Megan Huizenga - Related publications

Affiliations: 
2014- Pharmacology  Georgetown University, Washington, DC 
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Paudel YN, Kumari Y, Abidin SAZ, Othman I, Shaikh MF. Pilocarpine Induced Behavioral and Biochemical Alterations in Chronic Seizure-Like Condition in Adult Zebrafish. International Journal of Molecular Sciences. 21. PMID 32260203 DOI: 10.3390/ijms21072492   
2020 Li X, Himes RA, Prosser LC, Christie CF, Watt E, Edwards SF, Metcalf C, West P, Wilcox K, Chan SSL, Chou CJ. Discovery of the first Vitamin K analog as a potential treatment of pharmacoresistant seizures. Journal of Medicinal Chemistry. PMID 32390424 DOI: 10.1021/acs.jmedchem.0c00168   
2020 Thomson KE, Metcalf CS, Newell TG, Huff J, Edwards SF, West PJ, Wilcox KS. Evaluation of subchronic administration of antiseizure drugs in spontaneously seizing rats. Epilepsia. PMID 32420627 DOI: 10.1111/epi.16531   
2020 Zhang Y, Han Y, Chen Z, Zhao D, Xia Q. Inhibition of EZH2 attenuates inhibitory synaptic transmission via the pro-inflammatory pathway in rats. Neuropharmacology. 108101. PMID 32298702 DOI: 10.1016/j.neuropharm.2020.108101   
2020 Yu Y, Li L, Nguyen DT, Mustafa SM, Moore BM, Jiang J. Inverse Agonism of Cannabinoid Receptor Type 2 Confers Anti-inflammatory and Neuroprotective Effects Following Status Epileptics. Molecular Neurobiology. PMID 32378121 DOI: 10.1007/s12035-020-01923-4   
2020 Savaş M, Tzartos J, Küçükali Cİ, Dursun E, Karagiorgou K, Gezen-Ak D, Türkdoğan D, Papaconstantinou A, Başoğlu S, Hacıhafızoğlu N, Kutlubay B, Tzartos S, Tüzün E. Glial fibrillary acidic protein (GFAP)-antibody in children with focal seizures of undetermined cause. Acta Neurologica Belgica. PMID 32333263 DOI: 10.1007/s13760-020-01361-y   
2020 Sharpe C, Reiner GE, Davis SL, Nespeca M, Gold JJ, Rasmussen M, Kuperman R, Harbert MJ, Michelson D, Joe P, Wang S, Rismanchi N, Le NM, Mower A, Kim J, ... , et al. Levetiracetam Versus Phenobarbital for Neonatal Seizures: A Randomized Controlled Trial. Pediatrics. PMID 32385134 DOI: 10.1542/peds.2019-3182   
2020 Wang Y, Yu Y, Hu Y, Li Y, Song F, Wang Y. Clinical and Electroencephalographic Features of the Seizures in Neuronal Surface Antibody-Associated Autoimmune Encephalitis. Frontiers in Neurology. 11: 280. PMID 32431657 DOI: 10.3389/fneur.2020.00280   
2020 Pradhan S, Das A, Mulmuley M, Das A. Neurocysticercosis or tuberculoma - Which one has more epileptic potential? Seizure. 78: 91-95. PMID 32278296 DOI: 10.1016/j.seizure.2020.03.007   
2020 Xi XJ, Tang JH, Zhang BB, Shi XY, Feng J, Hu XY, Wan Y, Zhou C. Recurrent seizures cause immature brain injury and changes in GABA a receptor α1 and γ2 subunits. Epilepsy Research. 163: 106328. PMID 32283447 DOI: 10.1016/j.eplepsyres.2020.106328   
2020 Nazar S, Siddiqui N, Alam O. Recent progress of 1,3,4-oxadiazoles as anticonvulsants: Future horizons. Archiv Der Pharmazie. e1900342. PMID 32319117 DOI: 10.1002/ardp.201900342   
2020 von Blomberg A, Kay L, Knake S, Fuest S, Zöllner JP, Reif PS, Herrmann E, Balaban Ü, Schubert-Bast S, Rosenow F, Strzelczyk A. Efficacy, Tolerability, and Safety of Concentrated Intranasal Midazolam Spray as Emergency Medication in Epilepsy Patients During Video-EEG Monitoring. Cns Drugs. PMID 32219682 DOI: 10.1007/s40263-020-00720-w   
2020 Muñana KR, Nettifee JA, Griffith EH, Early PJ, Yoder NC. Evaluation of a collar-mounted accelerometer for detecting seizure activity in dogs. Journal of Veterinary Internal Medicine. PMID 32293068 DOI: 10.1111/jvim.15760   
2020 Zou J, Meng L, Lin Z, Qiao Y, Tie C, Wang Y, Huang X, Yuan T, Chi Y, Meng W, Niu L, Guo Y, Zheng H. Ultrasound Neuromodulation Inhibits Seizures in Acute Epileptic Monkeys. Iscience. 23: 101066. PMID 32361593 DOI: 10.1016/j.isci.2020.101066   
2020 González EA, Rindy AC, Guignet MA, Calsbeek JJ, Bruun DA, Dhir A, Andrew P, Saito N, Rowland DJ, Harvey DJ, Rogawski MA, Lein PJ. The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity. Archives of Toxicology. PMID 32303805 DOI: 10.1007/s00204-020-02747-w   
2020 O'Brien TJ, Borghs S, He QJ, Schulz AL, Yates S, Biton V. Long-term safety, efficacy, and quality of life outcomes with adjunctive brivaracetam treatment at individualized doses in patients with epilepsy: An up to 11-year, open-label, follow-up trial. Epilepsia. PMID 32221987 DOI: 10.1111/epi.16484   
2020 Maguire MJ, Jackson CF, Marson AG, Nevitt SJ. Treatments for the prevention of Sudden Unexpected Death in Epilepsy (SUDEP). The Cochrane Database of Systematic Reviews. 4: CD011792. PMID 32239759 DOI: 10.1002/14651858.CD011792.pub3   
2020 McCarthy E, Shakil F, Saint Ange P, Morris Cameron E, Miller J, Pathak S, Greenberg DA, Velíšková J, Velíšek L. Developmental decrease in parvalbumin-positive neurons precedes increase in flurothyl-induced seizure susceptibility in the Brd2 mouse model of juvenile myoclonic epilepsy. Epilepsia. PMID 32301507 DOI: 10.1111/epi.16499   
2020 Vernillet L, Greene SA, Kim HW, Melnick SM, Glenn K. Mass Balance, Metabolism, and Excretion of Cenobamate, a New Antiepileptic Drug, After a Single Oral Administration in Healthy Male Subjects. European Journal of Drug Metabolism and Pharmacokinetics. PMID 32301064 DOI: 10.1007/s13318-020-00615-7   
2020 Cook M, Murphy M, Bulluss K, D'Souza W, Plummer C, Priest E, Williams C, Sharan A, Fisher R, Pincus S, Distad E, Anchordoquy T, Abrams D. Anti-seizure therapy with a long-term, implanted intra-cerebroventricular delivery system for drug-resistant epilepsy: A first-in-man study. Eclinicalmedicine. 22: 100326. PMID 32395709 DOI: 10.1016/j.eclinm.2020.100326   
2020 Roth J, Bercovich O, Roach A, Mangano FT, Mohan AC, Aldave G, Weiner HL, Thomale UW, Schaumann A, Uliel-Sibony S, Constantini S. Seizures following surgery for supratentorial extratemporal low-grade tumors in children: a multicenter retrospective study. Journal of Neurosurgery. Pediatrics. 1-7. PMID 32244217 DOI: 10.3171/2020.2.PEDS19673   
2020 Tang Y, Feng B, Wang Y, Sun H, You Y, Yu J, Chen B, Xu C, Ruan Y, Cui S, Hu G, Hou T, Chen Z. Structure-based discovery of caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility. British Journal of Pharmacology. PMID 32346861 DOI: 10.1111/bph.15076   
2020 Song L, Liu F, Liu Y, Zhang R, Ji H, Jia Y. Clonazepam add-on therapy for drug-resistant epilepsy. The Cochrane Database of Systematic Reviews. 4: CD012253. PMID 32309880 DOI: 10.1002/14651858.CD012253.pub3   
2020 Ge YX, Lin YY, Bi QQ, Chen YJ. Brivaracetam prevents the over-expression of synaptic vesicle protein 2A and rescues the deficits of hippocampal Long-term potentiation in vivo in chronic temporal lobe epilepsy rats. Current Neurovascular Research. PMID 32407277 DOI: 10.2174/1567202617666200514114917   
2020 Dunn EN, Matson LM, Haines KM, Whitten KA, Lee-Stubbs RB, Berger KE, McCarren HS, Ardinger CE, Jackson Piercy CE, Miller-Smith SM, McDonough JH. Evaluation of fosphenytoin, levetiracetam, and propofol as treatments for nerve agent-induced seizures in pediatric and adult rats. Neurotoxicology. PMID 32220603 DOI: 10.1016/j.neuro.2020.03.007   
2020 Kipnis PA, Sullivan BJ, Carter BM, Kadam S. TrkB-agonists prevent post-ischemic emergence of refractory neonatal seizures in mice. Jci Insight. PMID 32427585 DOI: 10.1172/jci.insight.136007   
2020 Sheikh ZB, Stretz C, Maciel CB, Dhakar MB, Orgass H, Petroff OA, Hirsch LJ, Gilmore EJ. Deep Versus Lobar Intraparenchymal Hemorrhage: Seizures, Hyperexcitable Patterns, and Clinical Outcomes. Critical Care Medicine. PMID 32301843 DOI: 10.1097/CCM.0000000000004317   
2020 Rojas A, Wang J, Glover A, Dingledine R. Urethane attenuates early neuropathology of diisopropylfluorophosphate-induced status epilepticus in rats. Neurobiology of Disease. 104863. PMID 32283202 DOI: 10.1016/j.nbd.2020.104863   
2020 Chen RJ, Ershad M, Dela Cruz M, Mostafa AMT. Carbamazepine Toxicity Masquerading as Complex Febrile Seizures in a Pediatric Patient. Case Reports in Emergency Medicine. 2020: 1790310. PMID 32257458 DOI: 10.1155/2020/1790310   
2020 De Araujo Furtado M, Aroniadou-Anderjaska V, Figueiredo TH, Apland JP, Braga MFM. Electroencephalographic analysis in soman-exposed 21-day-old rats and the effects of midazolam or LY293558 with caramiphen. Annals of the New York Academy of Sciences. PMID 32237259 DOI: 10.1111/nyas.14331   
2020 Kraus L, Monni L, Schneider UC, Onken J, Spindler P, Holtkamp M, Fidzinski P. Preparation of Acute Human Hippocampal Slices for Electrophysiological Recordings. Journal of Visualized Experiments : Jove. PMID 32449727 DOI: 10.3791/61085   
2020 Carcak N, Sahiner M, Akman O, Idrizoglu MG, Cortez MA, Snead OC, Eskazan E, Onat F. Pharmacologically induced absence seizures kindling in Wistar rats. Northern Clinics of Istanbul. 7: 25-34. PMID 32232200 DOI: 10.14744/nci.2019.80664   
2020 Soldozy S, Norat P, Yağmurlu K, Sokolowski JD, Sharifi KA, Tvrdik P, Park MS, Kalani MYS. Arteriovenous malformation presenting with epilepsy: a multimodal approach to diagnosis and treatment. Neurosurgical Focus. 48: E17. PMID 32234990 DOI: 10.3171/2020.1.FOCUS19899   
2020 Shen CH, Zheng Y, Cai MT, Yang F, Fang W, Zhang YX, Ding MP. Seizure occurrence in myelin oligodendrocyte glycoprotein antibody-associated disease: A systematic review and meta-analysis. Multiple Sclerosis and Related Disorders. 42: 102057. PMID 32222694 DOI: 10.1016/j.msard.2020.102057   
2020 Duy PQ, He M, He Z, Kahle KT. Preclinical insights into therapeutic targeting of KCC2 for disorders of neuronal hyperexcitability. Expert Opinion On Therapeutic Targets. PMID 32336175 DOI: 10.1080/14728222.2020.1762174   
2020 Berk BA, Law TH, Packer RMA, Wessmann A, Bathen-Nöthen A, Jokinen TS, Knebel A, Tipold A, Pelligand L, Meads Z, Volk HA. A multicenter randomized controlled trial of medium-chain triglyceride dietary supplementation on epilepsy in dogs. Journal of Veterinary Internal Medicine. PMID 32293065 DOI: 10.1111/jvim.15756   
2020 Montgomery MK, Kim SH, Dovas A, Zhao HT, Goldberg AR, Xu W, Yagielski AJ, Cambareri MK, Patel KB, Mela A, Humala N, Thibodeaux DN, Shaik MA, Ma Y, Grinband J, et al. Glioma-Induced Alterations in Neuronal Activity and Neurovascular Coupling during Disease Progression. Cell Reports. 31: 107500. PMID 32294436 DOI: 10.1016/j.celrep.2020.03.064   
2020 Dong X, Zhang X, Wang F, Liu N, Liu A, Li Y, Wei L, Chen F, Yuan S, Zhang K, Hou S, Jiao Q, Hu Q, Guo C, Wu T, et al. Simultaneous calcium recordings of hippocampal CA1 and primary motor cortex M1 and their relations to behavioral activities in freely moving epileptic mice. Experimental Brain Research. PMID 32424694 DOI: 10.1007/s00221-020-05815-w   
2020 Khoo CS, Kim SE, Lee BI, Shin KJ, Ha SY, Park J, Park KM, Bae SY, Lee D, Kim BJ, Bae MJ, Kim SE. Characteristics of Perfusion Computed Tomography Imaging in Patients with Seizures Mimicking Acute Stroke. European Neurology. 1-9. PMID 32320976 DOI: 10.1159/000506591   
2020 Zions M, Meehan EF, Kress ME, Thevalingam D, Jenkins EC, Kaila K, Puskarjov M, McCloskey DP. Nest Carbon Dioxide Masks GABA-Dependent Seizure Susceptibility in the Naked Mole-Rat. Current Biology : Cb. PMID 32359429 DOI: 10.1016/j.cub.2020.03.071   
2020 Uziel A, Gelfand A, Amsalem K, Berman P, Lewitus GM, Meiri D, Lewitus DY. Full-Spectrum Extract Microdepots Support Controlled Release of Multiple Phytocannabinoids for Extended Therapeutic Effect. Acs Applied Materials & Interfaces. PMID 32369348 DOI: 10.1021/acsami.0c04435   
2020 Zuo D, Wang F, Rong W, Wen Y, Sun K, Zhao X, Ren X, He Z, Ding N, Ma L, Xu F. The novel estrogen receptor GPER1 decreases epilepsy severity and susceptivity in the hippocampus after status epilepticus. Neuroscience Letters. 134978. PMID 32302699 DOI: 10.1016/j.neulet.2020.134978   
2020 Giorgi FS, Galgani A, Gaglione A, Ferese R, Fornai F. Effects of Prolonged Seizures on Basal Forebrain Cholinergic Neurons: Evidence and Potential Clinical Relevance. Neurotoxicity Research. PMID 32319018 DOI: 10.1007/s12640-020-00198-w   
2020 Wang M, Deng X, Xie Y, Chen Y. Astaxanthin Attenuates Neuroinflammation in Status Epilepticus Rats by Regulating the ATP-P2X7R Signal. Drug Design, Development and Therapy. 14: 1651-1662. PMID 32431490 DOI: 10.2147/DDDT.S249162   
2020 Paudel YN, Angelopoulou E, Piperi C, Gnatkovsky V, Othman I, Shaikh MF. From molecular mechanism to pre-clinical results: Anti-epileptic effects of Fingolimod. Current Neuropharmacology. PMID 32310049 DOI: 10.2174/1570159X18666200420125017   
2020 Urbach H, Berger B, Solymosi L, Zimmermann J. "Negative T2 shine through" in patients with hyperglycemia and seizures: a frequently overlooked MRI pattern. Neuroradiology. PMID 32219491 DOI: 10.1007/s00234-020-02408-w   
2020 Tan C, Liu X, Peng W, Wang H, Zhou W, Jiang J, Wei X, Mo L, Chen Y, Chen L. Seizure-induced impairment in neuronal ketogenesis: Role of zinc-α2-glycoprotein in mitochondria. Journal of Cellular and Molecular Medicine. PMID 32340079 DOI: 10.1111/jcmm.15337   
2020 Ren L, Yu T, Wang D, Wang X, Ni D, Zhang G, Bartolomei F, Wang Y, Li Y. Subthalamic nucleus stimulation modulates motor epileptic activity in humans. Annals of Neurology. PMID 32396256 DOI: 10.1002/ana.25776   
2020 Ren L, Yu T, Wang D, Wang X, Ni D, Zhang G, Bartolomei F, Wang Y, Li Y. Subthalamic nucleus stimulation modulates motor epileptic activity in humans. Annals of Neurology. PMID 32396256 DOI: 10.1002/ana.25776   
2020 Dowa Y, Shiihara T, Akiyama T, Hasegawa K, Inoue F, Watanabe M. A case of pyridoxine-dependent epilepsy with novel mutations. Oxford Medical Case Reports. 2020: omaa008. PMID 32395249 DOI: 10.1093/omcr/omaa008