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High-probability grants
According to our matching algorithm, John Schlag is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
1985 — 2000 |
Schlag, John D |
R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. |
Conditioning of Pyramidal Activity by Sensory Inflow @ University of California Los Angeles
The long-term objective of this research is to study forebrain mechanisms involved in the initiation of movements. Single-unit recordings will be made in the frontal lobe of alert monkeys performing various tasks of spatial discrimination. Unit activity will be analyzed to determine how neurons encode spatial information on target locations and goals of movements. The frontal eye field will be investigated first in relation with the performance of ocular saccades and head rotations towar real or anticipated, visual or auditory stimuli. Subsequently, the experiments will be extended to include the region around sulcus principalis and the performance of hand movements toward targets.
|
0.958 |
1994 — 1996 |
Schlag, John D |
R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. |
Conditioning of Pyrimidal Activity by Sensory Inflow @ University of California Los Angeles
The long-term objective of this research is to study forebrain mechanisms involved in the initiation of eye movement. Extracellular recording from single neurons of the cerebral frontal and parietal lobes will be performed in alert monkeys. The neural signals will be analyzed in relation with eye and head movements measured by the magnetic search coil technique. The animals will be trained to acquire, pursue and anticipate visual targets presented on a screen, and to search for visual cues in a complex array of stimuli. Single neuron activity will be observed during the movements required by these tasks and movements occurring spontaneously. The aim is to understand how target location is encoded and proper commands are derived to specify the goal of a gaze movement. During the present project period, the dynamics of cooperation between cortical areas will be explored using microstimulation and recording.
|
0.958 |
2001 — 2003 |
Schlag, John D |
R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. |
Conditionng of Pyramidal Activity by Sensory Inflow @ University of California Los Angeles
The long-term objective of this research is to study forebrain mechanisms responsible for the initiation of ocular saccades. During the present project period, the focus is on two aspects of saccade initiation: one is the mechanism by which oculomotor centers interact and concur on the goal of the next saccade, and the other is the role played by the internal signal representing eye position to locate memorized target sites. One specific aim is to explore the dynamics of cooperation between the two main cortical oculomotor centers: the lateral intraparietal area and the frontal eye field. Electrophysiological experiments will be performed on trained monkeys Single-unit activity will be simultaneously recorded with microelectrodes in both areas, and compared during the performance of delayed-response and memory visuo-oculomotor tasks. We shall also record from each of these areas, the activity that accompanies saccades electrically evoked from the other area. This activity will be analyzed as a function of the matching of receptive field or movement fields represented by neurons at the stimulation and recording sites. The second specific aim is to understand the processing of spatial information near the time of a saccade. A saccade is a critical moment when our visual processing is dramatically challenged, leading to large localization errors. We investigate similar errors - giving rise to robust illusions - when the location of changing visual stimuli is compared to the location of brief steady stimuli. Psychophysical experiments are conducted with humans. The objective is to find a general explanation of various phenomena of mislocalization.
|
0.958 |