Year |
Citation |
Score |
2023 |
Spafford JD. A governance of ion selectivity based on the occupancy of the "beacon" in one- and four-domain calcium and sodium channels. Channels (Austin, Tex.). 17: 2191773. PMID 37075164 DOI: 10.1080/19336950.2023.2191773 |
0.601 |
|
2022 |
Guan W, Orellana KG, Stephens RF, Zhorov BS, Spafford JD. A lysine residue from an extracellular turret switches the ion preference in a Cav3 T-Type channel from calcium to sodium ions. The Journal of Biological Chemistry. 102621. PMID 36272643 DOI: 10.1016/j.jbc.2022.102621 |
0.468 |
|
2020 |
Segura E, Mehta A, Marsolais M, Quan XR, Zhao J, Sauvé R, Spafford JD, Parent L. An ancestral maguk protein supports the modulation of mammalian voltage-gated Ca channels through a conserved Caβ-like interface. Biochimica Et Biophysica Acta. Biomembranes. 183439. PMID 32814116 DOI: 10.1016/J.Bbamem.2020.183439 |
0.576 |
|
2020 |
Guan W, Stephens RF, Mourad O, Mehta A, Fux J, Spafford JD. Unique cysteine-enriched, D2L5 and D4L6 extracellular loops in Ca3 T-type channels alter the passage and block of monovalent and divalent ions. Scientific Reports. 10: 12404. PMID 32710088 DOI: 10.1038/S41598-020-69197-3 |
0.607 |
|
2020 |
Segura E, Mehta A, Marsolais M, Quan XR, Zhao J, Sauvé R, Spafford JD, Parent L. Unicellular CaVβ Subunit Modulates Calcium Channels Biophysical Journal. 118: 107a. DOI: 10.1016/J.Bpj.2019.11.735 |
0.558 |
|
2018 |
Fux JE, Mehta A, Moffat J, Spafford JD. Eukaryotic Voltage-Gated Sodium Channels: On Their Origins, Asymmetries, Losses, Diversification and Adaptations. Frontiers in Physiology. 9: 1406. PMID 30519187 DOI: 10.3389/Fphys.2018.01406 |
0.691 |
|
2017 |
Chemin J, Taiakina V, Monteil A, Piazza M, Guan W, Stephens RF, Kitmitto A, Pang ZP, Dolphin AC, Perez-Reyes E, Dieckmann T, Guillemette JG, Spafford JD. Calmodulin regulates Cav3 T-type channels at their gating brake. The Journal of Biological Chemistry. PMID 28972185 DOI: 10.1074/Jbc.M117.807925 |
0.655 |
|
2015 |
Stephens RF, Guan W, Zhorov BS, Spafford JD. Selectivity filters and cysteine-rich extracellular loops in voltage-gated sodium, calcium, and NALCN channels. Frontiers in Physiology. 6: 153. PMID 26042044 DOI: 10.3389/Fphys.2015.00153 |
0.655 |
|
2015 |
Senatore A, Spafford JD. Physiology and pathology of voltage-gated t-type calcium channels T-Type Calcium Channels in Basic and Clinical Science. 3-17. DOI: 10.1007/978-3-7091-1413-1_1 |
0.73 |
|
2014 |
Boone AN, Senatore A, Chemin J, Monteil A, Spafford JD. Gd3+ and calcium sensitive, sodium leak currents are features of weak membrane-glass seals in patch clamp recordings. Plos One. 9: e98808. PMID 24945283 DOI: 10.1371/Journal.Pone.0098808 |
0.677 |
|
2014 |
Dawson TF, Boone AN, Senatore A, Piticaru J, Thiyagalingam S, Jackson D, Davison A, Spafford JD. Gene splicing of an invertebrate beta subunit (LCavβ) in the N-terminal and HOOK domains and its regulation of LCav1 and LCav2 calcium channels. Plos One. 9: e92941. PMID 24690951 DOI: 10.1371/Journal.Pone.0092941 |
0.641 |
|
2014 |
Senatore A, Guan W, Boone AN, Spafford JD. T-type channels become highly permeable to sodium ions using an alternative extracellular turret region (S5-P) outside the selectivity filter. The Journal of Biological Chemistry. 289: 11952-69. PMID 24596098 DOI: 10.1074/Jbc.M114.551473 |
0.778 |
|
2014 |
Senatore A, Guan W, Spafford JD. Cav3 T-type channels: regulators for gating, membrane expression, and cation selectivity. PflüGers Archiv : European Journal of Physiology. 466: 645-60. PMID 24515291 DOI: 10.1007/S00424-014-1449-7 |
0.776 |
|
2014 |
Guan W, Stephens RF, Spafford JD. Cav3 T-type channels as drug targets for treating epilepsy Future Neurology. 9: 563-566. DOI: 10.2217/Fnl.14.42 |
0.32 |
|
2014 |
Taiakina V, Boone AN, Fux J, Senatore A, Weber-Adrian D, Guillemette JG, Spafford JD. Correction: The calmodulin-binding, short linear motif, NSCaTE is conserved in L-type channel ancestors of vertebrate Cav1.2 and Cav1.3 channels (PLoS ONE) Plos One. 9. DOI: 10.1371/annotation/7fc1cd8d-1eeb-4ab7-929b-96529cab1c1f |
0.719 |
|
2013 |
Taiakina V, Boone AN, Fux J, Senatore A, Weber-Adrian D, Guillemette JG, Spafford JD. The calmodulin-binding, short linear motif, NSCaTE is conserved in L-type channel ancestors of vertebrate Cav1.2 and Cav1.3 channels. Plos One. 8: e61765. PMID 23626724 DOI: 10.1371/Journal.Pone.0061765 |
0.727 |
|
2013 |
Senatore A, Spafford JD. A uniquely adaptable pore is consistent with NALCN being an ion sensor. Channels (Austin, Tex.). 7: 60-8. PMID 23442378 DOI: 10.4161/Chan.23981 |
0.727 |
|
2013 |
Senatore A, Monteil A, van Minnen J, Smit AB, Spafford JD. NALCN ion channels have alternative selectivity filters resembling calcium channels or sodium channels. Plos One. 8: e55088. PMID 23383067 DOI: 10.1371/Journal.Pone.0055088 |
0.773 |
|
2013 |
Senatore A, Spafford JD. Correction: Gene Transcription and Splicing of T-Type Channels Are Evolutionarily-Conserved Strategies for Regulating Channel Expression and Gating Plos One. 8. DOI: 10.1371/annotation/9d69fd63-4378-4e05-b2ad-2a5c98561223 |
0.561 |
|
2012 |
Senatore A, Spafford JD. Gene transcription and splicing of T-type channels are evolutionarily-conserved strategies for regulating channel expression and gating. Plos One. 7: e37409. PMID 22719839 DOI: 10.1371/Journal.Pone.0037409 |
0.758 |
|
2012 |
Senatore A, Zhorov BS, Spafford JD. Cav3 T-type calcium channels Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 1: 467-491. DOI: 10.1002/wmts.41 |
0.711 |
|
2011 |
Senatore A, Boone A, Lam S, Dawson TF, Zhorov B, Spafford JD. Mapping of dihydropyridine binding residues in a less sensitive invertebrate L-type calcium channel (LCa v 1). Channels (Austin, Tex.). 5: 173-87. PMID 21487241 DOI: 10.4161/Chan.5.2.15141 |
0.726 |
|
2011 |
Senatore A, Boone AN, Spafford JD. Optimized transfection strategy for expression and electrophysiological recording of recombinant voltage-gated ion channels in HEK-293T cells. Journal of Visualized Experiments : Jove. PMID 21304463 DOI: 10.3791/2314 |
0.675 |
|
2010 |
Huang X, Senatore A, Dawson TF, Quan Q, Spafford JD. G-proteins modulate invertebrate synaptic calcium channel (LCav2) differently from the classical voltage-dependent regulation of mammalian Cav2.1 and Cav2.2 channels. The Journal of Experimental Biology. 213: 2094-103. PMID 20511524 DOI: 10.1242/Jeb.042242 |
0.689 |
|
2010 |
Senatore A, Spafford JD. Transient and big are key features of an invertebrate T-type channel (LCav3) from the central nervous system of Lymnaea stagnalis. The Journal of Biological Chemistry. 285: 7447-58. PMID 20056611 DOI: 10.1074/Jbc.M109.090753 |
0.78 |
|
2008 |
Zhang Y, Helm JS, Senatore A, Spafford JD, Kaczmarek LK, Jonas EA. PKC-induced intracellular trafficking of Ca(V)2 precedes its rapid recruitment to the plasma membrane. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2601-12. PMID 18322103 DOI: 10.1523/Jneurosci.4314-07 |
0.636 |
|
2008 |
Flynn R, Chen L, Hameed S, Spafford JD, Zamponi GW. Molecular determinants of Rem2 regulation of N-type calcium channels. Biochemical and Biophysical Research Communications. 368: 827-31. PMID 18279668 DOI: 10.1016/J.Bbrc.2008.02.020 |
0.559 |
|
2006 |
van Nierop P, Bertrand S, Munno DW, Gouwenberg Y, van Minnen J, Spafford JD, Syed NI, Bertrand D, Smit AB. Identification and functional expression of a family of nicotinic acetylcholine receptor subunits in the central nervous system of the mollusc Lymnaea stagnalis. The Journal of Biological Chemistry. 281: 1680-91. PMID 16286458 DOI: 10.1074/Jbc.M508571200 |
0.333 |
|
2006 |
Spafford JD, Dunn T, Smit AB, Syed NI, Zamponi GW. In vitro characterization of L-type calcium channels and their contribution to firing behavior in invertebrate respiratory neurons. Journal of Neurophysiology. 95: 42-52. PMID 16162826 DOI: 10.1152/Jn.00658.2005 |
0.613 |
|
2004 |
Spafford JD, Van Minnen J, Larsen P, Smit AB, Syed NI, Zamponi GW. Uncoupling of calcium channel alpha1 and beta subunits in developing neurons. The Journal of Biological Chemistry. 279: 41157-67. PMID 15265869 DOI: 10.1074/Jbc.M403781200 |
0.549 |
|
2003 |
Spafford JD, Zamponi GW. Functional interactions between presynaptic calcium channels and the neurotransmitter release machinery. Current Opinion in Neurobiology. 13: 308-14. PMID 12850215 DOI: 10.1016/S0959-4388(03)00061-8 |
0.485 |
|
2003 |
Szule JA, Jarvis SE, Hibbert JE, Spafford JD, Braun JE, Zamponi GW, Wessel GM, Coorssen JR. Calcium-triggered membrane fusion proceeds independently of specific presynaptic proteins. The Journal of Biological Chemistry. 278: 24251-4. PMID 12764142 DOI: 10.1074/Jbc.C300197200 |
0.314 |
|
2003 |
Spafford JD, Chen L, Feng ZP, Smit AB, Zamponi GW. Expression and modulation of an invertebrate presynaptic calcium channel alpha1 subunit homolog. The Journal of Biological Chemistry. 278: 21178-87. PMID 12672808 DOI: 10.1074/Jbc.M302212200 |
0.671 |
|
2003 |
Feng ZP, Doering CJ, Winkfein RJ, Beedle AM, Spafford JD, Zamponi GW. Determinants of inhibition of transiently expressed voltage-gated calcium channels by omega-conotoxins GVIA and MVIIA. The Journal of Biological Chemistry. 278: 20171-8. PMID 12654924 DOI: 10.1074/Jbc.M300581200 |
0.682 |
|
2003 |
Spafford JD, Munno DW, Van Nierop P, Feng ZP, Jarvis SE, Gallin WJ, Smit AB, Zamponi GW, Syed NI. Calcium channel structural determinants of synaptic transmission between identified invertebrate neurons. The Journal of Biological Chemistry. 278: 4258-67. PMID 12458203 DOI: 10.1074/Jbc.M211076200 |
0.74 |
|
1999 |
Spafford JD, Spencer AN, Gallin WJ. Genomic organization of a voltage-gated Na+ channel in a hydrozoan jellyfish: insights into the evolution of voltage-gated Na+ channel genes. Receptors & Channels. 6: 493-506. PMID 10635065 |
0.77 |
|
1999 |
Grigoriev NG, Spafford JD, Spencer AN. Residues in a jellyfish shaker-like channel involved in modulation by external potassium. Journal of Neurophysiology. 82: 1740-7. PMID 10515963 DOI: 10.1152/Jn.1999.82.4.1740 |
0.483 |
|
1999 |
Grigoriev NG, Spafford JD, Spencer AN. Modulation of jellyfish potassium channels by external potassium ions. Journal of Neurophysiology. 82: 1728-39. PMID 10515962 DOI: 10.1152/Jn.1999.82.4.1728 |
0.645 |
|
1999 |
Grigoriev NG, Spafford JD, Spencer AN. The effects of level of expression of a jellyfish Shaker potassium channel: a positive potassium feedback mechanism. The Journal of Physiology. 517: 25-33. PMID 10226146 DOI: 10.1111/j.1469-7793.1999.0025z.x |
0.482 |
|
1998 |
Spafford JD, Spencer AN, Gallin WJ. A putative voltage-gated sodium channel alpha subunit (PpSCN1) from the hydrozoan jellyfish, Polyorchis penicillatus: structural comparisons and evolutionary considerations. Biochemical and Biophysical Research Communications. 244: 772-80. PMID 9535741 DOI: 10.1006/bbrc.1998.8332 |
0.743 |
|
1997 |
Grigoriev NG, Spafford JD, Gallin WJ, Spencer AN. Voltage sensing in jellyfish Shaker K+ channels. The Journal of Experimental Biology. 200: 2919-26. PMID 9344982 |
0.738 |
|
1996 |
Spafford J, Grigoriev N, Spencer A. Pharmacological properties of voltage-gated Na+ currents in motor neurones from a hydrozoan jellyfish Polyorchis penicillatus The Journal of Experimental Biology. 199: 941-8. PMID 9318735 |
0.487 |
|
1996 |
Grigoriev NG, Spafford JD, Przysiezniak J, Spencer AN. A cardiac-like sodium current in motor neurons of a jellyfish. Journal of Neurophysiology. 76: 2240-9. PMID 8899599 |
0.407 |
|
Low-probability matches (unlikely to be authored by this person) |
1996 |
Spafford JD, Grigoriev NG, Spencer AN. Pharmacological properties of voltage-gated Na+ currents in motor neurones from a hydrozoan jellyfish Polyorchis penicillatus Journal of Experimental Biology. 199: 941-948. |
0.223 |
|
2021 |
Wallis A, Yannuzzi IM, Choi MW, Spafford J, Siemon M, Ramachandran P, Timme R, Pettengill J, Cagle R, Ottesen AR, Cox K. Investigating the distribution of strains of Erwinia amylovora and streptomycin resistance in apple orchards in New York using CRISPR profiles: a six-year follow-up. Plant Disease. PMID 33599513 DOI: 10.1094/PDIS-12-20-2585-RE |
0.036 |
|
2022 |
Spafford J. Self-Ownership and the Duty to Assist. Journal of Applied Philosophy. 39: 857-869. PMID 36589900 DOI: 10.1111/japp.12595 |
0.023 |
|
2012 |
Hashmi A, Xu Y, Coder B, Osborne PA, Spafford J, Michael GE, Yu G, Xu J. Leidenfrost levitation: beyond droplets. Scientific Reports. 2: 797. PMID 23150770 DOI: 10.1038/Srep00797 |
0.016 |
|
2021 |
Moffat J, Copas C, Wood K, Spafford JD. Asynchronous Delivery of a 400 Level, Partially Peer-Graded, Oral Presentation and Discussion Course in Systems Neuroscience for 60 Students during the COVID-19 Pandemic. Brain Sciences. 11. PMID 34070393 DOI: 10.3390/brainsci11060693 |
0.01 |
|
2006 |
Snowden S, Spafford J, Michaelides R, Hopkins J. Technology acceptance and m‐commerce in an operational environment Journal of Enterprise Information Management. 19: 525-539. DOI: 10.1108/17410390610703657 |
0.01 |
|
Hide low-probability matches. |