James R. Howe - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
Glutamate Receptors

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Devi SPS, Cheng Y, Tomita S, Howe JR, Zhang W. TARPs Modulate Receptor-Mediated Paired-Pulse Depression and Recovery from Desensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32994336 DOI: 10.1523/JNEUROSCI.3026-19.2020  0.328
2018 Goffredo P, Utria AF, Beck AC, Chun YS, Howe JR, Weigel RJ, Vauthey JN, Hassan I. The Prognostic Impact of KRAS Mutation in Patients Having Curative Resection of Synchronous Colorectal Liver Metastases. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. PMID 30276588 DOI: 10.1007/s11605-018-3978-4  0.305
2018 Levy AD, Xiao X, Shaw JE, Sudarsana Devi SP, Katrancha SM, Bennett AM, Greer CA, Howe JR, Machida K, Koleske AJ. Noonan Syndrome-Associated SHP2 Dephosphorylates GluN2B to Regulate NMDA Receptor Function. Cell Reports. 24: 1523-1535. PMID 30089263 DOI: 10.1016/J.Celrep.2018.07.006  0.344
2017 Keck KJ, Breheny P, Braun TA, Darbro B, Li G, Dillon JS, Bellizzi AM, O'Dorisio TM, Howe JR. Changes in gene expression in small bowel neuroendocrine tumors associated with progression to metastases. Surgery. PMID 29154080 DOI: 10.1016/J.Surg.2017.07.031  0.3
2017 Choi AB, Maxwell JE, Keck KJ, Bellizzi AJ, Dillon JS, OʼDorisio TM, Howe JR. Is Multifocality an Indicator of Aggressive Behavior in Small Bowel Neuroendocrine Tumors? Pancreas. 46: 1115-1120. PMID 28902780 DOI: 10.1097/MPA.0000000000000911  0.324
2017 Zhang W, Eibl C, Weeks AM, Riva I, Li YJ, Plested AJR, Howe JR. Unitary Properties of AMPA Receptors with Reduced Desensitization. Biophysical Journal. PMID 28863863 DOI: 10.1016/J.Bpj.2017.07.030  0.453
2017 Lee JP, Hung YP, O'Dorisio TM, Howe JR, Hornick JL, Bellizzi AM. Examination of PHOX2B in Adult Neuroendocrine Neoplasms Reveals Relatively Frequent Expression in Pheochromocytomas and Paragangliomas. Histopathology. PMID 28464318 DOI: 10.1111/His.13243  0.309
2016 Maxwell JE, Sherman SK, Howe JR. Translational Diagnostics and Therapeutics in Pancreatic Neuroendocrine Tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 22: 5022-5029. PMID 27742788 DOI: 10.1158/1078-0432.CCR-16-0435  0.323
2016 Straub C, Noam Y, Nomura T, Yamasaki M, Yan D, Fernandes HB, Zhang P, Howe JR, Watanabe M, Contractor A, Tomita S. Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor. Cell Reports. PMID 27346345 DOI: 10.1016/J.Celrep.2016.05.093  0.346
2016 Sudarsana Devi SP, Howe JR, Auger C. Train stimulation of parallel fibre to Purkinje cell inputs reveals two populations of synaptic responses with different receptor signatures. The Journal of Physiology. PMID 27094216 DOI: 10.1113/JP272415  0.317
2016 Han L, Howe JR, Pickering DS. Neto2 Influences on Kainate Receptor Pharmacology and Function. Basic & Clinical Pharmacology & Toxicology. PMID 26928870 DOI: 10.1111/bcpt.12575  0.307
2015 Maxwell JE, Sherman SK, Li G, Choi AB, Bellizzi AM, O'Dorisio TM, Howe JR. Somatic alterations of CDKN1B are associated with small bowel neuroendocrine tumors. Cancer Genetics. PMID 26603463 DOI: 10.1016/j.cancergen.2015.08.003  0.303
2015 Howe JR. Auxiliary subunits highlight a role for the LBD-TMD linkers in glutamate receptor desensitization. The Journal of Physiology. 593: 4813-4. PMID 26576775 DOI: 10.1113/JP271434  0.382
2015 Howe JR. Modulation of non-NMDA receptor gating by auxiliary subunits. The Journal of Physiology. 593: 61-72. PMID 25556788 DOI: 10.1113/jphysiol.2014.273904  0.419
2014 Maxwell JE, Sherman SK, Stashek KM, O'Dorisio TM, Bellizzi AM, Howe JR. A practical method to determine the site of unknown primary in metastatic neuroendocrine tumors. Surgery. 156: 1359-65; discussion . PMID 25456909 DOI: 10.1016/J.Surg.2014.08.008  0.301
2014 MacLean DM, Ramaswamy SS, Du M, Howe JR, Jayaraman V. Stargazin promotes closure of the AMPA receptor ligand-binding domain. The Journal of General Physiology. 144: 503-12. PMID 25422502 DOI: 10.1085/Jgp.201411287  0.342
2014 Sherman SK, Maxwell JE, Carr JC, Wang D, Bellizzi AM, Sue O'Dorisio M, O'Dorisio TM, Howe JR. Gene expression accurately distinguishes liver metastases of small bowel and pancreas neuroendocrine tumors. Clinical & Experimental Metastasis. 31: 935-44. PMID 25241033 DOI: 10.1007/s10585-014-9681-2  0.324
2014 Maxwell JE, Sherman SK, Menda Y, Wang D, O'Dorisio TM, Howe JR. Limitations of somatostatin scintigraphy in primary small bowel neuroendocrine tumors. The Journal of Surgical Research. 190: 548-53. PMID 24950794 DOI: 10.1016/J.Jss.2014.05.031  0.323
2014 Zhang W, Devi SP, Tomita S, Howe JR. Auxiliary proteins promote modal gating of AMPA- and kainate-type glutamate receptors. The European Journal of Neuroscience. 39: 1138-47. PMID 24712993 DOI: 10.1111/Ejn.12519  0.439
2014 Sherman SK, Maxwell JE, Carr JC, Wang D, O'Dorisio MS, O'Dorisio TM, Howe JR. GIPR expression in gastric and duodenal neuroendocrine tumors. The Journal of Surgical Research. 190: 587-93. PMID 24565507 DOI: 10.1016/J.Jss.2014.01.044  0.325
2014 Maxwell J, Sherman S, Wang D, Menda Y, O'Dorisio T, Howe J. Factors Associated with Success of Somatostatin Receptor Scintigraphy to Localize the Primary in Small Bowel Neuroendocrine Tumors Journal of Surgical Research. 186: 506. DOI: 10.1016/j.jss.2013.11.235  0.346
2014 Sherman S, Maxwell J, Carr J, Wang D, O'Dorisio M, O'Dorisio T, Howe J. High Expression of Somatostatin Type 2 Receptor (SSTR2) and Gastric Inhibitory Polypeptide Receptor (GIPR) in Stomach and Duodenal Neuroendocrine Tumors (NETs) Journal of Surgical Research. 186: 506. DOI: 10.1016/j.jss.2013.11.229  0.351
2014 Zhang W, Howe J. Recovery of AMPA Receptor GluA1 is Modulate by TARPs Biophysical Journal. 106: 150a. DOI: 10.1016/j.bpj.2013.11.865  0.373
2013 Sherman SK, Carr JC, Wang D, O'Dorisio MS, O'Dorisio TM, Howe JR. Gastric inhibitory polypeptide receptor (GIPR) is a promising target for imaging and therapy in neuroendocrine tumors. Surgery. 154: 1206-13; discussion . PMID 24238043 DOI: 10.1016/j.surg.2013.04.052  0.345
2013 Carr JC, Sherman SK, Wang D, Dahdaleh FS, Bellizzi AM, O'Dorisio MS, O'Dorisio TM, Howe JR. Overexpression of membrane proteins in primary and metastatic gastrointestinal neuroendocrine tumors. Annals of Surgical Oncology. 20: S739-46. PMID 24114056 DOI: 10.1245/s10434-013-3318-6  0.331
2013 Howe JR. CrossTalk proposal: TARPs modulate AMPA receptor gating transitions. The Journal of Physiology. 591: 1581-3; discussion 1. PMID 23547186 DOI: 10.1113/jphysiol.2012.247486  0.316
2013 Bodei L, Mueller-Brand J, Baum RP, Pavel ME, Hörsch D, O'Dorisio MS, O'Dorisio TM, O'Dorisiol TM, Howe JR, Cremonesi M, Kwekkeboom DJ, Zaknun JJ. The joint IAEA, EANM, and SNMMI practical guidance on peptide receptor radionuclide therapy (PRRNT) in neuroendocrine tumours. European Journal of Nuclear Medicine and Molecular Imaging. 40: 800-16. PMID 23389427 DOI: 10.1007/s00259-012-2330-6  0.305
2013 Howe JR. Rebuttal from James Howe Journal of Physiology. 591: 1587. DOI: 10.1113/jphysiol.2012.250449  0.319
2013 MacLean DM, Ramaswamy S, Howe JR, Jayaraman V. Towards a Mechanism of TARP Action at AMPA Receptors Biophysical Journal. 104: 543a. DOI: 10.1016/J.Bpj.2012.11.3007  0.361
2011 Straub C, Zhang W, Howe JR. Neto2 modulation of kainate receptors with different subunit compositions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8078-82. PMID 21632929 DOI: 10.1523/Jneurosci.0024-11.2011  0.436
2009 Zhang W, St-Gelais F, Grabner CP, Trinidad JC, Sumioka A, Morimoto-Tomita M, Kim KS, Straub C, Burlingame AL, Howe JR, Tomita S. A transmembrane accessory subunit that modulates kainate-type glutamate receptors. Neuron. 61: 385-96. PMID 19217376 DOI: 10.1016/J.Neuron.2008.12.014  0.438
2009 Morimoto-Tomita M, Zhang W, Straub C, Cho CH, Kim KS, Howe JR, Tomita S. Autoinactivation of neuronal AMPA receptors via glutamate-regulated TARP interaction. Neuron. 61: 101-12. PMID 19146816 DOI: 10.1016/J.Neuron.2008.11.009  0.445
2009 Howe J. Modulation of AMPA and kainate receptors by accessory subunits Biophysical Journal. 96: 565a. DOI: 10.1016/j.bpj.2008.12.3702  0.364
2008 Zhang W, Howe JR, Popescu GK. Distinct gating modes determine the biphasic relaxation of NMDA receptor currents. Nature Neuroscience. 11: 1373-5. PMID 18953348 DOI: 10.1038/Nn.2214  0.676
2008 Zhang W, Cho Y, Lolis E, Howe JR. Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 932-43. PMID 18216201 DOI: 10.1523/Jneurosci.3309-07.2008  0.435
2007 Cho CH, St-Gelais F, Zhang W, Tomita S, Howe JR. Two families of TARP isoforms that have distinct effects on the kinetic properties of AMPA receptors and synaptic currents. Neuron. 55: 890-904. PMID 17880893 DOI: 10.1016/J.Neuron.2007.08.024  0.428
2006 Howe JR. Desensitization at the interface. Acs Chemical Biology. 1: 623-6. PMID 17168566 DOI: 10.1021/cb6004382  0.351
2006 Sheridan DL, Robert A, Cho CH, Howe JR, Hughes TE. Regions of alpha-amino-5-methyl-3-hydroxy-4-isoxazole propionic acid receptor subunits that are permissive for the insertion of green fluorescent protein. Neuroscience. 141: 837-49. PMID 16765522 DOI: 10.1016/J.Neuroscience.2006.04.052  0.308
2006 Zhang W, Robert A, Vogensen SB, Howe JR. The relationship between agonist potency and AMPA receptor kinetics. Biophysical Journal. 91: 1336-46. PMID 16731549 DOI: 10.1529/Biophysj.106.084426  0.447
2005 Tomita S, Adesnik H, Sekiguchi M, Zhang W, Wada K, Howe JR, Nicoll RA, Bredt DS. Stargazin modulates AMPA receptor gating and trafficking by distinct domains. Nature. 435: 1052-8. PMID 15858532 DOI: 10.1038/Nature03624  0.426
2005 Robert A, Armstrong N, Gouaux JE, Howe JR. AMPA receptor binding cleft mutations that alter affinity, efficacy, and recovery from desensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3752-62. PMID 15829627 DOI: 10.1523/Jneurosci.0188-05.2005  0.35
2004 Popescu G, Robert A, Howe JR, Auerbach A. Reaction mechanism determines NMDA receptor response to repetitive stimulation. Nature. 430: 790-3. PMID 15306812 DOI: 10.1038/nature02775  0.667
2004 Klein RM, Howe JR. Effects of the lurcher mutation on GluR1 desensitization and activation kinetics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4941-51. PMID 15163686 DOI: 10.1523/JNEUROSCI.0660-04.2004  0.548
2003 Robert A, Howe JR. How AMPA receptor desensitization depends on receptor occupancy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 847-58. PMID 12574413 DOI: 10.1523/Jneurosci.23-03-00847.2003  0.411
2002 Robert A, Hyde R, Hughes TE, Howe JR. The expression of dominant-negative subunits selectively suppresses neuronal AMPA and kainate receptors. Neuroscience. 115: 1199-210. PMID 12453491 DOI: 10.1016/S0306-4522(02)00534-1  0.398
2002 Wall MJ, Robert A, Howe JR, Usowicz MM. The speeding of EPSC kinetics during maturation of a central synapse. The European Journal of Neuroscience. 15: 785-97. PMID 11906520 DOI: 10.1046/j.1460-9568.2002.01910.x  0.344
2001 Robert A, Irizarry SN, Hughes TE, Howe JR. Subunit interactions and AMPA receptor desensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5574-86. PMID 11466429 DOI: 10.1523/Jneurosci.21-15-05574.2001  0.727
2000 Goldin AL, Barchi RL, Caldwell JH, Hofmann F, Howe JR, Hunter JC, Kallen RG, Mandel G, Meisler MH, Netter YB, Noda M, Tamkun MM, Waxman SG, Wood JN, Catterall WA. Nomenclature of voltage-gated sodium channels. Neuron. 28: 365-8. PMID 11144347 DOI: 10.1016/S0896-6273(00)00116-1  0.31
2000 Smith TC, Howe JR. Concentration-dependent substate behavior of native AMPA receptors. Nature Neuroscience. 3: 992-7. PMID 11017171 DOI: 10.1038/79931  0.639
2000 Smith TC, Wang LY, Howe JR. Heterogeneous conductance levels of native AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2073-85. PMID 10704481 DOI: 10.1523/Jneurosci.20-06-02073.2000  0.641
2000 Robert A, Howe JR, Waxman SG. Development of glutamatergic synaptic activity in cultured spinal neurons. Journal of Neurophysiology. 83: 659-70. PMID 10669482 DOI: 10.1152/Jn.2000.83.2.659  0.316
1999 Smith TC, Wang LY, Howe JR. Distinct kainate receptor phenotypes in immature and mature mouse cerebellar granule cells. The Journal of Physiology. 517: 51-8. PMID 10226148 DOI: 10.1111/J.1469-7793.1999.0051Z.X  0.645
1999 Howe JR. How glutamate receptors are built Neuroscientist. 5: 311-323. DOI: 10.1177/107385849900500517  0.401
1998 Pemberton KE, Belcher SM, Ripellino JA, Howe JR. High-affinity kainate-type ion channels in rat cerebellar granule cells. The Journal of Physiology. 510: 401-20. PMID 9705992 DOI: 10.1111/J.1469-7793.1998.401Bk.X  0.375
1998 Ripellino JA, Neve RL, Howe JR. Expression and heteromeric interactions of non-N-methyl-D-aspartate glutamate receptor subunits in the developing and adult cerebellum. Neuroscience. 82: 485-97. PMID 9466455 DOI: 10.1016/S0306-4522(97)00296-0  0.338
1998 Cummins TR, Howe JR, Waxman SG. Slow Closed-State Inactivation: A Novel Mechanism Underlying Ramp Currents in Cells Expressing the hNE/PN1 Sodium Channel The Journal of Neuroscience. 18: 9607-9619. DOI: 10.1523/Jneurosci.18-23-09607.1998  0.322
1997 Belcher SM, Howe JR. Characterization of RNA editing of the glutamate-receptor subunits GluR5 and GluR6 in granule cells during cerebellar development. Brain Research. Molecular Brain Research. 52: 130-8. PMID 9450685 DOI: 10.1016/S0169-328X(97)00252-0  0.379
1997 Neve RL, Howe JR, Hong S, Kalb RG. Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus. Neuroscience. 79: 435-47. PMID 9200727 DOI: 10.1016/S0306-4522(96)00645-8  0.356
1996 Moss GW, Marshall J, Morabito M, Howe JR, Moczydlowski E. An evolutionarily conserved binding site for serine proteinase inhibitors in large conductance calcium-activated potassium channels. Biochemistry. 35: 16024-35. PMID 8973172 DOI: 10.1021/bi961452k  0.316
1996 Howe JR. Homomeric and heteromeric ion channels formed from the kainate-type subunits GluR6 and KA2 have very small, but different, unitary conductances. Journal of Neurophysiology. 76: 510-9. PMID 8836240 DOI: 10.1152/Jn.1996.76.1.510  0.342
1996 Carver JM, Mansson PE, Cortes-Burgos L, Shu J, Zhou LM, Howe JR, Giordano T. Cytotoxic effects of kainate ligands on HEK cell lines expressing recombinant kainate receptors. Brain Research. 720: 69-74. PMID 8782898 DOI: 10.1016/0006-8993(96)00115-1  0.368
1995 Belcher SM, Zerillo CA, Levenson R, Ritchie JM, Howe JR. Cloning of a sodium channel alpha subunit from rabbit Schwann cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 11034-8. PMID 7479931 DOI: 10.1073/Pnas.92.24.11034  0.506
1993 Baker M, Howe JR, Ritchie JM. Two types of 4-aminopyridine-sensitive potassium current in rabbit Schwann cells. The Journal of Physiology. 464: 321-42. PMID 8229804 DOI: 10.1113/Jphysiol.1993.Sp019637  0.509
1992 Howe JR, Baker M, Ritchie JM. On the block of outward potassium current in rabbit Schwann cells by internal sodium ions. Proceedings. Biological Sciences / the Royal Society. 249: 309-16. PMID 1359561 DOI: 10.1098/rspb.1992.0120  0.518
1992 Howe JR, Ritchie JM. Multiple kinetic components of sodium channel inactivation in rabbit Schwann cells. The Journal of Physiology. 455: 529-66. PMID 1336556 DOI: 10.1113/Jphysiol.1992.Sp019315  0.512
1991 Howe JR, Ritchie JM. On the active form of 4-aminopyridine: block of K+ currents in rabbit Schwann cells. The Journal of Physiology. 433: 183-205. PMID 1841938 DOI: 10.1113/Jphysiol.1991.Sp018421  0.504
1991 Howe JR, Cull-Candy SG, Colquhoun D. Currents through single glutamate receptor channels in outside-out patches from rat cerebellar granule cells. The Journal of Physiology. 432: 143-202. PMID 1715916 DOI: 10.1113/Jphysiol.1991.Sp018381  0.62
1990 Howe JR, Ritchie JM. Sodium currents in Schwann cells from myelinated and non-myelinated nerves of neonatal and adult rabbits. The Journal of Physiology. 425: 169-210. PMID 2170628 DOI: 10.1113/Jphysiol.1990.Sp018098  0.517
1989 Cull-Candy SG, Howe JR, Usowicz MM. Single glutamate-receptor channels in mammalian cerebellar neurones Fernstrom Foundation Series. 13: 311-328.  0.578
1988 Howe JR, Ritchie JM. Two types of potassium current in rabbit cultured Schwann cells. Proceedings of the Royal Society of London. Series B, Biological Sciences. 235: 19-27. PMID 2467306 DOI: 10.1098/rspb.1988.0061  0.51
1988 Cull-Candy SG, Howe JR, Ogden DC. Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones. The Journal of Physiology. 400: 189-222. PMID 2458453 DOI: 10.1113/Jphysiol.1988.Sp017117  0.602
1988 Howe JR, Colquhoun D, Cull-Candy SG. On the kinetics of large-conductance glutamate-receptor ion channels in rat cerebellar granule neurons. Proceedings of the Royal Society of London. Series B, Biological Sciences. 233: 407-22. PMID 2456583 DOI: 10.1098/rspb.1988.0030  0.607
1987 Howe JR, Yaksh TL, Go VL. The effect of unilateral dorsal root ganglionectomies or ventral rhizotomies on alpha 2-adrenoceptor binding to, and the substance P, enkephalin, and neurotensin content of, the cat lumbar spinal cord. Neuroscience. 21: 385-94. PMID 2441314 DOI: 10.1016/0306-4522(87)90129-1  0.305
1986 Howe JR, Yaksh TL. Characterization of [3H]rauwolscine binding to alpha 2-adrenoceptor sites in the lumbar spinal cord of the cat: comparison to such binding sites in the cat frontal cerebral cortex. Brain Research. 368: 87-100. PMID 2869820 DOI: 10.1016/0006-8993(86)91045-0  0.31
1984 Howe JR, Yaksh TL. [3H]p-Aminoclonidine binding to multiple alpha 2-adrenoceptor sites in homogenates of cat frontal cortex and cat spinal cord. European Journal of Pharmacology. 106: 547-59. PMID 6097461 DOI: 10.1016/0014-2999(84)90058-X  0.311
1983 Howe JR, Wang JY, Yaksh TL. Selective antagonism of the antinociceptive effect of intrathecally applied alpha adrenergic agonists by intrathecal prazosin and intrathecal yohimbine. The Journal of Pharmacology and Experimental Therapeutics. 224: 552-8. PMID 6131120  0.306
1982 Yaksh TL, Howe JR. Opiate receptors and their definition by antagonists. Anesthesiology. 56: 246-9. PMID 6278990 DOI: 10.1097/00000542-198204000-00002  0.475
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