Area:
Basal Ganglia Learning & Memory
We are testing a new system for linking grants to scientists.
The funding information displayed below comes from the
NIH Research Portfolio Online Reporting Tools and the
NSF Award Database.
The grant data on this page is limited to grants awarded in the United States and is thus partial. It can nonetheless be used to understand how funding patterns influence mentorship networks and vice-versa, which has deep implications on how research is done.
You can help! If you notice any innacuracies, please
sign in and mark grants as correct or incorrect matches.
Sign in to see low-probability grants and correct any errors in linkage between grants and researchers.
High-probability grants
According to our matching algorithm, David Paxton Daberkow is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
2005 |
Daberkow, David Paxton |
F31Activity Code Description: To provide predoctoral individuals with supervised research training in specified health and health-related areas leading toward the research degree (e.g., Ph.D.). |
Methamphetamine, Procedural Learning, and Plasticity
DESCRIPTION (provided by applicant): The major goal of this project will be to examine how methamphetamine (METH)-induced monoamine depletions affect basal ganglia-mediated learning and the expression of three molecules thought to be critically involved in learning and memory function (c-fos, zif268, arc) in the dorsal striatum. We hypothesize that METH-induced monoamine depletions will impair basal ganglia-mediated learning and alter the normal expression of molecules associated with synaptic plasticity in the dorsal striatum. The basic experimental design will be to treat rats with a neurotoxic regimen of METH, known to induce monoamine depletions in the basal ganglia. These METH-treated rats, along with controls, will then be trained on a basal gangliadependent motor-response learning task in a plus maze. Once the rats meet motor-response learning criterion, the brains will be removed and processed for in situ hybridization to identify c-fos, zif268, and arc mRNA expression in identified efferent neuron populations of the dorsal striatum. This work will lead to a better understanding of how METH abuse affects normal learning and memory function and will provide insight into how changes in brain chemistry induced by drugs of abuse might lead to drug addiction.
|
0.965 |