We are testing a new system for linking grants to scientists.
The funding information displayed below comes from the
NIH Research Portfolio Online Reporting Tools and the
NSF Award Database.
The grant data on this page is limited to grants awarded in the United States and is thus partial. It can nonetheless be used to understand how funding patterns influence mentorship networks and vice-versa, which has deep implications on how research is done.
You can help! If you notice any innacuracies, please
sign in and mark grants as correct or incorrect matches.
Sign in to see low-probability grants and correct any errors in linkage between grants and researchers.
High-probability grants
According to our matching algorithm, Eric J. Gonzalez is the likely recipient of the following grants.
Years |
Recipients |
Code |
Title / Keywords |
Matching score |
2020 — 2021 |
Gonzalez, Eric J |
K01Activity Code Description: For support of a scientist, committed to research, in need of both advanced research training and additional experience. |
Underactive Bladder: Mechanisms and Recovery of Sensation and Function
PROJECT SUMMARY Candidate (Eric J. Gonzalez, PhD): My long-term career goal is to develop a peripheral nerve stimulation device to manage lower urinary tract symptoms and improve bladder emptying in underactive bladder. I am seeking a Mentored Research Scientist Development Award (K01) to expand my translational research program and develop leadership skills to independently manage a research team. The K01 award will provide me with mentored training in human subjects research, didactic clinical coursework, and protected time for professional development. Environment: My career development will be guided by a multidisciplinary team with proven expertise in neural engineering, clinical research, basic science, and biostatistics. My training will be implemented at Duke University, a world-class academic medical center with innovative scientific research laboratories and neighboring medical facilities that enable rapid translation of novel ideas. Research: Underactive bladder is an understudied health concern that occurs in diverse patient populations and exhibits an age-related increase in prevalence. The palliative management options for persons with underactive bladder are associated with poor quality of life and patients often fail to completely resolve lower urinary tract symptoms. In order to improve therapeutic outcomes, there is a need to clarify the pathological mechanisms underlying underactive bladder. The objective of this proposal is to determine the role of motor and sensory nerve drive in the development of underactivity in a novel animal model, as well as in women with underactive bladder. We will first utilize a novel rat model of underactivity to determine the mechanisms of reduced motor drive and efficacy of pharmacological treatments and electrical neuromodulation in improving bladder emptying (Aim 1). We will also quantify the contributions of reduced sensory drive to the pathophysiology of lower urinary tract symptoms in neurologically-intact adult women with underactive bladder and determine the efficacy of electrical neuromodulation in resolving symptoms (Aim 2). These studies will increase our understanding of the muscular and neural alterations in the lower urinary tract that may accompany underactive bladder and will provide a foundation for clinicians to develop innovative therapeutics to improve patient outcomes.
|
1 |