David Calkins - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Risner ML, Pasini S, McGrady NR, Calkins DJ. Bax Contributes to Retinal Ganglion Cell Dendritic Degeneration During Glaucoma. Molecular Neurobiology. PMID 34984584 DOI: 10.1007/s12035-021-02675-5  0.52
2021 McGrady NR, Pasini S, Baratta RO, Del Buono BJ, Schlumpf E, Calkins DJ. Restoring the Extracellular Matrix: A Neuroprotective Role for Collagen Mimetic Peptides in Experimental Glaucoma. Frontiers in Pharmacology. 12: 764709. PMID 34795592 DOI: 10.3389/fphar.2021.764709  0.558
2021 Boal AM, Risner ML, Cooper ML, Wareham LK, Calkins DJ. Astrocyte Networks as Therapeutic Targets in Glaucomatous Neurodegeneration. Cells. 10. PMID 34199470 DOI: 10.3390/cells10061368  0.683
2021 Risner ML, Pasini S, McGrady NR, D'Alessandro KB, Yao V, Cooper ML, Calkins DJ. Neuroprotection by Wld depends on retinal ganglion cell type and age in glaucoma. Molecular Neurodegeneration. 16: 36. PMID 34090501 DOI: 10.1186/s13024-021-00459-y  0.785
2021 Al Hussein Al Awamlh S, Wareham LK, Risner ML, Calkins DJ. Insulin Signaling as a Therapeutic Target in Glaucomatous Neurodegeneration. International Journal of Molecular Sciences. 22. PMID 33925119 DOI: 10.3390/ijms22094672  0.328
2021 Calkins DJ. Adaptive responses to neurodegenerative stress in glaucoma. Progress in Retinal and Eye Research. 100953. PMID 33640464 DOI: 10.1016/j.preteyeres.2021.100953  0.57
2021 Naguib S, Backstrom JR, Gil M, Calkins DJ, Rex TS. Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension. Redox Biology. 101883. PMID 33579667 DOI: 10.1016/j.redox.2021.101883  0.405
2020 Risner ML, McGrady NR, Boal AM, Pasini S, Calkins DJ. TRPV1 Supports Axogenic Enhanced Excitability in Response to Neurodegenerative Stress. Frontiers in Cellular Neuroscience. 14: 603419. PMID 33505248 DOI: 10.3389/fncel.2020.603419  0.431
2020 Wareham LK, Risner ML, Calkins DJ. Protect, Repair, and Regenerate: Towards Restoring Vision in Glaucoma. Current Ophthalmology Reports. 8: 301-310. PMID 33269115 DOI: 10.1007/s40135-020-00259-5  0.356
2020 Cooper ML, Pasini S, Lambert WS, D'Alessandro KB, Yao V, Risner ML, Calkins DJ. Redistribution of metabolic resources through astrocyte networks mitigates neurodegenerative stress. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690710 DOI: 10.1073/Pnas.2009425117  0.725
2020 Wareham LK, Calkins DJ. The Neurovascular Unit in Glaucomatous Neurodegeneration. Frontiers in Cell and Developmental Biology. 8: 452. PMID 32656207 DOI: 10.3389/fcell.2020.00452  0.529
2020 Lambert WS, Pasini S, Collyer JW, Formichella CR, Ghose P, Carlson BJ, Calkins DJ. Of Mice and Monkeys: Neuroprotective Efficacy of the p38 Inhibitor BIRB 796 Depends on Model Duration in Experimental Glaucoma. Scientific Reports. 10: 8535. PMID 32444682 DOI: 10.1038/s41598-020-65374-6  0.511
2020 McGrady NR, Risner ML, Vest V, Calkins DJ. TRPV1 Tunes Optic Nerve Axon Excitability in Glaucoma. Frontiers in Physiology. 11: 249. PMID 32273850 DOI: 10.3389/fphys.2020.00249  0.527
2019 Risner ML, McGrady NR, Pasini S, Lambert WS, Calkins DJ. Elevated ocular pressure reduces voltage-gated sodium channel NaV1.2 protein expression in retinal ganglion cell axons. Experimental Eye Research. 107873. PMID 31734278 DOI: 10.1016/j.exer.2019.107873  0.45
2019 Lambert WS, Carlson BJ, Ghose P, Vest VD, Yao V, Calkins DJ. Towards A Microbead Occlusion Model of Glaucoma for a Non-Human Primate. Scientific Reports. 9: 11572. PMID 31399621 DOI: 10.1038/s41598-019-48054-y  0.525
2019 Bernardo-Colón A, Vest V, Cooper ML, Naguib SA, Calkins DJ, Rex TS. Progression and Pathology of Traumatic Optic Neuropathy From Repeated Primary Blast Exposure. Frontiers in Neuroscience. 13: 719. PMID 31354422 DOI: 10.3389/Fnins.2019.00719  0.776
2018 Laughter MR, Bardill JR, Ammar DA, Pena B, Calkins DJ, Park D. Injectable Neurotrophic Factor Delivery System Supporting Retinal Ganglion Cell Survival and Regeneration Following Optic Nerve Crush. Acs Biomaterials Science & Engineering. 4: 3374-3383. PMID 31431919 DOI: 10.1021/Acsbiomaterials.8B00803  0.509
2018 Bernardo-Colon A, Vest V, Clark A, Cooper ML, Calkins DJ, Harrison FE, Rex TS. Antioxidants prevent inflammation and preserve the optic projection and visual function in experimental neurotrauma. Cell Death & Disease. 9: 1097. PMID 30367086 DOI: 10.1038/S41419-018-1061-4  0.707
2018 Cooper ML, Collyer JW, Calkins DJ. Astrocyte remodeling without gliosis precedes optic nerve Axonopathy. Acta Neuropathologica Communications. 6: 38. PMID 29747701 DOI: 10.1186/S40478-018-0542-0  0.783
2018 Risner ML, Pasini S, Cooper ML, Lambert WS, Calkins DJ. Axogenic mechanism enhances retinal ganglion cell excitability during early progression in glaucoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 29463759 DOI: 10.1073/Pnas.1714888115  0.771
2017 Lambert WS, Carlson BJ, Formichella CR, Sappington RM, Ahlem C, Calkins DJ. Oral Delivery of a Synthetic Sterol Reduces Axonopathy and Inflammation in a Rodent Model of Glaucoma. Frontiers in Neuroscience. 11: 45. PMID 28223915 DOI: 10.3389/Fnins.2017.00045  0.533
2017 Calkins DJ, Pekny M, Cooper ML, Benowitz L. The challenge of regenerative therapies for the optic nerve in glaucoma. Experimental Eye Research. PMID 28153739 DOI: 10.1016/J.Exer.2017.01.007  0.776
2016 Bond WS, Hines-Beard J, GoldenMerry YL, Davis M, Farooque A, Sappington RM, Calkins DJ, Rex TS. Virus-mediated EpoR76E Therapy Slows Optic Nerve Axonopathy in Experimental Glaucoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 24: 230-239. PMID 28135578 DOI: 10.1038/mt.2015.198  0.368
2016 Breen KT, Anderson SR, Steele MR, Calkins DJ, Bosco A, Vetter ML. Loss of Fractalkine Signaling Exacerbates Axon Transport Dysfunction in a Chronic Model of Glaucoma. Frontiers in Neuroscience. 10: 526. PMID 27932942 DOI: 10.3389/fnins.2016.00526  0.512
2016 Bosco A, Breen KT, Anderson SR, Steele MR, Calkins DJ, Vetter ML. Glial coverage in the optic nerve expands in proportion to optic axon loss in chronic mouse glaucoma. Experimental Eye Research. PMID 26851485 DOI: 10.1016/j.exer.2016.01.014  0.575
2015 Cooper ML, Crish SD, Inman DM, Horner PJ, Calkins DJ. Early Astrocyte Redistribution in the Optic Nerve Precedes Axonopathy in the DBA/2J Mouse Model of Glaucoma. Experimental Eye Research. PMID 26646560 DOI: 10.1016/J.Exer.2015.11.016  0.774
2015 Bond WS, Hines-Beard JB, GoldenMerry YL, Davis M, Farooque A, Sappington RM, Calkins DJ, Rex TS. Virus-mediated EpoR76E therapy slows optic nerve axonopathy in experimental glaucoma. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 26502777 DOI: 10.1038/Mt.2015.198  0.368
2015 Sappington RM, Sidorova T, Ward NJ, Chakravarthy R, Ho KW, Calkins DJ. Activation of transient receptor potential vanilloid-1 (TRPV1) influences how retinal ganglion cell neurons respond to pressure-related stress. Channels (Austin, Tex.). 9: 102-13. PMID 25713995 DOI: 10.1080/19336950.2015.1009272  0.304
2014 Weitlauf C, Ward NJ, Lambert WS, Sidorova TN, Ho KW, Sappington RM, Calkins DJ. Short-term increases in transient receptor potential vanilloid-1 mediate stress-induced enhancement of neuronal excitation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15369-81. PMID 25392504 DOI: 10.1523/Jneurosci.3424-14.2014  0.451
2014 Ward NJ, Ho KW, Lambert WS, Weitlauf C, Calkins DJ. Absence of transient receptor potential vanilloid-1 accelerates stress-induced axonopathy in the optic projection. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 3161-70. PMID 24573275 DOI: 10.1523/Jneurosci.4089-13.2014  0.499
2013 Dapper JD, Crish SD, Pang IH, Calkins DJ. Proximal inhibition of p38 MAPK stress signaling prevents distal axonopathy. Neurobiology of Disease. 59: 26-37. PMID 23859799 DOI: 10.1016/J.Nbd.2013.07.001  0.763
2013 Inman DM, Lambert WS, Calkins DJ, Horner PJ. α-Lipoic acid antioxidant treatment limits glaucoma-related retinal ganglion cell death and dysfunction. Plos One. 8: e65389. PMID 23755225 DOI: 10.1371/Journal.Pone.0065389  0.332
2013 Crish SD, Dapper JD, MacNamee SE, Balaram P, Sidorova TN, Lambert WS, Calkins DJ. Failure of axonal transport induces a spatially coincident increase in astrocyte BDNF prior to synapse loss in a central target. Neuroscience. 229: 55-70. PMID 23159315 DOI: 10.1016/J.Neuroscience.2012.10.069  0.742
2012 Bosco A, Crish SD, Steele MR, Romero CO, Inman DM, Horner PJ, Calkins DJ, Vetter ML. Early reduction of microglia activation by irradiation in a model of chronic glaucoma. Plos One. 7: e43602. PMID 22952717 DOI: 10.1371/Journal.Pone.0043602  0.431
2012 Calkins DJ. Critical pathogenic events underlying progression of neurodegeneration in glaucoma. Progress in Retinal and Eye Research. 31: 702-19. PMID 22871543 DOI: 10.1016/j.preteyeres.2012.07.001  0.615
2012 Calkins DJ, Horner PJ. The cell and molecular biology of glaucoma: axonopathy and the brain. Investigative Ophthalmology & Visual Science. 53: 2482-4. PMID 22562846 DOI: 10.1167/Iovs.12-9483I  0.505
2011 Lambert WS, Ruiz L, Crish SD, Wheeler LA, Calkins DJ. Brimonidine prevents axonal and somatic degeneration of retinal ganglion cell neurons. Molecular Neurodegeneration. 6: 4. PMID 21232114 DOI: 10.1186/1750-1326-6-4  0.549
2011 Chen H, Wei X, Cho KS, Chen G, Sappington R, Calkins DJ, Chen DF. Optic neuropathy due to microbead-induced elevated intraocular pressure in the mouse. Investigative Ophthalmology & Visual Science. 52: 36-44. PMID 20702815 DOI: 10.1167/Iovs.09-5115  0.334
2010 Baltan S, Inman DM, Danilov CA, Morrison RS, Calkins DJ, Horner PJ. Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5644-52. PMID 20410117 DOI: 10.1523/Jneurosci.5956-09.2010  0.539
2010 Crish SD, Sappington RM, Inman DM, Horner PJ, Calkins DJ. Distal axonopathy with structural persistence in glaucomatous neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 107: 5196-201. PMID 20194762 DOI: 10.1073/Pnas.0913141107  0.574
2008 Wax MB, Tezel G, Yang J, Peng G, Patil RV, Agarwal N, Sappington RM, Calkins DJ. Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12085-96. PMID 19005073 DOI: 10.1523/Jneurosci.3200-08.2008  0.407
2008 Calkins DJ, Horner PJ, Roberts R, Gradianu M, Berkowitz BA. Manganese-enhanced MRI of the DBA/2J mouse model of hereditary glaucoma. Investigative Ophthalmology & Visual Science. 49: 5083-8. PMID 18552381 DOI: 10.1167/Iovs.08-2205  0.37
2008 Bosco A, Inman DM, Steele MR, Wu G, Soto I, Marsh-Armstrong N, Hubbard WC, Calkins DJ, Horner PJ, Vetter ML. Reduced retina microglial activation and improved optic nerve integrity with minocycline treatment in the DBA/2J mouse model of glaucoma. Investigative Ophthalmology & Visual Science. 49: 1437-46. PMID 18385061 DOI: 10.1167/Iovs.07-1337  0.58
2008 Buckingham BP, Inman DM, Lambert W, Oglesby E, Calkins DJ, Steele MR, Vetter ML, Marsh-Armstrong N, Horner PJ. Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 2735-44. PMID 18337403 DOI: 10.1523/Jneurosci.4443-07.2008  0.53
2006 Sappington RM, Chan M, Calkins DJ. Interleukin-6 protects retinal ganglion cells from pressure-induced death. Investigative Ophthalmology & Visual Science. 47: 2932-42. PMID 16799036 DOI: 10.1167/Iovs.05-1407  0.303
2006 Inman DM, Sappington RM, Horner PJ, Calkins DJ. Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma. Investigative Ophthalmology & Visual Science. 47: 986-96. PMID 16505033 DOI: 10.1167/Iovs.05-0925  0.462
2005 Calkins DJ, Sappington RM, Hendry SH. Morphological identification of ganglion cells expressing the alpha subunit of type II calmodulin-dependent protein kinase in the macaque retina. The Journal of Comparative Neurology. 481: 194-209. PMID 15562509 DOI: 10.1002/Cne.20368  0.43
2003 Sappington RM, Pearce DA, Calkins DJ. Optic nerve degeneration in a murine model of juvenile ceroid lipofuscinosis. Investigative Ophthalmology & Visual Science. 44: 3725-31. PMID 12939285 DOI: 10.1167/Iovs.03-0039  0.359
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