Sharon L. Juliano - US grants

Affiliations:

Uniformed Services University of the Health Sciences, Bethesda, MD

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High-probability grants

According to our matching algorithm, Sharon L. Juliano is the likely recipient of the following grants.

Years	Recipients	Code	Title / Keywords	Matching score
1985	Juliano, Sharon L	F32Activity Code Description: To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in specified health-related areas.	Modular Information Processing in Somatosensory @ University of North Carolina Chapel Hill	0.939
1986 — 2010	Juliano, Sharon L	R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.	Structural Correlates of Cortical Information Processing @ Henry M. Jackson Fdn For the Adv Mil/Med embryo /fetus tissue transplantation; neocortex; neuroanatomy; nervous system transplantation; neural information processing; nonhuman therapy evaluation; vimentin; afferent nerve; cell migration; methanol; neurogenesis; developmental neurobiology; neurotoxins; neurons; tissue /cell culture; immunocytochemistry; ferrets; bromodeoxyuridine; Show keywords Hide keywords	0.913
1991	Juliano, Sharon L	R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.	Immunocytochemistry of Vestibular Nuclei @ Henry M. Jackson Fdn For the Adv Mil/Med vestibular pathway; choline acetyltransferase; dopamine beta monooxygenase; neurotransmitters; substance P; neuropeptide Y; enkephalins; cholecystokinin; serotonin; gamma aminobutyrate; glutamates; neuropeptides; neuroanatomy; ganglions; immunofluorescence technique; Saimiri; cats; immunochemistry; Show keywords Hide keywords	0.913
2001 — 2005	Juliano, Sharon L	R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.	Radial Glia and Cajal Retzius Cells in Neuron Migration @ Henry M. Jackson Fdn For the Adv Mil/Med DESCRIPTION: (Adapted from the Investigator's Abstract) The proposed research utilizes a model of impaired neurodevelopment in the ferret that presents as a thin and disrupted cerebral cortex, with ectopic clusters of cells typical of cortical dysplasia. During generation of the earliest born neocortical layers, treatment with the antimitotic agent, methylazoxy methanol (MAM), disrupts radial glia, and results in abnormally situated Cajal Retzius cells. Features of the brain resulting from this treatment are an excellent model for study of migration defects. The current proposal investigates the following questions resulting from this model. (1) What causes the radial glia to become disorganized? (2) What prevents cells from migrating effectively into the neocortex? (3) What causes the Cajal Retzius cells to become disorganized? The hypothesis is that a radialization factor is present in normal cortex, and when it is provided to MAM-treated cortex, normal radial glial morphology can be restored. A second, related hypothesis is that the restoration of normal radial glial morphology can improve migration in MAM-treated cortex. These hypotheses will be tested and the biochemical nature of the radialization factor will be defined using organotypic and cell cultures and migration bioassays to analyze this system. Show summary Hide summary	0.913