Ron Kuczenski - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Drugs of addiction

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Le Cozannet R, Markou A, Kuczenski R. Extended-access, but not limited-access, methamphetamine self-administration induces behavioral and nucleus accumbens dopamine response changes in rats. The European Journal of Neuroscience. 38: 3487-95. PMID 24112125 DOI: 10.1111/ejn.12361  1
2013 Laćan G, Hadamitzky M, Kuczenski R, Melega WP. Alterations in the striatal dopamine system during intravenous methamphetamine exposure: Effects of contingent and noncontingent administration Synapse. 67: 476-488. PMID 23417852 DOI: 10.1002/syn.21654  1
2012 Hadamitzky M, McCunney S, Markou A, Kuczenski R. Development of stereotyped behaviors during prolonged escalation of methamphetamine self-administration in rats. Psychopharmacology. 223: 259-69. PMID 22526541 DOI: 10.1007/s00213-012-2713-1  1
2012 Amitai N, Kuczenski R, Behrens MM, Markou A. Repeated phencyclidine administration alters glutamate release and decreases GABA markers in the prefrontal cortex of rats. Neuropharmacology. 62: 1422-31. PMID 21238466 DOI: 10.1016/j.neuropharm.2011.01.008  1
2011 Le-Niculescu H, Balaraman Y, Patel SD, Ayalew M, Gupta J, Kuczenski R, Shekhar A, Schork N, Geyer MA, Niculescu AB. Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms. Translational Psychiatry. 1: e9. PMID 22832404 DOI: 10.1038/tp.2011.9  1
2011 Le-Niculescu H, Case NJ, Hulvershorn L, Patel SD, Bowker D, Gupta J, Bell R, Edenberg HJ, Tsuang MT, Kuczenski R, Geyer MA, Rodd ZA, Niculescu AB. Convergent functional genomic studies of ω-3 fatty acids in stress reactivity, bipolar disorder and alcoholism. Translational Psychiatry. 1: e4. PMID 22832392 DOI: 10.1038/tp.2011.1  1
2011 D'Souza MS, Liechti ME, Ramirez-Niño AM, Kuczenski R, Markou A. The metabotropic glutamate 2/3 receptor agonist LY379268 blocked nicotine-induced increases in nucleus accumbens shell dopamine only in the presence of a nicotine-associated context in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2111-24. PMID 21654734 DOI: 10.1038/npp.2011.103  1
2011 Hadamitzky M, Markou A, Kuczenski R. Extended access to methamphetamine self-administration affects sensorimotor gating in rats. Behavioural Brain Research. 217: 386-90. PMID 21070821 DOI: 10.1016/j.bbr.2010.11.009  1
2010 Berman SM, Kuczenski R, McCracken JT, London ED. Potential adverse effects of amphetamine treatment on brain and behavior: A review (Molecular Psychiatry (2009) 14 (123-142) DOI: 10.1038/mp.2008.90) Molecular Psychiatry. 15: 1121. DOI: 10.1038/mp.2010.39  1
2010 Kuczenski R. Amphetamines Encyclopedia of Neuroscience. 319-323. DOI: 10.1016/B978-008045046-9.01142-6  1
2009 McGrath CL, Glatt SJ, Sklar P, Le-Niculescu H, Kuczenski R, Doyle AE, Biederman J, Mick E, Faraone SV, Niculescu AB, Tsuang MT. Evidence for genetic association of RORB with bipolar disorder. Bmc Psychiatry. 9: 70. PMID 19909500 DOI: 10.1186/1471-244X-9-70  1
2009 Kuczenski R, Segal DS, Melega WP, Lacan G, McCunney SJ. Human methamphetamine pharmacokinetics simulated in the rat: behavioral and neurochemical effects of a 72-h binge. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2430-41. PMID 19571794 DOI: 10.1038/npp.2009.73  1
2009 Le-Niculescu H, Patel SD, Bhat M, Kuczenski R, Faraone SV, Tsuang MT, McMahon FJ, Schork NJ, Nurnberger JI, Niculescu AB. Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 155-81. PMID 19025758 DOI: 10.1002/ajmg.b.30887  1
2009 Berman SM, Kuczenski R, McCracken JT, London ED. Potential adverse effects of amphetamine treatment on brain and behavior: a review. Molecular Psychiatry. 14: 123-42. PMID 18698321 DOI: 10.1038/mp.2008.90  1
2008 Le-Niculescu H, McFarland MJ, Ogden CA, Balaraman Y, Patel S, Tan J, Rodd ZA, Paulus M, Geyer MA, Edenberg HJ, Glatt SJ, Faraone SV, Nurnberger JI, Kuczenski R, Tsuang MT, et al. Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 134-66. PMID 18247375 DOI: 10.1002/ajmg.b.30707  1
2007 Le-Niculescu H, McFarland MJ, Mamidipalli S, Ogden CA, Kuczenski R, Kurian SM, Salomon DR, Tsuang MT, Nurnberger JI, Niculescu AB. Convergent Functional Genomics of bipolar disorder: from animal model pharmacogenomics to human genetics and biomarkers. Neuroscience and Biobehavioral Reviews. 31: 897-903. PMID 17614132 DOI: 10.1016/j.neubiorev.2007.05.008  1
2007 Kuczenski R, Everall IP, Crews L, Adame A, Grant I, Masliah E. Escalating dose-multiple binge methamphetamine exposure results in degeneration of the neocortex and limbic system in the rat Experimental Neurology. 207: 42-51. PMID 17603040 DOI: 10.1016/j.expneurol.2007.05.023  1
2007 Clark RE, Kuczenski R, Segal DS. Escalating dose, multiple binge methamphetamine regimen does not impair recognition memory in rats. Synapse (New York, N.Y.). 61: 515-22. PMID 17415795 DOI: 10.1002/syn.20397  1
2007 Le-Niculescu H, Balaraman Y, Patel S, Tan J, Sidhu K, Jerome RE, Edenberg HJ, Kuczenski R, Geyer MA, Nurnberger JI, Faraone SV, Tsuang MT, Niculescu AB. Towards understanding the schizophrenia code: an expanded convergent functional genomics approach. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 129-58. PMID 17266109 DOI: 10.1002/ajmg.b.30481  1
2006 O'Neil ML, Kuczenski R, Segal DS, Cho AK, Lacan G, Melega WP. Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge. Synapse (New York, N.Y.). 60: 465-73. PMID 16897726 DOI: 10.1002/syn.20320  1
2006 Shilling PD, Kuczenski R, Segal DS, Barrett TB, Kelsoe JR. Differential regulation of immediate-early gene expression in the prefrontal cortex of rats with a high vs low behavioral response to methamphetamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2359-67. PMID 16855532 DOI: 10.1038/sj.npp.1301162  1
2006 Swerdlow NR, Shoemaker JM, Kuczenski R, Bongiovanni MJ, Neary AC, Tochen LS, Saint Marie RL. Forebrain D1 function and sensorimotor gating in rats: effects of D1 blockade, frontal lesions and dopamine denervation. Neuroscience Letters. 402: 40-5. PMID 16644125 DOI: 10.1016/j.neulet.2006.03.060  1
2006 Segal DS, Kuczenski R. Human methamphetamine pharmacokinetics simulated in the rat: single daily intravenous administration reveals elements of sensitization and tolerance. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 941-55. PMID 16123749 DOI: 10.1038/sj.npp.1300865  1
2006 Judd LL, Kuczenski R, Schuckit M, Swerdlow N. In memorium: Professor David S Segal Neuropsychopharmacology. 31: 2331. DOI: 10.1038/sj.npp.1301158  1
2005 Bertsch B, Ogden CA, Sidhu K, Le-Niculescu H, Kuczenski R, Niculescu AB. Convergent functional genomics: A Bayesian candidate gene identification approach for complex disorders Methods. 37: 274-279. PMID 16308156 DOI: 10.1016/j.ymeth.2005.03.012  1
2005 Segal DS, Kuczenski R, O'Neil ML, Melega WP, Cho AK. Prolonged exposure of rats to intravenous methamphetamine: behavioral and neurochemical characterization. Psychopharmacology. 180: 501-12. PMID 15959831 DOI: 10.1007/s00213-005-2188-4  1
2005 Kuczenski R, Segal DS. Stimulant actions in rodents: implications for attention-deficit/hyperactivity disorder treatment and potential substance abuse. Biological Psychiatry. 57: 1391-6. PMID 15950013 DOI: 10.1016/j.biopsych.2004.12.036  1
2005 Swerdlow NR, Kuczenski R, Goins JC, Crain SK, Ma LT, Bongiovanni MJ, Shoemaker JM. Neurochemical analysis of rat strain differences in the startle gating-disruptive effects of dopamine agonists. Pharmacology, Biochemistry, and Behavior. 80: 203-11. PMID 15680173 DOI: 10.1016/j.pbb.2004.11.002  1
2004 Ogden CA, Rich ME, Schork NJ, Paulus MP, Geyer MA, Lohr JB, Kuczenski R, Niculescu AB. Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach. Molecular Psychiatry. 9: 1007-29. PMID 15314610 DOI: 10.1038/sj.mp.4001547  1
2003 Feifel D, Shilling PD, Kuczenski R, Segal DS. Altered extracellular dopamine concentration in the brains of cholecystokinin-A receptor deficient rats. Neuroscience Letters. 348: 147-50. PMID 12932815 DOI: 10.1016/S0304-3940(03)00767-5  1
2003 Segal DS, Kuczenski R, O'Neil ML, Melega WP, Cho AK. Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1730-40. PMID 12865898 DOI: 10.1038/sj.npp.1300247  1
2003 Lohr JB, Kuczenski R, Niculescu AB. Oxidative mechanisms and tardive dyskinesia Cns Drugs. 17: 47-62. PMID 12467492 DOI: 10.2165/00023210-200317010-00004  1
2002 Kuczenski R, Segal DS. Exposure of adolescent rats to oral methylphenidate: preferential effects on extracellular norepinephrine and absence of sensitization and cross-sensitization to methamphetamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7264-71. PMID 12177221  1
2002 Swerdlow NR, Shoemaker JM, Pitcher L, Platten A, Kuczenski R, Eleey CC, Auerbach P. Genetic differences in startle gating-disruptive effects of apomorphine: Evidence for central mediation Behavioral Neuroscience. 116: 682-690. DOI: 10.1037/0735-7044.116.4.682  1
2001 Kuczenski R, Segal DS. Caudate-putamen and nucleus accumbens extracellular acetylcholine responses to methamphetamine binges. Brain Research. 923: 32-8. PMID 11743969 DOI: 10.1016/S0006-8993(01)03193-6  1
2001 Kuczenski R, Segal DS. Locomotor effects of acute and repeated threshold doses of amphetamine and methylphenidate: relative roles of dopamine and norepinephrine. The Journal of Pharmacology and Experimental Therapeutics. 296: 876-83. PMID 11181919  1
2001 Cho AK, Melega WP, Kuczenski R, Segal DS. Relevance of pharmacokinetic parameters in animal models of methamphetamine abuse. Synapse (New York, N.Y.). 39: 161-6. PMID 11180503 DOI: 10.1002/1098-2396(200102)39:2<161::AID-SYN7>3.0.CO;2-E  1
2001 Niculescu AB, Segal DS, Kuczenski R, Barrett T, Hauger RL, Kelsoe JR. Identifying a series of candidate genes for mania and psychosis: A convergent functional genomics approach Physiological Genomics. 2001: 83-91.  1
2000 Niculescu AB, Segal DS, Kuczenski R, Barrett T, Hauger RL, Kelsoe JR. Identifying a series of candidate genes for mania and psychosis: a convergent functional genomics approach. Physiological Genomics. 4: 83-91. PMID 11074017  1
2000 Smith TD, Kuczenski R, George-Friedman K, Malley JD, Foote SL. In vivo microdialysis assessment of extracellular serotonin and dopamine levels in awake monkeys during sustained fluoxetine administration. Synapse (New York, N.Y.). 38: 460-70. PMID 11044893 DOI: 10.1002/1098-2396(20001215)38:4<460::AID-SYN11>3.0.CO;2-D  1
2000 Shilling PD, Kelsoe JR, Kuczenski R, Segal DS. Differential regional zif268 messenger RNA expression in an escalating dose/binge model of amphetamine-induced psychosis. Neuroscience. 96: 83-90. PMID 10683413 DOI: 10.1016/S0306-4522(99)00510-2  1
2000 Niculescu AB, Hauger RL, Segal DS, Kuczenski R, Barrett T, Kelsoe JR. A convergent functional genomics approach identifies GRK3 as a candidate gene for bipolar disordr on 22q American Journal of Medical Genetics - Neuropsychiatric Genetics. 96: 483.  1
2000 Niculescu AB, Segal DS, Kuczenski R, Barrett T, Hauger R, Kelsoe JR. Identifying candidate genes for mania and psychosis using a convergent functional genomics approach American Journal of Medical Genetics - Neuropsychiatric Genetics. 96: 481.  1
1999 Kuczenski R, Segal DS. Dynamic changes in sensitivity occur during the acute response to cocaine and methylphenidate. Psychopharmacology. 147: 96-103. PMID 10591874 DOI: 10.1007/s002130051147  1
1999 Segal DS, Kuczenski R. Escalating dose-binge treatment with methylphenidate: role of serotonin in the emergent behavioral profile. The Journal of Pharmacology and Experimental Therapeutics. 291: 19-30. PMID 10490882  1
1999 Segal DS, Kuczenski R. Escalating dose-binge stimulant exposure: relationship between emergent behavioral profile and differential caudate-putamen and nucleus accumbens dopamine responses. Psychopharmacology. 142: 182-92. PMID 10102771 DOI: 10.1007/s002130050878  1
1999 Kuczenski R, Segal DS. Sensitization of amphetamine-induced stereotyped behaviors during the acute response: role of D1 and D2 dopamine receptors. Brain Research. 822: 164-74. PMID 10082894 DOI: 10.1016/S0006-8993(99)01149-X  1
1999 Cho AK, Melega WP, Kuczenski R, Segal DS, Schmitz DA. Caudate-putamen dopamine and stereotypy response profiles after intravenous and subcutaneous amphetamine. Synapse (New York, N.Y.). 31: 125-33. PMID 10024009 DOI: 10.1002/(SICI)1098-2396(199902)31:2<125::AID-SYN5>3.0.CO;2-W  1
1999 Melega WP, Cho AK, Schmitz D, Kuczenski R, Segal DS. l-methamphetamine pharmacokinetics and pharmacodynamics for assessment of in vivo deprenyl-derived l-methamphetamine. The Journal of Pharmacology and Experimental Therapeutics. 288: 752-8. PMID 9918585  1
1999 Kuczenski R, Segal DS. Sensitization of amphetamine-induced stereotyped behaviors during the acute response. The Journal of Pharmacology and Experimental Therapeutics. 288: 699-709. PMID 9918578  1
1997 Kuczenski R, Segal DS, Todd PK. Behavioral sensitization and extracellular dopamine responses to amphetamine after various treatments. Psychopharmacology. 134: 221-9. PMID 9438672 DOI: 10.1007/s002130050445  1
1997 Segal DS, Kuczenski R. Behavioral alterations induced by an escalating dose-binge pattern of cocaine administration. Behavioural Brain Research. 88: 251-60. PMID 9404634 DOI: 10.1016/S0166-4328(97)00067-3  1
1997 Kuczenski R, Melega WP, Cho AK, Segal DS. Extracellular dopamine and amphetamine after systemic amphetamine administration: comparison to the behavioral response. The Journal of Pharmacology and Experimental Therapeutics. 282: 591-6. PMID 9262319  1
1997 Segal DS, Kuczenski R. Repeated binge exposures to amphetamine and methamphetamine: behavioral and neurochemical characterization. The Journal of Pharmacology and Experimental Therapeutics. 282: 561-73. PMID 9262316  1
1997 Richtand NM, Kelsoe JR, Kuczenski R, Segal DS. Quantification of dopamine D1 and D2 receptor mRNA levels associated with the development of behavioral sensitization in amphetamine treated rats. Neurochemistry International. 31: 131-7. PMID 9185173 DOI: 10.1016/S0197-0186(96)00097-6  1
1997 Kuczenski R, Segal DS. An escalating dose/multiple high-dose binge pattern of amphetamine administration results in differential changes in the extracellular dopamine response profiles in caudate-putamen and nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4441-7. PMID 9151761  1
1997 Kuczenski R, Segal DS. Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: comparison with amphetamine. Journal of Neurochemistry. 68: 2032-7. PMID 9109529  1
1997 Conti LH, Segal DS, Kuczenski R. Maintenance of amphetamine-induced stereotypy and locomotion requires ongoing dopamine receptor activation. Psychopharmacology. 130: 183-8. PMID 9106917 DOI: 10.1007/s002130050227  1
1997 Segal DS, Kuczenski R. An escalating dose "binge" model of amphetamine psychosis: behavioral and neurochemical characteristics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2551-66. PMID 9065515  1
1996 Garcia-Munoz M, Segal DS, Patino P, Young SJ, Kuczenski R, Groves PM. Amphetamine-induced changes in nigrostriatal terminal excitability are modified following repeated amphetamine pretreatment. Brain Research. 720: 131-8. PMID 8782905 DOI: 10.1016/0006-8993(96)00161-8  1
1996 Lacro JP, Kuczenski R, Roznoski M, Warren KA, Harris MJ, Jeste DV. Serum haloperidol levels in older psychotic patients American Journal of Geriatric Psychiatry. 4: 229-236. DOI: 10.1097/00019442-199622430-00006  1
1995 Richtand NM, Kelsoe JR, Segal DS, Kuczenski R. Regional quantification of D1, D2, and D3 dopamine receptor mRNA in rat brain using a ribonuclease protection assay. Brain Research. Molecular Brain Research. 33: 97-103. PMID 8774950 DOI: 10.1016/0169-328X(95)00112-6  1
1995 Richtand NM, Kelsoe JR, Segal DS, Kuczenski R. Regional quantification of dopamine transporter mRNA in rat brain using a ribonuclease protection assay. Neuroscience Letters. 200: 73-6. PMID 8614566 DOI: 10.1016/0304-3940(95)12096-M  1
1995 Kuczenski R, Segal DS, Cho AK, Melega W. Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1308-17. PMID 7869099  1
1995 Segal DS, Kuczenski R, Florin SM. Does dizocilpine (MK-801) selectively block the enhanced responsiveness to repeated amphetamine administration? Behavioral Neuroscience. 109: 532-46. PMID 7662163 DOI: 10.1037/0735-7044.109.3.532  1
1995 Florin SM, Kuczenski R, Segal DS. Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations. The Journal of Pharmacology and Experimental Therapeutics. 274: 231-41. PMID 7616403  1
1994 Florin SM, Kuczenski R, Segal DS. Regional extracellular norepinephrine responses to amphetamine and cocaine and effects of clonidine pretreatment. Brain Research. 654: 53-62. PMID 7982098 DOI: 10.1016/0006-8993(94)91570-9  1
1992 Britton KT, Segal DS, Kuczenski R, Hauger R. Dissociation between in vivo hippocampal norepinephrine response and behavioral/neuroendocrine responses to noise stress in rats. Brain Research. 574: 125-30. PMID 1638389 DOI: 10.1016/0006-8993(92)90808-M  1
1992 Kuczenski R, Segal DS. Regional norepinephrine response to amphetamine using dialysis: comparison with caudate dopamine. Synapse (New York, N.Y.). 11: 164-9. PMID 1626314 DOI: 10.1002/syn.890110210  1
1992 Segal DS, Kuczenski R. Repeated cocaine administration induces behavioral sensitization and corresponding decreased extracellular dopamine responses in caudate and accumbens. Brain Research. 577: 351-5. PMID 1606506 DOI: 10.1016/0006-8993(92)90297-M  1
1992 Manley LD, Kuczenski R, Segal DS, Young SJ, Groves PM. Effects of frequency and pattern of medial forebrain bundle stimulation on caudate dialysate dopamine and serotonin. Journal of Neurochemistry. 58: 1491-8. PMID 1548482  1
1992 Kuczenski R, Segal DS. Differential effects of amphetamine and dopamine uptake blockers (cocaine, nomifensine) on caudate and accumbens dialysate dopamine and 3-methoxytyramine. The Journal of Pharmacology and Experimental Therapeutics. 262: 1085-94. PMID 1527715  1
1992 Florin SM, Kuczenski R, Segal DS. Amphetamine-induced changes in behavior and caudate extracellular acetylcholine. Brain Research. 581: 53-8. PMID 1498671 DOI: 10.1016/0006-8993(92)90343-8  1
1992 Okuda C, Segal DS, Kuczenski R. Deprenyl alters behavior and caudate dopamine through an amphetamine-like action. Pharmacology, Biochemistry, and Behavior. 43: 1075-80. PMID 1475291 DOI: 10.1016/0091-3057(92)90484-W  1
1992 Segal DS, Kuczenski R, Okuda C. Clorgyline-induced increases in presynaptic DA: changes in the behavioral and neurochemical effects of amphetamine using in vivo microdialysis. Pharmacology, Biochemistry, and Behavior. 42: 421-9. PMID 1409775 DOI: 10.1016/0091-3057(92)90135-3  1
1992 Segal DS, Kuczenski R. In vivo microdialysis reveals a diminished amphetamine-induced DA response corresponding to behavioral sensitization produced by repeated amphetamine pretreatment. Brain Research. 571: 330-7. PMID 1377088 DOI: 10.1016/0006-8993(92)90672-V  1
1991 Baker AJ, Zornow MH, Scheller MS, Yaksh TL, Skilling SR, Smullin DH, Larson AA, Kuczenski R. Changes in extracellular concentrations of glutamate, aspartate, glycine, dopamine, serotonin, and dopamine metabolites after transient global ischemia in the rabbit brain. Journal of Neurochemistry. 57: 1370-9. PMID 1895110  1
1991 Kuczenski R, Segal DS, Aizenstein ML. Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2703-12. PMID 1715389  1
1990 Kuczenski R, Segal DS, Manley LD. Apomorphine does not alter amphetamine-induced dopamine release measured in striatal dialysates. Journal of Neurochemistry. 54: 1492-9. PMID 2324735  1
1990 Kuczenski R, Segal DS. In vivo measures of monoamines during amphetamine-induced behaviors in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 14: S37-50. PMID 2097672 DOI: 10.1016/0278-5846(90)90085-U  1
1990 Aizenstein ML, Segal DS, Kuczenski R. Repeated amphetamine and fencamfamine: sensitization and reciprocal cross-sensitization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 3: 283-90. PMID 1976010  1
1990 Lohr JB, Kuczenski R, Bracha HS, Moir M, Jeste DV. Increased indices of free radical activity in the cerebrospinal fluid of patients with tardive dyskinesia Biological Psychiatry. 28: 535-539. PMID 1699612 DOI: 10.1016/0006-3223(90)90490-S  1
1989 Callaway CW, Kuczenski R, Segal DS. Reserpine enhances amphetamine stereotypies without increasing amphetamine-induced changes in striatal dialysate dopamine. Brain Research. 505: 83-90. PMID 2611681 DOI: 10.1016/0006-8993(89)90118-2  1
1989 Kuczenski R, Segal D. Concomitant characterization of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis Journal of Neuroscience. 9: 2051-2065. PMID 2566664  1
1989 Segal DS, Kuczenski R, Swick D. Audiogenic stress response: behavioral characteristics and underlying monoamine mechanisms. Journal of Neural Transmission. 75: 31-50. PMID 2537372 DOI: 10.1007/BF01250642  1
1987 Geyer MA, Russo PV, Segal DS, Kuczenski R. Effects of apomorphine and amphetamine on patterns of locomotor and investigatory behavior in rats. Pharmacology, Biochemistry, and Behavior. 28: 393-9. PMID 3685075 DOI: 10.1016/0091-3057(87)90460-6  1
1987 Segal DS, Kuczenski R. Individual differences in responsiveness to single and repeated amphetamine administration: behavioral characteristics and neurochemical correlates. The Journal of Pharmacology and Experimental Therapeutics. 242: 917-26. PMID 3656119  1
1987 Barnett JV, Segal DS, Kuczenski R. Repeated amphetamine pretreatment alters the responsiveness of striatal dopamine-stimulated adenylate cyclase to amphetamine-induced desensitization. The Journal of Pharmacology and Experimental Therapeutics. 242: 40-7. PMID 2956412  1
1987 Segal DS, Kuczenski R. Behavioral and neurochemical characteristics of stimulant-induced augmentation. Psychopharmacology Bulletin. 23: 417-24. PMID 2893420  1
1987 Atkinson J, Richtand N, Schworer C, Kuczenski R, Soderling T. Phosphorylation of purified rat striatal tyrosine hydroxylase by Ca2+/calmodulin-dependent protein kinase II: effect of an activator protein. Journal of Neurochemistry. 49: 1241-9. PMID 2887635  1
1987 Kuczenski R, Segal DS, Leith NJ, Applegate CD. Effects of amphetamine, methylphenidate, and apomorphine on regional brain serotonin and 5-hydroxyindole acetic acid. Psychopharmacology. 93: 329-35. PMID 2448842 DOI: 10.1007/BF00187252  1
1986 Kuczenski R. Dose response for amphetamine-induced changes in dopamine levels in push-pull perfusates of rat striatum Journal of Neurochemistry. 46: 1605-1611. PMID 3958719  1
1986 Connor CE, Kuczenski R. Evidence that amphetamine and Na+ gradient reversal increase striatal synaptosomal dopamine synthesis through carrier-mediated efflux of dopamine. Biochemical Pharmacology. 35: 3123-30. PMID 3092833 DOI: 10.1016/0006-2952(86)90396-5  1
1986 Barnett JV, Kuczenski R. Desensitization of rat striatal dopamine-stimulated adenylate cyclase after acute amphetamine administration. The Journal of Pharmacology and Experimental Therapeutics. 237: 820-5. PMID 2940359  1
1986 Strait KA, Kuczenski R. Dopamine autoreceptor regulation of the kinetic state of striatal tyrosine hydroxylase Molecular Pharmacology. 29: 561-569. PMID 2872588  1
1985 Richtand NM, Inagami T, Misono K, Kuczenski R. Purification and characterization of rat striatal tyrosine hydroxylase. Comparison of the activation by cyclic AMP-dependent phosphorylation and by other effectors. The Journal of Biological Chemistry. 260: 8465-73. PMID 2861203  1
1985 Richtand N, Schworer C, Kuczenski R, Soderling TR. Phosphorylation of brain tyrosine hydroxylase by calcium, calmodulin-dependent protein kinase Federation Proceedings. 44: No. 1717.  1
1984 Leith NJ, Kuczenski R. Frontal cortex stimulating mimics chronic amphetamine sensitization of the drug-induced locomotor response Federation Proceedings. 43: no. 1682.  1
1984 Richtand NM, Kuczenski R, Inagami T. Mechanisms of activation rat striatal tyrosine hydroxylase Federation Proceedings. 43: no. 3423.  1
1983 Kuczenski R, Leith NJ, Applegate CD. Striatal dopamine metabolism in response to apomorphine: the effects of repeated amphetamine pretreatment. Brain Research. 258: 333-7. PMID 6824917 DOI: 10.1016/0006-8993(83)91161-7  1
1983 Kuczenski R. Effects of phospholipases on the kinetic properties of rat striatal membrane-bound tyrosine hydroxylase. Journal of Neurochemistry. 40: 821-9. PMID 6131107  1
1982 Kuczenski R, Segal DS, Weinberger SB, Browne RG. Evidence that a behavioral augmentation following repeated amphetamine administration does not involve peripheral mechanisms. Pharmacology, Biochemistry, and Behavior. 17: 547-53. PMID 6890688 DOI: 10.1016/0091-3057(82)90317-3  1
1982 Leith NJ, Kuczenski R. Two dissociable components of behavioral sensitization following repeated amphetamine administration. Psychopharmacology. 76: 310-5. PMID 6812103 DOI: 10.1007/BF00449116  1
1982 Creese I, Kuczenski R, Segal D. Lack of behavioral evidence for dopamine autoreceptor subsensitivity after acute electroconvulsive shock. Pharmacology, Biochemistry, and Behavior. 17: 375-6. PMID 6291070 DOI: 10.1016/0091-3057(82)90096-X  1
1981 Kuczenski R, Leith NJ. Chronic amphetamine: is dopamine a link in or a mediator of the development of tolerance and reverse tolerance? Pharmacology, Biochemistry, and Behavior. 15: 405-13. PMID 7291244 DOI: 10.1016/0091-3057(81)90270-7  1
1981 Leith NJ, Kuczenski R. Chronic amphetamine: tolerance and reverse tolerance reflect different behavioral actions of the drug. Pharmacology, Biochemistry, and Behavior. 15: 399-404. PMID 7291243 DOI: 10.1016/0091-3057(81)90269-0  1
1981 Kuczenski R. Monovalent cations and striatal tyrosine hydroxylase. Journal of Neurochemistry. 37: 681-6. PMID 6115890  1
1980 Kuczenski R. Amphetamine-haloperidol interactions on striatal and mesolimbic tyrosine hydroxylase activity and dopamine metabolism Journal of Pharmacology and Experimental Therapeutics. 215: 135-142. PMID 6109012  1
1979 Kuczenski R. Effects of para-chlorophenylalanine on amphetamine and haloperidol-induced changes in striatal dopamine turnover Brain Research. 164: 217-225. PMID 154937 DOI: 10.1016/0006-8993(79)90017-9  1
1978 Kuczenski R. Lack of effect of γ-butyrolactone on amphetamine-induced decrease in striatal synaptosomal dopamine synthesis Journal of Neurochemistry. 31: 347-349. PMID 671029  1
1977 Kuczenski R. Differential effects of reserpine and tetrabenazine on rat striatal synaptosomal dopamine biosynthesis and synaptosomal dopamine pools Journal of Pharmacology and Experimental Therapeutics. 201: 357-367. PMID 870679  1
1977 Kuczenski R. Biphasic effects of amphetamine on striatal dopamine dynamics European Journal of Pharmacology. 46: 249-257. PMID 590334 DOI: 10.1016/0014-2999(77)90340-5  1
1977 Kuczenski R, Schmidt D, Leith N. Amphetamine-haloperidol interactions in rat striatum: Failure to correlate behavioral effects with dopaminergic and cholinergic dynamics Brain Research. 126: 117-129. PMID 558038 DOI: 10.1016/0006-8993(77)90219-0  1
1976 Schmidt D, Kuczenski R. Striatal dopaminergic cholinergic interactions: effect of haloperidol and amphetamine Pharmacologist. 18: No.095.  1
1975 Kuczenski R, Segal DS. Differential effects of D- and L-amphetamine and methylphenidate on rat striatal dopamine biosynthesis. European Journal of Pharmacology. 30: 244-51. PMID 1126362 DOI: 10.1016/0014-2999(75)90106-5  1
1975 Kuczenski R, Segal DS, Mandell AJ. Regional and subcellular distribution and kinetic properties of rat brain choline acetyltransferase--some functional considerations. Journal of Neurochemistry. 24: 39-45. PMID 1110366  1
1975 Kuczenski R. Conformational adaptability of tyrosine hydroxylase in the regulation of striatal dopamine biosynthesis Advances in Biochemical Psychopharmacology. 13: 109-125. PMID 239530  1
1975 Kuczenski R. Effects of catecholamine releasing agents on synaptosomal dopamine biosynthesis: Multiple pools of dopamine or multiple forms of tyrosine hydroxylase? Neuropharmacology. 14: 1-10. PMID 239360 DOI: 10.1016/0028-3908(75)90060-X  1
1974 Kuczenski R, Segal DS. Intrasynaptosomal conversion of tyrosine to dopamine as an index of brain catecholamine biosynthetic capacity. Journal of Neurochemistry. 22: 1039-44. PMID 4852547  1
1974 Kuczenski R. Effect of sodium dodecyl sulfate on the kinetic properties and molecular weight of rat striatal tyrosine hydroxylase Life Sciences. 14: 2379-2384. PMID 4157280 DOI: 10.1016/0024-3205(74)90133-7  1
1974 Squire LR, Kuczenski R, Barondes SH. Tyrosine hydroxylase inhibition by cycloheximide and anisomycin is not responsible for their amnesic effect. Brain Research. 82: 241-8. PMID 4155342 DOI: 10.1016/0006-8993(74)90601-5  1
1974 Mandell AJ, Segal DS, Kuczenski R. Proceedings: Metabolic adaptation to antidepressant drugs--a neurochemical paradox. Psychopharmacology Bulletin. 10: 53-4. PMID 4154475  1
1974 Segal DS, Kuczenski R, Mandell AJ. Theoretical implications of drug-induced adaptive regulation for a biogenic amine hypothesis of affective disorder. Biological Psychiatry. 9: 147-59. PMID 4154114  1
1974 Segal DS, Kuczenski R. Tyrosine hydroxylase activity: regional and subcellular distribution in the brain. Brain Research. 68: 261-6. PMID 4151196 DOI: 10.1016/0006-8993(74)90395-3  1
1973 Kuczenski R. Striatal tyrosine hydroxylases with high and low affinity for tyrosine: Implications for the multiple-pool concept of catecholamines Life Sciences. 13: 247-255. PMID 4148015 DOI: 10.1016/0024-3205(73)90023-4  1
1973 Kuczenski R. Soluble, membrane bound, and detergent solubilized rat striatal tyrosine hydroxylase. pH dependent cofactor binding Journal of Biological Chemistry. 248: 5074-5080. PMID 4146185  1
1973 Kuczenski R. Rat brain tyrosine hydroxylase. Activation by limited tryptic proteolysis Journal of Biological Chemistry. 248: 2261-2265. PMID 4144591  1
1973 Segal DS, Knapp S, Kuczenski RT, Mandell AJ. The effects of environmental isolation on behavior and regional rat brain tyrosine hydroxylase and tryptophan hydroxylase activities. Behavioral Biology. 8: 47-53. PMID 4144216 DOI: 10.1016/S0091-6773(73)80005-7  1
1972 Tobes M, Kuczenski RT, Suelter CH. Yeast pyruvate kinase renaturation after dissociation by guanidine·HCl Archives of Biochemistry and Biophysics. 151: 56-61. PMID 4557977 DOI: 10.1016/0003-9861(72)90472-9  1
1972 Mandell AJ, Knapp S, Kuczenski RT, Segal DS. Methamphetamine-induced alteration in the physical state of rat caudate tyrosine hydroxylase. Biochemical Pharmacology. 21: 2737-50. PMID 4405233 DOI: 10.1016/0006-2952(72)90022-6  1
1972 Segal DS, Kuczenski RT, Mandell AJ. Strain differences in behavior and brain tyrosine hydroxylase activity. Behavioral Biology. 7: 75-81. PMID 4402928 DOI: 10.1016/S0091-6773(72)80190-1  1
1972 Sullivan JL, Segal DS, Kuczenski RT, Mandell AJ. Propranolol-induced rapid activation of rat striatal tyrosine hydroxylase concomitant with behavioral depression. Biological Psychiatry. 4: 193-203. PMID 4402871  1
1972 Kuczenski RT, Mandell AJ. Regulatory properties of soluble and particulate rat brain tyrosine hydroxylase. The Journal of Biological Chemistry. 247: 3114-22. PMID 4402144  1
1972 Kuczenski RT, Mandell AJ. Allosteric activation of hypothalamic tyrosine hydroxylase by ions and sulphated mucopolysaccharides. Journal of Neurochemistry. 19: 131-7. PMID 4257948 DOI: 10.1111/j.1471-4159.1972.tb01262.x  1
1971 Segal DS, Sullivan JL, Kuczenski RT, Mandell AJ. Effects of long-term reserpine treatment on brain tyrosine hydroxylase and behavioral activity. Science (New York, N.Y.). 173: 847-9. PMID 5572177  1
1971 Kuczenski RT, Suelter CH. Fructose 1,6-diphosphate enhanced inactivation of yeast pyruvate kinase at 23°. evidence for a stabilized dimer intermediate Biochemistry. 10: 2867-2872. PMID 5114529  1
1971 Kuczenski RT, Suelter CH. Interactions of fructose 1,6-diphosphate, substrates, and monovalent cations with yeast pyruvate kinase monitored by changes in enzyme fluorescence Biochemistry. 10: 2862-2866. PMID 5114528  1
1970 Kuczenski RT, Suelter CH. Yeast pyruvate kinase. Native and subunit molecular weight Biochemistry. 9: 2043-2047. PMID 5462518  1
1970 Kuczenski RT, Suelter CH. Effect of temperature and effectors on the conformations of yeast pyruvate kinase Biochemistry. 9: 939-945. PMID 5417407  1
1970 Martinez-Carrion M, Kuczenski R, Tiemeier DC, Peterson DL. The structure and enzyme-coenzyme relationship of supernatant aspartate transaminase after dye sensitized photooxidation Journal of Biological Chemistry. 245: 799-805. PMID 4984627  1
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