We are testing a new system for linking grants to scientists.
The funding information displayed below comes from the
NIH Research Portfolio Online Reporting Tools and the
NSF Award Database.
The grant data on this page is limited to grants awarded in the United States and is thus partial. It can nonetheless be used to understand how funding patterns influence mentorship networks and vice-versa, which has deep implications on how research is done.
You can help! If you notice any innacuracies, please
sign in and mark grants as correct or incorrect matches.
Sign in to see low-probability grants and correct any errors in linkage between grants and researchers.
High-probability grants
According to our matching algorithm, Nini Guo is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
2007 — 2008 |
Guo, Nini |
F32Activity Code Description: To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in specified health-related areas. |
The Hedgehog Pathway in Injury-Associated Pancreatic Carcinogenesis @ Johns Hopkins University
[unreadable] DESCRIPTION (provided by applicant): Hedgehog (Hh) pathway activity is important for the growth of a significant fraction of human cancers and is also implicated in stem cell maintenance in postembryonic tissues. Our preliminary results suggest that the Hh pathway is activated during tissue repair in response to acute injury in adult pancreas. We hypothesize that injury-induced pathway activation results in the expansion of tissue stem cells, and that inappropriate continuation of pathway activity may initiate cancer growth by transforming these cells into cancer stem cells. This hypothesis will be evaluated by assessing the stem cell character of cells with pathway activity induced by tissue injury and by testing whether continuous pathway activity in these cells can induce tumor formation. Various approaches including immunohistochemistry, cell culture, flow cytometry and mouse models will be used. Completion of these studies will expand our understanding of the mechanism by which Hh pathway activity causes growth of injury-associated tumors and provide a basis for using Hh pathway blockade as a new approach in human cancer therapy. [unreadable] [unreadable] [unreadable]
|
1 |