Eric A. Schwartz - US grants

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Retinal synapses

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High-probability grants

According to our matching algorithm, Eric A. Schwartz is the likely recipient of the following grants.

Years	Recipients	Code	Title / Keywords	Matching score
1985 — 2003	Schwartz, Eric A	R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies. R37Activity Code Description: To provide long-term grant support to investigators whose research competence and productivity are distinctly superior and who are highly likely to continue to perform in an outstanding manner. Investigators may not apply for a MERIT award. Program staff and/or members of the cognizant National Advisory Council/Board will identify candidates for the MERIT award during the course of review of competing research grant applications prepared and submitted in accordance with regular PHS requirements.	Synaptic Function in Photoreceptors of a Vertebrate Eye @ University of Chicago DESCRIPTION (Adapted from the applicant's abstract): The research program is a study of synaptic transmission in the vertebrate retina. The experiments will combine optical and electrophysiological methods. Complementary experiments will investigate vesicle cycling in dissociated cells and the transmission between identified cells in a retinal slice. The experiments will use mammalian and, when possible, non-mammalian preparations. Five specific aims are proposed: (1) to determine the Ca2+ dependence of synaptic vesicle cycling (in mammalian cones); (2) to determine if continuous and transient vesicle cycling are produced by a common molecular mechanism (in bipolar cells); (3) to determine the role of intracellular Ca2+ stores in transmitter release (from rod photoreceptors and bipolar cells); (4) to determine the role of a cGMP-gated current in transmitter release (from cone photoreceptors); and (5) to determine if mammalian cone photoreceptors release transmitter at basal junctions. Show summary Hide summary	1
1996 — 1999	Schwartz, Eric A	R01Activity Code Description: To support a discrete, specified, circumscribed project to be performed by the named investigator(s) in an area representing his or her specific interest and competencies.	Electrophysiology of Synaptic Transmitter Transporters @ University of Chicago A new research program in directed toward understanding the function of sodium co-transport carriers that control the extracellular concentrations of major neurotransmitters in the mammalian brain. Experiments will identify GABA and glutamate transporters that play essential roles in synaptic transmission. Methods in molecular biology and electrophysiology will be combined to provide a structural and functional analysis. Specific experiments will: 1) Examine the electrophysiological properties of the gene products expressed by GABA transporters isolated from the rat brain and expressed in stable cell lines. The electrophysiology of the transporters will be compared. 2) Clone the cDNA of a GABA transporter expressed in horizontal cells of the catfish retina. Compare the electrophysiology of the native transporter expressed in horizontal cells and the single protein expressed in a stable cell line. 3) Clone the cDNA of a glutamate transporter expressed in Muller glial cells of the salamander retina. Compare the electrophysiology of the native transporter expressed in Muller glial cells and the single protein expressed in a stable cell line. Show summary Hide summary	1
2004	Schwartz, Eric A	P41Activity Code Description: Undocumented code - click on the grant title for more information.	Analysis /Vesicle Cycling /Total Internal Reflection Mic @ University of California San Diego Abstract not provided. Show summary Hide summary	0.964
2005	Schwartz, Eric A	P41Activity Code Description: Undocumented code - click on the grant title for more information.	Analysis of Vesicle Cycling by Total Internal Reflection Microscopy @ University of California San Diego bioimaging /biomedical imaging; technology /technique development Show keywords Hide keywords	0.964