Year |
Citation |
Score |
2008 |
Bruce LA, Sigman JA, Randall D, Rodriguez S, Song MM, Dai Y, Elmore DE, Pabon A, Glucksman MJ, Wolfson AJ. Hydrogen bond residue positioning in the 599-611 loop of thimet oligopeptidase is required for substrate selection. The Febs Journal. 275: 5607-17. PMID 18959747 DOI: 10.1111/J.1742-4658.2008.06685.X |
0.504 |
|
2005 |
Sigman JA, Patwa TH, Tablante AV, Joseph CD, Glucksman MJ, Wolfson AJ. Flexibility in substrate recognition by thimet oligopeptidase as revealed by denaturation studies. The Biochemical Journal. 388: 255-61. PMID 15647004 DOI: 10.1042/Bj20041481 |
0.52 |
|
2003 |
Sigman JA, Sharky ML, Walsh ST, Pabon A, Glucksman MJ, Wolfson AJ. Involvement of surface cysteines in activity and multimer formation of thimet oligopeptidase. Protein Engineering. 16: 623-8. PMID 12968080 DOI: 10.1093/Protein/Gzg073 |
0.517 |
|
2003 |
Sigman JA, Edwards SR, Pabon A, Glucksman MJ, Wolfson AJ. pH dependence studies provide insight into the structure and mechanism of thimet oligopeptidase (EC 3.4.24.15). Febs Letters. 545: 224-8. PMID 12804780 DOI: 10.1016/S0014-5793(03)00548-9 |
0.504 |
|
2003 |
Sigman JA, Kim HK, Zhao X, Carey JR, Lu Y. The role of copper and protons in heme-copper oxidases: kinetic study of an engineered heme-copper center in myoglobin. Proceedings of the National Academy of Sciences of the United States of America. 100: 3629-34. PMID 12655052 DOI: 10.1073/pnas.0737308100 |
0.621 |
|
2003 |
Perera R, Sono M, Sigman JA, Pfister TD, Lu Y, Dawson JH. Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction. Proceedings of the National Academy of Sciences of the United States of America. 100: 3641-6. PMID 12655049 DOI: 10.1073/Pnas.0737142100 |
0.594 |
|
2003 |
Lu Y, Sigman JA, Kim HK, Zhao X, Carey JR. The role of copper and protons in heme-copper oxidases: Kinetic study of an engineered heme-copper center in myoglobin Journal of Inorganic Biochemistry. 96: 183. DOI: 10.1016/S0162-0134(03)80696-7 |
0.449 |
|
2001 |
Sigman JA, Wang X, Lu Y. Coupled oxidation of heme by myoglobin is mediated by exogenous peroxide. Journal of the American Chemical Society. 123: 6945-6. PMID 11448209 DOI: 10.1021/Ja015776U |
0.337 |
|
2000 |
Sigman JA, Kwok BC, Lu Y. From myoglobin to heme-copper oxidase: Design and engineering of a Cu(B) center into sperm whale myoglobin Journal of the American Chemical Society. 122: 8192-8196. DOI: 10.1021/Ja0015343 |
0.564 |
|
1999 |
Sigman JA, Pond AE, Dawson JH, Lu Y. Engineering cytochrome c peroxidase into cytochrome P450: a proximal effect on heme-thiolate ligation. Biochemistry. 38: 11122-9. PMID 10460168 DOI: 10.1021/Bi990815O |
0.489 |
|
1999 |
Sigman JA, Kwok BC, Gengenbach A, Lu Y. Design and creation of a Cu(II)-binding site in cytochrome c peroxidase that mimics the Cu(B)-heme center in terminal oxidases [5] Journal of the American Chemical Society. 121: 8949-8950. DOI: 10.1021/Ja991195H |
0.531 |
|
1997 |
Yeung BK, Wang X, Sigman JA, Petillo PA, Lu Y. Construction and characterization of a manganese-binding site in cytochrome c peroxidase: towards a novel manganese peroxidase. Chemistry & Biology. 4: 215-21. PMID 9115415 DOI: 10.1016/S1074-5521(97)90291-X |
0.509 |
|
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