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Cary H. Leung - Publications

Affiliations: 
Neurosurgery Emory University, Atlanta, GA 
 Widener University 
Area:
Gene Therapy, Behavioral Neuroendocrinolgy
Website:
http://www.science.widener.edu/~leung/
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Year Citation  Score
2016 Donsante A, McEachin Z, Riley J, Leung CH, Kanz L, O'Connor DM, Boulis NM. Intracerebroventricular delivery of self-complementary adeno-associated virus serotype 9 to the adult rat brain. Gene Therapy. PMID 26824881 DOI: 10.1038/Gt.2016.6  0.421
2011 Leung CH, Abebe DF, Earp SE, Goode CT, Grozhik AV, Mididoddi P, Maney DL. Neural distribution of vasotocin receptor mRNA in two species of songbird. Endocrinology. 152: 4865-81. PMID 22067316 DOI: 10.1210/en.2011-1394  0.523
2011 Leung CH, Kliem MA, Heeke BL, McPhee SW, Federici T, Snyder BR, Boulis NM. Assessment of hippocampal adeno-associated viral vector gene delivery via frameless stereotaxis in a nonhuman primate. Stereotactic and Functional Neurosurgery. 89: 275-85. PMID 21849811 DOI: 10.1159/000328265  0.415
2011 Snyder BR, Gray SJ, Quach ET, Huang JW, Leung CH, Samulski RJ, Boulis NM, Federici T. Comparison of adeno-associated viral vector serotypes for spinal cord and motor neuron gene delivery. Human Gene Therapy. 22: 1129-35. PMID 21443428 DOI: 10.1089/Hum.2011.008  0.404
2009 Leung CH, Goode CT, Young LJ, Maney DL. Neural distribution of nonapeptide binding sites in two species of songbird. The Journal of Comparative Neurology. 513: 197-208. PMID 19132730 DOI: 10.1002/cne.21947  0.526
2006 Adkins-Regan E, Leung CH. Sex steroids modulate changes in social and sexual preference during juvenile development in zebra finches. Hormones and Behavior. 50: 772-8. PMID 16919276 DOI: 10.1016/j.yhbeh.2006.07.003  0.484
2006 Adkins-Regan E, Leung CH. Hormonal and social modulation of cloacal muscle activity in female Japanese quail. Physiology & Behavior. 87: 82-7. PMID 16188285 DOI: 10.1016/j.physbeh.2005.08.047  0.485
Low-probability matches (unlikely to be authored by this person)
1996 Olofsson JI, Leung CH, Bjurulf E, Ohno T, Selstam G, Peng C, Leung PC. Characterization and regulation of a mRNA encoding the prostaglandin F2alpha receptor in the rat ovary. Molecular and Cellular Endocrinology. 123: 45-52. PMID 8912810  0.153
2023 Foster WB, Beach KF, Carson PF, Harris KC, Alonso BL, Costa LT, Simamora RC, Corbin JE, Hoag KF, Mercado SI, Bernhard AG, Leung CH, Nestler EJ, Been LE. Estradiol withdrawal following a hormone simulated pregnancy induces deficits in affective behaviors and increases ∆FosB in D1 and D2 neurons in the nucleus accumbens core in mice. Hormones and Behavior. 149: 105312. PMID 36645923 DOI: 10.1016/j.yhbeh.2023.105312  0.148
2018 Vellaisamy K, Li G, Ko CN, Zhong HJ, Fatima S, Kwan HY, Wong CY, Kwong WJ, Tan W, Leung CH, Ma DL. Cell imaging of dopamine receptor using agonist labeling iridium(iii) complex. Chemical Science. 9: 1119-1125. PMID 29675156 DOI: 10.1039/C7Sc04798C  0.146
2016 Liu LJ, Wang W, Kang TS, Liang JX, Liu C, Kwong DW, Wong VK, Ma DL, Leung CH. Antagonizing STAT5B dimerization with an osmium complex. Scientific Reports. 6: 36044. PMID 27853239 DOI: 10.1038/Srep36044  0.142
2014 Ma DL, Chan DS, Leung CH. Group 9 organometallic compounds for therapeutic and bioanalytical applications. Accounts of Chemical Research. 47: 3614-31. PMID 25369127 DOI: 10.1021/Ar500310Z  0.131
2018 Li PH, Liu LH, Chang CC, Gao R, Leung CH, Ma DL, David Wang HM. Silencing Stem Cell Factor Gene in Fibroblasts to Regulate Paracrine Factor Productions and Enhance c-Kit Expression in Melanocytes on Melanogenesis. International Journal of Molecular Sciences. 19. PMID 29772675 DOI: 10.3390/Ijms19051475  0.129
2015 Wang M, He B, Lu L, Leung CH, Mergny JL, Ma DL. Label-free luminescent detection of LMP1 gene deletion using an intermolecular G-quadruplex-based switch-on probe. Biosensors & Bioelectronics. 70: 338-44. PMID 25840020 DOI: 10.1016/J.Bios.2015.03.047  0.128
1999 Ottander U, Leung CH, Olofsson JI. Functional evidence for divergent receptor activation mechanisms of luteotrophic and luteolytic events in the human corpus luteum. Molecular Human Reproduction. 5: 391-5. PMID 10338360  0.128
2013 Yang H, Ma VP, Chan DS, He HZ, Leung CH, Ma DL. A cyclometallated iridium(III) complex as a c-myc G-quadruplex stabilizer and down-regulator of c-myc oncogene expression. Current Medicinal Chemistry. 20: 576-82. PMID 23116145 DOI: 10.2174/0929867311320040009  0.126
2018 Vellaisamy K, Li G, Wang W, Leung CH, Ma DL. A long-lived peptide-conjugated iridium(iii) complex as a luminescent probe and inhibitor of the cell migration mediator, formyl peptide receptor 2. Chemical Science. 9: 8171-8177. PMID 30568767 DOI: 10.1039/C8Sc02733A  0.126
2010 Wang P, Leung CH, Ma DL, Yan SC, Che CM. Structure-based design of platinum(II) complexes as c-myc oncogene down-regulators and luminescent probes for G-quadruplex DNA. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 6900-11. PMID 20437426 DOI: 10.1002/Chem.201000167  0.125
2012 Leung CH, Chan DS, He HZ, Cheng Z, Yang H, Ma DL. Luminescent detection of DNA-binding proteins. Nucleic Acids Research. 40: 941-55. PMID 21967849 DOI: 10.1093/Nar/Gkr763  0.124
2016 Lu L, Zhong HJ, He B, Leung CH, Ma DL. Development of a luminescent G-quadruplex-selective iridium(III) complex for the label-free detection of adenosine. Scientific Reports. 6: 19368. PMID 26778273 DOI: 10.1038/srep19368  0.124
2016 Wang M, Mao Z, Kang TS, Wong CY, Mergny JL, Leung CH, Ma DL. Conjugating a groove-binding motif to an Ir(iii) complex for the enhancement of G-quadruplex probe behavior Chemical Science. 7: 2516-2523. DOI: 10.1039/c6sc00001k  0.124
2010 Sun RW, Li CK, Ma DL, Yan JJ, Lok CN, Leung CH, Zhu N, Che CM. Stable anticancer gold(III)-porphyrin complexes: effects of porphyrin structure. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 3097-113. PMID 20162647 DOI: 10.1002/Chem.200902741  0.123
2020 Wang W, Wu KJ, Vellaisamy K, Leung CH, Ma DL. Peptide-conjugated long-lived theranostic imaging toolbox for targeting GRPr in cancer and immune cells. Angewandte Chemie (International Ed. in English). PMID 32649787 DOI: 10.1002/Anie.202007920  0.123
2012 Cornil CA, Leung CH, Pletcher ER, Naranjo KC, Blauman SJ, Saldanha CJ. Acute and specific modulation of presynaptic aromatization in the vertebrate brain. Endocrinology. 153: 2562-7. PMID 22508515 DOI: 10.1210/en.2011-2159  0.123
2013 Ma DL, He HZ, Leung KH, Zhong HJ, Chan DS, Leung CH. Label-free luminescent oligonucleotide-based probes. Chemical Society Reviews. 42: 3427-40. PMID 23348604 DOI: 10.1039/C2Cs35472A  0.122
2009 Wu P, Ma DL, Leung CH, Yan SC, Zhu N, Abagyan R, Che CM. Stabilization of G-quadruplex DNA with platinum(II) Schiff base complexes: luminescent probe and down-regulation of c-myc oncogene expression. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 13008-21. PMID 19876976 DOI: 10.1002/Chem.200901943  0.121
2016 Lin S, Lu L, Kang TS, Liu C, Mergny JL, Leung CH, Ma DL. The interaction of an iridium(III) complex with G-quadruplex DNA and its application in luminescent switch-on detection of Siglec-5. Analytical Chemistry. PMID 27678199 DOI: 10.1021/Acs.Analchem.6B03128  0.121
2016 Lu L, Wang W, Wang M, Kang TS, Lu JJ, Chen XP, Han QB, Leung CH, Ma DL. A luminescent G-quadruplex-selective iridium(iii) complex for the label-free detection of lysozyme Journal of Materials Chemistry B. 4: 2407-2411. DOI: 10.1039/c6tb00426a  0.117
2013 Leung KH, Lu L, Wang M, Mak TY, Chan DS, Tang FK, Leung CH, Kwan HY, Yu Z, Ma DL. A label-free luminescent switch-on assay for ATP using a G-quadruplex-selective iridium(III) complex. Plos One. 8: e77021. PMID 24204723 DOI: 10.1371/Journal.Pone.0077021  0.115
2013 Leung CH, He HZ, Liu LJ, Wang M, Chan DSH, Ma DL. Metal complexes as inhibitors of transcription factor activity Coordination Chemistry Reviews. 257: 3139-3151. DOI: 10.1016/J.Ccr.2013.08.008  0.114
2008 Yu K, Ganesan K, Tan LK, Laban M, Wu J, Zhao XD, Li H, Leung CH, Zhu Y, Wei CL, Hooi SC, Miller L, Tan P. A precisely regulated gene expression cassette potently modulates metastasis and survival in multiple solid cancers. Plos Genetics. 4: e1000129. PMID 18636107 DOI: 10.1371/journal.pgen.1000129  0.113
2015 Lu L, Wang M, Liu LJ, Leung CH, Ma DL. Label-Free Luminescent Switch-On Probe for Ochratoxin A Detection Using a G-Quadruplex-Selective Iridium(III) Complex. Acs Applied Materials & Interfaces. 7: 8313-8. PMID 25836665 DOI: 10.1021/Acsami.5B01702  0.112
2018 Leung CH, Yang GJ, Wang W, Mok SWF, Wu C, Law BYK, Miao XM, Wu KJ, Zhong HJ, Wong CY, Wong VKW, Ma DL. Selective inhibition of lysine-specific demethylase 5A (KDM5A) using a rhodium(III) complex for triple-negative breast cancer therapy. Angewandte Chemie (International Ed. in English). PMID 29968419 DOI: 10.1002/Anie.201807305  0.111
2011 Leung CH, Chan DS, Man BY, Wang CJ, Lam W, Cheng YC, Fong WF, Hsiao WL, Ma DL. Simple and convenient G-quadruplex-based turn-on fluorescence assay for 3' → 5' exonuclease activity. Analytical Chemistry. 83: 463-6. PMID 21114271 DOI: 10.1021/Ac1025896  0.111
2015 Zhong HJ, Lin S, Tam IL, Lu L, Chan DS, Ma DL, Leung CH. In silico identification of natural product inhibitors of JAK2. Methods (San Diego, Calif.). 71: 21-5. PMID 25038528 DOI: 10.1016/J.Ymeth.2014.07.003  0.111
2012 Ma DL, Chan DS, Fu WC, He HZ, Yang H, Yan SC, Leung CH. Discovery of a natural product-like c-myc G-quadruplex DNA groove-binder by molecular docking. Plos One. 7: e43278. PMID 22912844 DOI: 10.1371/Journal.Pone.0043278  0.109
2012 Ma DL, Ma VP, Chan DS, Leung KH, Zhong HJ, Leung CH. In silico screening of quadruplex-binding ligands. Methods (San Diego, Calif.). 57: 106-14. PMID 22391485 DOI: 10.1016/J.Ymeth.2012.02.001  0.109
2012 Zhong HJ, Yang H, Chan DS, Leung CH, Wang HM, Ma DL. A metal-based inhibitor of NEDD8-activating enzyme. Plos One. 7: e49574. PMID 23185368 DOI: 10.1371/Journal.Pone.0049574  0.109
2014 Lu L, Shiu-Hin Chan D, Kwong DWJ, He HZ, Leung CH, Ma DL. Detection of nicking endonuclease activity using a G-quadruplex-selective luminescent switch-on probe Chemical Science. 5: 4561-4568. DOI: 10.1039/C4Sc02032D  0.108
2015 Leung KH, He B, Yang C, Leung CH, Wang HM, Ma DL. Development of an Aptamer-based Sensing Platform for Metal Ions, Proteins and Small Molecules Through Terminal Deoxynucleotidyl Transferase-induced G-quadruplex Formation. Acs Applied Materials & Interfaces. PMID 26449329 DOI: 10.1021/acsami.5b08314  0.108
2011 Chan DS, Yang H, Kwan MH, Cheng Z, Lee P, Bai LP, Jiang ZH, Wong CY, Fong WF, Leung CH, Ma DL. Structure-based optimization of FDA-approved drug methylene blue as a c-myc G-quadruplex DNA stabilizer. Biochimie. 93: 1055-64. PMID 21377506 DOI: 10.1016/J.Biochi.2011.02.013  0.107
2003 Leung CH, Wilson DA. Trans-neuronal regulation of cortical apoptosis in the adult rat olfactory system. Brain Research. 984: 182-8. PMID 12932852 DOI: 10.1016/S0006-8993(03)03129-9  0.107
2013 Leung CH, Chan DS, Ma VP, Ma DL. DNA-binding small molecules as inhibitors of transcription factors. Medicinal Research Reviews. 33: 823-46. PMID 22549740 DOI: 10.1002/Med.21266  0.107
2016 Lu L, Wang W, Yang C, Kang TS, Leung CH, Ma DL. Iridium(iii) complexes with 1,10-phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection. Journal of Materials Chemistry. B. 4: 6791-6796. PMID 32263573 DOI: 10.1039/C6Tb02316A  0.107
2017 Ma DL, Leung CH. The development of G-quadruplex-based assays for the detection of small molecules and toxic substances. Chemistry, An Asian Journal. PMID 28470784 DOI: 10.1002/Asia.201700533  0.107
2016 Zhong HJ, Wang W, Kang TS, Yan H, Yang Y, Xu L, Wang Y, Ma DL, Leung CH. A Rhodium(III) Complex as an Inhibitor of Neural Precursor Cell Expressed, Developmentally Down-Regulated 8-Activating Enzyme with In Vivo Activity against Inflammatory Bowel Disease. Journal of Medicinal Chemistry. PMID 27976900 DOI: 10.1021/Acs.Jmedchem.6B00250  0.107
2015 Liu LJ, Lu L, Zhong HJ, He B, Kwong DW, Ma DL, Leung CH. An Iridium(III) Complex Inhibits JMJD2 Activities and Acts as A Potential Epigenetic Modulator. Journal of Medicinal Chemistry. PMID 26225543 DOI: 10.1021/Acs.Jmedchem.5B00375  0.106
2011 Wang P, Leung CH, Ma DL, Sun RW, Yan SC, Chen QS, Che CM. Specific blocking of CREB/DNA binding by cyclometalated platinum(II) complexes. Angewandte Chemie (International Ed. in English). 50: 2554-8. PMID 21370336 DOI: 10.1002/Anie.201006887  0.105
2015 Lu L, Liu LJ, Chao WC, Zhong HJ, Wang M, Chen XP, Lu JJ, Li RN, Ma DL, Leung CH. Identification of an iridium(III) complex with anti-bacterial and anti-cancer activity. Scientific Reports. 5: 14544. PMID 26416333 DOI: 10.1038/Srep14544  0.105
2018 Ma DL, Wu C, Tang W, Gupta AR, Lee FW, Li G, Leung CH. Recent advances in iridium(iii) complex-assisted nanomaterials for biological applications. Journal of Materials Chemistry. B. 6: 537-544. PMID 32254482 DOI: 10.1039/C7Tb02859H  0.105
2016 Lu L, Mao Z, Kang TS, Leung CH, Ma DL. A versatile nanomachine for the sensitive detection of platelet-derived growth factor-BB utilizing a G-quadruplex-selective iridium(III) complex. Biosensors & Bioelectronics. 85: 300-309. PMID 27183280 DOI: 10.1016/j.bios.2016.05.026  0.104
2011 Ma DL, Xu T, Chan DS, Man BY, Fong WF, Leung CH. A highly selective, label-free, homogenous luminescent switch-on probe for the detection of nanomolar transcription factor NF-kappaB. Nucleic Acids Research. 39: e67. PMID 21398636 DOI: 10.1093/Nar/Gkr106  0.104
2016 Liu JB, Liu LJ, Dong ZZ, Yang GJ, Leung CH, Ma DL. An Aldol Reaction-Based Iridium(III) Chemosensor for the Visualization of Proline in Living Cells. Scientific Reports. 6: 36509. PMID 27812033 DOI: 10.1038/Srep36509  0.104
2015 Ma DL, Lu L, Lin S, He B, Leung CH. A G-triplex luminescent switch-on probe for the detection of mung bean nuclease activity Journal of Materials Chemistry B. 3: 348-352. DOI: 10.1039/C4Tb01569J  0.103
2013 He HZ, Chan WI, Mak TY, Liu LJ, Wang M, Chan DS, Ma DL, Leung CH. Detection of 3'→5' exonuclease activity using a metal-based luminescent switch-on probe. Methods (San Diego, Calif.). 64: 218-23. PMID 23973810 DOI: 10.1016/J.Ymeth.2013.08.011  0.103
2013 Leung KH, He HZ, Wang W, Zhong HJ, Chan DS, Leung CH, Ma DL. Label-free luminescent switch-on detection of endonuclease IV activity using a G-quadruplex-selective iridium(III) complex. Acs Applied Materials & Interfaces. 5: 12249-53. PMID 24245499 DOI: 10.1021/Am404314P  0.101
2012 He HZ, Chan DS, Leung CH, Ma DL. A highly selective G-quadruplex-based luminescent switch-on probe for the detection of gene deletion. Chemical Communications (Cambridge, England). 48: 9462-4. PMID 22692458 DOI: 10.1039/C2Cc32253F  0.101
2012 Zhong HJ, Ma VP, Cheng Z, Chan DS, He HZ, Leung KH, Ma DL, Leung CH. Discovery of a natural product inhibitor targeting protein neddylation by structure-based virtual screening. Biochimie. 94: 2457-60. PMID 22709868 DOI: 10.1016/J.Biochi.2012.06.004  0.101
2014 Liu LJ, Lin S, Chan DS, Vong CT, Hoi PM, Wong CY, Ma DL, Leung CH. A rhodium(III) complex inhibits LPS-induced nitric oxide production and angiogenic activity in cellulo. Journal of Inorganic Biochemistry. 140: 23-8. PMID 25046384 DOI: 10.1016/J.Jinorgbio.2014.06.020  0.101
2004 Larrabee JA, Leung CH, Moore RL, Thamrong-nawasawat T, Wessler BS. Magnetic circular dichroism and cobalt(II) binding equilibrium studies of Escherichia coli methionyl aminopeptidase. Journal of the American Chemical Society. 126: 12316-24. PMID 15453765 DOI: 10.1021/ja0485006  0.1
2015 Leung KH, Liu LJ, Lin S, Lu L, Zhong HJ, Susanti D, Rao W, Wang M, Che WI, Chan DS, Leung CH, Chan PW, Ma DL. Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening. Methods (San Diego, Calif.). 71: 38-43. PMID 25160651 DOI: 10.1016/J.Ymeth.2014.07.010  0.099
2016 Lu L, Wang M, Mao Z, Kang TS, Chen XP, Lu JJ, Leung CH, Ma DL. A novel dinuclear iridium(III) complex as a G-quadruplex-selective probe for the luminescent switch-on detection of transcription factor HIF-1α. Scientific Reports. 6: 22458. PMID 26932240 DOI: 10.1038/Srep22458  0.099
2013 Leung C, Zhong H, Chan DS, Ma D. Bioactive iridium and rhodium complexes as therapeutic agents Coordination Chemistry Reviews. 257: 1764-1776. DOI: 10.1016/J.Ccr.2013.01.034  0.099
2013 Ma DL, He HZ, Leung KH, Chan DS, Leung CH. Bioactive luminescent transition-metal complexes for biomedical applications. Angewandte Chemie (International Ed. in English). 52: 7666-82. PMID 23765907 DOI: 10.1002/Anie.201208414  0.098
2017 Dong Z, Lu L, Wang W, Li G, Kang T, Han Q, Leung C, Ma D. Luminescent detection of nicking endonuclease Nb.BsmI activity by using a G-quadruplex-selective iridium(III) complex in aqueous solution Sensors and Actuators B: Chemical. 246: 826-832. DOI: 10.1016/J.Snb.2017.02.156  0.098
2017 Wang W, Dong Z, Yang C, Li G, Tse Y, Leung C, Ma D. An iridium(III) complex-based chemosensor for the detection of thiourea in living cells Sensors and Actuators B: Chemical. 251: 374-379. DOI: 10.1016/J.Snb.2017.05.100  0.098
2013 Leung KH, He HZ, Zhong HJ, Lu L, Chan DS, Ma DL, Leung CH. A highly sensitive G-quadruplex-based luminescent switch-on probe for the detection of polymerase 3'-5' proofreading activity. Methods (San Diego, Calif.). 64: 224-8. PMID 23748144 DOI: 10.1016/J.Ymeth.2013.05.017  0.098
2018 Kang TS, Ko CN, Zhang JT, Wu C, Wong CY, Ma DL, Leung CH. Rhodium(III)-Based Inhibitor of the JMJD3-H3K27me3 Interaction and Modulator of the Inflammatory Response. Inorganic Chemistry. PMID 30375229 DOI: 10.1021/Acs.Inorgchem.8B02256  0.097
2008 Park SY, Leung CH, Cheng YC. ATP modulates poly(ADP-ribose) polymerase-1-facilitated topoisomerase I-linked DNA religation in the presence of camptothecin. Molecular Pharmacology. 73: 1829-37. PMID 18349103 DOI: 10.1124/mol.107.044438  0.097
2014 Ma DL, He HZ, Chan DS, Wong CY, Leung CH. A colorimetric and luminescent dual-modal assay for Cu(II) ion detection using an iridium(III) complex. Plos One. 9: e99930. PMID 24927177 DOI: 10.1371/Journal.Pone.0099930  0.097
2014 Wong CY, Chung LH, Lin S, Chan DS, Leung CH, Ma DL. A ruthenium(II) complex supported by trithiacyclononane and aromatic diimine ligand as luminescent switch-on probe for biomolecule detection and protein staining. Scientific Reports. 4: 7136. PMID 25409703 DOI: 10.1038/srep07136  0.097
2015 Zhong HJ, Leung KH, Lin S, Chan DS, Han QB, Chan SL, Ma DL, Leung CH. Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme. Methods (San Diego, Calif.). 71: 71-6. PMID 25196325 DOI: 10.1016/j.ymeth.2014.08.014  0.097
2015 Lin X, Leung KH, Lin L, Lin L, Lin S, Leung CH, Ma DL, Lin JM. Determination of cell metabolite VEGF165 and dynamic analysis of protein-DNA interactions by combination of microfluidic technique and luminescent switch-on probe. Biosensors & Bioelectronics. 79: 41-47. PMID 26686922 DOI: 10.1016/j.bios.2015.11.089  0.096
2013 Leung KH, He HZ, Chan DSH, Fu WC, Leung CH, Ma DL. An oligonucleotide-based switch-on luminescent probe for the detection of kanamycin in aqueous solution Sensors and Actuators, B: Chemical. 177: 487-492. DOI: 10.1016/J.Snb.2012.11.053  0.096
2015 Wang M, Wang W, Kang TS, Leung CH, Ma DL. Development of an iridium(III) complex as a G-quadruplex probe and its application for the G-quadruplex-based luminescent detection of picomolar insulin. Analytical Chemistry. PMID 26607385 DOI: 10.1021/Acs.Analchem.5B04064  0.095
2017 Liu J, Yang C, Ko C, Vellaisamy K, Yang B, Lee M, Leung C, Ma D. A long lifetime iridium(III) complex as a sensitive luminescent probe for bisulfite detection in living zebrafish Sensors and Actuators B: Chemical. 243: 971-976. DOI: 10.1016/J.Snb.2016.12.083  0.095
2014 Ma DL, Lin S, Leung KH, Zhong HJ, Liu LJ, Chan DS, Bourdoncle A, Mergny JL, Wang HM, Leung CH. An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(III) complex. Nanoscale. 6: 8489-94. PMID 24816304 DOI: 10.1039/C4Nr00541D  0.095
2015 Lin S, He B, Yang C, Leung CH, Mergny JL, Ma DL. Luminescence switch-on assay of interferon-gamma using a G-quadruplex-selective iridium(iii) complex. Chemical Communications (Cambridge, England). PMID 26399215 DOI: 10.1039/c5cc06655g  0.095
2017 Ma DL, Lin S, Wang W, Yang C, Leung CH. Luminescent chemosensors by using cyclometalated iridium(iii) complexes and their applications. Chemical Science. 8: 878-889. PMID 28572899 DOI: 10.1039/C6Sc04175B  0.095
2013 Leung CH, Zhong HJ, Lu L, Chan DS, Ma DL. Luminescent and colorimetric strategies for the label-free DNA-based detection of enzyme activity. Briefings in Functional Genomics. 12: 525-35. PMID 23396725 DOI: 10.1093/bfgp/elt004  0.095
2014 He HZ, Leung KH, Wang W, Chan DS, Leung CH, Ma DL. Label-free luminescence switch-on detection of T4 polynucleotide kinase activity using a G-quadruplex-selective probe. Chemical Communications (Cambridge, England). 50: 5313-5. PMID 24336506 DOI: 10.1039/C3Cc47444E  0.095
2014 Ma DL, He HZ, Zhong HJ, Lin S, Chan DS, Wang L, Lee SM, Leung CH, Wong CY. Visualization of Zn²⁺ ions in live zebrafish using a luminescent iridium(III) chemosensor. Acs Applied Materials & Interfaces. 6: 14008-15. PMID 25051997 DOI: 10.1021/Am504369B  0.094
2018 Liu JB, Vellaisamy K, Li G, Yang C, Wong SY, Leung CH, Pu SZ, Ma DL. A long-lifetime iridium(iii) complex for lysosome tracking with high specificity and a large Stokes shift. Journal of Materials Chemistry. B. 6: 3855-3858. PMID 32254312 DOI: 10.1039/C8Tb00666K  0.094
2015 Susanti D, Liu LJ, Rao W, Lin S, Ma DL, Leung CH, Chan PW. Gold-Catalyzed Cycloisomerization and Diels-Alder Reaction of 1,4,9-Dienyne Esters to 3 a,6-Methanoisoindole Esters with Pro-Inflammatory Cytokine Antagonist Activity. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 9111-8. PMID 25982956 DOI: 10.1002/chem.201500795  0.094
2015 Ma DL, Wang M, Lin S, Han QB, Leung CH. Recent Development of G-Quadruplex Probes for Cellular Imaging. Current Topics in Medicinal Chemistry. 15: 1957-63. PMID 25980414 DOI: 10.2174/1568026615666150515150106  0.094
2016 Ma DL, Wang M, Mao Z, Yang C, Ng CT, Leung CH. Rhodium complexes as therapeutic agents. Dalton Transactions (Cambridge, England : 2003). PMID 26743935 DOI: 10.1039/C5Dt04338G  0.093
2017 Yang C, Wang W, Liang J, Li G, Vellaisamy K, Wong CY, Ma DL, Leung CH. A rhodium(III)-based inhibitor of lysine-specific histone demethylase 1 as an epigenetic modulator in prostate cancer cells. Journal of Medicinal Chemistry. PMID 28219005 DOI: 10.1021/Acs.Jmedchem.7B00133  0.093
2011 Ma DL, Chan DS, Lee P, Kwan MH, Leung CH. Molecular modeling of drug-DNA interactions: virtual screening to structure-based design. Biochimie. 93: 1252-66. PMID 21514356 DOI: 10.1016/J.Biochi.2011.04.002  0.093
2001 Ng HK, Leung CH, Boet R, Poon WS. Spinal cord pilocytic astrocytoma with cranial meningeal metastases. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 8: 374-7. PMID 11437586 DOI: 10.1054/jocn.2000.0762  0.093
2013 He HZ, Leung KH, Yang H, Chan DS, Leung CH, Zhou J, Bourdoncle A, Mergny JL, Ma DL. Label-free detection of sub-nanomolar lead(II) ions in aqueous solution using a metal-based luminescent switch-on probe. Biosensors & Bioelectronics. 41: 871-4. PMID 23040875 DOI: 10.1016/J.Bios.2012.08.060  0.093
2013 He HZ, Chan DS, Leung CH, Ma DL. G-quadruplexes for luminescent sensing and logic gates. Nucleic Acids Research. 41: 4345-59. PMID 23435319 DOI: 10.1093/Nar/Gkt108  0.092
2013 He HZ, Wang M, Chan DS, Leung CH, Qiu JW, Ma DL. A label-free G-quadruplex-based luminescent switch-on assay for the selective detection of histidine. Methods (San Diego, Calif.). 64: 205-11. PMID 23891801 DOI: 10.1016/J.Ymeth.2013.07.023  0.092
2015 Lin S, Yang C, Mao Z, He B, Wang YT, Leung CH, Ma DL. A G-pentaplex-based assay for Cs(+) ions in aqueous solution using a luminescent Ir(III) complex. Biosensors & Bioelectronics. 77: 609-612. PMID 26479906 DOI: 10.1016/j.bios.2015.10.026  0.092
2017 Wang W, Dong ZZ, Yang G, Leung CH, Lin S, Ma DL. A long-lived iridium(iii) chemosensor for the real-time detection of GHB. Journal of Materials Chemistry. B. 5: 2739-2742. PMID 32264159 DOI: 10.1039/C6Tb03396B  0.092
2019 Ma DL, Wong SY, Kang TS, Ng HP, Han QB, Leung CH. Iridium(III)-based chemosensors for the detection of metal ions. Methods (San Diego, Calif.). PMID 30797032 DOI: 10.1016/J.Ymeth.2019.02.013  0.092
2015 Lu L, Wang M, Liu LJ, Wong CY, Leung CH, Ma DL. A luminescence switch-on probe for terminal deoxynucleotidyl transferase (TdT) activity detection by using an iridium(iii)-based i-motif probe. Chemical Communications (Cambridge, England). 51: 9953-6. PMID 25999030 DOI: 10.1039/C5Cc02790J  0.092
2006 Leung CH, Grill SP, Lam W, Gao W, Sun HD, Cheng YC. Eriocalyxin B inhibits nuclear factor-kappaB activation by interfering with the binding of both p65 and p50 to the response element in a noncompetitive manner. Molecular Pharmacology. 70: 1946-55. PMID 16940413 DOI: 10.1124/mol.106.028480  0.091
2014 Ma DL, Liu LJ, Leung KH, Chen YT, Zhong HJ, Chan DS, Wang HM, Leung CH. Antagonizing STAT3 dimerization with a rhodium(III) complex. Angewandte Chemie (International Ed. in English). 53: 9178-82. PMID 24889897 DOI: 10.1002/Anie.201404686  0.091
2011 Qiu GH, Leung CH, Yun T, Xie X, Laban M, Hooi SC. Recognition and suppression of transfected plasmids by protein ZNF511-PRAP1, a potential molecular barrier to transgene expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1478-86. PMID 21540836 DOI: 10.1038/mt.2011.80  0.091
2013 Yang H, Zhong HJ, Leung KH, Chan DS, Ma VP, Fu WC, Nanjunda R, Wilson WD, Ma DL, Leung CH. Structure-based design of flavone derivatives as c-myc oncogene down-regulators. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 48: 130-41. PMID 23127826 DOI: 10.1016/J.Ejps.2012.10.010  0.09
2019 Liu JB, Wu C, Chen F, Leung CH, Ma DL. A simple iridium(III) dimer as a switch-on luminescent chemosensor for carbon disulfide detection in water samples. Analytica Chimica Acta. 1083: 166-171. PMID 31493807 DOI: 10.1016/J.Aca.2019.07.070  0.09
2017 Wang M, Wang W, Liu C, Liu J, Kang T, Leung C, Ma D. A luminescence switch-on assay for the detection of specific gene deletion using G-quadruplex DNA and silver nanoclusters Materials Chemistry Frontiers. 1: 128-131. DOI: 10.1039/C6Qm00068A  0.089
2014 Wang M, Leung KH, Lin S, Chan DSH, Leung CH, Ma DL. A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag+ions based on the exonuclease III-mediated digestion of C-Ag+-C DNA Journal of Materials Chemistry B. 20: 6467-6471. DOI: 10.1039/c4tb01140f  0.089
2020 Yang GJ, Wang W, Lei PM, Leung CH, Ma DL. A 7-methoxybicoumarin derivative selectively inhibits BRD4 BD2 for anti-melanoma therapy. International Journal of Biological Macromolecules. PMID 32860796 DOI: 10.1016/J.Ijbiomac.2020.08.194  0.089
2016 Miao X, Yang C, Leung CH, Ma DL. Application of iridium(III) complex in label-free and non-enzymatic electrochemical detection of hydrogen peroxide based on a novel "on-off-on" switch platform. Scientific Reports. 6: 25774. PMID 27170211 DOI: 10.1038/srep25774  0.088
2015 Ma DL, Lin S, Lu L, Wang M, Hu C, Liu LJ, Ren K, Leung CH. G-quadruplex-based logic gates for HgII and AgI ions employing a luminescent iridium(III) complex and extension of metal-mediated base pairs by polymerase Journal of Materials Chemistry B. 3: 4780-4785. DOI: 10.1039/c5tb00718f  0.088
2017 Liu J, Dong ZZ, Yang C, Li G, Wu C, Lee FW, Leung CH, Ma DL. Turn-on Luminescent Probe for Hydrogen Peroxide Sensing and Imaging in Living Cells based on an Iridium(III) Complex-Silver Nanoparticle Platform. Scientific Reports. 7: 8980. PMID 28827747 DOI: 10.1038/S41598-017-09478-6  0.088
2015 Hseu YC, Cheng KC, Lin YC, Chen CY, Chou HY, Ma DL, Leung CH, Wen ZH, Wang HD. Synergistic effects of linderanolide B combined with arbutin, PTU or kojic acid on tyrosinase inhibition. Current Pharmaceutical Biotechnology. PMID 26343134 DOI: 10.2174/1389201016666150907112819  0.088
2007 Ying C, Li Y, Leung CH, Robek MD, Cheng YC. Unique antiviral mechanism discovered in anti-hepatitis B virus research with a natural product analogue. Proceedings of the National Academy of Sciences of the United States of America. 104: 8526-31. PMID 17488817 DOI: 10.1073/Pnas.0609883104  0.088
2017 Liang JX, Zhong HJ, Yang G, Vellaisamy K, Ma DL, Leung CH. Recent development of transition metal complexes with in vivo antitumor activity. Journal of Inorganic Biochemistry. PMID 28641893 DOI: 10.1016/J.Jinorgbio.2017.06.002  0.088
2019 Wang W, Lu L, Wu K, Liu J, Leung C, Wong C, Ma D. Long-lived iridium(III) complexes as luminescent probes for the detection of periodate in living cells Sensors and Actuators B: Chemical. 288: 392-398. DOI: 10.1016/J.Snb.2019.03.019  0.088
2003 Wu JY, Fong WF, Zhang JX, Leung CH, Kwong HL, Yang MS, Li D, Cheung HY. Reversal of multidrug resistance in cancer cells by pyranocoumarins isolated from Radix Peucedani. European Journal of Pharmacology. 473: 9-17. PMID 12877932 DOI: 10.1016/S0014-2999(03)01946-0  0.088
2016 Lin S, Kang TS, Lu L, Wang W, Ma DL, Leung CH. A G-quadruplex-selective luminescent probe with an anchor tail for the switch-on detection of thymine DNA glycosylase activity. Biosensors & Bioelectronics. 86: 849-857. PMID 27494808 DOI: 10.1016/J.Bios.2016.07.082  0.087
1999 Bekkaoui F, McNevin JP, Leung CH, Peterson GJ, Patel A, Bhatt RS, Bryan RN. Rapid detection of the mecA gene in methicillin resistant staphylococci using a colorimetric cycling probe technology. Diagnostic Microbiology and Infectious Disease. 34: 83-90. PMID 10354856 DOI: 10.1016/S0732-8893(99)00012-7  0.087
2018 Wu C, Wu KJ, Kang TS, Wang HD, Leung CH, Liu JB, Ma DL. Iridium-based probe for luminescent nitric oxide monitoring in live cells. Scientific Reports. 8: 12467. PMID 30127525 DOI: 10.1038/S41598-018-30991-9  0.087
2017 Ma DL, Dong ZZ, Vellaisamy K, Cheung KM, Yang G, Leung CH. Luminescent Strategies for Label-free G-quadruplex-based Enzyme Activity Sensing. Chemical Record (New York, N.Y.). PMID 28467681 DOI: 10.1002/Tcr.201700014  0.087
2010 Wang P, Leung CH, Ma DL, Lu W, Che CM. Organoplatinum(II) complexes with nucleobase motifs as inhibitors of human topoisomerase II catalytic activity. Chemistry, An Asian Journal. 5: 2271-80. PMID 20730852 DOI: 10.1002/Asia.201000451  0.086
2018 Ma DL, Ng HP, Wong SY, Vellaisamy K, Wu KJ, Leung CH. Iridium(iii) complexes as reaction based chemosensors for medical diagnostics. Dalton Transactions (Cambridge, England : 2003). PMID 30270395 DOI: 10.1039/C8Dt03492C  0.086
2016 Lin S, Lu L, Liu JB, Liu C, Kang TS, Yang C, Leung CH, Ma DL. A G-quadruplex-selective luminescent iridium(III) complex and its application by long lifetime. Biochimica Et Biophysica Acta. PMID 27592730 DOI: 10.1016/J.Bbagen.2016.08.022  0.086
2013 Leung KH, He HZ, Ma VP, Zhong HJ, Chan DS, Zhou J, Mergny JL, Leung CH, Ma DL. Detection of base excision repair enzyme activity using a luminescent G-quadruplex selective switch-on probe. Chemical Communications (Cambridge, England). 49: 5630-2. PMID 23559154 DOI: 10.1039/C3Cc41129J  0.085
2015 Tsui WK, Chung LH, Wong MM, Tsang WH, Lo HS, Liu Y, Leung CH, Ma DL, Chiu SK, Wong CY. Luminescent ruthenium(II) complex bearing bipyridine and N-heterocyclic carbene-based C∧N∧C pincer ligand for live-cell imaging of endocytosis. Scientific Reports. 5: 9070. PMID 25765974 DOI: 10.1038/Srep09070  0.085
2014 Liu LJ, Leung KH, Chan DS, Wang YT, Ma DL, Leung CH. Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual screening. Cell Death & Disease. 5: e1293. PMID 24922077 DOI: 10.1038/cddis.2014.250  0.085
2020 Ma DL, Wu C, Li G, Yung TL, Leung CH. Transition metal complexes as imaging or therapeutic agents for neurodegenerative diseases. Journal of Materials Chemistry. B. PMID 32100789 DOI: 10.1039/C9Tb02669J  0.085
2011 Liu J, Leung CH, Chow AL, Sun RW, Yan SC, Che CM. Cyclometalated platinum(II) complexes as topoisomerase IIα poisons. Chemical Communications (Cambridge, England). 47: 719-21. PMID 21072335 DOI: 10.1039/C0Cc03641B  0.085
2005 Leung CH, Grill SP, Lam W, Han QB, Sun HD, Cheng YC. Novel mechanism of inhibition of nuclear factor-kappa B DNA-binding activity by diterpenoids isolated from Isodon rubescens. Molecular Pharmacology. 68: 286-97. PMID 15872117 DOI: 10.1124/mol.105.012765  0.085
2016 Liu LJ, Wang W, Zhong Z, Lin S, Lu L, Wang YT, Ma DL, Leung CH. Inhibition of TLR1/2 dimerization by enantiomers of metal complexes. Chemical Communications (Cambridge, England). PMID 27711294 DOI: 10.1039/C6Cc06155A  0.085
2017 Ko CN, Yang C, Lin S, Li S, Dong Z, Liu J, Lee SM, Leung CH, Ma DL. A long-lived phosphorescence iridium(III) complex as a switch on-off-on probe for live zebrafish monitoring of endogenous sulfide generation. Biosensors & Bioelectronics. 94: 575-583. PMID 28364704 DOI: 10.1016/J.Bios.2017.03.050  0.084
2012 He HZ, Ma VP, Leung KH, Chan DS, Yang H, Cheng Z, Leung CH, Ma DL. A label-free G-quadruplex-based switch-on fluorescence assay for the selective detection of ATP. The Analyst. 137: 1538-40. PMID 22343772 DOI: 10.1039/C2An15999F  0.084
2015 Ma DL, Wang M, He B, Yang C, Wang W, Leung CH. A luminescent cocaine detection platform using a split G-quadruplex-selective iridium(III) complex and a three-way DNA junction architecture. Acs Applied Materials & Interfaces. PMID 26284502 DOI: 10.1021/Acsami.5B05861  0.084
2019 Ma DL, Wu C, Cheng SS, Lee FW, Han QB, Leung CH. Development of Natural Product-Conjugated Metal Complexes as Cancer Therapies. International Journal of Molecular Sciences. 20. PMID 30650627 DOI: 10.3390/Ijms20020341  0.084
2015 Wong CY, Chung LH, Lu L, Wang M, He B, Liu LJ, Leung CH, Ma DL. Dual Inhibition and Monitoring of Beta-Amyloid Fibrillation by a Luminescent Iridium(III) Complex. Current Alzheimer Research. 12: 439-44. PMID 25938873 DOI: 10.2174/1567205012666150504144558  0.083
2016 Tian Y, Zhang L, Shen J, Wu L, He H, Ma DL, Leung CH, Wu W, Fan Q, Huang W, Wang L. An Individual Nanocube-Based Plasmonic Biosensor for Real-Time Monitoring the Structural Switch of the Telomeric G-Quadruplex. Small (Weinheim An Der Bergstrasse, Germany). PMID 27106517 DOI: 10.1002/Smll.201600041  0.083
2018 Wang W, Wu C, Yang C, Li G, Han Q, Li S, Lee SM, Leung C, Ma D. A dual-functional luminescent probe for imaging H2S in living zebrafish and discrimination hypoxic cells from normoxic cells Sensors and Actuators B: Chemical. 255: 1953-1959. DOI: 10.1016/J.Snb.2017.08.222  0.083
2014 Lu L, He HZ, Zhong HJ, Liu LJ, Chan DSH, Leung CH, Ma DL. Luminescent detection of human serum albumin in aqueous solution using a cyclometallated iridium(III) complex Sensors and Actuators, B: Chemical. 201: 177-184. DOI: 10.1016/J.Snb.2014.04.100  0.083
2014 Leung CH, Wang L, Nielsen JM, Tropak MB, Fu YY, Kato H, Callahan J, Redington AN, Caldarone CA. Remote cardioprotection by transfer of coronary effluent from ischemic preconditioned rabbit heart preserves mitochondrial integrity and function via adenosine receptor activation. Cardiovascular Drugs and Therapy / Sponsored by the International Society of Cardiovascular Pharmacotherapy. 28: 7-17. PMID 24018748 DOI: 10.1007/s10557-013-6489-2  0.083
2015 Leung KH, He HZ, He B, Zhong HJ, Lin S, Wang YT, Ma DL, Leung CH. Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe Chemical Science. 6: 2166-2171. DOI: 10.1039/c4sc03319a  0.082
2010 Lee HM, Chan DS, Yang F, Lam HY, Yan SC, Che CM, Ma DL, Leung CH. Identification of natural product fonsecin B as a stabilizing ligand of c-myc G-quadruplex DNA by high-throughput virtual screening. Chemical Communications (Cambridge, England). 46: 4680-2. PMID 20383387 DOI: 10.1039/B926359D  0.081
2017 Lin S, Wang W, Hu C, Yang G, Ko CN, Ren K, Leung CH, Ma DL. The application of a G-quadruplex based assay with an iridium(iii) complex to arsenic ion detection and its utilization in a microfluidic chip. Journal of Materials Chemistry. B. 5: 479-484. PMID 32263664 DOI: 10.1039/C6Tb02656G  0.081
2016 Ma DL, Wang M, Liu C, Miao X, Kang TS, Leung CH. Metal complexes for the detection of disease-related protein biomarkers Coordination Chemistry Reviews. 324: 90-105. DOI: 10.1016/J.Ccr.2016.07.010  0.081
2014 Chung LH, Yeung CF, Ma DL, Leung CH, Wong CY. Metal-indolizine zwitterion complexes as a new class of organometallic material: A spectroscopic and theoretical investigation Organometallics. 33: 3443-3452. DOI: 10.1021/Om5003705  0.081
2015 Ma DL, Liu LJ, Lin S, Wang M, Chan DSH, Leung CH. Recent Advances in the Discovery and Development of Protein-Protein Interaction Modulators by Virtual Screening Frontiers in Computational Chemistry. 1: 121-157. DOI: 10.1016/B978-1-60805-865-5.50004-6  0.08
2019 Ma DL, Wu C, Wu KJ, Leung CH. Iridium(III) Complexes Targeting Apoptotic Cell Death in Cancer Cells. Molecules (Basel, Switzerland). 24. PMID 31357712 DOI: 10.3390/Molecules24152739  0.08
2019 Zhang JT, Kang TS, Wong SY, Pei RJ, Ma DL, Leung CH. An iridium(III) complex/G-quadruplex ensemble for detection of ochratoxin A based on long-lifetime luminescent. Analytical Biochemistry. PMID 31194944 DOI: 10.1016/J.Ab.2019.06.005  0.079
2014 Zhong HJ, Liu LJ, Chan DS, Wang HM, Chan PW, Ma DL, Leung CH. Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme. Biochimie. 102: 211-5. PMID 24657219 DOI: 10.1016/j.biochi.2014.03.005  0.079
2017 Wu C, Vellaisamy K, Yang G, Dong ZZ, Leung CH, Liu JB, Ma DL. A reaction-based luminescent switch-on sensor for the detection of OH(-) ions in simulated wastewater. Dalton Transactions (Cambridge, England : 2003). PMID 28484771 DOI: 10.1039/C7Dt00633K  0.079
2014 Lin S, He B, Shiu-Hin Chan D, Hong Chan PW, Leung CH, Ma DL. A G-quadruplex-based platform for the detection of Hg2+ ions using a luminescent iridium(iii) complex Rsc Advances. 4: 54826-54831. DOI: 10.1039/c4ra11240g  0.079
2016 Mao Z, Wang M, Liu J, Liu LJ, Lee SM, Leung CH, Ma DL. A long lifetime switch-on iridium(iii) chemosensor for the visualization of cysteine in live zebrafish. Chemical Communications (Cambridge, England). PMID 26899271 DOI: 10.1039/C6Cc01008C  0.079
2018 Wu C, Liu J, Li G, Wong S, Han Q, Leung C, Ma D. Chemoselective detection of alkyl halides via an iridium(III) luminescent probe Dyes and Pigments. 159: 479-482. DOI: 10.1016/J.Dyepig.2018.07.029  0.078
2005 Choi S, Cooley RB, Voutchkova A, Leung CH, Vastag L, Knowles DE. Oxidation of guanosine derivatives by a platinum(IV) complex: internal electron transfer through cyclization. Journal of the American Chemical Society. 127: 1773-81. PMID 15701012 DOI: 10.1021/Ja045194N  0.078
2017 Dong ZZ, Yang C, Vellaisamy K, Li G, Leung CH, Ma DL. Construction of a nano biosensor for cyanide anion detection and its application in environmental and biological systems. Acs Sensors. PMID 28948760 DOI: 10.1021/Acssensors.7B00553  0.078
2016 Xu SW, Law BY, Mok SW, Leung EL, Fan XX, Coghi PS, Zeng W, Leung CH, Ma DL, Liu L, Wong VK. Autophagic degradation of epidermal growth factor receptor in gefitinib-resistant lung cancer by celastrol. International Journal of Oncology. PMID 27498688 DOI: 10.3892/Ijo.2016.3644  0.078
2014 Zhong HJ, Leung KH, Liu LJ, Lu L, Chan DSH, Leung CH, Ma DL. Antagonism of mTOR activity by a kinetically inert rhodium(III) complex Chempluschem. 79: 508-511. DOI: 10.1002/cplu.201400014  0.077
2013 Ma DL, Zhong HJ, Fu WC, Chan DS, Kwan HY, Fong WF, Chung LH, Wong CY, Leung CH. Phosphorescent imaging of living cells using a cyclometalated iridium (III) complex. Plos One. 8: e55751. PMID 23457478 DOI: 10.1371/Journal.Pone.0055751  0.077
2017 Wang W, Yang C, Lin S, Vellaisamy K, Li G, Tan W, Leung CH, Ma DL. First Synthesis of an Oridonin-Conjugated Iridium(III) Complex for the Intracellular Tracking of NF-κB in Living Cells. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28211965 DOI: 10.1002/Chem.201700770  0.077
2012 Ma DL, He HZ, Ma VP, Chan DS, Leung KH, Zhong HJ, Lu L, Mergny JL, Leung CH. Label-free sensing of pH and silver nanoparticles using an "OR" logic gate. Analytica Chimica Acta. 733: 78-83. PMID 22704379 DOI: 10.1016/J.Aca.2012.04.041  0.077
2017 Yang C, Wang W, Li GD, Zhong HJ, Dong ZZ, Wong CY, Kwong DW, Ma DL, Leung CH. Anticancer osmium complex inhibitors of the HIF-1α and p300 protein-protein interaction. Scientific Reports. 7: 42860. PMID 28225008 DOI: 10.1038/Srep42860  0.077
2013 Leung KH, He HZ, Ma VPY, Yang H, Chan DSH, Leung CH, Ma DL. A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase Rsc Advances. 3: 1656-1659. DOI: 10.1039/C2Ra21996D  0.076
2017 Ko CN, Wu C, Li G, Leung CH, Liu JB, Ma DL. A long-lived ferrocene-conjugated iridium(III) complex for sensitive turn-on luminescence detection of traces of DMSO in water and human serum. Analytica Chimica Acta. 984: 193-201. PMID 28843564 DOI: 10.1016/J.Aca.2017.06.042  0.076
2012 Leung CH, Zhong HJ, Yang H, Cheng Z, Chan DS, Ma VP, Abagyan R, Wong CY, Ma DL. A metal-based inhibitor of tumor necrosis factor-α. Angewandte Chemie (International Ed. in English). 51: 9010-4. PMID 22807261 DOI: 10.1002/Anie.201202937  0.076
2013 He HZ, Wang M, Chan DS, Leung CH, Lin X, Lin JM, Ma DL. A parallel G-quadruplex-selective luminescent probe for the detection of nanomolar calcium(II) ion. Methods (San Diego, Calif.). 64: 212-7. PMID 23876936 DOI: 10.1016/J.Ymeth.2013.07.021  0.076
2015 Lu L, Zhong HJ, Wang M, Ho SL, Li HW, Leung CH, Ma DL. Inhibition of Beta-Amyloid Fibrillation by Luminescent Iridium(III) Complex Probes. Scientific Reports. 5: 14619. PMID 26419607 DOI: 10.1038/Srep14619  0.076
2011 Man BYW, Chan HM, Leung CH, Chan DSH, Bai LP, Jiang ZH, Li HW, Ma DL. Group 9 metal-based inhibitors of β-amyloid (1-40) fibrillation as potential therapeutic agents for Alzheimer's disease Chemical Science. 2: 917-921. DOI: 10.1039/C0Sc00636J  0.075
2017 Wu KJ, Zhong HJ, Li G, Liu C, Wang HD, Ma DL, Leung CH. Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing. European Journal of Medicinal Chemistry. 143: 1021-1027. PMID 29232579 DOI: 10.1016/J.Ejmech.2017.11.101  0.075
2016 Kang TS, Mao Z, Ng CT, Wang M, Wang W, Wang C, Lee SM, Wang Y, Leung CH, Ma DL. Identification of an Iridium(III)-Based Inhibitor of Tumor Necrosis Factor-α. Journal of Medicinal Chemistry. PMID 27054262 DOI: 10.1021/Acs.Jmedchem.6B00112  0.075
2020 Cheng SS, Yang GJ, Wang W, Leung CH, Ma DL. The design and development of covalent protein-protein interaction inhibitors for cancer treatment. Journal of Hematology & Oncology. 13: 26. PMID 32228680 DOI: 10.1186/S13045-020-00850-0  0.075
2019 Ko CN, Sun H, Wu KJ, Leung CH, Ren K, Ma DL. A portable oligonucleotide-based microfluidic device for the detection of VEGF in a three-step suspended-droplet mode. Dalton Transactions (Cambridge, England : 2003). PMID 31147654 DOI: 10.1039/C9Dt00427K  0.075
2017 Kang TS, Wang W, Zhong HJ, Dong ZZ, Huang Q, Fai Mok SW, Leung CH, Wai Wong VK, Ma DL. An anti-prostate cancer benzofuran-conjugated iridium(III) complex as a dual inhibitor of STAT3 and NF-κB. Cancer Letters. PMID 28323031 DOI: 10.1016/J.Canlet.2017.03.016  0.075
2009 Leung CH, Lam W, Ma DL, Gullen EA, Cheng YC. Butyrate mediates nucleotide-binding and oligomerisation domain (NOD) 2-dependent mucosal immune responses against peptidoglycan. European Journal of Immunology. 39: 3529-37. PMID 19830732 DOI: 10.1002/Eji.200939454  0.075
2015 Ma DL, Zhang Z, Wang M, Lu L, Zhong HJ, Leung CH. Recent Developments in G-Quadruplex Probes. Chemistry & Biology. 22: 812-28. PMID 26190823 DOI: 10.1016/J.Chembiol.2015.06.016  0.075
2012 Huang BH, Zhuo JL, Leung CH, Lu GD, Liu JJ, Yap CT, Hooi SC. PRAP1 is a novel executor of p53-dependent mechanisms in cell survival after DNA damage. Cell Death & Disease. 3: e442. PMID 23235459 DOI: 10.1038/cddis.2012.180  0.074
2000 Lam W, Leung CH, Chan HL, Fong WF. Toxicity and DNA binding of dextran-doxorubicin conjugates in multidrug-resistant KB-V1 cells: optimization of dextran size. Anti-Cancer Drugs. 11: 377-84. PMID 10912954  0.074
2013 Chan DS, Fu WC, Wang M, Liu LJ, Leung CH, Ma DL. A highly selective and non-reaction based chemosensor for the detection of Hg2+ ions using a luminescent iridium(III) complex. Plos One. 8: e60114. PMID 23533670 DOI: 10.1371/Journal.Pone.0060114  0.073
2013 Leung KH, He HZ, Ma VP, Chan DS, Leung CH, Ma DL. A luminescent G-quadruplex switch-on probe for the highly selective and tunable detection of cysteine and glutathione. Chemical Communications (Cambridge, England). 49: 771-3. PMID 23192322 DOI: 10.1039/C2Cc37710A  0.073
2015 Wang W, Kang TS, Chan PWH, Lu JJ, Chen XP, Leung CH, Ma DL. A label-free G-quadruplex-based mercury detection assay employing the exonuclease III-mediated cleavage of T-Hg2+-T mismatched DNA Science and Technology of Advanced Materials. 16. DOI: 10.1088/1468-6996/16/6/065004  0.073
2012 Ma DL, Ma VPY, Chan DSH, Leung KH, He HZ, Leung CH. Recent advances in luminescent heavy metal complexes for sensing Coordination Chemistry Reviews. 256: 3087-3113. DOI: 10.1016/J.Ccr.2012.07.005  0.073
2015 Leung CH, Liu LJ, Lu L, He B, Kwong DW, Wong CY, Ma DL. A metal-based tumour necrosis factor-alpha converting enzyme inhibitor. Chemical Communications (Cambridge, England). 51: 3973-6. PMID 25610924 DOI: 10.1039/C4Cc09251A  0.072
2017 Wei W, Li ZP, Zhu T, Fung HY, Wong TL, Wen X, Ma DL, Leung CH, Han QB. Anti-Fatigue Effects of the Unique Polysaccharide Marker of Dendrobium officinale on BALB/c Mice. Molecules (Basel, Switzerland). 22. PMID 28106808 DOI: 10.3390/Molecules22010155  0.072
2017 Miao X, Ko CN, Vellaisamy K, Li Z, Yang G, Leung CH, Ma DL. A cyclometalated iridium(III) complex used as a conductor for the electrochemical sensing of IFN-γ. Scientific Reports. 7: 42740. PMID 28198433 DOI: 10.1038/Srep42740  0.071
2012 Leung CH, Yang H, Ma VPY, Chan DSH, Zhong HJ, Li YW, Fong WF, Ma DL. Inhibition of Janus kinase 2 by cyclometalated rhodium complexes Medchemcomm. 3: 696-698. DOI: 10.1039/C2Md00306F  0.071
2016 Ma G, Luo W, Lu J, Ma DL, Leung CH, Wang Y, Chen X. Cucurbitacin E induces caspase-dependent apoptosis and protective autophagy mediated by ROS in lung cancer cells. Chemico-Biological Interactions. PMID 27106530 DOI: 10.1016/j.cbi.2016.04.028  0.071
2020 Chou HY, Ma DL, Leung CH, Chiu CC, Hour TC, Wang HD. Purified Astaxanthin from Promotes Tissue Regeneration by Reducing Oxidative Stress and the Secretion of Collagen and . Oxidative Medicine and Cellular Longevity. 2020: 4946902. PMID 32832000 DOI: 10.1155/2020/4946902  0.07
2002 Poon WS, Ng SC, Chan MT, Leung CH, Lam JM. Neurochemical changes in ventilated head-injured patients with cerebral perfusion pressure treatment failure. Acta Neurochirurgica. Supplement. 81: 335-8. PMID 12168340 DOI: 10.1007/978-3-7091-6738-0_85  0.07
2014 Zhong HJ, Liu LJ, Chong CM, Lu L, Wang M, Chan DS, Chan PW, Lee SM, Ma DL, Leung CH. Discovery of a natural product-like iNOS inhibitor by molecular docking with potential neuroprotective effects in vivo. Plos One. 9: e92905. PMID 24690920 DOI: 10.1371/Journal.Pone.0092905  0.07
2016 Chong CM, Kou MT, Pan P, Zhou H, Ai N, Li C, Zhong HJ, Leung CH, Hou T, Lee SM. Discovery of a novel ROCK2 inhibitor with anti-migration effects via docking and high-content drug screening. Molecular Biosystems. PMID 27354305 DOI: 10.1039/C6Mb00343E  0.07
2011 Ma DL, Kwan MH, Chan DS, Lee P, Yang H, Ma VP, Bai LP, Jiang ZH, Leung CH. Crystal violet as a fluorescent switch-on probe for i-motif: label-free DNA-based logic gate. The Analyst. 136: 2692-6. PMID 21566850 DOI: 10.1039/C1An15091J  0.07
2012 Liu J, Sun RW, Leung CH, Lok CN, Che CM. Inhibition of TNF-α stimulated nuclear factor-kappa B (NF-κB) activation by cyclometalated platinum(II) complexes. Chemical Communications (Cambridge, England). 48: 230-2. PMID 22085845 DOI: 10.1039/C1Cc15317J  0.07
2012 Ma DL, Shiu-Hin Chan D, Yang H, He HZ, Leung CH. Luminescent G-quadruplex probes. Current Pharmaceutical Design. 18: 2058-75. PMID 22376110 DOI: 10.2174/138161212799958314  0.07
2018 Kang TS, Zhang JT, Vellaisamy K, Ma DL, Leung CH. Recent progress and developments of iridium-based compounds as probes for environmental analytes. Dalton Transactions (Cambridge, England : 2003). PMID 30211915 DOI: 10.1039/C8Dt01167B  0.07
2017 Wang W, Vellaisamy K, Li G, Wu C, Ko CN, Leung CH, Ma DL. Development of a long-lived luminescence probe for visualizing β-galactosidase in ovarian carcinoma cells. Analytical Chemistry. PMID 28969424 DOI: 10.1021/Acs.Analchem.7B03114  0.069
2017 Liu J, Vellaisamy K, Yang G, Leung CH, Ma DL. Luminescent turn-on detection of Hg(II) via the quenching of an iridium(III) complex by Hg(II)-mediated silver nanoparticles. Scientific Reports. 7: 3620. PMID 28620192 DOI: 10.1038/S41598-017-03952-X  0.069
2008 Gao W, Chen AP, Leung CH, Gullen EA, Fürstner A, Shi Q, Wei L, Lee KH, Cheng YC. Structural analogs of tylophora alkaloids may not be functional analogs. Bioorganic & Medicinal Chemistry Letters. 18: 704-9. PMID 18077159 DOI: 10.1016/J.Bmcl.2007.11.054  0.069
2015 Liu LJ, Leung KH, Lin S, Chan DS, Susanti D, Rao W, Chan PW, Ma DL, Leung CH. Pharmacophore modeling for the identification of small-molecule inhibitors of TACE. Methods (San Diego, Calif.). 71: 92-7. PMID 25260600 DOI: 10.1016/j.ymeth.2014.09.005  0.069
2014 Wang M, Leung KH, Lin S, Chan DS, Kwong DW, Leung CH, Ma DL. A colorimetric chemosensor for Cu²⁺ ion detection based on an iridium(III) complex. Scientific Reports. 4: 6794. PMID 25348724 DOI: 10.1038/Srep06794  0.069
2011 Wang N, Feng Y, Xie TN, Su W, Zhu M, Chow O, Zhang Y, Ng KM, Leung CH, Tong Y. Chemical and biological analysis of active free and conjugated bile acids in animal bile using HPLC-ELSD and MTT methods. Experimental and Therapeutic Medicine. 2: 125-130. PMID 22977479 DOI: 10.3892/etm.2010.178  0.069
2015 Zhong Z, Liu LJ, Dong ZQ, Lu L, Wang M, Leung CH, Ma DL, Wang Y. Structure-based discovery of an immunomodulatory inhibitor of TLR1-TLR2 heterodimerization from a natural product-like database. Chemical Communications (Cambridge, England). 51: 11178-81. PMID 26051605 DOI: 10.1039/C5Cc02728D  0.069
2017 Ng SW, Chung LH, Yeung CF, Lo HS, Shek HL, Kang TS, Leung CH, Wong CY. Metalated Chromene and Chromone Complexes: pH Switchable Metal-Carbon Bonding Interaction, Photo-Triggerable Chromone Delivery Application, and Antioxidative Activity. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29160601 DOI: 10.1002/Chem.201705450  0.069
2010 Sun R, Li C, Ma D, Yan J, Lok C, Leung C, Zhu N, Che C. Cover Picture: Stable Anticancer Gold(III)-Porphyrin Complexes: Effects of Porphyrin Structure (Chem. Eur. J. 10/2010) Chemistry - a European Journal. 16: 2951-2951. DOI: 10.1002/Chem.201090039  0.069
2015 Chan SL, Lu L, Lam TL, Yan SC, Leung CH, Ma DL. A Novel Tetradentate Ruthenium(II) Complex Containing Tris(2- pyridylmethyl)amine (tpa) as an Inhibitor of Beta-Amyloid Fibrillation. Current Alzheimer Research. 12: 434-8. PMID 25938869  0.069
2017 Wu KJ, Huang JM, Zhong HJ, Dong ZZ, Vellaisamy K, Lu JJ, Chen XP, Chiu P, Kwong DWJ, Han QB, Ma DL, Leung CH. A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells. Plos One. 12: e0177123. PMID 28570563 DOI: 10.1371/Journal.Pone.0177123  0.068
2019 Leung CH, Zhang JT, Yang GJ, Liu H, Han QB, Ma DL. Emerging Screening Approaches in the Development of Nrf2-Keap1 Protein-Protein Interaction Inhibitors. International Journal of Molecular Sciences. 20. PMID 31509940 DOI: 10.3390/Ijms20184445  0.068
2016 Yang C, Wang W, Chen L, Liang J, Lin S, Lee MY, Ma DL, Leung CH. Discovery of a VHL and HIF1α interaction inhibitor with in vivo angiogenic activity via structure-based virtual screening. Chemical Communications (Cambridge, England). PMID 27709157 DOI: 10.1039/C6Cc04938A  0.067
2010 Man BY, Chan DS, Yang H, Ang SW, Yang F, Yan SC, Ho CM, Wu P, Che CM, Leung CH, Ma DL. A selective G-quadruplex-based luminescent switch-on probe for the detection of nanomolar silver(I) ions in aqueous solution. Chemical Communications (Cambridge, England). 46: 8534-6. PMID 20668746 DOI: 10.1039/C0Cc01201G  0.067
2010 Yan JJ, Chow AL, Leung CH, Sun RW, Ma DL, Che CM. Cyclometalated gold(III) complexes with N-heterocyclic carbene ligands as topoisomerase I poisons. Chemical Communications (Cambridge, England). 46: 3893-5. PMID 20401423 DOI: 10.1039/C001216E  0.066
2018 Liu J, Bao H, Ma DL, Leung CH. Silver nanoclusters functionalized with Ce(III) ions are a viable "turn-on-off" fluorescent probe for sulfide. Mikrochimica Acta. 186: 16. PMID 30542774 DOI: 10.1007/S00604-018-3149-Z  0.066
1998 Leung CH, Suen CY. Matching of complex patterns by energy minimization. Ieee Transactions On Systems, Man, and Cybernetics. Part B, Cybernetics : a Publication of the Ieee Systems, Man, and Cybernetics Society. 28: 712-20. PMID 18255989 DOI: 10.1109/3477.718520  0.066
2012 Ye D, Shi Q, Leung CH, Kim SW, Park SY, Gullen EA, Jiang ZL, Zhu H, Morris-Natschke SL, Cheng YC, Lee KH. Antitumor agents 294. Novel E-ring-modified camptothecin-4β-anilino-4'-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase I inhibitors and cytotoxic agents. Bioorganic & Medicinal Chemistry. 20: 4489-94. PMID 22698783 DOI: 10.1016/J.Bmc.2012.05.030  0.066
2009 Chan DS, Lee HM, Che CM, Leung CH, Ma DL. A selective oligonucleotide-based luminescent switch-on probe for the detection of nanomolar mercury(II) ion in aqueous solution. Chemical Communications (Cambridge, England). 7479-81. PMID 20024252 DOI: 10.1039/B913995H  0.066
2016 Sun W, Bao J, Lin W, Gao H, Zhao W, Zhang Q, Leung CH, Ma DL, Lu J, Chen X. 2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells. Free Radical Biology & Medicine. PMID 26802903 DOI: 10.1016/j.freeradbiomed.2016.01.014  0.065
2012 Leung KH, Ma VPY, He HZ, Chan DSH, Yang H, Leung CH, Ma DL. A highly selective G-quadruplex-based luminescent switch-on probe for the detection of nanomolar strontium(ii) ions in sea water Rsc Advances. 2: 8273-8276. DOI: 10.1039/C2Ra21119J  0.065
2017 Liu LJ, Wang W, Huang SY, Hong Y, Li G, Lin S, Tian J, Cai Z, Wang HD, Ma DL, Leung CH. Inhibition of the Ras/Raf interaction and repression of renal cancer xenografts in vivo by an enantiomeric iridium(iii) metal-based compound. Chemical Science. 8: 4756-4763. PMID 28959398 DOI: 10.1039/C7Sc00311K  0.065
2015 Gao H, Sun W, Zhao W, Hao W, Leung CH, Lu J, Chen X. Total Tanshinones-Induced Apoptosis and Autophagy Via Reactive Oxygen Species in Lung Cancer 95D Cells. The American Journal of Chinese Medicine. 1-15. PMID 26394653 DOI: 10.1142/S0192415X1550072X  0.065
2014 Ma DL, Chan DS, Wei G, Zhong HJ, Yang H, Leung LT, Gullen EA, Chiu P, Cheng YC, Leung CH. Virtual screening and optimization of Type II inhibitors of JAK2 from a natural product library. Chemical Communications (Cambridge, England). 50: 13885-8. PMID 25225654 DOI: 10.1039/C4Cc04498C  0.065
2014 Ma D, Liu L, Leung K, Chen Y, Zhong H, Chan DS, Wang HD, Leung C. Rücktitelbild: Antagonizing STAT3 Dimerization with a Rhodium(III) Complex (Angew. Chem. 35/2014) Angewandte Chemie. 126: 9544-9544. DOI: 10.1002/Ange.201406152  0.064
2017 Fung HY, Lang Y, Ho HM, Wong TL, Ma DL, Leung CH, Han QB. Comprehensive Quantitative Analysis of 32 Chemical Ingredients of a Chinese Patented Drug Sanhuang Tablet. Molecules (Basel, Switzerland). 22. PMID 28085113 DOI: 10.3390/Molecules22010111  0.064
2013 Ma DL, He HZ, Chan DSH, Leung CH. Simple DNA-based logic gates responding to biomolecules and metal ions Chemical Science. 4: 3366-3380. DOI: 10.1039/C3Sc50924A  0.064
2015 Wei W, Xiao HT, Bao WR, Ma DL, Leung CH, Han XQ, Ko CH, Lau CB, Wong CK, Fung KP, Leung PC, Bian ZX, Han QB. TLR-4 may mediate signaling pathways of Astragalus polysaccharide RAP induced cytokine expression of RAW264.7 cells. Journal of Ethnopharmacology. PMID 26743224 DOI: 10.1016/J.Jep.2015.12.060  0.064
2016 Guo S, Luo W, Liu L, Pang X, Zhu H, Liu A, Lu J, Ma DL, Leung CH, Wang Y, Chen X. Isocryptotanshinone, a STAT3 inhibitor, induces apoptosis and pro-death autophagy in A549 lung cancer cells. Journal of Drug Targeting. 1-28. PMID 26904961 DOI: 10.3109/1061186X.2016.1157882  0.063
2020 Wu KJ, Wang W, Wang HD, Leung CH, Ma DL. Interfering with S100B-effector protein interactions for cancer therapy. Drug Discovery Today. PMID 32679172 DOI: 10.1016/J.Drudis.2020.07.010  0.062
2015 Cheng SP, Liu CL, Chen MJ, Chien MN, Leung CH, Lin CH, Hsu YC, Lee JJ. CD74 expression and its therapeutic potential in thyroid carcinoma. Endocrine-Related Cancer. 22: 179-90. PMID 25600560 DOI: 10.1530/ERC-14-0269  0.062
2012 He HZ, Leung KH, Fu WC, Chan DSH, Leung CH, Ma DL. Application of a DNA-based luminescence switch-on method for the detection of mercury(II) ions in water samples from Hong Kong Environmental Research Letters. 7. DOI: 10.1088/1748-9326/7/4/044032  0.062
2016 Miao X, Wang W, Kang T, Liu J, Shiu KK, Leung CH, Ma DL. Ultrasensitive electrochemical detection of miRNA-21 by using an iridium(III) complex as catalyst. Biosensors & Bioelectronics. 86: 454-458. PMID 27424263 DOI: 10.1016/J.Bios.2016.07.001  0.062
2016 Wei W, Feng L, Bao WR, Ma DL, Leung CH, Nie SP, Han QB. Structure characterization and immunomodulating effects of polysaccharides isolated from Dendrobium officinale. Journal of Agricultural and Food Chemistry. PMID 26752248 DOI: 10.1021/acs.jafc.5b05180  0.062
2016 Liu LJ, He B, Miles JA, Wang W, Mao Z, Che WI, Lu JJ, Chen XP, Wilson AJ, Ma DL, Leung CH. Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds. Oncotarget. PMID 26883110 DOI: 10.18632/Oncotarget.7369  0.062
2015 Leung Ch. Enhancing Social Competence and the Child–Teacher Relationship using a Child-Centred Play Training Model in Hong Kong Preschools International Journal of Early Childhood. 47: 135-152. DOI: 10.1007/s13158-014-0117-6  0.062
2015 Chung LH, Lo HS, Ng SW, Ma DL, Leung CH, Wong CY. Luminescent Iridium(III) Complexes Supported by N-Heterocyclic Carbene-based C^C^C-Pincer Ligands and Aromatic Diimines. Scientific Reports. 5: 15394. PMID 26487542 DOI: 10.1038/srep15394  0.062
2015 Leung CH, Lin S, Zhong HJ, Ma DL. Metal complexes as potential modulators of inflammatory and autoimmune responses Chemical Science. 6: 871-884. DOI: 10.1039/c4sc03094j  0.062
2014 Ma D, Liu L, Leung K, Chen Y, Zhong H, Chan DS, Wang HD, Leung C. Back Cover: Antagonizing STAT3 Dimerization with a Rhodium(III) Complex (Angew. Chem. Int. Ed. 35/2014) Angewandte Chemie International Edition. 53: 9390-9390. DOI: 10.1002/Anie.201406152  0.062
2016 Ren G, Luo W, Sun W, Niu Y, Ma DL, Leung CH, Wang Y, Lu JJ, Chen X. Psoralidin induced reactive oxygen species (ROS)-dependent DNA damage and protective autophagy mediated by NOX4 in breast cancer cells. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 23: 939-47. PMID 27387402 DOI: 10.1016/j.phymed.2016.05.008  0.062
2019 Wong TL, Li LF, Zhang JX, Bai SP, Zhou LS, Fung HY, Zhang QW, Ma DL, Leung CH, Zhao ZZ, Han QB. Oligosaccharide-marker approach for qualitative and quantitative analysis of specific polysaccharide in herb formula by ultra-high-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry: Dendrobium officinale, a case study. Journal of Chromatography. A. 460388. PMID 31351593 DOI: 10.1016/J.Chroma.2019.460388  0.061
2017 Liu LJ, Wang W, Zhong Z, Lin S, Lu L, Wang YT, Ma DL, Leung CH. Correction: Inhibition of TLR1/2 dimerization by enantiomers of metal complexes. Chemical Communications (Cambridge, England). PMID 28075430 DOI: 10.1039/C7Cc90024D  0.061
2019 Wu KJ, Liu X, Wong SY, Zhou Y, Ma DL, Leung CH. Synthesis and Evaluation of Dibenzothiophene Analogues as Pin1 Inhibitors for Cervical Cancer Therapy. Acs Omega. 4: 9228-9234. PMID 31460012 DOI: 10.1021/acsomega.9b00281  0.061
2015 Tang ZH, Zhang LL, Li T, Lu JH, Ma DL, Leung CH, Chen XP, Jiang HL, Wang YT, Lu JJ. Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-terminal kinase cascade in non-small cell lung cancer cells. Oncotarget. PMID 26549806 DOI: 10.18632/Oncotarget.6084  0.06
2006 Sun DT, Poon WS, Leung CH, Lam JM. Management of spinal injury. The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 4: 293-7. PMID 17009548 DOI: 10.1016/S1479-666X(06)80006-5  0.06
2018 Li ZP, Liu HB, Zhang QW, Li LF, Bao WR, Ma DL, Leung CH, Bian ZX, Lu AP, Han QB. Interference of Quercetin on Astragalus Polysaccharide-Induced Macrophage Activation. Molecules (Basel, Switzerland). 23. PMID 29958399 DOI: 10.3390/Molecules23071563  0.06
2006 Choi S, Vastag L, Leung CH, Beard AM, Knowles DE, Larrabee JA. Kinetics and mechanism of the oxidation of guanosine derivatives by Pt(IV) complexes. Inorganic Chemistry. 45: 10108-14. PMID 17140216 DOI: 10.1021/ic061243g  0.059
2013 Leung CH, Chan DS, Li YW, Fong WF, Ma DL. Hit identification of IKKβ natural product inhibitor. Bmc Pharmacology & Toxicology. 14: 3. PMID 23294515 DOI: 10.1186/2050-6511-14-3  0.059
2015 Zhang TB, Yue RQ, Xu J, Ho HM, Ma DL, Leung CH, Chau SL, Zhao ZZ, Chen HB, Han QB. Comprehensive quantitative analysis of Shuang-Huang-Lian oral liquid using UHPLC-Q-TOF-MS and HPLC-ELSD. Journal of Pharmaceutical and Biomedical Analysis. 102: 1-8. PMID 25222137 DOI: 10.1016/J.Jpba.2014.08.025  0.058
2011 Ma DL, Chan DS, Man BY, Leung CH. Oligonucleotide-based luminescent detection of metal ions. Chemistry, An Asian Journal. 6: 986-1003. PMID 21337527 DOI: 10.1002/Asia.201000870  0.058
2001 Fong WF, Leung CH, Lam W, Wong NS, Cheng SH. Epidermal growth factor induces Gadd45 (growth arrest and DNA damage inducible protein) expression in A431 cells. Biochimica Et Biophysica Acta. 1517: 250-6. PMID 11342106  0.058
2015 Lin S, Gao W, Tian Z, Yang C, Lu L, Mergny JL, Leung CH, Ma DL. Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe Chemical Science. 6: 4284-4290. DOI: 10.1039/c5sc01320h  0.058
2011 Ma DL, Chan DSH, Leung CH. Molecular docking for virtual screening of natural product databases Chemical Science. 2: 1656-1665. DOI: 10.1039/C1Sc00152C  0.057
2008 Hui KN, Fu WY, Ng WN, Leung CH, Lai PT, Wong KK, Choi HW. Polychromatic light-emitting diodes with a fluorescent nanosphere opal coating. Nanotechnology. 19: 355203. PMID 21828836 DOI: 10.1088/0957-4484/19/35/355203  0.057
2019 Yang GJ, Liu H, Ma DL, Leung CH. Rebalancing metal dyshomeostasis for Alzheimer's disease therapy. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 31486954 DOI: 10.1007/S00775-019-01712-Y  0.057
2013 Ma DL, Leung CH. Editorial for "Recent advances in DNA-based biosensor". Methods (San Diego, Calif.). 64: 183-4. PMID 24296311 DOI: 10.1016/J.Ymeth.2013.11.005  0.057
2013 Ma DL, Chan DS, Leung CH. Drug repositioning by structure-based virtual screening. Chemical Society Reviews. 42: 2130-41. PMID 23288298 DOI: 10.1039/C2Cs35357A  0.056
2011 Leung CH, Chan DS, Yang H, Abagyan R, Lee SM, Zhu GY, Fong WF, Ma DL. A natural product-like inhibitor of NEDD8-activating enzyme. Chemical Communications (Cambridge, England). 47: 2511-3. PMID 21240405 DOI: 10.1039/C0Cc04927A  0.056
2005 Cheng YC, Ying CX, Leung CH, Li Y. New targets and inhibitors of HBV replication to combat drug resistance. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 34: S147-50. PMID 16461217  0.056
2016 Lin X, Leung KH, Lin L, Lin S, Leung CH, Ma DL, Lin JM. Determination of cell metabolite VEGF165 and dynamic analysis of protein-DNA interactions by combination of microfluidic technique and luminescent switch-on probe Biosensors and Bioelectronics. 79: 41-47. DOI: 10.1016/j.bios.2015.11.089  0.056
2005 Hui AC, Wong S, Leung CH, Tong P, Mok V, Poon D, Li-Tsang CW, Wong LK, Boet R. A randomized controlled trial of surgery vs steroid injection for carpal tunnel syndrome. Neurology. 64: 2074-8. PMID 15985575 DOI: 10.1212/01.Wnl.0000169017.79374.93  0.055
2013 Leung CH, Zhong HJ, He HZ, Lu L, Chan DSH, Ma DL. Luminescent oligonucleotide-based detection of enzymes involved with DNA repair Chemical Science. 4: 3781-3795. DOI: 10.1039/C3Sc51228B  0.054
2015 Lee MG, Kuo SY, Yen SY, Hsu HF, Leung CH, Ma DL, Wen ZH, Wang HM. Evaluation of Cinnamomum osmophloeum Kanehira extracts on tyrosinase suppressor, wound repair promoter, and antioxidant. Thescientificworldjournal. 2015: 303415. PMID 25839053 DOI: 10.1155/2015/303415  0.054
2010 Chan DS, Lee HM, Yang F, Che CM, Wong CC, Abagyan R, Leung CH, Ma DL. Structure-based discovery of natural-product-like TNF-α inhibitors. Angewandte Chemie (International Ed. in English). 49: 2860-4. PMID 20235259 DOI: 10.1002/Anie.200907360  0.054
2012 Ma D, Chan DS, Fu W, He H, Yang H, Yan S, Leung C. Correction: Discovery of a Natural Product-Like c-myc G-Quadruplex DNA Groove-Binder by Molecular Docking Plos One. 7. DOI: 10.1371/Annotation/632F2B99-Dd0B-443E-9269-1156D0E7521F  0.053
2015 Zhong HJ, Lu L, Leung KH, Wong CCL, Peng C, Yan SC, Ma DL, Cai Z, David Wang HM, Leung CH. An iridium(III)-based irreversible protein-protein interaction inhibitor of BRD4 as a potent anticancer agent Chemical Science. 6: 5400-5408. DOI: 10.1039/c5sc02321a  0.053
2010 Feng Y, Siu KY, Ye X, Wang N, Yuen MF, Leung CH, Tong Y, Kobayashi S. Hepatoprotective effects of berberine on carbon tetrachloride-induced acute hepatotoxicity in rats. Chinese Medicine. 5: 33. PMID 20849653 DOI: 10.1186/1749-8546-5-33  0.052
2007 Fong WF, Wang C, Zhu GY, Leung CH, Yang MS, Cheung HY. Reversal of multidrug resistance in cancer cells by Rhizoma Alismatis extract. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 14: 160-5. PMID 16713217 DOI: 10.1016/j.phymed.2006.03.004  0.052
2016 Niu Y, Sun W, Lu JJ, Ma DL, Leung CH, Pei L, Chen X. PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells. Oxidative Medicine and Cellular Longevity. 2016: 4313204. PMID 28042385 DOI: 10.1155/2016/4313204  0.052
2015 Ma DL, Zhang Z, Wang M, Lu L, Zhong HJ, Leung CH. Recent Developments in G-Quadruplex Probes Chemistry and Biology. 22: 812-828. DOI: 10.1016/j.chembiol.2015.06.016  0.052
2016 Wu CS, Wei KL, Chou JL, Lu CK, Hsieh CC, Lin JM, Deng YF, Hsu WT, Wang HD, Leung CH, Ma DL, Li C, Chan MW. Aberrant JAK/STAT Signaling Suppresses TFF1 and TFF2 through Epigenetic Silencing of GATA6 in Gastric Cancer. International Journal of Molecular Sciences. 17. PMID 27598141 DOI: 10.3390/Ijms17091467  0.052
2012 Li L, Mak KY, Shi J, Koon HK, Leung CH, Wong CM, Leung CW, Mak CS, Chan NM, Zhong W, Lin KW, Wu EX, Pong PW. Comparative in vitro cytotoxicity study on uncoated magnetic nanoparticles: effects on cell viability, cell morphology, and cellular uptake. Journal of Nanoscience and Nanotechnology. 12: 9010-7. PMID 23447952 DOI: 10.1166/Jnn.2012.6755  0.051
2016 Li PH, Chiu YP, Shih CC, Wen ZH, Ibeto LK, Huang SH, Chiu CC, Ma DL, Leung CH, Chang YN, Wang HM. Biofunctional Activities of Equisetum ramosissimum Extract: Protective Effects against Oxidation, Melanoma, and Melanogenesis. Oxidative Medicine and Cellular Longevity. 2016: 2853543. PMID 27403230 DOI: 10.1155/2016/2853543  0.051
2016 Hu C, Lin S, Li W, Sun H, Chen Y, Chan CW, Leung CH, Ma DL, Wu H, Ren K. A one-step strategy for ultra-fast and low-cost mass production of plastic membrane microfluidic chips. Lab On a Chip. 16: 3909-3918. PMID 27722382 DOI: 10.1039/c6lc00957c  0.05
2017 Liu JB, Wang W, Li G, Wang RX, Leung CH, Ma DL. Luminescent Iridium(III) Chemosensor for Tandem Detection of F and Al. Acs Omega. 2: 9150-9155. PMID 31457433 DOI: 10.1021/acsomega.7b01646  0.05
2016 Wong TL, An YQ, Yan BC, Yue RQ, Zhang TB, Ho HM, Ren TJ, Fung HY, Ma DL, Leung CH, Liu ZL, Pu JX, Han QB, Sun HD. Comprehensive quantitative analysis of Chinese patent drug YinHuang drop pill by ultra high-performance liquid chromatography quadrupole time of flight mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 125: 415-426. PMID 27131804 DOI: 10.1016/J.Jpba.2016.04.008  0.049
2018 He J, Chen K, Hu ZM, Li K, Song W, Yu LY, Leung CH, Ma DL, Qiao X, Ye M. UGT73F17, a new glycosyltransferase from Glycyrrhiza uralensis, catalyzes the regiospecific glycosylation of pentacyclic triterpenoids. Chemical Communications (Cambridge, England). PMID 30010690 DOI: 10.1039/C8Cc04215B  0.049
2012 Ma DL, Chan DS, Ma VP, Leung KH, Zhong HJ, Leung CH. Current advancements in Aβ luminescent probes and inhibitors of Aβ aggregation. Current Alzheimer Research. 9: 830-43. PMID 22631884 DOI: 10.2174/156720512802455377  0.048
2001 Poon WS, Leung CH, Lam MK, Wai S, Ng CP, Kwok S. The comparative impact of video-consultation on neurosurgical health services. International Journal of Medical Informatics. 62: 175-80. PMID 11470620 DOI: 10.1016/S1386-5056(01)00161-7  0.048
2019 Li B, Kuang Y, He JB, Tang R, Xu LL, Leung CH, Ma DL, Qiao X, Ye M. Antcamphorols A-K, Cytotoxic and ROS Scavenging Triterpenoids from . Journal of Natural Products. PMID 31891260 DOI: 10.1021/Acs.Jnatprod.9B00580  0.047
2019 Li D, Liu Q, Lu X, Li Z, Wang C, Leung CH, Wang Y, Peng C, Lin L. α-Mangostin remodels visceral adipose tissue inflammation to ameliorate age-related metabolic disorders in mice. Aging. 11. PMID 31806859 DOI: 10.18632/aging.102512  0.047
2015 Ma DL, Wang W, Mao Z, Yang C, Chen XP, Lu JJ, Han QB, Leung CH. A tutorial review for employing enzymes for the construction of G-quadruplex-based sensing platforms Analytica Chimica Acta. DOI: 10.1016/j.aca.2016.01.043  0.047
2020 Li LF, Wong TL, Zhang JX, Zhou LS, Bai SP, Fung HY, Cheng HY, Zhang QW, Zheng HM, Bao WR, Ma DL, Leung CH, Zhang G, Bian ZX, Lyu AP, et al. An oligosaccharide-marker approach to quantify specific polysaccharides in herbal formula by LC-qTOF-MS: Danggui Buxue Tang, a case study. Journal of Pharmaceutical and Biomedical Analysis. 185: 113235. PMID 32182447 DOI: 10.1016/J.Jpba.2020.113235  0.047
2016 Li XJ, Bao WR, Leung CH, Ma DL, Zhang G, Lu AP, Wang SC, Han QB. Chemical Structure and Immunomodulating Activities of an α-Glucan Purified from Lobelia chinensis Lour. Molecules (Basel, Switzerland). 21. PMID 27314319 DOI: 10.3390/molecules21060779  0.047
2014 Liu MS, Chau SL, Ma DL, Leung CH, Bian ZX, Lu AP, Xu HX, Han QB. Using two-phase solvent systems for sample pretreatment increases yield of counter-current chromatography: Anemarrhena asphodeloides saponins, a case study Separation and Purification Technology. 138: 138-143. DOI: 10.1016/J.Seppur.2014.10.011  0.046
2017 Sun H, Li W, Dong ZZ, Hu C, Leung CH, Ma DL, Ren K. A suspending-droplet mode paper-based microfluidic platform for low-cost, rapid, and convenient detection of lead(II) ions in liquid solution. Biosensors & Bioelectronics. 99: 361-367. PMID 28800508 DOI: 10.1016/J.Bios.2017.07.073  0.046
2018 Ma D, Wu C, Li G, Leung C. Group 8–9 Metal-Based Luminescent Chemosensors for Protein Biomarker Detection Journal of Analysis and Testing. 2: 77-89. DOI: 10.1007/s41664-017-0045-1  0.045
2012 Wong GK, Kam MK, Chiu SK, Lam JM, Leung CH, Ng DW, Ngar YK, Poon WS. Validation of the modified radiosurgery-based arteriovenous malformation score in a linear accelerator radiosurgery experience in Hong Kong. Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia. 19: 1252-4. PMID 22784875 DOI: 10.1016/j.jocn.2012.01.010  0.044
2008 Kwok FY, Lee TM, Leung CH, Poon WS. Changes of cognitive functioning following mild traumatic brain injury over a 3-month period. Brain Injury. 22: 740-51. PMID 18787983 DOI: 10.1080/02699050802336989  0.044
2014 Leung CH, Tseng HK, Wang WS, Chiang HT, Wu AY, Liu CP. Clinical characteristics of children and adults hospitalized for influenza virus infection. Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi. 47: 518-25. PMID 23932366 DOI: 10.1016/j.jmii.2013.06.002  0.043
2014 Kato H, Fu YY, Zhu J, Wang L, Aafaqi S, Rahkonen O, Slorach C, Traister A, Leung CH, Chiasson D, Mertens L, Benson L, Weisel RD, Hinz B, Maynes JT, et al. Pulmonary vein stenosis and the pathophysiology of "upstream" pulmonary veins. The Journal of Thoracic and Cardiovascular Surgery. 148: 245-53. PMID 24084286 DOI: 10.1016/J.Jtcvs.2013.08.046  0.043
2016 Kang TS, Wang W, Zhong HJ, Liang JX, Ko CN, Lu JJ, Chen XP, Ma DL, Leung CH. A rhodium(III)-based inhibitor of autotaxin with antiproliferative activity. Biochimica Et Biophysica Acta. PMID 27888146 DOI: 10.1016/J.Bbagen.2016.11.032  0.042
2015 Li T, Xu XH, Tang ZH, Wang YF, Leung CH, Ma DL, Chen XP, Wang YT, Chen Y, Lu JJ. Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells. Acta Pharmacologica Sinica. PMID 26592509 DOI: 10.1038/Aps.2015.99  0.042
2011 Liu CK, Liu CP, Leung CH, Sun FJ. Clinical and microbiological analysis of adult perianal abscess. Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi. 44: 204-8. PMID 21524615 DOI: 10.1016/j.jmii.2011.01.024  0.042
2005 Lam W, Chen C, Ruan S, Leung CH, Cheng YC. Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake. Molecular Pharmacology. 67: 408-16. PMID 15539640 DOI: 10.1124/mol.104.007120  0.041
2006 Wong HT, Poon WS, Jacobs P, Goh KY, Leung CH, Lau FL, Kwok S, Ng S, Chow L. The comparative impact of video consultation on emergency neurosurgical referrals. Neurosurgery. 59: 607-13; discussion 6. PMID 16955042 DOI: 10.1227/01.Neu.0000228926.13395.F9  0.041
2010 Tay PN, Tan P, Lan Y, Leung CH, Laban M, Tan TC, Ni H, Manikandan J, Rashid SB, Yan B, Yap CT, Lim LH, Lim YC, Hooi SC. Palladin, an actin-associated protein, is required for adherens junction formation and intercellular adhesion in HCT116 colorectal cancer cells. International Journal of Oncology. 37: 909-26. PMID 20811713  0.04
2014 Zhang X, Teo JW, Ma DL, Leung CH, Chan PWH. Ytterbium(III) triflate catalyzed annulation of propargylic 1,4-diols with aryl sulfonamides to give highly substituted pyrrole derivatives Tetrahedron Letters. 55: 6703-6707. DOI: 10.1016/j.tetlet.2014.10.042  0.04
1981 Leung CH, Tu CH. Welfare effects of international migration. Jing Ji Lun Wen. 9: 161-9. PMID 12229837  0.039
2015 Ma DL, Chan DS, Wei G, Zhong HJ, Yang H, Leung LT, Gullen EA, Chiu P, Cheng YC, Leung CH. Correction: Virtual screening and optimization of Type II inhibitors of JAK2 from a natural product library. Chemical Communications (Cambridge, England). 51: 959. PMID 25429723 DOI: 10.1039/C4Cc90479F  0.039
2015 Leung CH. Factor structure of PPBS with Chinese preschoolers from low-income families Children and Youth Services Review. 53: 157-165. DOI: 10.1016/j.childyouth.2015.04.002  0.039
2004 Zhuang WJ, Fong CC, Cao J, Ao L, Leung CH, Cheung HY, Xiao PG, Fong WF, Yang MS. Involvement of NF-kappaB and c-myc signaling pathways in the apoptosis of HL-60 cells induced by alkaloids of Tripterygium hypoglaucum (levl.) Hutch. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 11: 295-302. PMID 15185841  0.038
2007 Lam W, Leung CH, Bussom S, Cheng YC. The impact of hypoxic treatment on the expression of phosphoglycerate kinase and the cytotoxicity of troxacitabine and gemcitabine. Molecular Pharmacology. 72: 536-44. PMID 17565005 DOI: 10.1124/mol.106.033472  0.038
2011 Leung CH, Chan DS, Kwan MH, Cheng Z, Wong CY, Zhu GY, Fong WF, Ma DL. Structure-based repurposing of FDA-approved drugs as TNF-α inhibitors. Chemmedchem. 6: 765-8. PMID 21365767 DOI: 10.1002/Cmdc.201100016  0.037
2008 Arnold RG, Teske S, Tomanek M, Engstrom J, Leung C, Zhang J, Banihani Q, Quanrud D, Ela WP, Sáez AE. Fate of polybrominated diphenyl ethers during wastewater treatment/polishing and sludge stabilization/disposal. Annals of the New York Academy of Sciences. 1140: 394-411. PMID 18991940 DOI: 10.1196/Annals.1454.012  0.036
2015 Tejo C, Sim XR, Lee BR, Ayers BJ, Leung CH, Ma DL, Chan PW. Iminoiodane- and Brønsted base-mediated cross dehydrogenative coupling of cyclic ethers with 1,3-dicarbonyl compounds. Molecules (Basel, Switzerland). 20: 13336-53. PMID 26205058 DOI: 10.3390/molecules200713336  0.036
2013 Park FJ, Leung CH, Poon LC, Williams PF, Rothwell SJ, Hyett JA. Clinical evaluation of a first trimester algorithm predicting the risk of hypertensive disease of pregnancy. The Australian & New Zealand Journal of Obstetrics & Gynaecology. 53: 532-9. PMID 23919594 DOI: 10.1111/ajo.12126  0.035
2010 Lu GD, Leung CH, Yan B, Tan CM, Low SY, Aung MO, Salto-Tellez M, Lim SG, Hooi SC. C/EBPalpha is up-regulated in a subset of hepatocellular carcinomas and plays a role in cell growth and proliferation. Gastroenterology. 139: 632-43, 643.e1-4. PMID 20347819 DOI: 10.1053/j.gastro.2010.03.051  0.034
2002 Leung CH, Poon WS, Yu LM, Wong GK, Ng HK. Apolipoprotein e genotype and outcome in aneurysmal subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 33: 548-52. PMID 11823668 DOI: 10.1161/HS0202.102326  0.034
2015 Tejo C, Sim XR, Lee BR, Ayers BJ, Leung CH, Ma DL, Chan PWH. Iminoiodane- and Brønsted base-mediated cross dehydrogenative coupling of cyclic ethers with 1,3-dicarbonyl compounds Molecules. 20: 13336-13353. DOI: 10.3390/molecules200713336  0.034
2015 Ma DL, Leung CH. Small molecule therapeutics for Alzheimer’s disease Current Alzheimer Research. 12: 400-402.  0.034
2015 Leung CH, Ma DL. Recent advances in virtual screening for drug discovery. Methods (San Diego, Calif.). 71: 1-3. PMID 25542642 DOI: 10.1016/J.Ymeth.2014.12.012  0.033
2013 Leung KC, Leung CH. Fingerprint retrieval by spatial modelling and distorted sample generation Iet Computer Vision. 7: 425-436. DOI: 10.1049/iet-cvi.2011.0161  0.032
2015 Han CY, Tang WM, Leung CH, Che CM, Lai PT. A study on la incorporation in transition-metal (Y, Zr, and Nb) oxides as gate dielectric of pentacene organic thin-film transistor Ieee Transactions On Electron Devices. 62: 2313-2319. DOI: 10.1109/Ted.2015.2432080  0.032
2014 Leung CH. Validation of the Penn Interactive Peer Play Scale with preschool children in low-income families in Hong Kong Early Child Development and Care. 184: 118-137. DOI: 10.1080/03004430.2013.773990  0.032
2001 Leung CH, Lam W, Zhuang WJ, Wong NS, Yang MS, Fong WF. PKCdelta-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF. Biochemical and Biophysical Research Communications. 285: 283-8. PMID 11444839 DOI: 10.1006/bbrc.2001.5164  0.031
2015 Ma DL, Leung CH. Editorial: small molecule therapeutics for Alzheimer's disease. Current Alzheimer Research. 12: 400-2. PMID 26017557 DOI: 10.2174/156720501205150526115737  0.031
1993 Ham FS, Leung CH. Dynamic Jahn-Teller effect for a double acceptor or acceptor-bound exciton in semiconductors: Mechanism for an inverted level ordering. Physical Review Letters. 71: 3186-3189. PMID 10054879  0.03
2011 Zhu GY, Li YW, Tse AK, Hau DK, Leung CH, Yu ZL, Fong WF. 20(S)-Protopanaxadiol, a metabolite of ginsenosides, induced cell apoptosis through endoplasmic reticulum stress in human hepatocarcinoma HepG2 cells. European Journal of Pharmacology. 668: 88-98. PMID 21703260 DOI: 10.1016/j.ejphar.2011.06.008  0.03
2015 Ler SY, Leung CH, Khin LW, Lu GD, Salto-Tellez M, Hartman M, Iau PT, Yap CT, Hooi SC. HDAC1 and HDAC2 independently predict mortality in hepatocellular carcinoma by a competing risk regression model in a Southeast Asian population. Oncology Reports. 34: 2238-50. PMID 26352599 DOI: 10.3892/or.2015.4263  0.028
2008 Gnanamgari D, Leung CH, Schley ND, Hilton ST, Crabtree RH. Alcohol cross-coupling reactions catalyzed by Ru and Ir terpyridine complexes. Organic & Biomolecular Chemistry. 6: 4442-5. PMID 19005605 DOI: 10.1039/B815547J  0.028
2010 Tang WM, Leung CH, Lai PT. Effects of N2-annealing conditions on the sensing properties of Pt/HfO2/SiC Schottky-diode hydrogen sensor Thin Solid Films. 519: 505-511. DOI: 10.1016/j.tsf.2010.08.090  0.028
1999 Sun DT, Poon WS, Lam JM, Leung CH, Kwok SP. Spontaneous intracerebral haematoma with rapidly deteriorating level of consciousness: treatment by a mobile neurosurgeon. Journal of Telemedicine and Telecare. 5: 257-9. PMID 10829379  0.027
2005 Huang BH, Laban M, Leung CH, Lee L, Lee CK, Salto-Tellez M, Raju GC, Hooi SC. Inhibition of histone deacetylase 2 increases apoptosis and p21Cip1/WAF1 expression, independent of histone deacetylase 1. Cell Death and Differentiation. 12: 395-404. PMID 15665816 DOI: 10.1038/sj.cdd.4401567  0.026
2014 Leung CH, Caldarone CA, Wang F, Venkateswaran S, Ailenberg M, Vadasz B, Wen XY, Rotstein OD. Remote Ischemic Conditioning Prevents Lung and Liver Injury After Hemorrhagic Shock/Resuscitation: Potential Role of a Humoral Plasma Factor. Annals of Surgery. PMID 25185480 DOI: 10.1097/SLA.0000000000000877  0.026
2014 Luk STK, Chen ISN, Leung CH. Xtep: Winning young Chinese consumers in less developed cities Asian Case Research Journal. 18: 81-114. DOI: 10.1142/S0218927514500047  0.025
2013 Liu SC, Chien KL, Wang CH, Chen WC, Leung CH. Efficacy and safety of adding pioglitazone or sitagliptin to patients with type 2 diabetes insufficiently controlled with metformin and a sulfonylurea. Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 19: 980-8. PMID 23807528 DOI: 10.4158/EP13148.OR  0.024
2011 Leung CH, Wang L, Fu YY, Yuen W, Caldarone CA. Transient mitochondrial permeability transition pore opening after neonatal cardioplegic arrest. The Journal of Thoracic and Cardiovascular Surgery. 141: 975-82. PMID 20884027 DOI: 10.1016/j.jtcvs.2010.08.030  0.024
2007 Leung CH, Ma WK, Poon WS. Bryan artificial cervical disc arthroplasty in a patient with Klippel-Feil syndrome. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. 13: 399-402. PMID 17914149  0.023
2015 Chien MN, Lee CC, Liu SC, Chen WC, Leung CH, Wang CH. Basal Insulin Initiation in Elderly Patients with Type 2 Diabetes in Taiwan: A Comparison with Younger Patients International Journal of Gerontology. 9: 142-145. DOI: 10.1016/j.ijge.2015.05.016  0.023
2005 Wang MY, Leung CH, Casey AT. Cervical arthroplasty with the Bryan disc. Neurosurgery. 56: 58-65; discussion 58. PMID 15799793  0.022
2013 Han CY, Qian LX, Leung CH, Che CM, Lai PT. A low-frequency noise model with carrier generation-recombination process for pentacene organic thin-film transistor Journal of Applied Physics. 114. DOI: 10.1063/1.4816103  0.021
2014 Li L, Mak KY, Leung CW, Leung CH, Ruotolo A, Chan KY, Chan WK, Pong PWT. Synthesis and morphology control of gold/iron oxide magnetic nanocomposites via a simple aqueous method Ieee Transactions On Magnetics. 50. DOI: 10.1109/TMAG.2013.2274457  0.021
2013 Ma D, He H, Leung K, Chan DS, Leung C. Bioaktive lumineszierende Übergangsmetallkomplexe für biomedizinische Anwendungen Angewandte Chemie. 125: 7820-7837. DOI: 10.1002/Ange.201208414  0.021
1982 Lee HC, Leung CH. Dynamic computed tomography through interpolation. Journal of Computer Assisted Tomography. 6: 134-40. PMID 7068993  0.02
2014 Chan SM, Leung CH. Factor Structure of the Screen for Child Anxiety-Related Emotional Disorders (SCARED) in a Community Sample of Hong Kong Chinese Adolescents. Child Psychiatry and Human Development. PMID 25288523 DOI: 10.1007/s10578-014-0509-8  0.019
1986 Williams RT, Song KS, Faust WL, Leung CH. Off-center self-trapped excitons and creation of lattice defects in alkali halide crystals. Physical Review. B, Condensed Matter. 33: 7232-7240. PMID 9938056  0.019
2015 Han CY, Song JQ, Tang WM, Leung CH, Lai PT. High-performance organic thin-film transistor by using LaNbO as gate dielectric Applied Physics Letters. 107. DOI: 10.1063/1.4927098  0.018
2001 Leung CH, Poon WS, Yu LM. Is retrospective study reliable in genetic studies? Stroke; a Journal of Cerebral Circulation. 32: 2441. PMID 11588342  0.018
2015 Au DW, Tsang HW, Ling PP, Leung CH, Ip PK, Cheung WM. Effects of acupressure on anxiety: a systematic review and meta-analysis. Acupuncture in Medicine : Journal of the British Medical Acupuncture Society. PMID 26002571 DOI: 10.1136/acupmed-2014-010720  0.018
2013 Han CY, Tang WM, Leung CH, Che CM, Lai PT. High-performance pentacene thin-film transistor with high-κ HfLaON as gate dielectric Ieee Electron Device Letters. 34: 1397-1399. DOI: 10.1109/LED.2013.2281661  0.018
2003 Leung CH, Poon WS, Yu LM. The ISAT trial. Lancet. 361: 430-1; author reply . PMID 12573403  0.018
2014 Leung CH, Gomersall CD. Middle East respiratory syndrome. Intensive Care Medicine. 40: 1015-7. PMID 24818865 DOI: 10.1007/s00134-014-3303-y  0.018
2014 Huang XD, Shi RP, Leung CH, Lai PT. Charge-trapping characteristics of BaTiO3 with and without nitridation for nonvolatile memory applications Microelectronics Reliability. 54: 2388-2391. DOI: 10.1016/j.microrel.2014.05.002  0.017
2008 Leung CH, Wang NY, Liu CP, Weng LC, Hsieh FC, Lee CM. Antimicrobial therapy and control of multidrug-resistant Pseudomonas aeruginosa bacteremia in a teaching hospital in Taiwan. Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi. 41: 491-8. PMID 19255693  0.017
2006 Wang CH, Leung CH, Liu SC, Chung CH. Safety and effectiveness of rosiglitazone in type 2 diabetes patients with nonalcoholic Fatty liver disease. Journal of the Formosan Medical Association = Taiwan Yi Zhi. 105: 743-52. PMID 16959622 DOI: 10.1016/S0929-6646(09)60202-3  0.017
2006 Lam W, Park SY, Leung CH, Cheng YC. Apurinic/apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (troxacitabine and beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine analogs (gemcitabine and beta-D-arabinofuranosylcytosine). Molecular Pharmacology. 69: 1607-14. PMID 16481390 DOI: 10.1124/mol.105.021527  0.017
2014 Leung CH, Bourda C, Cui Y, Hu L. Weibull and gamma analysis of contact welding in AgW contacts with different tungsten particle sizes Proceedings of the 5th International Conference On Reliability of Electrical Products and Electrical Contacts, Icrepec 2014. 34-39.  0.016
2013 Shi RP, Huang XD, Leung CH, Lai PT. Charge-trapping characteristics of niobium-doped La2O 3 for nonvolatile memory applications 2013 Ieee International Conference of Electron Devices and Solid-State Circuits, Edssc 2013. DOI: 10.1109/EDSSC.2013.6628190  0.016
2013 Han CY, Qian LX, Leung CH, Che CM, Lai PT. High-performance pentacene thin-film transistor with ZrLaO gate dielectric passivated by fluorine incorporation Organic Electronics: Physics, Materials, Applications. 14: 2973-2979. DOI: 10.1016/j.orgel.2013.08.018  0.016
2015 Shi R, Huang XD, Leung CH, Sin JKO, Lai PT. Nb-doped La2O3 as charge-trapping layer for nonvolatile memory applications Ieee Transactions On Device and Materials Reliability. 15: 123-126. DOI: 10.1109/TDMR.2014.2376514  0.015
2014 Han CY, Tang WM, Leung CH, Che CM, Lai PT. High-mobility pentacene thin-film transistor by using LaxTa (1-x)Oy as gate dielectric Organic Electronics: Physics, Materials, Applications. 15: 2499-2504. DOI: 10.1016/j.orgel.2014.07.016  0.015
2014 Zhang X, Teo WT, Rao W, Ma DL, Leung CH, Chan PWH. Synthesis of highly substituted indene derivatives by Brønsted acid catalyzed Friedel-Crafts reaction of homoallylic alcohols Tetrahedron Letters. 55: 3881-3884. DOI: 10.1016/j.tetlet.2014.05.027  0.014
2014 Qian W, Shan X, Liang H, Huang J, Leung CH. A generalized beta-advection model to improve unusual typhoon track prediction by decomposing total flow into climatic and anomalous flows Journal of Geophysical Research Atmospheres. 119: 1097-1117. DOI: 10.1002/2013JD020902  0.014
2012 Lee F, Leung CH, Huang WC, Cheng SP. Killian-Jamieson diverticulum masquerading as a thyroid mass. Internal Medicine (Tokyo, Japan). 51: 1141-2. PMID 22576405 DOI: JST.JSTAGE/internalmedicine/51.7219  0.013
2013 Leung KC, Leung CH. Dynamic discriminant functions with missing feature values Pattern Recognition Letters. 34: 1548-1556. DOI: 10.1016/j.patrec.2013.06.016  0.013
2010 Li C, Leung C, Lai P, Xu J. Effects of fluorine incorporation on the properties of Ge p-MOS capacitors with HfTiON dielectric Solid-State Electronics. 54: 675-679. DOI: 10.1016/J.SSE.2010.03.002  0.013
2009 Li C, Wang C, Leung C, Lai P, Xu J. A study on fluorine incorporation in Ge p-MOS capacitors with HfTiON dielectric Microelectronic Engineering. 86: 1596-1598. DOI: 10.1016/J.MEE.2009.03.022  0.013
2015 Chan PWH, Teo WT, Koh SWY, Lee BR, Ayers BJ, Ma DL, Leung CH. Silver Triflate Catalyzed Cyclopropyl Carbinol Rearrangement for Benzo[b]oxepine and 2H-Chromene Synthesis European Journal of Organic Chemistry. 2015: 4447-4456. DOI: 10.1002/ejoc.201500374  0.012
2003 Wong GK, Leung CH, Chiu KW, Ma R, Cockram CS, Lam MJ, Poon WS. LINAC radiosurgery in recurrent Cushing's disease after transsphenoidal surgery: a series of 5 cases. Minimally Invasive Neurosurgery : Min. 46: 327-30. PMID 14968397 DOI: 10.1055/s-2003-812497  0.012
2015 Han CY, Leung CH, Lai PT, Tang WM. Pentacene organic thin-film transistor with HfYO gate dielectric made on adhesive vacuum tape Electronics Letters. 51: 644-646. DOI: 10.1049/el.2015.0118  0.011
2015 Leung CH, Lai CL, Yuan TK, Pang WM, Tang JKT, Ho WS, Wong TL. The development of a final year project management system for information technology programmes Communications in Computer and Information Science. 494: 86-97.  0.01
2008 Wong RC, Leung CH. Automatic semantic annotation of real-world web images. Ieee Transactions On Pattern Analysis and Machine Intelligence. 30: 1933-44. PMID 18787242 DOI: 10.1109/TPAMI.2008.125  0.01
2015 Tang K, Lu SY, Ma DL, Leung CH, Lee SS, Lin SW, Wang HMD. A review on common ingredients of periocular cosmetics and their hazards Current Organic Chemistry. 19: 30-38.  0.01
2015 Tang K, Lu SY, Ma DL, Leung CH, Lee SS, Lin SW, Wang HMD. A review on common ingredients of periocular cosmetics and their hazards Current Organic Chemistry. 19: 30-38.  0.01
2014 Cheung RHP, Leung CH. Preschool teachers' perceptions of creative personality important for fostering creativity: Hong Kong perspective Thinking Skills and Creativity. 12: 78-89. DOI: 10.1016/j.tsc.2014.01.001  0.01
2014 Hue MT, Leung CH, Kennedy KJ. Student perception of assessment practices: towards ‘no loser’ classrooms for all students in the ethnic minority schools in Hong Kong Educational Assessment, Evaluation and Accountability. DOI: 10.1007/s11092-014-9205-2  0.01
2014 Han CY, Tang WM, Leung CH, Che CM, Lai PT. High-mobility pentacene OTFT with TaLaO gate dielectric passivated by fluorine plasma Physica Status Solidi - Rapid Research Letters. DOI: 10.1002/pssr.201409261  0.01
2013 Du Y, Lai PT, Leung CH, Pong PW. Design of superparamagnetic nanoparticles for magnetic particle imaging (MPI). International Journal of Molecular Sciences. 14: 18682-710. PMID 24030719 DOI: 10.3390/ijms140918682  0.01
2013 Han CY, Leung CH, Lai PT, Tang WM, Che CM. Effects of fluorine plasma and ammonia annealing on pentacene thin-film transistor with HfTiO as gate dielectric 2013 Ieee International Conference of Electron Devices and Solid-State Circuits, Edssc 2013. DOI: 10.1109/EDSSC.2013.6628118  0.01
2013 Cheung RHP, Leung CH. Preschool Teachers' Beliefs of Creative Pedagogy: Important for Fostering Creativity Creativity Research Journal. 25: 397-407. DOI: 10.1080/10400419.2013.843334  0.01
2013 Leung Ch, Wong BKM, Wong J. Conceptions of learning in pre-service and in-service early childhood education students and the impact of teaching experience Australian Journal of Early Childhood. 38: 57-67.  0.01
2008 Ng WN, Leung CH, Lai PT, Choi HW. Photonic crystal light-emitting diodes fabricated by microsphere lithography. Nanotechnology. 19: 255302. PMID 21828649 DOI: 10.1088/0957-4484/19/25/255302  0.01
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