Brock Grill, Ph.D. - Publications

Affiliations: 
2009-2012 Pharmacology University of Minnesota, Twin Cities, Minneapolis, MN 
 2012- Neuroscience The Scripps Research Institute, Scripps Florida 
Area:
Molecular mechanisms of axon termination and synapse formation

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Giles AC, Grill B. Roles of the HUWE1 ubiquitin ligase in nervous system development, function and disease. Neural Development. 15: 6. PMID 32336296 DOI: 10.1186/s13064-020-00143-9  0.88
2019 Crawley O, Opperman KJ, Desbois M, Adrados I, Borgen MA, Giles AC, Duckett DR, Grill B. Autophagy is inhibited by ubiquitin ligase activity in the nervous system. Nature Communications. 10: 5017. PMID 31676756 DOI: 10.1038/s41467-019-12804-3  1
2019 Wang D, Stoveken HM, Zucca S, Dao M, Orlandi C, Song C, Masuho I, Johnston C, Opperman KJ, Giles AC, Gill MS, Lundquist EA, Grill B, Martemyanov KA. Genetic behavioral screen identifies an orphan anti-opioid system. Science (New York, N.Y.). PMID 31416932 DOI: 10.1126/science.aau2078  0.88
2019 Giles AC, Desbois M, Opperman KJ, Tavora R, Maroni MJ, Grill B. A complex containing the O-GlcNAc transferase OGT-1 and the ubiquitin ligase EEL-1regulates GABA neuron function. The Journal of Biological Chemistry. PMID 30858176 DOI: 10.1074/jbc.RA119.007406  0.88
2019 Borgen MA, Giles AC, Wang D, Grill B. Synapse maintenance is impacted by ATAT-2 tubulin acetyltransferase activity and the RPM-1 signaling hub. Elife. 8. PMID 30652969 DOI: 10.7554/eLife.44040  1
2018 Desbois M, Crawley O, Evans PR, Baker ST, Masuho I, Yasuda R, Grill B. PAM forms an atypical SCF ubiquitin ligase complex that ubiquitinates and degrades NMNAT2. The Journal of Biological Chemistry. PMID 29997255 DOI: 10.1074/jbc.RA118.002176  0.76
2017 Crawley O, Giles AC, Desbois M, Kashyap S, Birnbaum R, Grill B. A MIG-15/JNK-1 MAP kinase cascade opposes RPM-1 signaling in synapse formation and learning. Plos Genetics. 13: e1007095. PMID 29228003 DOI: 10.1371/journal.pgen.1007095  0.88
2017 Borgen MA, Wang D, Grill B. RPM-1 regulates axon termination by affecting growth cone collapse and microtubule stability. Development (Cambridge, England). PMID 29084805 DOI: 10.1242/dev.154187  1
2017 Opperman KJ, Mulcahy B, Giles AC, Risley MG, Birnbaum RL, Tulgren ED, Dawson-Scully K, Zhen M, Grill B. The HECT Family Ubiquitin Ligase EEL-1 Regulates Neuronal Function and Development. Cell Reports. 19: 822-835. PMID 28445732 DOI: 10.1016/j.celrep.2017.04.003  0.88
2016 Baker ST, Grill B. Defining minimal binding regions in Regulator of Presynaptic Morphology 1 (RPM-1) using C. elegans neurons reveals differential signaling complexes. The Journal of Biological Chemistry. PMID 27979965 DOI: 10.1074/jbc.M116.748004  0.76
2016 Risley MG, Kelly SP, Jia K, Grill B, Dawson-Scully K. Modulating Behavior in C. elegans Using Electroshock and Antiepileptic Drugs. Plos One. 11: e0163786. PMID 27668426 DOI: 10.1371/journal.pone.0163786  0.72
2016 Grill B, Murphey RK, Borgen MA. The PHR proteins: intracellular signaling hubs in neuronal development and axon degeneration. Neural Development. 11: 8. PMID 27008623 DOI: 10.1186/s13064-016-0063-0  1
2015 Giles AC, Opperman KJ, Rankin CH, Grill B. Developmental Function of the PHR Protein RPM-1 Is Required for Learning in Caenorhabditis elegans. G3 (Bethesda, Md.). PMID 26464359 DOI: 10.1534/g3.115.021410  1
2015 Baker ST, Turgeon SM, Tulgren ED, Wigant J, Rahimi O, Opperman KJ, Grill B. Neuronal development in Caenorhabditis elegans is regulated by inhibition of an MLK MAP kinase pathway. Genetics. 199: 151-6. PMID 25339611 DOI: 10.1534/genetics.114.170589  1
2014 Sharma J, Baker ST, Turgeon SM, Gurney AM, Opperman KJ, Grill B. Identification of a peptide inhibitor of the RPM-1 · FSN-1 ubiquitin ligase complex. The Journal of Biological Chemistry. 289: 34654-66. PMID 25326385 DOI: 10.1074/jbc.M114.614065  1
2014 Tulgren ED, Turgeon SM, Opperman KJ, Grill B. The Nesprin family member ANC-1 regulates synapse formation and axon termination by functioning in a pathway with RPM-1 and β-Catenin. Plos Genetics. 10: e1004481. PMID 25010424 DOI: 10.1371/journal.pgen.1004481  1
2014 Opperman KJ, Grill B. RPM-1 is localized to distinct subcellular compartments and regulates axon length in GABAergic motor neurons. Neural Development. 9: 10. PMID 24885325 DOI: 10.1186/1749-8104-9-10  1
2014 Baker ST, Opperman KJ, Tulgren ED, Turgeon SM, Bienvenut W, Grill B. RPM-1 uses both ubiquitin ligase and phosphatase-based mechanisms to regulate DLK-1 during neuronal development. Plos Genetics. 10: e1004297. PMID 24810406 DOI: 10.1371/journal.pgen.1004297  1
2012 Grill B, Chen L, Tulgren ED, Baker ST, Bienvenut W, Anderson M, Quadroni M, Jin Y, Garner CC. RAE-1, a novel PHR binding protein, is required for axon termination and synapse formation in Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 2628-36. PMID 22357847 DOI: 10.1523/JNEUROSCI.2901-11.2012  1
2011 Tulgren ED, Baker ST, Rapp L, Gurney AM, Grill B. PPM-1, a PP2Cα/β phosphatase, regulates axon termination and synapse formation in Caenorhabditis elegans. Genetics. 189: 1297-307. PMID 21968191 DOI: 10.1534/genetics.111.134791  1
2008 Margeta MA, Shen K, Grill B. Building a synapse: lessons on synaptic specificity and presynaptic assembly from the nematode C. elegans. Current Opinion in Neurobiology. 18: 69-76. PMID 18538560 DOI: 10.1016/j.conb.2008.04.003  1
2008 Abrams B, Grill B, Huang X, Jin Y. Cellular and molecular determinants targeting the Caenorhabditis elegans PHR protein RPM-1 to perisynaptic regions. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 630-9. PMID 18224716 DOI: 10.1002/dvdy.21446  1
2007 Grill B, Bienvenut WV, Brown HM, Ackley BD, Quadroni M, Jin Y. C. elegans RPM-1 regulates axon termination and synaptogenesis through the Rab GEF GLO-4 and the Rab GTPase GLO-1. Neuron. 55: 587-601. PMID 17698012 DOI: 10.1016/j.neuron.2007.07.009  1
2006 Dai Y, Taru H, Deken SL, Grill B, Ackley B, Nonet ML, Jin Y. SYD-2 Liprin-alpha organizes presynaptic active zone formation through ELKS. Nature Neuroscience. 9: 1479-87. PMID 17115037 DOI: 10.1038/nn1808  1
2005 Nakata K, Abrams B, Grill B, Goncharov A, Huang X, Chisholm AD, Jin Y. Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development. Cell. 120: 407-20. PMID 15707898 DOI: 10.1016/j.cell.2004.12.017  1
2004 Grill B, Wilson GM, Zhang KX, Wang B, Doyonnas R, Quadroni M, Schrader JW. Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins. Journal of Immunology (Baltimore, Md. : 1950). 172: 2389-400. PMID 14764709  1
2002 Grill B, Schrader JW. Activation of Rac-1, Rac-2, and Cdc42 by hemopoietic growth factors or cross-linking of the B-lymphocyte receptor for antigen. Blood. 100: 3183-92. PMID 12384416 DOI: 10.1182/blood-2002-01-0154  1
2002 Schrader JW, Schallhorn A, Grill B, Guo X. Activation of small GTPases of the Ras and Rho family by growth factors active on mast cells. Molecular Immunology. 38: 1181-6. PMID 12217381 DOI: 10.1016/S0161-5890(02)00060-3  1
2002 Leslie DM, Grill B, Rout MP, Wozniak RW, Aitchison JD. Kap121p-mediated nuclear import is required for mating and cellular differentiation in yeast. Molecular and Cellular Biology. 22: 2544-55. PMID 11909949 DOI: 10.1128/MCB.22.8.2544-2555.2002  1
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