simon RP, Hallenbeck JM. Ischemic tolerance and endogenous neuroprotection Trends in Neurosciences. 26: 248-254. PMID 12744841 DOI: 10.1016/S0166-2236(03)00071-7  0.32
2003 Kapinya KJ, Harms U, Harms C, Blei K, Katchanov J, Dirnagl U, Hörtnagl H. Role of NAD(P)H:quinone oxidoreductase in the progression of neuronal cell death in vitro and following cerebral ischaemia in vivo Journal of Neurochemistry. 84: 1028-1039. PMID 12603827 DOI: 10.1046/j.1471-4159.2003.01601.x  0.32
2003 Gertz K, Laufs U, Lindauer U, Nickenig G, Böhm M, Dirnagl U, Endres M. Withdrawal of statin treatment abrogates stroke protection in mice Stroke. 34: 551-557. PMID 12574574 DOI: 10.1161/01.STR.0000054055.28435.BF  0.32
2002 Endres M, Dirnagl U. Ischemia and stroke Advances in Experimental Medicine and Biology. 513: 455-473. PMID 12575832  0.32
2002 Ruscher K, Freyer D, Karsch M, Isaev N, Megow D, Sawitzki B, Priller J, Dirnagl U, Meisel A. Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: Evidence from an in vitro model Journal of Neuroscience. 22: 10291-10301. PMID 12451129  0.32
2002 Dreier JP, Sakowitz OW, Harder A, Zimmer C, Dirnagl U, Valdueza JM, Unterberg AW. Focal laminar cortical MR signal abnormalities after subarachnoid hemorrhage Annals of Neurology. 52: 825-829. PMID 12447937 DOI: 10.1002/ana.10383  0.32
2002 Dreier JP, Windmüller O, Petzold G, Lindauer U, Einhäupl KM, Dirnagl U, Loch Macdonald R, Dempsey RJ, Selman WR, Mocco J, Connolly ES. Ischemia triggered by red blood cell products in the subarachnoid space is inhibited by nimodipine administration or moderate volume expansion/hemodilution in rats Neurosurgery. 51: 1457-1467. PMID 12445352 DOI: 10.1097/00006123-200212000-00017  0.32
2002 Werner N, Priller J, Laufs U, Endres M, Böhm M, Dirnagl U, Nickenig G. Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: Effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1567-1572. PMID 12377731 DOI: 10.1161/01.ATV.0000036417.43987.D8  0.32
2002 Hoffmann O, Keilwerth N, Bille MB, Reuter U, Angstwurm K, Schumann RR, Dirnagl U, Weber JR. Triptans reduce the inflammatory response in bacterial meningitis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 988-96. PMID 12172384 DOI: 10.1097/00004647-200208000-00010  0.32
2002 Kapinya KJ, Prass K, Dirnagl U. Isoflurane induced prolonged protection against cerebral ischemia in mice: A redox sensitive mechanism? Neuroreport. 13: 1431-1435. PMID 12167768  0.32
2002 Isaev NK, Stelmashook EV, Dirnagl U, Andreeva NA, Manuhova L, Vorobjev VS, Sharonova IN, Skrebitsky VG, Victorov IV, Katchanov J, Weih M, Zorov DB. Neuroprotective effects of the antifungal drug clotrimazole Neuroscience. 113: 47-53. PMID 12123683 DOI: 10.1016/S0306-4522(02)00164-1  0.32
1998 Kohl M, Lindauer U, Dirnagl U, Villringer A. Separation of changes in light scattering and chromophore concentrations during cortical spreading depression in rats. Optics Letters. 23: 555-7. PMID 18084575  0.32
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