Ron Kuczenski - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Drugs of addiction

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Le Cozannet R, Markou A, Kuczenski R. Extended-access, but not limited-access, methamphetamine self-administration induces behavioral and nucleus accumbens dopamine response changes in rats. The European Journal of Neuroscience. 38: 3487-95. PMID 24112125 DOI: 10.1111/Ejn.12361  0.339
2013 Laćan G, Hadamitzky M, Kuczenski R, Melega WP. Alterations in the striatal dopamine system during intravenous methamphetamine exposure: Effects of contingent and noncontingent administration Synapse. 67: 476-488. PMID 23417852 DOI: 10.1002/Syn.21654  0.341
2012 Hadamitzky M, McCunney S, Markou A, Kuczenski R. Development of stereotyped behaviors during prolonged escalation of methamphetamine self-administration in rats. Psychopharmacology. 223: 259-69. PMID 22526541 DOI: 10.1007/S00213-012-2713-1  0.357
2010 Kuczenski R. Amphetamines Encyclopedia of Neuroscience. 319-323. DOI: 10.1016/B978-008045046-9.01142-6  0.334
2009 Kuczenski R, Segal DS, Melega WP, Lacan G, McCunney SJ. Human methamphetamine pharmacokinetics simulated in the rat: behavioral and neurochemical effects of a 72-h binge. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2430-41. PMID 19571794 DOI: 10.1038/Npp.2009.73  0.374
2006 O'Neil ML, Kuczenski R, Segal DS, Cho AK, Lacan G, Melega WP. Escalating dose pretreatment induces pharmacodynamic and not pharmacokinetic tolerance to a subsequent high-dose methamphetamine binge. Synapse (New York, N.Y.). 60: 465-73. PMID 16897726 DOI: 10.1002/Syn.20320  0.368
2006 Swerdlow NR, Shoemaker JM, Kuczenski R, Bongiovanni MJ, Neary AC, Tochen LS, Saint Marie RL. Forebrain D1 function and sensorimotor gating in rats: effects of D1 blockade, frontal lesions and dopamine denervation. Neuroscience Letters. 402: 40-5. PMID 16644125 DOI: 10.1016/J.Neulet.2006.03.060  0.312
2006 Segal DS, Kuczenski R. Human methamphetamine pharmacokinetics simulated in the rat: single daily intravenous administration reveals elements of sensitization and tolerance. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 941-55. PMID 16123749 DOI: 10.1038/Sj.Npp.1300865  0.385
2005 Segal DS, Kuczenski R, O'Neil ML, Melega WP, Cho AK. Prolonged exposure of rats to intravenous methamphetamine: behavioral and neurochemical characterization. Psychopharmacology. 180: 501-12. PMID 15959831 DOI: 10.1007/S00213-005-2188-4  0.407
2005 Swerdlow NR, Kuczenski R, Goins JC, Crain SK, Ma LT, Bongiovanni MJ, Shoemaker JM. Neurochemical analysis of rat strain differences in the startle gating-disruptive effects of dopamine agonists. Pharmacology, Biochemistry, and Behavior. 80: 203-11. PMID 15680173 DOI: 10.1016/J.Pbb.2004.11.002  0.343
2003 Feifel D, Shilling PD, Kuczenski R, Segal DS. Altered extracellular dopamine concentration in the brains of cholecystokinin-A receptor deficient rats. Neuroscience Letters. 348: 147-50. PMID 12932815 DOI: 10.1016/S0304-3940(03)00767-5  0.382
2003 Segal DS, Kuczenski R, O'Neil ML, Melega WP, Cho AK. Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1730-40. PMID 12865898 DOI: 10.1038/Sj.Npp.1300247  0.334
2002 Kuczenski R, Segal DS. Exposure of adolescent rats to oral methylphenidate: preferential effects on extracellular norepinephrine and absence of sensitization and cross-sensitization to methamphetamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7264-71. PMID 12177221 DOI: 10.1523/Jneurosci.22-16-07264.2002  0.352
2002 Swerdlow NR, Shoemaker JM, Pitcher L, Platten A, Kuczenski R, Eleey CC, Auerbach P. Genetic differences in startle gating-disruptive effects of apomorphine: evidence for central mediation. Behavioral Neuroscience. 116: 682-90. PMID 12148935 DOI: 10.1037//0735-7044.116.4.682  0.311
2001 Kuczenski R, Segal DS. Caudate-putamen and nucleus accumbens extracellular acetylcholine responses to methamphetamine binges. Brain Research. 923: 32-8. PMID 11743969 DOI: 10.1016/S0006-8993(01)03193-6  0.46
2001 Kuczenski R, Segal DS. Locomotor effects of acute and repeated threshold doses of amphetamine and methylphenidate: relative roles of dopamine and norepinephrine. The Journal of Pharmacology and Experimental Therapeutics. 296: 876-83. PMID 11181919  0.44
2000 Shilling PD, Kelsoe JR, Kuczenski R, Segal DS. Differential regional zif268 messenger RNA expression in an escalating dose/binge model of amphetamine-induced psychosis. Neuroscience. 96: 83-90. PMID 10683413 DOI: 10.1016/S0306-4522(99)00510-2  0.311
1999 Kuczenski R, Segal DS. Dynamic changes in sensitivity occur during the acute response to cocaine and methylphenidate. Psychopharmacology. 147: 96-103. PMID 10591874 DOI: 10.1007/S002130051147  0.469
1999 Segal DS, Kuczenski R. Escalating dose-binge treatment with methylphenidate: role of serotonin in the emergent behavioral profile. The Journal of Pharmacology and Experimental Therapeutics. 291: 19-30. PMID 10490882  0.512
1999 Segal DS, Kuczenski R. Escalating dose-binge stimulant exposure: relationship between emergent behavioral profile and differential caudate-putamen and nucleus accumbens dopamine responses. Psychopharmacology. 142: 182-92. PMID 10102771 DOI: 10.1007/S002130050878  0.465
1999 Kuczenski R, Segal DS. Sensitization of amphetamine-induced stereotyped behaviors during the acute response: role of D1 and D2 dopamine receptors. Brain Research. 822: 164-74. PMID 10082894 DOI: 10.1016/S0006-8993(99)01149-X  0.421
1999 Cho AK, Melega WP, Kuczenski R, Segal DS, Schmitz DA. Caudate-putamen dopamine and stereotypy response profiles after intravenous and subcutaneous amphetamine. Synapse (New York, N.Y.). 31: 125-33. PMID 10024009 DOI: 10.1002/(Sici)1098-2396(199902)31:2<125::Aid-Syn5>3.0.Co;2-W  0.459
1999 Kuczenski R, Segal DS. Sensitization of amphetamine-induced stereotyped behaviors during the acute response. The Journal of Pharmacology and Experimental Therapeutics. 288: 699-709. PMID 9918578  0.505
1997 Kuczenski R, Segal DS, Todd PK. Behavioral sensitization and extracellular dopamine responses to amphetamine after various treatments. Psychopharmacology. 134: 221-9. PMID 9438672 DOI: 10.1007/S002130050445  0.439
1997 Segal DS, Kuczenski R. Behavioral alterations induced by an escalating dose-binge pattern of cocaine administration. Behavioural Brain Research. 88: 251-60. PMID 9404634 DOI: 10.1016/S0166-4328(97)00067-3  0.367
1997 Kuczenski R, Melega WP, Cho AK, Segal DS. Extracellular dopamine and amphetamine after systemic amphetamine administration: comparison to the behavioral response. The Journal of Pharmacology and Experimental Therapeutics. 282: 591-6. PMID 9262319  0.463
1997 Segal DS, Kuczenski R. Repeated binge exposures to amphetamine and methamphetamine: behavioral and neurochemical characterization. The Journal of Pharmacology and Experimental Therapeutics. 282: 561-73. PMID 9262316  0.445
1997 Richtand NM, Kelsoe JR, Kuczenski R, Segal DS. Quantification of dopamine D1 and D2 receptor mRNA levels associated with the development of behavioral sensitization in amphetamine treated rats. Neurochemistry International. 31: 131-7. PMID 9185173 DOI: 10.1016/S0197-0186(96)00097-6  0.319
1997 Kuczenski R, Segal DS. An escalating dose/multiple high-dose binge pattern of amphetamine administration results in differential changes in the extracellular dopamine response profiles in caudate-putamen and nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4441-7. PMID 9151761 DOI: 10.1523/Jneurosci.17-11-04441.1997  0.483
1997 Kuczenski R, Segal DS. Effects of methylphenidate on extracellular dopamine, serotonin, and norepinephrine: comparison with amphetamine. Journal of Neurochemistry. 68: 2032-7. PMID 9109529 DOI: 10.1046/J.1471-4159.1997.68052032.X  0.499
1997 Conti LH, Segal DS, Kuczenski R. Maintenance of amphetamine-induced stereotypy and locomotion requires ongoing dopamine receptor activation. Psychopharmacology. 130: 183-8. PMID 9106917 DOI: 10.1007/S002130050227  0.481
1997 Segal DS, Kuczenski R. An escalating dose "binge" model of amphetamine psychosis: behavioral and neurochemical characteristics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2551-66. PMID 9065515 DOI: 10.1523/Jneurosci.17-07-02551.1997  0.428
1996 Garcia-Munoz M, Segal DS, Patino P, Young SJ, Kuczenski R, Groves PM. Amphetamine-induced changes in nigrostriatal terminal excitability are modified following repeated amphetamine pretreatment. Brain Research. 720: 131-8. PMID 8782905 DOI: 10.1016/0006-8993(96)00161-8  0.381
1996 Kuczenski R, Segal D. Behavioral neurotransmitter responses to a “binge” pattern of amphetamine administration European Neuropsychopharmacology. 6: 155. DOI: 10.1016/0924-977X(96)88022-9  0.392
1995 Kuczenski R, Segal DS, Cho AK, Melega W. Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1308-17. PMID 7869099 DOI: 10.1523/Jneurosci.15-02-01308.1995  0.465
1995 Segal DS, Kuczenski R, Florin SM. Does dizocilpine (MK-801) selectively block the enhanced responsiveness to repeated amphetamine administration? Behavioral Neuroscience. 109: 532-46. PMID 7662163 DOI: 10.1037//0735-7044.109.3.532  0.397
1995 Florin SM, Kuczenski R, Segal DS. Effects of reserpine on extracellular caudate dopamine and hippocampus norepinephrine responses to amphetamine and cocaine: mechanistic and behavioral considerations. The Journal of Pharmacology and Experimental Therapeutics. 274: 231-41. PMID 7616403 DOI: 10.1038/Sj.Npp.1380146  0.471
1994 Florin SM, Kuczenski R, Segal DS. Regional extracellular norepinephrine responses to amphetamine and cocaine and effects of clonidine pretreatment. Brain Research. 654: 53-62. PMID 7982098 DOI: 10.1016/0006-8993(94)91570-9  0.397
1992 Kuczenski R, Segal DS. Regional norepinephrine response to amphetamine using dialysis: comparison with caudate dopamine. Synapse (New York, N.Y.). 11: 164-9. PMID 1626314 DOI: 10.1002/Syn.890110210  0.465
1992 Segal DS, Kuczenski R. Repeated cocaine administration induces behavioral sensitization and corresponding decreased extracellular dopamine responses in caudate and accumbens. Brain Research. 577: 351-5. PMID 1606506 DOI: 10.1016/0006-8993(92)90297-M  0.455
1992 Manley LD, Kuczenski R, Segal DS, Young SJ, Groves PM. Effects of frequency and pattern of medial forebrain bundle stimulation on caudate dialysate dopamine and serotonin. Journal of Neurochemistry. 58: 1491-8. PMID 1548482 DOI: 10.1111/J.1471-4159.1992.Tb11369.X  0.365
1992 Kuczenski R, Segal DS. Differential effects of amphetamine and dopamine uptake blockers (cocaine, nomifensine) on caudate and accumbens dialysate dopamine and 3-methoxytyramine. The Journal of Pharmacology and Experimental Therapeutics. 262: 1085-94. PMID 1527715  0.406
1992 Florin SM, Kuczenski R, Segal DS. Amphetamine-induced changes in behavior and caudate extracellular acetylcholine. Brain Research. 581: 53-8. PMID 1498671 DOI: 10.1016/0006-8993(92)90343-8  0.468
1992 Okuda C, Segal DS, Kuczenski R. Deprenyl alters behavior and caudate dopamine through an amphetamine-like action. Pharmacology, Biochemistry, and Behavior. 43: 1075-80. PMID 1475291 DOI: 10.1016/0091-3057(92)90484-W  0.468
1992 Segal DS, Kuczenski R, Okuda C. Clorgyline-induced increases in presynaptic DA: changes in the behavioral and neurochemical effects of amphetamine using in vivo microdialysis. Pharmacology, Biochemistry, and Behavior. 42: 421-9. PMID 1409775 DOI: 10.1016/0091-3057(92)90135-3  0.51
1992 Segal DS, Kuczenski R. In vivo microdialysis reveals a diminished amphetamine-induced DA response corresponding to behavioral sensitization produced by repeated amphetamine pretreatment. Brain Research. 571: 330-7. PMID 1377088 DOI: 10.1016/0006-8993(92)90672-V  0.513
1991 Kuczenski R, Segal DS, Aizenstein ML. Amphetamine, cocaine, and fencamfamine: relationship between locomotor and stereotypy response profiles and caudate and accumbens dopamine dynamics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2703-12. PMID 1715389 DOI: 10.1523/Jneurosci.11-09-02703.1991  0.499
1990 Kuczenski R, Segal DS, Manley LD. Apomorphine does not alter amphetamine-induced dopamine release measured in striatal dialysates. Journal of Neurochemistry. 54: 1492-9. PMID 2324735 DOI: 10.1111/J.1471-4159.1990.Tb01196.X  0.421
1990 Kuczenski R, Segal DS. In vivo measures of monoamines during amphetamine-induced behaviors in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 14: S37-50. PMID 2097672 DOI: 10.1016/0278-5846(90)90085-U  0.508
1990 Aizenstein ML, Segal DS, Kuczenski R. Repeated amphetamine and fencamfamine: sensitization and reciprocal cross-sensitization. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 3: 283-90. PMID 1976010  0.455
1989 Callaway CW, Kuczenski R, Segal DS. Reserpine enhances amphetamine stereotypies without increasing amphetamine-induced changes in striatal dialysate dopamine. Brain Research. 505: 83-90. PMID 2611681 DOI: 10.1016/0006-8993(89)90118-2  0.427
1989 Kuczenski R, Segal D. Concomitant characterization of behavioral and striatal neurotransmitter response to amphetamine using in vivo microdialysis Journal of Neuroscience. 9: 2051-2065. PMID 2566664 DOI: 10.1523/Jneurosci.09-06-02051.1989  0.443
1989 Callaway CW, Segal DS, Kuczenski RT. Amphetamine-induced behavior and dopamine release following reserpine Biological Psychiatry. 25: A47-A48. DOI: 10.1016/0006-3223(89)91582-5  0.43
1987 Geyer MA, Russo PV, Segal DS, Kuczenski R. Effects of apomorphine and amphetamine on patterns of locomotor and investigatory behavior in rats. Pharmacology, Biochemistry, and Behavior. 28: 393-9. PMID 3685075 DOI: 10.1016/0091-3057(87)90460-6  0.467
1987 Segal DS, Kuczenski R. Individual differences in responsiveness to single and repeated amphetamine administration: behavioral characteristics and neurochemical correlates. The Journal of Pharmacology and Experimental Therapeutics. 242: 917-26. PMID 3656119  0.441
1987 Barnett JV, Segal DS, Kuczenski R. Repeated amphetamine pretreatment alters the responsiveness of striatal dopamine-stimulated adenylate cyclase to amphetamine-induced desensitization. The Journal of Pharmacology and Experimental Therapeutics. 242: 40-7. PMID 2956412  0.464
1987 Kuczenski R, Segal DS, Leith NJ, Applegate CD. Effects of amphetamine, methylphenidate, and apomorphine on regional brain serotonin and 5-hydroxyindole acetic acid. Psychopharmacology. 93: 329-35. PMID 2448842 DOI: 10.1007/Bf00187252  0.386
1986 Kuczenski R. Dose response for amphetamine-induced changes in dopamine levels in push-pull perfusates of rat striatum Journal of Neurochemistry. 46: 1605-1611. PMID 3958719  0.412
1986 Connor CE, Kuczenski R. Evidence that amphetamine and Na+ gradient reversal increase striatal synaptosomal dopamine synthesis through carrier-mediated efflux of dopamine. Biochemical Pharmacology. 35: 3123-30. PMID 3092833 DOI: 10.1016/0006-2952(86)90396-5  0.31
1986 Barnett JV, Kuczenski R. Desensitization of rat striatal dopamine-stimulated adenylate cyclase after acute amphetamine administration. The Journal of Pharmacology and Experimental Therapeutics. 237: 820-5. PMID 2940359  0.385
1986 Strait KA, Kuczenski R. Dopamine autoreceptor regulation of the kinetic state of striatal tyrosine hydroxylase Molecular Pharmacology. 29: 561-569. PMID 2872588  0.324
1983 Kuczenski R, Leith NJ, Applegate CD. Striatal dopamine metabolism in response to apomorphine: the effects of repeated amphetamine pretreatment. Brain Research. 258: 333-7. PMID 6824917 DOI: 10.1016/0006-8993(83)91161-7  0.43
1982 Kuczenski R, Segal DS, Weinberger SB, Browne RG. Evidence that a behavioral augmentation following repeated amphetamine administration does not involve peripheral mechanisms. Pharmacology, Biochemistry, and Behavior. 17: 547-53. PMID 6890688 DOI: 10.1016/0091-3057(82)90317-3  0.405
1982 Leith NJ, Kuczenski R. Two dissociable components of behavioral sensitization following repeated amphetamine administration. Psychopharmacology. 76: 310-5. PMID 6812103 DOI: 10.1007/BF00449116  0.367
1982 Creese I, Kuczenski R, Segal D. Lack of behavioral evidence for dopamine autoreceptor subsensitivity after acute electroconvulsive shock. Pharmacology, Biochemistry, and Behavior. 17: 375-6. PMID 6291070 DOI: 10.1016/0091-3057(82)90096-X  0.476
1981 Kuczenski R, Leith NJ. Chronic amphetamine: is dopamine a link in or a mediator of the development of tolerance and reverse tolerance? Pharmacology, Biochemistry, and Behavior. 15: 405-13. PMID 7291244 DOI: 10.1016/0091-3057(81)90270-7  0.447
1980 Kuczenski R. Amphetamine-haloperidol interactions on striatal and mesolimbic tyrosine hydroxylase activity and dopamine metabolism Journal of Pharmacology and Experimental Therapeutics. 215: 135-142. PMID 6109012  0.379
1979 Kuczenski R. Effects of para-chlorophenylalanine on amphetamine and haloperidol-induced changes in striatal dopamine turnover Brain Research. 164: 217-225. PMID 154937 DOI: 10.1016/0006-8993(79)90017-9  0.418
1978 Kuczenski R. Lack of effect of γ-butyrolactone on amphetamine-induced decrease in striatal synaptosomal dopamine synthesis Journal of Neurochemistry. 31: 347-349. PMID 671029  0.366
1977 Kuczenski R. Differential effects of reserpine and tetrabenazine on rat striatal synaptosomal dopamine biosynthesis and synaptosomal dopamine pools Journal of Pharmacology and Experimental Therapeutics. 201: 357-367. PMID 870679  0.38
1977 Kuczenski R. Biphasic effects of amphetamine on striatal dopamine dynamics European Journal of Pharmacology. 46: 249-257. PMID 590334 DOI: 10.1016/0014-2999(77)90340-5  0.381
1977 Kuczenski R, Schmidt D, Leith N. Amphetamine-haloperidol interactions in rat striatum: Failure to correlate behavioral effects with dopaminergic and cholinergic dynamics Brain Research. 126: 117-129. PMID 558038 DOI: 10.1016/0006-8993(77)90219-0  0.431
1976 Schmidt D, Kuczenski R. Striatal dopaminergic cholinergic interactions: effect of haloperidol and amphetamine Pharmacologist. 18: No.095.  0.303
1975 Kuczenski R, Segal DS. Differential effects of D- and L-amphetamine and methylphenidate on rat striatal dopamine biosynthesis. European Journal of Pharmacology. 30: 244-51. PMID 1126362 DOI: 10.1016/0014-2999(75)90106-5  0.398
1975 Kuczenski R. Conformational adaptability of tyrosine hydroxylase in the regulation of striatal dopamine biosynthesis Advances in Biochemical Psychopharmacology. 13: 109-125. PMID 239530  0.326
1975 Kuczenski R. Effects of catecholamine releasing agents on synaptosomal dopamine biosynthesis: Multiple pools of dopamine or multiple forms of tyrosine hydroxylase? Neuropharmacology. 14: 1-10. PMID 239360 DOI: 10.1016/0028-3908(75)90060-X  0.369
1972 Mandell AJ, Knapp S, Kuczenski RT, Segal DS. Methamphetamine-induced alteration in the physical state of rat caudate tyrosine hydroxylase. Biochemical Pharmacology. 21: 2737-50. PMID 4405233 DOI: 10.1016/0006-2952(72)90022-6  0.317
1971 Segal DS, Sullivan JL, Kuczenski RT, Mandell AJ. Effects of long-term reserpine treatment on brain tyrosine hydroxylase and behavioral activity. Science (New York, N.Y.). 173: 847-9. PMID 5572177 DOI: 10.1126/Science.173.3999.847  0.313
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