Fernanda Laezza - Publications

Affiliations: 
2001 Emory University, Atlanta, GA 

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Dvorak NM, Wadsworth PA, Wang P, Chen H, Zhou J, Laezza F. Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics. Molecules (Basel, Switzerland). 25. PMID 32722255 DOI: 10.3390/molecules25153365  0.32
2020 Singh AK, Wadsworth PA, Tapia CM, Aceto G, Ali SR, Chen H, D'Ascenzo M, Zhou J, Laezza F. Mapping of the FGF14:Nav1.6 complex interface reveals FLPK as a functionally active peptide modulating excitability. Physiological Reports. 8: e14505. PMID 32671946 DOI: 10.14814/phy2.14505  0.92
2020 Wadsworth PA, Singh AK, Nguyen N, Dvorak NM, Tapia CM, Russell WK, Stephan C, Laezza F. JAK2 regulates Nav1.6 channel function via FGF14 phosphorylation. Biochimica Et Biophysica Acta. Molecular Cell Research. 118786. PMID 32599005 DOI: 10.1016/j.bbamcr.2020.118786  0.4
2020 Tapia C, Folorunso O, Singh AK, McDonough K, Laezza F. Effects of Deltamethrin Acute Exposure on Nav1.6 channels and Medium Spiny Neurons of the Nucleus Accumbens. Toxicology. 152488. PMID 32387285 DOI: 10.1016/j.tox.2020.152488  0.4
2020 Aceto G, Colussi C, Leone L, Fusco S, Rinaudo M, Scala F, Green TA, Laezza F, D'Ascenzo M, Grassi C. Chronic mild stress alters synaptic plasticity in the nucleus accumbens through GSK3β-dependent modulation of Kv4.2 channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 32209671 DOI: 10.1073/pnas.1917423117  0.32
2019 Wadsworth PA, Folorunso O, Nguyen N, Singh AK, D'Amico D, Powell RT, Brunell D, Allen J, Stephan C, Laezza F. High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na channel complex. Scientific Reports. 9: 16890. PMID 31729429 DOI: 10.1038/s41598-019-53110-8  0.4
2019 Alshammari TK, Alghamdi H, Green TA, Niazy A, Alkahdar L, Alrasheed N, Alhosaini K, Alswayyed M, Elango R, Laezza F, Alshammari MA, Yacoub H. Assessing the role of toll-like receptor in isolated, standard and enriched housing conditions. Plos One. 14: e0222818. PMID 31647818 DOI: 10.1371/journal.pone.0222818  0.68
2019 Aceto G, Re A, Mattera A, Leone L, Colussi C, Rinaudo M, Scala F, Gironi K, Barbati SA, Fusco S, Green T, Laezza F, D'Ascenzo M, Grassi C. Corrigendum: GSK3β Modulates Timing-Dependent Long-Term Depression Through Direct Phosphorylation of Kv4.2 Channels. Cerebral Cortex (New York, N.Y. : 1991). PMID 30806456 DOI: 10.1093/cercor/bhz028  0.32
2019 Sowers ML, Re JD, Wadsworth PA, Shavkunov AS, Lichti C, Zhang K, Laezza F. Sex-Specific Proteomic Changes Induced by Genetic Deletion of Fibroblast Growth Factor 14 (FGF14), a Regulator of Neuronal Ion Channels. Proteomes. 7. PMID 30678040 DOI: 10.3390/proteomes7010005  0.92
2018 Liu Z, Wadsworth P, Singh AK, Chen H, Wang P, Folorunso O, Scaduto P, Ali SR, Laezza F, Zhou J. Identification of peptidomimetics as novel chemical probes modulating fibroblast growth factor 14 (FGF14) and voltage-gated sodium channel 1.6 (Nav1.6) protein-protein interactions. Bioorganic & Medicinal Chemistry Letters. PMID 30587448 DOI: 10.1016/j.bmcl.2018.12.031  0.92
2018 Aceto G, Re A, Mattera A, Leone L, Colussi C, Rinaudo M, Scala F, Gironi K, Barbati SA, Fusco S, Green T, Laezza F, D'Ascenzo M, Grassi C. GSK3β Modulates Timing-Dependent Long-Term Depression Through Direct Phosphorylation of Kv4.2 Channels. Cerebral Cortex (New York, N.Y. : 1991). PMID 29790931 DOI: 10.1093/cercor/bhy042  0.32
2018 Scala F, Nenov MN, Crofton EJ, Singh AK, Folorunso O, Zhang Y, Chesson BC, Wildburger NC, James TF, Alshammari MA, Alshammari TK, Elfrink H, Grassi C, Kasper JM, Smith AE, ... ... Laezza F, et al. Environmental Enrichment and Social Isolation Mediate Neuroplasticity of Medium Spiny Neurons through the GSK3 Pathway. Cell Reports. 23: 555-567. PMID 29642012 DOI: 10.1016/j.celrep.2018.03.062  0.72
2018 Ali SR, Liu Z, Nenov MN, Folorunso O, Singh AK, Scala F, Chen H, James TF, Alshammari M, Panova-Elektronova NI, White MA, Zhou J, Laezza F. Functional modulation of voltage-gated sodium channels by a FGF14-based peptidomimetic. Acs Chemical Neuroscience. PMID 29359916 DOI: 10.1021/acschemneuro.7b00399  0.92
2017 Hsu WJ, Wildburger N, Haidacher SJ, Nenov MN, Folorunso O, Singh AK, Chesson BC, Franklin WF, Cortez I, Sadygov RG, Dineley KT, Rudra J, Taglialatela G, Lichti CF, Denner L, ... Laezza F, et al. PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease. Experimental Neurology. PMID 28522250 DOI: 10.1016/j.expneurol.2017.05.005  0.56
2017 Di Re J, Wadsworth PA, Laezza F. Intracellular Fibroblast Growth Factor 14: Emerging Risk Factor for Brain Disorders. Frontiers in Cellular Neuroscience. 11: 103. PMID 28469558 DOI: 10.3389/fncel.2017.00103  0.32
2016 Alshammari TK, Alshammari MA, Nenov MN, Hoxha E, Cambiaghi M, Marcinno A, James TF, Singh P, Labate D, Li J, Meltzer HY, Sacchetti B, Tempia F, Laezza F. Genetic deletion of fibroblast growth factor 14 recapitulates phenotypic alterations underlying cognitive impairment associated with schizophrenia. Translational Psychiatry. 6: e806. PMID 27163207 DOI: 10.1038/tp.2016.66  0.68
2016 Ali SR, Singh AK, Laezza F. Identification of Amino Acid Residues in the Fibroblast Growth Factor 14 (FGF14) Required For Structure-Function interactions with the Voltage-Gated Sodium Channel Nav1.6. The Journal of Biological Chemistry. PMID 26994141 DOI: 10.1074/jbc.M115.703868  0.92
2016 Hsu WJ, Scala F, Nenov MN, Wildburger NC, Elferink H, Singh AK, Chesson CB, Buzhdygan T, Sohail M, Shavkunov AS, Panova NI, Nilsson CL, Rudra JS, Lichti CF, Laezza F. CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26917740 DOI: 10.1096/fj.201500161  1
2016 Alshammari MA, Alshammari TK, Laezza F. Improved Methods for Fluorescence Microscopy Detection of Macromolecules at the Axon Initial Segment. Frontiers in Cellular Neuroscience. 10: 5. PMID 26909021 DOI: 10.3389/fncel.2016.00005  1
2015 Alshammari MA, Alshammari TK, Nenov MN, Scala F, Laezza F. Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus. Molecular Neurobiology. PMID 26687232 DOI: 10.1007/s12035-015-9568-5  0.68
2015 Sowers J, Mirfattah B, Xu P, Tang H, Park IY, Walker C, Wu P, Laezza F, Sowers LC, Zhang K. Quantification of histone modifications by parallel-reaction-monitoring (PRM) - a method validation. Analytical Chemistry. PMID 26356480 DOI: 10.1021/acs.analchem.5b02615  1
2015 Tempia F, Hoxha E, Negro G, Alshammari MA, Alshammari TK, Panova-Elektronova N, Laezza F. Parallel fiber to Purkinje cell synaptic impairment in a mouse model of spinocerebellar ataxia type 27. Frontiers in Cellular Neuroscience. 9: 205. PMID 26089778 DOI: 10.3389/fncel.2015.00205  1
2015 Shavkunov AS, Ali SR, Panova-Elektronova NI, Laezza F. Split-luciferase complementation assay to detect channel-protein interactions in live cells. Methods in Molecular Biology (Clifton, N.J.). 1278: 497-514. PMID 25859972 DOI: 10.1007/978-1-4939-2425-7_33  1
2015 Ozcan B, Negi P, Laezza F, Papadakis M, Labate D. Automated detection of soma location and morphology in neuronal network cultures. Plos One. 10: e0121886. PMID 25853656 DOI: 10.1371/journal.pone.0121886  1
2015 Wildburger NC, Ali SR, Hsu WC, Shavkunov AS, Nenov MN, Lichti CF, LeDuc RD, Mostovenko E, Panova-Elektronova NI, Emmett MR, Nilsson CL, Laezza F. Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain. Molecular & Cellular Proteomics : McP. 14: 1288-300. PMID 25724910 DOI: 10.1074/mcp.M114.040055  1
2015 Hsu WC, Nenov MN, Shavkunov A, Panova N, Zhan M, Laezza F. Identifying a kinase network regulating FGF14:Nav1.6 complex assembly using split-luciferase complementation. Plos One. 10: e0117246. PMID 25659151 DOI: 10.1371/journal.pone.0117246  1
2015 Sallam HS, Tumurbaatar B, Zhang WR, Tuvdendorj D, Chandalia M, Tempia F, Laezza F, Taglialatela G, Abate N. Peripheral adipose tissue insulin resistance alters lipid composition and function of hippocampal synapses. Journal of Neurochemistry. 133: 125-33. PMID 25640170 DOI: 10.1111/jnc.13043  1
2015 James TF, Nenov MN, Wildburger NC, Lichti CF, Luisi J, Vergara F, Panova-Electronova NI, Nilsson CL, Rudra JS, Green TA, Labate D, Laezza F. The Nav1.2 channel is regulated by GSK3. Biochimica Et Biophysica Acta. 1850: 832-44. PMID 25615535 DOI: 10.1016/j.bbagen.2015.01.011  1
2015 Scala F, Fusco S, Ripoli C, Piacentini R, Li Puma DD, Spinelli M, Laezza F, Grassi C, D'Ascenzo M. Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3. Neurobiology of Aging. 36: 886-900. PMID 25541422 DOI: 10.1016/j.neurobiolaging.2014.10.034  1
2015 Nenov MN, Tempia F, Denner L, Dineley KT, Laezza F. Impaired firing properties of dentate granule neurons in an Alzheimer's disease animal model are rescued by PPARγ agonism. Journal of Neurophysiology. 113: 1712-26. PMID 25540218 DOI: 10.1152/jn.00419.2014  1
2014 Hsu WC, Nilsson CL, Laezza F. Role of the axonal initial segment in psychiatric disorders: function, dysfunction, and intervention. Frontiers in Psychiatry. 5: 109. PMID 25191280 DOI: 10.3389/fpsyt.2014.00109  1
2014 Nenov MN, Laezza F, Haidacher SJ, Zhao Y, Sadygov RG, Starkey JM, Spratt H, Luxon BA, Dineley KT, Denner L. Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 1028-36. PMID 24431460 DOI: 10.1523/JNEUROSCI.3413-13.2014  1
2014 Emmett MR, Kroes RA, Moskal JR, Conrad CA, Priebe W, Laezza F, Meyer-Baese A, Nilsson CL. Integrative biological analysis for neuropsychopharmacology. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 5-23. PMID 23800968 DOI: 10.1038/npp.2013.156  1
2014 Adhikari AR, Rusakova I, Haleh A, Luisi J, Panova NI, Laezza F, Chu WK. Thermal property and assessment of biocompatibility of poly(lactic-co- glycolic) acid/graphene nanocomposites Journal of Applied Physics. 115. DOI: 10.1063/1.4864263  1
2014 Damanik D, Ruzhansky M, Vougalter V, Wong MW, Labate D, Laezza F, Negi P, Ozcan B, Papadakis M. Efficient processing of fluorescence images using directional multiscale representations Mathematical Modelling of Natural Phenomena. 9: 177-193. DOI: 10.1051/mmnp/20149512  1
2014 Ali S, Shavkunov A, Panova N, Stoilova-McPhie S, Laezza F. Modulation of the FGF14: FGF14 homodimer interaction through short peptide fragments Cns and Neurological Disorders - Drug Targets. 13: 1559-1570.  1
2013 Shavkunov AS, Wildburger NC, Nenov MN, James TF, Buzhdygan TP, Panova-Elektronova NI, Green TA, Veselenak RL, Bourne N, Laezza F. The fibroblast growth factor 14·voltage-gated sodium channel complex is a new target of glycogen synthase kinase 3 (GSK3). The Journal of Biological Chemistry. 288: 19370-85. PMID 23640885 DOI: 10.1074/jbc.M112.445924  1
2013 Anastasio NC, Gilbertson SR, Bubar MJ, Agarkov A, Stutz SJ, Jeng Y, Bremer NM, Smith TD, Fox RG, Swinford SE, Seitz PK, Charendoff MN, Craft JW, Laezza FM, Watson CS, et al. Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 1615-30. PMID 23345234 DOI: 10.1523/JNEUROSCI.2656-12.2013  1
2012 Wildburger NC, Laezza F. Control of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase. Frontiers in Molecular Neuroscience. 5: 80. PMID 22811658 DOI: 10.3389/fnmol.2012.00080  1
2012 Shavkunov A, Panova N, Prasai A, Veselenak R, Bourne N, Stoilova-McPhie S, Laezza F. Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex. Assay and Drug Development Technologies. 10: 148-60. PMID 22364545 DOI: 10.1089/adt.2011.413  1
2011 Reese LC, Laezza F, Woltjer R, Taglialatela G. Dysregulated phosphorylation of Ca(2+) /calmodulin-dependent protein kinase II-α in the hippocampus of subjects with mild cognitive impairment and Alzheimer's disease. Journal of Neurochemistry. 119: 791-804. PMID 21883216 DOI: 10.1111/j.1471-4159.2011.07447.x  1
2011 Laezza F, Dingledine R. Induction and expression rules of synaptic plasticity in hippocampal interneurons. Neuropharmacology. 60: 720-9. PMID 21195098 DOI: 10.1016/j.neuropharm.2010.12.016  1
2009 Laezza F, Lampert A, Kozel MA, Gerber BR, Rush AM, Nerbonne JM, Waxman SG, Dib-Hajj SD, Ornitz DM. FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels. Molecular and Cellular Neurosciences. 42: 90-101. PMID 19465131 DOI: 10.1016/j.mcn.2009.05.007  1
2009 Goetz R, Dover K, Laezza F, Shtraizent N, Huang X, Tchetchik D, Eliseenkova AV, Xu CF, Neubert TA, Ornitz DM, Goldfarb M, Mohammadi M. Crystal structure of a fibroblast growth factor homologous factor (FHF) defines a conserved surface on FHFs for binding and modulation of voltage-gated sodium channels. The Journal of Biological Chemistry. 284: 17883-96. PMID 19406745 DOI: 10.1074/jbc.M109.001842  1
2008 Laezza F, Wilding TJ, Sequeira S, Craig AM, Huettner JE. The BTB/kelch protein, KRIP6, modulates the interaction of PICK1 with GluR6 kainate receptors. Neuropharmacology. 55: 1131-9. PMID 18692513 DOI: 10.1016/j.neuropharm.2008.07.021  1
2007 Laezza F, Gerber BR, Lou JY, Kozel MA, Hartman H, Craig AM, Ornitz DM, Nerbonne JM. The FGF14(F145S) mutation disrupts the interaction of FGF14 with voltage-gated Na+ channels and impairs neuronal excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 12033-44. PMID 17978045 DOI: 10.1523/JNEUROSCI.2282-07.2007  1
2007 Laezza F, Wilding TJ, Sequeira S, Coussen F, Zhang XZ, Hill-Robinson R, Mulle C, Huettner JE, Craig AM. KRIP6: a novel BTB/kelch protein regulating function of kainate receptors. Molecular and Cellular Neurosciences. 34: 539-50. PMID 17254796 DOI: 10.1016/j.mcn.2006.12.003  1
2007 Xiao M, Xu L, Laezza F, Yamada K, Feng S, Ornitz DM. Impaired hippocampal synaptic transmission and plasticity in mice lacking fibroblast growth factor 14. Molecular and Cellular Neurosciences. 34: 366-77. PMID 17208450 DOI: 10.1016/j.mcn.2006.11.020  1
2005 Lou JY, Laezza F, Gerber BR, Xiao M, Yamada KA, Hartmann H, Craig AM, Nerbonne JM, Ornitz DM. Fibroblast growth factor 14 is an intracellular modulator of voltage-gated sodium channels. The Journal of Physiology. 569: 179-93. PMID 16166153 DOI: 10.1113/jphysiol.2005.097220  1
2004 Laezza F, Dingledine R. Voltage-controlled plasticity at GluR2-deficient synapses onto hippocampal interneurons. Journal of Neurophysiology. 92: 3575-81. PMID 15331617 DOI: 10.1152/jn.00425.2004  1
1999 Laezza F, Doherty JJ, Dingledine R. Long-term depression in hippocampal interneurons: joint requirement for pre- and postsynaptic events. Science (New York, N.Y.). 285: 1411-4. PMID 10464102 DOI: 10.1126/science.285.5432.1411  1
1995 Distasi C, Munaron L, Laezza F, Lovisolo D. Basic fibroblast growth factor opens calcium-permeable channels in quail mesencephalic neural crest neurons. The European Journal of Neuroscience. 7: 516-20. PMID 7773448 DOI: 10.1111/j.1460-9568.1995.tb00348.x  1
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