Bradley T. Hyman, MD PhD - US grants

Affiliations: 
Neurology Massachusetts General Hospital and Harvard University, Boston, MA, United States 
Area:
neuropathophysiologic and genetic factors that underlie dementia.
Website:
http://dms.hms.harvard.edu/neuroscience/fac/hyman.php

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High-probability grants

According to our matching algorithm, Bradley T. Hyman is the likely recipient of the following grants.
Years Recipients Code Title / Keywords Matching
score
1989 — 1993 Hyman, Bradley T
R29Activity Code Description:
Undocumented code - click on the grant title for more information.

Pathological Alterations in Alzheimer's Disease

@ Massachusetts General Hospital

1
1994 — 1998 Hyman, Bradley T
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Apolipoprotein E and Alzheimers Disease

@ Massachusetts General Hospital

1
1994 — 1998 Hyman, Bradley T
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Structural and Molecular Correlates of Cognitive Function in Alzheimer's Disease

@ Harvard University (Medical School)

0.957
1995 — 1999 Hyman, Bradley T
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Neuropathological Alterations in Alzheimers Disease

@ Massachusetts General Hospital

1
1996 — 1998 Hyman, Bradley T
P01Activity Code Description:
For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal.

Core--Brain Microdissection, Rna and Protein Analysis

@ Massachusetts General Hospital

1
1996 — 1998 Hyman, Bradley T
P01Activity Code Description:
For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal.

Signature of Regional and Neuronal Vulnerability in Ad

@ Massachusetts General Hospital

1
1997 — 1999 Hyman, Bradley T
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Presenilins and Alzheimers Disease

@ Massachusetts General Hospital

1
1998 — 2002 Hyman, Bradley T
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Role of Alpha Synuclein in Lewy Body Disease

@ Massachusetts General Hospital

1
1998 — 2002 Hyman, Bradley T
P01Activity Code Description:
For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal.

Transgenics and Presenilin Function

@ Brigham and Women's Hospital

0.94
1999 — 2002 Hyman, Bradley T
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Apoe and Transgenic Models of Alzheimers Disease

@ Massachusetts General Hospital

1
1999 — 2002 Hyman, Bradley T
P01Activity Code Description:
For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal.

Genetic Modifiers of Amyloid Beta Deposition--Neuroanatomic Correlates

@ University of Minnesota Twin Cities

0.916
2000 — 2011 Hyman, Bradley T.
R37Activity Code Description:
To provide long-term grant support to investigators whose research competence and productivity are distinctly superior and who are highly likely to continue to perform in an outstanding manner. Investigators may not apply for a MERIT award. Program staff and/or members of the cognizant National Advisory Council/Board will identify candidates for the MERIT award during the course of review of competing research grant applications prepared and submitted in accordance with regular PHS requirements.

Lrp and Alzheimer's Disease

@ Massachusetts General Hospital

1
2001 — 2005 Hyman, Bradley T
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Neuroanatomical Alterations in Alzheimer's Disease

@ Massachusetts General Hospital

1
2002 Hyman, Bradley T
P01Activity Code Description:
For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal.

Core--Neuropathology

@ Massachusetts General Hospital

1
2004 — 2010 Hyman, Bradley T
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Anatomical Changes in Tau Trangenic Models

@ Massachusetts General Hospital

1
2004 — 2008 Hyman, Bradley T
P01Activity Code Description:
For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal.
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Core--Scientific

@ Massachusetts General Hospital

1
2004 — 2008 Hyman, Bradley T
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Molecular Chaperones in Lewy Body Diseases

@ Massachusetts General Hospital

1
2004 — 2008 Hyman, Bradley T
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Tau Alterations in Alzheimer's and Related Dementias

@ Massachusetts General Hospital

1
2006 — 2020 Hyman, Bradley T
P30Activity Code Description:
To support shared resources and facilities for categorical research by a number of investigators from different disciplines who provide a multidisciplinary approach to a joint research effort or from the same discipline who focus on a common research problem. The core grant is integrated with the center's component projects or program projects, though funded independently from them. This support, by providing more accessible resources, is expected to assure a greater productivity than from the separate projects and program projects.
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Massachusetts Alzheimer's Disease Research Center

@ Massachusetts General Hospital

1
2006 — 2010 Hyman, Bradley T
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Neurologic Alterations in Alzheimer's Disease

@ Massachusetts General Hospital

1
2007 Hyman, Bradley T
P01Activity Code Description:
For the support of a broadly based, multidisciplinary, often long-term research program which has a specific major objective or a basic theme. A program project generally involves the organized efforts of relatively large groups, members of which are conducting research projects designed to elucidate the various aspects or components of this objective. Each research project is usually under the leadership of an established investigator. The grant can provide support for certain basic resources used by these groups in the program, including clinical components, the sharing of which facilitates the total research effort. A program project is directed toward a range of problems having a central research focus, in contrast to the usually narrower thrust of the traditional research project. Each project supported through this mechanism should contribute or be directly related to the common theme of the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence, i.e., a system of research activities and projects directed toward a well-defined research program goal.

Gamma Secretase and Substrate Interactions

@ Brigham and Women's Hospital

0.94
2009 — 2013 Hyman, Bradley T.
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Administrative

@ Massachusetts General Hospital

1
2009 — 2010 Hyman, Bradley T.
P30Activity Code Description:
To support shared resources and facilities for categorical research by a number of investigators from different disciplines who provide a multidisciplinary approach to a joint research effort or from the same discipline who focus on a common research problem. The core grant is integrated with the center's component projects or program projects, though funded independently from them. This support, by providing more accessible resources, is expected to assure a greater productivity than from the separate projects and program projects.

Faculty Recruitment For Programs in the Biology of Age-Related Cognitive Change

@ Massachusetts General Hospital

1
2009 — 2013 Hyman, Bradley T.
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Neuropathological Correlates of Oligomeric Amyloid Beta

@ Massachusetts General Hospital

1
2009 — 2011 Hyman, Bradley T.
RC1Activity Code Description:
NIH Challenge Grants in Health and Science Research

Peripherally Administered Gene Therapy For Alzheimer's

@ Massachusetts General Hospital

1
2010 — 2014 Hyman, Bradley T.
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Anatomical Changes in Tau Transgenic Models

@ Massachusetts General Hospital

1
2011 — 2012 Hyman, Bradley T.
R21Activity Code Description:
To encourage the development of new research activities in categorical program areas. (Support generally is restricted in level of support and in time.)

A Model of Early Alzheimer Disease

@ Massachusetts General Hospital

1
2011 — 2015 Hyman, Bradley T.
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Calcineurin-Mediated Neurodegeneration in Alzheimer Disease

@ Massachusetts General Hospital

1
2014 Hyman, Bradley T.
R34Activity Code Description:
To provide support for the initial development of a clinical trial or research project, including the establishment of the research team; the development of tools for data management and oversight of the research; the development of a trial design or experimental research designs and other essential elements of the study or project, such as the protocol, recruitment strategies, procedure manuals and collection of feasibility data.

Center For Alzheimer Therapeutic Science: Cats

@ Massachusetts General Hospital

1
2014 — 2018 Hyman, Bradley T.
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Core a: Administrative Core

@ Massachusetts General Hospital

1
2014 — 2018 Hyman, Bradley T.
P50Activity Code Description:
To support any part of the full range of research and development from very basic to clinical; may involve ancillary supportive activities such as protracted patient care necessary to the primary research or R&D effort. The spectrum of activities comprises a multidisciplinary attack on a specific disease entity or biomedical problem area. These grants differ from program project grants in that they are usually developed in response to an announcement of the programmatic needs of an Institute or Division and subsequently receive continuous attention from its staff. Centers may also serve as regional or national resources for special research purposes.

Mouse Model of Early Alzheimer's Disease

@ Massachusetts General Hospital

1
2018 Hyman, Bradley T.
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Are Multiple Tau Species Toxic in Alzheimer's Disease?

@ Massachusetts General Hospital

1
2018 Hyman, Bradley T.
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Synergy Between Amyloid and Tau in Alzheimer's Disease

@ Massachusetts General Hospital

1
2019 — 2020 Hyman, Bradley T.
P30Activity Code Description:
To support shared resources and facilities for categorical research by a number of investigators from different disciplines who provide a multidisciplinary approach to a joint research effort or from the same discipline who focus on a common research problem. The core grant is integrated with the center's component projects or program projects, though funded independently from them. This support, by providing more accessible resources, is expected to assure a greater productivity than from the separate projects and program projects.

Administrative Core

@ Massachusetts General Hospital

1
2019 Hyman, Bradley T.
R56Activity Code Description:
To provide limited interim research support based on the merit of a pending R01 application while applicant gathers additional data to revise a new or competing renewal application. This grant will underwrite highly meritorious applications that if given the opportunity to revise their application could meet IC recommended standards and would be missed opportunities if not funded. Interim funded ends when the applicant succeeds in obtaining an R01 or other competing award built on the R56 grant. These awards are not renewable.

Complexity and Heterogeneity of Alzheimer Disease

@ Massachusetts General Hospital

1
2019 — 2020 Hyman, Bradley T.
R21Activity Code Description:
To encourage the development of new research activities in categorical program areas. (Support generally is restricted in level of support and in time.)

Liquid Liquid Phase Separation and Tau Biology

@ Massachusetts General Hospital

1
2019 Holtzman, David M. [⬀]
Hyman, Bradley T.
R01Activity Code Description:
To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.

Novel Strategies and Mechanisms to Target Apoe and Alzheimer's Disease

@ Washington University

0.948