Takato Hiranita - Publications

Affiliations: 
National Center for Toxicological Research, FDA 
Area:
Drug Abuse, cocaine, methamphetamine, ketamine, heroin, nicotine, self-administration, microdialysis
Website:
https://www.researchgate.net/profile/Takato_Hiranita

49/91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hersey M, Mereu M, Jones CS, Bartole MK, Chen AY, Cao J, Hiranita T, Chun LE, Lopez JP, Katz JL, Newman AH, Tanda G. Dual DAT and sigma receptor inhibitors attenuate cocaine effects on nucleus accumbens dopamine dynamics in rats. The European Journal of Neuroscience. PMID 38444104 DOI: 10.1111/ejn.16293  0.712
2023 Fitzgerald LR, Gannon BM, Walther D, Landavazo A, Hiranita T, Blough BE, Baumann MH, Fantegrossi WE. Structure-activity relationships for locomotor stimulant effects and monoamine transporter interactions of substituted amphetamines and cathinones. Neuropharmacology. 245: 109827. PMID 38154512 DOI: 10.1016/j.neuropharm.2023.109827  0.372
2022 Obeng S, León F, Patel A, Zuarth Gonzalez JD, Da Silva LC, Restrepo LF, Gamez-Jimenez LR, Ho NP, Guerrero Calvache MP, Pallares VL, Helmes JA, Shiomitsu SK, Soto PL, McCurdy CR, McMahon LR, ... ... Hiranita T, et al. Interactive Effects of µ-Opioid and Adrenergic-α Receptor Agonists in Rats: Pharmacological Investigation of the Primary Kratom Alkaloid Mitragynine and Its Metabolite 7-Hydroxymitragynine. The Journal of Pharmacology and Experimental Therapeutics. PMID 36153006 DOI: 10.1124/jpet.122.001192  0.317
2022 Hiranita T, Zuarth Gonzalez J, Patel RC, Mazpule-Carrigan CC, Martins Rocha J, Gamez Jimenez LR, Ho NP, Patel A, Obeng S, Leon F, Mottinelli M, Mukhopadhyay S, McCurdy CR, McMahon LR. Effects of Mitragynine and its Active Metabolites on the Reinforcing Effects of Remifentanil and Cocaine in Rats Self-Administering Remifentanil. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 35552940 DOI: 10.1096/fasebj.2022.36.S1.R5776  0.47
2020 Soto PL, Hiranita T. Effects of benztropine analogs on delay discounting in rats. Psychopharmacology. PMID 32964243 DOI: 10.1007/s00213-020-05655-0  0.347
2020 Behnood-Rod A, Chellian R, Wilson R, Hiranita T, Sharma A, Leon F, McCurdy CR, McMahon LR, Bruijnzeel AW. Evaluation of the rewarding effects of mitragynine and 7-hydroxymitragynine in an intracranial self-stimulation procedure in male and female rats. Drug and Alcohol Dependence. 215: 108235. PMID 32889450 DOI: 10.1016/J.Drugalcdep.2020.108235  0.301
2020 Mereu M, Hiranita T, Jordan CJ, Chun LE, Lopez JP, Coggiano MA, Quarterman JC, Bi GH, Keighron JD, Xi ZX, Newman AH, Katz JL, Tanda G. Modafinil potentiates cocaine self-administration by a dopamine-independent mechanism: possible involvement of gap junctions. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32340023 DOI: 10.1038/S41386-020-0680-5  0.72
2020 Tanda G, Mereu M, Hiranita T, Jordan CJ, Chun LE, Lopez JP, Coggiano MA, Quarterman JC, Bi G, Keighron JD, Xi Z, Katz JL, Newman AH. Gap Junctions Modulate The Effects Of Modafinil On Cocaine Self‐Administration Behavior In A Dopamine‐Independent Fashion In Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04150  0.649
2018 Hong WC, Wasko MJ, Wilkinson DS, Hiranita T, Li L, Hayashi S, Snell DB, Madura JD, Surratt CK, Katz JL. Dopamine Transporter Dynamics of N-Substituted Benztropine Analogs with Atypical Behavioral Effects. The Journal of Pharmacology and Experimental Therapeutics. PMID 29945932 DOI: 10.1124/Jpet.118.250498  0.737
2017 Hong WC, Yano H, Hiranita T, Chin FT, McCurdy CR, Su TP, Amara SG, Katz JL. The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats. The Journal of Biological Chemistry. PMID 28495886 DOI: 10.1074/Jbc.M116.774075  0.749
2017 Hiranita T, Hong WC, Kopajtic T, Katz JL. Sigma Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self Administration. The Journal of Pharmacology and Experimental Therapeutics. PMID 28442581 DOI: 10.1124/Jpet.117.241109  0.759
2017 Katz JL, Hiranita T, Hong WC, Job MO, McCurdy CR. A Role for Sigma Receptors in Stimulant Self-Administration and Addiction. Handbook of Experimental Pharmacology. PMID 28110353 DOI: 10.1007/164_2016_94  0.759
2016 Hiranita T. Lack of Effects of Toll-Like Receptor 4 Antagonists on the Reinforcing Effects of Cocaine and Remifentanil. Journal of Alcoholism and Drug Dependence. 4. PMID 28070538 DOI: 10.4172/2329-6488  0.555
2016 Hiranita T. DAT Conformation Does Not Predict the Ability of Atypical Dopamine Uptake Inhibitors to Substitute for Cocaine. Journal of Alcoholism and Drug Dependence. 4. PMID 27588299  0.499
2016 Tanda G, Mereu M, Hiranita T, Quarterman J, Coggiano M, Katz JL. Lack of Specific Involvement of (+)-Naloxone and (+)-Naltrexone on the Reinforcing and Neurochemical Effects of Cocaine and Opioids. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27296151 DOI: 10.1038/Npp.2016.91  0.736
2016 Katz JL, Hiranita T, Kopajtic TA, Rice KC, Mesangeau C, Narayanan S, Abdelazeem AH, McCurdy CR. Blockade of Cocaine or Sigma Receptor Agonist Self-Administration by Subtype- Selective Sigma Receptor Antagonists. The Journal of Pharmacology and Experimental Therapeutics. PMID 27189970 DOI: 10.1124/Jpet.116.232728  0.722
2016 Freyberg Z, Sonders MS, Aguilar JI, Hiranita T, Karam CS, Flores J, Pizzo AB, Zhang Y, Farino ZJ, Chen A, Martin CA, Kopajtic TA, Fei H, Hu G, Lin YY, et al. Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain. Nature Communications. 7: 10652. PMID 26879809 DOI: 10.1038/Ncomms10652  0.637
2015 Hiranita T. Cocaine Antagonists; Studies on Cocaine Self-Administration. Journal of Alcoholism and Drug Dependence. 3. PMID 27398394 DOI: 10.4172/2329-6488.1000e125  0.569
2015 Hiranita T. Preclinical Efficacy of Novel Vesicular Monoamine Transporter 2 Inhibitors as Antagonists of d-Methamphetamine Self-Administration in Rats. Journal of Alcoholism and Drug Dependence. 3. PMID 27398393 DOI: 10.4172/2329-6488.1000e127  0.315
2015 Hiranita T, Collins GT. Differential Roles for Dopamine D1-Like and D2-Like Receptors in Mediating the Reinforcing Effects of Cocaine: Convergent Evidence from Pharmacological and Genetic Studies. Journal of Alcoholism and Drug Dependence. 3. PMID 27390753 DOI: 10.4172/2329-6488.1000E124  0.314
2015 Katz JL, Hong WC, Hiranita T, Su TP. A role for sigma receptors in stimulant self-administration and addiction. Behavioural Pharmacology. PMID 26650253 DOI: 10.1097/Fbp.0000000000000209  0.7
2015 Soto PL, Hiranita T, Xu M, Hursh SR, Grandy DK, Katz JL. Dopamine D2-Like Receptors and Behavioral Economics of Food Reinforcement. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26205210 DOI: 10.1038/Npp.2015.223  0.459
2015 Northcutt AL, Hutchinson MR, Wang X, Baratta MV, Hiranita T, Cochran TA, Pomrenze MB, Galer EL, Kopajtic TA, Li CM, Amat J, Larson G, Cooper DC, Huang Y, O'Neill CE, et al. DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling. Molecular Psychiatry. PMID 25644383 DOI: 10.1038/Mp.2014.177  0.725
2015 Tanda G, Mereu M, Hiranita T, Newman AH, Katz J. (±)-Modafinil potentiates cocaine self-administration but not the effects on DA levels in rodents Drug and Alcohol Dependence. 146: e116. DOI: 10.1016/J.Drugalcdep.2014.09.682  0.68
2014 Kohut SJ, Hiranita T, Hong SK, Ebbs AL, Tronci V, Green J, Garcés-Ramírez L, Chun LE, Mereu M, Newman AH, Katz JL, Tanda G. Preference for distinct functional conformations of the dopamine transporter alters the relationship between subjective effects of cocaine and stimulation of mesolimbic dopamine. Biological Psychiatry. 76: 802-9. PMID 24853388 DOI: 10.1016/J.Biopsych.2014.03.031  0.697
2014 Soto PL, Hiranita T, Grandy DK, Katz JL. Choice for response alternatives differing in reinforcement frequency in dopamine D2 receptor mutant and Swiss-Webster mice. Psychopharmacology. 231: 3169-77. PMID 24682471 DOI: 10.1007/S00213-014-3495-4  0.582
2014 Hiranita T, Wilkinson DS, Hong WC, Zou MF, Kopajtic TA, Soto PL, Lupica CR, Newman AH, Katz JL. 2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter. The Journal of Pharmacology and Experimental Therapeutics. 349: 297-309. PMID 24518035 DOI: 10.1124/Jpet.113.212738  0.783
2014 Hiranita T, Kohut SJ, Soto PL, Tanda G, Kopajtic TA, Katz JL. Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats. The Journal of Pharmacology and Experimental Therapeutics. 348: 174-91. PMID 24194527 DOI: 10.1124/Jpet.113.208264  0.725
2013 Hiranita T, Soto PL, Tanda G, Kopajtic TA, Katz JL. Stimulants as specific inducers of dopamine-independent σ agonist self-administration in rats. The Journal of Pharmacology and Experimental Therapeutics. 347: 20-9. PMID 23908387 DOI: 10.1124/Jpet.113.207522  0.725
2013 Hiranita T, Mereu M, Soto PL, Tanda G, Katz JL. Self-administration of cocaine induces dopamine-independent self-administration of sigma agonists. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 605-15. PMID 23187725 DOI: 10.1038/Npp.2012.224  0.749
2013 Li L, Hiranita T, Hayashi S, Newman AH, Katz JL. The stereotypy-inducing effects of N-substituted benztropine analogs alone and in combination with cocaine do not account for their blockade of cocaine self-administration. Psychopharmacology. 225: 733-42. PMID 22975727 DOI: 10.1007/S00213-012-2862-2  0.74
2012 Hutchinson MR, Northcutt AL, Hiranita T, Wang X, Lewis SS, Thomas J, van Steeg K, Kopajtic TA, Loram LC, Sfregola C, Galer E, Miles NE, Bland ST, Amat J, Rozeske RR, et al. Opioid activation of toll-like receptor 4 contributes to drug reinforcement. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11187-200. PMID 22895704 DOI: 10.1523/Jneurosci.0684-12.2012  0.559
2011 Katz JL, Su TP, Hiranita T, Hayashi T, Tanda G, Kopajtic T, Tsai SY. A Role for Sigma Receptors in Stimulant Self Administration and Addiction. Pharmaceuticals (Basel, Switzerland). 4: 880-914. PMID 21904468 DOI: 10.3390/Ph4060880  0.728
2011 Hiranita T, Soto PL, Kohut SJ, Kopajtic T, Cao J, Newman AH, Tanda G, Katz JL. Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors. The Journal of Pharmacology and Experimental Therapeutics. 339: 662-77. PMID 21859929 DOI: 10.1124/Jpet.111.185025  0.737
2011 Hiranita T, Soto PL, Tanda G, Katz JL. Lack of cocaine-like discriminative-stimulus effects of σ-receptor agonists in rats. Behavioural Pharmacology. 22: 525-30. PMID 21808192 DOI: 10.1097/Fbp.0B013E328349Ab22  0.733
2011 Garcés-Ramírez L, Green JL, Hiranita T, Kopajtic TA, Mereu M, Thomas AM, Mesangeau C, Narayanan S, McCurdy CR, Katz JL, Tanda G. Sigma receptor agonists: receptor binding and effects on mesolimbic dopamine neurotransmission assessed by microdialysis. Biological Psychiatry. 69: 208-17. PMID 20950794 DOI: 10.1016/J.Biopsych.2010.07.026  0.705
2010 Hiranita T, Soto PL, Tanda G, Katz JL. Reinforcing effects of sigma-receptor agonists in rats trained to self-administer cocaine. The Journal of Pharmacology and Experimental Therapeutics. 332: 515-24. PMID 19892920 DOI: 10.1124/Jpet.109.159236  0.747
2010 Hiranita T, Yamamoto T, Nawata Y. A tryptamine-derived catecholaminergic enhancer, (-)-1-(benzofuran-2-yl)-2-propylaminopentane [(-)-BPAP], attenuates reinstatement of methamphetamine-seeking behavior in rats. Neuroscience. 165: 300-12. PMID 19883738 DOI: 10.1016/J.Neuroscience.2009.10.055  0.577
2010 Nawata Y, Hiranita T, Yamamoto T. A cannabinoid CB(1) receptor antagonist ameliorates impairment of recognition memory on withdrawal from MDMA (Ecstasy). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 515-20. PMID 19829291 DOI: 10.1038/Npp.2009.158  0.354
2009 Soto PL, Hiranita T, Katz JL. Citalopram enhances cocaine's subjective effects in rats. Behavioural Pharmacology. 20: 759-62. PMID 20195220 DOI: 10.1097/Fbp.0B013E328333A267  0.679
2009 Hiranita T, Soto PL, Newman AH, Katz JL. Assessment of reinforcing effects of benztropine analogs and their effects on cocaine self-administration in rats: comparisons with monoamine uptake inhibitors. The Journal of Pharmacology and Experimental Therapeutics. 329: 677-86. PMID 19228996 DOI: 10.1124/Jpet.108.145813  0.715
2008 Hiranita T, Nawata Y, Sakimura K, Yamamoto T. Methamphetamine-seeking behavior is due to inhibition of nicotinic cholinergic transmission by activation of cannabinoid CB1 receptors. Neuropharmacology. 55: 1300-6. PMID 18782581 DOI: 10.1016/J.Neuropharm.2008.08.012  0.434
2008 Uchiyama H, Yamaguchi T, Toda A, Hiranita T, Watanabe S, Eyanagi R. Involvement of the GABA/benzodiazepine receptor in the axiolytic-like effect of nociceptin/orphanin FQ. European Journal of Pharmacology. 590: 185-9. PMID 18586237 DOI: 10.1016/J.Ejphar.2008.05.031  0.37
2008 Uchiyama H, Toda A, Hiranita T, Watanabe S, Eyanagi R. Role of amygdaloid nuclei in the anxiolytic-like effect of nociceptin/orphanin FQ in rats. Neuroscience Letters. 431: 66-70. PMID 18166271 DOI: 10.1016/J.Neulet.2007.11.023  0.332
2006 Hiranita T, Nawata Y, Sakimura K, Anggadiredja K, Yamamoto T. Suppression of methamphetamine-seeking behavior by nicotinic agonists. Proceedings of the National Academy of Sciences of the United States of America. 103: 8523-7. PMID 16717181 DOI: 10.1073/Pnas.0600347103  0.342
2004 Yamamoto T, Anggadiredja K, Hiranita T. New perspectives in the studies on endocannabinoid and cannabis: a role for the endocannabinoid-arachidonic acid pathway in drug reward and long-lasting relapse to drug taking. Journal of Pharmacological Sciences. 96: 382-8. PMID 15599102 DOI: 10.1254/Jphs.Fmj04003X5  0.354
2004 Hiranita T, Anggadiredja K, Fujisaki C, Watanabe S, Yamamoto T. Nicotine attenuates relapse to methamphetamine-seeking behavior (craving) in rats. Annals of the New York Academy of Sciences. 1025: 504-7. PMID 15542755 DOI: 10.1196/Annals.1316.062  0.349
2004 Anggadiredja K, Sakimura K, Hiranita T, Yamamoto T. Naltrexone attenuates cue- but not drug-induced methamphetamine seeking: a possible mechanism for the dissociation of primary and secondary reward. Brain Research. 1021: 272-6. PMID 15342276 DOI: 10.1016/J.Brainres.2004.06.051  0.523
2004 Anggadiredja K, Nakamichi M, Hiranita T, Tanaka H, Shoyama Y, Watanabe S, Yamamoto T. Endocannabinoid system modulates relapse to methamphetamine seeking: possible mediation by the arachidonic acid cascade. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1470-8. PMID 15085091 DOI: 10.1038/Sj.Npp.1300454  0.528
Low-probability matches (unlikely to be authored by this person)
2023 Hiranita T, Ho NP, France CP. . The Journal of Pharmacology and Experimental Therapeutics. PMID 37739803 DOI: 10.1124/jpet.123.001653  0.296
2020 Obeng S, Wilkerson JL, León F, Reeves ME, Restrepo LF, Gamez-Jimenez LR, Patel A, Pennington AE, Taylor VA, Ho NP, Braun T, Fortner JD, Crowley ML, Williamson MR, Pallares VL, ... ... Hiranita T, et al. Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy for Mu-Opioid Receptor and Opioid-Like Behavioral Effects in Rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 33384303 DOI: 10.1124/jpet.120.000189  0.287
2021 León F, Obeng S, Mottinelli M, Chen Y, King TI, Berthold EC, Kamble SH, Restrepo LF, Patel A, Gamez-Jimenez LR, Lopera-Londoño C, Hiranita T, Sharma A, Hampson AJ, Canal CE, et al. Activity of ("Kratom") Alkaloids at Serotonin Receptors. Journal of Medicinal Chemistry. PMID 34467758 DOI: 10.1021/acs.jmedchem.1c00726  0.285
2015 Goodwin AK, Hiranita T, Paule MG. The Reinforcing Effects of Nicotine in Humans and Nonhuman Primates: A Review of Intravenous Self-Administration Evidence and Future Directions for Research. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 25673111 DOI: 10.1093/Ntr/Ntv002  0.283
2008 Sakae N, Yamasaki N, Kitaichi K, Fukuda T, Yamada M, Yoshikawa H, Hiranita T, Tatsumi Y, Kira J, Yamamoto T, Miyakawa T, Nakayama KI. Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants. Human Molecular Genetics. 17: 3191-203. PMID 18647754 DOI: 10.1093/Hmg/Ddn215  0.282
2020 Hong WC, Sharma A, Hiranita T, Avery BA, McCurdy CR. Potential biochemical mechanisms of the dual sigma‐1 and dopamine transporter ligand CM699 The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06580  0.277
2024 Hiranita T, Ho NP, France CP. µ. The Journal of Pharmacology and Experimental Therapeutics. PMID 38409115 DOI: 10.1124/jpet.123.002032  0.274
2015 Hiranita T. Self-Administration of an Endogenous Cannabinoid 2-Arachidonoylglycerol in Experimentally Naïve Rats. Journal of Alcoholism and Drug Dependence. 3. PMID 27376099 DOI: 10.4172/2329-6488.1000e126  0.272
2022 Wilkerson JL, Hiranita T, Koek W, McMahon LR. The discriminative stimulus effects of baclofen and gamma hydroxybutyrate in C57BL/6J mice. Behavioural Pharmacology. 33: 427-434. PMID 35947069 DOI: 10.1097/FBP.0000000000000691  0.271
2015 Hiranita T. Medications Discovery: Importance of Assessment of Drug Self Administration Dose-Effect Curves. Journal of Alcoholism and Drug Dependence. 3. PMID 27413771  0.27
2015 Hiranita T. Self-Administration of JWH-018 A Synthetic Cannabinoid in Experimentally Naïve Rats. Journal of Alcoholism and Drug Dependence. 3. PMID 27398395 DOI: 10.4172/2329-6488.1000e128  0.268
2023 Kamble SH, Obeng S, León F, Restrepo LF, King TI, Berthold EC, Kanumuri SRR, Gamez-Jimenez LR, Pallares VL, Patel A, Ho NP, Hampson A, McCurdy CR, McMahon LR, Wilkerson JL, ... ... Hiranita T, et al. . The Journal of Pharmacology and Experimental Therapeutics. PMID 37019472 DOI: 10.1124/jpet.122.001525  0.263
2021 Berthold EC, Kamble SH, Raju KS, Kuntz MA, Senetra AS, Mottinelli M, León F, Restrepo LF, Patel A, Ho NP, Hiranita T, Sharma A, McMahon LR, McCurdy CR. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 34759012 DOI: 10.1124/dmd.121.000640  0.263
2020 Obeng S, Patel A, Burns M, Intagliata S, Mottinelli M, Reeves ME, Behnke M, Restrepo LF, Ho NP, Gamez Jimenez LR, Williamson MR, McCurdy CR, McMahon LR, Hiranita T. The Sigma 1 Receptor Antagonist CM304 Potentiates the Antinociceptive but not the Discriminative Stimulus Effects of the Cannabinoid Receptor Agonist THC in Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05381  0.261
2005 Sakimura K, Hiranita T, Miyamoto M, Nagata K, Yamamoto T. [Drug-craving animal models and mechanisms]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 126: 24-9, 23. PMID 16141614 DOI: 10.1254/Fpj.126.24  0.261
2021 Hiranita T, Obeng S, Sharma A, Wilkerson JL, McCurdy CR, McMahon LR. In vitro and in vivo pharmacology of kratom. Advances in Pharmacology (San Diego, Calif.). 93: 35-76. PMID 35341571 DOI: 10.1016/bs.apha.2021.10.001  0.248
2015 Hiranita T, Thorn DA. Trace Amine-Associated Receptor Type 1 as A Target for The Development of Treatments for Stimulant Abuse. Journal of Alcoholism and Drug Dependence. 3. PMID 27390752  0.246
2020 Patel A, Obeng S, Burns M, Intagliata S, Mottinelli M, Reeves ME, Behnke M, Restrepo LF, Taylor VA, Pennington AE, Gamez Jimenez LR, Williamson MR, McCurdy CR, McMahon LR, Hiranita T. The Sigma 1 Receptor Antagonist CM304 Enhances the Antinociceptive Effects of the Cannabinoid Receptor Agonists, but not Mu‐Opioid Receptor Full Agonists in Mice The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05719  0.241
2017 Naylor JE, Hiranita T, Matazel KS, Zhang X, Paule MG, Goodwin AK. Positron emission tomography (PET) imaging of nicotine-induced dopamine release in squirrel monkeys using [(18)F]Fallypride. Drug and Alcohol Dependence. 179: 254-259. PMID 28818716 DOI: 10.1016/J.Drugalcdep.2017.07.013  0.238
2020 de Moura FB, Hiranita T, McMahon LR. The discriminative stimulus effects of epibatidine in C57BL/6J mice. Behavioural Pharmacology. PMID 32209809 DOI: 10.1097/Fbp.0000000000000555  0.235
2019 Hiranita T, Leon F, Felix JS, Restrepo LF, Reeves ME, Pennington AE, Obeng S, Avery BA, McCurdy CR, McMahon LR, Wilkerson JL. The effects of mitragynine and morphine on schedule-controlled responding and antinociception in rats. Psychopharmacology. PMID 31098655 DOI: 10.1007/S00213-019-05247-7  0.222
2019 Obeng S, Kamble SH, Reeves ME, Restrepo LF, Patel A, Behnke M, Chear N, Ramanathan S, Sharma A, Leon F, Hiranita T, Avery BA, McMahon LR, McCurdy CR. Investigation of the Adrenergic and Opioid Binding affinities, Metabolic Stability, Plasma Protein Binding Properties and Functional Effects of Selected Indole-based Kratom Alkaloids. Journal of Medicinal Chemistry. PMID 31834797 DOI: 10.1021/Acs.Jmedchem.9B01465  0.211
2022 Wilson CD, Hiranita T, Fantegrossi WE. Cannabimimetic effects of abused indazole-carboxamide synthetic cannabinoid receptor agonists AB-PINACA, 5F-AB-PINACA and 5F-ADB-PINACA in mice: Tolerance, dependence and withdrawal. Drug and Alcohol Dependence. 236: 109468. PMID 35643039 DOI: 10.1016/j.drugalcdep.2022.109468  0.21
2021 Chear NJ, León F, Sharma A, Kanumuri SRR, Zwolinski G, Abboud KA, Singh D, Restrepo LF, Patel A, Hiranita T, Ramanathan S, Hampson AJ, McMahon LR, McCurdy CR. Exploring the Chemistry of Alkaloids from Malaysian (Kratom) and the Role of Oxindoles on Human Opioid Receptors. Journal of Natural Products. PMID 33635670 DOI: 10.1021/acs.jnatprod.0c01055  0.2
2006 Nakahara H, Nakamura S, Hiranita T, Kawasaki H, Lee S, Sugihara G, Shibata O. Mode of interaction of amphiphilic alpha-helical peptide with phosphatidylcholines at the air-water interface. Langmuir : the Acs Journal of Surfaces and Colloids. 22: 1182-92. PMID 16430282 DOI: 10.1021/La0524925  0.195
2016 Hiranita T. Identification of Antagonists Selective for Sigma Receptor Subtypes that are Active In vivo. Journal of Alcoholism and Drug Dependence. 4. PMID 27588298  0.194
2021 Obeng S, Hiranita T, León F, McMahon LR, McCurdy CR. Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery. Journal of Medicinal Chemistry. PMID 33956427 DOI: 10.1021/acs.jmedchem.1c00028  0.187
2023 Shahbazi Nia S, Hossain MA, Ji G, Jonnalagadda SK, Obeng S, Rahman MA, Sifat AE, Nozohouri S, Blackwell C, Patel D, Thompson J, Runyon S, Hiranita T, McCurdy CR, McMahon L, et al. Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands. European Journal of Medicinal Chemistry. 254: 115309. PMID 37054561 DOI: 10.1016/j.ejmech.2023.115309  0.187
2021 Crowley ML, Restrepo LF, Gamez-Jimenez LR, Patel A, Braun T, Pallares VLC, Ho NP, McCurdy CR, McMahon LR, Hiranita T. The use of hypercapnic conditions to assess opioid-induced respiratory depression in rats. Journal of Pharmacological and Toxicological Methods. 107101. PMID 34242797 DOI: 10.1016/j.vascn.2021.107101  0.177
2021 Crowley ML, Restrepo LF, Gamez-Jimenez LR, Patel A, Braun T, Pallares VLC, Ho NP, McCurdy CR, McMahon LR, Hiranita T. The use of hypercapnic conditions to assess opioid-induced respiratory depression in rats. Journal of Pharmacological and Toxicological Methods. 107101. PMID 34242797 DOI: 10.1016/j.vascn.2021.107101  0.177
2016 Hiranita T, Freyberg Z. Importance of Substrate-Coupled Proton Antiport by the Vesicular Monoamine Transporter in the Actions of Amphetamines in Drosophila Brain. Journal of Alcoholism and Drug Dependence. 4. PMID 28164142 DOI: 10.4172/2329-6488.1000E136  0.171
2016 Hiranita T. Identification of the Sigma-2 Receptor: Distinct from the Progesterone Receptor Membrane Component 1 (PGRMC1). Journal of Alcoholism and Drug Dependence. 4. PMID 27376101  0.149
2020 Reeve ME, Obeng S, Oyola FL, Behnke M, Restrepo LF, Patel A, Ho NP, Williamson MR, Gamez Jimenez LR, McCurdy CR, McMahon LR, Hiranita T. The Adrenergic a 2 Receptor‐Mediated Discriminative‐Stimulus Effects of Mitragynine, the Primary Alkaloid in Kratom ( Mitragyna Speciosa ) in Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05233  0.132
2015 Hiranita T. In Vivo Significance of In Vitro Studies on G-Protein-Coupled Receptor Heteromers. Journal of Alcoholism and Drug Dependence. 3. PMID 27377120 DOI: 10.4172/2329-6488.1000e120  0.124
2019 McMahon LR, Hiranita T, Wilkerson JL, Oyala JFL, McCurdy CR. Pharmacological characterization of mitragynine, the primary constituent in Kratom, as a potential medication for opioid use disorder. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31963089 DOI: 10.1016/J.Vascn.2019.05.012  0.116
2016 Hiranita T. (-)-Trans-Δ(9)-Tetrahydrocannabinol-Like Discriminative-Stimulus Effects of Gabapentin in Cannabis Users. Journal of Alcoholism and Drug Dependence. 4. PMID 27376100  0.109
2005 Sakimura K, Hiranita T, Miyamoto M, Nagata K, Yamamoto T. Drug-craving-aninal models and mechanisms Folia Pharmacologica Japonica. 126: 24-29. DOI: 10.1254/fpj.126.24  0.109
2020 Hiranita T, Sharma A, Oyola FL, Obeng S, Reeves ME, Restrepo LF, Patel A, Behnke M, Ho NP, Williamson MR, Gamez Jimenez LR, McCurdy CR, McMahon LR. Potential Contribution of 7‐Hydroxymitragynine, a Metabolite of the Primary Kratom ( Mitragyna Speciosa ) Alkaloid Mitragynine, to the μ‐Opioid Activity of Mitragynine in Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05180  0.105
2021 Obeng S, Hiranita T, León F, McMahon LR, McCurdy CR. Correction to "Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery". Journal of Medicinal Chemistry. PMID 34264657 DOI: 10.1021/acs.jmedchem.1c01159  0.082
2021 Obeng S, Hiranita T, León F, McMahon LR, McCurdy CR. Correction to "Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery". Journal of Medicinal Chemistry. PMID 34264657 DOI: 10.1021/acs.jmedchem.1c01159  0.082
2014 Hiranita T. Role of the σRs for Development of Medications. Journal of Alcoholism and Drug Dependence. 2. PMID 27398392 DOI: 10.4172/2329-6488.1000e109  0.029
2003 Hiranita T, Nakamura S, Kawachi M, Courrier HM, Vandamme TF, Krafft MP, Shibata O. Miscibility behavior of dipalmitoylphosphatidylcholine with a single-chain partially fluorinated amphiphile in Langmuir monolayers. Journal of Colloid and Interface Science. 265: 83-92. PMID 12927168 DOI: 10.1016/S0021-9797(03)00483-1  0.024
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