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High-probability grants
According to our matching algorithm, Brenton Grant Cooper is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
1998 — 1999 |
Cooper, Brenton G |
F31Activity Code Description: To provide predoctoral individuals with supervised research training in specified health and health-related areas leading toward the research degree (e.g., Ph.D.). |
Retrosplenial Cortex Contributions to Spatial Navigation
DESCRIPTION (Adapted from applicant's abstract): The present proposal seeks to address how multiple structures interact to mediate active navigation. The ability to learn and remember locations of important resources is absolutely critical for every animal's ability to survive. As such, it is of great importance to understand how neural systems interact to mediate this behavior. The proposed studies will evaluate cortical contributions to processing of spatial information in hippocampus and limbic thalamus. Past anatomical, lesion and electrophysiological data suggest the retrosplenial cortex may make unique contributions to spatial learning. It is hypothesized here that retrosplenial cortex importantly contributes to the integration of visual and self movement information in limbic structures thought to be involved in navigation. To test this hypothesis, permanent lesions and temporary inactivation of retrosplenial cortex will be combined with chronic single unit recording from hippocampus and thalamus during active navigation. Behavioral probe trials will be used to identify changes in behavioral strategies following removal of retrosplenial cortex. It is predicted that in the absence of retrosplenial cortex the integration of visual and self movement information will be diminished in spatial correlates recorded from thalamus and hippocampus and behavioral data will reflect similar changes in behavioral strategies underlying spatial memory performance.
|
0.936 |
2002 — 2004 |
Cooper, Brenton G |
F32Activity Code Description: To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in specified health-related areas. |
Motor Correlates of Song Plasticity in Adult Songbirds
DESCRIPTION (provided by applicant): Birdsong is an animal model system for exploring issues in sensorimotor integration, learning and memory, and social modulation of behavior. The proposal seeks to develop an understanding of how respiratory and syringeal motor mechanisms of sound production are changed in response to altered acoustic feedback. We have developed a technique for reducing a bird's ability to vocalize. The technique can be maintained for long periods of time and is reversible. We propose to use this technique to alter acoustic feedback, and to examine how motor mechanisms of sound production change in response to this manipulation. Three experiments are proposed. The first will compare song changes in a variety of species following the partial muting procedure. The second experiment will characterize respiratory and syringeal motor compensation following the partial muting procedure, and the last experiment will compare respiratory and syringeal motor changes after deafening and damage to the vocal motor nerve. The results will be further our understanding of how vocal plasticity is manifested in motor correlates of song.
|
0.936 |