We are testing a new system for linking grants to scientists.
The funding information displayed below comes from the
NIH Research Portfolio Online Reporting Tools and the
NSF Award Database.
The grant data on this page is limited to grants awarded in the United States and is thus partial. It can nonetheless be used to understand how funding patterns influence mentorship networks and vice-versa, which has deep implications on how research is done.
You can help! If you notice any innacuracies, please
sign in and mark grants as correct or incorrect matches.
Sign in to see low-probability grants and correct any errors in linkage between grants and researchers.
High-probability grants
According to our matching algorithm, Jakub P. Jedynak is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
2005 — 2007 |
Jedynak, Jakub P |
F31Activity Code Description: To provide predoctoral individuals with supervised research training in specified health and health-related areas leading toward the research degree (e.g., Ph.D.). |
Visualizing Neuronal Morphology by Viral Gene Expression @ University of Michigan At Ann Arbor
DESCRIPTION (provided by applicant): Repeated administration of psychostimulant drugs such as cocaine and amphetamine produces long lasting neuroadaptations in the brain, including alterations in dendritic branching and spine density of medium spiny neurons of the nucleus accumbens (Acb) and pyramidal neurons of the medial prefrontal cortex (MPC). The overall aim of the application is to develop and apply viral expression technology with confocal microscopy to visualize and characterize drug-induced alterations of neuronal morphology. First, green fluorescent protein (GFP) will be virally overexpressed in vivo in order to visualize dendritic branches and spines in Acb and MPC of rats. Second, viral-mediated gene transfer will be employed, as an alternative to Golgi staining, to determine whether repeated exposure to amphetamine or cocaine produces morphological changes in neurons of the striatum and MPC. Third, in order to examine whether psychostimulant induced structural plasticity involve alterations in synaptic protein distribution in these brain regions, different fusion proteins such as actin or PSD-95 conjugated to GFP will be expressed. The proposed experiments will provide important new insights into the mechanisms underlying drug-experience dependent plasticity in the brain.
|
1 |