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Ganesh Venkataraman - Publications

Affiliations: 
1993 Massachusetts Institute of Technology, Cambridge, MA, United States 
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Shriver Z, Capila I, Venkataraman G, Sasisekharan R. Heparin and heparan sulfate: analyzing structure and microheterogeneity. Handbook of Experimental Pharmacology. 159-76. PMID 22566225 DOI: 10.1007/978-3-642-23056-1_8  0.323
2012 Schultes BC, Chu CL, Long A, D'Alessandro J, Honan CM, Kishimoto TK, Venkataraman G. Abstract 2336: M402, a heparan sulfate mimetic, inhibits tumor revascularization and invasiveness after high-dose taxane treatment in a mouse breast cancer model Cancer Research. 72: 2336-2336. DOI: 10.1158/1538-7445.Am2012-2336  0.305
2011 Zhou H, Roy S, Cochran E, Zouaoui R, Chu CL, Duffner J, Zhao G, Smith S, Galcheva-Gargova Z, Karlgren J, Dussault N, Kwan RY, Moy E, Barnes M, Long A, ... ... Venkataraman G, et al. M402, a novel heparan sulfate mimetic, targets multiple pathways implicated in tumor progression and metastasis. Plos One. 6: e21106. PMID 21698156 DOI: 10.1371/Journal.Pone.0021106  0.316
2011 Roy S, Lai H, Zouaoui R, Duffner J, Zhou H, P Jayaraman L, Zhao G, Ganguly T, Kishimoto TK, Venkataraman G. Bioactivity screening of partially desulfated low-molecular-weight heparins: a structure/activity relationship study. Glycobiology. 21: 1194-205. PMID 21515908 DOI: 10.1093/Glycob/Cwr053  0.377
2010 Beccati D, Roy S, Yu F, Gunay NS, Capila I, Lech M, Linhardt RJ, Venkataraman G. Identification of a novel structure in heparin generated by potassium permanganate oxidation. Carbohydrate Polymers. 82: 699-705. PMID 25147414 DOI: 10.1016/J.Carbpol.2010.05.038  0.306
2010 Zhou H, Roy S, Cochran E, Zouaoui R, Karlgren J, Dussault N, Kwan RY, Duffner J, Zhao G, Smith S, Galcheva-Gargova Z, Moy E, Barnes M, Honan C, Chu CL, ... ... Venkataraman G, et al. Abstract 2269: M402 - A novel heparan sulfate proteoglycan mimetic targeting tumor-host interactions Cancer Research. 70: 2269-2269. DOI: 10.1158/1538-7445.Am10-2269  0.305
2008 Galcheva-Gargova Z, Zhidkova N, Geisler S, Ozug J, Wudyka S, Gunay NS, Qi YW, Shriver Z, Venkataraman G. Overexpression of Merlin in B16F10 mouse melanoma cells reduces their metastatic activity: role of the cell surface heparan sulfate glycosaminoglycans. International Journal of Oncology. 32: 1237-43. PMID 18497985 DOI: 10.3892/Ijo_32_6_1237  0.334
2007 Yang Y, MacLeod V, Dai Y, Khotskaya-Sample Y, Shriver Z, Venkataraman G, Sasisekharan R, Naggi A, Torri G, Casu B, Vlodavsky I, Suva LJ, Epstein J, Yaccoby S, Shaughnessy JD, et al. The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy. Blood. 110: 2041-8. PMID 17536013 DOI: 10.1182/Blood-2007-04-082495  0.342
2006 Shaya D, Tocilj A, Li Y, Myette J, Venkataraman G, Sasisekharan R, Cygler M. Crystal structure of heparinase II from Pedobacter heparinus and its complex with a disaccharide product. The Journal of Biological Chemistry. 281: 15525-35. PMID 16565082 DOI: 10.1074/Jbc.M512055200  0.307
2005 Dai Y, Yang Y, MacLeod V, Yue X, Rapraeger AC, Shriver Z, Venkataraman G, Sasisekharan R, Sanderson RD. HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo. The Journal of Biological Chemistry. 280: 40066-73. PMID 16192265 DOI: 10.1074/Jbc.M508136200  0.347
2005 Dai Y, Yang Y, MacLeod V, Yue X, Rapraeger AC, Shriver Z, Venkataraman G, Sasisekharan R, Sanderson RD. Extracellular Endosulfatases (Sulfs) Inhibit Myeloma Tumor Growth In Vivo. Blood. 106: 3386-3386. DOI: 10.1182/Blood.V106.11.3386.3386  0.353
2004 Berry D, Shriver Z, Venkataraman G, Sasisekharan R. Quantitative assessment of FGF regulation by cell surface heparan sulfates. Biochemical and Biophysical Research Communications. 314: 994-1000. PMID 14751231 DOI: 10.1016/J.Bbrc.2003.12.188  0.359
2003 Berry D, Shriver Z, Natke B, Kwan CP, Venkataraman G, Sasisekharan R. Heparan sulphate glycosaminoglycans derived from endothelial cells and smooth muscle cells differentially modulate fibroblast growth factor-2 biological activity through fibroblast growth factor receptor-1. The Biochemical Journal. 373: 241-9. PMID 12659634 DOI: 10.1042/Bj20021760  0.354
2003 Raman R, Venkataraman G, Ernst S, Sasisekharan V, Sasisekharan R. Structural specificity of heparin binding in the fibroblast growth factor family of proteins. Proceedings of the National Academy of Sciences of the United States of America. 100: 2357-62. PMID 12604799 DOI: 10.1073/Pnas.0437842100  0.352
2003 Sundaram M, Qi Y, Shriver Z, Liu D, Zhao G, Venkataraman G, Langer R, Sasisekharan R. Rational design of low-molecular weight heparins with improved in vivo activity. Proceedings of the National Academy of Sciences of the United States of America. 100: 651-6. PMID 12525684 DOI: 10.1073/Pnas.252643299  0.327
2003 Myette JR, Shriver Z, Claycamp C, McLean MW, Venkataraman G, Sasisekharan R. The heparin/heparan sulfate 2-O-sulfatase from Flavobacterium heparinum. Molecular cloning, recombinant expression, and biochemical characterization. The Journal of Biological Chemistry. 278: 12157-66. PMID 12519775 DOI: 10.1074/Jbc.M211420200  0.34
2003 Raman R, Myette JR, Shriver Z, Pojasek K, Venkataraman G, Sasisekharan R. The heparin/heparan sulfate 2-O-sulfatase from Flavobacterium heparinum. A structural and biochemical study of the enzyme active site and saccharide substrate specificity. The Journal of Biological Chemistry. 278: 12167-74. PMID 12519774 DOI: 10.1074/Jbc.M211425200  0.339
2002 Guerrini M, Raman R, Venkataraman G, Torri G, Sasisekharan R, Casu B. A novel computational approach to integrate NMR spectroscopy and capillary electrophoresis for structure assignment of heparin and heparan sulfate oligosaccharides. Glycobiology. 12: 713-9. PMID 12460939 DOI: 10.1093/Glycob/Cwf084  0.349
2002 Sasisekharan R, Shriver Z, Venkataraman G, Narayanasami U. Roles of heparan-sulphate glycosaminoglycans in cancer. Nature Reviews. Cancer. 2: 521-8. PMID 12094238 DOI: 10.1038/Nrc842  0.33
2002 Pojasek K, Raman R, Kiley P, Venkataraman G, Sasisekharan R. Biochemical characterization of the chondroitinase B active site. The Journal of Biological Chemistry. 277: 31179-86. PMID 12063249 DOI: 10.1074/Jbc.M201552200  0.318
2002 Myette JR, Shriver Z, Kiziltepe T, McLean MW, Venkataraman G, Sasisekharan R. Molecular cloning of the heparin/heparan sulfate delta 4,5 unsaturated glycuronidase from Flavobacterium heparinum, its recombinant expression in Escherichia coli, and biochemical determination of its unique substrate specificity. Biochemistry. 41: 7424-34. PMID 12044176 DOI: 10.1021/Bi012147O  0.308
2002 Liu D, Shriver Z, Qi Y, Venkataraman G, Sasisekharan R. Dynamic regulation of tumor growth and metastasis by heparan sulfate glycosaminoglycans. Seminars in Thrombosis and Hemostasis. 28: 67-78. PMID 11885027 DOI: 10.1055/S-2002-20565  0.35
2002 Raman R, Myette J, Venkataraman G, Sasisekharan V, Sasisekharan R. Identification of structural motifs and amino acids within the structure of human heparan sulfate 3-O-sulfotransferase that mediate enzymatic function. Biochemical and Biophysical Research Communications. 290: 1214-9. PMID 11811992 DOI: 10.1006/Bbrc.2001.6267  0.321
2002 Myette JR, Shriver Z, Liu J, Venkataraman G, Rosenberg R, Sasisekharan R. Expression in Escherichia coli, purification and kinetic characterization of human heparan sulfate 3-O-sulfotransferase-1. Biochemical and Biophysical Research Communications. 290: 1206-13. PMID 11811991 DOI: 10.1006/Bbrc.2001.6268  0.33
2002 Liu D, Shriver Z, Venkataraman G, El Shabrawi Y, Sasisekharan R. Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 99: 568-73. PMID 11805315 DOI: 10.1073/Pnas.012578299  0.369
2001 Berry D, Kwan CP, Shriver Z, Venkataraman G, Sasisekharan R. Distinct heparan sulfate glycosaminoglycans are responsible for mediating fibroblast growth factor-2 biological activity through different fibroblast growth factor receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1422-4. PMID 11387244 DOI: 10.1096/Fj.00-0661Fje  0.377
2001 Karumanchi SA, Jha V, Ramchandran R, Karihaloo A, Tsiokas L, Chan B, Dhanabal M, Hanai JI, Venkataraman G, Shriver Z, Keiser N, Kalluri R, Zeng H, Mukhopadhyay D, Chen RL, et al. Cell surface glypicans are low-affinity endostatin receptors. Molecular Cell. 7: 811-22. PMID 11336704 DOI: 10.1016/S1097-2765(01)00225-8  0.333
2000 Sasisekharan R, Venkataraman G. Heparin and heparan sulfate: biosynthesis, structure and function Current Opinion in Chemical Biology. 4: 626-631. PMID 11102866 DOI: 10.1016/S1367-5931(00)00145-9  0.337
2000 Shriver Z, Sundaram M, Venkataraman G, Fareed J, Linhardt R, Biemann K, Sasisekharan R. Cleavage of the antithrombin III binding site in heparin by heparinases and its implication in the generation of low molecular weight heparin. Proceedings of the National Academy of Sciences of the United States of America. 97: 10365-70. PMID 10984532 DOI: 10.1073/Pnas.97.19.10365  0.31
2000 Shriver Z, Raman R, Venkataraman G, Drummond K, Turnbull J, Toida T, Linhardt R, Biemann K, Sasisekharan R. Sequencing of 3-O sulfate containing heparin decasaccharides with a partial antithrombin III binding site. Proceedings of the National Academy of Sciences of the United States of America. 97: 10359-64. PMID 10984531 DOI: 10.1073/Pnas.97.19.10359  0.34
1999 Natke B, Venkataraman G, Nugent MA, Sasisekharan R. Heparinase treatment of bovine smooth muscle cells inhibits fibroblast growth factor-2 binding to fibroblast growth factor receptor but not FGF-2 mediated cellular proliferation. Angiogenesis. 3: 249-57. PMID 14517424 DOI: 10.1023/A:1009008824246  0.351
1999 Padera R, Venkataraman G, Berry D, Godavarti R, Sasisekharan R. FGF-2/fibroblast growth factor receptor/heparin-like glycosaminoglycan interactions: a compensation model for FGF-2 signaling. The Faseb Journal. 13: 1677-1687. PMID 10506571 DOI: 10.1096/Fasebj.13.13.1677  0.319
1999 Venkataraman G, Raman R, Sasisekharan V, Sasisekharan R. Molecular Characteristics Of Fibroblast Growth Factor-Fibroblast Growth Factor Receptor-Heparin-Like Glycosaminoglycan Complex Proceedings of the National Academy of Sciences of the United States of America. 96: 3658-3663. PMID 10097093 DOI: 10.1073/Pnas.96.7.3658  0.341
1999 Venkataraman G, Shriver Z, Davis JC, Sasisekharan R. Fibroblast growth factors 1 and 2 are distinct in oligomerization in the presence of heparin-like glycosaminoglycans Proceedings of the National Academy of Sciences of the United States of America. 96: 1892-1897. PMID 10051565 DOI: 10.1073/Pnas.96.5.1892  0.345
1999 Davis JC, Venkataraman G, Shriver Z, Raj PA, Sasisekharan R. Oligomeric self-association of basic fibroblast growth factor in the absence of heparin-like glycosaminoglycans. Biochemical Journal. 341: 613-620. DOI: 10.1042/Bj3410613  0.321
1997 Sasisekharan R, Ernst S, Venkataraman G. On the regulation of fibroblast growth factor activity by heparin-like glycosaminoglycans. Angiogenesis. 1: 45-54. PMID 14517393 DOI: 10.1023/A:1018318914258  0.362
1996 Venkataraman G, Sasisekharan V, Herr AB, Ornitz DM, Waksman G, Cooney CL, Langer R, Sasisekharan R. Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation Proceedings of the National Academy of Sciences of the United States of America. 93: 845-850. PMID 8570646 DOI: 10.1073/Pnas.93.2.845  0.336
1995 Sasisekharan R, Leckband D, Godavarti R, Venkataraman G, Cooney CL, Langer R. Heparinase I from Flavobacterium heparinum: the role of the cysteine residue in catalysis as probed by chemical modification and site-directed mutagenesis. Biochemistry. 34: 14441-8. PMID 7578049 DOI: 10.1021/Bi00044A022  0.307
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